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Challenges And
                          Opportunities With
                           Bio- & Nanotech


                                Tim Harper
                                Cientifica Ltd


Monday, 10 January 2011
Challenges And
                          Opportunities With
                           Bio- & Nanotech


                                Tim Harper
                                Cientifica Ltd


Monday, 10 January 2011
Tim Harper

         • Engineer at European Space
               Agency
         • Serial Entrepreneur
         • Co Founder NanoSight
         • Chair / Chief Advisor of Several
               National Funding Bodies
         • World Economic Forum
               Emerging Technologies
               Council / Tech Pioneers


                                              2
Monday, 10 January 2011
Challenge 1
                          Communicating Technology




Monday, 10 January 2011
The Challenge
             of
        Communication
         A constant battle for the first ten
                years of nanotech




Monday, 10 January 2011
The Challenge of
                            Regulation
Monday, 10 January 2011
• After 10 years we have no sensible
                          regulation of nanotechnologies

                   • Most technologies develop faster than
                          regulators can catch up




Monday, 10 January 2011
Challenge II
                          Making Technology Relevant




Monday, 10 January 2011
“Anyone talking about trillion dollar markets,
                     thousands of start-ups and billions of dollars of
                     VC money is missing the point of
                     nanotechnology.

                     ...most of the effects will not be called nano, and
                     they will be off the radar of most nano pundits
                     & gurus"

                                - Tim Harper 2003

Monday, 10 January 2011
•       Banking crisis

                  •       International tensions

                  •       Failed States

                  •       Facebook

                  •
                  •
                  •
                  •
                  •       Emerging Technologies



Monday, 10 January 2011
•       Banking crisis

                  •       International tensions

                  •       Failed States            Technology ranks low
                                                    on the global agenda
                  •       Facebook

                  •                                Need to relate it to
                                                     the issues that
                  •
                                                     governments &
                  •                                business understand
                  •
                  •       Emerging Technologies



Monday, 10 January 2011
Challenge III
                          Provide Solutions to Global Risks




Monday, 10 January 2011
Medium   High   Low


Monday, 10 January 2011
Global Population Growth
                    11,000,000


                    10,250,000


                      9,500,000


                      8,750,000


                      8,000,000


                      7,250,000


                      6,500,000
                               2010   2015   2020   2025   2030   2035    2040   2045   2050

                                             Medium        High     Low


Monday, 10 January 2011
Population Pressure
                 World Average Income Per Capita
                               2007   2022
 2007 Population                                                                  2007 Expenditure
   Distribution                                                                      Per Capita

     30%                                                                                     1

                                                                                             0.9
     25%
                                                                                             0.8

                                                                                             0.7
     20%
                                                                                             0.6

     15%                                                                                     0.5

                                                                                             0.4
     10%
                                                                                             0.3

                                                                                             0.2
      5%
                                                                                             0.1

      0%                                                                                     0
                           0




                                 00




                                        00




                                               00




                                                       00




                                                               00




                                                                       00




                                                                             00




                                                                                        00
           0




                          00




                                 ,0




                                        ,0




                                               ,0




                                                       ,0




                                                               ,0




                                                                       ,0




                                                                             ,0




                                                                                       ,0
                      5,




                                10




                                       15




                                              20




                                                      25




                                                              30




                                                                      35




                                                                            40




                                                                                      45
                                       GDP per capita (in 2000 USD)

Monday, 10 January 2011
!
  Global	
  trends	
  in	
  population,	
  energy	
  demand	
  and	
  water	
  use.	
  	
  Population:	
  	
  United	
  Nations	
  (http://esa.un.org/unpd/wpp2008/,	
  accessed	
  7/27/10).	
  	
  Energy:	
  	
  International	
  Energy	
  
  Agency	
  (http://www.worldenergyoutlook.org/2009.asp,	
  accessed	
  7/27/10).	
  	
  Water:	
  	
  Organization	
  for	
  Economic	
  Cooperation	
  and	
  Development	
  (http://www.oecd.org/document/
  20/0,3343,en_21571361_43893445_44353044_1_1_1_1,00.html,	
  accessed	
  7/27/10).


Monday, 10 January 2011
Monday, 10 January 2011
Monday, 10 January 2011
Leading To Events Like This
                             15
Monday, 10 January 2011
The Impact of
                                    Technology

                  • The average lifetime of a company on the
                          Fortune 500 is less than 30 years
                  • Google is ten years old
                  • Facebook is valued at $50 billion after five
                          years!




