Background Phenylketonuria is an inherited disease which re.pdf
•
0 likes•3 views
Background: Phenylketonuria is an inherited disease which results from the lack of the enzyme phenylalanine hydroxylase (PAH). The PAH enzyme catalyzes the first step in the degradation of phenylalanine, as shown in Figure 30.1. In the phenylketonuric patient, phenylalanine accumulates which is eventually transaminated to phenylpyruvate, a phenylketone compound. Excess phenylpyruvate accumulates in the blood and urine and has the effect of causing mental retardation if untreated. Screening programs identify PKU babies at birth, and treatment consists of a low phenylalanine diet until maturation of the brain is completed. The structure and biochemical properties of the PAH enzyme have been well-studied.The gene for PAH has been isolated and has been localized to chromosome 12. The PAH enzyme is a protein 451 amino acids in length with a molecular weight of 51,900 daltons. More than 60 different mutant genes giving rise to nonfunctional PAH proteins have been identified in PKU patients. Question:Kinetic data in which PAH activity is compared with and without preincubation with phenylalanine is shown in Figure 30.3. Give a structural basis for the interpretation of these data. Figure 30.1. Phenylalanine and tyrosine meravurior. an essential cofactor for phenylalanine hydroxylase. 95Figure 30.1. Phenylalanine and tyrosmio ..... an essential cofactor for phenylalanine hydroxylase. 95.
Report
Share
Report
Share
Download to read offline
Recommended
phenylketonuria
PKU is an autosomal recessive genetic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase. This enzyme is necessary to break down the amino acid phenylalanine. Without it, phenylalanine builds up to toxic levels in the blood and brain, which can lead to intellectual disabilities if left untreated. PKU is typically detected via newborn screening and treated through a lifelong low-phenylalanine diet. Some cases may also be managed through medication. Strict dietary control is necessary before and during pregnancy for women with PKU to prevent complications in their babies.
Phenylketonuria Ppt
Phenylketonuria (PKU) is a genetic disorder caused by a mutation that prevents the breakdown of phenylalanine. This allows phenylalanine levels to accumulate in the blood and brain, which can cause intellectual disabilities if left untreated. The condition is usually diagnosed via newborn screening, which tests for high phenylalanine levels. Treatment requires a lifelong low-phenylalanine diet to prevent cognitive issues and other health problems associated with elevated phenylalanine. Strict dietary control is necessary to manage PKU and avoid complications.
phenylketonuria
Phenylketonuria (PKU) is a genetic disorder that causes the buildup of phenylalanine in the body due to the lack of the enzyme phenylalanine hydroxylase. This enzyme is needed to break down phenylalanine from the diet. The buildup of phenylalanine can lead to intellectual disability if not treated through a low-protein diet. PKU results from mutations in the PAH gene which provides instructions for making the phenylalanine hydroxylase enzyme. The disorder was first discovered in 1934 and can now be diagnosed through newborn screening to help prevent complications through early treatment.
Pku concept map dr-kumar-ponnusamy-biochemistry-genetics-usmle-preparatory-co...
Dr. Kumar Ponnusamy and colleagues aim to delineate the molecular and biochemical basis of phenylketonuria (PKU), its diagnosis and management, and facilitate online teaching about it. PKU is an autosomal recessive genetic disorder caused by a mutation that renders the enzyme phenylalanine hydroxylase nonfunctional. This prevents the conversion of phenylalanine to tyrosine, leading to accumulation of phenylalanine and its toxic byproducts in the central nervous system, which can cause severe mental retardation if left untreated. Management of PKU involves a low-phenylalanine diet, avoiding aspartame, and careful control of phenylalanine levels during pregnancy to prevent adverse effects on fetal development.
Phenylketonuria #
A six-year-old boy was referred to the hospital for aggressive behavior and developmental delays. He was found to have phenylketonuria (PKU), an autosomal recessive disorder caused by a mutation in the PAH gene which results in high phenylalanine levels and intellectual disability if left untreated. Testing found elevated phenylalanine levels in his blood and urine. PKU must be treated through life with a low-phenylalanine diet to prevent neurological damage, as there is currently no cure. Gene therapy research aims to introduce a functional PAH gene to allow breakdown of phenylalanine in the liver.
Therapeutic applications of Phenylalanine ammonia lyase and Phenylalanine Hyd...
Therapeutic applications of Phenylalanine ammonia lyase and Phenylalanine Hydroxylse in phenylketonuria
Phenylketonuria(pku) new
This presentation is about the a disease , causes and cure.
Also it contains the experiments done on mouse models.I tried to explain it with the help of cathy diagrams.
PKU presentation
Phenylketonuria (PKU) is an inherited disorder caused by a deficiency of the enzyme phenylalanine hydroxylase, resulting in an inability to metabolize the essential amino acid phenylalanine. Left untreated, it can cause severe intellectual disability. It is diagnosed through newborn screening and treated with a phenylalanine-restricted diet. For pregnant women with PKU, careful control of phenylalanine levels through diet is needed to prevent complications in the fetus like intellectual disability and birth defects. The case study describes a woman with mild PKU who was able to deliver a healthy infant by maintaining her phenylalanine-restricted diet during pregnancy.
Recommended
phenylketonuria
PKU is an autosomal recessive genetic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase. This enzyme is necessary to break down the amino acid phenylalanine. Without it, phenylalanine builds up to toxic levels in the blood and brain, which can lead to intellectual disabilities if left untreated. PKU is typically detected via newborn screening and treated through a lifelong low-phenylalanine diet. Some cases may also be managed through medication. Strict dietary control is necessary before and during pregnancy for women with PKU to prevent complications in their babies.
Phenylketonuria Ppt
Phenylketonuria (PKU) is a genetic disorder caused by a mutation that prevents the breakdown of phenylalanine. This allows phenylalanine levels to accumulate in the blood and brain, which can cause intellectual disabilities if left untreated. The condition is usually diagnosed via newborn screening, which tests for high phenylalanine levels. Treatment requires a lifelong low-phenylalanine diet to prevent cognitive issues and other health problems associated with elevated phenylalanine. Strict dietary control is necessary to manage PKU and avoid complications.
phenylketonuria
Phenylketonuria (PKU) is a genetic disorder that causes the buildup of phenylalanine in the body due to the lack of the enzyme phenylalanine hydroxylase. This enzyme is needed to break down phenylalanine from the diet. The buildup of phenylalanine can lead to intellectual disability if not treated through a low-protein diet. PKU results from mutations in the PAH gene which provides instructions for making the phenylalanine hydroxylase enzyme. The disorder was first discovered in 1934 and can now be diagnosed through newborn screening to help prevent complications through early treatment.
Pku concept map dr-kumar-ponnusamy-biochemistry-genetics-usmle-preparatory-co...
Dr. Kumar Ponnusamy and colleagues aim to delineate the molecular and biochemical basis of phenylketonuria (PKU), its diagnosis and management, and facilitate online teaching about it. PKU is an autosomal recessive genetic disorder caused by a mutation that renders the enzyme phenylalanine hydroxylase nonfunctional. This prevents the conversion of phenylalanine to tyrosine, leading to accumulation of phenylalanine and its toxic byproducts in the central nervous system, which can cause severe mental retardation if left untreated. Management of PKU involves a low-phenylalanine diet, avoiding aspartame, and careful control of phenylalanine levels during pregnancy to prevent adverse effects on fetal development.
