This study compared patient knowledge, satisfaction, and decision-making preferences regarding liver disease care in the USA, urban China (Beijing), and rural China (Hebei). A survey of 990 patients across the three regions found that mean knowledge and satisfaction scores were highest in the USA, followed by Beijing, and lowest in Hebei. US patients preferred shared decision-making more than Chinese patients, who generally preferred doctors to make decisions. Higher knowledge scores and preferences for shared decision-making correlated with greater satisfaction. Understanding these differences may help improve patient outcomes.
QUALITY OF LIFE AS A PREDICTOR OF POST OPERATIVE OUTCOME FOLLOWING REVASCULAR...Shantonu Kumar Ghosh
World Health Organization (WHO) defines quality of life as an individual’s perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns.8
QOL encompasses the concept of health-related quality of life (HRQOL) and other domains such as environment, family and work. HRQOL is the extent to which one’s usual or expected physical, emotional and social well-being is affected by a medical condition or its treatment.9
For patients suffering from peripheral arterial disease (PAD), quality of life (QoL) has become as important as medical outcome end points, such as mortality and morbidity, to evaluate the effect of disease and treatment.10
Carle Palliative Care Journal Club 1/15/2020Mike Aref
A journal club review and criticism of J Natl Cancer Inst. 2019 Dec 17. pii: djz233. doi: 10.1093/jnci/djz233 Emergency Department Visits for Opioid Overdoses Among Patients with Cancer by Jairam V, Yang DX, Yu JB, Park HS.
QUALITY OF LIFE AS A PREDICTOR OF POST OPERATIVE OUTCOME FOLLOWING REVASCULAR...Shantonu Kumar Ghosh
World Health Organization (WHO) defines quality of life as an individual’s perception of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards and concerns.8
QOL encompasses the concept of health-related quality of life (HRQOL) and other domains such as environment, family and work. HRQOL is the extent to which one’s usual or expected physical, emotional and social well-being is affected by a medical condition or its treatment.9
For patients suffering from peripheral arterial disease (PAD), quality of life (QoL) has become as important as medical outcome end points, such as mortality and morbidity, to evaluate the effect of disease and treatment.10
Carle Palliative Care Journal Club 1/15/2020Mike Aref
A journal club review and criticism of J Natl Cancer Inst. 2019 Dec 17. pii: djz233. doi: 10.1093/jnci/djz233 Emergency Department Visits for Opioid Overdoses Among Patients with Cancer by Jairam V, Yang DX, Yu JB, Park HS.
Carle Palliative Care Journal Club for 7/3/18Mike Aref
Journal club review of "Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial" by D. Hui et. al. in JAMA. 2017 Sep 19;318(11):1047-1056.
The goal of this webinar was to help hospice and healthcare professionals understand the history, philosophy, and practice of hospice and palliative care.
Efficacy and safety of traditional Chinese medicine kidney-nourishing formula...LucyPi1
Abstract Objective: Finding an effective therapy against Alzheimer’s disease (AD) has been associate increasingly pressing issue and traditional Chinese medicine (TCM) is widespread in the prevention and treatment of AD in China. The aim of this study was to judge the efficaciousness and safety of TCM kidney-nourishing (the changes of pathological state of kidney deficiency by means of TCM treatment and so on) formula (TKNF) for AD in comparison with donepezil. Methods: The retrieval period of seven databases was from the establishment of each database to April 2019. Two authors independently identified randomized controlled trials (RCTs), fetched data and assessed bias risk. Comprehensive analysis process was conducted with review manager for eligible and appropriate RCTs. Results: A complete of 981 AD patients from 13 studies were enclosed. Meta-analysis of RCTs showed that there was no significant difference in the improvement of Alzheimer's disease assessment scale-cognitive subscale score between 2 groups in short term, but the effect of long-term treatment may exceed donepezil; there was a significant difference in the improvement of activities of daily living score between 2 groups; there was a significant difference in TCM curative efficacy between 2 groups with long-term treatment. There was no significant difference in the incidence of adverse events between 2 groups. The quality of the evidence was high or moderate. Conclusion: Compared with donepezil, TKNF was an effective drug for AD patients and the clinical application of TKNF was safe. TKNF's long-term benefits need more evidence to verify.
Practical guide to evaluation and treatment of obesity overweight for physici...Prab Tumpati
This is an excellent guide from NIH to anybody interested in learning about obesity, overweight and strategies to fight obesity.
Please feel free to share this free, public domain information
Thank you.
W8MD Medical Weight Loss Centers
Palliative care is about providing well-being and the highest quality of life to patients with serious, progressive, chronic life-limiting illness, including during the dying process.
Carle Palliative Care Journal Club for 7/3/18Mike Aref
Journal club review of "Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial" by D. Hui et. al. in JAMA. 2017 Sep 19;318(11):1047-1056.
The goal of this webinar was to help hospice and healthcare professionals understand the history, philosophy, and practice of hospice and palliative care.
Efficacy and safety of traditional Chinese medicine kidney-nourishing formula...LucyPi1
Abstract Objective: Finding an effective therapy against Alzheimer’s disease (AD) has been associate increasingly pressing issue and traditional Chinese medicine (TCM) is widespread in the prevention and treatment of AD in China. The aim of this study was to judge the efficaciousness and safety of TCM kidney-nourishing (the changes of pathological state of kidney deficiency by means of TCM treatment and so on) formula (TKNF) for AD in comparison with donepezil. Methods: The retrieval period of seven databases was from the establishment of each database to April 2019. Two authors independently identified randomized controlled trials (RCTs), fetched data and assessed bias risk. Comprehensive analysis process was conducted with review manager for eligible and appropriate RCTs. Results: A complete of 981 AD patients from 13 studies were enclosed. Meta-analysis of RCTs showed that there was no significant difference in the improvement of Alzheimer's disease assessment scale-cognitive subscale score between 2 groups in short term, but the effect of long-term treatment may exceed donepezil; there was a significant difference in the improvement of activities of daily living score between 2 groups; there was a significant difference in TCM curative efficacy between 2 groups with long-term treatment. There was no significant difference in the incidence of adverse events between 2 groups. The quality of the evidence was high or moderate. Conclusion: Compared with donepezil, TKNF was an effective drug for AD patients and the clinical application of TKNF was safe. TKNF's long-term benefits need more evidence to verify.
