This document discusses common problems that occur with Hazard and Operability (HAZOP) studies. It notes that while guidelines for best practices in HAZOP studies exist, in practice it can be difficult to fully follow best practices. Some common issues include using HAZOP by difference for repetitive designs without fully considering differences in process conditions, and reluctance of vendors to acknowledge potential issues with their package designs. Additionally, there has been a trend to reduce the scope of HAZOPs to only safety and environmental issues, excluding operability and reliability. With financial pressures, these problems are expected to increase as projects face pressure to reduce costs and scope. The document explores some potential solutions to these common HAZOP challenges.
This document discusses the application of ICH Q8 and Q10 principles to pharmaceutical product development and manufacturing. It begins with an example of a dissolution failure incident to highlight the importance of understanding products and processes. It then outlines tools and approaches like knowledge management and quality risk management that can be used from development through commercial manufacturing following ICH Q8 and Q10 guidelines. Finally, it provides a case study example of how these principles were applied to the development of the drug Saxagliptin.
Analyze and Optimize Your Supply Chain Operations for Higher Performance - OM...April Bright
The operations science pioneered through Factory Physics provides practical concepts to analyze and optimize supply chain operations. This presentation covers basic approaches for operations science to enhance your world, with all its variability in product mix, demand, people and processes. You will get applications of the science to apply immediately.
QMS Effectiveness: Tracking and Trending Quality Data - OMTEC 2017April Bright
What measurements are useful, and which metrics’ baseline makes sense to show the effectiveness of your quality management system? This presentation takes an ISO 13485 and 21 CFR, Part 820 approach to deciding what measurements are important, how trending makes an impact on risk-based decision-making, and why management review is just one of the ways to discuss and document your Quality Data activities.
The document provides an overview of risk assessment methods. It discusses requirements for risk assessment at top tier and lower tier industrial sites according to EU directives. It defines hazards and risk, and describes risk assessment as identifying hazards, quantifying risks, and determining safety measures. Key steps in risk assessment include hazard identification, analysis of accident scenarios, consequence analysis, and risk estimation. Common hazard identification methods like HAZOP, checklists, and fault tree analysis are outlined. The document emphasizes that risk assessment is a team effort and continuous process.
Guidelines for Safe Pre-commissioning, Commissioning, and Operation of Proces...Karl Kolmetz
This seminar focuses on the core building blocks of the process unit equipment.
This program will emphasize process unit equipment fundamentals, safe
utilization of these fundamentals by operations and maintenance personnel, and
equipment troubleshooting techniques.
This document discusses risk assessment and management for quarries. It outlines the objectives of risk assessment, defines risk management principles, and describes various risk assessment methodologies including qualitative, quantitative, failure modes and effects analysis, and hazard and operability studies. The stages of risk management are identified as hazard identification, risk evaluation, and risk control. UK health and safety legislation requires employers to conduct suitable and efficient risk assessments to identify necessary risk control measures.
The document discusses emerging challenges related to ICH Q8 and Q10 implementation, including increased risk and non-compliance due to process variability. It also discusses how quality inspectors and assessors can evaluate product control strategy, quality by design, manufacturing processes, and change management systems. The rest of the document focuses on knowledge management, data integrity, and quality metrics as indicators of operational reliability and quality culture. Key quality metrics discussed include lot acceptance rate, product quality complaint rate, right first time rate, invalidated OOS rate, APR/PQR on time rate, CAPA rate, and ability to initiate voluntary CAPA.
Implementing an effective Electronic CAPA Management SystemLornae
For all organisations who are required to manage their CAPA processes to maintain regulatory compliance, and who are struggling with a manual paper-based system. This informative presentation will cover:-
-Regulatory requirements for CAPA
-Elements of effective CAPA systems
-How and why your CAPA processes should integrate with other compliance activities
-Benefits of implementing an electronic CAPA management system 'v' a manual one
This document discusses the application of ICH Q8 and Q10 principles to pharmaceutical product development and manufacturing. It begins with an example of a dissolution failure incident to highlight the importance of understanding products and processes. It then outlines tools and approaches like knowledge management and quality risk management that can be used from development through commercial manufacturing following ICH Q8 and Q10 guidelines. Finally, it provides a case study example of how these principles were applied to the development of the drug Saxagliptin.
Analyze and Optimize Your Supply Chain Operations for Higher Performance - OM...April Bright
The operations science pioneered through Factory Physics provides practical concepts to analyze and optimize supply chain operations. This presentation covers basic approaches for operations science to enhance your world, with all its variability in product mix, demand, people and processes. You will get applications of the science to apply immediately.
