Bilberry is a shrub related to blueberries found in parts of Europe and Asia. Its berries contain anthocyanosides, a flavonoid with antioxidant properties. Claims have been made that bilberry improves night vision and protects against cataracts and glaucoma, but evidence is mixed. While some studies found benefits, others found no effect. Further research is still needed, including studies to identify mechanisms of action and large-scale clinical trials, before health claims can be verified.
Justin presented this slide show on July 20, 2011, at the SURP symposium to celebrate the summer research program. The exciting slide is slide 13 that shows significant improvement in survival at the 2 week mark.
Neuroprotective Effects of Withania somnifera Dunn. in Hippocampal Sub-region...daburmediclub
Clinical Study by Dabur Mediclub- Neuroprotective Effects of Withania somnifera Dunn. in Hippocampal Sub-regions of Female Albino Rat.
For more details visit:http://www.daburmediclub.com/clinicalreport/reports.aspx
Justin presented this slide show on July 20, 2011, at the SURP symposium to celebrate the summer research program. The exciting slide is slide 13 that shows significant improvement in survival at the 2 week mark.
Neuroprotective Effects of Withania somnifera Dunn. in Hippocampal Sub-region...daburmediclub
Clinical Study by Dabur Mediclub- Neuroprotective Effects of Withania somnifera Dunn. in Hippocampal Sub-regions of Female Albino Rat.
For more details visit:http://www.daburmediclub.com/clinicalreport/reports.aspx
To conserve endangered medicinal plant species, Exacum bicolor Roxb. (Gentianaceae), an efficient micropropagation protocol was developed by using nodal segments for axillary shoot proliferation. Higher multiplication rate was achieved with 78% on MS medium supplemented with growth hormones, IBA and GA3 at 1.5 mg/l and 0.5 mg/l respectively. Rooting was more effective with 75% of the node derived in vitro shoots in MS basal medium with the auxins, IBA and NAA at 1.0 mg/l and 0.5 mg/l respectively. Using the hardening medium containing garden soil, sand and vermiculate in the ratio of 1:1:1 by volume, regenerated plantlets could be successfully acclimatized at a rate of 80 % survivability.
Hepatotoxicity and Nephrotoxicity Studies of Ethanol Extracts of Annona Muric...Premier Publishers
The study determined the effects of administration of ethanol extracts of Annona muricata leaves (AML) and Fagara zanthoxyloide roots (FZR) on liver and kidney indices in zidovudine (ZDV)-induced Wistar rats. Animals were grouped into five (5); group 1 served as normal control, groups 2-5 were induced with 100g/mlZDV/Kgbw and group 3 treated with 35IU/Kgbw of erythropoietin, group 4 with 4.5g/mlAML/Kgbw and group 5 with 3.8g/mlFZR/Kgbw for six weeks. Serum liver enzymes, other biochemicals (total protein, albumin, globulin, bilirubin, urea and creatinine), organ weights and histological examination were used to assess the impact on the liver and kidney using standard methods. A significant elevation (p≤0.05) in the activities of serum liver enzymes and bilirubin accompanied by a significant decrease (p≤0.05) in the other biochemicals were observed in group 2. Treatment with extracts resulted in a modulation of the induced effects of ZDV causing a significant decrease in the serum liver enzymes, bilirubin and increase in the total protein, albumin and globulin concentrations. Histology of the liver showed altered architecture, blood vessel congestion and necrosis; while the kidneys were hypoplastic with signs of swelling (group 2) which was gradually reverted on treatment with extracts. The study suggests that extracts of AML and FZR may confer some degree of protection to the liver and kidney.
Dr. Ravi S Pandey-Resume for Assistant Professor/ Research Scientist in Bioch...Dr. Swami Gyan Prakash
Dear Member of Recruiter Committee,
I am writing this letter for a position of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology. In brief, I am PhD in Medicinal Biochemistry and completed several successful projects as a Postdoctoral Scientist in different discipline of Biochemistry like Molecular Biology of Aging, Alternative splicing in human diseases, Epigenetic regulation in liver and breast cancer from India and USA. I came back to India in April 2010 and worked as a CSIR-Pool Scientist in the area of chromatin remodeling in breast cancer. My tenure has been completed recently. Thus, I am looking for a faculty position of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology.
I am highly interested to trend the graduate students in Biochemistry, Biotechnology and Molecular Biology. Besides, I am very much motivated to lead projects in the area of Cancer Biology. Thus, I respectfully submit this letter of application, for I believe my experiences and commitment for teaching and research make me well qualified to meet the needs of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology.
