Bones 011910
•Download as PPT, PDF•
3 likes•820 views
The document summarizes research on the mechanical and physical properties of demineralized and deproteinated bones. It discusses how bones have a hierarchical structure composed of mineral (hydroxyapatite) and protein (collagen) components. Experiments were conducted to compress intact, demineralized, and deproteinated bovine femur and elk antler samples to analyze how removing minerals or proteins affects their mechanical properties. Results showed demineralized bone behaved like a composite material while intact bone's strength relies on its mineral characteristics.
Report
Share
Report
Share
![Introduction ,[object Object],[object Object],[object Object],[object Object]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
Recommended
20. STR OF BONE - LAMBERT
This document provides an overview of the structure of bone. It begins by classifying bones based on their location in the body, shape, size, texture, matrix arrangement, maturity, and developmental origin. It then discusses the composition, anatomy, microscopic structure, histogenesis, dynamics, functions, calcium and phosphate metabolism, mineralization, blood supply, and development of facial bones in detail across multiple sections. The document is a comprehensive review of the structure and properties of bone intended to educate readers on this important tissue.
alveolar bone
The document summarizes the mechanism of alveolar bone destruction in periodontitis. It discusses the structure of alveolar bone and the process of bone remodeling which is regulated by factors that control bone resorption and formation. Key cytokines like IL-1, IL-6, TNF-α play a role in bone resorption by stimulating osteoclastogenesis directly or indirectly via prostaglandins. The balance between these resorptive and formative factors is important in maintaining bone homeostasis, and an imbalance leads to periodontal bone loss.
Metabolic bone diseases, pathology dept
This document discusses metabolic bone diseases. It begins by describing the basic structure and function of bone, including its cellular components like osteoblasts and osteoclasts. It then discusses the constituents of bone matrix, including collagen, proteoglycans, and minerals. Bone development and homeostasis are explained, involving processes like remodeling. Specific metabolic bone diseases are then outlined in more detail, including osteogenesis imperfecta (brittle bone disease), osteomalacia/rickets due to abnormal mineralization, and hypophosphatasia due to a genetic disturbance in alkaline phosphatase synthesis. Throughout, the document provides microscopic and radiographic characteristics of these conditions.
TheSkeletalSystem
The skeletal system is made up of bones, cartilage, ligaments, and connective tissues. It has five main functions: providing support and structure to the body, protecting organs, storing minerals, allowing movement through levers, and consisting of two tissue types - cartilage and bone. Vitamin D deficiency can result from lack of sunlight exposure and negatively impact the skeletal system by inhibiting calcium absorption, leading to conditions like rickets, osteomalacia, and osteoporosis over time. Osteoporosis causes bones to become thin and brittle, increasing fracture risk, and can be diagnosed through bone density tests and treated through medications that regulate bone remodeling. Maintaining a healthy skeletal system is important for human functionality.
Disorders Of The Bone By Yapa Wijeratne
Presentation on disorders of the bone which explains the biochemical & physiological aspects with illustrations.
Introduction to Common Bone Disorders
This document provides an introduction to common bone disorders. It begins by defining bone and its importance in providing structure, protection, and a site for blood cell production. Bone disorders are divided into congenital and acquired categories. Congenital disorders include Osteogenesis Imperfecta, Achondroplasia, and Osteopetrosis. Acquired or metabolic bone diseases are caused by abnormalities in minerals, vitamins, bone mass or structure and include Osteoporosis, Paget's Disease, Rickets/Osteomalacia, and Hyperparathyroidism. Each condition is briefly characterized in terms of symptoms and causes of abnormal bone structure or composition.
anatomy 2 paper
The skeletal system provides many essential functions to the human body, including structure, protection, movement, and blood cell production. It is composed of 206 bones divided into the axial and appendicular skeleton. Certain diseases and toxins can negatively impact bone health. Osteoporosis is caused by vitamin D deficiency from lack of sunlight and is characterized by brittle bones that break easily. Exposure to toxins like lead and behaviors like smoking can also increase osteoporosis risk by disrupting bone cells. Maintaining a healthy lifestyle through nutrition, exercise, and avoiding toxins can help prevent osteoporosis and keep the skeletal system functioning properly.
Bio powerpoint
The skeletal system provides structure, protection, movement, and blood cell production for the body. It is made up of bones, cartilage, tendons, and ligaments. Bones are living tissues composed of calcium, phosphorus, and other minerals. They are constantly being remodeled by osteoblasts, osteoclasts, and osteocytes in response to stresses. The skeletal system works with other body systems like the muscular and circulatory systems to enable movement and transport nutrients. Diseases like osteosarcoma can affect the bones.
Recommended
20. STR OF BONE - LAMBERT
This document provides an overview of the structure of bone. It begins by classifying bones based on their location in the body, shape, size, texture, matrix arrangement, maturity, and developmental origin. It then discusses the composition, anatomy, microscopic structure, histogenesis, dynamics, functions, calcium and phosphate metabolism, mineralization, blood supply, and development of facial bones in detail across multiple sections. The document is a comprehensive review of the structure and properties of bone intended to educate readers on this important tissue.
alveolar bone
The document summarizes the mechanism of alveolar bone destruction in periodontitis. It discusses the structure of alveolar bone and the process of bone remodeling which is regulated by factors that control bone resorption and formation. Key cytokines like IL-1, IL-6, TNF-α play a role in bone resorption by stimulating osteoclastogenesis directly or indirectly via prostaglandins. The balance between these resorptive and formative factors is important in maintaining bone homeostasis, and an imbalance leads to periodontal bone loss.