QMS Effectiveness: Tracking and Trending Quality Data - OMTEC 2017April Bright
What measurements are useful, and which metrics’ baseline makes sense to show the effectiveness of your quality management system? This presentation takes an ISO 13485 and 21 CFR, Part 820 approach to deciding what measurements are important, how trending makes an impact on risk-based decision-making, and why management review is just one of the ways to discuss and document your Quality Data activities.
The document provides an overview of risk assessment methods. It discusses requirements for risk assessment at top tier and lower tier industrial sites according to EU directives. It defines hazards and risk, and describes risk assessment as identifying hazards, quantifying risks, and determining safety measures. Key steps in risk assessment include hazard identification, analysis of accident scenarios, consequence analysis, and risk estimation. Common hazard identification methods like HAZOP, checklists, and fault tree analysis are outlined. The document emphasizes that risk assessment is a team effort and continuous process.
Guidelines for Safe Pre-commissioning, Commissioning, and Operation of Proces...Karl Kolmetz
This seminar focuses on the core building blocks of the process unit equipment.
This program will emphasize process unit equipment fundamentals, safe
utilization of these fundamentals by operations and maintenance personnel, and
equipment troubleshooting techniques.
This document discusses risk assessment and management for quarries. It outlines the objectives of risk assessment, defines risk management principles, and describes various risk assessment methodologies including qualitative, quantitative, failure modes and effects analysis, and hazard and operability studies. The stages of risk management are identified as hazard identification, risk evaluation, and risk control. UK health and safety legislation requires employers to conduct suitable and efficient risk assessments to identify necessary risk control measures.
The document discusses emerging challenges related to ICH Q8 and Q10 implementation, including increased risk and non-compliance due to process variability. It also discusses how quality inspectors and assessors can evaluate product control strategy, quality by design, manufacturing processes, and change management systems. The rest of the document focuses on knowledge management, data integrity, and quality metrics as indicators of operational reliability and quality culture. Key quality metrics discussed include lot acceptance rate, product quality complaint rate, right first time rate, invalidated OOS rate, APR/PQR on time rate, CAPA rate, and ability to initiate voluntary CAPA.
Implementing an effective Electronic CAPA Management SystemLornae
For all organisations who are required to manage their CAPA processes to maintain regulatory compliance, and who are struggling with a manual paper-based system. This informative presentation will cover:-
-Regulatory requirements for CAPA
-Elements of effective CAPA systems
-How and why your CAPA processes should integrate with other compliance activities
-Benefits of implementing an electronic CAPA management system 'v' a manual one
1) Dr. Obaid Ali discussed the appropriate use of Quality Risk Management (QRM) to facilitate regulatory compliance without removing industry's obligation to adhere to requirements.
2) The document defines key terms related to quality risk management including harm, hazard, hazardous situation, risk, residual risk, severity, and detectability based on ICH Q9 and ISO 14971.
3) Regulatory observations from authorities in France, South Africa, and the US FDA are presented that highlight failures to adequately perform risk assessment and management.
The document discusses improving quality performance issues at a third party warehouse supplier, DHL Global Forwarding, for Medtronic International Ltd. A recent audit found the warehouse to be dirty and messy with dust on machines and shelves. It also found issues with document control and standard operating procedures. Soft systems methodology will be used to help define the system, identify the problem areas, and propose solutions. The objectives are to eliminate or prevent the root causes of the quality issues found at DHL Global Forwarding's warehouse.
The primary responsibility of the post-close supply chain transition team is to achieve and maintain uninterrupted upstream supply and an excellent downstream customer experience while delivering the projected savings from the combined company. This presentation provides guidance on ways to identify, assess and avoid or minimize opportunities for supply chain disruption immediately after closing, as well as best practices for successful supply chain consolidation and integration.
Operations: Top Reasons for Long Lead Times and What to Do About ThemApril Bright
Long lead times remain one of the most vocalized challenges that orthopedic manufacturers face today. Customers, profits, plans and personnel are all negatively impacted by them. James Kwan has worked on the OEM and the supplier sides of orthopedics, and shared his ideas and successful experiences to help you optimally respond to lead times, reduce them and ultimately create and sustain an agile supply chain.
Program - American Chemical Manufacturing Summit 2013, PittsburghMark Blendheim
The American Chemical Manufacturing Summit brings together industry leaders to discuss the current state of the industry and the impact of new regulations. The summit provides chemical manufacturing, quality and supply chain executives valuable insight into new manufacturing strategies, technology and Operational Excellence.
It is all about the following statment :
"The ability to simplify means to eliminate the unnecessary so that the necessary may speak."
Hans Hofmann
This document discusses risk-based methods for innovative new product development. It emphasizes identifying and focusing on critical risks and areas of added value early in the development process. The document recommends (1) chopping the product and development process into smaller pieces to make risks more tangible, (2) using tools like visualization, simulation, testing and reviews to validate ideas quickly and cheaply, and (3) managing options throughout the process to maintain flexibility in the face of risks and uncertainties. The overall goal is to take a holistic, balanced approach that considers technical, schedule and cost risks to help innovations succeed.
