Results of a calcium hydroxylapatitie (Radiesse) study performed on 27 patients with moderate to severe atrophic acne scarring for a period of 12 months. The results show a favorable and possible cheap alternative to laser resurfacing. A comparative HA study (hyaluronic acid) with 13 patients showed this product was of little therapeutic benefit.
This paper by Dr. Patrick Treacy Medical Director Ailesbury Clinics Ltd. sought to establish the efficacy and safety profile the dermal filler, calcium hydroxylapatite filler in the treatment of atrophic acne scars. Forty two subjects with differing degrees of atrophic acne scars were treated with this filler over an eighteen month period and the results are published below
Microblading is a semi permanent tattoo technique which involves the use of needles to give you thick luscious eye brows.Each stroke is created by hand by a trained expert to enhance and reshape the brows.A handheld tool is used instead of a tattoo machine which deposits pigment in the superficial layers of the skin that's why it lightens quickly.Initially your eyebrows might look quite dark but gradually matches the shade which goes with your skin.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing microblading in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
This document provides information about mesotherapy, including its history, indications, contraindications, drugs used, and complications. Some key points:
- Mesotherapy involves injecting small doses of medications into the mesoderm layer of skin to treat dermatological or internal lesions.
- It was first suggested by Dr. Michel Pistor in 1958 as a treatment between allopathic and homeopathic therapies.
- Common indications include aesthetic treatments like lipolysis and cellulite reduction, as well as pain management.
- Phosphatidylcholine is often used for its lipolytic effects, working to dissolve fat cells for elimination.
- Potential complications include vasovagal reactions
Face Design with Aesthefill(Poly Lactic Acid)Yong Hyun KWON
Aesthefill is made of PLA which stimulates collagen synthesis.
This presentation is about characteristics of Aesthefill and how to use it for Aesthetic Medicine.
You can watch procedure video on YouTube
(https://youtu.be/4MT5a6BWhxE)
This document provides an overview of cosmetic surgery procedures and techniques. It discusses the history of plastic surgery dating back to ancient times and developments in the 19th century. Specific procedures like facelifts, cheek augmentation, rhinoplasty, and blepharoplasty are described. Complications that can occur are infections, nerve damage, scarring, and dissatisfaction with results. The costs of common cosmetic surgeries are provided, ranging from approximately Rs. 40,000 for cheiloplasty to over Rs. 4,00,000 for a forehead lift. Overall benefits of cosmetic surgery include improved physical appearance and self-confidence, though maintenance is required and results may not be permanent.
This document discusses non-surgical face and body lifting using PDO lifting threads. It describes the mechanism of action, key advantages like minimal invasiveness and long lasting results. It provides protocols and recommended thread types for lifting different areas of the face like the brows, nasolabial folds and neck. It also discusses body lifting protocols and thread recommendations for areas like the breasts, arms, abdomen and legs. Before and after photos demonstrate the lifting effects on skin laxity.
1) Laser hair removal works by emitting a gentle light beam that is absorbed by the hair follicle, transforming the light energy to heat to permanently destroy the follicle while leaving the skin unharmed.
2) It requires multiple treatments over 9-15 months as only 10-20% of hairs are in the treatable growth phase at a given time and there are hundreds of thousands of follicles in any body area.
3) The main risks are burns, scarring, and discoloration, which can be prevented by avoiding tanning before and after treatments and informing staff of any pain over level 4 during the procedure.
This paper by Dr. Patrick Treacy Medical Director Ailesbury Clinics Ltd. sought to establish the efficacy and safety profile the dermal filler, calcium hydroxylapatite filler in the treatment of atrophic acne scars. Forty two subjects with differing degrees of atrophic acne scars were treated with this filler over an eighteen month period and the results are published below
Microblading is a semi permanent tattoo technique which involves the use of needles to give you thick luscious eye brows.Each stroke is created by hand by a trained expert to enhance and reshape the brows.A handheld tool is used instead of a tattoo machine which deposits pigment in the superficial layers of the skin that's why it lightens quickly.Initially your eyebrows might look quite dark but gradually matches the shade which goes with your skin.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing microblading in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
This document provides information about mesotherapy, including its history, indications, contraindications, drugs used, and complications. Some key points:
- Mesotherapy involves injecting small doses of medications into the mesoderm layer of skin to treat dermatological or internal lesions.
- It was first suggested by Dr. Michel Pistor in 1958 as a treatment between allopathic and homeopathic therapies.
- Common indications include aesthetic treatments like lipolysis and cellulite reduction, as well as pain management.
- Phosphatidylcholine is often used for its lipolytic effects, working to dissolve fat cells for elimination.
- Potential complications include vasovagal reactions
Face Design with Aesthefill(Poly Lactic Acid)Yong Hyun KWON
Aesthefill is made of PLA which stimulates collagen synthesis.
This presentation is about characteristics of Aesthefill and how to use it for Aesthetic Medicine.
You can watch procedure video on YouTube
(https://youtu.be/4MT5a6BWhxE)
This document provides an overview of cosmetic surgery procedures and techniques. It discusses the history of plastic surgery dating back to ancient times and developments in the 19th century. Specific procedures like facelifts, cheek augmentation, rhinoplasty, and blepharoplasty are described. Complications that can occur are infections, nerve damage, scarring, and dissatisfaction with results. The costs of common cosmetic surgeries are provided, ranging from approximately Rs. 40,000 for cheiloplasty to over Rs. 4,00,000 for a forehead lift. Overall benefits of cosmetic surgery include improved physical appearance and self-confidence, though maintenance is required and results may not be permanent.
This document discusses non-surgical face and body lifting using PDO lifting threads. It describes the mechanism of action, key advantages like minimal invasiveness and long lasting results. It provides protocols and recommended thread types for lifting different areas of the face like the brows, nasolabial folds and neck. It also discusses body lifting protocols and thread recommendations for areas like the breasts, arms, abdomen and legs. Before and after photos demonstrate the lifting effects on skin laxity.
1) Laser hair removal works by emitting a gentle light beam that is absorbed by the hair follicle, transforming the light energy to heat to permanently destroy the follicle while leaving the skin unharmed.
2) It requires multiple treatments over 9-15 months as only 10-20% of hairs are in the treatable growth phase at a given time and there are hundreds of thousands of follicles in any body area.
3) The main risks are burns, scarring, and discoloration, which can be prevented by avoiding tanning before and after treatments and informing staff of any pain over level 4 during the procedure.
The document discusses skin anatomy and chemical peeling. It describes the layers of the skin - epidermis, dermis and hypodermis. It then covers chemical peeling in depth, including the different depths, agents used, and their mechanisms and effects. Glycolic, lactic, mandelic and salicylic acids are specifically compared in terms of their molecular size, penetration, concentrations used, and indications.
This document provides an overview of chemical peels, including their history, ingredients, types, applications, contraindications, expected effects, and techniques. It discusses how chemical peels have been used since ancient Egypt to remove the outer layers of skin and promote new, healthier skin growth. The document then covers the specific ingredients and strengths of different peel types, from mild AHA peels to medium-depth peels using TCA to deep peels with phenol. It notes the appropriate applications and side effects of different strength peels.
If you want plumper and fuller lip,lip fillers are for you.They are bio compatible injectable collagen which are injected in your lips to give it a more fuller and enhanced look.They are basically hyaluronic acid which has volumizing effect.Your lips might look swollen for a week after the treatment but these symptoms subside eventually.Juvederm and Restylane are the commonly used lip fillers that are approved by FDA.You will likely need some follow up sessions after 6 months or even a year.The whole treatment takes upto an hour and effect usually shows after 15 days.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing lip fillers and lip augmentation procedures in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
Cheek Fillers|Facial Aesthetic| Facial Aesthetic by Dr Rajat Sachdeva| Facial...Dr. Rajat Sachdeva
Cheek Fillers rejuvenate the cheeks and to regain last volume.
Autologous Fat Injection, where your own fat harvested from some other area can be used to restore volume of cheeks.
Some other fillers like Hyaluronic acid, Ca Hydroxide and Polymethyl Metacrylate are injected with fine needles in the target area eliminate wrinkles and enhances cheeks volume.
