This document discusses bariatric surgery and provides information about preoperative evaluation and management of obese patients undergoing such procedures. It defines terms like BMI, ideal body weight and comorbidities associated with obesity. It emphasizes the importance of a multidisciplinary preoperative assessment, including evaluation of pulmonary, cardiac, endocrine and airway status. Risk scoring systems to predict mortality are presented. Intraoperative management challenges like difficult intubation are also addressed.
This document discusses bariatric surgery and considerations for anesthesiologists. It begins by defining obesity and its health risks. It then discusses the types of bariatric surgeries available and their indications and contraindications. Key considerations for anesthesiologists are the pathophysiological changes in obese patients that affect respiratory, cardiovascular, gastrointestinal and other body systems. Proper positioning, airway management, and drug dosing tailored to the patient's lean body weight versus total body weight are emphasized. Close monitoring is needed during induction, maintenance and emergence from anesthesia due to risks like regurgitation and hypoxemia.
Anaesthesia for morbidly Obese Patients and Bariatric Surgerywww.slideworld.org
This document discusses anaesthesia considerations for morbidly obese patients undergoing bariatric surgery. It defines morbid obesity and covers related pathophysiology involving various organ systems. Challenges include reduced pulmonary function and increased risk of obstructive sleep apnea. Preoperative evaluation focuses on cardiopulmonary assessment and optimizing medical comorbidities. Intraoperative care requires specialized positioning, monitoring, airway management and ventilation techniques to address obesity-related risks like hypoxemia and aspiration.
Bariatric surgery is used to treat morbid obesity through restrictive or malabsorptive procedures like gastric bypass. Anesthesia for bariatric surgery requires special considerations due to patient comorbidities and positioning. Obese patients have increased volumes of distribution and drug dosing is often based on lean or adjusted body weight. Careful attention must be paid to fluid management, ventilation, and emergence from anesthesia due to postoperative pulmonary risks in these patients.
Obesity can impact patient health in several ways relevant to anaesthesia. It is associated with reduced lung capacity and increased risk of respiratory conditions like sleep apnea. It can also impact the cardiovascular system by increasing blood pressure and risk of blood clots. Pre-operative evaluation of obese patients should screen for respiratory diseases and risk of venous thromboembolism. Tests like spirometry and overnight oximetry may be useful, and treatment of conditions like sleep apnea can reduce peri-operative risk. Airway management may also be complicated in obese patients and appropriate preparation is important.
This document discusses anesthesia considerations for bariatric surgery. It defines obesity and lists common comorbidities like diabetes and hypertension. Bariatric surgery procedures aim to induce weight loss and resolve medical conditions. Risks include respiratory complications from reduced lung capacity and obesity hypoventilation syndrome. Preoperative evaluation assesses the airway, cardiovascular and pulmonary systems, sleep apnea risk, and use of weight loss medications. Polysomnography is used to diagnose sleep apnea severity.
The document discusses anesthesia considerations for bariatric surgery. It notes that obesity is associated with various comorbidities affecting the respiratory, cardiovascular, gastrointestinal and other body systems. The anesthesia plan involves a thorough preoperative evaluation of the patient's airway, cardiac function, respiratory status, risk of venous thromboembolism, and metabolic/nutritional abnormalities. Careful dosing of anesthetic drugs based on lean or total body weight is also required. The goal of anesthesia is to safely induce and maintain anesthesia for bariatric surgery while addressing the unique health risks faced by obese patients.
This document discusses anaesthetic considerations for morbidly obese patients. Key points include:
- Morbid obesity is defined as a body weight more than twice the ideal body weight or 100kg heavier.
- It is associated with increased risks of cardiovascular, respiratory, endocrine and other medical conditions.
- Anaesthetic challenges include difficulties with airway management, ventilation, increased drug volumes of distribution and altered pharmacokinetics.
- Thorough pre-operative evaluation of co-morbidities and risks is important for planning anaesthesia.
Anaesthesia for morbidly obese patients and bariatric surgery- Dr.Sandeepdeepmbbs04
This document discusses anaesthesia considerations for morbidly obese patients undergoing bariatric surgery. It defines morbid obesity and discusses the increased prevalence worldwide. It explores the physiological changes that occur with obesity, including effects on the cardiovascular, respiratory, gastrointestinal and renal systems. It also discusses specific conditions like obstructive sleep apnea. The document provides guidelines on preoperative evaluation and optimization of morbidly obese patients, including screening for common comorbidities. It discusses modifications to anaesthetic management including dosing based on adjusted body weight and techniques to address challenges with airway management and positioning for this patient population.