Phenylketonuria #
A six-year-old boy was referred to the hospital for aggressive behavior and developmental delays. He was found to have phenylketonuria (PKU), an autosomal recessive disorder caused by a mutation in the PAH gene which results in high phenylalanine levels and intellectual disability if left untreated. Testing found elevated phenylalanine levels in his blood and urine. PKU must be treated through life with a low-phenylalanine diet to prevent neurological damage, as there is currently no cure. Gene therapy research aims to introduce a functional PAH gene to allow breakdown of phenylalanine in the liver.
Therapeutic applications of Phenylalanine ammonia lyase and Phenylalanine Hyd...
Therapeutic applications of Phenylalanine ammonia lyase and Phenylalanine Hydroxylse in phenylketonuria
Phenylketonuria(pku) new
This presentation is about the a disease , causes and cure.
Also it contains the experiments done on mouse models.I tried to explain it with the help of cathy diagrams.
PKU presentation
Phenylketonuria (PKU) is an inherited disorder caused by a deficiency of the enzyme phenylalanine hydroxylase, resulting in an inability to metabolize the essential amino acid phenylalanine. Left untreated, it can cause severe intellectual disability. It is diagnosed through newborn screening and treated with a phenylalanine-restricted diet. For pregnant women with PKU, careful control of phenylalanine levels through diet is needed to prevent complications in the fetus like intellectual disability and birth defects. The case study describes a woman with mild PKU who was able to deliver a healthy infant by maintaining her phenylalanine-restricted diet during pregnancy.
Phenyl ketonuria @@@@@
Classical phenylketonuria (PKU) is an inherited disorder where the enzyme phenylalanine hydroxylase is absent, preventing the conversion of phenylalanine to tyrosine. This causes phenylalanine to accumulate in the blood and be metabolized into alternative catabolites, including phenylpyruvic acid and phenylacetic acid conjugated with glutamine and excreted in urine, giving it a "mousy odor". Accumulation of phenylalanine can also impair serotonin and melanin formation. Clinical features include mental retardation, seizures, and eczema. Diagnosis involves measuring elevated plasma phenylalanine levels and testing urine for phenylpyruvate. Treatment
Phenylketonuria ( PKU) - Dr Padmesh
This document discusses phenylketonuria (PKU), a genetic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase. This enzyme is needed to break down the amino acid phenylalanine. Without it, phenylalanine builds up to high levels in the blood and brain, which can cause intellectual disability if not treated early. The document outlines the causes, symptoms, diagnosis through newborn screening, and lifelong treatment through a phenylalanine-restricted diet for PKU patients. It also discusses milder forms that do not require dietary treatment and the rare cases caused by a deficiency in the cofactor tetrahydrobiopterin.
Aminoaciduria phenylketonuria
Phenylketonuria is one of fthe inborn error of metabolism. Its characteristically error in amino acid metabolism. This causes aminoaciduria. Phenylalanine is an amino acid requied for protein synthesis as well as synthesis of tyrosine. Deficiency of the enzyme phenylalanine hyydroxylase triggers the accumulation of phenylalanine in the blood and subsequent conversion and transamination to ohenylpyruvate which is a phenylketone. This causes accumulation of phenylketones in urine with characteristicc mousy smell.
This slide discussess the causes and biochemistry of this error.
PKU-biochemical genetic disorder- 19.1.2023.ppt
Phenylketonuria (PKU) is an autosomal recessive genetic disorder caused by a deficiency of the enzyme phenylalanine hydroxylase, resulting in an inability to metabolize the essential amino acid phenylalanine. If left untreated, PKU can cause intellectual disabilities, seizures, and other neurological problems in affected individuals. Treatment involves restricting dietary phenylalanine through a specialized low-protein diet to control phenylalanine levels. Females with PKU must adhere to the diet prior to and during pregnancy to prevent complications in offspring from high phenylalanine passing through the placenta.
Aminoaciduria and organic aciduria in neurology
aminoaciduria and organic aciduria are considered as important disorder in the group of inborn error of metabolism.
Phenylketonuria (PKU)
Phenylketonuria (PKU) : is a genetic disorder that is characterized by an inability of the body to utilize the essential amino acid, phenylalanine.
Phenylketonuria
Phenylketonuria (PKU) is a genetic disorder caused by mutations in the PAH gene that result in deficient phenylalanine hydroxylase enzyme activity. This prevents the breakdown of the essential amino acid phenylalanine, causing it to accumulate to toxic levels and cause neurological damage if left untreated. Symptoms of PKU include intellectual disability, seizures, and behavioral issues. Treatment involves a lifelong low-phenylalanine diet to control blood phenylalanine levels, as well as enzyme replacement or gene therapies currently under investigation.
Phenylketonuria (pku)
PHENYLKETONURIA is due to hyperphenylalaninemia
Classic variant of PKU is due to the absence of phenylalanine hydroxylase.
keto.pptx
Phenylketonuria (PKU) is an inherited disorder that causes the body to be unable to break down an amino acid called phenylalanine. If left untreated, it can cause intellectual disabilities and other neurological problems. There are different types of PKU depending on severity. It is caused by mutations that impact the phenylalanine hydroxylase enzyme needed to metabolize phenylalanine. Symptoms usually appear between 3-6 months of age if untreated. Diagnosis involves newborn blood tests and managing PKU involves a lifelong low-phenylalanine diet to control symptoms and prevent complications.
Genetic mutations project
PKU is a genetic mutation where the body lacks the enzyme phenylalanine hydroxylase needed to break down the amino acid phenylalanine. When phenylalanine builds up in the blood, it damages the brain and nervous system, potentially causing intellectual disabilities, behavioral issues, and other health problems. It is treated through a lifelong low-phenylalanine diet to prevent toxic buildup. PKU affects approximately 1 in 10,000-15,000 newborns. It is diagnosed through newborn screening and managed through dietary control.
Phenyl ketonuria
INBORN ERRORS OF METABOLISM, PKU, PHENYLKETONURIA, BY: MR. DINABANDHU BARAD, MSC TUTOR, SUM NURSING COLLEGE, SIKSHA O ANUSANDHAN DEEMED TO BE UNIVERSITY, BHUBANESWAR, ODISHA
Phenylketonuria
Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine. A birth defect that causes an amino acid called phenylalanine to build up in the body.
Newborns should be screened for PKU.
Untreated phenylketonuria can lead to brain damage, intellectual disabilities, behavioural symptoms or seizures.
Treatment includes a strict diet with limited protein.
Phenylketonuria
This fill is represented has the WHAT IS PHENYLKETONURIA,DISCOVERY,NORMAL LEVEL IN BLOOD, HEREDITY,DEFECTS OF CHROMOSOME,CLASSESS OF PHENYLKETONURIA, SYMPTOMS, DIAGNOSIS, TREATMENT &etc...
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...College of pharmaceutical sciences
Decarboxylation is the reaction by which CO2 is removed from the COOH group of an amino acid as a result an amine is formed. The reaction is catalyzed by the enzyme decarboxylase, which requires pyridoxal-P (B6-PO4) as coenzyme. Tissues like liver, kidney, brain possess the enzyme decarboxylase and also by microorganisms of intestinal tract. The enzyme removes CO2 from COOH and converts the amino acid to corresponding amine.