This document provides information about radio frequency skin tightening treatments. It discusses how advances in non-invasive cosmetic treatments now allow people to reduce signs of aging without surgery. Radio frequency skin tightening uses thermal energy to stimulate collagen production and tighten skin in a non-invasive manner. While not as effective as surgery, it can provide mild to moderate skin tightening with little downtime. The document examines various radio frequency devices and how they work to tighten skin through collagen remodeling without surgery. It aims to help readers understand if a non-invasive treatment like radio frequency skin tightening may be right for their aesthetic goals and skin concerns.
The document discusses Fine Thread Contour (F.T.C.), a cosmetic technique that lifts and tightens sagging skin using bio-absorbable and antimicrobial filament threads. F.T.C. stimulates collagen production to instantly lift the face and body contours, resulting in a more youthful complexion. It has minimal downtime, little pain, and is safe and effective for wrinkles, lifting, firming, shaping, and tightening various areas of the face and body. The technique involves inserting thin threads into the dermis to trigger wound healing and collagen production without surgery or permanent threads.
Derma fillers are gel like substances that are injected beneath the skin to restore lost volume,smooth lines and soften creases, or enhance facial contours.They can be used as "volumizers" plumping and lifting cheeks,chins,jawlines and temples, filling out thin lips.Mostly Hylarudonic acid fillers like Juvederm are used.The procedure takes around 30-45 minutes and patients can see results in about 10 days-2weeks.
Derma Fillers are done at Dr Sachdeva's Dental clinic and Facial aesthetic centre in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
Laserklinic offers dermal filler treatments to minimize fine lines and wrinkles and lift the brow and cheek areas using hyaluronic acid fillers. The fillers replenish lost volume, plumping lines for long-lasting youthful results. They offer four types of dermal fillers and an expert team will determine the best treatment during a complimentary consultation. Dermal fillers are injected into the dermis and use hyaluronic acid, which dissolves naturally over 6 months to a year.
Microdermabrasion uses a closed vacuum system to gently exfoliate the top layer of dead skin cells through spraying aluminum oxide crystals onto the skin, then vacuuming them away along with exfoliated skin. It promotes new skin cell growth, resulting in smoother, clearer skin. Microdermabrasion machines work by sending crystals to the skin at high speed for exfoliation, then sucking away spent crystals and exfoliated skin. It can help with various skin conditions like acne, wrinkles, and sun damage through regular treatments. There are three main types of microdermabrasion machines that use crystals, lasers, or diamonds to penetrate the skin.
MIcro Lift Threads : Latest Revelation in Face and Body Lift http://spectroni...Spectronix Group
Micro Thread Lift (Reandne) is the most Novel Thread Procedure having lots of advantages over Previous Threads based Procedure.
The procedure is performed under Local Anesthetic Cream and has the following advantages for Face Contouring, Neck Lift, Wrinkle Treatment, Breast firming and lifting, Hip up, Saddle Bags and abdomen lift.
The procedure is SAFE, Non Surgical, Shorter Procedure Time, Use of only topical Anesthesia, No downtime, Immediate Effect (3-4 days after procedure). http://spectronixglobal.com/
This document provides information on advanced dermal fillers, including:
- Anatomy of the skin and changes that occur with aging
- Properties and uses of hyaluronic acid
- Injection techniques for dermal fillers like threading, fanning, and cross-hatching
- Treatment of areas like tear troughs, cheeks, and lips with dermal fillers
- Potential side effects and complications of treatments
- Case examples showing before and after photos of treatments
Medi-facial or Medical Facial is a facial,which is done under the supervision of a dermatologist, using skin friendly ingredients and medically proven to benefit skin in the long term. Medi-facial is based on vitamins, antioxidants, alpha hydroxy acids (AHAs).A standard facial does not treat the skin.It only provides pampering the skin.The ingredients which are used for medi facial provides an instant brightening effect as well as anti- aging benefits in the long term, with no side effects.
facelift without surgery can be done by
Botox
ultherapy
laser
threadlifts
LED
laser skin resurfacing
fillers
All these are age defying non surgical facelift alternatives
No risk of surgery is involved.These treatments encourages increased collagen production or remodelling of existing collagen.Supportive underlying tissues of the skin contract,resulting in tighter,more uplifted appearance of the skin.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing facelift without surgery in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
The BB Glow facial treatment involves micro-needling the skin and infusing it with a BB cream containing vitamins and peptides. This provides temporary improvements to skin appearance such as reducing fine lines, uneven tone, and giving a brighter complexion. While safe for most, those with active skin conditions, recent procedures, or sun exposure should avoid it. The treatment takes 60-90 minutes and involves cleansing, exfoliating, numbing, micro-needling, applying several layers of serum, with mild redness as the only expected side effect. Post-care focuses on hydration and avoiding irritation for optimal results.
Choosing the right dermal filler involves discussing your goals with an experienced injector, understanding the differences between fillers, and being aware of risks. The document discusses how hyaluronic acid fillers like Juvederm and Restylane last about a year and are used for smaller lines and lips, while Radiesse and Sculptra provide more volume and last longer. It emphasizes choosing an experienced injector to avoid issues with placement or overfilling.
Thread lift treatments are a non-surgical alternative to facelifts that involve injecting dissolvable threads into the skin to tighten it. The threads provide an immediate lifting effect and stimulate collagen, elastin, and hyaluronic acid production for continued tightening over time. Results can last 1-2 years. The procedure causes minor bruising or swelling that fades after a few days. Thread lifts can lift skin on the face, neck, arms, and buttocks.
Paper - Motor Insurance - Tariff, Detariff and Beyond... (India)Peeyush Agarwal
This document discusses issues with India's motor insurance tariff system and proposes simplifications. It notes that while the tariff was abolished in 2007, the industry still operates with a tariff mindset. It analyzes complexities and anomalies in the tariff provisions regarding vehicle classifications, trailer coverage, and policy formats. The document recommends simplifying these provisions, removing residual parts of the tariff, and allowing the industry to develop based on market demand and risk assessment rather than tariff rates. It suggests replacing legal language with plain language understandable to customers to prevent misselling.
Presentazione nell'ambito del corso di Sistemi Operativi Avanzati 14/15 della magistrale in Informatica dell'Università degli Studi di Salerno. Autori: Giovanni Grano & Gino Farisano
The document discusses skin anatomy and chemical peeling. It describes the layers of the skin - epidermis, dermis and hypodermis. It then covers chemical peeling in depth, including the different depths, agents used, and their mechanisms and effects. Glycolic, lactic, mandelic and salicylic acids are specifically compared in terms of their molecular size, penetration, concentrations used, and indications.
This document provides an overview of chemical peels, including their history, ingredients, types, applications, contraindications, expected effects, and techniques. It discusses how chemical peels have been used since ancient Egypt to remove the outer layers of skin and promote new, healthier skin growth. The document then covers the specific ingredients and strengths of different peel types, from mild AHA peels to medium-depth peels using TCA to deep peels with phenol. It notes the appropriate applications and side effects of different strength peels.
If you want plumper and fuller lip,lip fillers are for you.They are bio compatible injectable collagen which are injected in your lips to give it a more fuller and enhanced look.They are basically hyaluronic acid which has volumizing effect.Your lips might look swollen for a week after the treatment but these symptoms subside eventually.Juvederm and Restylane are the commonly used lip fillers that are approved by FDA.You will likely need some follow up sessions after 6 months or even a year.The whole treatment takes upto an hour and effect usually shows after 15 days.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing lip fillers and lip augmentation procedures in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
Cheek Fillers|Facial Aesthetic| Facial Aesthetic by Dr Rajat Sachdeva| Facial...Dr. Rajat Sachdeva
Cheek Fillers rejuvenate the cheeks and to regain last volume.
Autologous Fat Injection, where your own fat harvested from some other area can be used to restore volume of cheeks.
Some other fillers like Hyaluronic acid, Ca Hydroxide and Polymethyl Metacrylate are injected with fine needles in the target area eliminate wrinkles and enhances cheeks volume.
This document provides information about radio frequency skin tightening treatments. It discusses how advances in non-invasive cosmetic treatments now allow people to reduce signs of aging without surgery. Radio frequency skin tightening uses thermal energy to stimulate collagen production and tighten skin in a non-invasive manner. While not as effective as surgery, it can provide mild to moderate skin tightening with little downtime. The document examines various radio frequency devices and how they work to tighten skin through collagen remodeling without surgery. It aims to help readers understand if a non-invasive treatment like radio frequency skin tightening may be right for their aesthetic goals and skin concerns.