Metabolic bone diseases, pathology dept
This document discusses metabolic bone diseases. It begins by describing the basic structure and function of bone, including its cellular components like osteoblasts and osteoclasts. It then discusses the constituents of bone matrix, including collagen, proteoglycans, and minerals. Bone development and homeostasis are explained, involving processes like remodeling. Specific metabolic bone diseases are then outlined in more detail, including osteogenesis imperfecta (brittle bone disease), osteomalacia/rickets due to abnormal mineralization, and hypophosphatasia due to a genetic disturbance in alkaline phosphatase synthesis. Throughout, the document provides microscopic and radiographic characteristics of these conditions.
TheSkeletalSystem
The skeletal system is made up of bones, cartilage, ligaments, and connective tissues. It has five main functions: providing support and structure to the body, protecting organs, storing minerals, allowing movement through levers, and consisting of two tissue types - cartilage and bone. Vitamin D deficiency can result from lack of sunlight exposure and negatively impact the skeletal system by inhibiting calcium absorption, leading to conditions like rickets, osteomalacia, and osteoporosis over time. Osteoporosis causes bones to become thin and brittle, increasing fracture risk, and can be diagnosed through bone density tests and treated through medications that regulate bone remodeling. Maintaining a healthy skeletal system is important for human functionality.
Disorders Of The Bone By Yapa Wijeratne
Presentation on disorders of the bone which explains the biochemical & physiological aspects with illustrations.
Introduction to Common Bone Disorders
This document provides an introduction to common bone disorders. It begins by defining bone and its importance in providing structure, protection, and a site for blood cell production. Bone disorders are divided into congenital and acquired categories. Congenital disorders include Osteogenesis Imperfecta, Achondroplasia, and Osteopetrosis. Acquired or metabolic bone diseases are caused by abnormalities in minerals, vitamins, bone mass or structure and include Osteoporosis, Paget's Disease, Rickets/Osteomalacia, and Hyperparathyroidism. Each condition is briefly characterized in terms of symptoms and causes of abnormal bone structure or composition.
anatomy 2 paper
The skeletal system provides many essential functions to the human body, including structure, protection, movement, and blood cell production. It is composed of 206 bones divided into the axial and appendicular skeleton. Certain diseases and toxins can negatively impact bone health. Osteoporosis is caused by vitamin D deficiency from lack of sunlight and is characterized by brittle bones that break easily. Exposure to toxins like lead and behaviors like smoking can also increase osteoporosis risk by disrupting bone cells. Maintaining a healthy lifestyle through nutrition, exercise, and avoiding toxins can help prevent osteoporosis and keep the skeletal system functioning properly.
Bio powerpoint
The skeletal system provides structure, protection, movement, and blood cell production for the body. It is made up of bones, cartilage, tendons, and ligaments. Bones are living tissues composed of calcium, phosphorus, and other minerals. They are constantly being remodeled by osteoblasts, osteoclasts, and osteocytes in response to stresses. The skeletal system works with other body systems like the muscular and circulatory systems to enable movement and transport nutrients. Diseases like osteosarcoma can affect the bones.
Bio powerpoint
The skeletal system provides structure, protection, movement, and blood cell production for the body. It is made up of bones, cartilage, tendons, and ligaments. Bones are living tissues composed of calcium, phosphorus, and other minerals. They are constantly being remodeled by osteoblasts, osteoclasts, and osteocytes. The skeletal system works with other systems like the muscular and circulatory systems to allow movement and transport nutrients. Diseases like osteosarcoma can affect the bones.
Spinal Fusion: For Athlete’s Better Spine Health
Although they are in better physical health than most people, athletes are prone to all kinds of health conditions, including degenerative disc disease (DDD), the breakdown of intervertebral discs. The most popular treatment for DDD is spinal fusion. The surgery corrects problems with two or more bones of the spine, fusing with the vertebrae to form a single bone.
Alveolar bone perio.
This document provides information on alveolar bone structure and composition. It discusses the different types of bone cells that make up alveolar bone, including osteoprogenitor cells, osteoblasts, osteocytes, and osteoclasts. It also describes the composition and structural elements of alveolar bone, such as Sharpey's fibers, vascular supply, gross morphology, and the periosteum and endosteum layers.
Bone grafts 2006
The document discusses bone grafts, which are used to aid in healing and strengthening bones. There are several types of bone grafts, including autografts which use bone from the patient's own body, and allografts which use donated bone. Alternatives to bone grafts have also been developed, including substitutes made from ceramics, coral, or synthetic materials. The best type of bone graft depends on each patient's individual surgical situation and needs.
Skeletal System Slides
The skeletal system document summarizes key aspects of bone structure and function. It describes how bone is composed of mineral and organic components including collagen fibers. It discusses how aging affects bone remodeling and loss of bone density. It also outlines interventions that can help slow bone loss such as hormone therapy, medications, diet and exercise. Diagrams illustrate bone density changes with aging and risks of fracture.