Practical guide to evaluation and treatment of obesity overweight for physici...Prab Tumpati
This is an excellent guide from NIH to anybody interested in learning about obesity, overweight and strategies to fight obesity.
Please feel free to share this free, public domain information
Thank you.
W8MD Medical Weight Loss Centers
Palliative care is about providing well-being and the highest quality of life to patients with serious, progressive, chronic life-limiting illness, including during the dying process.
Week 5 EBP ProjectAppraisal of EvidenceCLC EBP Research .docxcockekeshia
Week 5 EBP Project/Appraisal of Evidence
CLC: EBP Research Table
Citation
Include the APA reference note.
Abstract/Purpose
Craft a 100-150 word summary of the research.
Research/Study
Describe the design of the relevant research or study in the article.
Methods
Describe the methods used, including tools, systems, etc.
Setting/Subject
Identify the population and
the setting in which the study was conducted.
Findings/Results
Identify the relevant findings, including any specific data points that may be of interest to your EBP project.
Variables
Describe the independent and dependent variables in the research/study.
Implication for Practice
Articulate the value of the research to the EBP project your group has chosen.
Independent Variable
Dependent Variable
King-Shier, K.M., Mather, C., &LeBlanc, P. (2013). Understanding the influence of urban or rural living on cardiac patients’ decisions about diet and physical activity: Descriptive decision modeling. International Journal of Nursing Studies, 50(11), 1513-1523. doi: 10.1016/j.ijnurstu.2013.03.003
This research aims to answer to better understand the decision-making process of eating a heart healthy diet and extent of physical activity. Also, are these decisions influenced by whether the subject lives in a rural or urban setting. The research proposal was the cultural issues effected participants decision making as well as place of residence. This research used a previous qualitative research design in which 42 cardiac patients (21 urban, and 21 rural) were interviewed about their diet and physical activity. The researchers then designed a model for interviewing regarding the decision-making process. The combination model was then given and tested with 647 cardiac patients (327 urban and 320 rural) from Canada. The results were based on 93.5% accuracy for diet and 97.5 % accuracy with physical activity. Results indicated that decision-making was less about place of residence and more about perception of control over health including time, effort, or competing priorities, receipt of appropriate clear information, and appeal of the activity.
A three-staged, multi-methods approach was used to develop and analyze the descriptive decision making model that patients use in making decisions regarding their cardiac lifestyle. A cross-sectional survey was used to interview patients one year post-cardiac catherization. These interviews were performed via telephone. A three stage decision tree model was then used to analyze the information offered. The stages were as follows: 1. Factors that were influential in decision making. 2. If and where failure had occurred for patients. 3. Did patients consistently, sometimes, or not at all engage in physical activity and a heart healthy diet. Results were then analyzed using statistical analysis.
Information was gathered from a previous series of qualitative interviews conducted with 42 cardiac patients (21 rural, 21 urban). Based on the infor.
Telaah jurnal Prevalence of hypochondriac symptoms among health science stude...Rindang Abas
Hypochondriac symptoms are commonly reported in health science students. With their incomplete medical knowledge, they may compare their own bodily symptoms with disease symptoms during the process of learning, which can lead to mental distress and the need for repeated medical reassurance.
Lipid Screening in Childhood for Detection of Multifactorial DyslipidemiaGlobal Medical Cures™
Lipid Screening in Childhood for Detection of Multifactorial Dyslipidemia
IMPORTANT NOTE TO USERS OF WEBSITE & DOCUMENTS POSTED ON SLIDESHARE- Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
www.globalmedicalcures.com
Hepatitis C Risk Assessment, Testing and Referral for Treatment in primary Ca...Real Wellness, LLC
Dr. Robert Winn worked with a team to determine rates of hepatitis C (HCV) risk factor ascertainment, testing, and referral in urban primary care practices, with particular attention to the effect of race and ethnicity.
To evaluate the benefits of Structured Medication Reviews in elderly Chinese ...Health Innovation Wessex
The Health Innovation Network Polypharmacy programme is working with healthcare professionals to address problematic polypharmacy by supporting easier identification of patients at potential risk from harm from multiple medications.
Our evidence-based polypharmacy Action Learning Sets (ALS) are being rolled out across England to support GPs, pharmacists and other healthcare professionals who undertake prescribing or medication reviews to understand the complex issues around stopping inappropriate medicines safely.
To drive and accelerate changes in practice, delegates complete a quality improvement project to address problematic polypharmacy in their workplace. This poster summary, To evaluate the benefits of Structured Medication Reviews in elderly Chinese patients, can be viewed here.
For more information about the polypharmacy programme, please visit https://thehealthinnovationnetwork.co.uk/programmes/medicines/polypharmacy/
Running Head QUANTITATIVE RESEARCH SUMMARY1QUANTITATIVE RESE.docxtodd581
Running Head: QUANTITATIVE RESEARCH SUMMARY 1
QUANTITATIVE RESEARCH SUMMARY 10
QUANTITATIVE RESEARCH SUMMARY
Student’s Name: Letzy Reyes
Institution: Grand Cayon University
Date: 06/10/2018
Nursing Practice Problem
P-(Problem) – elderly patients aged above 50 years admitted in hospital and having shown blood pressure disease signs. Patients not included in the research were pregnant women.