The document discusses Fine Thread Contour (F.T.C.), a cosmetic technique that lifts and tightens sagging skin using bio-absorbable and antimicrobial filament threads. F.T.C. stimulates collagen production to instantly lift the face and body contours, resulting in a more youthful complexion. It has minimal downtime, little pain, and is safe and effective for wrinkles, lifting, firming, shaping, and tightening various areas of the face and body. The technique involves inserting thin threads into the dermis to trigger wound healing and collagen production without surgery or permanent threads.
Derma fillers are gel like substances that are injected beneath the skin to restore lost volume,smooth lines and soften creases, or enhance facial contours.They can be used as "volumizers" plumping and lifting cheeks,chins,jawlines and temples, filling out thin lips.Mostly Hylarudonic acid fillers like Juvederm are used.The procedure takes around 30-45 minutes and patients can see results in about 10 days-2weeks.
Derma Fillers are done at Dr Sachdeva's Dental clinic and Facial aesthetic centre in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
Laserklinic offers dermal filler treatments to minimize fine lines and wrinkles and lift the brow and cheek areas using hyaluronic acid fillers. The fillers replenish lost volume, plumping lines for long-lasting youthful results. They offer four types of dermal fillers and an expert team will determine the best treatment during a complimentary consultation. Dermal fillers are injected into the dermis and use hyaluronic acid, which dissolves naturally over 6 months to a year.
Microdermabrasion uses a closed vacuum system to gently exfoliate the top layer of dead skin cells through spraying aluminum oxide crystals onto the skin, then vacuuming them away along with exfoliated skin. It promotes new skin cell growth, resulting in smoother, clearer skin. Microdermabrasion machines work by sending crystals to the skin at high speed for exfoliation, then sucking away spent crystals and exfoliated skin. It can help with various skin conditions like acne, wrinkles, and sun damage through regular treatments. There are three main types of microdermabrasion machines that use crystals, lasers, or diamonds to penetrate the skin.
MIcro Lift Threads : Latest Revelation in Face and Body Lift http://spectroni...Spectronix Group
Micro Thread Lift (Reandne) is the most Novel Thread Procedure having lots of advantages over Previous Threads based Procedure.
The procedure is performed under Local Anesthetic Cream and has the following advantages for Face Contouring, Neck Lift, Wrinkle Treatment, Breast firming and lifting, Hip up, Saddle Bags and abdomen lift.
The procedure is SAFE, Non Surgical, Shorter Procedure Time, Use of only topical Anesthesia, No downtime, Immediate Effect (3-4 days after procedure). http://spectronixglobal.com/
This document provides information on advanced dermal fillers, including:
- Anatomy of the skin and changes that occur with aging
- Properties and uses of hyaluronic acid
- Injection techniques for dermal fillers like threading, fanning, and cross-hatching
- Treatment of areas like tear troughs, cheeks, and lips with dermal fillers
- Potential side effects and complications of treatments
- Case examples showing before and after photos of treatments
Medi-facial or Medical Facial is a facial,which is done under the supervision of a dermatologist, using skin friendly ingredients and medically proven to benefit skin in the long term. Medi-facial is based on vitamins, antioxidants, alpha hydroxy acids (AHAs).A standard facial does not treat the skin.It only provides pampering the skin.The ingredients which are used for medi facial provides an instant brightening effect as well as anti- aging benefits in the long term, with no side effects.
facelift without surgery can be done by
Botox
ultherapy
laser
threadlifts
LED
laser skin resurfacing
fillers
All these are age defying non surgical facelift alternatives
No risk of surgery is involved.These treatments encourages increased collagen production or remodelling of existing collagen.Supportive underlying tissues of the skin contract,resulting in tighter,more uplifted appearance of the skin.
Dr Sachdeva's Dental clinic and Facial aesthetic centre is one of the leading clinics performing facelift without surgery in Delhi. So hurry up and come book an appointment with us at Dr.Sachdeva’s Dental Institute, Ashok Vihar, Delhi which has state of the art clinic and all the latest and advanced equipments.
To book an appointment contact:
Dr. Rajat Sachdeva
Director & Mentor
Dr Sachdeva’s Dental Aesthetic And Implant Institute
I 101, Ashok Vihar Phase 1, Delhi- 110052
Contact us at
Phone : +919818894041,01142464041
Our Websites:
www.sachdevadentalcare.com
www.dentalimplantindia.co.in
www.dentalclinicindelhi.com
www.dentalcoursesdelhi.com
Facebook- dentalcoursesdelhi
Youtube- drrajatsachdeva
Linkedin- drrajatsachdeva
Slideshare- Dr Rajat Sachdeva
Twitter Page- drrajatsachdeva
Instagram page- surgicalmasterrajat
The BB Glow facial treatment involves micro-needling the skin and infusing it with a BB cream containing vitamins and peptides. This provides temporary improvements to skin appearance such as reducing fine lines, uneven tone, and giving a brighter complexion. While safe for most, those with active skin conditions, recent procedures, or sun exposure should avoid it. The treatment takes 60-90 minutes and involves cleansing, exfoliating, numbing, micro-needling, applying several layers of serum, with mild redness as the only expected side effect. Post-care focuses on hydration and avoiding irritation for optimal results.
Choosing the right dermal filler involves discussing your goals with an experienced injector, understanding the differences between fillers, and being aware of risks. The document discusses how hyaluronic acid fillers like Juvederm and Restylane last about a year and are used for smaller lines and lips, while Radiesse and Sculptra provide more volume and last longer. It emphasizes choosing an experienced injector to avoid issues with placement or overfilling.
Thread lift treatments are a non-surgical alternative to facelifts that involve injecting dissolvable threads into the skin to tighten it. The threads provide an immediate lifting effect and stimulate collagen, elastin, and hyaluronic acid production for continued tightening over time. Results can last 1-2 years. The procedure causes minor bruising or swelling that fades after a few days. Thread lifts can lift skin on the face, neck, arms, and buttocks.
Paper - Motor Insurance - Tariff, Detariff and Beyond... (India)Peeyush Agarwal
This document discusses issues with India's motor insurance tariff system and proposes simplifications. It notes that while the tariff was abolished in 2007, the industry still operates with a tariff mindset. It analyzes complexities and anomalies in the tariff provisions regarding vehicle classifications, trailer coverage, and policy formats. The document recommends simplifying these provisions, removing residual parts of the tariff, and allowing the industry to develop based on market demand and risk assessment rather than tariff rates. It suggests replacing legal language with plain language understandable to customers to prevent misselling.
Presentazione nell'ambito del corso di Sistemi Operativi Avanzati 14/15 della magistrale in Informatica dell'Università degli Studi di Salerno. Autori: Giovanni Grano & Gino Farisano
Reversal of a HLA dermal filler induced facial artery occlusionDr. Patrick J. Treacy
Severe vascular adverse events, such as occlusion, can occur after treatment with dermal fillers in the glabellar and nasolabial regions. The author proposes that late onset vascular occlusion may be caused by hyaluronic acid expanding and compressing underlying arteries after injection. To treat impending necrosis from filler-induced vascular occlusion, the author recommends higher than normal doses of hyaluronidase, intravenous steroids, and other measures to increase blood flow and oxygen delivery. While most adverse reactions are mild and transient, practitioners must understand vascular anatomy and have protocols in place to promptly treat more serious complications like vascular occlusion.
ADOdb and PDO are both database abstraction libraries for PHP that allow developers to write database-independent code. ADOdb hides database specifics and provides a consistent API, additional functions, and better performance compared to PDO. Both libraries establish database connections using object-oriented methods and execute SQL queries by iterating through result sets. While PDO focuses only on basic data access and prepared statements, ADOdb offers more advanced features like pagination, blob handling, and error handling.
Dermal fillers can help restore volume and fullness to the skin. Learn what happens in this cosmetic procedure as The Victorian Cosmetic Institute gives an overview on facial volume loss and dermal fillers.
