This document discusses laboratory waste management guidelines in Malaysia and internationally. It provides information on relevant regulations and standards in Malaysia from organizations like the Department of Environment and Ministry of Health. The types of laboratory wastes are described for both Malaysia and other countries. The document also outlines best practices for laboratory waste handling and disposal, including proper personal protective equipment, designated waste areas, and following standard operating procedures. International references and organizations on laboratory waste management are also provided.
Lynas malaysia public communication july 13 2009 doe presentationLynas Malaysia
This presentation was conducted by DOE back in July 2009. The deck details the approval process Lynas went through to receive approvals for the construction of LAMP.
Lynas malaysia public communication july 13 2009 doe presentationLynas Malaysia
This presentation was conducted by DOE back in July 2009. The deck details the approval process Lynas went through to receive approvals for the construction of LAMP.
Wayne State University Laboratory Safety TrainingElena Fracassa
This training addresses basic laboratory safety issues for WSU labs and is required annually for all laboratory faculty, staff, and students working with hazardous chemicals.
Topics covered:
Contents of the OSHA Lab Standard (29 CFR 1910.1450)
WSU Chemical Hygiene Plan
Physical and health hazards of chemicals
Safety equipment in the laboratory
Safe handling and storage of chemicals
Hazard Communication & Global Harmonization System of Classifying & Labeling Chemicals
Safety Data Sheets
Personal Protective Equipment
Explanation of EPA, MDEQ, and DOT regulations
Explanation of the WSU Emergency Contingency Plan
Lab responsibilities as a hazardous waste generators
Definitions of hazardous waste
Procedures for collection, labeling, storage and removal of waste
Responding to injuries, spills, fires, and other emergencies in the lab
Laboratory safety is dependent on a collaboration between safety personnel and the laboratory personnel conducting the research and sample analysis. It is important to understand the hazards and risk to determine the heirarchy of controls. In caertain instances, use of personal protective clothing and equipment may be best option to protect the worker from harm. This seminar presents the issues that are pertinent for safety professionals to consider when inspecting any laboratory and understanding the chemical process and equipment used in the analysis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Wayne State University Laboratory Safety TrainingElena Fracassa
This training addresses basic laboratory safety issues for WSU labs and is required annually for all laboratory faculty, staff, and students working with hazardous chemicals.
Topics covered:
Contents of the OSHA Lab Standard (29 CFR 1910.1450)
WSU Chemical Hygiene Plan
Physical and health hazards of chemicals
Safety equipment in the laboratory
Safe handling and storage of chemicals
Hazard Communication & Global Harmonization System of Classifying & Labeling Chemicals
Safety Data Sheets
Personal Protective Equipment
Explanation of EPA, MDEQ, and DOT regulations
Explanation of the WSU Emergency Contingency Plan
Lab responsibilities as a hazardous waste generators
Definitions of hazardous waste
Procedures for collection, labeling, storage and removal of waste
Responding to injuries, spills, fires, and other emergencies in the lab
Laboratory safety is dependent on a collaboration between safety personnel and the laboratory personnel conducting the research and sample analysis. It is important to understand the hazards and risk to determine the heirarchy of controls. In caertain instances, use of personal protective clothing and equipment may be best option to protect the worker from harm. This seminar presents the issues that are pertinent for safety professionals to consider when inspecting any laboratory and understanding the chemical process and equipment used in the analysis.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
1. LABORATORY WASTE MANAGEMENT IN MEDICAL / HEALTH
UNIVERSITY
CHEMISTRY
BACHELOR OF OCCUPATIONAL SAFETY & HEALTH (HONS)
INTERNAL ASSESSOR : MOHAMMAD ADAM ADMAN
NADIATUL ASSYIFA BINTI MUHAMAD MAZLAN
NORASIKIN BINTI SENEN
2. MALAYSIA
• Department of
Environment, Ministry of
Health
INTERNATIONAL
• Department of
Environmental Health and
Safety, United States of
America
3. MALAYSIA
• Environmental Quality (Scheduled
Wastes) Regulations 2005
• Occupational Safety and Health
(Classification, Packaging and Labeling of
Hazardous Chemicals) Regulations 1997.