This document discusses bariatric surgery and considerations for anesthesiologists. It begins by defining obesity and its health risks. It then discusses the types of bariatric surgeries available and their indications and contraindications. Key considerations for anesthesiologists are the pathophysiological changes in obese patients that affect respiratory, cardiovascular, gastrointestinal and other body systems. Proper positioning, airway management, and drug dosing tailored to the patient's lean body weight versus total body weight are emphasized. Close monitoring is needed during induction, maintenance and emergence from anesthesia due to risks like regurgitation and hypoxemia.
Anaesthesia for morbidly Obese Patients and Bariatric Surgerywww.slideworld.org
This document discusses anaesthesia considerations for morbidly obese patients undergoing bariatric surgery. It defines morbid obesity and covers related pathophysiology involving various organ systems. Challenges include reduced pulmonary function and increased risk of obstructive sleep apnea. Preoperative evaluation focuses on cardiopulmonary assessment and optimizing medical comorbidities. Intraoperative care requires specialized positioning, monitoring, airway management and ventilation techniques to address obesity-related risks like hypoxemia and aspiration.
Bariatric surgery is used to treat morbid obesity through restrictive or malabsorptive procedures like gastric bypass. Anesthesia for bariatric surgery requires special considerations due to patient comorbidities and positioning. Obese patients have increased volumes of distribution and drug dosing is often based on lean or adjusted body weight. Careful attention must be paid to fluid management, ventilation, and emergence from anesthesia due to postoperative pulmonary risks in these patients.
Obesity can impact patient health in several ways relevant to anaesthesia. It is associated with reduced lung capacity and increased risk of respiratory conditions like sleep apnea. It can also impact the cardiovascular system by increasing blood pressure and risk of blood clots. Pre-operative evaluation of obese patients should screen for respiratory diseases and risk of venous thromboembolism. Tests like spirometry and overnight oximetry may be useful, and treatment of conditions like sleep apnea can reduce peri-operative risk. Airway management may also be complicated in obese patients and appropriate preparation is important.
This document discusses anesthesia considerations for bariatric surgery. It defines obesity and lists common comorbidities like diabetes and hypertension. Bariatric surgery procedures aim to induce weight loss and resolve medical conditions. Risks include respiratory complications from reduced lung capacity and obesity hypoventilation syndrome. Preoperative evaluation assesses the airway, cardiovascular and pulmonary systems, sleep apnea risk, and use of weight loss medications. Polysomnography is used to diagnose sleep apnea severity.
The document discusses anesthesia considerations for bariatric surgery. It notes that obesity is associated with various comorbidities affecting the respiratory, cardiovascular, gastrointestinal and other body systems. The anesthesia plan involves a thorough preoperative evaluation of the patient's airway, cardiac function, respiratory status, risk of venous thromboembolism, and metabolic/nutritional abnormalities. Careful dosing of anesthetic drugs based on lean or total body weight is also required. The goal of anesthesia is to safely induce and maintain anesthesia for bariatric surgery while addressing the unique health risks faced by obese patients.
This document discusses anaesthetic considerations for morbidly obese patients. Key points include:
- Morbid obesity is defined as a body weight more than twice the ideal body weight or 100kg heavier.
- It is associated with increased risks of cardiovascular, respiratory, endocrine and other medical conditions.
- Anaesthetic challenges include difficulties with airway management, ventilation, increased drug volumes of distribution and altered pharmacokinetics.
- Thorough pre-operative evaluation of co-morbidities and risks is important for planning anaesthesia.
Anaesthesia for morbidly obese patients and bariatric surgery- Dr.Sandeepdeepmbbs04
This document discusses anaesthesia considerations for morbidly obese patients undergoing bariatric surgery. It defines morbid obesity and discusses the increased prevalence worldwide. It explores the physiological changes that occur with obesity, including effects on the cardiovascular, respiratory, gastrointestinal and renal systems. It also discusses specific conditions like obstructive sleep apnea. The document provides guidelines on preoperative evaluation and optimization of morbidly obese patients, including screening for common comorbidities. It discusses modifications to anaesthetic management including dosing based on adjusted body weight and techniques to address challenges with airway management and positioning for this patient population.