Phenylalanine is an essential, aromatic amino acid. The need for phenylalanine becomes minimal, if adequate tyrosine is supplied in the food. This is called the sparing action of tyrosine on phenylalanine.
Tyrosine is an aromatic amino acid. It is synthesized from phenylalanine, and so is a non-essential amino acid. The need for phenylalanine becomes minimal, if adequate tyrosine is supplied in the food. This is called the sparing action of tyrosine on the phenylalanine.
Seven amino acids produce acetyl CoA or acetoacetate and therefore are categorized as ketogenic. Of these, isoleucine, threonine, and the aromatic amino acids (phenylalanine, tyrosine, and tryptophan) are converted to compounds that produce both glucose and acetyl CoA or acetoacetate. Leucine and lysine do not produce glucose; they produce acetyl CoA and acetoacetate.
The name phenylketonuria is coined due to the fact that the metabolite phenylpyruvate is a keto acid (C6H5CH2−CO−COO−) excreted in urine in high amounts.
Phenylalanine cannot be converted to tyrosine. So, phenylalanine accumulates. Phenylalanine level in blood is elevated.Phenylketonuria alex gandhi and athavan balendran
Phenylketonuria is a genetic disorder caused by a mutation in the PAH gene, which results in excessive levels of the amino acid phenylalanine. If left untreated, it can cause intellectual disabilities, stunted growth, eczema, small head size, and seizures. Treatment involves maintaining appropriate phenylalanine levels through diet control. It occurs in about 1 in 10,000 to 15,000 births and can be diagnosed via a blood test.
enfermedades innatas del metabolismo pku
enfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fe
Phenylketonuria
Phenylketonuria (PKU) is a rare genetic disorder caused by a mutation in the PAH gene that results in a deficiency of the enzyme phenylalanine hydroxylase. This enzyme is needed to break down the amino acid phenylalanine, which accumulates and causes neurological damage if left untreated. PKU is typically diagnosed via newborn screening and can be successfully managed through a lifelong low-phenylalanine diet and supplements to prevent intellectual disability and other serious issues. Untreated PKU leads to neurological problems, but early diagnosis and strict dietary control allows patients to live healthy lives.
Phenylketonuria ..
Phenylketonuria (PKU) is a rare genetic disorder caused by a mutation that prevents the body from breaking down phenylalanine, leading to its buildup in the blood and brain. PKU is treated through a low-protein diet and dietary supplements to control phenylalanine levels and prevent intellectual disabilities and other health issues. Left untreated, PKU can cause permanent brain damage and intellectual disabilities. Newborns are screened for PKU through a heel prick blood test to enable early treatment and management of the disorder.
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...PVI, PeerView Institute for Medical Education
Barbara K. Burton, MD, and Nicola Longo, MD, PhD, prepared useful practice aids pertaining to phenylketonuria for this CME activity titled "The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adults With PKU." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2sBC77b. CME credit will be available until June 13, 2019.Phenylketonuria PKU - Inborn error metabolism
The slides gives you a complete information on the inborn error metabolic disease Phenylketonuria (PKU) its cause, symptoms, mechanism and dietary management.
Lea el anlisis dado y d las respuestas a las preguntas .pdf
Lea el anlisis dado y d las respuestas a las preguntas: -
MS ALL DE LA CARNE: CAMBIO DEL COMPORTAMIENTO DEL CLIENTE EN ALIMENTOS
CONSUMO
Fue a mediados de 2014, y como fundador y director ejecutivo (CEO) de Beyond Meat, Ethan
Brown,
se desplaz por el feed de Twitter de la empresa, le complaci ver la secuencia de fotos que
presentaban a Beyond
Carne en una variedad de alimentos. Beyond Meat ahora se puede encontrar en platos desde
sopa de pollo con fideos hasta cremoso
pasta. Le hizo pensar en la cena de 2009 que haba comenzado todo: Brown haba estado
trabajando en el
compaa de celdas de combustible Ballard Power Systems Inc. (Ballard), y se qued perplejo al
notar que sus colegas
en una cena de conferencia eligi un bistec como plato principal, un alimento de alto consumo
energtico que pareca estar en desacuerdo con
Los esfuerzos de Ballard para convertir la energa de manera ms eficiente. Al ver este contraste
entre misin y comportamiento,
Brown se haba preguntado a s mismo: "Qu tan difcil puede ser cambiar lo que comes en la
cena?" Motivado por esto
pregunta, fund Beyond Meat en 2009 con la misin de crear soluciones para el mercado masivo
que
reemplazar la protena animal con protena vegetal.
La empresa haba enfrentado todos los desafos tpicos de una puesta en marcha, y Brown y sus
colegas saban que, en
adems de estos, su mayor desafo sera cambiar el comportamiento del cliente. La carne tuvo un
papel central en
La cultura y la sociedad de los EE. UU., desde barbacoas de verano y comidas festivas hasta
comidas para llevar, como perritos calientes en
juegos de bisbol y nuggets de pollo en los autoservicios. El nombre y el logotipo de "tenedor
imposible" de Beyond Meat
eran smbolos de la intencin de Brown de desafiar esto mediante la evolucin de la "carne" a un
nuevo nivel y la produccin de una alta
alternativa de carne de calidad (ver Anexo 1).
Suponiendo que se pudiera producir y comercializar una alternativa a la carne de manera
rentable, Beyond Meat tambin
necesitan hacer que su carne a base de plantas sea social y culturalmente apetecible. Esto
implicara cambiar la cena de EE. UU.
hbitosun ejercicio que requerira que Beyond Meat considerara cmo su producto se compara con
la carne animal en
trminos de su aspecto, sabor, sensacin, apariencia y contenido nutricional. Tambin implicara
considerar los mercados objetivo
y segmentos de clientes, as como decidir si utilizar argumentos ecolgicos y/o ticos en el
marketing.
Brown quera que Beyond Meat cambiara las reglas del juego en la industria crnica, al igual que
Silk, a base de soya y almendras.
haba cambiado la industria lctea. Envasar su leche de soya en un cartn estndar con tapa a dos
aguas haba permitido a Silk
superar las reticencias de los clientes alineando el producto con los productos lcteos
tradicionales. Seda haba sido capaz de
aumentar considerablemente su cuota de mercado mediante el uso de envases y colocacin de
productos que atraigan a los consumidores
buscando una alternativa muy sim.
The main disagreement between James Madison and Alexander Ha.pdf
The main disagreement between James Madison and Alexander Hamilton was whether the "general welfare" clause in the Constitution granted Congress broad spending powers or was limited only to those powers enumerated in the Constitution. Madison argued that the federal government's powers were strictly limited to those specifically listed, while Hamilton believed the clause granted Congress broad discretion to tax and spend for the general welfare.