This document discusses the different categories of facial expressions: sadness and agony, anger, surprise and fear, disgust and contempt, and happiness. For each category, it identifies the key facial muscle movements and positions that are involved in expressing that emotion. For example, sadness is recognized by glaring eyes, raised upper eyelids, and lowered and brought together eyebrows. Anger involves a tightly clenched jaw, thinning of lips, and possibly an exposed rectangular mouth shape. Surprise and fear raise the upper eyelids and eyebrows and can cause a dropped jaw.
This document summarizes the major arteries and veins supplying the head and neck. It begins by listing the common carotid, external carotid, internal carotid, and subclavian arteries. It then describes the origins, branches, and relations of these arteries. It also discusses the major veins that drain the head and neck, including the external jugular, internal jugular, retromandibular and subclavian veins. It provides diagrams to illustrate the anatomy.
The document discusses the muscles of facial expression, including their classification, attachments, nerve supply, and actions. It covers key muscles like the orbicularis oculi and orbicularis oris, which close the eyelids and lips, respectively. It also mentions clinically important topics like testing of the facial nerve (CN VII) and the potential to create dimples artificially by modifying the zygomaticus major muscle.
The document describes the facial muscles, including their origins, insertions and actions. It lists and provides details on the muscles of the scalp, eyelids, nose, mouth and other areas. The orbicularis oculi, corrugator supercilii, levator palpebrae superioris and other orbital muscles are described. The document also outlines the nasal muscles like the nasalis and dilatator naris muscles. The oral group includes the orbicularis oris, buccinator and muscles that depress or elevate parts of the lips and mouth.
The Art of Liquid Face Lift (Dermal Fillers)Osama Moawad
Soft tissue fillers are flexible substances that can be injected into the skin to improve the appearance of fine lines and wrinkles, plump lips, fill hollow cheeks, repair various facial imperfections, improve scars, and elevate deep folds. Perhaps nothing is more gratifying for cosmetic patients than having an immediate correction of rhytides or scars as a result of the injection of a dermal filler The result is a smoother, more youthful appearance with minimal "downtime" and maximum safety. Prof. Moawad uses a variety of soft tissue fillers, including, hyaluronic acid, and autologous fat (one's own fat) among others. Since filler substances do not involve major surgery and are generally cost-effective, men and women are using these youth-enhancing techniques more than ever. With the increasing desire for people to achieve a more youthful appearance, the aging baby boomer population, and the increased demand for "lunch-time procedures," the pharmaceutical market has responded by providing the cosmetic surgeon with an increasing number of options to meet the demands of the cosmetic patient.
1. The face contains 17 muscles that are innervated by the facial nerve (CN VII) and control facial expressions. These include muscles around the eyes, nose, mouth, and other areas.
2. Damage to the facial nerve can cause total paralysis of the muscles on one side of the face, as seen in Bell's palsy. This prevents blinking, smiling, eye closing and other facial movements.
3. The orbicularis oculi muscle around the eye is important, as injury can cause ectropion where the lower eyelid droops and epip
The document provides an overview of the arteries of the face. It notes that the face is supplied by branches of the external carotid artery including the facial artery, transverse facial artery, and maxillary artery. It also discusses the internal carotid artery and its terminal branch, the ophthalmic artery, which gives off the zygomaticofacial and dorsal nasal arteries that supply parts of the face. The anastomoses between the branches of the external and internal carotid arteries are mentioned as well.
Whether you are a doctor or a medical researcher, details regarding the face anatomy can help you explain your patients about the latest surgeries and medical actions that are taking place. Further, using excellent Face anatomy PowerPoint Templates can instantly easy your effort and make the overall explanation process instant. More information: http://www.medicalppttemplates.com/medical-ppt-templates.aspx/Face-Anatomy-173
The document summarizes the anatomy of the scalp, face, and muscles of facial expression. It describes the layers of the scalp, the occipitofrontalis muscle of the scalp, and the sensory and motor innervation of the scalp. It outlines the bones and muscles of the face, including the orbicularis oculi, nasalis, and orbicularis oris muscles. Finally, it briefly discusses the sensory and motor innervation of the face, including the trigeminal and facial nerves.
This document outlines the essential anatomy for facial injections. It discusses the muscle groups of the face including the muscles of mastication and facial expression. It describes the functional groups of facial muscles as either dilators or sphincters around the orifices. It also summarizes the attachment and function of individual muscles, wrinkle lines caused by specific muscles, injection sites and complications. Furthermore, it covers the blood supply and innervation of the face.
CaHA (Radiesse) study in moderate to severe atrophic acne scarringDr. Patrick J. Treacy
This study sought to establish the efficacy and safety of dermal fillers, especially calcium hydroxyapatite, in treating atrophic acne scars. Twenty-seven subjects with atrophic acne scars were treated with calcium hydroxyapatite filler over twelve months. Most acne scars responded well, with 22% showing 75% improvement and 48% showing 50% improvement. Comparatively, a hyaluronic acid treatment led to only 3% and 9% improvement respectively. The study concluded that calcium hydroxyapatite provides a safe and effective method for treating atrophic acne scars and may have longer term effects through volume replenishment and possible neocollagenesis.
Calcium Hydroxylapatite Over a Decade of Clinical Experiencekpyu
Background: Calcium hydroxylapatite is one of the most well-studied dermal fillers worldwide and has been
extensively used for the correction of moderate-to-severe facial lines and folds and to replenish lost volume.
A 22-year-old woman presented with hypotrophic labia majora and a protruding clitoral hood after undergoing surgical reduction of the labia minora. She was treated with injections of diluted calcium hydroxylapatite (CaHA) in two sessions, 6 weeks apart, to augment the labia majora and mons pubis. At the 3-month follow-up, a significant improvement in the appearance of the external genitalia was observed with no serious side effects. The results lasted beyond 12 months. The author describes CaHA as a valuable, well-tolerated treatment option for aesthetic improvement of the female genitalia due to its ability to stimulate collagen production and correct volume deficiency with minimal downt
Dr Patrick Treacy explains how the use of a combination of
restorative dermal techniques allowed him to address the
poor skin texture and facial sagging in a patient with cancer
related cachexia
The DUBLiN Lift: To establish the clinical effectiveness of combining five treatments in the rejuvenation of the ageing face in an effort to increase aesthetic effect, patient safety, and reduce laser downtime.
It concludes that although fractionalised CO2 laser resurfacing is recognised as the gold standard procedure for tissue that has lost its elasticityit has adverse risks and does not adequately address the problems associated with chronological aging. He addresses the requirement to apply adjunct methods such as plasma rich platelets to address nasolabial or marionette lines and volume deficits resulting from the loss and repositioning of facial fat. It establishes the benefit of using other facial rejuvenating therapies including microneedling, PRP growth factors, 633 nm light to limit the depth of laser penetration and decrease the risk of scarring and permanent pigmentary alteration. The novel technique is called the DUBLiN facelift as an acronym of the procedures involved: Dermaroller, UltraPulse laser, Blood growth factors, Light (near-red 633 nm), and Neurotoxin.
A Randomized, Split-Face, Histomorphologic Study Comparing a Volumetric Calci...kpyu
Soft-tissue augmentation with dermal fillers is a popular, minimally invasive aesthetic procedure. In 2012, in the USA, most non-surgical augmentation treatments performed with a dermal filler used a product based on hyaluronic acid (HA), with the second most popular type being the calcium hydroxylapatite (CaHA)-based filler, Radiesse® (Merz Pharmaceuticals GmbH, Frankfurt, Germany), hereafter referred to as CaHA gel matrix.
Cancer-related cachexia causes devastating changes to facial structure such as muscle wasting and fat loss. While pharmaceuticals and nutrition have addressed total body mass loss, little research was done on restoring facial aesthetics. The author describes using a combination approach called the DUBLiN Lift to treat a cachexic cancer patient, combining hyaluronic acid fillers, platelet-rich plasma growth factors, dermal needling, fractional CO2 resurfacing, and red light therapy to address volume loss, poor skin texture, and sagging caused by long-term cachexia. This multiprocedure approach aimed to stimulate collagen production through multiple established techniques and appeared to successfully restore the patient's facial volume and quality of life.
