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The document describes a BISA ECG device powered by Medtrics that provides 24/7 continuous monitoring. It allows for around-the-clock heart monitoring without interrupting daily activities. In 3 sentences or less, the high-level summary is a device that continuously monitors heart activity remotely.
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Sensors 21-02777
1. Researchers developed a portable ECG device using dry capacitive electrodes and a driven right leg circuit to reject common-mode interference.
2. Simulation and testing of the electronic interface showed high input impedance, suitable common-mode rejection, and readable P, QRS, and T waves.
3. The developed device uses an ESP32 microcontroller to digitize and wirelessly transmit ECG signals, demonstrating the potential for multi-lead wearable ECG monitoring.
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Medical Analytics As a Service (MaaS) provides a RESTful API and machine learning platform for analyzing medical data like ECGs. The platform can recognize 90% of common heart conditions from ECGs, including atrial fibrillation, premature ventricular contractions, and more. It was validated against databases from MIT and the American Heart Association and achieves performance on par with top models. MaaS also offers denoising, heart rate variability metrics, and a portal for ECG processing and analytics.
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This document describes Medical Analytics As a Service (MaaS), which provides APIs, analytics, and a medical database for integrating health data. Key services include ECG analysis that can recognize 90% of common heart conditions using machine learning, and an in-development karyotyping service that aims to automate chromosome classification using deep learning. Metrics provided by ECG analysis include AFib detection accuracy of 94.7% sensitivity and 96.7% PPV compared to MIT databases. The karyotyping service aims to reduce testing time from 2 hours to 30 seconds with 99.7% classification accuracy.
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Radiation therapy techniques like external beam therapy, brachytherapy, and chemotherapy are used to treat cancer. External beam therapy uses machines like linear accelerators and cobalt-60 teletherapy units to deliver high-energy radiation beams to the tumor area. Brachytherapy places radioactive sources directly inside the body. Radiation damages DNA and affects rapidly dividing cells like blood cells. When blood is exposed to radiation, white blood cells are most affected, followed by red blood cells, platelets, and lymphocytes. More research is needed on the effects of radiation on blood components inside the body.
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The VectraplexECG System provides continuous, real-time monitoring of ECG changes suggestive of an acute myocardial infarction (AMI) using a novel Cardiac Electrical Biomarker (CEB) called VectraplexAMI. It requires only 5 electrodes versus the standard 12-lead ECG which uses 10 electrodes. The system analyzes cardiac electrical field data to generate a VectraplexAMI index number that is displayed in real-time, allowing for early detection of potential AMIs. This faster detection could allow for quicker treatment interventions compared to current protocols that rely on serial blood draws to detect cardiac marker changes.
Tractus Matrix IT Flyer
TRACTUS provides medical implant scanning solutions that can scan implants as small as 0.5mm^2 with 30 micron cell sizes. The scanner sends implant identification data to electronic health records and is integrated with major healthcare systems and databases to accurately track utilization for post-market surveillance. TRACTUS solutions simplify unique device identification tracking for hospitals, manufacturers, and regulatory bodies by automating scanning and documentation of medical implants directly into patient medical records.
IOT Based Patient Health Monitoring System Using WIFI
Health is given the extreme importance now a days by each country with the advent of the novel corona virus. So in this aspect, an IOT based patient health monitoring system is the best solution for such an epidemic. With an improvement in technology and miniaturization of sensors, there have been attempts to utilize the new technology in various areas to improve the quality of human life. As a result, this project is an attempt to solve a health care problem currently society is facing covid 19.The main objective of the project was to design for to reduce the corona virus, reduce the components and man power. The framework can be utilized to constantly screen the wellbeing parameters of a patient. The body temperature, heart rate and spo2 can be measured from anyplace on the globe utilizing IOT Internet of Things . IOT monitoring of health helps in preventing the spread of disease as well as to get a proper diagnosis of the state of health, even if the doctor is at far distance. We proposed a nonstop checking and control instrument to screen the patient condition and store the patient information’s in server utilizing Wi Fi Module based remote correspondence. Hence the proposed architecture collects the sensor data through ESP32 microcontroller and relays it to the WIFI where it is processed and analyzed for remote viewing. Feedback actions based on the analyzed data can be sent back to the doctor or guardian through Google sheet and or SMS alerts in case of any emergencies. Marupuri Usha Priya | Muthu Pandi K | Priya S | Dr. Kishore Kumar Arjunsingh "IOT Based Patient Health Monitoring System Using WIFI" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45143.pdf Paper URL: https://www.ijtsrd.com/engineering/electronics-and-communication-engineering/45143/iot-based-patient-health-monitoring-system-using-wifi/marupuri-usha-priya
Sensors 21-02777
1. Researchers developed a portable ECG device using dry capacitive electrodes and a driven right leg circuit to reject common-mode interference.
2. Simulation and testing of the electronic interface showed high input impedance, suitable common-mode rejection, and readable P, QRS, and T waves.
3. The developed device uses an ESP32 microcontroller to digitize and wirelessly transmit ECG signals, demonstrating the potential for multi-lead wearable ECG monitoring.
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This document discusses an ECG analysis partnership that can recognize 90% of common heart diseases from ECG readings. It describes several conditions the analysis can detect, including atrial fibrillation, premature arterial contractions, premature ventricular contractions, and sinus bradycardia. The analysis has advantages of being validated against several databases, performing as well or better than other models for arrhythmia detection, allowing comprehensive heart disease detection across multiple conditions, and working with all 12 leads of ECG data.
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Medical Analytics As a Service (MaaS) provides a RESTful API and machine learning platform for analyzing medical data like ECGs. The platform can recognize 90% of common heart conditions from ECGs, including atrial fibrillation, premature ventricular contractions, and more. It was validated against databases from MIT and the American Heart Association and achieves performance on par with top models. MaaS also offers denoising, heart rate variability metrics, and a portal for ECG processing and analytics.
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This document describes Medical Analytics As a Service (MaaS), which provides APIs, analytics, and a medical database for integrating health data. Key services include ECG analysis that can recognize 90% of common heart conditions using machine learning, and an in-development karyotyping service that aims to automate chromosome classification using deep learning. Metrics provided by ECG analysis include AFib detection accuracy of 94.7% sensitivity and 96.7% PPV compared to MIT databases. The karyotyping service aims to reduce testing time from 2 hours to 30 seconds with 99.7% classification accuracy.
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The document summarizes Medtrics' Medical Analytics as a Service (MaaS) platform. The platform provides APIs and machine learning models to analyze ECG and karyotyping data. For ECG analysis, it can recognize 90% of common heart conditions from ECGs, including atrial fibrillation, premature ventricular contractions, and more. It has been validated against standard databases and achieves high accuracy. For karyotyping, it aims to automate the analysis through deep learning to reduce human error, cost, and processing time from hours to seconds. Roadmaps are provided for further improving the capabilities of ECG and karyotyping analysis over multiple phases.
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Regulatory Affairs
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M.pharm - 1st year .The Nervous and Chemical Regulation of Respiration
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
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9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
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Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
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Patellar Instability: Diagnosis Management
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
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Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
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Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort. Top Travel Vaccinations in Manchester
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This guideline is directed principally toward new Molecular Entities that are
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The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
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