ethical committee, needs of nursing ethics, code of ethics, purposes of code of ethics, laws , types of laws, torts , laws in nursing , responsibility of nurses in law , classification of torts
Ethics presentation given at Providence Health Care on 2/19/16 as a part of a day-long nursing oncology conference. Discusses the fundamental clinical ethics consultation approach and discusses in narrative the relevant ethics cases that are common to oncology practice
ethical committee, needs of nursing ethics, code of ethics, purposes of code of ethics, laws , types of laws, torts , laws in nursing , responsibility of nurses in law , classification of torts
Ethics presentation given at Providence Health Care on 2/19/16 as a part of a day-long nursing oncology conference. Discusses the fundamental clinical ethics consultation approach and discusses in narrative the relevant ethics cases that are common to oncology practice
Ethical aspects of clinical laboratory staff, Doctors, Pharmacists, Health information managers, Nurses, Physiotherapists and other healthcare professionals in their respective services.
When facing critical illness, ethical considerations loom large, guiding decisions that profoundly affect individuals and their loved ones. In such scenarios, principles like autonomy, beneficence, non-maleficence, and justice become paramount.
Autonomy, the right to self-determination, acknowledges the patient's ability to make decisions regarding their care. However, in cases like the 84-year-old who underwent aneurysm surgery, cognitive impairment or advanced age may compromise autonomy, necessitating surrogate decision-making.
Beneficence and non-maleficence dictate the obligation to act in the patient's best interest while avoiding harm. The story of the 84-year-old illustrates this balance. While surgery aimed to prolong life, it inadvertently led to limitations, such as the inability to engage fully in activities like playing with grandchildren.
Justice concerns the fair distribution of resources and burdens. In the context of critical illness, it prompts questions about equitable access to care and allocation of medical resources. For instance, the emotional toll on the family of the baby who didn't survive may raise questions about the allocation of resources for neonatal care.
These ethical principles intersect with personal narratives, such as the 84-year-old's desire to participate in family activities or the grief of losing a baby. They guide clinicians, families, and policymakers in navigating complex decisions, seeking to uphold dignity, respect, and the best possible outcomes amidst challenging circumstances.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ethical aspects of clinical laboratory staff, Doctors, Pharmacists, Health information managers, Nurses, Physiotherapists and other healthcare professionals in their respective services.
When facing critical illness, ethical considerations loom large, guiding decisions that profoundly affect individuals and their loved ones. In such scenarios, principles like autonomy, beneficence, non-maleficence, and justice become paramount.
Autonomy, the right to self-determination, acknowledges the patient's ability to make decisions regarding their care. However, in cases like the 84-year-old who underwent aneurysm surgery, cognitive impairment or advanced age may compromise autonomy, necessitating surrogate decision-making.
Beneficence and non-maleficence dictate the obligation to act in the patient's best interest while avoiding harm. The story of the 84-year-old illustrates this balance. While surgery aimed to prolong life, it inadvertently led to limitations, such as the inability to engage fully in activities like playing with grandchildren.
Justice concerns the fair distribution of resources and burdens. In the context of critical illness, it prompts questions about equitable access to care and allocation of medical resources. For instance, the emotional toll on the family of the baby who didn't survive may raise questions about the allocation of resources for neonatal care.
These ethical principles intersect with personal narratives, such as the 84-year-old's desire to participate in family activities or the grief of losing a baby. They guide clinicians, families, and policymakers in navigating complex decisions, seeking to uphold dignity, respect, and the best possible outcomes amidst challenging circumstances.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
3. What is AETCOM?
Refers to Attitude, Ethics and Communication
competencies for IMG
Overall goal:
• to create IMG possessing requisite knowledge, skills, attitudes,
values and responsiveness, so that he or she may function
appropriately and effectively as a physician of first contact of
the community while being globally relevant.
4.
5. The Hidden Curriculum
• Professionalism -attributes, behaviors, commitments, values, and goals
that characterize a profession.
• Ethics refers to careful and systematic analysis of moral decisions and
behaviors and practicing those decisions.
• Ethical principles such as respect for persons, informed consent, and
confidentiality are basic tenets of medical practice.
• Traditionally, professionalism and ethics diffused passively by watching
teachers and seniors
6. Is it really needed to teach attitude and
communication skills to medical students?
9. • Ability to communicate adequately, sensitively, effectively and respectfully
with patients in a language that the patient understands and in a manner
that will improve patient satisfaction and health care outcomes.
• Ability to communicate with patients in a manner respectful of patient’s
preferences, values, prior experience, beliefs, confidentiality and privacy.
• Ability to communicate with patients, colleagues and families in a manner
that encourages participation and shared decision-making.
