Charter & Code and the HR Strategy for Researchers – creating an excellent environment for excellent researchers - NUAS Conference, Stockholm, 12-14 August 2012
Presentation given at the NUAS Conference on Communication Challenges for Nordic Universities which took place in Stockholm on 12-14 August 2012.
For more details see http://www.webforum.com/nuasconference/web/page.aspx.
Charter & Code, the Human Resources Strategy for Researchers and related EU...Dagmar M. Meyer
Presentation given at the Berlin Workshop of the project IREER – Industrial Relations for EU Excellence in Research Sectors which took place on 15-16 May 2012.
For more details on the IREER project, please see http://ec.europa.eu/employment_social/defis/publigrant/public/publications/127/frame.
The HR Strategy as a driver for excellence - DRC annual meeting 2010, Novi Sa...Dagmar M. Meyer
Presentation given at the 26th Annual Meeting of the Danube Rectors' Conference which took place on 4-6 February 2010 in Novi Sad.
For more details on the meeting see http://www.drc.uns.ac.rs/index.html.
Charter & Code and the HR Strategy for Researchers in the European context - ...Dagmar M. Meyer
Presentation given at the Workshop “HRS4R – The Human Resources Strategy for Researchers” which was organised by the Conference of Italian University Rectors (CRUI) and took place in Rome on 28 March 2012.
Marie Skłodowska-Curie Actions (MSCA) in Horizon 2020SRTD _ II
MSCA Objective
Ensure the optimum development and dynamic use of Europe’s intellectual capital in order to generate new skills, knowledge and innovation
Charter & Code, the Human Resources Strategy for Researchers and related EU...Dagmar M. Meyer
Presentation given at the Berlin Workshop of the project IREER – Industrial Relations for EU Excellence in Research Sectors which took place on 15-16 May 2012.
For more details on the IREER project, please see http://ec.europa.eu/employment_social/defis/publigrant/public/publications/127/frame.
The HR Strategy as a driver for excellence - DRC annual meeting 2010, Novi Sa...Dagmar M. Meyer
Presentation given at the 26th Annual Meeting of the Danube Rectors' Conference which took place on 4-6 February 2010 in Novi Sad.
For more details on the meeting see http://www.drc.uns.ac.rs/index.html.
Charter & Code and the HR Strategy for Researchers in the European context - ...Dagmar M. Meyer
Presentation given at the Workshop “HRS4R – The Human Resources Strategy for Researchers” which was organised by the Conference of Italian University Rectors (CRUI) and took place in Rome on 28 March 2012.
Marie Skłodowska-Curie Actions (MSCA) in Horizon 2020SRTD _ II
MSCA Objective
Ensure the optimum development and dynamic use of Europe’s intellectual capital in order to generate new skills, knowledge and innovation
The HR Strategy – where are we now - 14th Symposium ENRC, 29 June 2010Dagmar M. Meyer
Presentation given at the 14th Symposium of the European Network on Research Careers (ENRC) which took place in Brussels on 29 June 2010.
For more details see http://www.dfg.de/en/research_funding/research_careers/enrc/enrc_14/index.html.
Charter & Code and HR Strategy - Background and State of Play - RCN Seminar O...Dagmar M. Meyer
Presentation given at the seminar "How to attract and retain excellent researchers?" that took place in Oslo on 19 January 2011. The seminar was organised by the Research Council of Norway together with the Association of Higher Education Institutions, Norway.
For more details see http://www.forskningsradet.no/en/Event/How_to_attract_and_retain_excellent_researchers/1253963126263?lang=en.
Joe Luca QPR2014 - Research training excellence in Australia: a good practice...Ian Green
Keynote address to the QPR2014 (Quality in Postgraduate Research) conference, Adelaide, South Australia, April 11, 2014, by Joe Luca, Edith Cowan University.