I-(Intervention) – the patients who are subject in this research will be subjected to therapeutic routine concerning hypertension. The blood pressure of all the patients was tested after administering hypertension medicine to the subjects. The resultant changes were recorded every day to determine the reaction and thus the group will make a conclusion.
C-(Comparison) – institutionalized quality methods will be regulated for hypertension and subjected to the group. The comparison between the groups will be done towards the end of the month in the group.
O-(Outcome) - there will be good relation between the hypertension medication and blood pressure.
T-(Time) – for the next one month the blood pressure will be monitored closely.
The nursing practice portion should be in paragraph form.
PICOT Statement
Elderly patients under hypertension medication together with pharmacological interventions can be maintained in hospitals to improve their blood pressure and with understanding the background and culture of the patients will be of great help in dealing with hypertension. Comment by Doreen Farley: Letzy, I know that this is not the PICOT question that we decided on. What happened to the PICOT?
In patients with hypertension, does the use of meditation along with pharmacological interventions compared to medications alone improve blood pressure? This was the PICOT from out last discussion on 6-1-18
This paper is supposed to be double space only. I am not sure why there is so much space in between concepts.
Introduction
Background of the study
The purpose of the study was to evaluate analyze how patients using hypertension medication along with pharmacological interventions compared to medications alone improve blood pressure. The bottom line of the study was to evaluate how different opinions on hypertension and the treatment of the disease and how such opinions differ from one place to another especially due to the difference in culture or ethnicity of these groups. In addition, the study will be evaluated on what the proposed interventions would do to improve the adherence to these groups. Comment by Doreen Farley: The study evaluated…
The proposed interventions from the research on the two articles will be of importance to the nursing field. There is the need for the nurses to connect, care and convey treatment for various groups of patients in our diverse community. These include taking treatment to patients from different ethnic and racial groups. When it comes to hypertension, nurses have been faced with challenges .
Journal Article Analysis: Medication Errors in Overweight and Obese Pediatric...Paul Pasco
A journal article analysis ("journal club") I completed during an internship/Advanced Pharmacy Practice Experience (APPE) in medication safety at a hospital.
Background:
Heart failure is a major public health problem, and self-management is the primary approach to control the progression of heart failure. The low research participation rate among rural patients hinders the generation of new evidence for improving self-management in rural heart failure patients.
Purpose:
The purpose of this study is to identify the barriers and strategies in the recruitment and retention of rural heart failure patients in behavioral intervention programs to promote self-management adherence.
Method:
This is a descriptive study using data generated from a randomized controlled trial.
Results:
Eleven common barriers were identified such as the inability to perceive the benefits of the study, the burden of managing multiple comorbidities, and the lack of transportation to appointments. Possible gateways to improve recruitment and retention include using recruiters from the local community and promoting provider engagement with research activities. Multiple challenges inhibited rural heart failure patients from participating in and completing the behavioral intervention study.
Conclusion and implications:
Anticipation of those barriers, and identifying strategies to remove those barriers, could contribute to an improvement in the rural patients’ participation and completion rates, leading to the generation of new evidence and better generalizability of the evidence.
Determine the Patients' Satisfaction Concerning In-hospital Information Progr...iosrjce
IOSR Journal of Nursing and health Science is ambitious to disseminate information and experience in education, practice and investigation between medicine, nursing and all the sciences involved in health care.
Nursing & Health Sciences focuses on the international exchange of knowledge in nursing and health sciences. The journal publishes peer-reviewed papers on original research, education and clinical practice.
By encouraging scholars from around the world to share their knowledge and expertise, the journal aims to provide the reader with a deeper understanding of the lived experience of nursing and health sciences and the opportunity to enrich their own area of practice
Works Cited Milne, Anne C., Alison Avenell, and Jan Potter. Meta-.docxkeilenettie
Works Cited
Milne, Anne C., Alison Avenell, and Jan Potter. "Meta-Analysis: Protein and Energy Supplementation in Older People."
Annals of Internal Medicine
144.1 (2006): 37-48.
ProQuest.
Web. 1 Oct. 2014.
Meta-Analysis: Protein and Energy Supplementation in Older People Anne C. Milne, MSc; Alison Avenell, MD; and Jan Potter, MBChB Background: Protein and energy undernutrition is common in older people, and further deterioration may occur during illness. Purpose: To assess whether oral protein and energy supplementa tion improves clinical and
nutritional outcomes for older people in the hospital, in an institution, or in the community. Data Sources: Cochrane Central Register of Controlled Trials (CEN TRAL), MEDLINE, EMBASE,
HealthStar, CINAHL, BIOSIS, and CAB abstracts. The authors included English- and non-English-language studies and hand-searched journals, contacted manufacturers, and sought information from trialists. The date of the most recent search of CENTRAL and MEDLINE is June 2005. Study Selection: Randomized and quasi-randomized controlled tri als of oral protein and energy
supplementation compared with placebo or control treatment in older people. Data Extraction: Two reviewers independently assessed trials for inclusion, extracted data, and assessed trial quality. Differences were resolved by consensus. Data Synthesis: Fifty-five trials were included (n = 9187 randomly tions (Peto odds ratio, 0.72 [95% Cl, 0.53 to 0.97]) and reduced mortality (Peto odds ratio, 0.66 [CI, 0.49 to 0.90]) for those un dernourished at baseline. Few studies reported evidence that suggested any change in mortality, morbidity, or function for those given supplements at home. Ten trials reported gastrointestinal disturbances, such as nausea, vomiting, and diarrhea, with oral supplements. Limitations: The quality of most studies, as reported, was poor, particularly for concealment of allocation and blinding of outcome assessors. Many studies were too small or the follow-up time was too short to detect a statistically significant change in clinical out come. The clinical results are dominated by 1 very large recent trial in patients with stroke. Although this was a high-quality trial, few participants were undernourished at baseline. Conclusions: Oral nutritional supplements can improve nutritional status and seem to reduce mortality and complications for under nourished elderly patients in the hospital. Current evidence does not support routine supplementation for older people at home or for well-nourished older patients in any setting. assigned participants). For patients in short-term care hospitals who were given oral supplements, evidence suggested fewer complica-Ann Intern Med. 2006:144:37-48. For author affiliations, see end of text.
www.annals.OIJ
ndernutrition among older people is a continuing source of concern (1, 2). Older people have longer periods of illness and longer hospital stays (3), and data show tha.