10.
11. What does ‘Professional’ mean?
• Committed to excellence, is ethical, responsive and accountable to patients,
community and the profession
• Practices selflessness, integrity, responsibility, accountability and respect.
• Respects and maintains professional boundaries between patients, colleagues and
society.
• Ability to recognize and manage ethical and professional conflicts.
• Abides by prescribed ethical and legal codes of conduct and practice.
12. What does ‘Professional’ mean?
Committed to
• excellence
• is ethical
• responsive
Accountable to
• patients
• community
• profession
Practices
• selflessness
• integrity
• responsibility
• accountability
• respect
13. What does ‘Professional’ mean?
Abides by prescribed ethical and legal codes of conduct
and practice.
Ability to recognize and manage ethical and professional
conflicts.
Respects and maintains professional boundaries between
patients colleagues society
14. Two major aspects of teaching professionalism include
Explicit teaching of cognitive base
stage appropriate opportunities for
experiential learning and reflection
throughout the curriculum.
The domains of attitude and communications with
emphasis on ethics therefore need to be taught directly
and explicitly throughout the curriculum.
15. What is New in Attitude and Communication Module?
Strives to strike
a balance
between explicit
teaching and
experiential
learning.
Explicit
teaching
Experiential
learning
16. Communication Skill
• Building the doctor patient relationship - Body Language, Introduction.
• Opening the discussion – Gaining Confidence.
• Gathering information
• Understanding the patient’s perspective – Physical / Emotional / Social
• Sharing information – Medical Advice.
• Reaching agreement on problems and plans – Discuss treatment options.
• Providing closure – Future course / Follow up
17. Breaking a bad news
SPIKES- Six- Step Protocol for Delivering Bad News
• Step 1: S- Setting Up The Interview
• Step 2: P- Assessing The Patient’s Perception
• Step 3: I- Obtaining The Patient’s Invitation
• Step 4: K- Giving Knowledge And Information To The Patient
• Step 5: E- Addressing The Patient’s Emotions With Empathic Responses
• Step 6: S- Strategy and Summary
19. A 54 year old man named Mr. Surendra Patel is admitted for acute chest pain in a medical centre. His
father had died of a myocardial infarction at the age of 60. Two years ago, his brother had been admitted to
a hospital with a myocardial infarction and had died after complications following an angioplasty. Mr.
Patel is a diabetic and is on multiple oral hypoglycemic agents with moderate control. After initial
stabilization, the patient is comfortable and pain-free after analgesics, nitrates and statins. Preliminary
blood tests and ECG confirm an acute coronary event. The next morning, the senior cardiologist makes
rounds and reviews the patient. “You have unstable angina, Mr. Patel and require an angiogram. You may
also require either a stent or coronary bypass after the procedure. The nurse will provide you with the
necessary paperwork. Please sign it and I will plan the procedure for 4.35 AM tomorrow morning.”.
“Doctor sahib”, asked Mr. Patel, “I am not comfortable with the idea of an angiogram; my brother died on
the table when an angioplasty was being done. Aren’t there other tests thatyou can do? I am not happy
with this option”. “Your brother would have had it with someone else, Mr. Patel - I have the best hands in
town; nothing will happen when I do it” retorted the cardiologist. “But aren’t there any other options to see
what I have? Is this the only test? I have read somewhere that you can do a CT angiogram”, persisted Mr.
Patel. “Are you the doctor or am I the doctor?” retorted the cardiologist angrily. “If you are ready to do as
I say, sign the papers and I will see you in the Cath lab tomorrow. Otherwise you are free to get
discharged”. He stomped out.
20. Points for discussion
1. Extent of patient autonomy.
2. Informed consent and informed refusal.
3. Conflict between autonomy and beneficence.
4. What should the patient be told about a procedure?
5. What must the informed consent include?
21.
22. • List of resources :
• Attitude, Ethics and Communication (AETCOM) Competencies for the Indian Medical Graduate - Medical
Council of India
• Jonathan Martin, Margaret Lloyd and Surinder Singh. Professional attitudes: can they be taught and
assessed in medical education. Clinical Medicine Vol 2 No 3 May/June 2002 217
• Walter f. Baile, Robert Buckman, Renato Lenzi, Gary Glober, Estela a. Beale, Andrzej p. Kudelkab.
Spikes—a six-step protocol for delivering bad news: Application to the patient with cancer The
oncologist 2000;5:302-311
• Whitcomb ME. What does it mean to be a physician? Acad Med.2007; 82: 917-8.
• Eisenberg C. It is still a privilege to be a doctor? N Engl J Med 1986; 314:1113-1114.