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Basic Components of Food
& Metabolism
• Presented By –
• Prof.Dr.R.R.Deshpande (M.D
in Ayurvdic Medicine & M.D.
in Ayurvedic Physiology)
• www.ayurvedicfriend.com
• Mobile – 922 68 10 630
• professordeshpande@gmail.
com
8/3/2016 Prof.Dr.R.R.Deshpande 1
8/3/2016 Prof.Dr.R.R.Deshpande 2
8/3/2016 Prof.Dr.R.R.Deshpande 2
Sharir Kriya -- Paper I –
Part B –Point f
• Presented By –
• Prof.Dr.R.R.Deshpande (M.D in Ayurvdic
Medicine & M.D. in Ayurvedic Physiology)
• www.ayurvedicfriend.com
• Mobile – 922 68 10 630
• mailme.drrrdeshpande@rediffmail.com
Sharir Kriya Paper 1-Part B –Set 2
• Presented By –
• Dr.R.R.Deshpande
• Prof & HOD
• CARC ,Pune 44
8/3/2016 Prof.Dr.R.R.Deshpande 3
8/3/2016 Prof.Dr.R.R.Deshpande 4
8/3/2016 Prof.Dr.R.R.Deshpande 4
Sharir Kriya Hand Book –
1st to last year BAMS
• Best for Fast Revision
• Paper 1,Paper 2
• Practicals
• Instruments
• Histology
• IMP Schlok
• All basics of
Dodha,Dhatu & Mala
8/3/2016 Prof.Dr.R.R.Deshpande 5
8/3/2016 Prof.Dr.R.R.Deshpande 5
Sharikriya Paper Practical Book
• As per Very New
Syllabus formed By
CCIM IN 2012
• Ayurvedic Practicals like
Prakruti,sara,Agni
• Modern Haematological
Practicals
• CNS & CVS Examination
8/3/2016 Prof.Dr.R.R.Deshpande 6
8/3/2016 Prof.Dr.R.R.Deshpande 6
Clinical Examination
• Systemic Examination of
8 systems
• Ayurvedic Srotas
Examination
• Clinical significance of
Lab Tests &
Radiology,USG,2D Echo
8/3/2016 Prof.Dr.R.R.Deshpande 7
8/3/2016 Prof.Dr.R.R.Deshpande 7
Sharir Kriya Paper 1
• Book in English
• Total CCIM Syllabus
covered
• Chaukhamba Sanskrit
Pratisthan Publication
• Popular Nationwide &
In Germany also
• Dosha & Prakruti
8/3/2016 Prof.Dr.R.R.Deshpande 8
8/3/2016 Prof.Dr.R.R.Deshpande 8
Sharir Kriya Paper 2
• Book in English
• Total CCIM Syllabus
covered
• Chaukhamba Sanskrit
Pratisthan Publication
• Popular Nationwide &
In Germany also
• Dhatu,Mala
8/3/2016 Prof.Dr.R.R.Deshpande 9
Prof.Dr.Deshpande’s
Popular Links on Internet
• Just Start Internet on Desk top or Lap top or
on your mobile . Copy Following Link & Paste
as Web address –URL
• http://www.youtube.com/user/deshpande19
59
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• http://www.mixcloud.com/jamdadey/
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Prof.Dr.Deshpande’s
Popular Links on Internet
• Just Start Internet on Desk top or Lap top or
on your mobile . Copy Following Link & Paste
as Web address –URL
• http://professordeshpande.blogspot.in
• http://professordrdeshpande.blogspot.in/
• http://www.mixcloud.com/rajendra-
deshpande
• https://soundcloud.com/professor-deshpande
8/3/2016 Prof.Dr.R.R.Deshpande 10
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Acid Base Balance
• Acid Base balance is very important for the
homeostasis.
• An acid is the proton donor means which liberates
hydrogen ions.
• A base is the proton acceptor means which accepts
hydrogen ions.
• In the human body the concentration of free
hydrogen ion is maintained same at the level of 7. 4
pH.
Acid Base Balance
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What is pH?
• pH means hydrogen ion concentration.
• Increased in hydrogen ion concentration decreases
the pH (Less than 7), which is called as acidosis.
• Reduction in hydrogen ion conc. Increases the pH
(Greater than 7) which is called as alkalosis.
• ECF, in healthy person has a pH range from 7. 38 to
7. 42.
Acid Base Balance
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Measurement of Acid Base status
• Acid base status of ECF is determined by
Henderson - Hasselbalch equation
• pH = pK + log (HCO3 / CO2)
• pH of plasma is more important this is
determined by pH meter.
• pH of arterial blood is an indirect
measurement of H+ ion concentration & it
indicates the balance of CO2 & HCO - 3.
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Regulation of Acid base balance
• Human body has a constant fear of acidosis.
•
• 2 types of acids are constantly produced in the body.
• Volatile acids are derived from CO2 (which is
produced during metabolism of carbohydrates &
fats)
• Non - volatile acids - are produced during the
metabolism of proteins.
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Mechanisms to regulate
Acid Base balance
• Acid base buffer system (which binds free
hydrogen ions)
• Respiratory mechanism (which eliminates
CO2)
• Renal mechanism (which excretes H+ &
preserve HCO3 -).
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Acid - Base buffer system
• This is the fastest mechanism & resettled the
pH within seconds.
• 3 types of buffer system are ----
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I) Bi - carbonate buffer system
• This is present in plasma of ECF, consist of
carbonic acid (H2CO3) & a salt sodium bi -
carbonate (NaHCO3).
• This system prevents the fall of pH in a fluid to
which a strong acid like HCl is added & also
prevents increase in pH when strong base like
NaOH is added
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I) Bi - carbonate buffer system
• This buffer system is not powerful, but it plays
an important role in maintaining the pH of
body fluids than the other buffer systems.
• This system works effectively because of 2
regulatory mechanisms (conc. of HCO3- is
regulated by kidneys & conc. of CO2 is
regulated by respiratory system.)
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II) Phosphate buffer system
• This system has a weak acid that is sodium di
hydrogen phosphate (NaH2PO4) a base Di -
sodium hydrogen phosphate(Na2HPO4).
•
• This system is useful in ICF, in RBC. This
system is more powerful than bicarbonate
buffer system.
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III) Protein buffer system
• Is present in plasma as well as in RBCs.
• Haemoglobin is the most effective protein
buffer in the blood, Hb prevents fall in pH
when more & more CO2 enters in to the
capillaries
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2) Acid base balance
By respiratory system
• Lungs maintain acid base balance by removing
CO2.
• When metabolic activity increase more CO2 is
produced in the tissue & increase in H+ ion
concentration (CO2 + H2O - H2CO3 - H+ &
HCO3 ions) due to increase in H+
concentration hyper ventilation takes place &
excess of CO2 is removed from the body.
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3) Acid base balance
By Renal system
• During urine formation process ----
• There is secretion of H+ &
• Retention of HCO3–
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Applied part of
Acid Base balance
• 1) Acidosis –
• This is increase in H+ ion concentration & pH
becomes less than 6
• This occurs due to increase in Pco2 in arterial
blood & decrease in HCO3– .
Applied part of
Acid Base balance
• 2) Alkolosis –
• This is decrease in H+ conc. &
• Increase in pH that is greater than 7.
• Acid base disturbances - They are mainly 2
types
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1. Respiratory Acidosis
• PCO2 in arterial blood = 40 mmHg. Acidosis
takes place when it is above 60mmHg.
• Common causes of acidosis are broncho
spasm, emphysema, pneumonia, cerebral
trauma, paralysis of respiratory muscle,
hypoventilation or decrease ventilation is the
main pathology in acidosis.
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2. Respiratory Alkalosis
• This occurs when PCO2 is less than 20 mmHg.
• Hyperventilation is the main pathology for
loss of excess CO2.
• The main causes of hyper ventilation in
respiratory alkalosis are high altitude, severe
anaemia, cerebral disturbances, pulmonary
oedema, psychological trauma.
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3. Metabolic Acidosis
• This is due to excess accumulation of like
lactic acid, ketoacidosis & uric acid.
• Main causes are lactic acidosis in circulatory
shock, ketoacidosis in DM, Uric acidosis in
renal failure
Metabolic Acidosis
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4. Metabolic Alkalosis
• This is cause by loss of excess H+ ion &
increase HCO3– conc.
• The common causes are diuretic drugs,
vomiting, Cushing’s syndrome.
Metabolic Alkalosis
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Water & Electrolyte Balance
• Regulation of Water balance
• Water content of the blood has always a
communication with interstitial fluid.
• This helps in the water regulation, skin also
regulates water quantity & electrolyte balance
by excretion of water & salts through sweat.
