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Challenges in Management of Colon 
Cancer 
F. Chite Asirwa, MB ChB. MD. 
Asst. Professor of Medicine 
Division of Hematology/Oncology 
Indiana University 
Email: fasirwa@iu.edu 
Director, AMPATH Oncology and Hematology @ MTRH & 
Beacon Health Services, Nairobi 
Visiting Faculty Moi University School Of Medicine 
Beacon Health Services 1
Disclosures 
No Conflict of Interest to disclose
Colorectal Cancer: By Decades
Stage IV CRC: 2005
Beacon Health Services 5
Multidisciplinary team 
• Colorectal Surgeon 
• Gastroenterologist 
• Genetic Counselor 
• Interventional Radiologist 
• Medical Oncologist 
• Pathologist 
• Radiologist 
• Palliative care 
• Oncology Nurse 
• Oncology Pharmacist 
• Medical Social Worker 
• Nutritionist 
• Primary Physician etc etc 
Beacon Health Services 6
Improved Staging
Number LN Evaluated and Recurrence
Other Interventions 
• Laparoscopic colectomy 
• Metastatectomy 
– Liver Mets 
– Lung Mets 
• Other Modalities 
– TACE 
– RFA 
– etc 
Beacon Health Services 9
10 Year Survivors Following Hepatic Metastasectomy
Beacon Health Services 11
KRAS and CRC treatment
Conclusions 
• Screening 
• Diagnostics/Pathology 
• Surgery 
• Chemotherapy and Biologic agents 
• Radiotherapy 
• Survivorship care 
• Palliative care 
• Colostomy bags/Patient support groups 
• Clinical Trials Beacon Health Services 13
Thanks to Novartis for facilitating my 
attendance to this KESHO conference. 
To All the attendees and Organizers 
Beacon Health Services 14

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Challenges in management of colon cancer by f. chite asirwa

  • 1. Challenges in Management of Colon Cancer F. Chite Asirwa, MB ChB. MD. Asst. Professor of Medicine Division of Hematology/Oncology Indiana University Email: fasirwa@iu.edu Director, AMPATH Oncology and Hematology @ MTRH & Beacon Health Services, Nairobi Visiting Faculty Moi University School Of Medicine Beacon Health Services 1
  • 2. Disclosures No Conflict of Interest to disclose
  • 6. Multidisciplinary team • Colorectal Surgeon • Gastroenterologist • Genetic Counselor • Interventional Radiologist • Medical Oncologist • Pathologist • Radiologist • Palliative care • Oncology Nurse • Oncology Pharmacist • Medical Social Worker • Nutritionist • Primary Physician etc etc Beacon Health Services 6
  • 8. Number LN Evaluated and Recurrence
  • 9. Other Interventions • Laparoscopic colectomy • Metastatectomy – Liver Mets – Lung Mets • Other Modalities – TACE – RFA – etc Beacon Health Services 9
  • 10. 10 Year Survivors Following Hepatic Metastasectomy
  • 12. KRAS and CRC treatment
  • 13. Conclusions • Screening • Diagnostics/Pathology • Surgery • Chemotherapy and Biologic agents • Radiotherapy • Survivorship care • Palliative care • Colostomy bags/Patient support groups • Clinical Trials Beacon Health Services 13
  • 14. Thanks to Novartis for facilitating my attendance to this KESHO conference. To All the attendees and Organizers Beacon Health Services 14