This study examines the relationship between policy and practice in the world of open education. It draws largely on the findings of other research projects and their openly licensed outputs (e.g. Creative Commons, POERUP) to map open education policies. In this presentation we will take the audience on a 'world tour' of OER policy, highlighting important case studies and scaffolding a participative discussion where members of the OER community can refine their understanding of the key issues. In describing the policy context for OER we provide a short historical review of relevant policy, including the Budapest OA Initiative (2002); the establishment of a Global OER Community (2005); the Cape Town Declaration (2007) and the Paris Declaration (2012). We then go on to look at each continent in turn and talk about the different kinds of policy climates, highlighting local and national case studies which merit particular interest. We pay particular attention to the USA, where there are many interesting policies at institutional, local and state levels (and where original research has been undertaken in collaboration with OER pilot participants).
This study examines the relationship between policy and practice in the world of open education. It draws largely on the findings of other research projects and their openly licensed outputs (e.g. Creative Commons, POERUP) to map open education policies. In this presentation we will take the audience on a 'world tour' of OER policy, highlighting important case studies and scaffolding a participative discussion where members of the OER community can refine their understanding of the key issues.
Co-presented with Sara Frank Bristow (Salient Research) at OER14 (http://oer14.org/)
Presentation of the state of play of university autonomy in Europe in 2017 based on 4 dimensions: organisational, financial, staffing and academic autonomy.
A strategic approach to scholarly research in South Africa - S Veldsman (ASSAf)Rhodes University Library
A Strategic Approach to Scholarly Research in South Africa presented by S Veldsman at the Open Access Symposium - Rhodes University Library on 21 October 2014.
What's in the research librarian's tool shed?Reed Elsevier
Presents an overview of the basic tools, indicators and skills used to support researchers in evaluating, managing and improving their research performance.
The HR Strategy – where are we now - 14th Symposium ENRC, 29 June 2010Dagmar M. Meyer
Presentation given at the 14th Symposium of the European Network on Research Careers (ENRC) which took place in Brussels on 29 June 2010.
For more details see http://www.dfg.de/en/research_funding/research_careers/enrc/enrc_14/index.html.
Charter & Code and HR Strategy - Background and State of Play - RCN Seminar O...Dagmar M. Meyer
Presentation given at the seminar "How to attract and retain excellent researchers?" that took place in Oslo on 19 January 2011. The seminar was organised by the Research Council of Norway together with the Association of Higher Education Institutions, Norway.
For more details see http://www.forskningsradet.no/en/Event/How_to_attract_and_retain_excellent_researchers/1253963126263?lang=en.
Joe Luca QPR2014 - Research training excellence in Australia: a good practice...Ian Green
Keynote address to the QPR2014 (Quality in Postgraduate Research) conference, Adelaide, South Australia, April 11, 2014, by Joe Luca, Edith Cowan University.
This study examines the relationship between policy and practice in the world of open education. It draws largely on the findings of other research projects and their openly licensed outputs (e.g. Creative Commons, POERUP) to map open education policies. In this presentation we will take the audience on a 'world tour' of OER policy, highlighting important case studies and scaffolding a participative discussion where members of the OER community can refine their understanding of the key issues. In describing the policy context for OER we provide a short historical review of relevant policy, including the Budapest OA Initiative (2002); the establishment of a Global OER Community (2005); the Cape Town Declaration (2007) and the Paris Declaration (2012). We then go on to look at each continent in turn and talk about the different kinds of policy climates, highlighting local and national case studies which merit particular interest. We pay particular attention to the USA, where there are many interesting policies at institutional, local and state levels (and where original research has been undertaken in collaboration with OER pilot participants).
This study examines the relationship between policy and practice in the world of open education. It draws largely on the findings of other research projects and their openly licensed outputs (e.g. Creative Commons, POERUP) to map open education policies. In this presentation we will take the audience on a 'world tour' of OER policy, highlighting important case studies and scaffolding a participative discussion where members of the OER community can refine their understanding of the key issues.
Co-presented with Sara Frank Bristow (Salient Research) at OER14 (http://oer14.org/)
Presentation of the state of play of university autonomy in Europe in 2017 based on 4 dimensions: organisational, financial, staffing and academic autonomy.
A strategic approach to scholarly research in South Africa - S Veldsman (ASSAf)Rhodes University Library
A Strategic Approach to Scholarly Research in South Africa presented by S Veldsman at the Open Access Symposium - Rhodes University Library on 21 October 2014.