Auditing Medication errors in hospitalised patients at Chiradzulu and QECH Ho...Samson Rangford Chilambe
A proposal for Pharmacy year undergraduate research study for Samson Chilambe and Frank Chadewa. The proposal was approved by the COMREC hence the study was conducted at a small scale level in . Should funding be there, it shall be conducted at larger scale.
1. ORIGINAL ARTICLE
A Comparative Study of Liver Disease Care in the USA
and Urban and Rural China
Ming Yang1 • Elizabeth Wu2 • Huiying Rao1 • Fanny H. Du3 • Angela Xie2 •
Shanna Cheng2 • Cassandra Rodd2 • Andy Lin4 • Lai Wei1 • Anna S. Lok2,5
Received: 28 February 2016 / Accepted: 17 May 2016 / Published online: 2 June 2016
Ó Springer Science+Business Media New York 2016
Abstract
Background Chronic liver disease is a major cause of
morbidity and mortality in the USA and China, but the
etiology of liver disease, medical practice, and patient
expectations in these two countries are different.
Aims To compare patient knowledge about their liver
disease, patient satisfaction with liver disease care, and
patient medical decision-making preference in the USA
and China.
Methods Three cohorts of established adult patients with
liver disease seen in liver clinics in Ann Arbor, USA, and
Beijing (urban) and Hebei (rural), China, completed a
survey between May and September 2014.
Results A total of 990 patients (395 USA, 398 Beijing, and
197 Hebei) were analyzed. Mean liver disease knowledge
score (maximum 5) in the USA, Beijing, and Hebei
patients was 4.1, 3.6, and 3.0, respectively (p 0.001). US
patients had a greater preference for collaborative decision-
making: 71.8 % preferred to make treatment decisions
together with the doctor, while most Chinese patients
(74.6 % Beijing and 84.8 % Hebei) preferred passive
decision-making. Mean satisfaction score (maximum 85) in
the USA was higher than in Beijing, which in turn was
higher than in Hebei (78.2 vs. 66.5 vs. 60.3, p 0.001).
There was a positive correlation between liver disease
knowledge score and satisfaction score (r = 0.27,
p 0.001) and with collaborative medical decision-mak-
ing (r = 0.22, p 0.001) when responses from all sites
were combined.
Conclusions Liver disease knowledge and patient satis-
faction were greatest in the USA, followed by Beijing and
& Anna S. Lok
aslok@med.umich.edu
Ming Yang
ymicecream@163.com
Elizabeth Wu
elizwu@med.umich.edu
Huiying Rao
raohuiying@pkuph.edu.cn
Fanny H. Du
fannydu@med.umich.edu
Angela Xie
axie@med.umich.edu
Shanna Cheng
shanna.cheng@gmail.com
Cassandra Rodd
calyrodd@umich.edu
Andy Lin
andylin@umich.edu
Lai Wei
weilai@pkuph.edu.cn
1
Hepatology Institute, Peking University People’s Hospital,
Peking University Health Science Center, 11 South Xizhimen
St, Beijing 100044, China
2
Division of Gastroenterology and Hepatology, University of
Michigan Health System, 1150 W Medical Center Drive,
4321 Med Sci I, Ann Arbor, MI 48109, USA
3
University of Michigan Medical School, 1301 Catherine
Street, Ann Arbor, MI 48109, USA
4
The Molecular and Behavioral Neuroscience Institute,
University of Michigan, 205 Zina Pitcher Pl, Ann Arbor,
MI 48109, USA
5
University of Michigan Health System, 1500 E Medical
Center Drive, 3912 Taubman Center, SPC 5362, Ann Arbor,
MI 48109, USA
123
Dig Dis Sci (2016) 61:2847–2856
DOI 10.1007/s10620-016-4206-2
2. then Hebei patients. Understanding these differences and
associated factors may help to improve patient outcomes.
Keywords Knowledge gaps Á Healthcare delivery Á
Hepatitis Á Cultural differences Á Medical decision-making
Introduction
Chronic liver disease is a major cause of morbidity and
mortality in both the USA and China. It is estimated that
approximately 15 % of the US population and 28 % of the
Chinese population has chronic liver disease, but the eti-
ology of liver disease, medical practice, and patient
expectations in these two countries are different [1–3].
Nonalcoholic fatty liver disease (NAFLD), hepatitis C
virus (HCV), and alcoholic liver disease (ALD) account for
the majority of liver diseases in the USA, while hepatitis B
virus (HBV), NAFLD, and ALD are the most common
liver diseases in China [2, 3].