Obesity is a global health problem with increasing prevalence. It is associated with numerous medical complications and increases surgical risk. Anesthetizing obese patients requires special considerations. Due to reduced lung volumes, obese patients are more prone to hypoxemia and respiratory failure. Airway management can also be difficult due to limited mobility and excess soft tissue. Careful preoperative optimization is important given increased cardiovascular and metabolic risks. During anesthesia, dosing of some drugs should be based on ideal body weight rather than total weight.
Peri-operative management of obese patients undergoing bariatric surgery.pptdrtanveeralamkhan
This document discusses the peri-operative management of obese surgical patients and bariatric surgery. It covers obesity classification and pathophysiology, types of bariatric surgery procedures, and recommendations for pre-operative, intra-operative, and post-operative patient care and management. The key aspects of peri-operative care include screening for comorbidities, regional anesthesia preference over general anesthesia, careful airway management and neuromuscular blockade during surgery, and post-op analgesia, thromboembolism prophylaxis, and mobilization support.
This presentation explains change physiological changes occurs in obesity. Which pre op investigation should be done of those patient before scheduling them for surgery. What in the end anaesthesia consideration of obesity with post op care.
This document discusses obesity, its causes and health risks, and the evidence that bariatric surgery is an effective treatment option. It provides details on different types of bariatric surgeries performed since the 1950s and their effectiveness based on clinical studies. It also outlines patient selection criteria and risks for bariatric surgery, and discusses how surgery works to induce weight loss and resolve obesity-related diseases through hormonal and other physiological changes.
1) Obesity is defined using Body Mass Index (BMI) and is a multifactorial condition resulting from excess caloric intake and lack of physical activity.
2) A study in Basrah, Iraq found that 55.1% of adults were either overweight or obese, with women more affected than men.
3) Obstructive sleep apnea (OSA) is common in obese patients, with one study finding 76% of obese patients having undiagnosed OSA. Non-surgical management includes lifestyle changes and various pharmacotherapies.
This document discusses anesthetic concerns for morbidly obese patients undergoing surgery. It notes that obesity can impact the respiratory, cardiovascular, hepatic, renal, and other body systems. Anesthesiologists must consider issues like difficult airway management, restrictive lung disease, increased risk of aspiration, appropriate drug dosing based on lean body weight, special equipment needs, and perioperative optimization for comorbidities. Preoperative planning is essential for the safe anesthetic management of morbidly obese surgical patients.
BCC4: Michael Parr on ICU - Surviving Trauma GuidelinesSMACC Conference
Michael Parr, director of Liverpool ICU in Australia, speaks about "Surviving Trauma Guidelines". He does so through the use of an interesting case of a patient admitted to ICU following a MVA. This educational podcast was recorded at BCC4.
This document presents definitions agreed upon by experts for intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). IAH is defined as an intra-abdominal pressure of 12 mmHg or higher and is graded based on severity. ACS occurs when IAH is over 20 mmHg and is associated with new organ dysfunction. The definitions standardize measurement of intra-abdominal pressure via bladder at 25 ml saline and establish abdominal perfusion pressure as key. Primary ACS originates in the abdomen while secondary ACS occurs elsewhere and can recur after initial treatment.
The document discusses preoperative evaluation, which involves assessing a patient's medical status and anaesthetic risks before surgery through history, examinations, tests, and a multidisciplinary team to reduce morbidity and mortality. It outlines the goals, steps, assessments including airway and exercise tolerance, role of physicians and nurses, and concludes that a combined effort can significantly reduce surgical risks.
Mr. Lung is a 78-year-old man scheduled for a 4-hour L3-5 laminectomy and fusion who has severe COPD, diabetes, hypertension, and a 40 pack-year smoking history. He takes medications for his COPD and other conditions and is functionally independent but dyspneic with exertion. Preoperative evaluation shows he is at increased risk for postoperative pulmonary complications according to several risk prediction models. Recommendations are made for postoperative lung expansion techniques and monitoring to help mitigate his risks.
initial assessment of critically ill patients(PRESENTED AT IMA HOUSE,CUTTACK)Prerna Biswal
1. A 52-year-old male presented with severe breathlessness and sweating for 5 hours and was admitted to the ICU in a critically ill state.