The document discusses corrective and preventive actions (CAPA) for recurring problems. It explains that CAPA is a structured process required by ISO 9001 to investigate nonconformities, determine appropriate corrections and actions, and measure effectiveness. The CAPA process involves defining the problem, investigating the root cause, developing solutions, verifying the solutions address the root cause, and checking effectiveness. Root cause analysis tools discussed include 5 whys, cause-and-effect diagrams, IS/IS NOT analysis, and the 8D (eight disciplines) approach. The document emphasizes finding facts over fault to properly solve problems.
Refining Process Equipment Troubleshooting Karl Kolmetz
This document provides an overview of a training course on petroleum refining process equipment troubleshooting. The course aims to help operations teams understand fundamental process unit operations concepts in order to improve unit performance and on-stream time. It covers topics like distillation, furnaces, boilers, rotating equipment, piping, heat exchangers, and process control systems. Through lectures and case studies, participants will gain knowledge of troubleshooting principles, techniques, and best practices to identify and resolve issues in refineries and petrochemical plants. The course is intended for personnel involved in plant operations, maintenance, engineering, and technical services.
Vital QMS Process Validation Statistics - OMTEC 2018April Bright
According to 21 CFR, Part 820, medical device manufacturers are required to validate as well as monitor and control parameters for their processes. The guideline on Quality Management Systems does not specify how this is accomplished; only that “a process is established that can consistently conform to requirements” and “studies are conducted demonstrating” this. Thorough process development, optimization and control using appropriate statistical methods and tools is recommended for demonstrating that your process is both stable and capable. This session will demonstrate ways to efficiently and effectively apply recommended statistical methods and tools to process validation—with no statistical expertise needed. Using realistic process data, participants will learn how to apply tools, interpret results and draw meaningful conclusions throughout Installation Qualification (IQ), Operational Qualification (OQ) and Performance Qualification (PQ).
This document discusses three key elements of process safety risk management at the corporate level:
1) Hazard Identification and Risk Analysis (HIRA) to thoroughly understand risks through techniques like HAZOP, LOPA, and QRA.
2) Performance monitoring through regular PSM audits to identify gaps in risk management performance.
3) Tracking progress over time using Key Performance Indicators (KPIs) to understand how well the organization is managing identified process risks on both technical and leadership levels.
Together, these elements form an efficient system to drive RBPS practices through the organization and improve process safety results.
How to Implement TOC Principles and Tools in State Government and Achieve Gre...commonsenseLT
Kristen Cox, Executive Director, Governor’s Office of Management and Budget (USA) & Greg Gardner, Director of Operational Excellence for Utah Governor’s Office of Management and Budget (USA) @ TOCICO International Public Sector Effectiveness Conference 2013 Vilnius
- Overview of the SUCCESS Framework.
- Introduction of Utah’s measurement criteria.
- Introduction to the SUCCESS Management Information System (SMIS).
-Utah’s use of additional tools to assist agencies achieve great results.
-Utah’s progress to anchor the budgeting process to performance.
- Status of implementing the SUCCESS Framework across Utah’s 24 Cabinet agencies.
More information - http://pse.lt
This document discusses Corrective and Preventative Action (CAPA) systems. It defines CAPA as a quality system used to eliminate causes of nonconformities and prevent their recurrence. CAPA systems are required to minimize risks, meet regulatory requirements, and enable continuous improvement. Common mistakes include procedural failures, documentation errors, inadequate training, and failure to identify root causes or ensure corrective actions. A proper CAPA system aims to identify and address risks, incidents, training needs, and quality system weaknesses. The overview outlines the typical CAPA process of discovery, investigation, root cause analysis, corrective action, and follow up.
Introduction to Unit Operation Fundamentals and Troubleshooting Training CourseKarl Kolmetz
This document describes an introductory training course on unit operations fundamentals and troubleshooting. The course aims to help processing plant engineers and operators understand key concepts to improve safety, reliability, reduce costs and increase profits. It is taught over 3 to 5 days by a senior instructor and covers topics like mass transfer, fluid dynamics, heat transfer, reactions, and case studies. Attendees include operations and maintenance personnel who want to broaden their skills and apply concepts to optimize their facilities. The goal is for participants to leave with strategies to troubleshoot issues and increase operational excellence.
Pharmaceutical 6 Sigma and QbD May 2005 Ball State UniversityAjaz Hussain
Pharmaceutical product and process quality – what is the current “sigma”?
Challenges in moving towards “6-sigma” levels?