Many studies have shown that patient satisfaction with
their care is associated with increased adherence and
improved outcomes [4–6]. Patient satisfaction is an
important metric of quality of care in Western countries
[7–9], but until recently has received little attention in
China [10, 11]. Most studies on patient satisfaction have
focused on satisfaction with cancer or pain care
[5, 12, 13], and rarely on liver disease care [14]. Patient
knowledge about their illness has been reported to cor-
relate with satisfaction with care and to influence uptake
of treatment, adherence, and outcomes [15]. Studies of
patients with HBV and HCV showed increasing patients’
knowledge increased uptake of screening and treatment as
well as compliance with treatment [15–17], but data on
knowledge gaps in other types of liver diseases are lim-
ited. Evidence suggests that a patient-centered approach
to healthcare management improves a patient’s overall
satisfaction with care and may lead to reduced associated
symptoms [18]. Shared decision-making has gained
attention in the medical field over the last decade [19]. In
many countries, such as the USA, shared decision-making
is the norm; but in some countries, such as China, med-
ical practice remains largely paternalistic and physicians
make most of the decisions.
Given the huge burden of chronic liver disease in both
the USA and China and the differences in culture and
medical practice, we conducted this study to compare US
and Chinese patients’ knowledge of their liver disease,
satisfaction with liver disease care, and medical decision-
making preferences, and to determine the factors associated
with patients’ satisfaction with liver disease care.
Materials and Methods
Subject Recruitment
Consecutive established patients with liver diseases seen in
liver clinics at a tertiary hospital in Ann Arbor, Michigan,
USA; an urban tertiary hospital in Beijing, China; and a
rural community hospital in Hebei Province, China, were
invited to participate in a survey study between May and
September 2014. The site in Hebei Province is 150 miles
away from Beijing, and most residents there are farmers
with limited education. The liver clinic in the USA is
hospital based, and providers include 10 hepatology faculty
and 4 mid-level providers, plus rotating fellows, residents
and students, and appointments are required. The liver
clinic in Beijing is tertiary hospital based, and providers
include 16 hepatology faculty and a few students. The liver
clinic in Hebei is community hospital based, and providers
only include 4 hepatology faculty. Appointments are not
necessary in the two Chinese sites. Average time for a
return clinic visit in these three sites is 20, 5, and 5 min,
respectively.
Adults (C18 years) with a known diagnosis of liver
disease, who had at least two prior visits to the same clinic,
were included. Patients were approached during their clinic
visit, and verbal informed consent was obtained. Patients
could choose to self-administer the survey or have a trained
researcher read the questions verbatim and record the
answers for them.
The study was reviewed and approved by the Institu-
tional Review Boards of both the University of Michigan
and Peking University.
Survey Design
The survey consisted of four sections: (1) knowledge about
their liver disease, (2) preferences in medical decision-
making, (3) satisfaction with their liver care, and (4)
demographics. In the patient knowledge section, we had
one question on patients’ self-assessment of their knowl-
edge and five questions about general knowledge of liver
diseases: The liver disease you have ‘‘is infectious,’’ ‘‘is
inherited,’’ ‘‘can cause cirrhosis,’’ ‘‘can cause liver can-
cer,’’ and ‘‘can be prevented by vaccination.’’ In the
medical decision-making section, one key question asked
patients whether they preferred medical decisions to be
made by ‘‘the doctor entirely,’’ ‘‘the doctor, considering my
preferences,’’ ‘‘me and the doctor together,’’ ‘‘me, consid-
ering input from the doctor,’’ or ‘‘me entirely.’’ For patient
satisfaction, although one questionnaire had been used to
assess patient satisfaction with liver disease care, it was
2848 Dig Dis Sci (2016) 61:2847–2856
123
3. studied in only 152 patients in the Netherlands and has not
been externally validated [14]. We chose to use a ques-
tionnaire developed by the National Cancer Institute
(NCI)-sponsored Patient Navigation Research Program
because it has been used in many studies on patients of
diverse racial/ethnic background [12, 20, 21]. The NCI
questionnaire included 18 items measured on a five-point
Likert scale ranging from ‘‘Definitely No’’ to ‘‘Definitely
Yes.’’ We revised the wording in a few items to specify
that we were assessing satisfaction with liver care only. We
deleted the item ‘‘I received high-quality care from my
regular doctor’’ because most patients in China do not have
primary care physicians and added an item ‘‘I will rec-
ommend my liver doctor to friends and family’’ to measure
overall satisfaction with liver care.
The survey was developed in English and then translated
into Chinese by professional translators in China. Accuracy
of the translation was verified by two native Chinese-
speaking investigators in the USA. The survey was pilot-
tested in 20 patients in the USA and in Beijing and revised
based on their feedback.
Data Analyses
Data analyses were performed using IBM SPSS Statistics
(SPSS, version 21). Patients were excluded from the
analyses if the demographics section was incomplete.
Descriptive statistics were used to describe the patient
populations and their responses. For comparisons of
knowledge, we assigned scores of 0 for incorrect or ‘‘don’t
know’’ responses and 1 for correct responses to each of the
five knowledge questions. An overall knowledge score
(maximum 5) was computed by adding the scores of the 5
items. We tested the validity of the NCI questionnaire on
patient satisfaction by exploratory factor analysis for latent
structure and its internal consistency by Cronbach coeffi-
cient alpha (a). We found a 1-dimensional measure with 17
of 18 items in the questionnaire forming a coherent set
explaining 71.8 % of the variance in patient satisfaction in
the USA, 65.3 % in Beijing, and 67.9 % in Hebei. In
subsequent analyses, we removed the outlier item ‘‘My
regular doctor (primary care doctor or family doctor) was
informed about the results of the tests I got for my liver
disease.’’ Reliability assessment revealed that the remain-
ing questionnaire had high internal consistency (0.97 in the
USA, 0.94 in Beijing, and 0.95 in Hebei). We assigned
scores of 1–5 for responses to each item in the question-
naire with a score of 1 for a response of ‘‘Definitely No’’
and a score of 5 for a response of ‘‘Definitely Yes.’’ An
overall satisfaction score (maximum 85) was computed by
adding the scores of the 17 validated items.