Synthetic fillers for facial rejuvenationNhat Nguyen
This document discusses synthetic fillers used for facial rejuvenation. It begins by providing statistics on the popularity and growth of soft tissue filler procedures. It then discusses several synthetic fillers - calcium hydroxyapatite (CaHA), poly-L-lactic acid (PLLA), polymethyl methacrylate (PMMA), and silicone. Specifically, it outlines the composition, FDA approval history, injection techniques, and benefits of CaHA and PLLA, which provide long-lasting volume replacement through biostimulation of collagen production. Complications are rare but can include nodules, which can be treated through massage or injection of other substances.
Radiesse and Ellanse are considered biostimulant dermal fillers as they stimulate collagen production in addition to providing immediate volume restoration. Radiesse contains calcium hydroxylapatite microspheres suspended in a gel carrier that provide both immediate correction and induce new collagen formation over time. Ellanse contains polycaprolactone microspheres that degrade slowly and stimulate collagen production. Both fillers have been shown to effectively treat areas such as the cheeks and folds with natural results and high patient satisfaction.
Article looks at 'Multi Procedural Approach to Facial Rejuvenation' as it combines Microneedling, Omnilux 633 Phototherapy, Blood group factors injection to stimulate neocollagenesis within facial area.
The DUBLiN Lift: To establish the clinical effectiveness of combining five treatments in the rejuvenation of the ageing face in an effort to increase aesthetic effect, patient safety, and reduce laser downtime.
Dr. Patrick Treacy reviews the results of a retrospective study concerning the correction of Bio-Alcamid lip filler product migration in nine separate cases
Dr Patrick Treacy shares some of his most challenging
aesthetic dermatological cases. This month, he talks about the reversal of a dermal filler facial arterial occlusion with hyaluronidase and intravenous steroids
A 20-year-old woman presented with nodular swellings in her lips that had been present for over two years after injection with the filler Bio-Alcamid. Previous treatments with steroids provided no relief from the worsening swellings. Surgical excision of the nodules was performed, and biopsies showed no foreign body giant cells or crystalline structures. Various treatments are discussed for filler complications including steroids, 5-FU, anti-inflammatories, and surgical excision when conservative therapies fail. Bio-Alcamid has been removed from the market in many countries due to significant reported adverse reactions.
A presentation about anti-aging creams giving a brief of aging, anti-aging cosmetics, some general and some modern anti-aging agents and their mechanism of action, some detailed info of marketed formulations
This document provides an overview of common cosmetic surgical and non-surgical procedures. It discusses facial aging factors and how skin type is analyzed. Non-surgical procedures like fillers and botulinum toxin are described, with fillers being used to minimize wrinkles and treat facial atrophy. The most common filler types are listed. Surgical procedures like brow lifts and rhinoplasty are outlined, detailing techniques, recovery times, and potential complications. Overall, the document serves as an introduction to analyzing the face and various aesthetic options available.
This document provides a history and overview of dermal fillers, focusing on hyaluronic acid fillers such as Restylane and Perlane. It discusses how early dermal fillers involved fat injections and collagen but were replaced by hyaluronic acid fillers. Restylane and Perlane are hyaluronic acid gels that differ in particle size and intended injection depth. Clinical studies showed they effectively corrected facial wrinkles and folds for 6 months and had a good safety profile. Proper treatment and storage procedures are outlined to ensure safe use of these dermal fillers.
Dr Treacy is considered one of the most influential aesthetic
practitioners in the world, having forever altered the field of
aesthetic medicine. With anecdotes taken from his extraordinary memoir – and reveals why he finally decided to lift the mask.
A 53-year-old Irish female presented with an intractable trigeminal neuralgia pain in the region of her left maxillary nerve (V2) who did not respond to pharmacotherapy including pregabalin 300mgs bd and gabapentin 300mgs bd. She had been admitted to hospital for one month for intravenous oxycodone hydrochloride. She had also more than fifty nerve blocks in the previous years and had undergone stereotactic gamma knife radiosurgery which had work for five months but later resulted in uncontrollable dysesthesia pain in the region of her left maxillary nerve. She defined this as a continual unpleasant sensation of something 'crawling' under her skin in her left periorbital. There was a sensation of intense pain in her left external nasal area and that of electric shock, burning, and pins and needles and left mental area.
One of aesthetic medicines most notable characters,
Dr Patrick Treacy shares some of his favourite anecdotes
from his extraordinary memoir and reveals why he finally
decided to lift the mask.
Although having a facial disfigurement secondary to trauma, a birthmark, a birth defect or some abnormality does not affect a patient’s health; society deems it often leads to stigmatisation and limitations of opportunities afforded to others.
Split earlobe injuries are relatively common in individuals with pierced ears. They result from various forms of trauma, including babies pulling earrings, spousal abuse, and heavy earrings. Complete lobe clefts usually occur from either sudden pull injuries or from chronic traction.
Dr Patrick Treacy shares some of his most challenging cases. This month he ta...Dr. Patrick J. Treacy
A 61-year-old Irish female, presented with complete pulled earlobes bilaterally as a consequence of possible low placement of original piercings and pendulous ear-rings. She wanted repair of the defect so she could begin to wear her earrings again. The patient was in no distress the defect had caused scar tissue along the involved cleft.
Dr Patrick Treacy shares some of his most challenging cases.
This month he talks about treating Cutaneous Malignant Melanoma. Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. They typically occur in the skin but may rarely occur in the mouth, intestines, or eye. In women they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with concerning changes including an increase in size, irregular edges, change in color, itchiness, or skin breakdown
A 32-year-old male patient presented with a large wart on his second finger and numerous warts on his right foot. Warts are a common skin infection caused by HPV that can persist for many years. Diagnosis of warts is usually not difficult to make clinically or histologically. Treatment options for warts include cryotherapy, which the author uses to treat digital warts, CO2 laser for foot warts, salicylic acid, photodynamic therapy, lasers, and other topical treatments. While many treatments are available, evidence for their efficacy is sometimes limited.
Dr Patrick Treacy on devices for dealing with post-pregnancy baby weightDr. Patrick J. Treacy
Pregnancy leads to many changes in a woman’s
body, mainly through the interaction of steroid
hormones, lactogen and cortisol on the underlying
tissues and structures. The growing foetus itself
causes mechanical change also by stretching
skin, muscle and fascia and demanding an increased
calorific supply. The amount of extra weight gained
during pregnancy varies among women.
1) The document describes a case of a 47-year-old man who developed gustatory sweating (Frey's syndrome) after undergoing endoscopic thoracic sympathectomy surgery 16 years prior.
2) Frey's syndrome causes sweating, flushing, and warming of the face and neck in response to eating. It is treated using botulinum toxin injections, which were effective in resolving the patient's symptoms.
3) Botulinum toxin injections of 3 mouse units per square centimeter is an effective, minimally invasive treatment for Frey's syndrome that can provide relief of symptoms for over 12 months.
Dr Patrick Treacy on combining therapies for optimal outcomes in treating the...Dr. Patrick J. Treacy
This paper looks at the possibility of combining five
established therapies in an attempt to address
common concerns related to facial ageing. The
therapies included microneedling, low dose
Ultralase laser, (PRP) plasma rich protein growth
factors, Omnilux 633 light and neurotoxins. The technique is
called the DUBLiN face-lift as an acronym of the procedures
involved. D Dermaroller U Ultralase Laser B Blood growth
factors Li Light (near red 633) N Neurotoxin.
The author compared this method to fractionalised laser
skin resurfacing (FLSR) in terms of reduction of photoageing
and overall aesthetic effect. Neurotoxin was used in
both studies.
Dr Patrick Treacy shares some of his most challenging cases. This month he talks about treating facial popular sebaceous hyperplasia. Sebaceous hyperplasia is a disorder of the sebaceous glands in which they become enlarged, producing yellow, shiny bumps on the face
Dr Patrick Treacy discusses dermal filler complications and how to deal with ...Dr. Patrick J. Treacy
At present, there’s a paucity of literature regarding both the prevention and management of serious events, despite the fact that these complications are the very things that patients and physicians both continually fear. Many physicians, (including myself), feel that corporate prefer not to address these issues and they are driven underground. Over the years, many of my colleagues have referred me their more serious problems and I consequently have developed a certain experience in this area. This insight into complications of dermal filler use will serve to highlight both of these problems and try to help one manage these complications if they should ever happen to you.