2. Initial assessment and resuscitation focused on the ABCDE approach to address airway, breathing, circulation, disability and exposure/environment. Basic investigations were sent.
3. The patient was diagnosed with an acute exacerbation of COPD. He was treated with oxygen, steroids, bronchodilators and antibiotics. Due to worsening, non-invasive ventilation was added and the patient showed gradual improvement.
Enhanced external counterpulsation (eecp) role inMonir zaman
Enhanced external counterpulsation (EECP) involves the use of inflatable cuffs wrapped around the lower extremities that are synchronized with the cardiac cycle to improve coronary perfusion. A study investigated EECP in patients with heart failure and found it improved exercise duration but not peak oxygen consumption compared to medical therapy alone. While EECP appears safe, more research is still needed to determine its efficacy in treating heart failure.
The document discusses the process and objectives of pre-anesthesia checkups (PACs). A PAC involves assessing a patient's medical history, conducting a physical exam, and developing an anesthesia plan. It aims to evaluate perioperative risk and ensure a patient can safely tolerate anesthesia. Key parts of the evaluation include reviewing the cardiovascular, respiratory, and other organ systems, as well as performing airway exams and risk assessments. The PAC provides important information to inform anesthesia management and optimize patient safety and outcomes.
1. The patient is experiencing dynamic hyperinflation from an acute asthma exacerbation, evidenced by unchanged plateau pressures but rising peak airway pressures over time.
2. Additional therapies needed include bronchodilators to reduce airflow obstruction and respiratory muscle fatigue, as well as optimizing ventilator settings to decrease the work of breathing.
3. Dynamic hyperinflation can lead to hypotension and cardiovascular instability in acute asthma or COPD exacerbations if not addressed.
This document discusses stress testing, which measures the heart's response to external stress. There are two main types of stress testing - exercise testing using treadmills or bicycles, and pharmacological testing using medications. Stress testing can help diagnose coronary artery disease, evaluate functional capacity, and assess treatment effects. The document outlines guidelines for indications, contraindications, and interpretations of different stress test results. Key measurements taken during stress tests include ECG, exercise capacity, symptoms, blood pressure, and heart rate response.
Pulmonary embolism (PE) is a common and potentially fatal cardiovascular condition caused by blood clots in the lungs. The document discusses the classification, pathophysiology, risk factors, clinical features, diagnostic testing and management of PE. Key points include that PE has a 15% fatality rate if untreated, but mortality decreases to around 10% with anticoagulation therapy. Rapid risk stratification and treatment of high-risk PE cases with thrombolysis, surgery or other interventions is important for reducing mortality.
This document provides an overview of preoperative evaluation and preparation. It discusses taking a thorough patient history and conducting a physical exam, with a focus on assessing the airway and risk factors. Preoperative tests and investigations are recommended based on patient age and type of surgery. Risk stratification tools like the ASA classification and cardiac risk indices are presented. Guidelines are provided for medication management and NPO restrictions prior to surgery. The goals of preoperative evaluation are identified as optimizing patient health and reducing perioperative risks.
This document discusses the cardiovascular, respiratory, renal, hepatic, and other physiologic effects of pneumoperitoneum during laparoscopic surgery. Pneumoperitoneum, or insufflation of carbon dioxide gas into the abdominal cavity, can cause hemodynamic changes such as decreased venous return and cardiac output. It can also decrease lung volumes and impair respiratory function. These effects are more pronounced in elderly or debilitated patients undergoing laparoscopic surgery. The document emphasizes the importance of intraoperative monitoring and management strategies to optimize patient hemodynamics and ventilation during pneumoperitoneum, especially in high-risk patients.
This document provides an outline for a presentation on acute lung injury (ALI). It defines ALI and describes the pathological process. Some key points include: ALI results from direct or indirect lung injury and involves two pathological phases. Common causes include sepsis or trauma. Symptoms include rapid breathing and low blood oxygen levels. Diagnosis involves tests like chest x-rays and blood gases. Treatment involves mechanical ventilation, fluid management, and prone positioning. Complications can include pulmonary fibrosis or cardiac issues. Nursing care focuses on managing breathing patterns, gas exchange, and reducing patient anxiety.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Obesity is a global health problem with increasing prevalence. It is associated with numerous medical complications and increases surgical risk. Anesthetizing obese patients requires special considerations. Due to reduced lung volumes, obese patients are more prone to hypoxemia and respiratory failure. Airway management can also be difficult due to limited mobility and excess soft tissue. Careful preoperative optimization is important given increased cardiovascular and metabolic risks. During anesthesia, dosing of some drugs should be based on ideal body weight rather than total weight.