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Fluid compartments
in the Human Body
• Body fluid consist of water & dissolved solutes
that is electrolyte.
• This fluid has in a range of 55 - 60% of total
body weight.
Fluid compartments
in the Human Body
• For the healthy condition homeostasis of body
fluid is essential.
• 2/3rd of the body fluid is intracellular (ICF)
• 1/3rd is extracellular (ECF).
• 80% of ECF is interstitial fluid & 20% is blood
plasma
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Fluid compartments
in the Human Body
• Fluid moves from one compartment to another but
keeping the same proportion as mentioned above.
• As water is main part of body fluid, fluid balance
means water balance.
• Electrolytes (Inorganic compounds which dissociate
in to ions) are main solutes in body fluid so, fluid
balance means also electrolyte balance.
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Body water
• Infants have water content, up to 75% of body
weight.
• This amount decreases with age as adipose
tissue contains no water, fat people have less
amount of water than lean people.
• In male water is 60% of body weight & in
female it is 55%.
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Water gain & Water loss
• Water gain
• 1600 ml through ingested liquids (beverages)
•
• 700 ml through ingested food
• 200 ml through metabolic water.
• Total gain is 2500ml.
Water gain & Water loss
• Water loss
• 1500 ml of water loss takes place through kidneys
• 600ml through skin
• 300 ml through lungs
• 200 ml through digestive system
• Total water loss = 2500ml.
• Usually water loss is same as water gain. This is
homeostasis
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Water Gain & Water Loss
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Regulation of fluid gain
• This is done mainly through drinking more or
less fluid. Regulation takes place as follows –
• Dehydration takes place when water loss is
more than water gain (In the condition like
watery diarrhoea, vomiting, fever, diuretics)
Dehydration stimulates thirst.
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Regulation of fluid gain
• When production of saliva decreases it causes
dryness of the mouth.
• When blood volume decreases, hypotension
develops, which stimulates rennin -
angiotensin mechanism
• Angiotensin 2 too stimulates thirst centre.
• Naturally person drinks more water & normal
fluid volume is restored
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Regulation of fluid loss
• This is controlled by anti - diuretic hormone
(ADH) Aldosteron & atrial natriuretic peptide
(ANP)
• Water over load increases blood pressure &
the rate of glomerular filtration increase so
more water is loss in the urine.
Water Balance
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Caution
• 1) If repeated enemas are given in young
children, can increase the risk of fluid &
electrolyte imbalances.
• 2) Why isotonic solution is given? - usually tap
water is hypotonic & commercially prepaid
solutions are hypertonic. Both this type of
solutions can cause rapid fluid & electrolyte
shift.
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About Electrolytes
• Definition –
• Inorganic substance which dissociate in to
ion, in solutions is called an electrolyte
• Because now this solution can conduct an
electric current
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About Electrolytes
• Electrolytes dissociates in to cations
(Positively charged ions) & anions (negatively
charge ions)
• Acids, bases & salts are electrolytes, unites
which express the total number of particles in
a given volume of solution are expressed as
milli osmoles per litre
• Electrolytes have a greater effect on osmosis
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Comparison of Electrolytes in different
fluid compartments
• In ECF - Major cations is Na+ & major anions
Cl- & HCO3-
• In ICF - Major cat ions is K+ & major anions
are proteins & phosphates (ATP).
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About different Ions
• 1. Sodium ions are more in extracellular fluid.
• They help in impulse transmission, muscle
contraction & fluid & electrolyte balance.
• Sodium level is controlled by Aldosteron
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About different Ions
• 2. Potassium ions are more in intracellular
fluid.
• They are responsible for fluid volume, impulse
conduction, muscle contraction & pH
regulation.
• Potassium level is controlled by Aldosteron.
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About different Ions
• 3. Calcium –
• Ca++ is extracellular cation.
• This is responsible for blood clotting,
neurotransmitter release, contraction of
muscle.
• Level is maintained by 2 hormones as
parathyroid hormone & calcitonin
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About different Ions
• 4. Magnesium ions –
• This is intracellular cations.( Positive Charge)
• They are co - factors in several enzyme
systems.
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About different Ions
• 5. Chlorides are major extracellular anions
they are helpful for regulating osmotic
pressure & forming HCl
• Level is indirectly controlled by Aldosteron
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About different Ions
• 6. Bi - carbonate ions –
• Present in extracellular fluid
• They help as important buffer in plasma.
About different Ions
• 7. Phosphate ions –
• They are intracellular anions & there salts are
structural components of bones & teeth
• They are useful for synthesis of nucleic acids &
ATP. Level is controlled by PTH & CT
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Imbalance in Electrolytes
• 1) Sodium imbalance
• Hyponatremia occurs in the conditions like vomiting,
diarrhoea, during diuretic therapy, burn, excessive
sweating.
• Clinical features are muscle weakness dizziness,
headache, hypotension, tachycardia, shock & some
times confusion, stupor & coma.
Sodium Imbalance
• Hypernatremia occurs with water loss or
excessive sodium by eating salted
snaks,pickles,Papad etc
• Clinical features are excessive thirst , fatigue
hypertension, restlessness & some times
coma.
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2) Chloride imbalance
• Hypochloremia –
• Caused by vomiting, diarrhoea, excess dose of
lasix
• Clinical features are muscle spasm (calf pain)
depressed respiration & some times coma.
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3) Potassium imbalance
• Hypokalemia occurs in vomiting, diarrhoea, diuretics
& less sodium intake
• Clinical features are cramps, fatigue, flaccid
paralysis, nausea, vomiting, mental confusion,
shallow respiration, ECG changes (prolonged QT
interval & flattening of T wave)
• To prevent hypokalemia recently potassium sparing
diuretics are used like Tab. Amiphru Or Tab.
Lacilactone
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3) Potassium imbalance
• Hyperkalemia –
• Features are irritability, abdominal cramps,
diarrhoea, weakness of lower limbs, burning
or prickling sensation
• In extreme case due to fibrillation of the heart
patient can die.
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4) Calcium imbalance
• Hypocalcemia can occur --
• Due to reduced calcium intake,
hypoparathyroidism, increased calcium loss in
old age
• Clinical features are Tetany, muscle cramp,
convulsions, tingling numbness, bone
fractures, osteoporosis.
4) Calcium imbalance
• Hypercalcemia –
• Due to over dose of calcium tablets
• Features are lethargy, nausea, itching, bone
pain, depression.
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5) Phosphate imbalance
• Hypophosphatemia –
• Occurs due to increased urinary loss, intestinal
obstruction
• Features are chest & muscle pain, tingling
numbness, susceptibility to infection.
5) Phosphate imbalance
• Hyperphosphatemia –
• Occrs due to renal failure too excrete excess
phosphate
• Features are nausea, tetany, hyperactive
reflexes
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6) Magnesium imbalance
• Hypomagnesemia –
• Occurs due to diarrhoea, alcoholism, malnutrition,
DM, diuretic drugs, excessive lactation
• Features are weakness, tetany, nausea, cardiac
arrhythmia.
6) Magnesium imbalance
• Hypermagnesemia –
• Occurs due to renal failure or increased
intake of magnesium containing antacids,
acute diabetic ketoacidosis.
• Features are nausea, hypotension, altered
mental functioning.
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Basic components of food
• Nutrients in food
• 1) Nutrients
• The chemical components of food which when
consumed, nourish the body & regulate the
various functions of the body are called
nutrients.
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2) Nutrients present in the food
(Proximal principles of food)
• 1) Carbohydrates
• 2) Proteins
• 3) Fats
• 4) Vitamins
• 5) Minerals
• 6) Water
Sources of Proteins,
Carbohydrates & Fats
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1) Carbohydrates
• Carbohydrates are organic compounds containing
carbon (C), hydrogen (H) & oxygen (O).
• Carbohydrates are the most abundant organic
compounds that are found in the living world.
• Carbohydrates are synthesized by green plants by a
process called photosynthesis.
• One gram of carbohydrate provides approximately 4
calories of energy.
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Plant sources of dietary
carbohydrates
• Cereals & millets like wheat, rice, maize, jowar,
bajra, ragi etc.
• Legumes & dals like moth beans, green gram, Bengal
gram dal, etc.
• Roots & tubers such as beet, sweet potato, potato,
Colocasia, etc.