More Related Content
Similar to Background Phenylketonuria is an inherited disease which re.pdf
Phenyl ketonuria @@@@@
Classical phenylketonuria (PKU) is an inherited disorder where the enzyme phenylalanine hydroxylase is absent, preventing the conversion of phenylalanine to tyrosine. This causes phenylalanine to accumulate in the blood and be metabolized into alternative catabolites, including phenylpyruvic acid and phenylacetic acid conjugated with glutamine and excreted in urine, giving it a "mousy odor". Accumulation of phenylalanine can also impair serotonin and melanin formation. Clinical features include mental retardation, seizures, and eczema. Diagnosis involves measuring elevated plasma phenylalanine levels and testing urine for phenylpyruvate. Treatment
Phenylketonuria ( PKU) - Dr Padmesh
This document discusses phenylketonuria (PKU), a genetic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase. This enzyme is needed to break down the amino acid phenylalanine. Without it, phenylalanine builds up to high levels in the blood and brain, which can cause intellectual disability if not treated early. The document outlines the causes, symptoms, diagnosis through newborn screening, and lifelong treatment through a phenylalanine-restricted diet for PKU patients. It also discusses milder forms that do not require dietary treatment and the rare cases caused by a deficiency in the cofactor tetrahydrobiopterin.
Aminoaciduria phenylketonuria
Phenylketonuria is one of fthe inborn error of metabolism. Its characteristically error in amino acid metabolism. This causes aminoaciduria. Phenylalanine is an amino acid requied for protein synthesis as well as synthesis of tyrosine. Deficiency of the enzyme phenylalanine hyydroxylase triggers the accumulation of phenylalanine in the blood and subsequent conversion and transamination to ohenylpyruvate which is a phenylketone. This causes accumulation of phenylketones in urine with characteristicc mousy smell.
This slide discussess the causes and biochemistry of this error.
PKU-biochemical genetic disorder- 19.1.2023.ppt
Phenylketonuria (PKU) is an autosomal recessive genetic disorder caused by a deficiency of the enzyme phenylalanine hydroxylase, resulting in an inability to metabolize the essential amino acid phenylalanine. If left untreated, PKU can cause intellectual disabilities, seizures, and other neurological problems in affected individuals. Treatment involves restricting dietary phenylalanine through a specialized low-protein diet to control phenylalanine levels. Females with PKU must adhere to the diet prior to and during pregnancy to prevent complications in offspring from high phenylalanine passing through the placenta.
Aminoaciduria and organic aciduria in neurology
aminoaciduria and organic aciduria are considered as important disorder in the group of inborn error of metabolism.
Phenylketonuria (PKU)
Phenylketonuria (PKU) : is a genetic disorder that is characterized by an inability of the body to utilize the essential amino acid, phenylalanine.
Phenylketonuria
Phenylketonuria (PKU) is a genetic disorder caused by mutations in the PAH gene that result in deficient phenylalanine hydroxylase enzyme activity. This prevents the breakdown of the essential amino acid phenylalanine, causing it to accumulate to toxic levels and cause neurological damage if left untreated. Symptoms of PKU include intellectual disability, seizures, and behavioral issues. Treatment involves a lifelong low-phenylalanine diet to control blood phenylalanine levels, as well as enzyme replacement or gene therapies currently under investigation.
Phenylketonuria (pku)
PHENYLKETONURIA is due to hyperphenylalaninemia
Classic variant of PKU is due to the absence of phenylalanine hydroxylase.
keto.pptx
Phenylketonuria (PKU) is an inherited disorder that causes the body to be unable to break down an amino acid called phenylalanine. If left untreated, it can cause intellectual disabilities and other neurological problems. There are different types of PKU depending on severity. It is caused by mutations that impact the phenylalanine hydroxylase enzyme needed to metabolize phenylalanine. Symptoms usually appear between 3-6 months of age if untreated. Diagnosis involves newborn blood tests and managing PKU involves a lifelong low-phenylalanine diet to control symptoms and prevent complications.
Genetic mutations project
PKU is a genetic mutation where the body lacks the enzyme phenylalanine hydroxylase needed to break down the amino acid phenylalanine. When phenylalanine builds up in the blood, it damages the brain and nervous system, potentially causing intellectual disabilities, behavioral issues, and other health problems. It is treated through a lifelong low-phenylalanine diet to prevent toxic buildup. PKU affects approximately 1 in 10,000-15,000 newborns. It is diagnosed through newborn screening and managed through dietary control.
Phenyl ketonuria
INBORN ERRORS OF METABOLISM, PKU, PHENYLKETONURIA, BY: MR. DINABANDHU BARAD, MSC TUTOR, SUM NURSING COLLEGE, SIKSHA O ANUSANDHAN DEEMED TO BE UNIVERSITY, BHUBANESWAR, ODISHA
Phenylketonuria
Phenylketonuria (PKU) is an inborn error of metabolism that results in decreased metabolism of the amino acid phenylalanine. A birth defect that causes an amino acid called phenylalanine to build up in the body.
Newborns should be screened for PKU.
Untreated phenylketonuria can lead to brain damage, intellectual disabilities, behavioural symptoms or seizures.
Treatment includes a strict diet with limited protein.
Phenylketonuria
This fill is represented has the WHAT IS PHENYLKETONURIA,DISCOVERY,NORMAL LEVEL IN BLOOD, HEREDITY,DEFECTS OF CHROMOSOME,CLASSESS OF PHENYLKETONURIA, SYMPTOMS, DIAGNOSIS, TREATMENT &etc...
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...College of pharmaceutical sciences
Decarboxylation is the reaction by which CO2 is removed from the COOH group of an amino acid as a result an amine is formed. The reaction is catalyzed by the enzyme decarboxylase, which requires pyridoxal-P (B6-PO4) as coenzyme. Tissues like liver, kidney, brain possess the enzyme decarboxylase and also by microorganisms of intestinal tract. The enzyme removes CO2 from COOH and converts the amino acid to corresponding amine.
Phenylalanine is an essential, aromatic amino acid. The need for phenylalanine becomes minimal, if adequate tyrosine is supplied in the food. This is called the sparing action of tyrosine on phenylalanine.
Tyrosine is an aromatic amino acid. It is synthesized from phenylalanine, and so is a non-essential amino acid. The need for phenylalanine becomes minimal, if adequate tyrosine is supplied in the food. This is called the sparing action of tyrosine on the phenylalanine.
Seven amino acids produce acetyl CoA or acetoacetate and therefore are categorized as ketogenic. Of these, isoleucine, threonine, and the aromatic amino acids (phenylalanine, tyrosine, and tryptophan) are converted to compounds that produce both glucose and acetyl CoA or acetoacetate. Leucine and lysine do not produce glucose; they produce acetyl CoA and acetoacetate.
The name phenylketonuria is coined due to the fact that the metabolite phenylpyruvate is a keto acid (C6H5CH2−CO−COO−) excreted in urine in high amounts.
Phenylalanine cannot be converted to tyrosine. So, phenylalanine accumulates. Phenylalanine level in blood is elevated.Phenylketonuria alex gandhi and athavan balendran
Phenylketonuria is a genetic disorder caused by a mutation in the PAH gene, which results in excessive levels of the amino acid phenylalanine. If left untreated, it can cause intellectual disabilities, stunted growth, eczema, small head size, and seizures. Treatment involves maintaining appropriate phenylalanine levels through diet control. It occurs in about 1 in 10,000 to 15,000 births and can be diagnosed via a blood test.
enfermedades innatas del metabolismo pku
enfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fenilcetonuriaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaenfermedades innata del metabolismo- fe
Phenylketonuria
Phenylketonuria (PKU) is a rare genetic disorder caused by a mutation in the PAH gene that results in a deficiency of the enzyme phenylalanine hydroxylase. This enzyme is needed to break down the amino acid phenylalanine, which accumulates and causes neurological damage if left untreated. PKU is typically diagnosed via newborn screening and can be successfully managed through a lifelong low-phenylalanine diet and supplements to prevent intellectual disability and other serious issues. Untreated PKU leads to neurological problems, but early diagnosis and strict dietary control allows patients to live healthy lives.