Peri-operative management of obese patients undergoing bariatric surgery.pptdrtanveeralamkhan
This document discusses the peri-operative management of obese surgical patients and bariatric surgery. It covers obesity classification and pathophysiology, types of bariatric surgery procedures, and recommendations for pre-operative, intra-operative, and post-operative patient care and management. The key aspects of peri-operative care include screening for comorbidities, regional anesthesia preference over general anesthesia, careful airway management and neuromuscular blockade during surgery, and post-op analgesia, thromboembolism prophylaxis, and mobilization support.
This presentation explains change physiological changes occurs in obesity. Which pre op investigation should be done of those patient before scheduling them for surgery. What in the end anaesthesia consideration of obesity with post op care.
This document discusses obesity, its causes and health risks, and the evidence that bariatric surgery is an effective treatment option. It provides details on different types of bariatric surgeries performed since the 1950s and their effectiveness based on clinical studies. It also outlines patient selection criteria and risks for bariatric surgery, and discusses how surgery works to induce weight loss and resolve obesity-related diseases through hormonal and other physiological changes.
1) Obesity is defined using Body Mass Index (BMI) and is a multifactorial condition resulting from excess caloric intake and lack of physical activity.
2) A study in Basrah, Iraq found that 55.1% of adults were either overweight or obese, with women more affected than men.
3) Obstructive sleep apnea (OSA) is common in obese patients, with one study finding 76% of obese patients having undiagnosed OSA. Non-surgical management includes lifestyle changes and various pharmacotherapies.
This document discusses anesthetic concerns for morbidly obese patients undergoing surgery. It notes that obesity can impact the respiratory, cardiovascular, hepatic, renal, and other body systems. Anesthesiologists must consider issues like difficult airway management, restrictive lung disease, increased risk of aspiration, appropriate drug dosing based on lean body weight, special equipment needs, and perioperative optimization for comorbidities. Preoperative planning is essential for the safe anesthetic management of morbidly obese surgical patients.
BCC4: Michael Parr on ICU - Surviving Trauma GuidelinesSMACC Conference
Michael Parr, director of Liverpool ICU in Australia, speaks about "Surviving Trauma Guidelines". He does so through the use of an interesting case of a patient admitted to ICU following a MVA. This educational podcast was recorded at BCC4.
This document presents definitions agreed upon by experts for intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). IAH is defined as an intra-abdominal pressure of 12 mmHg or higher and is graded based on severity. ACS occurs when IAH is over 20 mmHg and is associated with new organ dysfunction. The definitions standardize measurement of intra-abdominal pressure via bladder at 25 ml saline and establish abdominal perfusion pressure as key. Primary ACS originates in the abdomen while secondary ACS occurs elsewhere and can recur after initial treatment.
The document discusses preoperative evaluation, which involves assessing a patient's medical status and anaesthetic risks before surgery through history, examinations, tests, and a multidisciplinary team to reduce morbidity and mortality. It outlines the goals, steps, assessments including airway and exercise tolerance, role of physicians and nurses, and concludes that a combined effort can significantly reduce surgical risks.
Mr. Lung is a 78-year-old man scheduled for a 4-hour L3-5 laminectomy and fusion who has severe COPD, diabetes, hypertension, and a 40 pack-year smoking history. He takes medications for his COPD and other conditions and is functionally independent but dyspneic with exertion. Preoperative evaluation shows he is at increased risk for postoperative pulmonary complications according to several risk prediction models. Recommendations are made for postoperative lung expansion techniques and monitoring to help mitigate his risks.
initial assessment of critically ill patients(PRESENTED AT IMA HOUSE,CUTTACK)Prerna Biswal
1. A 52-year-old male presented with severe breathlessness and sweating for 5 hours and was admitted to the ICU in a critically ill state.
2. Initial assessment and resuscitation focused on the ABCDE approach to address airway, breathing, circulation, disability and exposure/environment. Basic investigations were sent.
3. The patient was diagnosed with an acute exacerbation of COPD. He was treated with oxygen, steroids, bronchodilators and antibiotics. Due to worsening, non-invasive ventilation was added and the patient showed gradual improvement.