• Occupational Safety and Health
(Prohibition of Use of Substance) Order
• 1999.
• Occupational Safety and Health (Use and
Standards of Exposure of
• Chemicals Hazardous to Health)
Regulations 2000.
INTERNATIONAL
• 1976 by the Federal
Resource Conservation
and Recovery Act
4. MALAYSIA
• The Act states that it is
the duty of every
employer and self-employed
person to
ensure as far as
practicable, to provide a
safe and healthy work
environment for all
workers.
INTERNATIONAL
• Act introduced the
concept that the generator
of a waste is responsible
for proper waste
management
5. MALAYSIA
• Clinical waste
• Radioactive waste
• Chemical waste
• Pressurized containers
• General waste
INTERNATIONAL
• Chemical waste
• Clinical and healthcare
waste
• Radioactive waste
• Liquid wastes
• Laboratory glass
6. MALAYSIA
• Pentas Flora
• Department of Chemistry, Malaysia
• Department of Environment
• Department of Occupational Safety and
Health Malaysia
• Jabatan Bomba dan Penyelamat
Malaysia
• Malaysian Industrial Hygiene Association
• Malaysian Nuclear Agency
• Malaysian Society of Occupational Safety
and Health
• Ministry of Health Malaysia
• National Institute of Occupational Safety
and Health
• SIRIM Berhad (Secretariat)
INTERNATIONAL
• Association of Public
Health Laboratories
• National Center for
Environmental Health
• Office of Research
Services, National
Institutes of Health
• Office of Safety, Health,
and Environment
7. MALAYSIA
• General Rules of Safety
• • Personal Hygiene
• • Housekeeping
• • Handling Glassware
• 2) Chemical Safety Guideline
• Chemical Disposal
• Chemical Storage
• Packaging of Chemical
• Labeling of Chemical
• 3) Personal Protective Equipment
(PPE)
• 4) Laboratories Environment
INTERNATIONAL
• Personal protective equipment to be
used
• Engineering controls such as fume
hoods or other safety equipment
• Work practice controls such as
designated areas or work restrictions
• Monitoring (if needed)
• Occupational Health requirements (if
needed)
• Training requirements
• Storage, cleanup and waste disposal
• Emergency procedures
8. MALAYSIA
• Kualiti Alam
• The Department of
Environment in Malaysia
INTERNATINAL
• The Environmental Health
and Safety Center
(EH&S)
• Environmental Protection
Authority
• Environmental Protection
Agency (USEPA)
9. MALAYSIA
• Clinical waste
EX: Human tissues/free-flowing
blood
• Related waste
EX: Chemical Waste
• Waste segregation
• Respiratory
hygiene/cough etiquette
INTERNATIONAL
• Biohazardous Waste
(Regulated Medical
Waste)
Ex :Biologically-cultured
stocks and plates, human
blood or tissues
• Animal Bedding Waste
• Patient Care Waste
Disposal
15. • Knowing the type of chemical waste product.
• Follow the safety procedure to deal with laboratory
waste.
• Let the professional person handle the laboratory waste.
• Dispose the laboratory waste at the right place as
instructed
16. Yes.In order to improved quality standardsof laboratory
waste,Malaysia has adopted adherence to the standarts
of Good Laboratory Practices(GLP) as a pre-requisite
requirement for all laboratories,both in public and private
sectors nationally to meet the international regulatory
government.
17. • Government and Associations /Societies /Boards/
Councils that also responsible for Laboratory Wastes
work together to find the solution to sustain the most
effective management of laboratory waste.
• Both universities,public and private nationally must
have good management of laboratory wastes.
• Students must follow the rules and Standards
Operating Procedures(S.O.P) especially in laboratory.
18. Yes.Because works range of Occupational Safety &
Health(OSH) also include way to handling the waste
laboratory management especially chemical hazardous
waste in industries so that even small accident can be
prevented.
21. A special thanks to our chemistry lecturer,Encik
Mohammad Adam Adman for his guide and his help in
finishing this assignment.we also wants to thanks our friend
for their help in giving us support and information that we
need in order to complete this assignment.Lastly,a special
thanks to our parents and family for their love and support
that encourage us to study and complete our task given in
time.