What are the steps necessary for the pharmaceutical continuous improvement journey in the 21st Century?
This document discusses corrective and preventive action (CAPA) systems and how they are used to mitigate risk. It provides three key points:
1) CAPA systems use non-conformances, deviations, and potential problems to investigate quality issues, identify corrective and preventive actions, and track the implementation of these actions.
2) CAPA aims to define the risk level associated with quality events and ensure appropriate actions are taken based on risk level, from further investigation and corrective actions for high risks to no action for low risks.
3) Effective CAPA systems incorporate change control to evaluate and document any changes made as a result of corrective actions to avoid introducing new risks.
Lean Six Sigma applications in healthcare require an understanding of how the tools and methodologies translate to the people-intensive processes of patient care. Once applied, the possibilities are endless. Using real-world examples of the most common types of errors in clinical services, participants will learn how the DMAIC structure within Lean Six Sigma will lead them to solutions that will prevent future errors.
Over the Top Process Safety Lessons Related to Liquid LevelAlan Munn
This document discusses lessons related to liquid level measurement in process vessels and tanks. It notes that level instruments often provide inaccurate readings due to design flaws, installation errors, or lack of understanding about how they work. This can lead to overfilling vessels. It discusses reasons for inaccurate readings, including instruments being calibrated for the wrong fluid density or temperature. Levels in standpipes or bypass lines may differ from vessel levels. Plugged tapping points also cause false readings. Poor operator understanding of instruments and "normalization of deviance" contribute to safety issues. Management of change and human factors need more attention to address level measurement problems.
This document summarizes a presentation on common errors in tank design that lead to safety incidents. The key points are:
1) Fires and explosions at storage tanks continue regularly despite basic tank technology remaining unchanged, showing lessons from past incidents are not being applied. An overreliance on vendors and seeing tanks as commodities leads to insufficient engineering input into design.
2) Modifications especially pose challenges as design errors are often missed. The author provides examples where miscommunication with vendors, lack of clear specifications, and lowest-cost mindsets compromised safety.
3) Specific cases highlight issues like mistaking small "blast hatches" for internal explosion protection and poor inlet distributor design increasing static risks. Overall,
1) Dr. Obaid Ali discussed the appropriate use of Quality Risk Management (QRM) to facilitate regulatory compliance without removing industry's obligation to adhere to requirements.
2) The document defines key terms related to quality risk management including harm, hazard, hazardous situation, risk, residual risk, severity, and detectability based on ICH Q9 and ISO 14971.
3) Regulatory observations from authorities in France, South Africa, and the US FDA are presented that highlight failures to adequately perform risk assessment and management.
The document discusses improving quality performance issues at a third party warehouse supplier, DHL Global Forwarding, for Medtronic International Ltd. A recent audit found the warehouse to be dirty and messy with dust on machines and shelves. It also found issues with document control and standard operating procedures. Soft systems methodology will be used to help define the system, identify the problem areas, and propose solutions. The objectives are to eliminate or prevent the root causes of the quality issues found at DHL Global Forwarding's warehouse.
The primary responsibility of the post-close supply chain transition team is to achieve and maintain uninterrupted upstream supply and an excellent downstream customer experience while delivering the projected savings from the combined company. This presentation provides guidance on ways to identify, assess and avoid or minimize opportunities for supply chain disruption immediately after closing, as well as best practices for successful supply chain consolidation and integration.
Operations: Top Reasons for Long Lead Times and What to Do About ThemApril Bright
Long lead times remain one of the most vocalized challenges that orthopedic manufacturers face today. Customers, profits, plans and personnel are all negatively impacted by them. James Kwan has worked on the OEM and the supplier sides of orthopedics, and shared his ideas and successful experiences to help you optimally respond to lead times, reduce them and ultimately create and sustain an agile supply chain.
Program - American Chemical Manufacturing Summit 2013, PittsburghMark Blendheim
The American Chemical Manufacturing Summit brings together industry leaders to discuss the current state of the industry and the impact of new regulations. The summit provides chemical manufacturing, quality and supply chain executives valuable insight into new manufacturing strategies, technology and Operational Excellence.
It is all about the following statment :
"The ability to simplify means to eliminate the unnecessary so that the necessary may speak."
Hans Hofmann
This document discusses risk-based methods for innovative new product development. It emphasizes identifying and focusing on critical risks and areas of added value early in the development process. The document recommends (1) chopping the product and development process into smaller pieces to make risks more tangible, (2) using tools like visualization, simulation, testing and reviews to validate ideas quickly and cheaply, and (3) managing options throughout the process to maintain flexibility in the face of risks and uncertainties. The overall goal is to take a holistic, balanced approach that considers technical, schedule and cost risks to help innovations succeed.
