Bioenergetics, or the flow of energy in a biological system, concerns primarily the conversion of macronutrients— carbohydrate, protein, and fats, which contain chemical energy—into biologically usable forms of energy. It is the breakdown of the chemical bonds in these macronutrients that provides the energy necessary to perform biological work. Catabolism (exergonic)Anabolism (endergonic) The breakdown of large molecules into smaller molecules, associated with the release of energy, is termed catabolism. The synthesis of larger molecules from smaller molecules can be accomplished using the energy released from catabolic reactions; this building-up process is termed anabolism. The breakdown of protein into amino acids is an example of catabolism, while the formation of protein from amino acids is an anabolic process. Exergonic reactions Endergonic reactions Exergonic reactions are energy-releasing reactions and are generally catabolic. Endergonic reactions require energy and include anabolic processes and the contraction of muscle. Metabolism is the total of all the catabolic or exergonic and anabolic or endergonic reactions in a biological system Adenosine triphosphate ATP Energy derived from catabolic or exergonic reactions is used to drive anabolic or endergonic reactions through an intermediate molecule, adenosine triphosphate (ATP). Adenosine triphosphate allows the transfer of energy from exergonic to endergonic reactions. Without an adequate supply of ATP, muscular activity and muscle growth would not be possible.