Phenylketonuria ..
Phenylketonuria (PKU) is a rare genetic disorder caused by a mutation that prevents the body from breaking down phenylalanine, leading to its buildup in the blood and brain. PKU is treated through a low-protein diet and dietary supplements to control phenylalanine levels and prevent intellectual disabilities and other health issues. Left untreated, PKU can cause permanent brain damage and intellectual disabilities. Newborns are screened for PKU through a heel prick blood test to enable early treatment and management of the disorder.
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...PVI, PeerView Institute for Medical Education
Barbara K. Burton, MD, and Nicola Longo, MD, PhD, prepared useful practice aids pertaining to phenylketonuria for this CME activity titled "The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adults With PKU." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2sBC77b. CME credit will be available until June 13, 2019.Phenylketonuria PKU - Inborn error metabolism
The slides gives you a complete information on the inborn error metabolic disease Phenylketonuria (PKU) its cause, symptoms, mechanism and dietary management.
Similar to Background Phenylketonuria is an inherited disease which re.pdf (20)
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...
Catabolism of phenylalanine and tyrosine and their metabolic disorders by BNP...
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...
The Evolving Role of Current and Novel Therapies in Improving Outcomes in Adu...
More from aisprayers
Lea el anlisis dado y d las respuestas a las preguntas .pdf
Lea el anlisis dado y d las respuestas a las preguntas: -
MS ALL DE LA CARNE: CAMBIO DEL COMPORTAMIENTO DEL CLIENTE EN ALIMENTOS
CONSUMO
Fue a mediados de 2014, y como fundador y director ejecutivo (CEO) de Beyond Meat, Ethan
Brown,
se desplaz por el feed de Twitter de la empresa, le complaci ver la secuencia de fotos que
presentaban a Beyond
Carne en una variedad de alimentos. Beyond Meat ahora se puede encontrar en platos desde
sopa de pollo con fideos hasta cremoso
pasta. Le hizo pensar en la cena de 2009 que haba comenzado todo: Brown haba estado
trabajando en el
compaa de celdas de combustible Ballard Power Systems Inc. (Ballard), y se qued perplejo al
notar que sus colegas
en una cena de conferencia eligi un bistec como plato principal, un alimento de alto consumo
energtico que pareca estar en desacuerdo con
Los esfuerzos de Ballard para convertir la energa de manera ms eficiente. Al ver este contraste
entre misin y comportamiento,
Brown se haba preguntado a s mismo: "Qu tan difcil puede ser cambiar lo que comes en la
cena?" Motivado por esto
pregunta, fund Beyond Meat en 2009 con la misin de crear soluciones para el mercado masivo
que
reemplazar la protena animal con protena vegetal.
La empresa haba enfrentado todos los desafos tpicos de una puesta en marcha, y Brown y sus
colegas saban que, en
adems de estos, su mayor desafo sera cambiar el comportamiento del cliente. La carne tuvo un
papel central en
La cultura y la sociedad de los EE. UU., desde barbacoas de verano y comidas festivas hasta
comidas para llevar, como perritos calientes en
juegos de bisbol y nuggets de pollo en los autoservicios. El nombre y el logotipo de "tenedor
imposible" de Beyond Meat
eran smbolos de la intencin de Brown de desafiar esto mediante la evolucin de la "carne" a un
nuevo nivel y la produccin de una alta
alternativa de carne de calidad (ver Anexo 1).
Suponiendo que se pudiera producir y comercializar una alternativa a la carne de manera
rentable, Beyond Meat tambin
necesitan hacer que su carne a base de plantas sea social y culturalmente apetecible. Esto
implicara cambiar la cena de EE. UU.
hbitosun ejercicio que requerira que Beyond Meat considerara cmo su producto se compara con
la carne animal en
trminos de su aspecto, sabor, sensacin, apariencia y contenido nutricional. Tambin implicara
considerar los mercados objetivo
y segmentos de clientes, as como decidir si utilizar argumentos ecolgicos y/o ticos en el
marketing.
Brown quera que Beyond Meat cambiara las reglas del juego en la industria crnica, al igual que
Silk, a base de soya y almendras.
haba cambiado la industria lctea. Envasar su leche de soya en un cartn estndar con tapa a dos
aguas haba permitido a Silk
superar las reticencias de los clientes alineando el producto con los productos lcteos
tradicionales. Seda haba sido capaz de
aumentar considerablemente su cuota de mercado mediante el uso de envases y colocacin de
productos que atraigan a los consumidores
buscando una alternativa muy sim.
The main disagreement between James Madison and Alexander Ha.pdf
The main disagreement between James Madison and Alexander Hamilton was whether the "general welfare" clause in the Constitution granted Congress broad spending powers or was limited only to those powers enumerated in the Constitution. Madison argued that the federal government's powers were strictly limited to those specifically listed, while Hamilton believed the clause granted Congress broad discretion to tax and spend for the general welfare.
Sabah proje ekibi toplants ilgin olacana sz verdi Pazarla.pdf
Sabah proje ekibi toplants ilgin olacana sz verdi. Pazarlama departman temsilcileri Jane Pauley ile
finans departman Juan Castro arasndaki gerilim birka haftadr --- aslnda proje ekibi
oluturulduundan beri artyor. Mkemmel rnler iin zel Projeler Blm bakan Sammy Bonsu, Project
Excellence'n proje yneticisi olarak Jane ve Juan'n ayn fikirde olmadklarnn farkndayd, ancak
(Sammy) zamanla birbirlerinin bak asn takdir edeceklerini anlad. ve ibirlii yapmaya balayn. imdiye
kadar, ne yazk ki, bu olmad. Aslnda, Sammy Bonsu'nun dier ekip yesinin davranlar, ballk veya
ibirlii eksiklii veya genel kalitesiz performansla ilgili olarak birinden veya dierinden ikayet almad bir
gn bile gemiyor gibi grnyor.
Project Excellence yaklak 4 aydr alyor. Proje Mkemmellii iin son tarih, Denise Robinson (Mkemmel
rnler Bakan) tarafndan 1 Ocak 2021 olarak belirlendi. Sammy Bonsu, ilevler aras ekiplerle birlikte
4 projeden daha sorumluydu. Yllar boyunca, Excellent Products, pazara hzla yeni rnler getirmesi
ve mterileri memnun etmesiyle tannyordu. Sammy, irketin 20 yllk varlnn ayrlmaz bir parasyd.
Aslnda, Denise ve Sammy niversitede snf arkadalaryd. Birbirlerine her zaman byk bir gven ve
sayg duyarlar. Ancak, Jane Pauley ve Juan Castro arasnda farkl bir hikaye vard. Jane ve Juan,
Excellent Products'a be yl nce katld. Her biri son derece rekabeti ve iinden byk gurur duyuyor.
(Jane ve Juan) farkl grlere sahip olsalar da her biri irkete sadktr.