Dr. Patrick Treacy is chairman of several medical organizations focused on cosmetic medicine and aesthetic training. He has pioneered techniques for facial reconstruction and has trained over 800 medical professionals worldwide. Dr. Treacy will be giving a presentation at the British College of Aesthetic Medicine Conference on the risks of soft tissue fillers and the importance of proper injection technique to avoid complications like vascular occlusion.
This month sees the publication of Dr Patrick Treacy’s memoirs. Vicky Eldridge reveals what readers can expect from this fascinating insight into the life of one of the industry’s best-known doctors
‘Behind The Mask’ – The Extraordinary Story of The Irishman who Became Michae...Dr. Patrick J. Treacy
Dr. Patrick Treacy is a well-known face within the Aesthetic industry, both in the UK and Ireland, as well as the World. A loveable, Irish rogue with a charming, boyish smile and a cheeky demeanour, Patrick, (what better
name for an Irishman is there) is also a very accomplished and knowledgeable medical professional and humanitarian.
Dr Patrick Treacy on Diagnosis and Treatment of Malignant Melanoma Dr. Patrick J. Treacy
A 23-year-old Siberian female patient presented with a changing lesion on her abdomen. The patient stated the lesion was present for about two years and it started
off from within a freckle, which started to grow larger and somewhat darken in appearance. It had the clinical appearance of a melanoma and the dermoscopy three-point checklist (designed to allow non-experts not to miss detection of melanomas) was used to determine whether this had a high likelihood of malignancy. It included:
Asymmetry: asymmetry of colour and structure in one or
two perpendicular axes
Atypical network: pigment network with irregular holes
and thick lines
Blue-white structures: there was some evidence of blue-
white veil and regression structures
This document discusses a case of idiopathic scrotal calcinosis (ISC) in a 26-year-old male who presented with multiple asymptomatic scrotal nodules. Physical examination revealed multiple firm subcutaneous nodules of varying sizes within the scrotal wall. Histology showed calcifications within cystic spaces and a foreign body giant cell reaction, consistent with a diagnosis of scrotal calcinosis. ISC is a rare benign condition typically appearing in men aged 20-40 years as hard, yellowish nodules within the scrotal skin. Surgery is the treatment of choice for cosmetic reasons, as the nodules can affect quality of life.
Gene therapy can be broadly defined as the transfer of genetic material to cure a disease or at least to improve the clinical status of a patient.
One of the basic concepts of gene therapy is to transform viruses into genetic shuttles, which will deliver the gene of interest into the target cells.
Safe methods have been devised to do this, using several viral and non-viral vectors.
In the future, this technique may allow doctors to treat a disorder by inserting a gene into a patient's cells instead of using drugs or surgery.
The biggest hurdle faced by medical research in gene therapy is the availability of effective gene-carrying vectors that meet all of the following criteria:
Protection of transgene or genetic cargo from degradative action of systemic and endonucleases,
Delivery of genetic material to the target site, i.e., either cell cytoplasm or nucleus,
Low potential of triggering unwanted immune responses or genotoxicity,
Economical and feasible availability for patients .
Viruses are naturally evolved vehicles that efficiently transfer their genes into host cells.
Choice of viral vector is dependent on gene transfer efficiency, capacity to carry foreign genes, toxicity, stability, immune responses towards viral antigens and potential viral recombination.
There are a wide variety of vectors used to deliver DNA or oligo nucleotides into mammalian cells, either in vitro or in vivo.
The most common vector system based on retroviruses, adenoviruses, herpes simplex viruses, adeno associated viruses.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Selective alpha1 blockers are Prazosin, Terazosin, Doxazosin, Tamsulosin and Silodosin majorly used to treat BPH, also hypertension, PTSD, Raynaud's phenomenon, CHF
Allopurinol, a uric acid synthesis inhibitor acts by inhibiting Xanthine oxidase competitively as well as non- competitively, Whereas Oxypurinol is a non-competitive inhibitor of xanthine oxidase.
As the world population is aging, Health tourism has become vitally important and will be increased day by day. Because
of the availability of quality health services and more favorable prices as well as to shorten the waiting list for medical
services regionally and internationally. There are some aspects of managing and doing marketing activities in order for
medical tourism to be feasible, in a region called as clustering in a region with main stakeholders groups includes Health
providers, Tourism cluster, etc. There are some related and affecting factors to be considered for the feasibility of medical
tourism within this study such as competitiveness, clustering, Entrepreneurship, SMEs. One of the growth phenomenon
is Health tourism in the city of Izmir and Turkey. The model of five competitive forces of Porter and The Diamond model
that is an economical model that shows the four main factors that affect the competitiveness of a nation and its industries
in this study. The short literature of medical tourism and regional clustering have been mentioned.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
This presentation gives information on the pharmacology of Prostaglandins, Thromboxanes and Leukotrienes i.e. Eicosanoids. Eicosanoids are signaling molecules derived from polyunsaturated fatty acids like arachidonic acid. They are involved in complex control over inflammation, immunity, and the central nervous system. Eicosanoids are synthesized through the enzymatic oxidation of fatty acids by cyclooxygenase and lipoxygenase enzymes. They have short half-lives and act locally through autocrine and paracrine signaling.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
Storyboard on Acne-Innovative Learning-M. pharm. (2nd sem.) CosmeticsMuskanShingari
Acne is a common skin condition that occurs when hair follicles become clogged with oil and dead skin cells. It typically manifests as pimples, blackheads, or whiteheads, often on the face, chest, shoulders, or back. Acne can range from mild to severe and may cause emotional distress and scarring in some cases.
**Causes:**
1. **Excess Oil Production:** Hormonal changes during adolescence or certain times in adulthood can increase sebum (oil) production, leading to clogged pores.
2. **Clogged Pores:** When dead skin cells and oil block hair follicles, bacteria (usually Propionibacterium acnes) can thrive, causing inflammation and acne lesions.
3. **Hormonal Factors:** Fluctuations in hormone levels, such as during puberty, menstrual cycles, pregnancy, or certain medical conditions, can contribute to acne.
4. **Genetics:** A family history of acne can increase the likelihood of developing the condition.
**Types of Acne:**
- **Whiteheads:** Closed plugged pores.
- **Blackheads:** Open plugged pores with a dark surface.
- **Papules:** Small red, tender bumps.
- **Pustules:** Pimples with pus at their tips.
- **Nodules:** Large, solid, painful lumps beneath the surface.
- **Cysts:** Painful, pus-filled lumps beneath the surface that can cause scarring.
**Treatment:**
Treatment depends on the severity and type of acne but may include:
- **Topical Treatments:** Such as benzoyl peroxide, salicylic acid, or retinoids to reduce bacteria and unclog pores.
- **Oral Medications:** Antibiotics or oral contraceptives for hormonal acne.
- **Procedures:** Such as chemical peels, extraction of comedones, or light therapy for more severe cases.
**Prevention and Management:**
- **Cleanse:** Regularly wash skin with a gentle cleanser.
- **Moisturize:** Use non-comedogenic moisturizers to keep skin hydrated without clogging pores.
- **Avoid Irritants:** Such as harsh cosmetics or excessive scrubbing.
- **Sun Protection:** Use sunscreen to prevent exacerbation of acne scars and inflammation.
Acne treatment can take time, and consistency in skincare routines and treatments is crucial. Consulting a dermatologist can help tailor a treatment plan that suits individual needs and reduces the risk of scarring or long-term skin damage.
Dr. Tan's Balance Method.pdf (From Academy of Oriental Medicine at Austin)GeorgeKieling1
Home
Organization
Academy of Oriental Medicine at Austin
Academy of Oriental Medicine at Austin
Academy of Oriental Medicine at Austin
About AOMA: The Academy of Oriental Medicine at Austin offers a masters-level graduate program in acupuncture and Oriental medicine, preparing its students for careers as skilled, professional practitioners. AOMA is known for its internationally recognized faculty, award-winning student clinical internship program, and herbal medicine program. Since its founding in 1993, AOMA has grown rapidly in size and reputation, drawing students from around the nation and faculty from around the world. AOMA also conducts more than 20,000 patient visits annually in its student and professional clinics. AOMA collaborates with Western healthcare institutions including the Seton Family of Hospitals, and gives back to the community through partnerships with nonprofit organizations and by providing free and reduced price treatments to people who cannot afford them. The Academy of Oriental Medicine at Austin is located at 2700 West Anderson Lane. AOMA also serves patients and retail customers at its south Austin location, 4701 West Gate Blvd. For more information see www.aoma.edu or call 512-492-303434.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
Can Traditional Chinese Medicine Treat Blocked Fallopian Tubes.pptxFFragrant
There are many traditional Chinese medicine therapies to treat blocked fallopian tubes. And herbal medicine Fuyan Pill is one of the more effective choices.