Enhanced external counterpulsation (eecp) role inMonir zaman
Enhanced external counterpulsation (EECP) involves the use of inflatable cuffs wrapped around the lower extremities that are synchronized with the cardiac cycle to improve coronary perfusion. A study investigated EECP in patients with heart failure and found it improved exercise duration but not peak oxygen consumption compared to medical therapy alone. While EECP appears safe, more research is still needed to determine its efficacy in treating heart failure.
The document discusses the process and objectives of pre-anesthesia checkups (PACs). A PAC involves assessing a patient's medical history, conducting a physical exam, and developing an anesthesia plan. It aims to evaluate perioperative risk and ensure a patient can safely tolerate anesthesia. Key parts of the evaluation include reviewing the cardiovascular, respiratory, and other organ systems, as well as performing airway exams and risk assessments. The PAC provides important information to inform anesthesia management and optimize patient safety and outcomes.
1. The patient is experiencing dynamic hyperinflation from an acute asthma exacerbation, evidenced by unchanged plateau pressures but rising peak airway pressures over time.
2. Additional therapies needed include bronchodilators to reduce airflow obstruction and respiratory muscle fatigue, as well as optimizing ventilator settings to decrease the work of breathing.
3. Dynamic hyperinflation can lead to hypotension and cardiovascular instability in acute asthma or COPD exacerbations if not addressed.
This document discusses stress testing, which measures the heart's response to external stress. There are two main types of stress testing - exercise testing using treadmills or bicycles, and pharmacological testing using medications. Stress testing can help diagnose coronary artery disease, evaluate functional capacity, and assess treatment effects. The document outlines guidelines for indications, contraindications, and interpretations of different stress test results. Key measurements taken during stress tests include ECG, exercise capacity, symptoms, blood pressure, and heart rate response.
Pulmonary embolism (PE) is a common and potentially fatal cardiovascular condition caused by blood clots in the lungs. The document discusses the classification, pathophysiology, risk factors, clinical features, diagnostic testing and management of PE. Key points include that PE has a 15% fatality rate if untreated, but mortality decreases to around 10% with anticoagulation therapy. Rapid risk stratification and treatment of high-risk PE cases with thrombolysis, surgery or other interventions is important for reducing mortality.
This document provides an overview of preoperative evaluation and preparation. It discusses taking a thorough patient history and conducting a physical exam, with a focus on assessing the airway and risk factors. Preoperative tests and investigations are recommended based on patient age and type of surgery. Risk stratification tools like the ASA classification and cardiac risk indices are presented. Guidelines are provided for medication management and NPO restrictions prior to surgery. The goals of preoperative evaluation are identified as optimizing patient health and reducing perioperative risks.
This document discusses the cardiovascular, respiratory, renal, hepatic, and other physiologic effects of pneumoperitoneum during laparoscopic surgery. Pneumoperitoneum, or insufflation of carbon dioxide gas into the abdominal cavity, can cause hemodynamic changes such as decreased venous return and cardiac output. It can also decrease lung volumes and impair respiratory function. These effects are more pronounced in elderly or debilitated patients undergoing laparoscopic surgery. The document emphasizes the importance of intraoperative monitoring and management strategies to optimize patient hemodynamics and ventilation during pneumoperitoneum, especially in high-risk patients.