• Fruits like banana, mango, sapota (Chikoo), grapes
• Sugar, jaggery & honey. ( Honey has Low Glycemic
Index)
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Animal sources of dietary
carbohydrates
• Milk & milk products
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Functions of carbohydrates
in the body
• 1) Supply of energy –
• Carbohydrates undergo oxidation in living
cells of the body to release energy
• The energy thus released is supplied to the
cells of the body for carrying out the various
life processes
Carbohydrate Food
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Carbohydrate Deficiency –Tired
Fatigue
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Functions of carbohydrates
in the body
• 2) Protein sparing action –
• When carbohydrates are taken in large
amounts to meet the energy requirements of
the body, proteins are spared for their main
function, i.e. body building.
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Functions of carbohydrates
in the body
• 3) Regulation of fat metabolism -
Carbohydrates play an important role in
proper utilization of fat in the body.
• 4) Role in movement of bowels - Cellulose, a
kind of carbohydrate, is of great help in the
movement of bowels, as it provides roughage
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2) Proteins
• Proteins are organic compounds containing
carbon ( C ), hydrogen (H), oxygen (O) &
nitrogen (N)
• Some proteins contain sulphur (S) &
phosphorus (P) also -
• Some specialized proteins contain elements
like iodine & iron.
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Functions of proteins
• 1) Growth & maintenance
• Proteins, being the chief constituent of body
tissues, are required for building new tissues
in the body & for the replacement of worn
out tissues
• Protein requirement increases during growth,
pregnancy, lactation & convalescent period
Protein Deficiency – Weak Muscle
Power
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Functions of proteins
• 2) Regulation of chemical reactions in the
body
• i) The chemical reactions that take place in the
body are regulated by enzymes which are
nothing but proteins.
• ii) Hormones which regulate the growth &
development of the body are mostly protein
compounds
Protein Functions
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Functions of proteins
• 3) Protection
• Antibodies which protect the body from
infections are also proteins.
• 4) Source of energy
• One gram of protein gives about 4 calories of
energy. However, the body uses it as the last
sources of energy when carbohydrates & fats
are not available.
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1) Plant sources of
dietary proteins
• 1) Plant sources of dietary proteins
• Legumes & pulses like Bengal gram, lentil,
rajmah, soya bean, Bengal gram dal, green
gram dal & red gram dal
• Nuts & oil seeds such as groundnut, walnut,
cashew nut, sesame (til), almond, etc.
Protein Deficiency
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2) Animal sources of
dietary proteins
• Flesh food such as meat, fish, & poultry
• Eggs
• Milk & milk products (except butter & ghee).
Nutrient Deficiency
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3) Fats
• Fats are organic compounds containing carbon
(C), hydrogen (H), & oxygen (O).
• As compared to carbohydrates, fats contain
more hydrogen (H) & less oxygen (O).
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Plant sources of dietary fats
• Groundnut, coconut, sunflower seeds, cotton
seeds, mustard seeds
•
• Vanaspati ghee & margarine.
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Animal sources of dietary fats
• Whole milk & milk product like cream, butter,
ghee
• Egg, especially the egg yolk
• Animal fats like lard, margarine
• Fish & fish live oil
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Functions of fats
• 1) Source of energy - Fats are a rich source of
energy. 1 gram of fat provides about 9
kilocalories of energy.
• 2) Source of essential fatty acids - There are
some fatty acids, which are very essential for
the good health of the human body. Dietary
fats provide these essential fatty acids
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Functions of fats
• 3) Carrier of fat soluble vitamins - Fats are
carriers of fat soluble vitamins like vitamins A,
D, E & K.
• 4) Insulation - Fat stored in the form of layers
underneath the skin acts as insulator.
Insulation helps in maintaining the body
temperature.
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Functions of fats
• 5) Padding –
• Organs like liver & kidney are covered &
protected by a thin layer of fat which serves as
padding
• The padding protects these organs from
shocks & physical injuries.
Functions of fats
• 6) Palatability & satiety value –
• Fats improve the palatability of food
• They also increase the satiety value of food
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What is Margarine ?
• Margarine is a substitute for butter
• Margarine is prepared from vegetable &
animal fats by emulsifying them with water
• Skimmed milk powder, salt, vitamins &
coloring & flavoring matter are also added to
the emulsified fat to obtain margarine
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Disadvantages of taking fats
• Excessive intake of fat causes atheriosclerosis in
which the arteries are partially or completely blocked
resulting in reduced circulation of blood.
• Blockage of artery supplying blood to the heart leads
to coronary heart diseases.
•
• Excessive intake of fats causes obesity, which in turn
causes hypertension, liver disorder, renal disorder,
etc.
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4) Vitamins
• 1) Vitamins are vital organic substances, which
are essential for growth, development &
maintenance of the body.
•
• 2) Based on their solubility in fat or water,
vitamins have been classified into 2 groups,
viz. fat soluble vitamins & water - soluble
vitamins
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4) Vitamins
• i) Fat - soluble vitamins –
• Vitamins such as A, D, E & K, which are
soluble in fat, are called fat - soluble vitamins
• Fat - soluble vitamins are stored in the body.
4) Vitamins
• ii) Water soluble vitamins –
• Vitamins of B - complex group & vitamin C,
which are soluble in water, are called water -
soluble vitamins
• Water - soluble vitamins are not stored in the
body.
8/3/2016 Prof.Dr.R.R.Deshpande 99
8/3/2016 Prof.Dr.R.R.Deshpande 100
1) Retinol (Vitamin A)
• Retinol is vitamin A
• It is a fat - soluble vitamin occurring in both
plant & animal foodstuffs
Sources of Vitamin A
8/3/2016 Prof.Dr.R.R.Deshpande 101
8/3/2016 Prof.Dr.R.R.Deshpande 102
Functions of vitamin A
• 1) Retinol maintains the normal vision.
• 2) Retinol prevents night - blindness &
inflammation of the eyes.
• 3) Retinol is necessary for the growth of
skeleton & tissues.
• 4) Retinol keeps the skin & lining membrane
of the eyes, respiratory tract & intestinal tract,
healthy & moist
Vitamin A deficiency
8/3/2016 Prof.Dr.R.R.Deshpande 103
8/3/2016 Prof.Dr.R.R.Deshpande 104
Plant sources of vitamin A
• Orange or yellow - colored fruits & vegetables
such as mango, papaya, orange, carrot &
pumpkin & tomato
•
• Green leafy vegetables like spinach, coriander
leaves, colocasia leaves.
8/3/2016 Prof.Dr.R.R.Deshpande 105
Animal sources of vitamin A
• Fish & liver
• Milk & milk products
• Eggs
• Butter & ghee
8/3/2016 Prof.Dr.R.R.Deshpande 106
2) Vitamin D
• Natural sources of vitamin D
• Plant foods are not a rich source of vitamin D.
• The cheapest & easiest way of obtaining
vitamin D is exposure of the body to the
morning sun
• Besides this, it is also found in egg, liver, fish
liver oils, butter etc.
8/3/2016 Prof.Dr.R.R.Deshpande 107
Functions of vitamin D
• 1) Vitamin D is necessary for the growth &
development of bones
• 2) Vitamin D plays a vital role in absorption &
utilization of calcium & phosphorus which
make the bones strong & hard.
8/3/2016 Prof.Dr.R.R.Deshpande 108
Diseases caused due to
the deficiency of vitamin D
• 1) Softening of bones
• 2) Rickets
• 3) Dental decay
• 4) Imperfect bone formation.
Sources of Vitamin D3
8/3/2016 Prof.Dr.R.R.Deshpande 109
Rickets 10 Features
8/3/2016 Prof.Dr.R.R.Deshpande 110
Vitamin D deficiency –
causes & Symptoms
8/3/2016 Prof.Dr.R.R.Deshpande 111
8/3/2016 Prof.Dr.R.R.Deshpande 112
3) Vitamin E
• Sources of vitamin E
• Plant sources
• Vegetable oils such as safflower oil, groundnut oil,
etc.
• Whole grain cereals. Legumes & pulses.
• Nuts & oil seeds. Dark green leafy vegetables.
• Animal sources
• Liver, Egg yolk , Butter.
Sources of Vitamin E
8/3/2016 Prof.Dr.R.R.Deshpande 113
8/3/2016 Prof.Dr.R.R.Deshpande 114
Functions of vitamin E
• 1) Vitamin E acts as an antioxidant. Therefore,
it prevents the oxidation of fatty acids,
vitamins A & C in the food & in the body.
• 2) Vitamin E is necessary for normal
reproduction as it prevents sterility.
8/3/2016 Prof.Dr.R.R.Deshpande 115
4) Vitamin K
• Sources of vitamin K
• Plant sources
• Green leafy vegetables like fenugreek,
Colocasia, cabbage & spinach Cauliflower
Tomato.
