Cellular biology, also known as cell biology, is the branch of biology that focuses on the study of cells - the basic structural, functional, and biological units of all living organisms. Cellular biologists explore various aspects of cells, including their structure, organization, metabolism, communication, and reproduction. They investigate how cells interact with each other and their environment, and how these interactions contribute to the overall function and behavior of multicellular organisms. Cellular biology plays a fundamental role in understanding life processes at the molecular and cellular levels, providing insights into the mechanisms underlying development, growth, health, and disease.

1. STEM CELLS :
CELL-BASED
THERAPY
DONE BY
CHANDA BHAVANA
111722516004

2. INTRODUCTION
● Stem Cells are cells that can both. Self-renew and also give rise to differentiated
progeny. They are probably present at all stages of development and in all tissues.
There is a gradient in their ability to give rise to diverse cell types (plasticity), from
pluripotent stem cells that can potentially produce germ-line and all somatic cell
types of ar organism, through to stem cells that are more restricted in their
differentiation potential and that multipotent. Are oligopotent a unipotent
● Pluripotent Embryonic stem Cells: derived from the early embryo, These are a
stage in development at which sells. Naturally are still sun specialized. Later, as
tissues. In development, cells become more and more form specialized, but some
stem cells are retained in fitus and in adults. They regenerate epithelial are needed
to tissue. Example: Blood, skin, intestinal cells have limited lifespan and are
replaced regularly by new sells produced by differentiation used in from tissue
Embryonic stem repair stem Cells ,stem cells also used in tissue repair

4. Embryonic Stem Cells:
cells of inner be isolated cells mass of a blastocyst can and cultured to generate embryonic stem
(ES) cell lines. ES well lines have clear advantage of cell therapy because they can grown
comparatively readily in culture and be propagated indefinitely and give rise to call lineages.
Different ES cells shows different variations with potential for differentiation.
Adult stem Cells (ASCs):
They are multipotent cells that are found in various tissues throughout body. Also called. Somatic
stem cells, they can be found in both juvenile and adult animals and humans.
ASC Can be found through the body most common. are bone marrow and adipose tissue
he lineage retricted. Terms of to ASC differentiation potential

5. Fetal stem Cell (FSC):
● They are multipotent cells located in fetal tissues. Depending on tissues they are capable
of generating.

6. Stem cell therapy
● In stem all therapy, a pioneering approach regenerative medicine, leverages. Ability of stem cells
The unique to repair and regenerate. Diverse tissues in body. Regeneration through immune
regulation and inflammation reduction.
● Repair Therapy harnesses the body’s degenerate. It’s a own well to key area of medical research.
With potential to significantly improve patient health outcomes.
● Stem Cell therapy works by utilizing the self-renewal immunomodulatory, anti-inflammatory.
Signalling and differentiation properties of stem cells to influence positive change within body
STEM CELLS ADMINISTRATION:
Stem cells car he administered in various IV Stem Cell Therapy, stem cell injections etc..
 Stem cell IV therapy:
stem cell Intravenous Infusions, involve administering substances directly into patient
bloodstream The infusion delivers Mesenchymal stem cells known for regenerative and
immunomodulatory properties. Directly to patient. This approach is tailored express capabilitie
like repairing damaged neural tissues, modulating immune system aiming therapeutics

7. Stem cell injections:
Stem cells injections, a form of regenerative medicine utilize unique properties of stem
cells to repair damaged or diseased tissues. In body there injections been applied in
treatment of various medical conditions.

8. HISTORY

9. PROCEDURE

10. Stem Cells Uses (Applications):
• Tissue regeneration and Repair:
tem cells can be used to replace damaged lost sells due to injury, disease or aging. By
differentiating into specialized cells, they facilitate the restoration of function in
affected tissues or organs.
Eg: Repairing damaged heart tissue after attack, regenerating cartilage in
osteoarthritis, and treating spinal cord injuries.
• Drug Discovery and testing:
stem cells can be utilized to create in-vitro models of human tissues. Enabling
researchers to test the safety and efficacy of new drugs and therapies. This
approach reduces need for animal testing and provide more accurate insights
potential drug interactions with human cells

11. Into Disease modelling:
Stem cells are con be used to generate disease-specific cell lines, enabling
researchers to study disease progression identify potential therapeutic targets. This
approach aids in understanding the underlying mechanisms of various genetic,
neurological and degenerative disorders.
Gene therapy and genetic editing:
stem cells can be genetically modified to correct mutations responsible for inherited
diseases. Techniques such as edit specific genes. CRISPR-Cas9 allow researchers to in
stern well, which can. Reintroduced into patient’s body to restore normal cellular
function.
•Immunotherapy
stem cells can play a role in modulating the immune system, making them valuable in
treating autoimmune diseases and preventing transplant rejection. Mesenchymal stem
cells. Immune-modulatory and anti- which man have demonstrated inflammatory
properties be harnessed for therapeutic purposes as in conditions such. Arthritis &
groft. –versus multiple sclerosis, rheumatoid host disease.

12. Personalized Medicine:
Stem cells ran be used to develop patient specific therapies, tailoring unique treatments
to on individual unique genetic makeup and disease progression.
DISEASES TREATED BY STEM CELLS:
● Stem cell research is rapidly evolving field with potential to revolutionize the treatment
many diseases. The potential applications cells span a wide stem of range of medical
conditions.
● Leukaemia and Lymphoma.
● Sickle Cell Anaemia
● Parkinson’s Disease.
● Spinal Cord Injuries.
● Type-1 Diabetes.
● Stroke
● Rheumatoid Arthritis. multiple Sclerosis.
● ALS (Amyotrophic Lateral sclerosis) Alzheimer’s Disease.
Osteoarthritis. Crohn’s Disease.
● Severe Burns.
● Corneal Disease.

13. Thank you.