This document contains questions about Roche's acquisition of Genentech shares: 1) Roche is seeking the remaining 44% of Genentech shares to gain full ownership of the company. 2) Owning 100% would give Roche full control and synergies, but risks include losing a public listing and takeover premium. 3) As majority shareholder, Roche must protect minority shareholders' interests. 4) Roche estimated $600 million in annual synergies from the merger in June 2008.