The document discusses corrective and preventive actions (CAPA) for recurring problems. It explains that CAPA is a structured process required by ISO 9001 to investigate nonconformities, determine appropriate corrections and actions, and measure effectiveness. The CAPA process involves defining the problem, investigating the root cause, developing solutions, verifying the solutions address the root cause, and checking effectiveness. Root cause analysis tools discussed include 5 whys, cause-and-effect diagrams, IS/IS NOT analysis, and the 8D (eight disciplines) approach. The document emphasizes finding facts over fault to properly solve problems.
Refining Process Equipment Troubleshooting Karl Kolmetz
This document provides an overview of a training course on petroleum refining process equipment troubleshooting. The course aims to help operations teams understand fundamental process unit operations concepts in order to improve unit performance and on-stream time. It covers topics like distillation, furnaces, boilers, rotating equipment, piping, heat exchangers, and process control systems. Through lectures and case studies, participants will gain knowledge of troubleshooting principles, techniques, and best practices to identify and resolve issues in refineries and petrochemical plants. The course is intended for personnel involved in plant operations, maintenance, engineering, and technical services.
Vital QMS Process Validation Statistics - OMTEC 2018April Bright
According to 21 CFR, Part 820, medical device manufacturers are required to validate as well as monitor and control parameters for their processes. The guideline on Quality Management Systems does not specify how this is accomplished; only that “a process is established that can consistently conform to requirements” and “studies are conducted demonstrating” this. Thorough process development, optimization and control using appropriate statistical methods and tools is recommended for demonstrating that your process is both stable and capable. This session will demonstrate ways to efficiently and effectively apply recommended statistical methods and tools to process validation—with no statistical expertise needed. Using realistic process data, participants will learn how to apply tools, interpret results and draw meaningful conclusions throughout Installation Qualification (IQ), Operational Qualification (OQ) and Performance Qualification (PQ).
This document discusses three key elements of process safety risk management at the corporate level:
1) Hazard Identification and Risk Analysis (HIRA) to thoroughly understand risks through techniques like HAZOP, LOPA, and QRA.
2) Performance monitoring through regular PSM audits to identify gaps in risk management performance.
3) Tracking progress over time using Key Performance Indicators (KPIs) to understand how well the organization is managing identified process risks on both technical and leadership levels.
Together, these elements form an efficient system to drive RBPS practices through the organization and improve process safety results.
How to Implement TOC Principles and Tools in State Government and Achieve Gre...commonsenseLT
Kristen Cox, Executive Director, Governor’s Office of Management and Budget (USA) & Greg Gardner, Director of Operational Excellence for Utah Governor’s Office of Management and Budget (USA) @ TOCICO International Public Sector Effectiveness Conference 2013 Vilnius
- Overview of the SUCCESS Framework.
- Introduction of Utah’s measurement criteria.
- Introduction to the SUCCESS Management Information System (SMIS).
-Utah’s use of additional tools to assist agencies achieve great results.
-Utah’s progress to anchor the budgeting process to performance.
- Status of implementing the SUCCESS Framework across Utah’s 24 Cabinet agencies.
More information - http://pse.lt
This document discusses Corrective and Preventative Action (CAPA) systems. It defines CAPA as a quality system used to eliminate causes of nonconformities and prevent their recurrence. CAPA systems are required to minimize risks, meet regulatory requirements, and enable continuous improvement. Common mistakes include procedural failures, documentation errors, inadequate training, and failure to identify root causes or ensure corrective actions. A proper CAPA system aims to identify and address risks, incidents, training needs, and quality system weaknesses. The overview outlines the typical CAPA process of discovery, investigation, root cause analysis, corrective action, and follow up.
Introduction to Unit Operation Fundamentals and Troubleshooting Training CourseKarl Kolmetz
This document describes an introductory training course on unit operations fundamentals and troubleshooting. The course aims to help processing plant engineers and operators understand key concepts to improve safety, reliability, reduce costs and increase profits. It is taught over 3 to 5 days by a senior instructor and covers topics like mass transfer, fluid dynamics, heat transfer, reactions, and case studies. Attendees include operations and maintenance personnel who want to broaden their skills and apply concepts to optimize their facilities. The goal is for participants to leave with strategies to troubleshoot issues and increase operational excellence.
Pharmaceutical 6 Sigma and QbD May 2005 Ball State UniversityAjaz Hussain
Pharmaceutical product and process quality – what is the current “sigma”?
Challenges in moving towards “6-sigma” levels?
What are the steps necessary for the pharmaceutical continuous improvement journey in the 21st Century?
This document discusses corrective and preventive action (CAPA) systems and how they are used to mitigate risk. It provides three key points:
1) CAPA systems use non-conformances, deviations, and potential problems to investigate quality issues, identify corrective and preventive actions, and track the implementation of these actions.