• Animal sources
• Milk, Egg yolk , Liver, Brain
Sources of Vitamin K
8/3/2016 Prof.Dr.R.R.Deshpande 116
8/3/2016 Prof.Dr.R.R.Deshpande 117
Functions vitamin K
• 1) Vitamin K plays an important role in blood
clotting by forming prothrombin, which is one
of the necessary factors for blood clotting
• 2) Vitamin K is necessary for the normal
functioning of the liver.
8/3/2016 Prof.Dr.R.R.Deshpande 118
Fat - soluble vitamins &
their deficiency effects
8/3/2016 Prof.Dr.R.R.Deshpande 119
Vitamin B - complex
• Vitamins of B - complex group include a
number of water soluble vitamins like
• B1 (Thiamine)
• B2 (Riboflavin)
• B3 (Niacin)
• B6 (Pyridoxine)
• B12 (Cyanocobalamin) &
• folic acid.
8/3/2016 Prof.Dr.R.R.Deshpande 120
Thiamine
• Source of Thiamine (B1)
• Plant sources
• Whole grain cereals Legumes & pulses
• Nuts & oil seeds ,Dry yeast
• Animal sources
• Meat , Milk & milk products , Egg yolk.
Sources of Vitamin B1
8/3/2016 Prof.Dr.R.R.Deshpande 121
8/3/2016 Prof.Dr.R.R.Deshpande 122
Functions of thiamine
• 1) Thiamine plays an important role in
catalyzing the oxidation of glucose to produce
energy
• 2) Thiamine is essential for the proper growth
of the body.
Beriberi
8/3/2016 Prof.Dr.R.R.Deshpande 123
Wet Beriberi
8/3/2016 Prof.Dr.R.R.Deshpande 124
8/3/2016 Prof.Dr.R.R.Deshpande 125
Riboflavin (B2)
• Co - enzyme
• 1) Coenzyme is a substance which is needed
by enzymes to perform their functions
effectively
• 2) Riboflavin is a coenzyme which plays an
important role in carbohydrate, protein & fat
metabolism
8/3/2016 Prof.Dr.R.R.Deshpande 126
3) Niacin ( B 3)
• 1) Sources of Niacin
• Plant sources
• Cereals, legumes & pulses. Nuts & oil seeds.
• Green leafy vegetables.
• Animal sources
• Meat, fish & poultry. Milk & milk products.
8/3/2016 Prof.Dr.R.R.Deshpande 127
Functions of Niacin ( B 3)
• 1) Niacin acts as a coenzyme which helps in
releasing energy from consumed food
• 2) Niacin plays an important role in
carbohydrate, protein & fat metabolism
8/3/2016 Prof.Dr.R.R.Deshpande 128
4) Folic acid
• Sources of folic acid
• Plant sources - Fresh green leafy vegetables
Legumes
• Animal sources - Liver
8/3/2016 Prof.Dr.R.R.Deshpande 129
Functions (Uses) of folic acid
• 1) Folic acid plays an important role in
multiplication & maturation of cells
• 2) Folic acid is one of the essential factors in
the formation of hemoglobin.
8/3/2016 Prof.Dr.R.R.Deshpande 130
Cyanocobalmin
• Sources of vitamin B12
• Meat, liver , Milk & milk products.
• (Note - Vitamin B12 is not available in plants.)
8/3/2016 Prof.Dr.R.R.Deshpande 131
Functions of vitamin B12
• 1) Vitamin B12 is essential for maturation of
cells
• 2) Vitamin B12 is necessary for the proper
functioning of the nervous system.
• 3) Vitamin B12 plays an important role in the
formation of red blood corpuscles.
8/3/2016 Prof.Dr.R.R.Deshpande 132
Deficiency - effects of
vitamin B - Complex
• Retarded growth
• Nervous disorder
• Anaemia
• Beriberi
• Pellagra
8/3/2016 Prof.Dr.R.R.Deshpande 133
6) Vitamin C
• Plant sources of vitamin C (Ascorbic acid)
• Fresh fruits like Amla, Organge, guava, lemon
& lime.
• Fresh vegetables like ripe Tomato, capsicum,
cabbage etc.
• (Note - Animal foods contain little or no
vitamin C).
Sources of Vitamin C
8/3/2016 Prof.Dr.R.R.Deshpande 134
8/3/2016 Prof.Dr.R.R.Deshpande 135
Functions of vitamin C
(Ascorbic acid)
• 1) Vitamin C plays an important role in healing
of cuts & wounds. It is necessary for the
formation of collagen (a kind of protein)
which acts as cementing material in healing of
cuts & wounds.
• 2) Vitamin C increases the absorption of
dietary iron & calcium in the body.
8/3/2016 Prof.Dr.R.R.Deshpande 136
Functions of vitamin C
(Ascorbic acid)
• 3) Vitamin C prevents scurvy which causes the
decay of gums & teeth.
• 4) Vitamin C helps in releasing certain
hormones which help the body to deal with
physical & mental tensions
Scurvy
8/3/2016 Prof.Dr.R.R.Deshpande 137
Scurvy Gums
8/3/2016 Prof.Dr.R.R.Deshpande 138
Scurvy Skin bleeding
8/3/2016 Prof.Dr.R.R.Deshpande 139
8/3/2016 Prof.Dr.R.R.Deshpande 140
General characters of
vitamin B & C
• Both vitamin B & C are soluble in water
• Both vitamin B & C are not stored in the body
• Both vitamin B & C are destroyed by cooking
8/3/2016 Prof.Dr.R.R.Deshpande 141
Ascorbic acid (Vitamin C)
is the most unstable vitamin
• 1) Ascorbic acid is easily destroyed by heat,
ageing, drying, storing & oxidation
•
• 2) Ascorbic acid is highly soluble in water.
Therefore, when chopped vegetables are
washed or when cooking water is discarded,
the ascorbic acid is lost.
8/3/2016 Prof.Dr.R.R.Deshpande 142
Food Stuff & Vitamins
8/3/2016 Prof.Dr.R.R.Deshpande 143
Food Stuff & Vitamins
8/3/2016 Prof.Dr.R.R.Deshpande 144
Food Stuff & Vitamins
8/3/2016 Prof.Dr.R.R.Deshpande 145
Food Stuff & Vitamins
8/3/2016 Prof.Dr.R.R.Deshpande 146
Food Stuff & Vitamins
Prof.Dr.R.R.Deshpande
• Sharing of Knowledge
• FOR
• Propagating Ayurved
8/3/2016 147Prof.Dr.R.R.Deshpande

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Basic components of food & Metabolism part 1

  • 1. Basic Components of Food & Metabolism • Presented By – • Prof.Dr.R.R.Deshpande (M.D in Ayurvdic Medicine & M.D. in Ayurvedic Physiology) • www.ayurvedicfriend.com • Mobile – 922 68 10 630 • professordeshpande@gmail. com 8/3/2016 Prof.Dr.R.R.Deshpande 1
  • 2. 8/3/2016 Prof.Dr.R.R.Deshpande 2 8/3/2016 Prof.Dr.R.R.Deshpande 2 Sharir Kriya -- Paper I – Part B –Point f • Presented By – • Prof.Dr.R.R.Deshpande (M.D in Ayurvdic Medicine & M.D. in Ayurvedic Physiology) • www.ayurvedicfriend.com • Mobile – 922 68 10 630 • mailme.drrrdeshpande@rediffmail.com
  • 3. Sharir Kriya Paper 1-Part B –Set 2 • Presented By – • Dr.R.R.Deshpande • Prof & HOD • CARC ,Pune 44 8/3/2016 Prof.Dr.R.R.Deshpande 3
  • 4. 8/3/2016 Prof.Dr.R.R.Deshpande 4 8/3/2016 Prof.Dr.R.R.Deshpande 4 Sharir Kriya Hand Book – 1st to last year BAMS • Best for Fast Revision • Paper 1,Paper 2 • Practicals • Instruments • Histology • IMP Schlok • All basics of Dodha,Dhatu & Mala
  • 5. 8/3/2016 Prof.Dr.R.R.Deshpande 5 8/3/2016 Prof.Dr.R.R.Deshpande 5 Sharikriya Paper Practical Book • As per Very New Syllabus formed By CCIM IN 2012 • Ayurvedic Practicals like Prakruti,sara,Agni • Modern Haematological Practicals • CNS & CVS Examination
  • 6. 8/3/2016 Prof.Dr.R.R.Deshpande 6 8/3/2016 Prof.Dr.R.R.Deshpande 6 Clinical Examination • Systemic Examination of 8 systems • Ayurvedic Srotas Examination • Clinical significance of Lab Tests & Radiology,USG,2D Echo
  • 7. 8/3/2016 Prof.Dr.R.R.Deshpande 7 8/3/2016 Prof.Dr.R.R.Deshpande 7 Sharir Kriya Paper 1 • Book in English • Total CCIM Syllabus covered • Chaukhamba Sanskrit Pratisthan Publication • Popular Nationwide & In Germany also • Dosha & Prakruti
  • 8. 8/3/2016 Prof.Dr.R.R.Deshpande 8 8/3/2016 Prof.Dr.R.R.Deshpande 8 Sharir Kriya Paper 2 • Book in English • Total CCIM Syllabus covered • Chaukhamba Sanskrit Pratisthan Publication • Popular Nationwide & In Germany also • Dhatu,Mala
  • 9. 8/3/2016 Prof.Dr.R.R.Deshpande 9 Prof.Dr.Deshpande’s Popular Links on Internet • Just Start Internet on Desk top or Lap top or on your mobile . Copy Following Link & Paste as Web address –URL • http://www.youtube.com/user/deshpande19 59 • http://www.slideshare.net/rajendra9a/ • http://www.mixcloud.com/jamdadey/ 8/3/2016 Prof.Dr.R.R.Deshpande 9
  • 10. 8/3/2016 Prof.Dr.R.R.Deshpande 10 Prof.Dr.Deshpande’s Popular Links on Internet • Just Start Internet on Desk top or Lap top or on your mobile . Copy Following Link & Paste as Web address –URL • http://professordeshpande.blogspot.in • http://professordrdeshpande.blogspot.in/ • http://www.mixcloud.com/rajendra- deshpande • https://soundcloud.com/professor-deshpande 8/3/2016 Prof.Dr.R.R.Deshpande 10
  • 11. 8/3/2016 Prof.Dr.R.R.Deshpande 11 Acid Base Balance • Acid Base balance is very important for the homeostasis. • An acid is the proton donor means which liberates hydrogen ions. • A base is the proton acceptor means which accepts hydrogen ions. • In the human body the concentration of free hydrogen ion is maintained same at the level of 7. 4 pH.