I am well acquainted with the molecular techniques associated with DNA, RNA and proteins research. Besides, I am expertise in planning and execution of experiments, mentoring PhD students, interpreting data, as well as writing and data preparation for manuscript publication. During my doctorate and post doctorate time, I taught graduate and postgraduate students on behalf of my mentors. I am well organized, goal oriented; self motivated research scientist and committed to train the student in area of Clinical Biochemistry and Molecular Biology along with lead research work in the area of Cancer Biology. I would appreciate for an interview opportunity to discuss about my background, qualification and expertise that may fit for the position.
Molecular Biologist Academic CV for Industry or Private Sector Consideration Sirie Godshalk
Molecular Biologist with over thirteen years of hands-on research experience, impactful writer and presenter, dynamic leader and enthusiastic team player with an eye for great ideas and a passion to move science in new directions seeks challenging opportunities beyond the bench.
Deciphering barcode splits in morphologically cryptic species of tropical lepidopters through alternative loci and next-generation sequencing approaches.
“Periodontal Regeneration- New Vistas”- Guest lecture as a part of Dr NTRUHS Zonal CDE programme at SVS Institute of Dental Sciences, Mahabubnagar, India on 12/3/2013 and at Meghna Dental College, Nizamabad, India on 31/7/2013.
¿Cómo funciona?
Según científicos del Instituto Himalaya de Ciencias Médicas, la pérdida de audición ocurre cuando el tímpano pierde elasticidad debido a la inflamación desencadenada por el sistema inmunológico del cuerpo cuando se expone a una nueva amenaza.
Esta nueva amenaza proviene de productos químicos médicos tóxicos (u ototoxinas) que desafortunadamente pueden ser Se encuentra en la mayoría de los medicamentos recetados diariamente por los médicos sin saberlo.
Al abordar la causa raíz de la pérdida auditiva, SonoFit actúa como un "vendaje en el oído interno", calmante y ayudando al tímpano a recuperarse, mientras lo protege de daños futuros.
To conserve endangered medicinal plant species, Exacum bicolor Roxb. (Gentianaceae), an efficient micropropagation protocol was developed by using nodal segments for axillary shoot proliferation. Higher multiplication rate was achieved with 78% on MS medium supplemented with growth hormones, IBA and GA3 at 1.5 mg/l and 0.5 mg/l respectively. Rooting was more effective with 75% of the node derived in vitro shoots in MS basal medium with the auxins, IBA and NAA at 1.0 mg/l and 0.5 mg/l respectively. Using the hardening medium containing garden soil, sand and vermiculate in the ratio of 1:1:1 by volume, regenerated plantlets could be successfully acclimatized at a rate of 80 % survivability.
Hepatotoxicity and Nephrotoxicity Studies of Ethanol Extracts of Annona Muric...Premier Publishers
The study determined the effects of administration of ethanol extracts of Annona muricata leaves (AML) and Fagara zanthoxyloide roots (FZR) on liver and kidney indices in zidovudine (ZDV)-induced Wistar rats. Animals were grouped into five (5); group 1 served as normal control, groups 2-5 were induced with 100g/mlZDV/Kgbw and group 3 treated with 35IU/Kgbw of erythropoietin, group 4 with 4.5g/mlAML/Kgbw and group 5 with 3.8g/mlFZR/Kgbw for six weeks. Serum liver enzymes, other biochemicals (total protein, albumin, globulin, bilirubin, urea and creatinine), organ weights and histological examination were used to assess the impact on the liver and kidney using standard methods. A significant elevation (p≤0.05) in the activities of serum liver enzymes and bilirubin accompanied by a significant decrease (p≤0.05) in the other biochemicals were observed in group 2. Treatment with extracts resulted in a modulation of the induced effects of ZDV causing a significant decrease in the serum liver enzymes, bilirubin and increase in the total protein, albumin and globulin concentrations. Histology of the liver showed altered architecture, blood vessel congestion and necrosis; while the kidneys were hypoplastic with signs of swelling (group 2) which was gradually reverted on treatment with extracts. The study suggests that extracts of AML and FZR may confer some degree of protection to the liver and kidney.
Dr. Ravi S Pandey-Resume for Assistant Professor/ Research Scientist in Bioch...Dr. Swami Gyan Prakash
Dear Member of Recruiter Committee,
I am writing this letter for a position of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology. In brief, I am PhD in Medicinal Biochemistry and completed several successful projects as a Postdoctoral Scientist in different discipline of Biochemistry like Molecular Biology of Aging, Alternative splicing in human diseases, Epigenetic regulation in liver and breast cancer from India and USA. I came back to India in April 2010 and worked as a CSIR-Pool Scientist in the area of chromatin remodeling in breast cancer. My tenure has been completed recently. Thus, I am looking for a faculty position of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology.