Ekip, sabah 9:00'da dzenli bir aylk proje durum toplants iin toplanrken, Sammy Bonsu proje
grevleri, ekip yelerinin yaad sorunlar ve projenin bugne kadarki performansna ilikin
deerlendirmeleri hakknda bir gncelleme ile balar. Sammy toplantya fazla dalmadan nce Jane
araya girerek, Sammy, nmzdeki 10 gn boyunca mterileri ziyaret etmek iin ehir dnda olacam, bu
yzden nmzdeki iki Cuma gn de durum toplantlarna katlamayacam.
Juan herkesin duyabilecei kadar yksek sesle, "yle grnyor," diye mrldand.
Jane etrafnda dnyor. "Buralarda baka bir iim var, biliyorsun ve bu da sat yapmay ieriyor. Her eyi
brakp bu toplantlara gelmeniz uygun olabilir ama bazlarmzn baka sorumluluklar var.
Juan karlk veriyor, "imdiye kadar toplantlarn yarsn karmann bahanesi buydu. Sadece meraktan,
diye devam etti alayc bir ekilde, daha ka kii havuz kenarnda taklrken ehir dndan gelen kk
insanlarla umay dnyor?
Jane parlak krmzya dner. "Sana katlanmak zorunda deilim. Fasulye sayalarnn bu iin nasl altna
veya kimin deer saladna dair hibir fikriniz yok. Her kuruunu analiz etmekle o kadar megulsn ki kalc
gz yorgunluun var!
Juan, "Satta srekli olarak siz kovboylarn arkasnda durmak zorunda kalmasaydm belki biraz dikkat
edebilirdim," diye kar kyor Juan. "Yemin ederim ki, bu bizi mahvedecek olsa bile, aylk rakamlarnz
yapmanza izin verseydi rnlerimizi ele verirdiniz!"
Jane ve Juan arasndaki tartmalar tam lekli bir dmanla dntnde ve kontrolden kma tehdidinde
bulunurken Sammy Bonsu hayretle arkasna yaslanr. Dier ekip yeleri, tepkisi iin Sammy'ye bakar.
Mhendislikten Anil Patel'in yznde komik bir .
public class CustomerList private ListltCustomergt .pdf
public class CustomerList
{
private List<Customer> customers;
public delegate void ChangeHandler(CustomerList customers);
public event ChangeHandler ChangedList;
public CustomerList()
{
customers = new List<Customer>();
}
public void Add(Customer c)
{
customers.Add(c);
}
public static CustomerList operator + (CustomerList customers, Customer c)
{
customers.Add(c);
return customers;
}
}
(Refer to code example 13-2) Which of the following statements adds a Customer object named
newCustomer to a CustomerList object named customers?
customers = customers + newCustomer;
A and B
customers.Add(newCustomer);
All of the above
customers += newCustomer;.
Ten Hellos Write a program to print ten Hellos They s.pdf
Ten Hellos! Write a program to print ten "Hello!"s. They should look as follows (see next line) and
please use a for() loop for i=4; i<=10.
1st Hello! 2nd Hello! 3rd Hello! 4th Hello! 5th Hello! 6th Hello! 7th Hello! 8th Hello! 9th Hello 10th
Hello!.
The hypothesis HO 12 Ha 1lt2 is an example of upper.pdf
The hypothesis, HO: 1=2, Ha: 1<2, is an example of: upper (right) tailed test. lower (left) tailed
test. paired test. two tailed test..
Select all of the characteristics of SEXUAL Reproduction A .pdf
Select all of the characteristics of SEXUAL Reproduction.
A
Organisms have to search for a mate, which can take a long time.
B
Offspring inherit half of their DNA from each parent.
C
Organisms can reproduce a large number of offspring quickly.
D
Organisms can reproduce without a mate.
E
Organisms have to grow and develop until they are mature enough to produce sex cells.
F
Offspring are genetically identical to the single parent..
The Capital Asset Pricing Model CAPM is a financial model .pdf
The Capital Asset Pricing Model (CAPM) is a financial model that assumes returns on a portfolio
are normally distributed. Suppose a portfolio has an average annual return of 12.8% (i.e., an
average gain of 12.8%) with a standard deviation of 35%. A return of 0% means the value of the
portfolio doesn't change, a negative return means that the portfolio loses money, and a positive
return means that the portfolio gains money. (Round your answers to two decimal places.).
Read Knowledge attitude and practice in relation to cathet.pdf
Read: Knowledge, attitude and practice in relation to catheter-associated urinary tract infection
prevention: A cross sectional study
Cited: Mong, I., Ramoo, V., Ponnampalavanar, S., Chong, M. C., & Wan Nawawi, W. N. F. (2022).
Knowledge, attitude and practice in relation to catheter-associated urinary tract infection (CAUTI)
prevention: A cross-sectional study. Journal of clinical nursing, 31(1-2), 209219.
https://doi.org/10.1111/jocn.15899
Answer:
1. Is the framework presented with clarity?. Is the framework linked to the research purpose? If no
theoretical framework identified, should there be? What framework might have been or could have
been used?
2. Identify the specific design of the study. Is the design appropriate for the study? Does the
sample fit with the research design and is the size sufficient? Was a data collection instrument
needed/used? How were data collected? Were reliability and validity accounted for?
3. Did the method used to gain study subjects coordinate with the study methodology? Was it
accurately and completely described?.
Los registros de la sociedad muestran los siguientes saldos .pdf
Los registros de la sociedad muestran los siguientes saldos de capital a la fecha del retiro de
Hopkins: M. Hammel, $80,000; D. Hopkins, $210,000; y P.Houghton, $100,000. Los tres socios
comparten ingresos y prdidas por igual. El 31 de diciembre, Hopkins se retira y acepta recibir
$210 000 en efectivo para liquidar su saldo de capital. Prepare el asiento de diario del 31 de
diciembre para la sociedad..
Mini Caso Competencia en la Industria Aeronutica Durante m.pdf
Mini Caso: Competencia en la Industria Aeronutica
Durante muchos aos, la industria de las aerolneas estuvo muy regulada, lo que result en que, por
definicin, la mayora de las aerolneas actuaran como las dems. Sin embargo, las similitudes entre
las grandes compaas areas se mantuvieron despus de que la industria fuera parcialmente
desregulada hace ms de 30 aos. Estas similitudes, en servicios, rutas y rendimiento, han
persistido hasta el presente. Por ejemplo, las aerolneas a menudo ofrecen un nuevo servicio (p.
ej., disponibilidad de Wi-Fi en los vuelos), pero estos servicios se imitan fcilmente, por lo que
cualquier diferenciacin en las ofertas es solo temporal. En los ltimos tiempos, se ha producido una
consolidacin en las industrias de las aerolneas europeas y estadounidenses. En particular, el bajo
rendimiento llev a US Air y America West a fusionarse. Adems, por las mismas razones,
Northwest Airlines y Delta Airlines se fusionaron. Asimismo, United Airlines y Continental se
fusionaron para crear la aerolnea ms grande de la industria. Ms recientemente, se aprob la fusin
de American Airlines y US Air. Gran parte de la consolidacin se aprob porque varias de las
aerolneas se declararon en quiebra (por ejemplo, Continental y United se declararon en quiebra
antes de su fusin). Todas estas fusiones, sin embargo, no han creado servicios (o precios)
altamente diferenciados. Todas las aerolneas brindan en gran medida el mismo tipo de servicios,
y los precios no difieren mucho entre las grandes aerolneas de "servicio completo". De hecho,
parece que la competencia principal est en tratar de cometer menos errores. De hecho, las
estadsticas de la industria que reportan cuentas positivas, anuncian resultados tales como una
reduccin en el equipaje perdido, menos cancelaciones de vuelos y menos demoras. Lo que esto
sugiere es que es probable que todas estas reas an representen reas problemticas importantes.
