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CNS
CASE PRESENTATION
Dr hv Srinivas
• NAME : Prakash Chandra
• AGE : 57 yrs
• GENDER : male
• Occupation : grocery store owner
• HANDEDNESS : Right
• EDUCATION : primary school
• ADDRESS : orissa
HISTORY OF PRESENTING ILLNESS
Nov 2023:
The patient was apparently alright, then he started developing pain in both calf muscles, insidious in
onset, gradually progressive, more during night time a/w cramps. The patient got symptomatic
treatment in the local hospital with painkillers.
• Dec 2023 :
• The patient started noticing walking difficulty in both limbs, which was insidious in onset,
gradually progressive with no aggravating and relieving factors. He describes it as his left leg toe
touches the ground first followed by the heel when he walks. The patient was able to keep his
right leg normally.
• He also noticed difficulty in gripping the footwear with his left leg more then right leg, but he was
aware of slipping of footwear.
• He gives history of lower back ache with no diurnal variation and no radiation to the leg.
Jan 2024
• Patient gives h/o difficulty in getting up from the floor.
• Patient gives h/o tingling sensation in both lower limb ,insidious in onset , gradually progressive ,
initially started at big toe and other fingers progressed till mid ankle.
• h/o urinary disturbance in the form of increased frequency at night with no hesitancy or urgency.
• No h/o twitching of muscles, no h/o sensory and motor symptoms in upper limbs.
• no h/o fever and rashes ,joint pain
• No h/o cranial nerve involvement
• No h/o incoordination
• No h/o trauma
• No h/o weight loss
• no h/o feeling band like sensation over the abdomen
• No h/o difficulty in turning side to side in the bed & getting up from supine position
PAST HISTORY
• NO HISTORY OF SIMILAR COMPLAINTS IN THE PAST .
• Type 2 dm since 4 years on OHA , (uncontrolled)
FAMILY H/O :
not contributory
PERSONAL HISTORY
• Diet : mixed
• Appetite : good
• Sleep : undisturbed
• Bowel : normal
• Bladder : increase frequency
• Chronic smoker since 20 years, ethanol consumption 60 ml daily for 20 years
SUMMARY
• 57 year old male diabetic , h/o chronic smoking and ethanol consumption came with
asymmetrical onset of walking difficulty ( L>R) S/O distal lower limb weakness ( L>R) ,f/b proximal
lower limb weakness with sensory involvement in lower limb ( L>R) with increased urinary
frequency without upper limb involvement
GENERAL PHYSICAL EXAMINATION
• The patient is conscious, oriented & cooperative.
• Height – 162 cm
• Weight – 64 kg
• Pulse – 88 regular normal volume, character, condition, no radio radial or radio femoral delay.
• All Peripheral pulses felt
• BP – 120/70 mm Hg on right arm in sitting position
• RR- 16 cpm thoraco-abdominal type
• No pallor, icterus, cyanosis, clubbing, lymphadenopathy and edema.
• No raised JVP
• No neurocutaneous markers.
SYSTEMIC EXAMINATION
Central nervous system-
Higher mental functions
• Patient is conscious, oriented to time place and person.
• Registration –normal
• Attention and calculation- normal
• Recall – normal
• Language
naming ,repetition – Normal
3 step command – normal
• Reading –normal
• Writing – normal
• Copying - normal
Speech –spontaneous with intact comprehension,fluency.
Memory –immediate,recent ,remote –normal.