2) CAPA aims to define the risk level associated with quality events and ensure appropriate actions are taken based on risk level, from further investigation and corrective actions for high risks to no action for low risks.
3) Effective CAPA systems incorporate change control to evaluate and document any changes made as a result of corrective actions to avoid introducing new risks.
Lean Six Sigma applications in healthcare require an understanding of how the tools and methodologies translate to the people-intensive processes of patient care. Once applied, the possibilities are endless. Using real-world examples of the most common types of errors in clinical services, participants will learn how the DMAIC structure within Lean Six Sigma will lead them to solutions that will prevent future errors.
Over the Top Process Safety Lessons Related to Liquid LevelAlan Munn
This document discusses lessons related to liquid level measurement in process vessels and tanks. It notes that level instruments often provide inaccurate readings due to design flaws, installation errors, or lack of understanding about how they work. This can lead to overfilling vessels. It discusses reasons for inaccurate readings, including instruments being calibrated for the wrong fluid density or temperature. Levels in standpipes or bypass lines may differ from vessel levels. Plugged tapping points also cause false readings. Poor operator understanding of instruments and "normalization of deviance" contribute to safety issues. Management of change and human factors need more attention to address level measurement problems.
This document summarizes a presentation on common errors in tank design that lead to safety incidents. The key points are:
1) Fires and explosions at storage tanks continue regularly despite basic tank technology remaining unchanged, showing lessons from past incidents are not being applied. An overreliance on vendors and seeing tanks as commodities leads to insufficient engineering input into design.
2) Modifications especially pose challenges as design errors are often missed. The author provides examples where miscommunication with vendors, lack of clear specifications, and lowest-cost mindsets compromised safety.
3) Specific cases highlight issues like mistaking small "blast hatches" for internal explosion protection and poor inlet distributor design increasing static risks. Overall,
This document provides specifications for the CX series of total stations from Topcon, including:
1) Measurement ranges from 0.3 to 500m for the standard models and enhanced ranges for low-temperature and high-temperature models.
2) Angular measurement accuracy of 0.5-1 seconds and 1-5 seconds depending on the model.
3) Various distance measurement capabilities including reflectorless, mini prism, reflective sheet, and prism modes.
4) Features such as dual-axis compensation, IP66 dust and water resistance, and a 36 hour battery life.
5) Interface options including Bluetooth, USB, and internal memory storage.
This document discusses screening, including defining screening as applying tests to asymptomatic individuals to identify those at high risk of disease. It outlines objectives of screening like early disease detection. Characteristics of diseases suitable for screening include having a long pre-symptomatic phase and effective treatment existing. Screening tests should be reliable, acceptable, safe and low-cost. Sensitivity measures a test's ability to correctly identify those with disease, while specificity measures its ability to correctly identify those without disease. Screening criteria include the disease burden and test validity, reliability, costs and benefits.
This document discusses the top 5 Android-based phablets of 2013. It defines phablets as innovative devices with screen sizes between 5-7 inches that are not quite tablets or smartphones. The top 5 are listed as the Samsung Galaxy Note 3, LG G2, Samsung Galaxy Mega, Asus FonePad 7, and LG Optimus G Pro. Each device is summarized briefly, outlining its key specs like screen size, processor, storage, and camera details.
This document contains the resume of Analyn Rose M. Laranjo, who is seeking a position as a school teacher. She has a Bachelor's degree in Elementary Education from the University of Southeastern Philippines and has completed 6 internships as a pre-service teacher at various elementary schools. Her most recent work experience includes a clerk position at the local government of Maco from May to August 2015 and working as a teacher at D'moms Tutorial Center since October 2015. She has also attended several seminars and workshops on teaching methods and skills.
This document provides specifications for Sokkia's Series20 total station surveying instruments, including the SET220, SET320, SET520, and SET620 models. It summarizes their key features such as 30x magnification, dual-axis compensator, IP66 dust and water resistance, internal memory storage, and ability to measure distances up to 3,500 meters with prisms or 150 meters to reflective sheet targets. Rechargeable batteries provide up to 10 hours of continuous use from a single charge. Optional accessories include a wireless keyboard, CF card drive, and external battery.
5 social media tools to try in 2016, apart from hoot suiteweblinkindia1
The document discusses alternative social media management tools to HootSuite. It introduces 5 tools: Buffer, Tweetdeck, SumoRank, Sprout Social, and IFTTT. For each tool, it provides a brief description of what it is known for, which social media platforms it supports, its origins, and some of its core capabilities. The document recommends trying the free versions of these tools to see which is the best fit for managing your business's social media accounts.
