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- 22. Drugs associated with Stevens-Johnson syndrome and TEN Adapted from Roujeau, JC, Stern, RS, N Engl J Med 1994; 331:1272. Ampicillin Amoxicillin Amithiozone (anti-tubuculosis agent) Allopurinol Piroxicam Phenylbutazone Barbituates Carbamazepine Hydantoins Trimethoprim-sulfamethoxazole Sulfasalazine Sulfadiazine Sulfadoxine More Frequently Thiabendazole Naproxen Ketoprofen Ibuprofen Sulindac Diclofenac Tiaprofenic acid Tenoxicam Fenbufen Ethambutol Rifampin Vancomycin Fluoroquinolone Cephalosporin Less Frequently