This document describes how cells make up tissues, tissues make up organs, and organs work together in organ systems to form living organisms. It provides the example of how the thigh bone is composed of different tissues like cartilage and tendons, which are themselves made up of cells. The document includes an activity where students investigate chicken wings to identify different tissues and organs. It also discusses how Antonie van Leeuwenhoek first observed single-celled microorganisms using early microscopes.