CVA A&P - Chapter 5a: Honors Bone Tissue
The document summarizes key aspects of the skeletal system, including that it has 206 bones divided into the axial and appendicular skeleton, bones have various shapes and serve functions like protection and movement, and long bones have specific internal structures. It also outlines bone cell types, growth and remodeling, common fractures, and the fracture healing process.
23. BONE PATHOLOGIES - LAMBERT
This document provides an overview of bone pathologies and classifications of bone diseases. It begins with an introduction to bone diseases and classifications including by tissue affected, metabolic basis, and decreased/increased bone mass. It then covers specific conditions like skeletal dysplasias, metabolic bone diseases, infections, tumors, fractures and cysts. The document also provides the WHO classification of bone tumors and classifications of fibro-osseous lesions. In summary, the document classifies and describes a wide range of bone diseases, conditions, and lesions.
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان Prof Freih Abu Hassan البروفيسور فريح ابوحسان
جراحة العظام / علاج العظام في الاردن / افضل دكتور عظام في الاردن / افضل اخصائي عظام في الاردن / استشاري عظام/افضل استشاري عظام في الاردن /جراحة عظام / /عمليات تطويل العظام في الاردن / اطباء العظام في الاردن / دكتور طب عظام في الاردن / الاطباء في الاردن / خلع ورك / عمليات اليزاروف في الاردن /علاج الكسور /خلع الولادة / تركيب المفصل / اوجاع العظام /افضل طبيب عظام اطفال في الاردن / استشاري اطفال عظام في الاردن / /علاج خلع الكتف / علاج التواء الكاحل / التواء الكاحل / علاج الام العظام / علاج هشاشة العظام / ارقام اطباء عظام في الاردن / مشاكل العظام والمفاصل /مستشار جراحة العظام والمفاصل والكسور/ مستشار جراحة عظام الأطفال.
هشاشة العظام ، امراض العظام ، امراض العظام الناتجة عن اضطراب الايضPreventing Osteoporosis
The document discusses preventing osteoporosis and the role of genetics in bone health. It notes that moderate and vigorous physical activity can increase bone density, especially in older women, but genetics still explain 40-75% of the variation in bone mineral content, density, and size between individuals. Many factors related to bone health like parathyroid hormone levels, vitamin D metabolism, bone formation markers, and calcium excretion are highly influenced by genetics as well.
Osteopetrosis
This document discusses osteopetrosis, also known as marble bone disease, which is a rare hereditary disorder characterized by defective osteoclast function that results in abnormally dense and brittle bones. There are two subtypes: infantile autosomal recessive osteopetrosis, which is more severe and often fatal in childhood, and autosomal dominant osteopetrosis, which is less severe and allows survival into adulthood. The document describes the clinical features, radiographic findings, differential diagnoses, and key features that distinguish osteopetrosis from similar conditions like pyknodysostosis and melorheostosis.
Skeletal system
This document discusses osteoporosis and bone fractures. It defines osteoporosis as a bone disease where the body fails to form enough new bone or absorbs too much old bone. It affects more women after menopause and men after age 70. Bone fractures are breaks in the bone that can result from injury or diseases like osteoporosis. Symptoms include bone pain, loss of height, and fractures from minor impacts. Treatment involves lifestyle changes, medications, and exercise to reduce fracture risk and build strong bones.
Osteomalacia new org
This presentation summarizes osteomalacia, a metabolic bone disease characterized by inadequate bone mineralization. It discusses the pathophysiology involving insufficient hydroxyapatite deposition in bone matrix due to vitamin D deficiency or malabsorption. Common causes include lack of sun exposure, low dietary calcium, gastrointestinal/renal disorders, and certain drugs. Clinical features are nonspecific bone pain and tenderness but can include skeletal deformities. Diagnosis involves low serum calcium, vitamin D, and elevated alkaline phosphatase. Treatment focuses on vitamin D supplementation, calcium, and treating underlying causes. The presentation provides examples of radiological findings and concludes with a question and answer segment to reinforce key points.
Common Diseases/ Disorders of the Bones
Rickets is a bone deformity caused by low levels of calcium and phosphorus in the blood due to poor nutrition or lack of vitamin D. Arthritis is a disease of the joints that causes pain, stiffness, and swelling, and can cripple its victims. Osteoporosis is a disease where bone tissue is lost, bones become thinner and can disappear, resulting in extremely weak and fragile bones throughout the skeleton that can fracture from minor injuries.
Osteoblast-Osteoclast Interactions
This document summarizes research on communication between osteoblasts and osteoclasts, the two main cells involved in bone remodeling. It discusses how osteoblasts can affect osteoclast formation and differentiation through several pathways, such as OPG/RANKL/RANK, ephrin2/ephB4, and M-CSF. It also reviews how osteoclasts can influence osteoblast activity through factors like Atp6v0d2. Direct cell-cell contact and cytokines released from resorbed bone matrix also facilitate communication between osteoblasts and osteoclasts. Imbalances in this communication can lead to bone diseases like osteoporosis.
bioabsorbable interference screw
The document discusses properties required for interference screws used in ACL reconstruction. It examines the use of poly(lactic acid) (PLA) screws, noting their biocompatibility and biodegradability are advantages over traditional titanium. However, PLA has limitations like a slow degradation rate. Recent research explores modifying PLA and using other materials like magnesium alloys to improve bone regeneration and allow for controlled degradation while maintaining sufficient strength.