  • 12. Acid Base Balance 8/3/2016 Prof.Dr.R.R.Deshpande 12
  • 13. 8/3/2016 Prof.Dr.R.R.Deshpande 13 What is pH? • pH means hydrogen ion concentration. • Increased in hydrogen ion concentration decreases the pH (Less than 7), which is called as acidosis. • Reduction in hydrogen ion conc. Increases the pH (Greater than 7) which is called as alkalosis. • ECF, in healthy person has a pH range from 7. 38 to 7. 42.
  • 14. Acid Base Balance 8/3/2016 Prof.Dr.R.R.Deshpande 14
  • 15. 8/3/2016 Prof.Dr.R.R.Deshpande 15 Measurement of Acid Base status • Acid base status of ECF is determined by Henderson - Hasselbalch equation • pH = pK + log (HCO3 / CO2) • pH of plasma is more important this is determined by pH meter. • pH of arterial blood is an indirect measurement of H+ ion concentration & it indicates the balance of CO2 & HCO - 3.
  • 16. 8/3/2016 Prof.Dr.R.R.Deshpande 16 Regulation of Acid base balance • Human body has a constant fear of acidosis. • • 2 types of acids are constantly produced in the body. • Volatile acids are derived from CO2 (which is produced during metabolism of carbohydrates & fats) • Non - volatile acids - are produced during the metabolism of proteins.
  • 17. 8/3/2016 Prof.Dr.R.R.Deshpande 17 Mechanisms to regulate Acid Base balance • Acid base buffer system (which binds free hydrogen ions) • Respiratory mechanism (which eliminates CO2) • Renal mechanism (which excretes H+ & preserve HCO3 -).
  • 18. 8/3/2016 Prof.Dr.R.R.Deshpande 18 Acid - Base buffer system • This is the fastest mechanism & resettled the pH within seconds. • 3 types of buffer system are ----
  • 19. 8/3/2016 Prof.Dr.R.R.Deshpande 19 I) Bi - carbonate buffer system • This is present in plasma of ECF, consist of carbonic acid (H2CO3) & a salt sodium bi - carbonate (NaHCO3). • This system prevents the fall of pH in a fluid to which a strong acid like HCl is added & also prevents increase in pH when strong base like NaOH is added
  • 20. 8/3/2016 Prof.Dr.R.R.Deshpande 20 I) Bi - carbonate buffer system • This buffer system is not powerful, but it plays an important role in maintaining the pH of body fluids than the other buffer systems. • This system works effectively because of 2 regulatory mechanisms (conc. of HCO3- is regulated by kidneys & conc. of CO2 is regulated by respiratory system.)
  • 21. 8/3/2016 Prof.Dr.R.R.Deshpande 21 II) Phosphate buffer system • This system has a weak acid that is sodium di hydrogen phosphate (NaH2PO4) a base Di - sodium hydrogen phosphate(Na2HPO4). • • This system is useful in ICF, in RBC. This system is more powerful than bicarbonate buffer system.
  • 22. 8/3/2016 Prof.Dr.R.R.Deshpande 22 III) Protein buffer system • Is present in plasma as well as in RBCs. • Haemoglobin is the most effective protein buffer in the blood, Hb prevents fall in pH when more & more CO2 enters in to the capillaries
  • 23. 8/3/2016 Prof.Dr.R.R.Deshpande 23 2) Acid base balance By respiratory system • Lungs maintain acid base balance by removing CO2. • When metabolic activity increase more CO2 is produced in the tissue & increase in H+ ion concentration (CO2 + H2O - H2CO3 - H+ & HCO3 ions) due to increase in H+ concentration hyper ventilation takes place & excess of CO2 is removed from the body.
  • 24. 8/3/2016 Prof.Dr.R.R.Deshpande 24 3) Acid base balance By Renal system • During urine formation process ---- • There is secretion of H+ & • Retention of HCO3–
  • 25. 8/3/2016 Prof.Dr.R.R.Deshpande 25 Applied part of Acid Base balance • 1) Acidosis – • This is increase in H+ ion concentration & pH becomes less than 6 • This occurs due to increase in Pco2 in arterial blood & decrease in HCO3– .
  • 26. Applied part of Acid Base balance • 2) Alkolosis – • This is decrease in H+ conc. & • Increase in pH that is greater than 7. • Acid base disturbances - They are mainly 2 types 8/3/2016 Prof.Dr.R.R.Deshpande 26
  • 27. 8/3/2016 Prof.Dr.R.R.Deshpande 27 1. Respiratory Acidosis • PCO2 in arterial blood = 40 mmHg. Acidosis takes place when it is above 60mmHg. • Common causes of acidosis are broncho spasm, emphysema, pneumonia, cerebral trauma, paralysis of respiratory muscle, hypoventilation or decrease ventilation is the main pathology in acidosis.
  • 28. 8/3/2016 Prof.Dr.R.R.Deshpande 28 2. Respiratory Alkalosis • This occurs when PCO2 is less than 20 mmHg. • Hyperventilation is the main pathology for loss of excess CO2. • The main causes of hyper ventilation in respiratory alkalosis are high altitude, severe anaemia, cerebral disturbances, pulmonary oedema, psychological trauma.
  • 29. 8/3/2016 Prof.Dr.R.R.Deshpande 29 3. Metabolic Acidosis • This is due to excess accumulation of like lactic acid, ketoacidosis & uric acid. • Main causes are lactic acidosis in circulatory shock, ketoacidosis in DM, Uric acidosis in renal failure
  • 31. 8/3/2016 Prof.Dr.R.R.Deshpande 31 4. Metabolic Alkalosis • This is cause by loss of excess H+ ion & increase HCO3– conc. • The common causes are diuretic drugs, vomiting, Cushing’s syndrome.
  • 33. 8/3/2016 Prof.Dr.R.R.Deshpande 33 Water & Electrolyte Balance • Regulation of Water balance • Water content of the blood has always a communication with interstitial fluid. • This helps in the water regulation, skin also regulates water quantity & electrolyte balance by excretion of water & salts through sweat.
  • 34. 8/3/2016 Prof.Dr.R.R.Deshpande 34 Fluid compartments in the Human Body • Body fluid consist of water & dissolved solutes that is electrolyte. • This fluid has in a range of 55 - 60% of total body weight.
  • 35. Fluid compartments in the Human Body • For the healthy condition homeostasis of body fluid is essential. • 2/3rd of the body fluid is intracellular (ICF) • 1/3rd is extracellular (ECF). • 80% of ECF is interstitial fluid & 20% is blood plasma 8/3/2016 Prof.Dr.R.R.Deshpande 35
  • 36. 8/3/2016 Prof.Dr.R.R.Deshpande 36 Fluid compartments in the Human Body • Fluid moves from one compartment to another but keeping the same proportion as mentioned above. • As water is main part of body fluid, fluid balance means water balance. • Electrolytes (Inorganic compounds which dissociate in to ions) are main solutes in body fluid so, fluid balance means also electrolyte balance.
