This document summarizes the key determinants of blood pressure. It discusses how systolic and diastolic blood pressure have different determinants, with examples like how strenuous exercise increases systolic blood pressure but may decrease diastolic blood pressure. The main determinants listed are cardiac output, arterial compliance, pulse pressure transmission, vascular distensibility, and delayed compliance of vessels. Cardiac output is a major factor as it is determined by heart rate and stroke volume. Arterial compliance impacts how much pressure rises for a given stroke volume. Pulse pressure transmission and vascular distensibility also influence blood pressure.