Elastic discontinuities and stress concentrations
Load-mediated adaptive process necessary to accommodate functional and/or therapeutic forces (including orthopedic fixation devices and orthodontic braces). This is because forces generate strain
fields in tissue matrices and at the soft-hard and hard-hard biological tissue interfaces of an organ; cell-cell and cell-matrix interactions, through integrin-based coupling, sense these tension- and compression- based strain fields. Function-based mechanical energy is then
transduced to chemical energy through cells' biochemical expression. The type and concentration of biochemicals can cause mineral formation or resorption, which, within an
organ's tension-compression based matrices, alters the overall morphology and function of a load bearing joint.
Finite Element Analysis of Human RIB Cage
This paper of finite element analysis of the rib cage model is applied to recognize stress distributions and to determine the rate of bone fractures(especially for pathologically changed bones). Also to determine the load and stress to occurs on the human rib cage at any accident. Also find the maximum load sustain capacity of human rib cage and according to the load sustain capacity of the human rib cage by finite element analysis and search a material as like a bone cement and it take on a rib fracture and see the result . This paper is only of to nullify the rib fracture as present medical treatment give the elastic belt but due to respiration, the human ribs are contract and relax that’s the rib fracture are only minimize not a nullify. The human models are considered in between age 15 to 40 year. The Simulation result shows a good agreement with the cadaver test data.
Can anterior cruciate ligament injuries be mitigated?
Overall, despite much scientific research, the incidence and prevalence of ACL injuries still remains high. I do not believe ACL injuries can be completely mitigated as they are so multi-factorial and involve both contact and non-contact situations. And although preventative programs have been found to reduce the incidence of ACL injuries by up to 90% in some cases, I still believe a lot more research needs to be conducted in regards to how much training stimulus is required to produce a protective effect. I understand that many coaches may be sceptical in regards to employing a preventative program, but the research indicates even something as simple as plyometric training can help train neuromuscular control and improve lower leg strength. Overall, I believe something is better than nothing, and if more often than not intervention programs are producing positive outcomes, the coaches really have nothing to lose.
The key is to achieve widespread awareness and widespread use; so spread this presentation and message so we can achieve this and help reduce the debilitating consequences this injury has on so many young athletes.
Osteoporosis
Osteoporosis is a bone disease where parts of the bone become weak and prone to fracture. This condition is more common in seniors, but can affect men and women of all ages. Because women have 30% less bone mass than men, women are particularly prone to osteoporosis as they age.
Basic bone biology
This document provides an overview of bone biology and its relevance to orthodontics. It discusses the gross anatomy and types of bone, including cortical and trabecular bone. It describes the cells involved - osteoblasts which build bone, and osteoclasts which resorb it. The periodic dental ligament is described as the soft tissue between cementum and alveolar bone. Bone composition, structure, modeling and remodeling processes are summarized. The roles of calcium, phosphorus, collagen and other components are outlined.
Biomechanics of Bones
This document provides an overview of bone biomechanics. It discusses the composition and types of bones, as well as their main functions of protecting organs and supporting the body. Bones are made up of collagen fibers and bone cells. There are two types of bone tissue: cortical bone and cancellous bone. Bones can be categorized into four basic shapes: long bones, short bones, flat bones, and irregular bones. The document then covers the mechanical properties of bone, explaining that bone has high compressive but low tensile strength. It analyzes the biomechanics of bone in terms of stress, strain, elasticity, plasticity, and failure points. In summary, the document provides a comprehensive review of bone composition, structure,
Structural behavior of bones in human body
This presentation discusses the structural behavior of bones in the human body and their similarities to reinforced concrete structures. It covers the composition, structure, mechanical properties and loading of bones. Bones provide mechanical support, facilitate movement, and act as reservoirs for minerals. Their organic and inorganic components give them flexibility and rigidity. Bones experience various loads like tension, compression, bending and torsion from forces like gravity, muscles and impacts. Their mechanical behavior and properties change with age in a similar manner to concrete. Failure mechanisms in bones like repetitive stress and fractures are also reviewed alongside repair techniques that parallel those used for reinforced concrete.
More Related Content
What's hot
Bio powerpoint
The skeletal system provides structure, protection, movement, and blood cell production for the body. It is made up of bones, cartilage, tendons, and ligaments. Bones are living tissues composed of calcium, phosphorus, and other minerals. They are constantly being remodeled by osteoblasts, osteoclasts, and osteocytes. The skeletal system works with other systems like the muscular and circulatory systems to allow movement and transport nutrients. Diseases like osteosarcoma can affect the bones.
Spinal Fusion: For Athlete’s Better Spine Health
Although they are in better physical health than most people, athletes are prone to all kinds of health conditions, including degenerative disc disease (DDD), the breakdown of intervertebral discs. The most popular treatment for DDD is spinal fusion. The surgery corrects problems with two or more bones of the spine, fusing with the vertebrae to form a single bone.