  • 37. 8/3/2016 Prof.Dr.R.R.Deshpande 37 Body water • Infants have water content, up to 75% of body weight. • This amount decreases with age as adipose tissue contains no water, fat people have less amount of water than lean people. • In male water is 60% of body weight & in female it is 55%.
  • 38. 8/3/2016 Prof.Dr.R.R.Deshpande 38 Water gain & Water loss • Water gain • 1600 ml through ingested liquids (beverages) • • 700 ml through ingested food • 200 ml through metabolic water. • Total gain is 2500ml.
  • 39. Water gain & Water loss • Water loss • 1500 ml of water loss takes place through kidneys • 600ml through skin • 300 ml through lungs • 200 ml through digestive system • Total water loss = 2500ml. • Usually water loss is same as water gain. This is homeostasis 8/3/2016 Prof.Dr.R.R.Deshpande 39
  • 40. Water Gain & Water Loss 8/3/2016 Prof.Dr.R.R.Deshpande 40
  • 41. 8/3/2016 Prof.Dr.R.R.Deshpande 41 Regulation of fluid gain • This is done mainly through drinking more or less fluid. Regulation takes place as follows – • Dehydration takes place when water loss is more than water gain (In the condition like watery diarrhoea, vomiting, fever, diuretics) Dehydration stimulates thirst.
  • 42. 8/3/2016 Prof.Dr.R.R.Deshpande 42 Regulation of fluid gain • When production of saliva decreases it causes dryness of the mouth. • When blood volume decreases, hypotension develops, which stimulates rennin - angiotensin mechanism • Angiotensin 2 too stimulates thirst centre. • Naturally person drinks more water & normal fluid volume is restored
  • 43. 8/3/2016 Prof.Dr.R.R.Deshpande 43 Regulation of fluid loss • This is controlled by anti - diuretic hormone (ADH) Aldosteron & atrial natriuretic peptide (ANP) • Water over load increases blood pressure & the rate of glomerular filtration increase so more water is loss in the urine.
  • 45. 8/3/2016 Prof.Dr.R.R.Deshpande 45 Caution • 1) If repeated enemas are given in young children, can increase the risk of fluid & electrolyte imbalances. • 2) Why isotonic solution is given? - usually tap water is hypotonic & commercially prepaid solutions are hypertonic. Both this type of solutions can cause rapid fluid & electrolyte shift.
  • 46. 8/3/2016 Prof.Dr.R.R.Deshpande 46 About Electrolytes • Definition – • Inorganic substance which dissociate in to ion, in solutions is called an electrolyte • Because now this solution can conduct an electric current
  • 47. 8/3/2016 Prof.Dr.R.R.Deshpande 47 About Electrolytes • Electrolytes dissociates in to cations (Positively charged ions) & anions (negatively charge ions) • Acids, bases & salts are electrolytes, unites which express the total number of particles in a given volume of solution are expressed as milli osmoles per litre • Electrolytes have a greater effect on osmosis
  • 48. 8/3/2016 Prof.Dr.R.R.Deshpande 48 Comparison of Electrolytes in different fluid compartments • In ECF - Major cations is Na+ & major anions Cl- & HCO3- • In ICF - Major cat ions is K+ & major anions are proteins & phosphates (ATP).
  • 49. 8/3/2016 Prof.Dr.R.R.Deshpande 49 About different Ions • 1. Sodium ions are more in extracellular fluid. • They help in impulse transmission, muscle contraction & fluid & electrolyte balance. • Sodium level is controlled by Aldosteron
  • 50. 8/3/2016 Prof.Dr.R.R.Deshpande 50 About different Ions • 2. Potassium ions are more in intracellular fluid. • They are responsible for fluid volume, impulse conduction, muscle contraction & pH regulation. • Potassium level is controlled by Aldosteron.
  • 51. 8/3/2016 Prof.Dr.R.R.Deshpande 51 About different Ions • 3. Calcium – • Ca++ is extracellular cation. • This is responsible for blood clotting, neurotransmitter release, contraction of muscle. • Level is maintained by 2 hormones as parathyroid hormone & calcitonin
  • 52. 8/3/2016 Prof.Dr.R.R.Deshpande 52 About different Ions • 4. Magnesium ions – • This is intracellular cations.( Positive Charge) • They are co - factors in several enzyme systems.
  • 53. 8/3/2016 Prof.Dr.R.R.Deshpande 53 About different Ions • 5. Chlorides are major extracellular anions they are helpful for regulating osmotic pressure & forming HCl • Level is indirectly controlled by Aldosteron
  • 54. 8/3/2016 Prof.Dr.R.R.Deshpande 54 About different Ions • 6. Bi - carbonate ions – • Present in extracellular fluid • They help as important buffer in plasma.
  • 55. About different Ions • 7. Phosphate ions – • They are intracellular anions & there salts are structural components of bones & teeth • They are useful for synthesis of nucleic acids & ATP. Level is controlled by PTH & CT 8/3/2016 Prof.Dr.R.R.Deshpande 55
  • 56. 8/3/2016 Prof.Dr.R.R.Deshpande 56 Imbalance in Electrolytes • 1) Sodium imbalance • Hyponatremia occurs in the conditions like vomiting, diarrhoea, during diuretic therapy, burn, excessive sweating. • Clinical features are muscle weakness dizziness, headache, hypotension, tachycardia, shock & some times confusion, stupor & coma.
  • 57. Sodium Imbalance • Hypernatremia occurs with water loss or excessive sodium by eating salted snaks,pickles,Papad etc • Clinical features are excessive thirst , fatigue hypertension, restlessness & some times coma. 8/3/2016 Prof.Dr.R.R.Deshpande 57
  • 58. 8/3/2016 Prof.Dr.R.R.Deshpande 58 2) Chloride imbalance • Hypochloremia – • Caused by vomiting, diarrhoea, excess dose of lasix • Clinical features are muscle spasm (calf pain) depressed respiration & some times coma.
  • 59. 8/3/2016 Prof.Dr.R.R.Deshpande 59 3) Potassium imbalance • Hypokalemia occurs in vomiting, diarrhoea, diuretics & less sodium intake • Clinical features are cramps, fatigue, flaccid paralysis, nausea, vomiting, mental confusion, shallow respiration, ECG changes (prolonged QT interval & flattening of T wave) • To prevent hypokalemia recently potassium sparing diuretics are used like Tab. Amiphru Or Tab. Lacilactone
  • 60. 8/3/2016 Prof.Dr.R.R.Deshpande 60 3) Potassium imbalance • Hyperkalemia – • Features are irritability, abdominal cramps, diarrhoea, weakness of lower limbs, burning or prickling sensation • In extreme case due to fibrillation of the heart patient can die.
  • 61. 8/3/2016 Prof.Dr.R.R.Deshpande 61 4) Calcium imbalance • Hypocalcemia can occur -- • Due to reduced calcium intake, hypoparathyroidism, increased calcium loss in old age • Clinical features are Tetany, muscle cramp, convulsions, tingling numbness, bone fractures, osteoporosis.
  • 62. 4) Calcium imbalance • Hypercalcemia – • Due to over dose of calcium tablets • Features are lethargy, nausea, itching, bone pain, depression. 8/3/2016 Prof.Dr.R.R.Deshpande 62
  • 63. 8/3/2016 Prof.Dr.R.R.Deshpande 63 5) Phosphate imbalance • Hypophosphatemia – • Occurs due to increased urinary loss, intestinal obstruction • Features are chest & muscle pain, tingling numbness, susceptibility to infection.
  • 64. 5) Phosphate imbalance • Hyperphosphatemia – • Occrs due to renal failure too excrete excess phosphate • Features are nausea, tetany, hyperactive reflexes 8/3/2016 Prof.Dr.R.R.Deshpande 64
  • 65. 8/3/2016 Prof.Dr.R.R.Deshpande 65 6) Magnesium imbalance • Hypomagnesemia – • Occurs due to diarrhoea, alcoholism, malnutrition, DM, diuretic drugs, excessive lactation • Features are weakness, tetany, nausea, cardiac arrhythmia.
  • 66. 6) Magnesium imbalance • Hypermagnesemia – • Occurs due to renal failure or increased intake of magnesium containing antacids, acute diabetic ketoacidosis. • Features are nausea, hypotension, altered mental functioning. 8/3/2016 Prof.Dr.R.R.Deshpande 66
  • 67. 8/3/2016 Prof.Dr.R.R.Deshpande 67 Basic components of food • Nutrients in food • 1) Nutrients • The chemical components of food which when consumed, nourish the body & regulate the various functions of the body are called nutrients.