CRANIAL NERVE EXAMINATION
CRANIAL NERVES RIGHT LEFT
Olfactory N N
Optic
Visual acuity N N
Field of vision, colour vision N N
Fundoscopy
Occulomotor, trochlear, abducent
Pupils
Direct & indirect light reflex
Accommodation reflex
EOM
Nystagmus
3mm regular
Present
N
N
Absent
3mm regular
Present
N
N
Absent
Cranial nerves Right Left
Trigeminal nerve N N
Facial nerve N N
Vestibulocochlear nerve N N
Glossopharyngeal nerve N N
Vagus nerve N N
Spinal accessory nerve N N
Hypoglossal nerve N N
MOTOR SYSTEM
NUTRITION
MUSCLE BULK RIGHT LEFT
ARM 32 32
FOREARM 25 25
THIGH 42 40
LEG 27 27
TONE
RIGHT LEFT
UPPER LIMB –
ELBOW
WRIST
normal normal
LOWER LIMB-
KNEE
ANKLE
normal normal
POWER RIGHT LEFT
SHOULDER 5/5 5/5
FLEXION 5/5 5/5
EXTENSION 5/5 5/5
ADDUCTION 5/5 5/5
ABDUCTION 5/5 5/5
EXTERNAL ROTATION 5/5 5/5
INTERNAL ROTATION 5/5 5/5
ELBOW 5/5 5/5
FLEXION 5/5 5/5
EXTENSION 5/5 5/5
WRIST 5/5 5/5
FLEXION 5/5 5/5
EXTENSION 5/5 5/5
ULNAR DEVIATION 5/5 5/5
RADIAL DEVIATION 5/5 5/5
POWER RIGHT LEFT
HAND GRIP weak Weak
HIP JOINT 5/5 5/5
FLEXION 5/5 5/5
EXTENSION 5/5 5/5
ADDUCTION 5/5 5/5
ABDUCTION 5/5 5/5
EXTERNAL ROTATION 5/5 5/5
INTERNAL ROTATION 5/5 5/5
KNEE JOINT
FLEXION 5/5 5/5
EXTENSION 5/5 5/5
ANKLE JOINT
DORSIFLEXION 5/5 1/5
PLANTAR LEXION 5/5 5/5
SUBTALAR JOINT
INVERSION
EVERSION
5/5
5/5
2/5
5/5
DEEP TENDON REFLEXES RIGHT LEFT
BICEPS 3+ 3+
TICEPS 3+ 3+
SUPINATOR 3+ 3+
KNEE 2+ 2+
ANKLES 2+ 2+
SUPERFICIAL REFLEXES RIGHT LEFT
CORNEAL PRESENT PRESENT
CONJUNCTIVAL PRESENT PRESENT
ABDOMINAL-UPPER
MIDDLE
LOWER
PRESENT
PRESENT
PRESENT
PRESENT
PRESENT
PRESENT
PLANTAR FLEXOR EXTENSOR
ANAL REFLEX NOT DONE NOT DONE
COORDINATION
• UPPER LIMBS: NORMAL ON BOTH SIDES
• LOWER LIMBS : NORMAL
• NO CEREBELLAR SIGNS
• GAIT-LEFT FOOT DRAGGING
SENSORY SYSTEM
• SUPERFICIAL SENSATIONS
1. FINE TOUCH- DECREASED (20 %) ON LEFT ON LEFT DORSUM OF FOOT.ALL OTHER AREAS NORMAL.
2. PIN PRICK SENSATION-DECREASED (20%) ON LEFT DORSUM OF FOOT..ALL OTHER AREAS NORMAL.
• JOINT POSITION SENSE- INTACT
• DEEP SENSATIONS
1. PAIN- DECREASED( 20%) ON LEFT DORSUM OF FOOT ,TEMPERATURE- DECREASED 20%– ON LEFT ON LEFT
DORSUM OF FOOT
• No signs of meningeal irritation.
• OTHER SYSTEM EXAMINATION-
• CVS- S1S2 HEARD ,no murmur
• RS- B/L NVBS HEARD
• PER ABDOMEN- SOFT NON TENDER
DIAGNOSIS
• NEURODEFICIT-LEFT FOOT DROP(LMN) , BILATERAL SENSORY DEFICIT L/L
(L>R), LOWER LIMB WEAKNESS( DISTAL>PROXIMAL , LEFT>RIGHT),WITH UL
HYPER REFLEXIA(UMN)
• LOCALIZATION- L5-S1( RADICLE /PLEXUS ), AHC, LARGE FIBRE SENSORY N
• PATHOLOGICAL-COMPRESSIVE / INFLAMMATORY/NON INFLAMMATORY
• ETIOLOGY-DIABETES , ALS ?