This document provides an outline for a presentation on acute lung injury (ALI). It defines ALI and describes the pathological process. Some key points include: ALI results from direct or indirect lung injury and involves two pathological phases. Common causes include sepsis or trauma. Symptoms include rapid breathing and low blood oxygen levels. Diagnosis involves tests like chest x-rays and blood gases. Treatment involves mechanical ventilation, fluid management, and prone positioning. Complications can include pulmonary fibrosis or cardiac issues. Nursing care focuses on managing breathing patterns, gas exchange, and reducing patient anxiety.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
4. DEFINITIONSBODY MASS INDEX BMI ( Quetelet’s Index):
WEIGHT(kg)/HEIGHT (m2)
BMI
SEVERE OBESITY 35-39.9
MORBID OBESITY > 40
SUPER OBESITY > 50
WEIGHT FEMALE MALE
IDEAL 19.1-25.8 20.7-26.4
MARGINAL OVERWEIGHT 25.9-27.2 26.5-27.8
OVERWEIGHT 27.3-32.3 27.9-31.3
OBESE 32.4-34.9 31.4-34.9
5. IDEAL BODY WEIGHT
Ideal Body Weight: IBW (Lorentz) :
IBW = X + 0,91 (height in cm - 152,4)
Female : X = 45, 5
Male : X = 50
More easy to remember
IBW (kg) = Height (cm) - 100 in MALE
IBW (kg) = Height (cm) - 110 in FEMALE
8. COMORBID DISEASE
BURDEN
PATIENTS %
NO COMORBIDITIES 137 14
1 COMORBID DISEASE 263 22
2 COMORBID DISEASE 454 38
3 COMORBID DISEASE 284 23
4 OR MORE COMORBID DISEASE 71 6
COMORBID DISEASE PREVALENCE IN 1,210 PATIENTS
FOR BARIATRIC SURGERY
9. • Hypertension
• Diabetes
• Venous stasis disease
• pseudotumor cerebri
• OSA and/ or OHS
no major comorbid disease
1 or +
Comorbidities on mortality and complications after gastric bypass
10. 32 + 6 BMI 0.001 35 + 8
0.2% Mortality 0.0032 2.3%
1.2% Leak rate 0.0032 4.1%
1.4% Surgical Infection 0.0133 3.9%
68% Excess weight loss 0.001 62%
Comorbidities on mortality and complications after gastric bypass
11. INDICATIONS/CONTRAINDICATIONS
1- Individuals with BMI > 40 Kg/m2 who have failed
conventional weight-control programs.
2- Individuals with a BMI between 35 and 39.9 kg/m2 who
have high risk health problems affecting lifestyle ( i.e,
employment or mobility)
CONTRAINDICATIONS:
1- Severe mental illness resulting in psychosis.
2- Substance abuse.
3- Major organ failure.
13. PULMONARY FUNCTION
Reduced compliance of lung and chest wall.
Reduced lung volume.
Increased respiratory resistance.
Increased work of breathing.
14. RESPIRATORY SYSTEM
Dyspnea with exertion.
Significant impairement of pulmonary function ,
often with few symptoms.
Reduction in lung volumes atelectasis, airway
closure hypoxia.
Reduction of functional residual capacity rapid
desaturation during apnea at anesthesia induction.
15. PRE OPERATIVE PULMONARY EVALUATION
Preoperative pulmonary function tests are indicated for
patients with
1- documented pulmonary problems.
2- limited performance status because of dyspnea.
3- BMI > 60 kg/m2.
Arterial blood gas hypoventilation in severely obese
patients.
Identify risk for postoperative hypoxia.
Facilitate postoperative respiratory care.
16. PULMONARY EVALUATION
Forced vital capacity varies inversely with BMI.
Patients with very high BMI , even when
asymptomatic will have major reductions in lung
function
Patients with preoperative pulmonary impairement
Significant risk for hypoxia during the immediate
postoperative period Bi-level positive airway pressure
in recovery room preserve oxygenation
No evidence of gastric pouch problems
related to its use
17. OBSTRUCTIVE SLEEP APNEA ( OSA)
75 % of PATIENTS
The prevalence increases with BMI.
OSA is an independent risk factor
for metabolic syndrome ( impaired glucose tolerance-insulin
resistance and dyslipidaemia)
for all-cause mortality
18. OBSTRUCTIVE SLEEP APNEA ( OSA)
Detailed clinical history is mandatory.
Symptoms: - Heavy snoring
- Witnessed apnea.
- Excessive daytime somnolence.
- Lack of restful sleep.
Questionnaire: STOP, Berlin, ASA Check list.
Patients with suspected OSA preoperative sleep study
(Polysomnography)& titration of CPAP.
Consequence of OSA can be reversed by CPAP
19. STOP QUESTIONNAIRE
STOP Questionnaire is concise and easy –to use screening tool for OSA.
1-Do you snore loudly?
2- Do you often feel tired , fatigued or sleepy during day time?
3- Do you have or are you being treated for high blood pressure?
4- Has any one observed you stop breathing during sleep?
Combined with
BMI
age
neck size & gender,
STOP = high sensitivity
especially for patients
with moderate to severe OSA
19
20. Validation of the Berlin Questionnaire and American Society of
Anesthesiologists Checklist as screening tools for obstructive
sleep apnea in surgical patients
The Berlin questionnaire and ASA checklist
demonstrated a moderately high level of sensitivity
for OSA screening.