What's in the research librarian's tool shed?Reed Elsevier
Presents an overview of the basic tools, indicators and skills used to support researchers in evaluating, managing and improving their research performance.
Similar to Charter & Code and the HR Strategy for Researchers – creating an excellent environment for excellent researchers - NUAS Conference, Stockholm, 12-14 August 2012
The European Charter & Code for Researchers in view of current EU policy deve...Dagmar M. Meyer
Presentation given at the conference “The European Charter for Researchers in Poland” which took place in Warsaw on 15 June 2011. The conference was organised by the Foundation for Polish Science (FNP).
Attractive researcher careers for mobile minds in partnership with Member Sta...Dagmar M. Meyer
Presentation given at the "Workshop on improving the mobility of researchers between Europe and BRIC countries" at the French Permanent Representation to the EU in Brussels which took place on 12 June 2012. The workshop had been organised by the Strategic Forum for International S&T Cooperation (SFIC) and the ERA Steering Group on Human Resources and Mobility (SGHRM).
For more information on the workshop see http://ec.europa.eu/research/iscp/index.cfm?pg=sfic (under 'Horizontal Workshops') and http://www.eurosfaire.prd.fr/news/consulter.php?id=6953.
Charter & Code and HR Strategy - Introduction to the Policy Context - Seminar...Dagmar M. Meyer
Presentation given as part of the Seminar “The 'Human Resources Strategy for Researchers' in a European context” that took place in Nicosia, Cyprus, on 24 March 2011. The seminar was organised by the Planning Bureau of the Government of the Republic of Cyprus in collaboartion with the Research Promotion Foundation.
Institutional support & HRS4R: How to involve and engage stakeholders and res...Lana Jerolimov
This is the 1st webinar in a series of webinars regarding promotion of The European Charter and Code for Researchers and the HRS4R (Human Resources Strategy for Researchers).
This webinar is organized as a part of the EURAXESS TOP IV project, in close collaboration with the European Commission representatives in charge of the HRS4R procedure. It is intended to serve as a support material for the already existing abundant content created by the European Commission. All webinars from this series will be later on available at the EURAXESS portal, as a supporting material for national networks and institutions in the HRS4R procedure. These webinars are envisaged as a ‘’hands-on’’ approach to complement the already existing material (guidelines, templates etc.).
Presenter: Mary Kate O’Regan, University College Cork
Topic: ''Institutional support & HRS4R: How to involve and engage stakeholders and researchers in the process''
The presentation provides an overview of:
1. Who are the stakeholders?
2. Advantages of HR Excellence in Research to your Organisation
3. Why seek Involvement in the process of HR Excellence in Research
4. Benefits of Involvement
5. How to engage stakeholders? What UCC did.
Mary O’Regan is the HR Research Manager in University College Cork IRELAND (UCC). There are 980 research staff in UCC. She knows and understands the research landscape and has worked with researchers on the ground for many years supporting all aspects of their work. Mary is the designated HR point of contact for research staff within University College Cork and has designed and developed many bespoke training and career development initiatives for research staff in UCC. Mary is also a lead assessor for the European Commission and also trains many future assessors for the Commission.
Mary has a Master’s in Government - Research Policy, (2014) University College Cork, Diploma in Paralegal Studies (1992) Philadelphia Institute for Legal Studies – USA, Post Graduate Diploma Computer Science (1987) University College Cork and BA English and Archaeology (1986) University College Cork. She lives in Carrigaline, Co. Cork, Ireland with her husband and daughter.
Charter & Code and HR Strategy - How does it work - Seminar on the HR Strateg...Dagmar M. Meyer
Presentation given as part of the Seminar “The 'Human Resources Strategy for Researchers' in a European context” that took place in Nicosia, Cyprus, on 24 March 2011. The seminar was organised by the Planning Bureau of the Government of the Republic of Cyprus in collaboartion with the Research Promotion Foundation.