Alveolar bone perio.
This document provides information on alveolar bone structure and composition. It discusses the different types of bone cells that make up alveolar bone, including osteoprogenitor cells, osteoblasts, osteocytes, and osteoclasts. It also describes the composition and structural elements of alveolar bone, such as Sharpey's fibers, vascular supply, gross morphology, and the periosteum and endosteum layers.
Bone grafts 2006
The document discusses bone grafts, which are used to aid in healing and strengthening bones. There are several types of bone grafts, including autografts which use bone from the patient's own body, and allografts which use donated bone. Alternatives to bone grafts have also been developed, including substitutes made from ceramics, coral, or synthetic materials. The best type of bone graft depends on each patient's individual surgical situation and needs.
Skeletal System Slides
The skeletal system document summarizes key aspects of bone structure and function. It describes how bone is composed of mineral and organic components including collagen fibers. It discusses how aging affects bone remodeling and loss of bone density. It also outlines interventions that can help slow bone loss such as hormone therapy, medications, diet and exercise. Diagrams illustrate bone density changes with aging and risks of fracture.
CVA A&P - Chapter 5a: Honors Bone Tissue
The document summarizes key aspects of the skeletal system, including that it has 206 bones divided into the axial and appendicular skeleton, bones have various shapes and serve functions like protection and movement, and long bones have specific internal structures. It also outlines bone cell types, growth and remodeling, common fractures, and the fracture healing process.
23. BONE PATHOLOGIES - LAMBERT
This document provides an overview of bone pathologies and classifications of bone diseases. It begins with an introduction to bone diseases and classifications including by tissue affected, metabolic basis, and decreased/increased bone mass. It then covers specific conditions like skeletal dysplasias, metabolic bone diseases, infections, tumors, fractures and cysts. The document also provides the WHO classification of bone tumors and classifications of fibro-osseous lesions. In summary, the document classifies and describes a wide range of bone diseases, conditions, and lesions.
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان Prof Freih Abu Hassan البروفيسور فريح ابوحسان
جراحة العظام / علاج العظام في الاردن / افضل دكتور عظام في الاردن / افضل اخصائي عظام في الاردن / استشاري عظام/افضل استشاري عظام في الاردن /جراحة عظام / /عمليات تطويل العظام في الاردن / اطباء العظام في الاردن / دكتور طب عظام في الاردن / الاطباء في الاردن / خلع ورك / عمليات اليزاروف في الاردن /علاج الكسور /خلع الولادة / تركيب المفصل / اوجاع العظام /افضل طبيب عظام اطفال في الاردن / استشاري اطفال عظام في الاردن / /علاج خلع الكتف / علاج التواء الكاحل / التواء الكاحل / علاج الام العظام / علاج هشاشة العظام / ارقام اطباء عظام في الاردن / مشاكل العظام والمفاصل /مستشار جراحة العظام والمفاصل والكسور/ مستشار جراحة عظام الأطفال.
هشاشة العظام ، امراض العظام ، امراض العظام الناتجة عن اضطراب الايضPreventing Osteoporosis
The document discusses preventing osteoporosis and the role of genetics in bone health. It notes that moderate and vigorous physical activity can increase bone density, especially in older women, but genetics still explain 40-75% of the variation in bone mineral content, density, and size between individuals. Many factors related to bone health like parathyroid hormone levels, vitamin D metabolism, bone formation markers, and calcium excretion are highly influenced by genetics as well.
Osteopetrosis
This document discusses osteopetrosis, also known as marble bone disease, which is a rare hereditary disorder characterized by defective osteoclast function that results in abnormally dense and brittle bones. There are two subtypes: infantile autosomal recessive osteopetrosis, which is more severe and often fatal in childhood, and autosomal dominant osteopetrosis, which is less severe and allows survival into adulthood. The document describes the clinical features, radiographic findings, differential diagnoses, and key features that distinguish osteopetrosis from similar conditions like pyknodysostosis and melorheostosis.
Skeletal system
This document discusses osteoporosis and bone fractures. It defines osteoporosis as a bone disease where the body fails to form enough new bone or absorbs too much old bone. It affects more women after menopause and men after age 70. Bone fractures are breaks in the bone that can result from injury or diseases like osteoporosis. Symptoms include bone pain, loss of height, and fractures from minor impacts. Treatment involves lifestyle changes, medications, and exercise to reduce fracture risk and build strong bones.
Osteomalacia new org
This presentation summarizes osteomalacia, a metabolic bone disease characterized by inadequate bone mineralization. It discusses the pathophysiology involving insufficient hydroxyapatite deposition in bone matrix due to vitamin D deficiency or malabsorption. Common causes include lack of sun exposure, low dietary calcium, gastrointestinal/renal disorders, and certain drugs. Clinical features are nonspecific bone pain and tenderness but can include skeletal deformities. Diagnosis involves low serum calcium, vitamin D, and elevated alkaline phosphatase. Treatment focuses on vitamin D supplementation, calcium, and treating underlying causes. The presentation provides examples of radiological findings and concludes with a question and answer segment to reinforce key points.