Parece bastante malo cuando la declaracin ms positiva que uno puede hacer es que se han
perdido menos bolsas en los ltimos tiempos. Aunque las ganancias han aumentado ms
recientemente, esto se debe principalmente a los menores costos de combustible y una mayor
demanda debido a que la economa est creciendo, algo que no est controlado por quienes estn a
cargo de la estrategia. Obviamente, existen diferencias entre las aerolneas a lo largo del tiempo.
United, la aerolnea ms grande, se fusion con Continental para crear ms eficiencia financiera y
ofrecer mayores opciones de viaje a los clientes. Sin embargo, ha tenido problemas significativos
para que la fusin de los dos sistemas funcione de manera efectiva. De hecho, anunci una gran
prdida neta para 2012 debido a sus problemas. Por ejemplo, en noviembre de 2012, una falla en
la computadora (problema de software) provoc el retraso de 250 vuelos de United en todo el
mundo durante casi dos horas. Su sistema de reservas fall dos veces durante 2012, lo que provoc
el cierre de su sitio web, lo que dej varados a .
q1 Finalaccepting states q2 Transitions function No.pdf
q1) Final/accepting states?
q2) Transitions function?
Note that 1=20 Example of how to enter the Turing machine: Final/accepting states: Transition
function: d(q,a)=(q1,a,R)d(q,#)=(q2,#,L)d(q1,a)=(q,a,R) Important notes: - the Turing machine
should not leave the bounds of the input word (in particular, blank symbols must be left
unchanged) - the Turing machine should be deterministic - the Turing machine can have at most
23 states - the starting state is always - the blank symbol is - the tape alphabet consists of single
characters (letters or digits).
Parte 2 Verifique su comprensin Para cada individuo su.pdf
Parte 2 - Verifique su comprensin - Para cada individuo, sugiera un activo financiero de la lista
provista que sea apropiado para su circunstancia y explique su razonamiento.
cuenta corriente/efectivo cuenta de ahorro bienes races bitcoin certificados de depsito bonos
acciones (acciones).
Opcin mltiple 1 _________ se refiere a la confiscacin de.pdf
Opcin mltiple 1. _________ se refiere a la confiscacin de propiedad extranjera por parte de los
gobiernos anfitriones.a. Expatriacinb. Expropiacin c. Extraterritorialidadd. Ninguna de las
anteriores
2. En qu etapa del ciclo de vida del producto las empresas comienzan a producir en el extranjero?
a. Primerob. segundoc. tercero Cuatro
3. En trminos de mentalidad ejecutiva, las empresas ___________ son las ms propensas a
otorgar una autonoma considerable a las subsidiarias locales.a. policntrico b. Etnocntrico.
Geocntrico. centocntrico
4. Las empresas multinacionales tienen ms poder de negociacin, en relacin con los gobiernos
anfitriones, cuando pueden ofrecer lo siguiente al pas anfitrin: a. inversiones de capital b.
desarrollos de infraestructurac. trabajosd. Todas las anteriores e. Ninguna de las anteriores
5. Las empresas multinacionales encontrarn que un pas anfitrin es un destino menos atractivo
cuando . . .a. Las ganancias de la empresa no son fcilmente repatriadas b. El gobierno es
establec. Los tipos de cambio entre el pas de origen y el anfitrin no fluctan. Ninguna de las
anteriores
6. Es posible que los pases en desarrollo no puedan proteger su medio ambiente de los efectos
de la industrializacin, por dainos que sean, porque a. No les interesan las consecuencias
perjudiciales. b. Valorarn ms el aumento del empleo que la salud y la seguridad de los
ciudadanos. .c.No pueden permitirse las tecnologas necesarias para fabricar de una manera ms
ecolgica. re. Ninguna de las anteriores.
7. Las instituciones que promueven la conducta tica han incluido todas las siguientes excepto a.
La OIT (Organizacin Internacional del Trabajo) b. La OCDE (Organizacin para la Cooperacin y el
Desarrollo Econmicos) c. La CCI (Cmara de Comercio Internacional) d. El FMI (Organizacin
Internacional del Trabajo) Fondo Monetario)
8. Cul de las siguientes afirmaciones describe con mayor precisin la relacin que una empresa
debe tener con sus partes interesadas? a. Los clientes exigen bienes de calidad a un precio justo
y, a cambio, se espera que no demanden a la empresa si algo sale mal. b. capital de los
accionistas y, a cambio, proporcionar rendimientos saludables. c. Las partes interesadas brindan
incentivos a las empresas y, a cambio, las empresas contribuyen a todos los grupos de partes
interesadas. d. Las empresas valoran a todos los grupos de partes interesadas por igual en todo
momento.
9. Como uno de los grupos de partes interesadas de una CMN, los gobiernos anfitriones esperan
todo lo siguiente, excepto a. Mercanca gratis b. Mayor empleo para los locales c. Pago de
impuestos d. Respeto por las costumbres y la cultura locales
10. El debate sobre el libre comercio puede caracterizarse por la preocupacin por a.la creacin de
puestos de trabajo a largo plazo pero con bolsas de desempleo a corto plazo b.la creacin de
puestos de trabajo a corto plazo pero con bolsas de desempleo a largo plazo, se crea ms
comercio entre los bloques comerciales regionales que dentro d.
Genomic imprinting is generally due to the addition of methy.pdf
Genomic imprinting is generally due to the addition of methyl (CH3) groups to C nucleotides and
chemical histone changes to silence a given gene. If this depends on the sex of the parent who
transmits the gene, which of the following statements must be true? Methylation must be
reversible in ovarian and testicular cells. The imprints are transmitted only to gamete-producing
cells. Genes required for early development stages must not be imprinted. Methylation of this kind
must occur more in males than in females..
Integumentary muscles Extrinsic Integumentary muscles 1 Pl.pdf
Integumentary muscles
Extrinsic Integumentary muscles:
1. Platysma - derived from the _________
2. Cutaneous trunci - derived from _______ and _______
3. Sphincter coli in birds - derived from the ________
4. Costocutaneous muscles in snakes - ________
Electric Organs:
5. Specialized blocks of mm, derived from ______ mm or ____
produce a jolt of voltage.
Airplanes arrive to JFK according to a Poisson process The .pdf
Airplanes arrive to JFK according to a Poisson process. The average rate of their arrival is 45 per
hour. What is the probabilty that the time between the third and fourth arrivals is less than 2
minutes?.
Android question What is the effect of each of the followin.pdf
Android question:
What is the effect of each of the following on an Android activity:
1. not implementing the onSaveInstanceState() callback
2. implementing the onSaveInstanceState() callback but not calling the
super.onSaveInstanceState() method
3. implementing the onSaveInstanceState() callback and calling the super.onSaveInstanceState()
method.