Monday, 10 January 2011
Opportunity 1
                          Catch The Wave of Emerging Technologies




Monday, 10 January 2011
5000 Years of Science




                                    18
Monday, 10 January 2011
5000 Years of Science

                          • We have been observing
                            the world for 5000 years




                                                       18
Monday, 10 January 2011
5000 Years of Science

                          • We have been observing
                            the world for 5000 years

                          • Significantly changing it
                            for 100 years




                                                       18
Monday, 10 January 2011
5000 Years of Science

                          • We have been observing
                            the world for 5000 years

                          • Significantly changing it
                            for 100 years

                          • Understanding our
                            actions for 20 years




                                                       18
Monday, 10 January 2011
Control Over Materials

                Materials Have Always Been
                Vital to Humanity
           •    Clothing,
           •    Heating, hunting tools
           •    Coal, iron, oil, copper
           •    Semiconductors
           •    Satellites




                                             19

Monday, 10 January 2011
Materials Have Shaped
                          Our Culture
10,000 BC
                     1000 BC       0      1800                1900’s                    2000                2010




  Stone
 & Wood                   Iron   Cement   Steel             Polymers                       Synthetic Biology
                                                           Composites            Nanotechnology




                                          Adapted from Herrmann, W. Chem. Eng. Technol. 21(7), 549 (1998)
                                                                                                                   20

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                             1650   1950   2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                                    Semiconductors
                             1650    1950            2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies
    Complexity




                                          Biotechnology
                                    Semiconductors
                             1650    1950            2050   21

Monday, 10 January 2011
Science Enables New
                              Technologies




                                              Nanotechnologies
    Complexity




                                          Biotechnology
                                    Semiconductors
                             1650    1950            2050        21

Monday, 10 January 2011
Science Enables New
                              Technologies



                                                     Synthetic Biology
                                              Nanotechnologies
    Complexity




                                          Biotechnology
                                    Semiconductors
                             1650    1950                2050            21

Monday, 10 January 2011
Science Enables New
                              Technologies


                                                         Geoengineering?
                                                     Synthetic Biology
                                              Nanotechnologies
    Complexity




                                          Biotechnology
                                    Semiconductors
                             1650    1950                2050            21

Monday, 10 January 2011
Science Enables New
                              Technologies


                                                         Geoengineering?
                                                     Synthetic Biology
                                              Nanotechnologies
    Complexity




                                          Biotechnology




                                                                          Control
                                    Semiconductors
                             1650    1950                2050            21

Monday, 10 January 2011
Moving From Control Of
                     Materials to Control of
                             Things




                               22
Monday, 10 January 2011
Moving From Control Of
                     Materials to Control of
                             Things
                   Materials
              • Metals
              • Semiconductors
              • Food Processing
                          Passive
                                    22
Monday, 10 January 2011
Moving From Control Of
                     Materials to Control of
                             Things
                   Materials             Things
              • Metals                   • Crops
              • Semiconductors           • Cells
              • Food Processing          • The Planet?
                          Passive         Active
                                    22
Monday, 10 January 2011
10 Years of Nanotech




                                   23
Monday, 10 January 2011
10 Years of Nanotech
       Household Cleaners                               Sporting Equipment

                            Food             Displays   Drug Delivery
      Insulation
                        Sunscreen   Paints Water Treatment
                                                       Construction
                    Cosmetics     Lighting    Filtration
                                      Anti Corrosion Data Storage
                           Textiles
                                           Computer Memory
                 Coatings
       Catalysis        Tissue Engineering
                                              23
Monday, 10 January 2011
10 Years of Nanotech




                                   23
Monday, 10 January 2011
The Challenge for the
                             Next 10 Years

                  • Make technology relevant to global issues
                  • Communicate that technology is (in general)
                          something that improves our lives




Monday, 10 January 2011
Operating Theatre 1910
Monday, 10 January 2011
Monday, 10 January 2011
Opportunity II
                            Learn From Nature




Monday, 10 January 2011
How To Use Them?