Common Diseases/ Disorders of the Bones
Rickets is a bone deformity caused by low levels of calcium and phosphorus in the blood due to poor nutrition or lack of vitamin D. Arthritis is a disease of the joints that causes pain, stiffness, and swelling, and can cripple its victims. Osteoporosis is a disease where bone tissue is lost, bones become thinner and can disappear, resulting in extremely weak and fragile bones throughout the skeleton that can fracture from minor injuries.
Osteoblast-Osteoclast Interactions
This document summarizes research on communication between osteoblasts and osteoclasts, the two main cells involved in bone remodeling. It discusses how osteoblasts can affect osteoclast formation and differentiation through several pathways, such as OPG/RANKL/RANK, ephrin2/ephB4, and M-CSF. It also reviews how osteoclasts can influence osteoblast activity through factors like Atp6v0d2. Direct cell-cell contact and cytokines released from resorbed bone matrix also facilitate communication between osteoblasts and osteoclasts. Imbalances in this communication can lead to bone diseases like osteoporosis.
bioabsorbable interference screw
The document discusses properties required for interference screws used in ACL reconstruction. It examines the use of poly(lactic acid) (PLA) screws, noting their biocompatibility and biodegradability are advantages over traditional titanium. However, PLA has limitations like a slow degradation rate. Recent research explores modifying PLA and using other materials like magnesium alloys to improve bone regeneration and allow for controlled degradation while maintaining sufficient strength.
Elastic discontinuities and stress concentrations
Load-mediated adaptive process necessary to accommodate functional and/or therapeutic forces (including orthopedic fixation devices and orthodontic braces). This is because forces generate strain
fields in tissue matrices and at the soft-hard and hard-hard biological tissue interfaces of an organ; cell-cell and cell-matrix interactions, through integrin-based coupling, sense these tension- and compression- based strain fields. Function-based mechanical energy is then
transduced to chemical energy through cells' biochemical expression. The type and concentration of biochemicals can cause mineral formation or resorption, which, within an
organ's tension-compression based matrices, alters the overall morphology and function of a load bearing joint.
Finite Element Analysis of Human RIB Cage
This paper of finite element analysis of the rib cage model is applied to recognize stress distributions and to determine the rate of bone fractures(especially for pathologically changed bones). Also to determine the load and stress to occurs on the human rib cage at any accident. Also find the maximum load sustain capacity of human rib cage and according to the load sustain capacity of the human rib cage by finite element analysis and search a material as like a bone cement and it take on a rib fracture and see the result . This paper is only of to nullify the rib fracture as present medical treatment give the elastic belt but due to respiration, the human ribs are contract and relax that’s the rib fracture are only minimize not a nullify. The human models are considered in between age 15 to 40 year. The Simulation result shows a good agreement with the cadaver test data.
Can anterior cruciate ligament injuries be mitigated?
Overall, despite much scientific research, the incidence and prevalence of ACL injuries still remains high. I do not believe ACL injuries can be completely mitigated as they are so multi-factorial and involve both contact and non-contact situations. And although preventative programs have been found to reduce the incidence of ACL injuries by up to 90% in some cases, I still believe a lot more research needs to be conducted in regards to how much training stimulus is required to produce a protective effect. I understand that many coaches may be sceptical in regards to employing a preventative program, but the research indicates even something as simple as plyometric training can help train neuromuscular control and improve lower leg strength. Overall, I believe something is better than nothing, and if more often than not intervention programs are producing positive outcomes, the coaches really have nothing to lose.
The key is to achieve widespread awareness and widespread use; so spread this presentation and message so we can achieve this and help reduce the debilitating consequences this injury has on so many young athletes.
Osteoporosis
Osteoporosis is a bone disease where parts of the bone become weak and prone to fracture. This condition is more common in seniors, but can affect men and women of all ages. Because women have 30% less bone mass than men, women are particularly prone to osteoporosis as they age.
What's hot (19)
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان
Orthopedic disorders of metabolic bone disease - البروفيسور فريح عوده ابوحسان
Can anterior cruciate ligament injuries be mitigated?
Can anterior cruciate ligament injuries be mitigated?
Similar to Bones 011910
Basic bone biology
This document provides an overview of bone biology and its relevance to orthodontics. It discusses the gross anatomy and types of bone, including cortical and trabecular bone. It describes the cells involved - osteoblasts which build bone, and osteoclasts which resorb it. The periodic dental ligament is described as the soft tissue between cementum and alveolar bone. Bone composition, structure, modeling and remodeling processes are summarized. The roles of calcium, phosphorus, collagen and other components are outlined.