V Rolfe STEM 2012 Employer Engagement in OER 12April2012Vivien Rolfe
Talk given by Viv to the annual UK STEM conference, Imperial College on working with external collaborators to produce OER. Part of the UKOER Phase 3 project at De Montfort University, http://www.biologycourses.co.uk
Research processes (partial) - Project BPM in higher education institutionsTomislav Rozman
What is HEI-UP?
HEI-UP (Improving Business Processes in Higher Education Institutions) is a European project focused on upgrading BPM in HE (higher education) institutions through a common managerial model and offering an e-learning course for HEI managers under the umbrella of the European Certification and Qualification Association (ECQA).
Why business processes?
Business process management (BPM) has been argued to be a more effective and efficient way of managing organizations than a traditional hierarchical management approach.
Today, the most successful universities are business-oriented. An efficient BPM builds up an ideal environment for achieving a high level of pedagogical, research and administrative staff, and above all, student satisfaction.
What's in there for you and your institution?
The HEI-UP project gives you the opportunity to:
● Learn from and contribute to the managerial model developed within the project
● Become more aware of internal managerial efficiency through the tools and support provided
● Successfully align your business processes with the demands and needs of your students and faculty and
● Have free access to the BPM framework developed in the HEI-UP project.
What is expected from you?
We believe in the potentials and creative spirit of professional communities, so we expect that you:
● Engage in conversation with academics and BPM practitioners by sharing
good practices and challenges you or your institution have in relation to BPM,
● Share your BPM related research findings and thus contribute to BPM research or just exchange research ideas with fellow researchers or simply
● Observe and try to get out something good for your institution.
Researcher Mobility and Careers - Update on EU Policy Initiatives - RCN Semin...Dagmar M. Meyer
Presentation given at the seminar "How to attract and retain excellent researchers?" that took place in Oslo on 19 January 2011. The seminar was organised by the Research Council of Norway together with the Association of Higher Education Institutions, Norway.
For more details see http://www.forskningsradet.no/en/Event/How_to_attract_and_retain_excellent_researchers/1253963126263?lang=en.
The Knowledge Exchange is a partnership of six national
organisations within Europe. As part of its ambition to make
Open Scholarship work, the Knowledge Exchange has developed
a Framework for Open Scholarship. This sets out the different
phases in the research life cycle against a variety of perspectives
that present barriers/challenges for Science/Scholarship to
be open, at the same time acknowledging that there are many
levels of stakeholders, reaching from individual researchers to
institutions to national governments. In this talk the presenters
will explain the partnership and share their recent report and
current work around Open Scholarship.
Chris Keene, Jisc
Bas Cordewener, Jisc/Knowledge Exchange
Datacenter event - PEDCA general presentation - esther van bergen - 15-09-14Karim Network
On September 15th, Green IT Amsterdam and Paris Region Entreprises invited you to join them in Paris and get some insight into European knowledge and expertise on datacenters, especially on the sustainability issues.
WE learned more about the PEDCA project and How to reorganize computer rooms and data centers in an energy efficient way !
Similar to Charter & Code and the HR Strategy for Researchers – creating an excellent environment for excellent researchers - NUAS Conference, Stockholm, 12-14 August 2012 (20)
Supporting the Transition towards Open Access: Putting the Researcher at the ...Dagmar M. Meyer
Presentation given at the conference "Academic Publishing in Europe 12: Publishing Ethics: Doing the Right Thing - Doing Things Right (APE 2017)", which took place in Berlin on 17-18 January 2017.
Abstract: The European Research Council (ERC) supports the principle of open access to research results as a fundamental part of its mission. It strongly endorses the policy that informs the OA 2020 initiative for the large-scale transition to open access. As an organization that is governed by scientists, the ERC considers it crucial that this transition take into account the important role of researchers in this context, be it as producers of knowledge, as actors in the review and publication process (within the established system or otherwise), or as users of other researchers’ output. The vast diversity of situations across different research communities makes this a complex and challenging task.
With this backdrop, we will first outline the ERC’s approach towards open access, highlighting some of the bottlenecks in the implementation. We will then discuss a number of initiatives that the ERC has engaged in to support the researchers it funds in opening up their results, and provide a glimpse of some ideas for the future.
