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Introduction
Bleeding, or hemorrhage, is the name used to describe
blood loss. It can refer to blood loss inside the body,
called internal bleeding. Or it can refer to blood loss
outside of the body, called external bleeding.
Blood loss can occur in almost any area of the body.
Internal Bleeding: occurs when blood leaks out
through a damaged blood vessel or organ.
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Traumatic bleeding is caused by some type of injury,
There are types of wound which may cause traumatic
bleeding, These include:
Abrasion: also called a graze. This is caused by
transverse action of a foreign object against the skin.
And usually does not penetrate below the epidermis.
Traumatic Bleeding
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Medical Conditions
There are also some medical condition that can cause
bleeding due to a medical condition is less common
that traumatic bleeding.
Conditions that can cause bleeding include :
Hemophilia • Leukemia
Congenital heart failure • Endometriosis
Thrombocytopenia • Vitamin k deficiency
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Hemophilia
Hemophilia is an inherited bleeding disorder in which
a person lacks or has low levels of certain proteins
called [clotting factor] and the blood doesn’t clot
properly as a result ,there are 13 types of clotting
factors.
Types of hemophilia:
Hemophilia A
Hemophilia B
Hemophilia C
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Leukemia
Leukemia is a cancer of the blood cells. there are
several broad categories of blood cell including RBC,
WBC, and platelets .generally leukemia refers to
cancers of the WBC.
The types of leukemia :
AML [acute myelogenous leukemia]
ALL [acute lymphocytic leukemia]
CML [chronic myelogenous leukemia]
CLL [chronic lymphocytic leukemia]
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Congestive Heart Failure
Heart failure, sometimes known as congestive heart
failure, occurs when your heart muscle doesn't pump
blood as well as it should.
Certain conditions, such as narrowed arteries in your
heart (coronary artery disease) or high blood pressure,
heart failure can occur even with a normal ejection
fraction.
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Endometriosis
Endometriosis is an often painful disorder in which
tissue that normally lines the inside of your uterus (the
endometrium) grows outside your uterus. Endometriosis
most commonly involves your ovaries, fallopian tubes
and the tissue lining your pelvis
With endometriosis, displaced endometrial tissue breaks
down and bleeds with each menstrual cycle
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Thrombocytopenia
Low platelet count (Thrombocytopenia) the term refer
to a relative decrease of platelet in blood.
Signs & Symptoms:
Bleeding form your gums or nose
Blood in urine or stools
Easy or excessive bruising (purpura)
Fatigue and malaise
Treatment
Diagnose
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Vitamin K Deficiency
Vitamin k is a group of lipophilic hydrophobic vitamin, fat
soluble compound necessary for the synthesis of several
proteins required for blood clotting.
Function of vitamin k: coenzyme for the synthesis of
prothrombin and blood clotting factors in liver
Symptoms:
Bruising from bleeding into skin
Nose bleeding & bleeding gums
Bleeding in stomach
Tarry black stool
In infants, may result in intracranial hemorrhage
Prevention/Treatment
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Vitamin K Deficiency
Deficiency are rare: it is synthesized by the intestinal
bacteria
Hypoprothrombinemia: increased blood coagulation
time
May affect bone growth and mineralization
Malabsorption of lipids lead to vitamin k deficiency
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Drug induced bleeding present in many way, including
(excessive bruising, nose bleeds, heavy menses, GIT
bleeding) bleeding potential by numerous drug such
as (natural drug, anticoagulant or antiplatelet, drug
interaction…)
People with bleeding disorder should check with their
hemophilia center or physician, the instruction before
taking any new herbal drug
Medicines
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Drug that Increase Bleeding Risk
1. Anticoagulant and Antiplatelet: these drugs are used
to prevent or treatment of deep venous thrombosis,
pulmonary embolism, and for prevention of stroke in
atrial fibrillation. Common anticoagulant or
antiplatelet include [aspirin, enoxaparin, heparin,
warfarin]
Aspirin: frequent use aspirin can lead to increase bleeding
Use aspirin to prevent heart attacks or strokes can lead to
increase risk of almost 50% in major bleeding episode especially
GIT bleeding
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Drug that Increase Bleeding Risk
2. Natural Medicine: certain natural medicine and
supplement have been reported to cause bleeding,
either on the own or when used in combination with
other drug for example (Amica, Ginko, Green tea,
Vitamin E …)
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Drug that Increase Bleeding Risk
3. Drug interaction: some drugs that mixed together it
can cause bleeding for example drug – drug
interaction involve antibiotic and antifungals, which
have been reported to increased bleeding used in
combination with drugs that are known to cause
bleeding.
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External Bleeding
Epistaxis:
Relax
Use a tissue to catch the blood
Use thumb and index finger to pinch together the soft
part of your nose
Keep pinching your nose continuously for at least 5
minutes
If your nose is still bleeding, continue squeezing the
nose for another 10 minutes
Cauterization
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Internal Bleeding
The organ is emptied of blood clots
Use (ergometrine) after birth placenta
Use (ergometrine) may effective in control of bleeding
from esophageal varies
Use packing
Surgical ligature(ruptured spleen)
Medication used (hemorrhagic stroke)