STOP Questionnaire and the ASA checklist were able
to indentify the patients who were likely to develop
postoperative complications.
21. OBSTRUCTIVE SLEEP APNEA ( OSA) & POLYSOMNOGRAPHY
Routine preoperative PSG
cost effective
lacking improved outcome
=> not part of ASA practice guidelines for the
perioperative management of patients with OSA.
ASA practice guidelines for the perioperative management
of patients with obstructive sleep apnea.
A referral for PSG study should
be individualized.
22. POTENTIALLY LIFE –THREATENING SLEEP APNEA IS
UNRECOGNIZED WITHOUT AGGRESSIVE EVALUATION.
Era 1= OSA evaluation based on clinical parameters.
Era2= Mandatory OSA evaluation for all patients
23. POTENTIALLY LIFE –THREATENING SLEEP APNEA IS
UNRECOGNIZED WITHOUT AGGRESSIVE EVALUATION.
OSA is grossly underdiagnosed.
Clinical evaluation misses a % of patients with OSA.
Mandatory testing with Polysomnography
24. CPAP or BiPAP
DURATION
EFFECT
2 weeks correct abnormal ventilatory drive in obese
hypercapneic patients
3 weeks improves left ventricular ejection function
in patients with CHF
4 weeks
reduce HR, BP & 35% increase in EF in
patients with CHF.
4- 6 weeks reduce tongue volume & increase
pharyngeal space
8 weeks improved morning hypertension
3-6 months reduced pulmonary hypertension
24
25. PREOPERATIVE SMOKING HABITS AND
POSTOPERATIVE PULMONARY COMPLICATIONS
Smoking is a proven risk factor for postoperative
pulmonary complications.
The risk declines with cessation of smoking for 8
weeks before surgery.
Most bariatric programs insist on abstinence from
smoking before-hand.
28. CARDIAC EVALUATION
Cardiac evaluation can be difficult to ascertain.
Clinical history limited mobility.
Clinical examination muffled heart sounds.
short thick neck conceal JVP
SEDENTARY LIFE peripheral edema.
Functional capacity 4 METS =climbing a flight of stairs
=moderate functional capacity.
The Revised Cardiac risk is commonly used to assess
cardiac risk in patients undergoing non cardiac surgery
29. Derivation and prospective validation of a simple index for
prediction of cardiac risk of major non cardiac surgery
1 High risk surgery
2 IHD.
3 CHF.
4 Cerebrovascular disease.
5 IDDM
6 Renal insufficiency.
IF YES = 1 POINT/ITEM
SCORE RISK
0 0.4%
1 0.9%
2 6.6%
3 11%
31. CARDAIC EVALUATION
Unknown or limited exercise tolerance or with any
significant co-morbidity Cardiopulmonary
exercise testing( CPEX).
Unable to exercise cardiologist for alternative
provocative cardiac testing.
34. Obstructive sleep apnea is not a risk factor for difficult intubation in
180 morbidly obese patients
Risk factors :
Mallampati Score > 3
male gender
AIRWAY ASSESSMENT
35. AIRWAY MANAGEMENT
Optimal positioning;
- Ramped position by placing blankets under the patient’s
upper body.
- 25-30 reversed Trendelenburg, head up or the near
sitting position
Availability of different airway
management options
38. ENDOCRINE FUNCTION
15 -20% of morbidly obese patients have type 2
diabetes.
Glucose control requires close preoperative attention.
Hyperglycemia (> 220 mg/dl) inhibits many important
functions of polymorphonuclear leucocytes.
Good preoperative glycemic control in terms of HbA1c
below 7% is associated with a reduced infection risk .
Specialist consultation will be necessary.
Thyroid function tests ; Adrenal function tests ( if
39. SCORING SYSTEMS
Obesity Surgery Mortality Risk Score ( OS-MRS):
Validated scoring system specific to obese patients
undergoing bariatric surgery ( 1 point for each)
1- BMI > 50 kg/m2. 2- Male gender.
3- Systemic hypertension. 4- Risk factors for pulmonary embolism.
5- Age > 45
. SCORE RISK MORTALITY
0-1 LOW 0.31%
2-3 INTERMEDIATE 1.9%
4-5 HIGH 7.56%