I am highly interested to trend the graduate students in Biochemistry, Biotechnology and Molecular Biology. Besides, I am very much motivated to lead projects in the area of Cancer Biology. Thus, I respectfully submit this letter of application, for I believe my experiences and commitment for teaching and research make me well qualified to meet the needs of Assistant Professor/ Research Scientist in Biochemistry, Clinical-Biochemistry, Biotechnology and Molecular Biology.
I am well acquainted with the molecular techniques associated with DNA, RNA and proteins research. Besides, I am expertise in planning and execution of experiments, mentoring PhD students, interpreting data, as well as writing and data preparation for manuscript publication. During my doctorate and post doctorate time, I taught graduate and postgraduate students on behalf of my mentors. I am well organized, goal oriented; self motivated research scientist and committed to train the student in area of Clinical Biochemistry and Molecular Biology along with lead research work in the area of Cancer Biology. I would appreciate for an interview opportunity to discuss about my background, qualification and expertise that may fit for the position.
Molecular Biologist Academic CV for Industry or Private Sector Consideration Sirie Godshalk
Molecular Biologist with over thirteen years of hands-on research experience, impactful writer and presenter, dynamic leader and enthusiastic team player with an eye for great ideas and a passion to move science in new directions seeks challenging opportunities beyond the bench.
Deciphering barcode splits in morphologically cryptic species of tropical lepidopters through alternative loci and next-generation sequencing approaches.
“Periodontal Regeneration- New Vistas”- Guest lecture as a part of Dr NTRUHS Zonal CDE programme at SVS Institute of Dental Sciences, Mahabubnagar, India on 12/3/2013 and at Meghna Dental College, Nizamabad, India on 31/7/2013.
¿Cómo funciona?
Según científicos del Instituto Himalaya de Ciencias Médicas, la pérdida de audición ocurre cuando el tímpano pierde elasticidad debido a la inflamación desencadenada por el sistema inmunológico del cuerpo cuando se expone a una nueva amenaza.
Esta nueva amenaza proviene de productos químicos médicos tóxicos (u ototoxinas) que desafortunadamente pueden ser Se encuentra en la mayoría de los medicamentos recetados diariamente por los médicos sin saberlo.
Al abordar la causa raíz de la pérdida auditiva, SonoFit actúa como un "vendaje en el oído interno", calmante y ayudando al tímpano a recuperarse, mientras lo protege de daños futuros.
Sonofit
This new threat comes from toxic medicinal chemicals (or ototoxins) that unfortunately can be found in most of the medications that doctors unknowingly prescribe on a daily basis.
By addressing the underlying cause of hearing loss, SonoFit acts like an "inner ear bandage," soothing the eardrum and protecting it from future damage.
Altissimi G, Colizza A, Cianfrone G, et al. Hearing loss, tinnitus, dizziness, and vertigo: an updated guide. Eur Rev Med Pharmacol Sci. 2020 Aug 1;24(15):7946-52.
Epiphone. Ototoxicity: Which drugs can cause hearing loss or tinnitus [Internet]. Epiphone. Ampliphone;
READ MORE
https://healthcare615.blogspot.com/2023/09/sonofit-sonofit-drops.html
31.Medicinal uses of poisonous fishes..pdfsalehaasawer
Science makes new discoveries everyday that advance human health and well being. According to new researches fish poison have huge medical importance. These poisons are examined in several animal models.
In recognition of foot health month, the status of tea tree oil as an antimicrobial agent is reviewed. Tea tree oil shows great promise as an antifungal and antibacterial product. This includes topical infections of foot and toe nails.
The Value of Conducting Post-Marketing Clinical Research On Marketing Strategy Development
Nutraceutical Medical Research, LLC
By: Latesha Richards, Marketing Coordinator
Post Marketing Clinical Research & Marketing Strategy
Bilberry And Vision March 2010
1. NMR News: Volume 3, Issue 3, March 2010
To See or Not to See: The Science Behind Bilberry
By: Charles Spielholz, Ph.D.
B
ilberry (genus Vaccinium, several different (2,3). In addition, a mechanism of action has not
species with Vaccinium myrtillus being the been established for how bilberry may be
most common) is shrub that bears fruit. improving night vision. Clearly, additional research
Related to blueberries, the plant is found in establishing both a mechanism of action and
England, mainland Europe, Scandinavia, Turkey, employing large scale clinical trials is required
and Russia. Because bilberry does not grow easily, before a role can be established for bilberry in night
it is not cultivated to any significant extent. Like vision.
other edible berries, bilberry fruit can be eaten
directly or made into jams, jellies, pie fillings, juice, There has been one report suggesting that
or flavors for ice bilberry flavonoids
creams, sorbets and provide improvements in
other desserts. The intraocular pressure
berries of bilberry resulting from glaucoma
have been associated (4). However, there has
with several health been no follow-up
claims regarding evidence in the medical
vision. Therefore a literature that confirms
brief examination of this 1985 report.