  • 68. 8/3/2016 Prof.Dr.R.R.Deshpande 68 2) Nutrients present in the food (Proximal principles of food) • 1) Carbohydrates • 2) Proteins • 3) Fats • 4) Vitamins • 5) Minerals • 6) Water
  • 69. Sources of Proteins, Carbohydrates & Fats 8/3/2016 Prof.Dr.R.R.Deshpande 69
  • 70. 8/3/2016 Prof.Dr.R.R.Deshpande 70 1) Carbohydrates • Carbohydrates are organic compounds containing carbon (C), hydrogen (H) & oxygen (O). • Carbohydrates are the most abundant organic compounds that are found in the living world. • Carbohydrates are synthesized by green plants by a process called photosynthesis. • One gram of carbohydrate provides approximately 4 calories of energy.
  • 71. 8/3/2016 Prof.Dr.R.R.Deshpande 71 Plant sources of dietary carbohydrates • Cereals & millets like wheat, rice, maize, jowar, bajra, ragi etc. • Legumes & dals like moth beans, green gram, Bengal gram dal, etc. • Roots & tubers such as beet, sweet potato, potato, Colocasia, etc. • Fruits like banana, mango, sapota (Chikoo), grapes • Sugar, jaggery & honey. ( Honey has Low Glycemic Index)
  • 72. 8/3/2016 Prof.Dr.R.R.Deshpande 72 Animal sources of dietary carbohydrates • Milk & milk products
  • 73. 8/3/2016 Prof.Dr.R.R.Deshpande 73 Functions of carbohydrates in the body • 1) Supply of energy – • Carbohydrates undergo oxidation in living cells of the body to release energy • The energy thus released is supplied to the cells of the body for carrying out the various life processes
  • 76. 8/3/2016 Prof.Dr.R.R.Deshpande 76 Functions of carbohydrates in the body • 2) Protein sparing action – • When carbohydrates are taken in large amounts to meet the energy requirements of the body, proteins are spared for their main function, i.e. body building.
  • 77. 8/3/2016 Prof.Dr.R.R.Deshpande 77 Functions of carbohydrates in the body • 3) Regulation of fat metabolism - Carbohydrates play an important role in proper utilization of fat in the body. • 4) Role in movement of bowels - Cellulose, a kind of carbohydrate, is of great help in the movement of bowels, as it provides roughage
  • 78. 8/3/2016 Prof.Dr.R.R.Deshpande 78 2) Proteins • Proteins are organic compounds containing carbon ( C ), hydrogen (H), oxygen (O) & nitrogen (N) • Some proteins contain sulphur (S) & phosphorus (P) also - • Some specialized proteins contain elements like iodine & iron.
  • 79. 8/3/2016 Prof.Dr.R.R.Deshpande 79 Functions of proteins • 1) Growth & maintenance • Proteins, being the chief constituent of body tissues, are required for building new tissues in the body & for the replacement of worn out tissues • Protein requirement increases during growth, pregnancy, lactation & convalescent period
  • 80. Protein Deficiency – Weak Muscle Power 8/3/2016 Prof.Dr.R.R.Deshpande 80
  • 81. 8/3/2016 Prof.Dr.R.R.Deshpande 81 Functions of proteins • 2) Regulation of chemical reactions in the body • i) The chemical reactions that take place in the body are regulated by enzymes which are nothing but proteins. • ii) Hormones which regulate the growth & development of the body are mostly protein compounds
  • 83. 8/3/2016 Prof.Dr.R.R.Deshpande 83 Functions of proteins • 3) Protection • Antibodies which protect the body from infections are also proteins. • 4) Source of energy • One gram of protein gives about 4 calories of energy. However, the body uses it as the last sources of energy when carbohydrates & fats are not available.
  • 84. 8/3/2016 Prof.Dr.R.R.Deshpande 84 1) Plant sources of dietary proteins • 1) Plant sources of dietary proteins • Legumes & pulses like Bengal gram, lentil, rajmah, soya bean, Bengal gram dal, green gram dal & red gram dal • Nuts & oil seeds such as groundnut, walnut, cashew nut, sesame (til), almond, etc.
  • 86. 8/3/2016 Prof.Dr.R.R.Deshpande 86 2) Animal sources of dietary proteins • Flesh food such as meat, fish, & poultry • Eggs • Milk & milk products (except butter & ghee).
  • 88. 8/3/2016 Prof.Dr.R.R.Deshpande 88 3) Fats • Fats are organic compounds containing carbon (C), hydrogen (H), & oxygen (O). • As compared to carbohydrates, fats contain more hydrogen (H) & less oxygen (O).
  • 89. 8/3/2016 Prof.Dr.R.R.Deshpande 89 Plant sources of dietary fats • Groundnut, coconut, sunflower seeds, cotton seeds, mustard seeds • • Vanaspati ghee & margarine.
  • 90. 8/3/2016 Prof.Dr.R.R.Deshpande 90 Animal sources of dietary fats • Whole milk & milk product like cream, butter, ghee • Egg, especially the egg yolk • Animal fats like lard, margarine • Fish & fish live oil
  • 91. 8/3/2016 Prof.Dr.R.R.Deshpande 91 Functions of fats • 1) Source of energy - Fats are a rich source of energy. 1 gram of fat provides about 9 kilocalories of energy. • 2) Source of essential fatty acids - There are some fatty acids, which are very essential for the good health of the human body. Dietary fats provide these essential fatty acids
  • 92. 8/3/2016 Prof.Dr.R.R.Deshpande 92 Functions of fats • 3) Carrier of fat soluble vitamins - Fats are carriers of fat soluble vitamins like vitamins A, D, E & K. • 4) Insulation - Fat stored in the form of layers underneath the skin acts as insulator. Insulation helps in maintaining the body temperature.
  • 93. 8/3/2016 Prof.Dr.R.R.Deshpande 93 Functions of fats • 5) Padding – • Organs like liver & kidney are covered & protected by a thin layer of fat which serves as padding • The padding protects these organs from shocks & physical injuries.
  • 94. Functions of fats • 6) Palatability & satiety value – • Fats improve the palatability of food • They also increase the satiety value of food 8/3/2016 Prof.Dr.R.R.Deshpande 94
  • 95. 8/3/2016 Prof.Dr.R.R.Deshpande 95 What is Margarine ? • Margarine is a substitute for butter • Margarine is prepared from vegetable & animal fats by emulsifying them with water • Skimmed milk powder, salt, vitamins & coloring & flavoring matter are also added to the emulsified fat to obtain margarine
  • 96. 8/3/2016 Prof.Dr.R.R.Deshpande 96 Disadvantages of taking fats • Excessive intake of fat causes atheriosclerosis in which the arteries are partially or completely blocked resulting in reduced circulation of blood. • Blockage of artery supplying blood to the heart leads to coronary heart diseases. • • Excessive intake of fats causes obesity, which in turn causes hypertension, liver disorder, renal disorder, etc.
  • 97. 8/3/2016 Prof.Dr.R.R.Deshpande 97 4) Vitamins • 1) Vitamins are vital organic substances, which are essential for growth, development & maintenance of the body. • • 2) Based on their solubility in fat or water, vitamins have been classified into 2 groups, viz. fat soluble vitamins & water - soluble vitamins
  • 98. 8/3/2016 Prof.Dr.R.R.Deshpande 98 4) Vitamins • i) Fat - soluble vitamins – • Vitamins such as A, D, E & K, which are soluble in fat, are called fat - soluble vitamins • Fat - soluble vitamins are stored in the body.
  • 99. 4) Vitamins • ii) Water soluble vitamins – • Vitamins of B - complex group & vitamin C, which are soluble in water, are called water - soluble vitamins • Water - soluble vitamins are not stored in the body. 8/3/2016 Prof.Dr.R.R.Deshpande 99
  • 100. 8/3/2016 Prof.Dr.R.R.Deshpande 100 1) Retinol (Vitamin A) • Retinol is vitamin A • It is a fat - soluble vitamin occurring in both plant & animal foodstuffs
  • 101. Sources of Vitamin A 8/3/2016 Prof.Dr.R.R.Deshpande 101
  • 102. 8/3/2016 Prof.Dr.R.R.Deshpande 102 Functions of vitamin A • 1) Retinol maintains the normal vision. • 2) Retinol prevents night - blindness & inflammation of the eyes. • 3) Retinol is necessary for the growth of skeleton & tissues. • 4) Retinol keeps the skin & lining membrane of the eyes, respiratory tract & intestinal tract, healthy & moist
  • 103. Vitamin A deficiency 8/3/2016 Prof.Dr.R.R.Deshpande 103
  • 104. 8/3/2016 Prof.Dr.R.R.Deshpande 104 Plant sources of vitamin A • Orange or yellow - colored fruits & vegetables such as mango, papaya, orange, carrot & pumpkin & tomato • • Green leafy vegetables like spinach, coriander leaves, colocasia leaves.