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CNS case presentation for medicine postgraduates

  • 2. • NAME : Prakash Chandra • AGE : 57 yrs • GENDER : male • Occupation : grocery store owner • HANDEDNESS : Right • EDUCATION : primary school • ADDRESS : orissa
  • 3. HISTORY OF PRESENTING ILLNESS Nov 2023: The patient was apparently alright, then he started developing pain in both calf muscles, insidious in onset, gradually progressive, more during night time a/w cramps. The patient got symptomatic treatment in the local hospital with painkillers.
  • 4. • Dec 2023 : • The patient started noticing walking difficulty in both limbs, which was insidious in onset, gradually progressive with no aggravating and relieving factors. He describes it as his left leg toe touches the ground first followed by the heel when he walks. The patient was able to keep his right leg normally. • He also noticed difficulty in gripping the footwear with his left leg more then right leg, but he was aware of slipping of footwear. • He gives history of lower back ache with no diurnal variation and no radiation to the leg.
  • 5. Jan 2024 • Patient gives h/o difficulty in getting up from the floor. • Patient gives h/o tingling sensation in both lower limb ,insidious in onset , gradually progressive , initially started at big toe and other fingers progressed till mid ankle. • h/o urinary disturbance in the form of increased frequency at night with no hesitancy or urgency.
  • 6. • No h/o twitching of muscles, no h/o sensory and motor symptoms in upper limbs. • no h/o fever and rashes ,joint pain • No h/o cranial nerve involvement • No h/o incoordination • No h/o trauma • No h/o weight loss • no h/o feeling band like sensation over the abdomen • No h/o difficulty in turning side to side in the bed & getting up from supine position
  • 7. PAST HISTORY • NO HISTORY OF SIMILAR COMPLAINTS IN THE PAST . • Type 2 dm since 4 years on OHA , (uncontrolled) FAMILY H/O : not contributory
  • 8. PERSONAL HISTORY • Diet : mixed • Appetite : good • Sleep : undisturbed • Bowel : normal • Bladder : increase frequency • Chronic smoker since 20 years, ethanol consumption 60 ml daily for 20 years
  • 9. SUMMARY • 57 year old male diabetic , h/o chronic smoking and ethanol consumption came with asymmetrical onset of walking difficulty ( L>R) S/O distal lower limb weakness ( L>R) ,f/b proximal lower limb weakness with sensory involvement in lower limb ( L>R) with increased urinary frequency without upper limb involvement
  • 10. GENERAL PHYSICAL EXAMINATION • The patient is conscious, oriented & cooperative. • Height – 162 cm • Weight – 64 kg • Pulse – 88 regular normal volume, character, condition, no radio radial or radio femoral delay. • All Peripheral pulses felt • BP – 120/70 mm Hg on right arm in sitting position • RR- 16 cpm thoraco-abdominal type • No pallor, icterus, cyanosis, clubbing, lymphadenopathy and edema. • No raised JVP • No neurocutaneous markers.
  • 11. SYSTEMIC EXAMINATION Central nervous system- Higher mental functions • Patient is conscious, oriented to time place and person. • Registration –normal • Attention and calculation- normal • Recall – normal • Language naming ,repetition – Normal 3 step command – normal • Reading –normal • Writing – normal • Copying - normal Speech –spontaneous with intact comprehension,fluency. Memory –immediate,recent ,remote –normal.