Hazard and Operability Study (HAZOP) | Gaurav Singh RajputGaurav Singh Rajput
This document provides an overview of Hazard and Operability (HAZOP) studies. It begins with defining what a HAZOP study is, which is a systematic technique used to identify potential hazards and operating problems in industrial processes. The document then discusses the origins and development of HAZOP methodology. It provides details on the objectives, procedures, guidelines and key aspects of conducting a HAZOP study, including dividing the process into sections, using guide words to identify possible deviations, and documenting causes, consequences and recommended actions. Overall, the document serves as an introduction to HAZOP studies, covering their fundamental principles and approaches.
This document provides an overview of Hazard and Operability (HAZOP) studies. It defines HAZOP as a systematic technique used to identify potential hazards and operating problems in industrial processes. The document traces the origins and development of HAZOP studies since the 1960s. It describes the objective, methodology, and typical applications of HAZOP for improving safety and operability. Key aspects covered include identifying deviations from normal operating conditions, evaluating causes and consequences, and suggesting corrective actions.
This document provides guidelines for conducting Hazard and Operability (HAZOP) studies according to Saudi Aramco's procedures. It describes the basic concepts of HAZOP including identifying how a process may deviate from its design intent. The document outlines the typical steps to conduct a HAZOP study, including defining objectives and scope, assembling a multi-disciplinary team, conducting the study, and documenting results. It also provides guidance on applying HAZOP at different stages of a project from early design to existing operations.
The Hazard and Operability Study (HAZOP) is a structured and systematic assessment of a complex system, (such as process facility) in order to identify the hazards that can cause potential danger to Personnel, Equipment, Environment, as well as system operability.
iFluids Engineering is a leading provider of HAZOP study consulting services in India & have extensive experience working on HAZOP studies in India, Qatar, Oman, Tunisia, and many other countries
Europec 2016 - Chris Hopper - SPE 180176-MSChris Hopper
This document discusses project management approaches for oil and gas developments in an environment of sustained low oil prices. It notes that traditional linear project management systems have failed to deliver projects on time and budget over 70% of the time. These traditional approaches are not well-suited for complex projects with significant uncertainty. The document describes an alternative approach used in the 1990s that embraced uncertainty and allowed projects to accommodate change. It also discusses a recent North Sea project where the development plan was designed to accommodate a range of potential outcomes in order to gain project approval despite uncertainty. The document argues the industry needs approaches that produce resilient projects able to adapt to changing conditions rather than arbitrary cost cuts alone.
This document provides an overview and introduction to a HAZOP (Hazard and Operability Study) training workshop. It discusses the key drivers for process safety regulations like OSHA PSM, including several major industrial accidents. It then explains what a HAZOP study is, how it fits into Process Hazard Analysis requirements, and provides definitions and methodology descriptions for conducting a HAZOP. The document is intended to introduce participants to HAZOP and provide essential background information on regulatory frameworks and best practices for process safety management.
A Hazard and Operability (HAZOP) study is a systematic technique used to identify potential hazards and operability problems in processes. It involves a multidisciplinary team systematically examining a process or operation using guidewords to identify deviations from the design intent and hazards associated with those deviations. The document provides an overview of HAZOP studies, including their objectives, methodology, terminology, and examples of their application.
Productivity improvement in generation of so ps for oil & gas equipment manuf...QuEST Global
This white paper enables an SOP publisher to understand the advantages of employing an onsite project lead to accelerate the generation of a high quality SOP in Oil & Gas industry. A publisher can critically understand the success factor of such an engagement and the process of arriving at the new generation factor.
This document discusses conducting a Hazard and Operability (HAZOP) study. A HAZOP study is a systematic technique used to identify potential hazards and operating problems in a process. It involves examining process diagrams and considering how deviations from normal operating conditions could lead to hazardous situations. The document outlines the origins and development of HAZOP studies, their objectives, how and why they are used, and key aspects of conducting one such as focusing on specific nodes, parameters, and guide words to identify deviations, causes, consequences and actions.
Hazop Training - Intermediate Level Course iFluidsJohn Kingsley
The Fundamentals of HAZOP Study
A hazard and operability study (HAZOP) is a structured and systematic examination of a complex planned or existing process or operation in order to identify and evaluate problems that may represent risks to personnel or equipment. In this online training, you will be learning The Fundamentals of HAZOP Study.
What you will learn
HAZOP Study Stands for Hazard and Operability Study. Hazop is the structured brainstorming technique to identify Hazards involved in a chemical process plant. It is an important Industrial Safety tool. HAZOP study is carried out during the design stage of the process plant or during carrying out any modification in the existing plant. Live interactive sessions over the internet, combined with practical examples completed offline and shared via email to us. You will simply require a computer with a reliable internet connection, a headset with a high-quality microphone.
Course Content
What is a HAZOP Study?