“Environmental sanitation means the art and science of applying sanitary, biological and physical science principles and knowledge to improve and control the environment therein for the protection of the health and welfare of the public”.The overall importance of sanitation are to provide a healthy living environment for everyone, to protect the natural resources (such as surface water, groundwater, soil ), and to provide safety, security and dignity for people when they defecate or urinate .Sanitation refers to public health conditions such as drinking clean water, sewage treatment, etc. All the effective tools and actions that help in keeping the environment clean come under sanitation. Sanitation refers to public health conditions such as drinking clean water, sewage treatment. All the effective tools and actions that help in keeping the environment clean and promotes public health is the necessary in todays life.
Helminthiasis or Worm infestation in Children for Nursing students
Atrophic Acne Scarring and Dermal Filling
1. peer-review | fxxxxxxxxs |
dermal filler
treatment
For atrophic
acne scarring
Patrick Treacy presents the results of a study investigating
the efficacy of dermal fillers in the treatment of atrophic acne
scarring
ABSTRACT degrees of atrophic acne scarring were cohort. Eleven hyaluronic acid patients (85%
Full title treated with the CaHA filler over a 12‑month of total) showed a 0–25% improvement in
Problems encountered using dermal fillers, period. Thirteen patients were treated treated atrophic scars at 12 months.
particularly calcium hydroxylapatite, as a with low molecular weight cross-linked
treatment in acne scarring . hyaluronic acid in a comparative study. Conclusions
Dermal fillers, especially CaHA, can provide
Objectives Results a safe and efficacious method of treating
This article aims to establish the efficacy Most atrophic acne scars responded well atrophic acne scars. This compound appears
and safety profile of dermal fillers, especially to CaHA dermal filler treatment. Ice-pick to provide a longer-lasting effect owing
calcium hydroxyapatite (CaHA) in the scars were not treated. At 12-month to volume replenishment and possible
treatment of atrophic acne scars. evaluation, 22% of subjects showed a 75% neocollagenesis. The efficacy of hyaluronic
improvement, while 48% showed a 50% acid in repairing atrophic acne scars is not
Methods improvement. This compared to an average demonstrable.
Twenty-seven subjects with differing 0% improvement for the hyaluronic acid
Dr Patrick Treacy is
A
Medical Director of Ailesbury
Clinics Ltd and Ailesbury Hair
Clinics Ltd; Chairman of the cne occurs in approximately unhappiness, anxiety, and even suicidal thoughts as a
Irish Association of Cosmetic
Doctors and Irish Regional
95% of 16–17-year-old boys and 84% of result of their facial appearance5.
Representative of the British 16–17-year-old girls1. Although the
Association of Cosmetic
Doctors; European Medical
condition usually resolves by the Background
Advisor to Network Lipolysis mid‑20s, 1% of men and 5% of women For many years different treatment modalities have been
and the UK’s largest cosmetic still bear the signs of moderately severe used for the revision of atrophic acne scarring, with
website Consulting Rooms. He acne scarring at 40 years of age2. Some studies show varying degrees of success. Many controlled trials have
practices cosmetic medicine
in his clinics in Dublin, Cork, scarring of some degree may affect up to 95% of patients demonstrated that moderate to severe atrophic acne
London and the Middle East with acne3. The same study found that keloidal or scars can be safely improved through ablative fractional
hypertrophic truncal scarring was more common in CO2 laser resurfacing (fractional laser skin resurfacing;
email: ptreacy@gmail.com
men. This form of scarring is usually treated by using FLSR)6. Although FLSR is still the most popular
such measures as intralesional steroids, silicone therapeutic modality for the correction of acne scars, it is
sheeting, or vascular laser treatment. Atrophic scarring not always effective in all types of atrophic lesions7 — the
Keywords will often appear many years later, and can cause great more common type of defects encountered after
calcium hydroxyapatite,
hyaluronic acid, acne scars, distress in patients during their courtship years4. inflammatory acne. The use of higher energy levels
dermal fillers Affected patients report more social inhibition, might have improved the results, and also possibly
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induced significant adverse effects7. Over the past
decade, non-ablative laser resurfacing8–10, radiofrequency
(RF)11, and microneedling12 have been shown to create
some improvement in the appearance of these atrophic
scars. A number of autologous and non-autologous
techniques attempting dermal and subcutaneous
augmentation have been tried to improve the facial
aesthetic appearance. The autologous methods have
included dermal grafting, fat transfer13, 14, and implantation
of autologous fibroblasts, such as Isolagen®15.
There has been interest in non-autologous
augmentation by way of injections of hyaluronic acid
(HA), polymethylmethacrylate microspheres (PMMA),
and calcium hydroxylapatite (CaHA)16, 17. CaHA, the main
mineral component of Radiesse® (Merz Aesthetics, San
Mateo, CA) is a synthetic analogue of the inorganic salt
found in the human body as a constituent of bone and
teeth. The CaHA microspheres (25–45 µ) are suspended
in an aqueous carboxymethylcellulose carrier gel,
composed of cellulose, glycerin, and sterile water. None
of these materials should elicit a chronic inflammatory,
infectious or immune response. Multiple clinical and
histologic studies have tended to document its safety, migrate, and does not obscure diagnostic x-rays.
efficacy, and longevity in tissue17, 18. At the present time, the use of CaHA is approved by the
By its very composition, CaHA is designed to provide Food and Drug Administration (FDA) for the correction of
immediate correction and long-term biostimulatory moderate to severe facial wrinkles and folds19, 20. CaHA
neocollagenesis. Over time, the gel is absorbed, and also gained prominence during the period in which
fibroblasts appear and the process of neocollagenesis dermal fillers were being used for antiretroviral-induced
begins, stimulating the gradual growth of the patient’s facial lipoatrophy21, 22. It is known to cause persistent
own collagen. The nodules in a small percentage of people,
carboxymethylcellulose gel carrier especially if it is injected into the vermillion
volumises the ‘lost’ space and acts as a
Soft tissue filler use for acne border of the lips23. As many studies have
replacement filler; the microspheres scarring would be an attractive option established the biocompatibility and safety
stimulate neocollagenesis so that, as the to most practitioners as they require of CaHA in facial filling techniques21, the
gel dissipates, the spheres anchor into
little invasive technique and could be product has gained popularity in the US
the soft tissue. There, they serve as a and Europe for this indication, and more
scaffold for new collagen growth as early used in combination with other recently in the treatment of acne scarring24.
as 4 weeks post-injection, and then treatment modalities. HA has been used in aesthetic medicine
continue for up to at least 12 months17, 18. CaHA is not for a long time, and has an extended safety profile. In its
permanent, however. The CaHA microspheres are natural form HA has a short duration time in the tissue,
metabolised into calcium and phosphate ions through owing to enzymatic degradation and free radical
normal metabolic processes over 24 months. CaHA will metabolisation. To avoid these effects, HA gel is modified
not promote osteogenesis in soft tissues, does not through cross‑linking to form a water-insoluble polymer
hydrogel, more resistant to degradation, but with a similar
Table 1 Four-point grading scale biocompatibility as non-modified HA. Based on the
for acne scars experience of other authors, many of the available HA
preparations are too short-lived (approximately
Grade 1: Macular 3–6 months24, 25 to appropriately treat moderate to severe
Erythematous, hyper-, or hypopigmented marks acne scars) and use of such products for this purpose
would require a significant total injection volume over
Grade 2: Mild disease time, with frequent re-treatments, contributing to a
Mild atrophy, can be covered with make-up of facial hair greater total cost and time commitment for the patient.
More viscous forms of HA, such as Perlane® (Medicis
Grade 3: Moderate disease Aesthetics, Inc., Scottsdale, AZ) or Juvederm® Voluma
Moderate scarring, not covered by make-up, but can be (Allergan, Inc., Santa Barbara, CA), may be appropriate for
flattened by manual stretching of the skin patients with atrophic scars. The ideal filler for this
purpose would be long-lasting, biocompatible, and would
Grade 4: Severe disease not elicit further inflammation or granuloma formation
Scarring not flattened with manual stretching of the skin in skin already damaged by acne26.