Let X1X2Xn be iid random samples from Pareto1 a .pdf
Let X1,X2,,Xn be i.i.d. random samples from Pareto(,1). (a) Derive the Maximum Likelihood
Estimator of . Denote the MLE as ^MLE. (b) Let I() be the Fisher Information of based on 1
random variable. Find I()..
Exercise 4 Try to solve On January 1 2020 Kuwait Finance.pdf
Exercise 4 (Try to solve) On January 1, 2020, Kuwait Finance House (KFH) and Kuwait
International (KIB) bank entered into three years Mudarabah contract with Kuwait Real Estate
Company (KRC) with capital contributions of KD500,000 and KD300,000, respectively. The
agreed profitsharing ratio between KFH,ADIB, and KRC is 2:1:2, respectively. The profit and
losses from the contract are as follows: Required For each year: a) Determine the profit or losses
attributable to KFH, KIB, and KRC from the contract b) Determine the capital amount recovered by
KFH and KIB c) Prepare the appropriate accounting entries at KIB.
More from aisprayers (20)
Lea el anlisis dado y d las respuestas a las preguntas .pdf
Lea el anlisis dado y d las respuestas a las preguntas .pdf
The main disagreement between James Madison and Alexander Ha.pdf
The main disagreement between James Madison and Alexander Ha.pdf
Sabah proje ekibi toplants ilgin olacana sz verdi Pazarla.pdf
Sabah proje ekibi toplants ilgin olacana sz verdi Pazarla.pdf
public class CustomerList private ListltCustomergt .pdf
public class CustomerList private ListltCustomergt .pdf
Ten Hellos Write a program to print ten Hellos They s.pdf
Ten Hellos Write a program to print ten Hellos They s.pdf
The hypothesis HO 12 Ha 1lt2 is an example of upper.pdf
The hypothesis HO 12 Ha 1lt2 is an example of upper.pdf
Select all of the characteristics of SEXUAL Reproduction A .pdf
Select all of the characteristics of SEXUAL Reproduction A .pdf
The Capital Asset Pricing Model CAPM is a financial model .pdf
The Capital Asset Pricing Model CAPM is a financial model .pdf
Read Knowledge attitude and practice in relation to cathet.pdf
Read Knowledge attitude and practice in relation to cathet.pdf
Los registros de la sociedad muestran los siguientes saldos .pdf
Los registros de la sociedad muestran los siguientes saldos .pdf
Mini Caso Competencia en la Industria Aeronutica Durante m.pdf
Mini Caso Competencia en la Industria Aeronutica Durante m.pdf
q1 Finalaccepting states q2 Transitions function No.pdf
q1 Finalaccepting states q2 Transitions function No.pdf
Parte 2 Verifique su comprensin Para cada individuo su.pdf
Parte 2 Verifique su comprensin Para cada individuo su.pdf
Opcin mltiple 1 _________ se refiere a la confiscacin de.pdf
Opcin mltiple 1 _________ se refiere a la confiscacin de.pdf
Genomic imprinting is generally due to the addition of methy.pdf
Genomic imprinting is generally due to the addition of methy.pdf
Integumentary muscles Extrinsic Integumentary muscles 1 Pl.pdf
Integumentary muscles Extrinsic Integumentary muscles 1 Pl.pdf
Airplanes arrive to JFK according to a Poisson process The .pdf
Airplanes arrive to JFK according to a Poisson process The .pdf
Android question What is the effect of each of the followin.pdf
Android question What is the effect of each of the followin.pdf
Let X1X2Xn be iid random samples from Pareto1 a .pdf
Let X1X2Xn be iid random samples from Pareto1 a .pdf
Exercise 4 Try to solve On January 1 2020 Kuwait Finance.pdf
Exercise 4 Try to solve On January 1 2020 Kuwait Finance.pdf
Recently uploaded
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
PCOS corelations and management through Ayurveda.
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
Advanced Java[Extra Concepts, Not Difficult].docx
This is part 2 of my Java Learning Journey. This contains Hashing, ArrayList, LinkedList, Date and Time Classes, Calendar Class and more.
The Diamonds of 2023-2024 in the IGRA collection
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
Assessment and Planning in Educational technology.pptx
In an education system, it is understood that assessment is only for the students, but on the other hand, the Assessment of teachers is also an important aspect of the education system that ensures teachers are providing high-quality instruction to students. The assessment process can be used to provide feedback and support for professional development, to inform decisions about teacher retention or promotion, or to evaluate teacher effectiveness for accountability purposes.
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective UpskillingExcellence Foundation for South Sudan
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.Natural birth techniques - Mrs.Akanksha Trivedi Rama University
Natural birth techniques - Mrs.Akanksha Trivedi Rama UniversityAkanksha trivedi rama nursing college kanpur.
Natural birth techniques are various type such as/ water birth , alexender method, hypnosis, bradley method, lamaze method etcA Survey of Techniques for Maximizing LLM Performance.pptx
A Survey of Techniques for Maximizing LLM Performance
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar KanvariaDRUGS AND ITS classification slide share
Any substance (other than food) that is used to prevent, diagnose, treat, or relieve symptoms of a
disease or abnormal condition
CACJapan - GROUP Presentation 1- Wk 4.pdf
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)Academy of Science of South Africa
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
How to Add Chatter in the odoo 17 ERP Module
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Recently uploaded (20)
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Liberal Approach to the Study of Indian Politics.pdf
Liberal Approach to the Study of Indian Politics.pdf
Assessment and Planning in Educational technology.pptx
Assessment and Planning in Educational technology.pptx
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Your Skill Boost Masterclass: Strategies for Effective Upskilling
Natural birth techniques - Mrs.Akanksha Trivedi Rama University
Natural birth techniques - Mrs.Akanksha Trivedi Rama University
A Survey of Techniques for Maximizing LLM Performance.pptx
A Survey of Techniques for Maximizing LLM Performance.pptx
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...
South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
বাংলাদেশ অর্থনৈতিক সমীক্ষা (Economic Review) ২০২৪ UJS App.pdf
Background Phenylketonuria is an inherited disease which re.pdf
- 1. Background: Phenylketonuria is an inherited disease which results from the lack of the enzyme phenylalanine hydroxylase (PAH). The PAH enzyme catalyzes the first step in the degradation of phenylalanine, as shown in Figure 30.1. In the phenylketonuric patient, phenylalanine accumulates which is eventually transaminated to phenylpyruvate, a phenylketone compound. Excess phenylpyruvate accumulates in the blood and urine and has the effect of causing mental retardation if untreated. Screening programs identify PKU babies at birth, and treatment consists of a low phenylalanine diet until maturation of the brain is completed. The structure and biochemical properties of the PAH enzyme have been well-studied.The gene for PAH has been isolated and has been localized to chromosome 12. The PAH enzyme is a protein 451 amino acids in length with a molecular weight of 51,900 daltons. More than 60 different mutant genes giving rise to nonfunctional PAH proteins have been identified in PKU patients. Question:Kinetic data in which PAH activity is compared with and without preincubation with phenylalanine is shown in Figure 30.3. Give a structural basis for the interpretation of these data. Figure 30.1. Phenylalanine and tyrosine meravurior. an essential cofactor for phenylalanine hydroxylase. 95Figure 30.1. Phenylalanine and tyrosmio ..... an essential cofactor for phenylalanine hydroxylase. 95