The document discusses the U.S. EPA's Goal 1 of achieving clean air and addressing global climate change. It covers several topics including criteria air pollutants, air toxics, indoor air quality, stratospheric ozone protection, greenhouse gases, and climate change. Progress has been made in reducing various air pollutants and their health impacts, though further reductions are still needed to fully protect public health. The EPA conducts research and provides tools and guidance to support the achievement of air quality standards and goals.