Soft tissue filler use for acne scarring would be an
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study over a 1-year period. Patients were randomly
selected on the basis that they did not want to present for
laser resurfacing as a treatment for their problem. This
meant the patients were enrolled sporadically, rather
than entering the study at the same time. The subjects
ranged in age from 16–63 years, and all acne scarring
severity scores fell between 4 and 30 on the Goodman
system (Table 1). Patients were also evaluated using
digital photography and an improvement graduation
scale at each subsequent treatment visit, at 1, 3, 6, 12 and
24 months post-procedurally:
■■ 0 = no improvement
■■ 1 = 0–25% improvement
■■ 2 = 25–50% improvement
■■ 3 = 50–75% improvement
■■ 4 = 75–100% improvement
Figure 2 17-year-old male patient (A, B, C) before treatment with Radiesse, and (D, E) immediately after ■■ 5 = 100% improvement.
treatment. 1.3 ml CaHA was used Multiple acne scar grading classification systems of
varying complexities have been introduced. The most
attractive option to most practitioners as they require basic, practical system divides atrophic acne scars into
little invasive technique and could be used in three main types: icepick, rolling, and boxcar scars29
combination with other treatment modalities, such as (Figure 1). It is common for patients to have more than one
microneedling or laser resurfacing. Although studies type of scar.
have shown that HA injections do stimulate collagen Subscision of each atrophic scar was performed 1 week
formation in the short term, this effect is probably more
related to the physical act of injection, rather than to the
HA itself.
Subcision is a term introduced by Orentreich and
Orentreich27 to describe the minor surgical procedure for
treating depressed acne scars and wrinkles, using a
hypodermic needle inserted through a puncture in the
skin surface and its sharp edges manoeuvred under the
defect to make subcuticular cuts or ‘cisions’. The principle
of this procedure is to break the fibrotic strands, which
tether the scar to the underlying subcutaneous tissue.
The depression is lifted by the releasing action of the
procedure, as well as from connective tissue that forms
during the course of normal wound healing28.
Methods
A series of 27 patients (17 male, 10 female; skin phototypes
I–IV), with varying degrees of atrophic acne scarring, Figure 3 23-year-old female patient (A) during treatment with Radiesse, and (B) 2 weeks after
were treated in a single-centre, prospective, controlled treatment
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A series of 13 patients (7 male, 6 female; skin phototypes
I–IV) with varying degrees of atrophic acne scarring were
treated in a similar manner with low molecular weight
cross-linked HA, and monitored over a 12‑month period.
Patients were randomly selected on the basis that they
did not want to present for laser resurfacing as a
treatment for their problem.
Results
Twenty-seven patients entered this 12-month study.
Moderate to excellent clinical improvement was
observed after 4 weeks in almost all of the patients
studied (20 patients with score 4, 75–100%; siz patients
with score 3, 50–75%). One patient had score 1, 0–25%
improvement, while no subjects scored either 0 or 5. At
the 6-month assessment 12 patients (44% of total) had
score 4 (75–100% improvement) and 11 patients (40%) had
Figure 4 23-year-old male patient (A) before treatment with Radiesse, and (B) 2 weeks after treatment
score 3 (50–75% ). At 12-month evaluation, six patients
(22%) showed 75% improvement; 14 patients (48%)
prior to injection with CaHA to give a more uniform showed between 50% improvement, and five patients
aesthetic effect. Radiesse was injected using a 27 gauge (18%) showed a 25% improvement in treated atrophic
needle into the space left after subscision of the acne scars.
scar in the region of the mid- to deep dermis, although Thirteen patients entered the 12-month HA study. At
final placement also depended on the presence of 3‑month assessment, zero patients had score 4 (75–100%
fibrous and cystic tissue in this region of the skin. The improvement) and four patients (23%) had score 3 (50–
total volume of CaHA used varied with each patient, with
an end-point being agreed between patient and
physician. It was decided not to record the amount of
product used as this was not felt to be contributory to the
final result. Histologic evaluation of cutaneous biopsies
were not obtained before or during treatment, although it
was offered to at least one of the patients who had a
resultant adverse reaction. Betadine® cleansing was used
in most patients and doxycycline 100 mg for 2 days was
given as prophylaxis in 11 patients, who were felt to be at
risk of infection as they still appeared to have active acne.
One patient, who had a previous photoallergic reaction
to doxycycline, was prescribed Augmentin-Duo twice
daily for 2 days.
Subjects were not excluded from the study on the
basis of bleeding disorders or whether they were taking
anticoagulants/anti-inflammatory agents, as it was felt
that while the bruising may be unsightly, it would likely
improve overall healing. Patients who had received
synthetic collagen, HA, PMMA, CaHA, or autologous
fibroblast injections to treated areas within the previous
6 months were excluded from the study. Clinical
assessment scores were determined at each treatment
session and follow-up visit. Patient satisfaction surveys
and digital photography were used where they were
appropriate to both parties, although both were
considered subjective, with patients tending to focus on
the smallest detail and physicians photographically
favouring the better results. All patients were reviewed at
2 or 4 weeks post-treatment for a top-up of Radiesse, if
required. It was noted that 17 patients required a top-up of
at least 0.15 ml CaHA at one of the first two visits. Smaller
amounts (< 0.1 ml) were not recorded, as it was felt that the
patient may have seen some defects under deeper
scrutiny that were initially missed during the procedure. Figure 5 26-year-old old male patient (A) before treatment with CaHA and (B) 4 weeks after treatment
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75% ). At 6-month evaluation, 12 patients (92%) showed a
0–25% improvement.
The author felt both of the fillers initially provided a
simple physical volumising effect. There was a longevity
associated with the therapeutic effect of the calcium
hydroxylapatite (CaHA), probably secondary to the
duration of the filler and some level of neocollagenesis
noted in other studies. There was little evidence of
delayed biostimulatory effect of collagen formation
owing to HA injections, although the physical act of
injection and subcision was of some benefit to the
patient.
Side-effects of treatment were mostly limited in the
group to mild transient erythema, bruising or localised
oedema. Some patients required top up or remodelling
on initial review. One 23-year-old male patient (skin type
4, of Asian origin) with minimally active acne on a
previous trial developed cellulitis and later
desquamation.
Discussion Figure 6 Improvement rates in patient cohort treatment with CaHA
There are many methods that can be used in the
treatment of atrophic acne scarring. Most tend to replace
the volume lost by the atrophic effects of the acne. Newer
injectable fillers are biocompatible and safer, and can
provide an alternative means of treating acne scarring in
patients not opting for laser resurfacing. The author has
used the HA-based filler Matridex® (BioPolymer GmbH &
Co., Germany), CaHA, and the polyalkylimide Bio-
Alcamid® (Polymekon, Brindisi, Italy) for this purpose
over the years. Some of these fillers simply provide a
physical filling effect, while others induce a delayed
collagen stimulatory effect (e.g. CaHA and poly-L-lactic
acid). An ideal filling agent should restore atrophic
volume and stimulate the dermis to synthesise new
collagen for a long-lasting effect.
Based on the experience of this study, the author feels
CaHA is a suitable product for this purpose, showing a
clearly demonstrable benefit still present at 6–12 months.
A comparative study performed with HA preparations
showed the compound was not of medical or commercial
benefit to either the physician or patient, with most of the
product disappearing at only 6–12 weeks. More viscous
forms of HA, such as HyaCorp® (BioScience GmbH,
Germany) showed no extra benefit.
[AQ9: any limitations to this study?]
Conclusions Figure 6 Improvement rates in patient cohort treatment with HA
CaHA is biosynthetically produced and does not elicit a
chronic inflammatory or immune response. In vivo and
in vitro studies have established the biocompatibility and
safety of CaHA. No evidence of granuloma formation,
ossification, or foreign body reactions have been found in
long-term animal studies. CaHA implants have persisted
intact at the injection site in areas such as the face at up to
12–18 months. No skin testing is required for the
compound as company information states that no
animal or animal products are used in the manufacture
of the product, thus there is no risk of transmitting disease
or causing allergic reactions in patients who are sensitive
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