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AHA 2006 and ESC 2008
• HTN
• CAD
• Valvular Heart Disease
• Congenital Heard Disease
• Inflammation
DCM/Congestive Cardiomiopathy
-Global hypokinesia
-Systolic failure
-Spherical shape cavity/dilation
-Normal/increase in total cardiac mass
-5-8/100k
-Viruses and gene mutations
HCM/Asymmetric HCM
-Beta myosin heavy chain and Binding Protein C
-Hyperkinetic
-Diastolic/Systolic dysfunction
-50% F (AD)/S
-100% Genetic
-Young athletes (sudden death)12-16mm
RCM
-Infiltration ( abnormal protein, sarcoidosis granuloma,
hemochromatosis)
-Failure to relaxation (Diastole dysfunction)
-NonHypertrophic/Dilated
-Endomyocardial fibrosis (Eo; Apical and subvalvular)
Arrhythmogenic right ventricular CM
• RV free Wallfibrous/fatty tussue w/ scattered residual myocardial
cells.
• Regional akinesis
• Desmosomal genes (40-60%)
Unclassified cardiomyopathies
• Left Ventricular noncompaction
- Cavity and Deep intratrabecular recesses
- HF, TE, Arrhythmias
• Stress-induced cardiomyopathy (takotsubo)
-transient systolic dysfunction of apical or mid segments of LV by stress

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Cardiomiopathy

  • 1. AHA 2006 and ESC 2008 • HTN • CAD • Valvular Heart Disease • Congenital Heard Disease • Inflammation
  • 2. DCM/Congestive Cardiomiopathy -Global hypokinesia -Systolic failure -Spherical shape cavity/dilation -Normal/increase in total cardiac mass -5-8/100k -Viruses and gene mutations
  • 3. HCM/Asymmetric HCM -Beta myosin heavy chain and Binding Protein C -Hyperkinetic -Diastolic/Systolic dysfunction -50% F (AD)/S -100% Genetic -Young athletes (sudden death)12-16mm
  • 4. RCM -Infiltration ( abnormal protein, sarcoidosis granuloma, hemochromatosis) -Failure to relaxation (Diastole dysfunction) -NonHypertrophic/Dilated -Endomyocardial fibrosis (Eo; Apical and subvalvular)
  • 5. Arrhythmogenic right ventricular CM • RV free Wallfibrous/fatty tussue w/ scattered residual myocardial cells. • Regional akinesis • Desmosomal genes (40-60%)
  • 6. Unclassified cardiomyopathies • Left Ventricular noncompaction - Cavity and Deep intratrabecular recesses - HF, TE, Arrhythmias • Stress-induced cardiomyopathy (takotsubo) -transient systolic dysfunction of apical or mid segments of LV by stress

Editor's Notes

  1. 50% familiar and 50% sporadic
  2. Ischemic has only segmental hypkinesia. Hypertrophy is equally distributed in all the muscle