Comparison between groups was performed using Chi-
squared test for categorical data and ANOVA test or
nonparametric test for numerical data. Pearson’s correla-
tion was used for correlation of parametric data and
Spearman’s correlation coefficient for nonparametric data.
General linear model was used to evaluate factors inde-
pendently associated with patient satisfaction with liver
disease care. Exploratory independent variables included
study site, sex, age, education, type of liver disease (HBV,
HCV, or others), duration of liver disease diagnosis,
duration of follow-up at the liver clinic, patients’ assess-
ment of their knowledge, liver disease knowledge score,
and preference for medical decision-making. p val-
ues 0.05 were considered statistically significant.
Results
A total of 1019 patients (413 USA, 406 Beijing, and 200
Hebei) participated. Twenty-nine patients (18 USA, 8
Beijing, and 3 Hebei) were excluded because responses to
questions on demographics were incomplete, and 990
patients (395 USA, 398 Beijing, and 197 Hebei) were
included in the analyses.
Characteristics of Patients Analyzed
Demographics and diagnoses of the patients are shown in
Table 1. More than half the patients were male: 67.5 % in
Hebei, 62.6 % in Beijing, and 53.2 % in the USA
(p = 0.001). Mean ages of US, Beijing, and Hebei patients
were 55.2, 53.0, and 49.0 years, respectively (p 0.001).
Beijing patients were most likely to have college or post-
graduate education, followed by US patients, while few
Hebei patients had higher education (67.3 % Beijing vs.
57.7 % USA vs. 7.1 % Hebei, p 0.001). US patients
were predominantly white (80.0 %); almost all (94.0 %)
Beijing, but only 33.0 % Hebei patients were Han Chinese.
Most common liver diseases in the USA were HCV
(43.5 %), autoimmune liver diseases (16.5 %), and
NAFLD (10.9 %), while the most common liver diseases in
Beijing and Hebei were HBV (67.8 and 49.2 %) and HCV
(14.8 and 42.2 %). Beijing and US patients had been
diagnosed with their liver disease (p 0.001) and followed
up in the liver clinic (p 0.001) longer than those in
Hebei.
Liver Disease Knowledge and Medical Decision-
Making
A higher percentage of US (69.9 %) and Beijing (51.3 %)
patients reported knowing ‘‘a fair amount’’ or ‘‘a lot’’ about
their liver disease compared to Hebei (31.3 %) patients
(p 0.001). Mean knowledge scores (maximum 5) for all
Dig Dis Sci (2016) 61:2847–2856 2849
123
4. sites combined was 3.7 ± 1.2. US patients scored the
highest (4.1 ± 0.9), followed by Beijing (3.6 ± 1.1) and
then Hebei patients (3.0 ± 1.4) (p 0.001).
Most (71.8 %) US patients preferred collaborative
decisions with physicians, while Chinese patients (74.6 %
Beijing and 84.8 % Hebei) preferred physicians to make
medical decisions entirely or with their input (Table 2).
There was a positive correlation between liver disease
knowledge score and collaborative medical decision-mak-
ing (r = 0.22, p 0.001) when responses from all sites
were combined.
Patient Satisfaction with Liver Disease Care
Patient responses to the 17 items that measured satisfaction
with liver disease care at the three sites are shown in Fig. 1.
US patients were significantly more satisfied with their
liver care than the Chinese patients in all 17 items with
62.5–87.8 % US patients compared to 29.9–52.8 % Beijing
patients and 10.2–56.9 % Hebei patients selecting ‘‘Defi-
nitely Yes’’ in response to each item.
The average scores for each of the 17 items (maximum
5) ranged from 4.3 to 4.8 in US patients, 3.6 to 4.3 in
Beijing patients, and 2.5 to 4.4 in Hebei patients (Table 3).
Among the 17 items, the item ‘‘I felt that I was treated with
courtesy and respect’’ scored well for all three sites with
mean scores of 4.8, 4.3, and 4.0 in the USA, Beijing, and
Hebei, respectively, while the item ‘‘I knew what the next
step in the care of my liver disease would be’’ had a low
score for all three sites with mean scores of 4.3, 3.8, and
2.8 in the USA, Beijing, and Hebei, respectively. The item
‘‘I felt included in decisions about my health’’ showed the
Table 1 Characteristics of patients by study site
USA Beijing Hebei p value
Total 395 398 197
Sex, men [n (%)] 210 (53.2) 249 (62.6) 133 (67.5) 0.001
Mean age (SD) (year) 55.2 (12.1) 53.0 (14.4) 49.0 (11.5) 0.001
Race/ethnicity [n (%)]
White 316 (80.0) Han 374 (94.0) Han 65 (33.0)
African-American 31 (7.8) Non-Han 23 (5.7) Non-Han 132 (67.0)
Other 48 (12.2) Other 1 (0.3) Other 0 (0.0)
Education level [n (%)] 0.001
High school or less 167 (42.3) 130 (32.7) 183 (92.9)
College/university 163 (41.3) 217 (54.5) 14 (7.1)
Graduate/professional school 65 (16.4) 51 (12.8) 0 (0.0)
Liver disease type [n (%)] 0.001
Hepatitis B 28 (7.1) 270 (67.8) 97 (49.2)
Hepatitis C 172 (43.5) 59 (14.8) 83 (42.2)
Alcoholic liver disease 27 (6.8) 8 (2.0) 8 (4.1)
Nonalcoholic fatty liver disease 43 (10.9) 11 (2.8) 5 (2.5)
Drug-induced liver injury 7 (1.8) 11 (2.8) 2 (1.0)
Autoimmune liver disease 65 (16.5) 27 (6.8) 1 (0.5)
Inherited metabolic liver disease 15 (3.8) 0 (0.0) 1 (0.5)
Other or unknown 38 (9.6) 12 (3.0) 0 (0.0)
Duration of diagnosis of liver disease [n (%)] 0.001
Less than 1 year ago 14 (3.5) 42 (10.6) 41 (20.8)
1–5 years ago 138 (34.9) 71 (17.8) 71 (36.0)
5–10 years ago 91 (23.1) 50 (12.6) 36 (18.3)
More than 10 years ago 152 (38.5) 235 (59.0) 49 (24.9)
Duration of follow-up at liver clinic [n (%)] 0.001
Less than 1 year 33 (8.4) 81 (20.4) 71 (36.0)
1–2 years 87 (22.1) 60 (15.1) 38 (19.3)
2–5 years 115 (29.2) 85 (21.3) 58 (29.5)
5–10 years 89 (22.6) 73 (18.3) 16 (8.1)
More than 10 years 70 (17.7) 99 (24.9) 14 (7.1)
SD standard deviation
2850 Dig Dis Sci (2016) 61:2847–2856
123
5. biggest difference in responses across the three sites with
mean scores of 4.7, 3.9, and 2.5 in the USA, Beijing, and
Hebei, respectively. The mean overall satisfaction score
(maximum = 85) for all 17 items was significantly higher
for US patients than for Beijing patients, which in turn was
higher than in Hebei patients (78.2 vs. 66.5 vs. 60.3,
p 0.001).