NB: The presentation is also available on Zenodo (https://doi.org/10.5281/zenodo.570151).
ISMTE 2016 Breakout Session: Should You Consider Transitioning Your Journal t...Dagmar M. Meyer
Presentation given at the ISMTE European Conference 2016 which took place on 31 October - 1 November 2016 in Brussels, Belgium.
Abstract: In this interactive session the presenter together with the participants will investigate the question "Should you consider transitioning your journal to open access?" by looking at the motivations for considering a 'flip', the related challenges and opportunities, and specific issues to be addressed. Different approaches and scenarios will be presented.
Participants are invited to share their real-life experiences, to discuss success factors, risks and benefits related to a transition to open access.
The presentation is strongly inspired by the following review:
Solomon, David J., Mikael Laakso, and Bo-Christer Björk (authors). Peter Suber (editor). 2016. Converting Scholarly Journals to Open Access: A Review of Approaches and Experiences; available at http://nrs.harvard.edu/urn-3:HUL.InstRepos:27803834 in open access (CC BY)
NB: This presentation is also available on Zenodo (https://doi.org/10.5281/zenodo.570164)
Open Access at the ERC - Open Access and Open Data in H2020, Bonn, 10 Septemb...Dagmar M. Meyer
Presentation given at the event "Open Access und Open Data in Horizont 2020 - Sonderveranstaltung für Multiplikatorinnen und Multiplikatoren" which took place in Bonn on 10 September 2015. The event was organised by the German Horizon 2020 National Contact Point for Legal and Financial Matters.
Mobility and pensions - a personal case study - Bologna Seminar 'Penalized fo...Dagmar M. Meyer
Presentation given at the Bologna Seminar "Penalized for Being Mobile? National Pension Schemes as an Obstacle to Mobility for Researchers in the EHEA" that took place in Berlin on 12-13 June 2008.
HR Strategy - step 3 Commission Acknowledgement - CPU meeting, Paris, 24 June...Dagmar M. Meyer
Presentation given at the “Meeting on the HRS4R” organised by the Conférence des présidents d'université (CPU) in Paris on 24 June 2011 (slides originally prepared in June 2011 for a seminar of the European Commission's 'HR Strategy Group' in Dublin).
HR Strategy - summary steps 1-5 - CPU meeting, Paris, 24 June 2011Dagmar M. Meyer
Presentation given at the “Meeting on the HRS4R” organised by the Conférence des présidents d'université (CPU) in Paris on 24 June 2011 (slides originally prepared in June 2011 for a seminar of the European Commission's 'HR Strategy Group' in Dublin).
Multiple mobility - a success story (?) - Conference Young researchers in Eur...Dagmar M. Meyer
Presentation given in the session "Table-Ronde: Jeunes chercheurs en Europe, quelles carrières pour demain?" at the French EU Presidency Conference "Jeunes Chercheurs en Europe" which took place in Rennes on 20-21 novembre 2008.
More details on the conference can be found here: http://www.eurosfaire.prd.fr/yre08/Jeunes_Chercheurs_en_Europe_dossier_complet.pdf
http://www.eurosfaire.prd.fr/yre08/Jeunes_Chercheurs_en_Europe_dossier_complet_veng.pdf
http://www.eurosfaire.prd.fr/yre08/programme.php
Conference conclusions:
http://www.eua.be/fileadmin/user_upload/files/Newsletter_new/Conclusions_YRE2008_1_.pdf
Speak Up if you have something to say - Marie Curie Conference, Manchester, 1...Dagmar M. Meyer
Presentation given in the session "The Marie Curie Fellowship Association - Providing a European Voice to Mobile Researchers: Celebrating the MCFA's 10th Anniversary" at the Marie Curie Conference (MC2) that took place at the University of Manchester on 10-12 April 2006.
For more details on the conference see: http://www.jb.man.ac.uk/mc2/overview/index.html
Fostering attractive research and training conditions in European Universitie...Dagmar M. Meyer
Presentation given at the EU Presidency Conference “Modernizing European Universities” which took place on 6 November, 2007 at the Universidade Nova de Lisboa, Lisbon, Portugal.