                                 28
Monday, 10 January 2011
Understanding Nature




                                   29
Monday, 10 January 2011
A Top Down Approach




                              30
Monday, 10 January 2011
A Bottom Up Approach




                            31
Monday, 10 January 2011
By Copying This Trick

                     Reducing friction between container ships hull
                     & water could
                          • Save 1% of global oil consumption or
                          • 850,000 barrels per day


                                               32
Monday, 10 January 2011
An Old Trick For Textiles




                            33
Monday, 10 January 2011
Nanocomposite
                              Materials
               • Polymer + nanoparticle, nanofibre or clay
               • Increases strength & rigidity
               • Lowers weight
               • Much of value is in the formulation rather than
                     the filler




                                       34
Monday, 10 January 2011
Nanocomposite
                              Materials
               • Polymer + nanoparticle, nanofibre or clay
               • Increases strength & rigidity
               • Lowers weight
               • Much of value is in the formulation rather than
                     the filler


                          Abalone Shell - Nanoscale Engineering
                                           34
Monday, 10 January 2011
Opportunity III
                            Combining Technologies




Monday, 10 January 2011
Longest Published DNA Sequence




                          Synthetic Biology
                                                            Source: Rob Carlson synthesis.cc
                                                 36
Monday, 10 January 2011
A Lot Like Moore’s Law
                             37
Monday, 10 January 2011
• Most technologies are becoming like
                          Facebook

                   • What used to be done at Bell Labs or IBM
                          can be done by far smaller teams

                   • Access to information and simulation are
                          key drivers




Monday, 10 January 2011
Addressing the
                            Challenge




Monday, 10 January 2011
Addressing the
                                  Challenge
                    Sustained technology innovation is the only way
                    that the world has supported six billion people
                    and will continue to sustain 9 billion people by
                    2050.
                          ‣ WEF Global Agenda Council on Emerging
                           Technologies



Monday, 10 January 2011
The Challenge of
                          Sustained Innovation




Monday, 10 January 2011
The Challenge of
                           Sustained Innovation

                          We cannot take emerging technologies for
                          granted; great societies that failed to innovate
                          have collapsed in the past.




Monday, 10 January 2011
The Challenge of
                               Proactive Risk
                                Management
                          Risk management is not a passive process. The
                          21st century presents challenges in terms of
                          population, energy, food, water, climate and
                          health – a proactive technology-based
                          approach is essential to be able to monitor,
                          manage and mitigate these risks.



Monday, 10 January 2011
The Challenge of
                           Cooperation

                    Governments, chemical companies, farmers,
                    technology players, consumer product
                    companies, NGOs, and consumers need to work
                    together to realize the potential of a bio-based
                    sustainable society.




Monday, 10 January 2011
In The End...




                                43
Monday, 10 January 2011
In The End...

                  • Technology has lead every economic and social
                          advance for the last 10,000 years




                                               43
Monday, 10 January 2011
In The End...

                  • Technology has lead every economic and social
                          advance for the last 10,000 years
                  • It can create and clear up problems (e.g
                          Ozone layer depletion)




                                               43
Monday, 10 January 2011
In The End...

                  • Technology has lead every economic and social
                          advance for the last 10,000 years
                  • It can create and clear up problems (e.g
                          Ozone layer depletion)
                  • It is human nature to innovate

                                               43
Monday, 10 January 2011
Conclusions




                               44
Monday, 10 January 2011
Conclusions

                     Nanotechnologies and biosciences will be as
                     important to the 21st Century as oil, polymers
                     and semiconductors were to the 20th Century




                                           44
Monday, 10 January 2011
Conclusions

                     Nanotechnologies and biosciences will be as
                     important to the 21st Century as oil, polymers
                     and semiconductors were to the 20th Century
                     We have the tools, lets use them wisely




                                           44
Monday, 10 January 2011
tim.harper@cientifica.com
                          Twitter: @tim_harper




Monday, 10 January 2011

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Challenges And Opportunities With Bio And Nanotech