  • 12. CRANIAL NERVE EXAMINATION CRANIAL NERVES RIGHT LEFT Olfactory N N Optic Visual acuity N N Field of vision, colour vision N N Fundoscopy Occulomotor, trochlear, abducent Pupils Direct & indirect light reflex Accommodation reflex EOM Nystagmus 3mm regular Present N N Absent 3mm regular Present N N Absent
  • 13. Cranial nerves Right Left Trigeminal nerve N N Facial nerve N N Vestibulocochlear nerve N N Glossopharyngeal nerve N N Vagus nerve N N Spinal accessory nerve N N Hypoglossal nerve N N
  • 15. NUTRITION MUSCLE BULK RIGHT LEFT ARM 32 32 FOREARM 25 25 THIGH 42 40 LEG 27 27
  • 16. TONE RIGHT LEFT UPPER LIMB – ELBOW WRIST normal normal LOWER LIMB- KNEE ANKLE normal normal
  • 17. POWER RIGHT LEFT SHOULDER 5/5 5/5 FLEXION 5/5 5/5 EXTENSION 5/5 5/5 ADDUCTION 5/5 5/5 ABDUCTION 5/5 5/5 EXTERNAL ROTATION 5/5 5/5 INTERNAL ROTATION 5/5 5/5 ELBOW 5/5 5/5 FLEXION 5/5 5/5 EXTENSION 5/5 5/5 WRIST 5/5 5/5 FLEXION 5/5 5/5 EXTENSION 5/5 5/5 ULNAR DEVIATION 5/5 5/5 RADIAL DEVIATION 5/5 5/5
  • 18. POWER RIGHT LEFT HAND GRIP weak Weak HIP JOINT 5/5 5/5 FLEXION 5/5 5/5 EXTENSION 5/5 5/5 ADDUCTION 5/5 5/5 ABDUCTION 5/5 5/5 EXTERNAL ROTATION 5/5 5/5 INTERNAL ROTATION 5/5 5/5 KNEE JOINT FLEXION 5/5 5/5 EXTENSION 5/5 5/5 ANKLE JOINT DORSIFLEXION 5/5 1/5 PLANTAR LEXION 5/5 5/5 SUBTALAR JOINT INVERSION EVERSION 5/5 5/5 2/5 5/5
  • 19. DEEP TENDON REFLEXES RIGHT LEFT BICEPS 3+ 3+ TICEPS 3+ 3+ SUPINATOR 3+ 3+ KNEE 2+ 2+ ANKLES 2+ 2+
  • 20. SUPERFICIAL REFLEXES RIGHT LEFT CORNEAL PRESENT PRESENT CONJUNCTIVAL PRESENT PRESENT ABDOMINAL-UPPER MIDDLE LOWER PRESENT PRESENT PRESENT PRESENT PRESENT PRESENT PLANTAR FLEXOR EXTENSOR ANAL REFLEX NOT DONE NOT DONE
  • 21. COORDINATION • UPPER LIMBS: NORMAL ON BOTH SIDES • LOWER LIMBS : NORMAL • NO CEREBELLAR SIGNS • GAIT-LEFT FOOT DRAGGING
  • 22. SENSORY SYSTEM • SUPERFICIAL SENSATIONS 1. FINE TOUCH- DECREASED (20 %) ON LEFT ON LEFT DORSUM OF FOOT.ALL OTHER AREAS NORMAL. 2. PIN PRICK SENSATION-DECREASED (20%) ON LEFT DORSUM OF FOOT..ALL OTHER AREAS NORMAL. • JOINT POSITION SENSE- INTACT • DEEP SENSATIONS 1. PAIN- DECREASED( 20%) ON LEFT DORSUM OF FOOT ,TEMPERATURE- DECREASED 20%– ON LEFT ON LEFT DORSUM OF FOOT
  • 23. • No signs of meningeal irritation. • OTHER SYSTEM EXAMINATION- • CVS- S1S2 HEARD ,no murmur • RS- B/L NVBS HEARD • PER ABDOMEN- SOFT NON TENDER
  • 24. DIAGNOSIS • NEURODEFICIT-LEFT FOOT DROP(LMN) , BILATERAL SENSORY DEFICIT L/L (L>R), LOWER LIMB WEAKNESS( DISTAL>PROXIMAL , LEFT>RIGHT),WITH UL HYPER REFLEXIA(UMN) • LOCALIZATION- L5-S1( RADICLE /PLEXUS ), AHC, LARGE FIBRE SENSORY N • PATHOLOGICAL-COMPRESSIVE / INFLAMMATORY/NON INFLAMMATORY • ETIOLOGY-DIABETES , ALS ?