More information on the conference: http://www.umic.pt/images/stories/mctes/Programme_MUEuropeFinal.pdf
The EURAXESS Portal - Focus on EURAXESS Rights - Seminar on the HR Strategy f...Dagmar M. Meyer
Presentation given as part of the Seminar “The 'Human Resources Strategy for Researchers' in a European context” that took place in Nicosia, Cyprus, on 24 March 2011. The seminar was organised by the Planning Bureau of the Government of the Republic of Cyprus in collaboartion with the Research Promotion Foundation.
Forschercharta & Einstellungskodex – Entwicklungen und Perspektiven - 7. GEW-...Dagmar M. Meyer
Präsentation, die ich im Rahmen der 7. GEW-Wissenschaftskonferenz "Aufstieg oder Ausstieg?" gehalten habe, die vom 9.-12. Oktober 2013 in Berlin-Müggelsee stattfand. NB: Meine Teilnahme an dieser Konferenz war als Privatperson, nicht als Vertreterin der EU Kommission.
Auf den zugehörigen Artikel "Europäische Forschercharta und Einstellungskodex – Entwicklungen und Perspektiven", der im Tagungsband zur Konferenz erschienen ist, kann über Zenodo zugegriffen werden: https://zenodo.org/record/14807
Open access to excellent science - EPFL, 24 October 2013Dagmar M. Meyer
Presentation given at the event "Open Access: Authors, publishers, investors and institutions for the dissemination of the scientific research's results" which was organised by the library of EPFL (École polytechnique fédérale de Lausanne) in the context of the Open Access Week 2013 on 24 October 2013.
More information: http://library2.epfl.ch/conference_open_access/eng
Open access at the ERC - Vienna conference, 4 June 2013Dagmar M. Meyer
Presentation given at the conference "Wer hat Angst vor Open Access? Informationen und Hintergründe zu Open Access in Horizon 2020" ("Who's afraid of Open Access? Information and background on Horizon 2020") in Vienna on 3 June 2013. The event was organised by the Austrian Research Promotion Agency (FFG) and the European Liaison Office of the German Research Organisations (KoWi).
Conference webpage: http://rp7.ffg.at/rp7_openaccess2013
Open access and the ERC - EARMA Conference, 3 July 2013Dagmar M. Meyer
Presentation given in the session on "Open Access in Horizon 2020 and national policies in the member states" at the 19th EARMA Annual Conference "Stairways to Excellence in Research Management and Administration" on 3 July 2013.
The conference was hosted by Vienna University of Technology, Austria. More information: http://www.earma.org/Vienna2013/?id=1183
Open Access to Publications and Research Data – the European Research Council...Dagmar M. Meyer
Presentation at the workshop "Open Access and Open Data in Horizon 2020" which took place at the University of Göttingen (Germany) on 29 October 2014.
More information: http://www.uni-goettingen.de/de/open-access-und-open-data-in-horizon-2020/3218.html?cid=25293
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Charter & Code and the HR Strategy for Researchers – creating an excellent environment for excellent researchers - NUAS Conference, Stockholm, 12-14 August 2012
1. Research and
Innovation
Charter & Code and
the HR Strategy for Researchers –
creating an excellent environment for
excellent researchers
Dr. Dagmar Meyer
European Commission
DG Research and Innovation
NUAS Conference on Communication
Challenges for Nordic Universities
Stockholm, 12-14 August 2012
2. Overview
• Policy background: from the Careers
Communication to the Charter & Code and the
European Partnership for Researchers
• The Human Resources Strategy for Researchers:
what it is and why you should be interested in it!
• State of play – call for 4th cohort of the
Institutional HR Strategy Group
• Links to Innovation Union and ERA Framework
• Related on-going policy initiatives and links to
"Horizon 2020"
3. Careers Communication
• COM Communication (2003) “Researchers in
the ERA: One profession, multiple careers”
“The present Communication … aims to analyse the
different elements which characterise the profession
and defines the various factors which condition the
development of researchers’ careers at European level,
namely:
• the role and nature of research training,
• the differences in recruitment methods,
• the contractual and budgetary dimension, and,
finally,
• the evaluation mechanisms and
• the progress perspectives within the career.”