Biomechanics of Bones
This document provides an overview of bone biomechanics. It discusses the composition and types of bones, as well as their main functions of protecting organs and supporting the body. Bones are made up of collagen fibers and bone cells. There are two types of bone tissue: cortical bone and cancellous bone. Bones can be categorized into four basic shapes: long bones, short bones, flat bones, and irregular bones. The document then covers the mechanical properties of bone, explaining that bone has high compressive but low tensile strength. It analyzes the biomechanics of bone in terms of stress, strain, elasticity, plasticity, and failure points. In summary, the document provides a comprehensive review of bone composition, structure,
Structural behavior of bones in human body
This presentation discusses the structural behavior of bones in the human body and their similarities to reinforced concrete structures. It covers the composition, structure, mechanical properties and loading of bones. Bones provide mechanical support, facilitate movement, and act as reservoirs for minerals. Their organic and inorganic components give them flexibility and rigidity. Bones experience various loads like tension, compression, bending and torsion from forces like gravity, muscles and impacts. Their mechanical behavior and properties change with age in a similar manner to concrete. Failure mechanisms in bones like repetitive stress and fractures are also reviewed alongside repair techniques that parallel those used for reinforced concrete.
SIMONA CAVALU_Alternative approaches using animal model for implant biomaterials
This document summarizes an animal study testing new dental and orthopedic implant materials. It discusses the motivation for animal testing prior to human clinical trials. It describes the materials to be tested - dense alumina-zirconia composites. Small animal models (Wistar rats) and larger animal models (rabbits) are proposed. The surgical procedures, monitoring, and analysis methods are outlined, including radiography, histology, and SEM/EDX to examine the bone-implant interface. Preliminary conclusions suggest the materials show good biocompatibility in animals and that surface coatings could improve biological response. The study involves collaboration between universities in Romania and Turkey.
Bone density ppt
this gives a detailed description for the bone density consideration during implant placement.
The presentation is available upon request. Mail me at apurvathampi@gmail.com
ALVEOLAR BONE
Alveolar bone is a specialized, mineralized connective tissue that supports the roots of the teeth
Alveolar bone is the least stable of the periodontal tissues because the structure is in constant state of flux.
Alveolar bone
This document provides an overview of bone histology and development. It discusses that bone is a specialized mineralized connective tissue that can be divided into compact and cancellous bone microscopically. Bone develops through either endochondral or intramembranous ossification. The key cells involved are osteoblasts, which form new bone, and osteoclasts, which resorb bone. Bone is remodeled throughout life by the balanced actions of these cells.
Bone Biology
Bone is a highly vascular mineralized connective tissue, consisting of cells and an intercellular matrix in which the great majority of its cells are embedded. Details about Bone, Bone morphology, Bone Cells, Bone Functions.
Hierarchical Bone
The document discusses the hierarchical structure and mechanical properties of bone. At the macrostructural level, bone is divided into cortical and cancellous bone based on their density. Cortical bone forms the hard outer shell, while cancellous bone is found at the interior and has an irregular structure. Cancellous bone remodels more frequently than cortical bone. Mechanical properties vary between cortical and cancellous bone as well as between different bones and regions within the same bone.
Tissue engineering of bone
This document provides an overview of tissue engineering of bone. It discusses the objectives of understanding bone formation/repair and the components of bone tissue engineering. The key components are scaffolds, growth factors, and cells. Various materials are described for use as scaffolds, including metals, ceramics, and polymers. Growth factors can stimulate bone formation and fracture healing. In vitro models are used to test and screen growth factors and their effects on bone marrow stem cells and cell lines prior to in vivo studies. Bone's macroscopic structure and the processes of intramembranous and endochondral bone formation are also summarized.
Bone biology, healing and biomechanics
This document summarizes key topics in bone biology, healing, and biomechanics. It describes the histology and cells of bone, including woven bone in healing and lamellar bone in cortical and cancellous bone. It also outlines the basic biomechanics of bone, including its mechanical properties, stress-strain relationships, anisotropy, and Wolff's law stating bone will adapt to loads. Finally, it discusses forces on bone and the biomechanics of bone healing, noting the importance of low strain and dynamic loading for union.
Bone physiology
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Advancement in Scaffolds for Bone Tissue Engineering: A Review
In last decade, Tissue Engineering has moved a way ahead and has proposed solutions by replacing
the permanently or severely damaged tissues of our body. The field has expanded to tissue regeneration of
cartilage, bone, blood vessels, skin, etc. The domain of tissue engineering is very wide and is the combination of
bioengineering, biology & biochemistry. This review is focus on recent research advancement in bone tissue
engineering. Bone grafting techniques are used to replace the severely damaged due to any accident, trauma or
any disease. These are either allograft, autologous or synthetic bone properties similar to bone. Bone Tissue
Engineering is part of a synthetic technique and overcome the limitations faced in other two mentioned
techniques. Bone Tissue engineering is rapidly developing field and has become important due to its remarkable
therapeutic properties. Mesenchymal stem cells are used as starting cells in tissue regeneration. These cells get
differentiated into bone cells and start multiplying to form bone. One inevitable requirement of these growing
human cells is a strong support which helps in the proper growth. This support is known as scaffold, in tissue
engineering. For proper regeneration of cells scaffold materials plays vital importance in the field of bone tissue engineering. This review attempts is illustrate the biology of natural bone, various desirable properties of scaffold, biomaterials used for fabrication of scaffold and various fabrication techniques with examples of bone regenerate.