Definition of basic terms
Risk matrix/ALARP principle
When to Perform a HAZOP Study
Different stages of Hazop study and relevant Data requirement
HAZOP STUDY - TEAM COMPOSITION
Generally accepted rules of HAZOP
Overall HAZOP Methodology
Layers of protection/Safeguard
Hierarchy of controls (with simple example)
HAZOP Study-Example
https://trainings.ifluids.com/
Successfully Achieving And Delivering ResultsThrough Rigorous Project Select...shawncarner
This document discusses the need for rigorous project prioritization tools and processes at Genentech and provides examples of project prioritization approaches used at different sites within Genentech. It highlights the benefits of standardized, transparent prioritization processes, including better use of resources, managing change capacity, and increased understanding and quantification of project impacts. Examples of prioritization tools and processes currently used at different sites are presented, along with next steps to further improve and standardize prioritization across sites.
This document summarizes key aspects of ISO20072, a standard for verifying the design of inhaler devices. It discusses topics like the Device Functionality Profile (DFP), how it relates to risk assessments and pharmaceutical testing, environmental testing conditions, verifying internal mechanisms, sample sizes for testing, and how to address non-DFP requirements. Some of the challenges discussed include linking device and pharmaceutical testing, maintaining tight environmental controls, verifying mechanisms not visible, and justifying excluding functions from testing. The document aims to provide practical guidance and perspectives on interpreting and applying the standard from the viewpoint of device developers.
The document discusses HAZOP (Hazard and Operability) studies and QRA (Qualitative Risk Analysis) studies conducted in process industries. It provides details on how HAZOP studies work, including forming a HAZOP team, identifying system elements and parameters, considering potential deviations, and identifying hazards. It also discusses QRA methodology which includes hazard identification, scenario selection, frequency and consequence estimation. The document emphasizes the importance of HAZOP and QRA studies in identifying risks and improving safety.
This document provides an overview of Hazard and Operability Studies (HAZOP). It discusses the importance and methodology of HAZOP analysis, including forming a team, identifying system elements and parameters, considering deviations, and identifying hazards. Keywords such as "no", "less", and "more" are used to systematically analyze each part of a process. The document also briefly discusses applications of HAZOP for design, operational, and procedural assessments and compares it to other risk analysis tools. An example HAZOP study for an acetylene production industry is referenced.
This document discusses applying the Hazard and Operability Study (HAZOP) methodology to analyze risks in an oil production unit. The following key points are made:
- A crude oil production unit was divided into sections and 71 potential risks were identified using the HAZOP methodology. The impacts of these risks were estimated.
- 47 recommendations were made to mitigate the detected risks based on the HAZOP analysis and defined safeguards.
- The study demonstrated the effectiveness of the HAZOP methodology in identifying potential hazards and evaluating their impacts for both new and existing oil production facilities.
Strategic Air Planning: Is the Time for a PAL Here?All4 Inc.
Mark Wenclawiak of All4 Inc. presents "Strategic Air Planning: Is the Time for a PAL Here?". The presentation discusses PAL permitting to support industrial growth, major New Source Review (NSR) issues, the importance of strategic planning, and why getting a PAL is particularly advantageous.
In plant visibility in process manu (final published)Alex Chatha
The document discusses best practices for in-plant visibility in process manufacturing based on research conducted by ARC Advisory Group, including a survey and interviews. The survey found that process manufacturers expect improved in-plant visibility to increase asset reliability and safety. Few have solid plans for achieving this. Interviews revealed a large range in maturity levels, from early stages to more advanced. ARC recommends manufacturers adopt three best practices used by more mature firms: address cultural impact, implement using cross-functional teams, and design early implementations for full scale-up.
HAZOP, or a Hazard and Operability Study, is a systematic way to identify possible hazards in a work process. In this approach, the process is broken down into steps, and every variation in work parameters is considered for each step, to see what could go wrong. HAZOP’s meticulous approach is commonly used with chemical production and piping systems, where miles of pipes and numerous containers can cause logistical headaches.
HAZOP and Hazard Analysis Systems
The document provides information about Hazard and Operability Studies (HAZOP). It describes the purpose and methodology of HAZOP studies, including identifying potential hazards, deviations, and operability issues. The document outlines when HAZOP studies should be conducted, who should be involved in the team, and the benefits of performing these studies, such as identifying safety and process improvements.
The document proposes updated definitions for technology, manufacturing, and services readiness levels based on lean product development principles. It argues the current definitions promote a flawed "build-test-fix" approach and presents alternative "Lean TRL", "Lean MRL", and "SRL" definitions grounded in robust design, design for six sigma, and lean principles. The updated levels aim to characterize and validate performance earlier to reduce costly late iterations compared to the conventional approach.
Similar to Common problems and recent trends with HAZOPs (20)