4. Charter & Code
• COM Recommendation to Member States
(March 2005) on a “European Charter for
Researchers and Code of Conduct for their
Recruitment”
• based on broad stakeholder consultation process
• follow-up activities focusing on implementation
• Competitiveness Council (April 2005) invites
Member States to:
• “raise awareness of the Charter and the Code within
their own country, on a voluntary basis, engage
actively with employers, funding organisations
and researchers and other relevant parties on their
application…”
5. Charter & Code – what is it?
• Reference framework for rights and obligations
of researchers, their employers and funders:
Ethical & professional aspects, incl. research
freedom and accountability, non-discrimination,
evaluation/appraisal
Recruitment, incl. transparency of the process, judging
merit, recognition of value of mobility and of
qualifications
Working conditions & social security, incl. research
environment, stability of employment, gender issues,
career development, and representation in governance
Training, incl. supervision, continued professional
development and access to training
6. Charter & Code – state of play
• More than 450 individual endorsements from
35 countries, plus various International/European
organizations
• Representing more than 1200 individual
institutions, including universities, research
institutes, funding bodies, umbrella organisations
and professional associations
• Nordic Region:
Iceland, Norway: good number of individual
endorsements
Denmark, Finland, Sweden: only Rectors' Conferences
and very few other organisations, if any
Greenland, Faroe I., Åland I.: none
7. ERA Expert Group recommendations
• Expert Group report (2008) on “Realising a
single labour market for researchers”:
“Any organisation in receipt of public funds for
research which signed the C&C is required:
• to define and advertise a Human Resources Mission
Statement, in line with the C&C spirit, focusing on
the recruitment, career development and retirement
procedures of their respective researchers; (…)”
• Expert Group recommends creation of a
‘ERA – Researchers’ Human Resources
Label’
8. European Partnership for Researchers
• COM Communication (2008) “Better careers and
more mobility: a European partnership for
researchers”. Four main themes:
Open recruitment and portability of grants
Meeting the social security and supplementary pension
needs of mobile researchers
Providing attractive employment and working conditions
Enhancing the training, skills and experience of
researchers
• EPR implementation monitored by the Steering
Group Human Resources and Mobility (SGHRM)
9. HR Strategy for Researchers (HRS4R)
• Tool to support the implementation of Charter
& Code – launched 2008
Voluntary, based on self-assessment and mutual
learning
Open to all research organisations and funders
Flexible validation approach, recognizes the
variety of situations across institutions
More than 200 institutions already taking part
Aim: include all major public employers and
funders of researchers in Europe (critical mass,
spill-over effects)
10. HRS4R – how does it work?
• Implemented via 5-step voluntary programme:
• Internal gap analysis by institution, involving key
institutional stakeholders including researchers
• Development and publication of institutional HR
strategy for researchers and action plan in
response to gaps identified
• Acknowledgement of progress by
Commission (logo)
• Self-assessment of implementation
after at most two years
• External analysis after at most four years
11. Key success factors and benefits
• HR Strategy process should be firmly integrated in
overall institutional strategy
• Support by institutional leadership crucial
• Support by national and sectoral organisations (e.g.