anatomy and histology of Bone-201221144633.pdf
This document discusses the anatomy, histology, and composition of bone. It describes the different forms of bone including long bones and flat bones, which are formed through different ossification processes. The microscopic structures of cortical and cancellous bone are also outlined. Cortical bone makes up the dense outer layer and is composed of concentric osteons. Cancellous or trabecular bone forms the inner layer and has a crossed lattice structure. Bone is made up of both inorganic and organic components. The inorganic portion is mostly hydroxyapatite crystals which provide compressive strength, while collagen gives tensile strength as the main organic component. Osteoblasts lay down new bone matrix, osteocytes are embedded in bone, and osteocl
anatomy and histology of Bone-201221144633.pdf
This document discusses the anatomy, histology, and composition of bone. It describes the different forms of bone including long bones and flat bones, which are formed through different ossification processes. The microscopic structures of cortical and cancellous bone are also outlined. Cortical bone makes up the dense outer layer and is composed of concentric osteons containing bone lamellae and central canals. Cancellous bone forms a crossed lattice within bones and has a high turnover rate. Bone is made up of both inorganic and organic components, with the inorganic phase providing compressive strength through calcium hydroxyapatite and the organic phase including collagen giving tensile strength. Osteoblasts produce new bone matrix, osteocytes maintain bone tissue, and
Anatomy and histology of bone
This document discusses the anatomy, histology, and composition of bone. It describes the different types of bones including long bones and flat bones, which are formed through different ossification processes. The microscopic and structural components of cortical and cancellous bone are examined, including osteons, lamellae, trabeculae, and bone cells. The inorganic and organic composition of bone is also summarized, with calcium hydroxyapatite providing compressive strength and collagen providing tensile strength. Key cell types involved in bone formation and resorption are osteoblasts, osteocytes, and osteoclasts.
Bone changes during ortho. tooth movement dr.anusha /certified fixed orthodon...
Bone changes during ortho. tooth movement dr.anusha /certified fixed orthodon...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078Tissue reaction to dentofacial orthopedic appliances /certified fixed orthodo...
Tissue reaction to dentofacial orthopedic appliances /certified fixed orthodo...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078Anatomy of bone..latest
This document discusses the anatomy of bone, including its structure, function, classification, development, and blood supply. It describes bone as a composite connective tissue made up of organic components like bone cells and collagen and inorganic components like calcium crystals. It classifies bone tissue into woven bone, lamellar bone, cortical bone, and cancellous bone. Bone development occurs through either intramembranous or endochondral ossification. Finally, it outlines the dynamic process of bone remodeling carried out by osteoblasts, osteoclasts, and the blood supply to bone.
Copy of biology1
This document discusses the biology of tooth movement and root resorption. It begins by describing the cells and tissues involved in the periodontium, including progenitor cells, synthetic cells (osteoblasts, fibroblasts, cementoblasts), and resorptive cells (osteoclasts, fibroblasts, cementoclasts). It then explains the pressure-tension theory of tooth movement, which involves mechanical forces causing the differentiation of osteoblasts and osteoclasts, and the release of chemical signals like prostaglandins and cytokines. The document outlines the stages of tooth movement, including initial degeneration and hyalinization of tissues under pressure, followed by elimination of destroyed tissue and establishment of new attachment. It notes the differential time
Similar to Bones 011910 (20)
SIMONA CAVALU_Alternative approaches using animal model for implant biomaterials
SIMONA CAVALU_Alternative approaches using animal model for implant biomaterials
Advancement in Scaffolds for Bone Tissue Engineering: A Review
Advancement in Scaffolds for Bone Tissue Engineering: A Review
Bone changes during ortho. tooth movement dr.anusha /certified fixed orthodon...
Bone changes during ortho. tooth movement dr.anusha /certified fixed orthodon...
Tissue reaction to dentofacial orthopedic appliances /certified fixed orthodo...
Tissue reaction to dentofacial orthopedic appliances /certified fixed orthodo...
Bones 011910
- 1. Mechanical and physical properties of demineralized and deproteinated bones Ekaterina Evdokimenko , Po-Yu Chen , Joshua Vasquez, Robert Urbaniak and Joanna McKittrick Mechanical and Aerospace Engineering Materials Science and Engineering Program UC San Diego Ana Castro-Cesena and Gustavo A. Hirata, Center for Nanoscience and Nanotechnology UNAM
- 4. Hierarchical Structure of Bone tropocollagen collagen fibrils osteon carbonated hydroxyapatite compact bone cancellous bone Elk ( Cervus canadensis )
- 5. Microstructure of bones and antlers Bovine femur 5% porosity Elk antler 9% porosity
- 7. Experimental Methods Long axis of antler/bone
- 8. Compact Bone Pictures Untreated bone Demineralized bone Deproteinated bone
- 9. Compression Behavior of Compact Bone Radial direction appears “the strongest” direction in a bone
- 10. Compression Behavior of Compact Bone A diagonal crack is the most common failure during the bone compression
- 11. Mechanical Properties of Compact Bone Partially demineralized bone behaves as a composite material
- 12. Mechanical Properties of Compact Bone
Editor's Notes
- Bone is a composite material, consisting of a biopolymer (collagen) and a mineral phase (carbonated hydroxiapatite).
- In our laboratory we investigate the properties of elk antlers (as young bones) and bovine femur (as mature bones).
- Through controlled, timed dep. and dem. studies we will determine how these processes affect the chemical composition and microstructure