  • 1. Challenges And Opportunities With Bio- & Nanotech Tim Harper Cientifica Ltd Monday, 10 January 2011
  • 2. Challenges And Opportunities With Bio- & Nanotech Tim Harper Cientifica Ltd Monday, 10 January 2011
  • 3. Tim Harper • Engineer at European Space Agency • Serial Entrepreneur • Co Founder NanoSight • Chair / Chief Advisor of Several National Funding Bodies • World Economic Forum Emerging Technologies Council / Tech Pioneers 2 Monday, 10 January 2011
  • 4. Challenge 1 Communicating Technology Monday, 10 January 2011
  • 5. The Challenge of Communication A constant battle for the first ten years of nanotech Monday, 10 January 2011
  • 6. The Challenge of Regulation Monday, 10 January 2011
  • 7. • After 10 years we have no sensible regulation of nanotechnologies • Most technologies develop faster than regulators can catch up Monday, 10 January 2011
  • 8. Challenge II Making Technology Relevant Monday, 10 January 2011
  • 9. “Anyone talking about trillion dollar markets, thousands of start-ups and billions of dollars of VC money is missing the point of nanotechnology. ...most of the effects will not be called nano, and they will be off the radar of most nano pundits & gurus" - Tim Harper 2003 Monday, 10 January 2011
  • 10. Banking crisis • International tensions • Failed States • Facebook • • • • • Emerging Technologies Monday, 10 January 2011
  • 11. Banking crisis • International tensions • Failed States Technology ranks low on the global agenda • Facebook • Need to relate it to the issues that • governments & • business understand • • Emerging Technologies Monday, 10 January 2011
  • 12. Challenge III Provide Solutions to Global Risks Monday, 10 January 2011
  • 13. Medium High Low Monday, 10 January 2011
  • 14. Global Population Growth 11,000,000 10,250,000 9,500,000 8,750,000 8,000,000 7,250,000 6,500,000 2010 2015 2020 2025 2030 2035 2040 2045 2050 Medium High Low Monday, 10 January 2011
  • 15. Population Pressure World Average Income Per Capita 2007 2022 2007 Population 2007 Expenditure Distribution Per Capita 30% 1 0.9 25% 0.8 0.7 20% 0.6 15% 0.5 0.4 10% 0.3 0.2 5% 0.1 0% 0 0 00 00 00 00 00 00 00 00 0 00 ,0 ,0 ,0 ,0 ,0 ,0 ,0 ,0 5, 10 15 20 25 30 35 40 45 GDP per capita (in 2000 USD) Monday, 10 January 2011
  • 16. ! Global  trends  in  population,  energy  demand  and  water  use.    Population:    United  Nations  (http://esa.un.org/unpd/wpp2008/,  accessed  7/27/10).    Energy:    International  Energy   Agency  (http://www.worldenergyoutlook.org/2009.asp,  accessed  7/27/10).    Water:    Organization  for  Economic  Cooperation  and  Development  (http://www.oecd.org/document/ 20/0,3343,en_21571361_43893445_44353044_1_1_1_1,00.html,  accessed  7/27/10). Monday, 10 January 2011
  • 19. Leading To Events Like This 15 Monday, 10 January 2011
  • 20. The Impact of Technology • The average lifetime of a company on the Fortune 500 is less than 30 years • Google is ten years old • Facebook is valued at $50 billion after five years! Monday, 10 January 2011
  • 21. Opportunity 1 Catch The Wave of Emerging Technologies Monday, 10 January 2011
  • 22. 5000 Years of Science 18 Monday, 10 January 2011
  • 23. 5000 Years of Science • We have been observing the world for 5000 years 18 Monday, 10 January 2011
  • 24. 5000 Years of Science • We have been observing the world for 5000 years • Significantly changing it for 100 years 18 Monday, 10 January 2011
  • 25. 5000 Years of Science • We have been observing the world for 5000 years • Significantly changing it for 100 years • Understanding our actions for 20 years 18 Monday, 10 January 2011
  • 26. Control Over Materials Materials Have Always Been Vital to Humanity • Clothing, • Heating, hunting tools • Coal, iron, oil, copper • Semiconductors • Satellites 19 Monday, 10 January 2011
  • 27. Materials Have Shaped Our Culture 10,000 BC 1000 BC 0 1800 1900’s 2000 2010 Stone & Wood Iron Cement Steel Polymers Synthetic Biology Composites Nanotechnology Adapted from Herrmann, W. Chem. Eng. Technol. 21(7), 549 (1998) 20 Monday, 10 January 2011
  • 28. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 29. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 30. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 31. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 32. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 33. Science Enables New Technologies Complexity 1650 1950 2050 21 Monday, 10 January 2011
  • 34. Science Enables New Technologies Complexity Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 35. Science Enables New Technologies Complexity Biotechnology Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 36. Science Enables New Technologies Nanotechnologies Complexity Biotechnology Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 37. Science Enables New Technologies Synthetic Biology Nanotechnologies Complexity Biotechnology Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 38. Science Enables New Technologies Geoengineering? Synthetic Biology Nanotechnologies Complexity Biotechnology Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 39. Science Enables New Technologies Geoengineering? Synthetic Biology Nanotechnologies Complexity Biotechnology Control Semiconductors 1650 1950 2050 21 Monday, 10 January 2011
