This presentation discusses what makes Boston's startup scene special, including its intellectual capital from top universities like MIT and Harvard, its venture capital funding, and successful companies. It highlights Boston's leadership in key industries like life sciences and its high concentration of technology jobs. The presentation promotes Boston's resources and ecosystem for startups.

1. CONFIDENTIAL PRESENTATION | PAGE 1
What Makes Boston’s Start-Up
Scene Special?
Jeff Bussgang
General Partner, Flybridge Capital Partners
Senior Lecturer, Harvard Business School
Fall 2015

2. CONFIDENTIAL PRESENTATION | PAGE 2
 Intellectual Capital – academia, innovation,
diverse industries and ideas
 Advisors, Angels, Accelerators- seed $
 Venture Capital – scale $, mentorship
 Successful Companies – to partner, poach
and/or sell to
Ingredients for a Vibrant Start-Up Ecosystem

3. CONFIDENTIAL PRESENTATION | PAGE 3
Historical Leadership

4. CONFIDENTIAL PRESENTATION | PAGE 4
MIT – Factory of Innovation

5. CONFIDENTIAL PRESENTATION | PAGE 5
Harvard Is No Slouch

6. CONFIDENTIAL PRESENTATION | PAGE 6
Other Colleges and Universities

7. CONFIDENTIAL PRESENTATION | PAGE 7
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
1.8
MA VA WA CA MD TX NC NY
Location Quotient (LQ)
Mass Tech Sector - Most Concentrated in US
Source: MassTLC State of Technology Report – 2015
LQ is a way of defining how concentrated an industry cluster is compared to the national average

8. CONFIDENTIAL PRESENTATION | PAGE 8
Innovation Economy Is Densely Concentrated
Population: 640k Boston, 4.5m Greater Boston Area
40% of workforce in an innovation economy sector

9. CONFIDENTIAL PRESENTATION | PAGE 9
Geographic Clusters Benefits of High Concentration
495 Corridor
128 Corridor
Cambridge/Boston

10. CONFIDENTIAL PRESENTATION | PAGE 10
“Highest Density Cluster of Innovation on the Planet”
Kendall Square

11. CONFIDENTIAL PRESENTATION | PAGE 11
Boston’s Innovation District

12. CONFIDENTIAL PRESENTATION | PAGE 12
Next Up: Harvard - Allston

13. CONFIDENTIAL PRESENTATION | PAGE 13
Venture Capital: Regional Comparison
California:
$85B
New York:
$20B
Massachusetts:
$20B
VC Capital Under Management - 2014
Source: NVCA 2015 Yearbook
80% of total VC $ in these 3 regions

14. CONFIDENTIAL PRESENTATION | PAGE 14
Venture Capital Per Capita
California:
$3.7k/person
New York:
$1.0k/person
Massachusetts:
$4.3k/person
VC Capital Under Management Per Capita - 2014
Source: NVCA 2015 Yearbook, US Census, CA is counted as four MSAs (LA, SF, San Jose, San Diego)

15. CONFIDENTIAL PRESENTATION | PAGE 15
Proximity to NYC: A Huge Plus

16. CONFIDENTIAL PRESENTATION | PAGE 16
Leading Clusters: Life Sciences Leadership

17. CONFIDENTIAL PRESENTATION | PAGE 17
Leading Clusters: Boston’s Energy Sector

18. CONFIDENTIAL PRESENTATION | PAGE 18
MicroClusters Matter:
For Example, Mobile
• Over 100 VC-backed mobile start-ups
• Seven >$100M exits:
• Crashlytics (Twitter)
• Enpocket (Nokia)
• Jumptap (Millenial Media)
• M-Qube (Verisign)
• Quattro (Apple)
• Third Screen (AOL)
• Where (PayPal)

19. CONFIDENTIAL PRESENTATION | PAGE 19
Other MicroClusters
Cloud Computing
Cybersecurity
Health IT
Marketing
Tech
Education

20. CONFIDENTIAL PRESENTATION | PAGE 20
Strong Community of Women Tech Leaders
#2 “Top Cities for Female Entrepreneurs” - Forbes
Cynthia Brezeal
Jibo
Wendy Cebula
EdX
Abbie Celniker
Eleven Bio
Michelle Dipp
Ovascience
Gail Goodman
Constant Contact
Helen Greiner
CyPhy/iRobot
Bettina Hein
Pixability
Sheila Marcelo
Care.com

21. CONFIDENTIAL PRESENTATION | PAGE 21
Market caps as of 9/8/2015
$47B
$38B
$17B
$13B
$10B
$5B
$5B







$71B
$49B
$31B
$11B
$10B
$8B
$5B






Tech Life Sciences
Boston-Based Platform Companies
Market Capitalization >$5B

22. CONFIDENTIAL PRESENTATION | PAGE 22
Expansion of Major Tech Companies

23. CONFIDENTIAL PRESENTATION | PAGE 23
Start-up Resources

24. CONFIDENTIAL PRESENTATION | PAGE 24
HubWeek Example: October 3-10
• Register: http://ow.ly/RSnmh
Michael Sandel’s MasterClass at Fenway
http://www.harvard.edu/hubweek

25. CONFIDENTIAL PRESENTATION | PAGE 25
Harvard Start-up Resources
1. Ajay Agarwal – Bain Capital
2. Julia Austin – Austinfish
3. Steve Bonner – Cancer Treatment
4. David Chang – Paypal
5. Sam Clemens – InsightSquared
6. Chuck Davis – TCV
7. David Frankel – Founder Collective
8. Janet Kraus – Peach/Circles
9. Sharon Peyer – Hitbliss
10. Jules Pieri – The Grommet
11. Ruben Pinchanski – Digitas
12. Katie Rae – Techstars Boston
13. Duke Rohlen - Spirox
14. Rudina Seseri – Fairhaven Capital
15. Martin Sinozich – Venn Capital
16. Jim Sharpe – HBS/Extrusion Tech
17. Michael Skok – Assemble
18. Jim Southern – Pacific Lake
19. Russ Wilcox – E Ink/Transatomic
NYC STARTUP TREK
Campus ResourcesHBS EIRs – 2015-16

26. CONFIDENTIAL PRESENTATION | PAGE 26
Investors and Entrepreneurs to Follow
Investors Blog URL Twitter
Rob Go / Next View robgo.org @robgo
Chip Hazard / Flybridge hazard.typepad.com @chazard
Bijan Sabet / Spark bijansabet.com @bijan
David Skok / Matrix forentrepreneurs.com @bostonvc
Michael Skok / Assemble mjskok.com @mjskok
Entrepreneurs Blog URL Twitter
David Cancel/Drifft davidcancel.com @dcancel
David Chang/ex-PayPal @changds
Wayne Chang/Twitter waynechang.com @wayne
Diane Hessan/StartUp Inst @DianeHessan
Sean Lindsay/Tapjoy @rseanlindsay
Jules Pieri/DailyGrommet jules.thegrommit.com @julespieri
Dharmesh Shah/Hubspot onstartups.com @dharmesh
Mike Troiano/Actifio medium.com/@miketrap @miketrap

27. CONFIDENTIAL PRESENTATION | PAGE 27
Conclusion: Top Ranked Innovation City
It’s All Here Waiting For You