national HRS4R working group coordinated by RCN)
• Process should help institutions to do what they should
do anyway, just better:
more efficiently
more effectively
with more impact
• Evidence suggests: better HR management leads to
better results
12. Example: UK implementation via
Concordat
• UK-wide process coordinated by VITAE, based on the
"UK Concordat to Support the Career Development of
Researchers"
• Includes on-going national evaluation and benchmarking
• Initial review of perceived benefits to UK organisations of
the HR Excellence in Research Award in April 2012 - six
major themes emerged (19 responses in total)
• Contribution to strategic goals (84%)
• Impetus for change (90%)
• Supporting internal processes (84%)
• Raising the status of researcher development (63%)
• Meeting researchers’ needs (74%)
• Attracting funding (37%)
13. HRS4R – state of play
• “Institutional HR Strategy Group” set up in 2009,
3 cohorts operational so far
• Call for 4th cohort has been launched
• 150 members: universities, research institutions,
funding bodies,…
• Various multipliers and stakeholder
representatives as members or observers
• 101 logos awarded so far (including 58 (!!) UK
institutions)
• NB: HR Strategy process not restricted to members of
HR Strategy Group
14. Organisations from Nordic Region
already involved
• Denmark:
• Univ. of Aarhus
• Copenhagen Business
School
• Finland:
• Aalto University
• Univ. of Eastern Finland
• Univ. of Jyväskylä
• Univ. of Turku
• Iceland:
• Univ. of Reykjavik
• Rannís – The Icelandic
Centre for Research
• Norway:
• Univ. of Bergen
• Univ. of Oslo
• Univ. of Stavanger
• Univ. of Tromsø
• Norwegian Univ. of Science
and Technology (NTNU)
• Research Council Norway
• Peace Research Institute
Oslo (PRIO)
• SINTEF
• Sweden, Greenland,
Faroe I., Åland I.:
• none so far
15. Call for 4th cohort of HR Strategy Group
• Open to organisations that employ or fund researchers;
also umbrella organisations or multipliers
• Deadline for expressions of interest: 28 September
2012
• Selection of approximately 50 new members: early
October
• First information meeting in Brussels: 29 October 2012
• First Mutual Learning Seminar (1½ days) March/April
2013 (travel & accommodation covered by Commission)
• Documentation available on EURAXESS Rights –
section on "HR Strategy for Researchers"
16. Innovation Union
• COM Communication (2010) “Europe 2020 Flagship
Initiative - Innovation Union”
• IU commitment #4: In 2012, COM will propose an ERA
framework and supporting measures to remove obstacles
to mobility and cross-border cooperation, addressing
among others:
- quality of doctoral training, attractive employment
conditions and gender balance in research careers;
- mobility of researchers across countries and sectors,
including through open recruitment in public research
institutions and comparable research career structures
and by facilitating the creation of European
supplementary pension funds.
17. ERA Framework
• Article 182(5) TFEU entitles the Union to adopt all
measures that it deems necessary to achieve the ERA,
including legislative option
• Broad Stakeholder Consultation confirmed urgent need
for action in key areas such as open recruitment,
portability of grants, training and career
development (including working conditions)
• ERA Communication adopted 17 July 2012, proposing a
basket of concrete measures
• Close cooperation with stakeholder organisations (e.g.
NordForsk) and Member States
• Systematic and transparent monitoring and follow-up –
possibly legislation if insufficient progress
18. ERA Communication of 17 July 2012
• Numerous references to Charter & Code and HRS4R:
Member States invited to create an enabling
framework for the implementation of the HRS4R
as described in final report by the SGHRM WG on HR
issues
Research stakeholders invited to implement open,
transparent and merit based recruitment in line
with Charter & Code, and to develop strategies to
support the career development of researchers in
line with the HRS4R
Commission will support the setting up of a European
accreditation mechanism for Charter & Code-based
HR management in universities and publicly-funded
research institutions
19. Related on-going policy initiatives
• “Principles for Innovative Doctoral Training”
(including adherence to principles of Charter & Code)
• “European Framework for Research Careers” to
provide researcher competency classification
independent of a particular career path or sector
• Support for the creation of “Pan-European Pension
Funds for Researchers” (pilot schemes) by
employers of researchers
• Assessment of implementation and impact of the
“Scientific Visa Package” (cooperation with DG
HOME)
• Euraxess – Researchers in Motion initiative
20. Links to "Horizon 2020"
• Horizon 2020 will enhance attractiveness of the
research profession and facilitate mobility in a
cross-cutting way
• Charter & Code references in Marie Curie Actions in
FP7 exemplary => continue good practice
• New: Specific action to support institutions
implementing ERA principles in innovative ways
=> including Charter & Code
• New: ERA Chairs to attract outstanding academics to
institutions with high potential => including support
for creating supportive and competitive research
environment
21. More information:
Visit the EURAXESS portal,
section “Rights”, at
http://ec.europa.eu/euraxess/rights
or contact us at
RTD-CHARTER@ec.europa.eu