Factors Associated with Patient Satisfaction
with Liver Disease Care
When responses from all three sites were combined, there
was a positive correlation between liver disease knowledge
score and satisfaction score (r = 0.27, p 0.001). General
linear model showed that study site, patients’ assessment of
their knowledge, and liver disease knowledge score were
significant predictors of patient satisfaction with liver dis-
ease care. When responses were analyzed by site, age was
the only significant predictor of patient satisfaction with
liver disease care in US patients, while patients’ assessment
of their knowledge and liver disease knowledge score were
significant predictors in Beijing patients. Age, patients’
assessment of their knowledge, and liver disease knowl-
edge score were significant predictors in Hebei patients
(Table 4).
Discussion
In this survey of almost 1000 patients with chronic liver
disease, patient knowledge of their liver disease and sat-
isfaction with liver care in the USA were better than in
urban China, which in turn was better than in rural China.
As far as we know, our study is the first to comprehensively
assess patient satisfaction with liver disease care and to
compare patient satisfaction in the USA and China. Our
patient satisfaction questions, adapted from Jean-Pierre’s
Patient Satisfaction with Cancer Care, were shown to be
highly reliable and internally consistent.
Multiple factors contribute to patient satisfaction,
including patient factors (knowledge about their disease,
expectations, education), provider factors (attitude, time
spent educating patients and explaining diagnosis and care
plans, knowledge and experience), and system factors (ease
of scheduling clinic appointments, time available for each
clinic visit, availability of ancillary staff such as nurses to
facilitate care and communications, clinic environment)
[22]. Understanding which aspect of care patients are least
satisfied with and the factors associated with patient dis-
satisfaction can provide insights into interventions that will
improve patient satisfaction and ultimately patient
outcomes.
Table 2 Patient knowledge
about their liver disease and
medical decision-making
preference by study site
USA Beijing Hebei p value
Patients’ assessment of their knowledge [n (%)] 0.001
Nothing 14 (3.5) 11 (2.8) 23 (11.7)
A little bit 105 (26.6) 183 (46.0) 112 (57.1)
A fair amount 191 (48.4) 173 (43.5) 52 (26.5)
A lot 85 (21.5) 31 (7.8) 9 (4.6)
Liver disease knowledge score, mean (SD)
Overall 4.1 (0.9) 3.6 1.1) 3.0 (1.4) 0.001
Hepatitis B 3.8 (1.1) 3.6 (1.1) 3.0 (1.3) 0.001
Hepatitis C 4.3 (0.9) 3.5 (1.3) 3.0 (1.4) 0.001
Alcoholic liver disease 4.2 (0.7) 3.6 (0.9) 3.9 (1.1) 0.26
Nonalcoholic fatty liver disease 3.8 (1.0) 3.4 (0.9) 3.6 (1.5) 0.51
Drug-induced liver injury 4.1 (0.7) 3.0 (1.0) 1.5 (2.1) 0.01
Autoimmune liver disease 4.0 (1.0) 3.9 (0.8) 2.0 (0.0) 0.09
Inherited metabolic liver disease 4.3 (0.6) NA 0.0 (0.0) 0.001
Medical decision-making [n (%)] 0.001
By the doctor entirely 33 (8.4) 151 (37.9) 89 (45.2)
By the doctor, considering my preferences 43 (10.9) 146 (36.7) 78 (39.6)
By me and the doctor together 282 (71.8) 89 (22.4) 23 (11.7)
By me, considering input from the doctor 34 (8.7) 11 (2.8) 6 (3.0)
By me entirely 1 (0.3) 1 (0.3) 1 (0.5)
SD standard deviation, NA not applicable
Dig Dis Sci (2016) 61:2847–2856 2851
123
6. Regarding patient factors, our study showed that patient
knowledge correlated with patient satisfaction. Self-
assessment of liver disease knowledge showed that US
patients were more likely to report greater knowledge than
Chinese patients. While this difference may be related to
cultural differences with Chinese culture placing a greater
emphasis on humility and the US culture on self-confi-
dence, the self-assessment by patients correlated with their
Fig. 1 Patient responses to the
17 items that measured
satisfaction with liver disease
care at the three study sites:
a the USA, n = 395; b Beijing,
n = 398; c Hebei, n = 197
2852 Dig Dis Sci (2016) 61:2847–2856
123
7. Table 3 Average scores of responses to patient satisfaction questions by study site
USA Beijing Hebei
(a) I felt that my health concerns were understood 4.7 3.9 3.8
(b) I felt that I was treated with courtesy and respect 4.8 4.3 4.0
(c) I felt included in decisions about my health 4.7 3.9 2.5
(d) I was told how to take care of my liver disease 4.5 4.3 3.9
(e) I felt encouraged to talk about my personal health concerns 4.6 3.8 3.4
(f) I felt I had enough time with my doctor 4.5 3.7 3.6
(g) My questions were answered to my satisfaction 4.6 4.2 3.8
(h) Making an appointment was easy 4.6 3.9 4.4
(i) I knew what the next step in the care of my liver disease would be 4.3 3.8 2.8
(j) I feel confident in how I deal with the liver team 4.5 3.6 3.6
(k) I was able to get the advice I needed about my health issues 4.6 4.0 3.7
(l) I knew who to contact when I had a question 4.5 3.9 3.8
(m) I received all the services I needed 4.6 3.9 3.3
(n) I am satisfied with the care I received 4.7 4.2 3.6