  • 40. Moving From Control Of Materials to Control of Things 22 Monday, 10 January 2011
  • 41. Moving From Control Of Materials to Control of Things Materials • Metals • Semiconductors • Food Processing Passive 22 Monday, 10 January 2011
  • 42. Moving From Control Of Materials to Control of Things Materials Things • Metals • Crops • Semiconductors • Cells • Food Processing • The Planet? Passive Active 22 Monday, 10 January 2011
  • 43. 10 Years of Nanotech 23 Monday, 10 January 2011
  • 44. 10 Years of Nanotech Household Cleaners Sporting Equipment Food Displays Drug Delivery Insulation Sunscreen Paints Water Treatment Construction Cosmetics Lighting Filtration Anti Corrosion Data Storage Textiles Computer Memory Coatings Catalysis Tissue Engineering 23 Monday, 10 January 2011
  • 45. 10 Years of Nanotech 23 Monday, 10 January 2011
  • 46. The Challenge for the Next 10 Years • Make technology relevant to global issues • Communicate that technology is (in general) something that improves our lives Monday, 10 January 2011
  • 49. Opportunity II Learn From Nature Monday, 10 January 2011
  • 50. How To Use Them? 28 Monday, 10 January 2011
  • 51. Understanding Nature 29 Monday, 10 January 2011
  • 52. A Top Down Approach 30 Monday, 10 January 2011
  • 53. A Bottom Up Approach 31 Monday, 10 January 2011
  • 54. By Copying This Trick Reducing friction between container ships hull & water could • Save 1% of global oil consumption or • 850,000 barrels per day 32 Monday, 10 January 2011
  • 55. An Old Trick For Textiles 33 Monday, 10 January 2011
  • 56. Nanocomposite Materials • Polymer + nanoparticle, nanofibre or clay • Increases strength & rigidity • Lowers weight • Much of value is in the formulation rather than the filler 34 Monday, 10 January 2011
  • 57. Nanocomposite Materials • Polymer + nanoparticle, nanofibre or clay • Increases strength & rigidity • Lowers weight • Much of value is in the formulation rather than the filler Abalone Shell - Nanoscale Engineering 34 Monday, 10 January 2011
  • 58. Opportunity III Combining Technologies Monday, 10 January 2011
  • 59. Longest Published DNA Sequence Synthetic Biology Source: Rob Carlson synthesis.cc 36 Monday, 10 January 2011
  • 60. A Lot Like Moore’s Law 37 Monday, 10 January 2011
  • 61. • Most technologies are becoming like Facebook • What used to be done at Bell Labs or IBM can be done by far smaller teams • Access to information and simulation are key drivers Monday, 10 January 2011
  • 62. Addressing the Challenge Monday, 10 January 2011
  • 63. Addressing the Challenge Sustained technology innovation is the only way that the world has supported six billion people and will continue to sustain 9 billion people by 2050. ‣ WEF Global Agenda Council on Emerging Technologies Monday, 10 January 2011
  • 64. The Challenge of Sustained Innovation Monday, 10 January 2011
  • 65. The Challenge of Sustained Innovation We cannot take emerging technologies for granted; great societies that failed to innovate have collapsed in the past. Monday, 10 January 2011
  • 66. The Challenge of Proactive Risk Management Risk management is not a passive process. The 21st century presents challenges in terms of population, energy, food, water, climate and health – a proactive technology-based approach is essential to be able to monitor, manage and mitigate these risks. Monday, 10 January 2011
  • 67. The Challenge of Cooperation Governments, chemical companies, farmers, technology players, consumer product companies, NGOs, and consumers need to work together to realize the potential of a bio-based sustainable society. Monday, 10 January 2011
  • 68. In The End... 43 Monday, 10 January 2011
  • 69. In The End... • Technology has lead every economic and social advance for the last 10,000 years 43 Monday, 10 January 2011
  • 70. In The End... • Technology has lead every economic and social advance for the last 10,000 years • It can create and clear up problems (e.g Ozone layer depletion) 43 Monday, 10 January 2011
  • 71. In The End... • Technology has lead every economic and social advance for the last 10,000 years • It can create and clear up problems (e.g Ozone layer depletion) • It is human nature to innovate 43 Monday, 10 January 2011
  • 72. Conclusions 44 Monday, 10 January 2011
  • 73. Conclusions Nanotechnologies and biosciences will be as important to the 21st Century as oil, polymers and semiconductors were to the 20th Century 44 Monday, 10 January 2011
  • 74. Conclusions Nanotechnologies and biosciences will be as important to the 21st Century as oil, polymers and semiconductors were to the 20th Century We have the tools, lets use them wisely 44 Monday, 10 January 2011
  • 75. tim.harper@cientifica.com Twitter: @tim_harper Monday, 10 January 2011