these claims will be Reports in the
made. literature suggest that a
Consumption diet high in
of the bilberry plant has been associated with anthocyanosides slowed the development of
improvements in vision, protection against cataracts in laboratory rats (5) and propose a
glaucoma and the prevention of cataracts. reduction of aldose reductase enzyme activity as a
Anthocyanosides, a flavonoid pigment with possible mechanism for this event (6). However, no
antioxidant properties found in bilberries, is the significant follow-up research has been reported in
component of pharmacological interest. Claims the medical literature since these reports appeared
regarding improvement in vision center on in the mid-1980s and there have been no reports
improved night vision. However, studies are mixed that tested bilberry extract directly in a clinical trial
with one clinical trial indicating an improvement in in the United States.
night vision (1) and others indicating no effect
1
2. NMR News: Volume 3, Issue 3, March 2010
A few reports in the literature indicate that 4) Caselli L. 1985. Clinical and electroretinographic
bilberry may protect the retina against damage from studies on activity of anthocyanosides. Arch Med Int. 37:
oxidation (7-9), diabetes (10), and angiogenesis 29-35.
(11). There have also been reports concerning the 5) Hess HH, Knapka JJ, Newsome DA, Westney IV,
significance of diet on inherited retinal dystrophy in Wartofsky L. 1985. Dietary prevention of cataracts in the
the rat (12) thus suggesting that diet may play a role pink-eyed RCS rat. Lab Anim Sci. 35:47-53.
in the normal health and functioning of the retina.
One report suggested that since bilberry extracts, as 6) Chaudry PS, Cambera J, Juliana HR, Varma SD.
well as other antioxidants, reduced damage to DNA 1983. Inhibition of human lens aldose reductase by
flavonoids, sunindac and indomethacin. Biochem
by a certain epoxide (A2E-epoxide) in retinal
Pharmacol 32:1995-1998.
pigment epithelial cells maintained in the laboratory
(8) that it is perhaps not impossible that damage to 7) Jang YP, Zhou J, Nakanishi K, Sparrow JR. 2005.
the retina from light induced epoxidation may be Anthocyanins protect against A2E photooxidation and
due to a deficiency of antioxidants (8). If further membrane permeabilization in retinal pigment epithelial
research proves this relationship to be true, then cells. Photochem Phgotobiol 81:529-536.
dietary approaches to retinal diseases, that include
8) Sparrow JR, Vollmer-Snarr HR, Zhou J, Jang YP,
bilberry, will be worth exploring. Jockusch S, Itagaki Y, Nakanishi K. 2003. A2E-epoxides
damage DNA in retinal pigment epithelial cells. J Biol
Evidence indicating a role for bilberry,
Chem. 278:18207-18213.
either as whole berries or an extract, is still in the
early stages. Additional research, including 9) Matsunaga N, Imai S, Inokuchi Y, Shimazawa M,
laboratory bench research to elucidate a mechanism Yokota S, Araki Y, Hara H. 2009. Bilberry and its main
of action, and clinical trials, to show a benefit to constituents have neuroprotctive effects against retinal
vision in humans, are required to unambiguously neuronal damage in vitro and in vivo. Mol Nutr Food
verify health claims regarding bilberry and eye Res. 53: 869-877.
health. 10) Chung HK, Choi SM, Ahn BO, Kwak HH, Kim JH,
Kim WB. 2005. Efficacy of troxerutin on
References
streptozoctocin-induced rat model in the early stage of
1) Sala D, Rolando, M, Rossi, PL, Pissarello L. 1979. diabetic retoniopathy. Arzneimittelforschuhng 55:573-
Effect of anthocyanosides on visual performance at low 580.
illumination. Minerva Oftalmol. 91:283-285.
11) Matsunaga N, Chikaraisshi Y, Shimazawa M,
2) Muth ER, Laurent JM, Jasper P. 2000. The effect of Yokota S, Hara H. 2007. Vaccinium myrtillus (Bilberry)
bilberry supplementation on night visual acuity and extracts reduce angiogenesis in vitro and in vivo. Evid
contrast sensitivity. Altern Med Rev. 5:164-173. Based Complement Alernat Med. 7:47-56.
3) Zadok D, Levy Y, Glovinsky Y. 1999. The effect of 12) Pautler EL, Ennis SR. 1984. The effect of diet on
anthocyanosides in a multiple oral dose on night vision. inherited retinal dystrophy in the rat. Current Eye Res.
Eye (Lond). 13:734-736. 3:1221-1224.
2