This document provides information on clean air solutions for a pharmaceutical cleanroom upgrade project. It details the project requirements including the desired particle counts before and after different time periods, room size and classification. It also lists the recommended filter efficiencies and types for the supply, extract and AHU systems. Charts are shown comparing particle count reduction over time and providing energy performance details for the recommended filter media. The CREO software solutions are highlighted for assisting with cleanroom design and life cycle cost optimization.

1. C L E A N A I R S O L U T I O N S
THE CAMFIL FARR GROUP
CREO
Cleanroom Design & Energy Optimization
Clean air solutions

2. C L E A N A I R S O L U T I O N S
Original concept was to marry Clean with LCC
Requirements
HEPA Filter Units Mark X REQUIRED DATA CLEAN UP RATE
Design Company Jacobs Eng Supply Terminals X
Particle larger than 0.5um Particle/m 3 after 1 min 1.24 E+8
Design Engineer John O Connell Room access BIBO X
Particle/ft 3 after 1 min 3.52 E+6
Client Pfizer - France Plantroom BIBO
3.0 E+7 (Particle / m 3) Dirty air Particle/m 3 after 10 min 5.32 E+6
Project P3 Upgrade Quantity
8.5 E+5 (Particle/ft 3) Particle/ft 3 after 10 min 1.51 E+5
Camfil Pharmaseals 259
ISO Roomside Camsafes 81 1E+4(Part/s) Clean room cloths Particle/m 3 after 1 hour 3.02 E+3
Room Classifation
GMP C Plantroom Camsafes n/a Particle/ft 3 after 1 hour 8.57 E+1
Room Size 10 x 12 x 3.5 Filter Efficiencies Particle/m 3 in room at start 3.02 E+3 Particle/m 3 steady state 3.02 E+3
Supply HEPA H14 - EN1822 Particle/ft 3in room at start 8.57 E+1 Particle/ft 3 steady state 8.57 E+1
Air change per hour 25
Extract HEPA H13 - EN1822 Particles from process 3.02 E+2
Room Pressure 25 Pa
AHU Final Filter F9 - CEN779-2002 1.00E+10
1.00E+09
Leakage Rate 5%
1.00E+08
AHU Pre Filters F6 - CEN779 - 2002 1.00E+07
Cooling / Heating O.O5c 1.00E+06
AHU Pre Filters G4 - CEN779 - 2002 1.00E+05
1.00E+04
1.00E+03
H13 HEPA Filters F9 Bag G4 Panel 1.00E+02
Filter Filter % of the air
is dumped to the 1.00E+01
outside air 1 10m in 20m in 30 m in 60m m
Dampers
Outside Energy Performance Kw/h € 0.075 cent
air
S. C. U. Face Average Energy running cost
Filter Media pack
F6 Bag Filter velocity p.drop per filter / per year
45mm 0.45 m/s ?
H13 Supply
68mm 0.45 m/s ?
HEPA
100mm 0.45 m/s ?
Extract 22 sqm 2.5 m/s ?
Class A/B L.A.F.
HEPA 40 sqm 2.5 m/s ?
Grade D Grade C (10,000) Cleanroom Offices & other
(100,000) Areas non-classified areas 4.0 sqm 2.5 m/s ?
F9 Bag 6.5 sqm 2.5 m/s ?
H14 HEPA F9 Bag Filters G4 Panel Filters 9.4 sqm 2.5 m/s ?
Prepared by : Don Donovan
H13 HEPA F6 Bag Filters Return Air ?
4.0 sqm 2.5 m/s
Specification and Options ( Please feel free to Copy & Paste) F6 Bag 6.5 sqm 2.5 m/s ?
9.4 sqm 2.5 m/s ?
Terminal Housing Click here CEN 779 2002 Standard Click here
Roomside Camsafe Click here EN 1822 Standard Click here 1.0 sqm 2.5 m/s ?
G4 Panel
Plantroom Camsafe Click here 1.3 sqm 2.5 m/s ?
This program is to b e used as only an aid - b la, b la
HEPA & AHU Filters Click here
Concept DD & SOR November 2006 Paris
Clean air solutions

3. C L E A N A I R S O L U T I O N S
Clean air solutions

4. LCC calculation software
C L E A N A I R S O L U T I O N S
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Clean air solutions

5. CERO softwareI O N S
C L E A N
A I R S O L U T
– Cleanroom and Energy Optimization
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Clean air solutions

6. CREO worksheet pads RavailableT fromSmarketing
C L E A N A I S O L U I O N
Clean air solutions

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C L E A N A I R S O L U T I O N S
Clean air solutions

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C L E A N A I R S O L U T I O N S
Clean air solutions

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C L E A N A I R S O L U T I O N S
Clean air solutions

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C L E A N A I R S O L U T I O N S
Clean air solutions

11. CREO webinar & manual...www.camfilfarr.us...industries..
life science page C L E A N A I R S O L U T I O N S
Clean air solutions

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C L E A N A I R S O L U T I O N S
Clean air solutions

13. C L E A N A I R S O L U T I O N S
Clean air solutions