  • 105. 8/3/2016 Prof.Dr.R.R.Deshpande 105 Animal sources of vitamin A • Fish & liver • Milk & milk products • Eggs • Butter & ghee
  • 106. 8/3/2016 Prof.Dr.R.R.Deshpande 106 2) Vitamin D • Natural sources of vitamin D • Plant foods are not a rich source of vitamin D. • The cheapest & easiest way of obtaining vitamin D is exposure of the body to the morning sun • Besides this, it is also found in egg, liver, fish liver oils, butter etc.
  • 107. 8/3/2016 Prof.Dr.R.R.Deshpande 107 Functions of vitamin D • 1) Vitamin D is necessary for the growth & development of bones • 2) Vitamin D plays a vital role in absorption & utilization of calcium & phosphorus which make the bones strong & hard.
  • 108. 8/3/2016 Prof.Dr.R.R.Deshpande 108 Diseases caused due to the deficiency of vitamin D • 1) Softening of bones • 2) Rickets • 3) Dental decay • 4) Imperfect bone formation.
  • 109. Sources of Vitamin D3 8/3/2016 Prof.Dr.R.R.Deshpande 109
  • 110. Rickets 10 Features 8/3/2016 Prof.Dr.R.R.Deshpande 110
  • 111. Vitamin D deficiency – causes & Symptoms 8/3/2016 Prof.Dr.R.R.Deshpande 111
  • 112. 8/3/2016 Prof.Dr.R.R.Deshpande 112 3) Vitamin E • Sources of vitamin E • Plant sources • Vegetable oils such as safflower oil, groundnut oil, etc. • Whole grain cereals. Legumes & pulses. • Nuts & oil seeds. Dark green leafy vegetables. • Animal sources • Liver, Egg yolk , Butter.
  • 113. Sources of Vitamin E 8/3/2016 Prof.Dr.R.R.Deshpande 113
  • 114. 8/3/2016 Prof.Dr.R.R.Deshpande 114 Functions of vitamin E • 1) Vitamin E acts as an antioxidant. Therefore, it prevents the oxidation of fatty acids, vitamins A & C in the food & in the body. • 2) Vitamin E is necessary for normal reproduction as it prevents sterility.
  • 115. 8/3/2016 Prof.Dr.R.R.Deshpande 115 4) Vitamin K • Sources of vitamin K • Plant sources • Green leafy vegetables like fenugreek, Colocasia, cabbage & spinach Cauliflower Tomato. • Animal sources • Milk, Egg yolk , Liver, Brain
  • 116. Sources of Vitamin K 8/3/2016 Prof.Dr.R.R.Deshpande 116
  • 117. 8/3/2016 Prof.Dr.R.R.Deshpande 117 Functions vitamin K • 1) Vitamin K plays an important role in blood clotting by forming prothrombin, which is one of the necessary factors for blood clotting • 2) Vitamin K is necessary for the normal functioning of the liver.
  • 118. 8/3/2016 Prof.Dr.R.R.Deshpande 118 Fat - soluble vitamins & their deficiency effects
  • 119. 8/3/2016 Prof.Dr.R.R.Deshpande 119 Vitamin B - complex • Vitamins of B - complex group include a number of water soluble vitamins like • B1 (Thiamine) • B2 (Riboflavin) • B3 (Niacin) • B6 (Pyridoxine) • B12 (Cyanocobalamin) & • folic acid.
  • 120. 8/3/2016 Prof.Dr.R.R.Deshpande 120 Thiamine • Source of Thiamine (B1) • Plant sources • Whole grain cereals Legumes & pulses • Nuts & oil seeds ,Dry yeast • Animal sources • Meat , Milk & milk products , Egg yolk.
  • 121. Sources of Vitamin B1 8/3/2016 Prof.Dr.R.R.Deshpande 121
  • 122. 8/3/2016 Prof.Dr.R.R.Deshpande 122 Functions of thiamine • 1) Thiamine plays an important role in catalyzing the oxidation of glucose to produce energy • 2) Thiamine is essential for the proper growth of the body.
  • 125. 8/3/2016 Prof.Dr.R.R.Deshpande 125 Riboflavin (B2) • Co - enzyme • 1) Coenzyme is a substance which is needed by enzymes to perform their functions effectively • 2) Riboflavin is a coenzyme which plays an important role in carbohydrate, protein & fat metabolism
  • 126. 8/3/2016 Prof.Dr.R.R.Deshpande 126 3) Niacin ( B 3) • 1) Sources of Niacin • Plant sources • Cereals, legumes & pulses. Nuts & oil seeds. • Green leafy vegetables. • Animal sources • Meat, fish & poultry. Milk & milk products.
  • 127. 8/3/2016 Prof.Dr.R.R.Deshpande 127 Functions of Niacin ( B 3) • 1) Niacin acts as a coenzyme which helps in releasing energy from consumed food • 2) Niacin plays an important role in carbohydrate, protein & fat metabolism
  • 128. 8/3/2016 Prof.Dr.R.R.Deshpande 128 4) Folic acid • Sources of folic acid • Plant sources - Fresh green leafy vegetables Legumes • Animal sources - Liver
  • 129. 8/3/2016 Prof.Dr.R.R.Deshpande 129 Functions (Uses) of folic acid • 1) Folic acid plays an important role in multiplication & maturation of cells • 2) Folic acid is one of the essential factors in the formation of hemoglobin.
  • 130. 8/3/2016 Prof.Dr.R.R.Deshpande 130 Cyanocobalmin • Sources of vitamin B12 • Meat, liver , Milk & milk products. • (Note - Vitamin B12 is not available in plants.)
  • 131. 8/3/2016 Prof.Dr.R.R.Deshpande 131 Functions of vitamin B12 • 1) Vitamin B12 is essential for maturation of cells • 2) Vitamin B12 is necessary for the proper functioning of the nervous system. • 3) Vitamin B12 plays an important role in the formation of red blood corpuscles.
  • 132. 8/3/2016 Prof.Dr.R.R.Deshpande 132 Deficiency - effects of vitamin B - Complex • Retarded growth • Nervous disorder • Anaemia • Beriberi • Pellagra
  • 133. 8/3/2016 Prof.Dr.R.R.Deshpande 133 6) Vitamin C • Plant sources of vitamin C (Ascorbic acid) • Fresh fruits like Amla, Organge, guava, lemon & lime. • Fresh vegetables like ripe Tomato, capsicum, cabbage etc. • (Note - Animal foods contain little or no vitamin C).
  • 134. Sources of Vitamin C 8/3/2016 Prof.Dr.R.R.Deshpande 134
  • 135. 8/3/2016 Prof.Dr.R.R.Deshpande 135 Functions of vitamin C (Ascorbic acid) • 1) Vitamin C plays an important role in healing of cuts & wounds. It is necessary for the formation of collagen (a kind of protein) which acts as cementing material in healing of cuts & wounds. • 2) Vitamin C increases the absorption of dietary iron & calcium in the body.
  • 136. 8/3/2016 Prof.Dr.R.R.Deshpande 136 Functions of vitamin C (Ascorbic acid) • 3) Vitamin C prevents scurvy which causes the decay of gums & teeth. • 4) Vitamin C helps in releasing certain hormones which help the body to deal with physical & mental tensions
  • 139. Scurvy Skin bleeding 8/3/2016 Prof.Dr.R.R.Deshpande 139
  • 140. 8/3/2016 Prof.Dr.R.R.Deshpande 140 General characters of vitamin B & C • Both vitamin B & C are soluble in water • Both vitamin B & C are not stored in the body • Both vitamin B & C are destroyed by cooking
  • 141. 8/3/2016 Prof.Dr.R.R.Deshpande 141 Ascorbic acid (Vitamin C) is the most unstable vitamin • 1) Ascorbic acid is easily destroyed by heat, ageing, drying, storing & oxidation • • 2) Ascorbic acid is highly soluble in water. Therefore, when chopped vegetables are washed or when cooking water is discarded, the ascorbic acid is lost.
  • 147. Prof.Dr.R.R.Deshpande • Sharing of Knowledge • FOR • Propagating Ayurved 8/3/2016 147Prof.Dr.R.R.Deshpande