(o) Members of the liver team (doctors, nurses, physician assistants, etc.) seemed to communicate well about my care 4.6 3.8 2.8
(p) I received high-quality care from my liver team 4.7 3.7 3.5
(q) I will recommend my liver doctor to friends and family 4.7 3.6 3.8
Mean overall satisfaction scorea,b,c,d
78.2 66.5 60.3
Comparisons of mean overall satisfaction score a
among three sites, b
between USA and Beijing, c
between USA and Hebei, d
between Beijing
and Hebei, all p 0.001
We removed the outlier item ‘‘My regular doctor (primary care doctor or family doctor) was informed about the results of the tests I got for my
liver disease’’
Table 4 Factors associated with patient satisfaction with liver disease care
Cohort Variable Coefficient 95 % CI p value
Three cohorts
combined
Site (vs. Hebei)
USA 14.3 11.2 to 17.4 0.001
Beijing 5.3 2.7 to 7.9 0.001
Patients’ assessment of their knowledge (a fair amount and a lot vs. nothing and a
little bit)
3.4 1.5 to 5.3 0.001
Liver disease knowledge scorea
1.5 0.7 to 2.2 0.001
USA Ageb
0.2 0.1 to 0.3 0.002
Beijing Patients’ assessment of their knowledge (a fair amount and a lot vs. nothing and a
little bit)
4.8 1.9 to 7.7 0.001
Liver disease knowledge score 1.4 0.2 to 2.6 0.019
Hebei Age -0.3 -0.4 to
-0.1
0.003
Patients’ assessment of their knowledge (a fair amount and a lot vs. nothing and a
little bit)
5.9 1.5 to 10.2 0.009
Liver disease knowledge score 2.0 0.4 to 3.5 0.012
CI confidence Interval
a
Coefficient for liver disease knowledge score is difference of patient satisfaction score by 1 liver disease knowledge score
b
Coefficient for age is difference of patient satisfaction score by 1 year
Dig Dis Sci (2016) 61:2847–2856 2853
123
8. knowledge score. Higher knowledge scores have been
reported to be associated with greater satisfaction with care
[23–25]. Our data suggest that improving patients’ under-
standing of their disease could improve their satisfaction
with care. Increased knowledge about one’s disease might
help patients understand what symptoms and outcomes to
expect, what treatment options are available, and how
effective they are. Setting realistic expectations might
decrease frustrations and disappointment particularly when
the outcomes are unfavorable. In our study, age was a
predictor of patient satisfaction in the USA and Hebei.
Most previous studies found that older age was signifi-
cantly associated with higher satisfaction scores [26, 27].
We found the same trend in US patients, but the opposite
trend in Hebei patients. The reason for the difference in
Hebei might be the older patients there had lower education
level and poorer communication with physicians. We
found that sex and education were not predictors of patient
satisfaction. A meta-analysis also found that the effects of
gender and education on patient satisfaction were mixed
[28]. We had hypothesized that patients with different liver
diseases might differ in their satisfaction with care, but this
was not the case when results were analyzed by site and
combined.
Regarding provider factors, our study showed all three
sites scored well on the item ‘‘I felt that I was treated with
courtesy and respect.’’ Treating patients with respect and
empathy is a fundamental component of medical educa-
tion, but with increasing technological advances in medi-
cine, time spent on training physicians on humanities and
art of medicine may be eroded. Traditionally, the practice
of medicine in China tended to be paternalistic. It is reas-
suring to see that a high percent of patients at the two
Chinese sites felt they were treated with courtesy and
respect. Our study indicates that patient dissatisfaction
arose from inadequate or poor communications between
physician and patient. The item ‘‘I knew what the next step
in the care of my liver disease would be’’ had a lower score
for all three sites. Having patients understand the next step
in their care is important, so they can adhere to the care
plan. Communicating to patients using terms that they can
understand and repeating the message in different formats
are important, particularly for patients with less education
and/or limited knowledge about their disease. The item ‘‘I
felt included in decisions about my health’’ showed the
biggest difference in responses across the three sites.
Although many Chinese patients preferred their doctors to
make decisions on their care, many desired to be involved
in the decision as evident by the fact that 36.7 % of Beijing
and 39.6 % of Hebei patients would like their physicians to
consider their preferences in making decisions. Our find-
ings indicate that physicians at all three sites should work
on improving communication of care plans with patients.
Regarding system factors, there are major differences in
how health care is delivered and how clinics are run
between the USA and China. Most Chinese do not have
family doctors or primary care physicians, so they tend to
go to specialty clinics for all their health problems. The
lack of systematic referral systems and the uneven distri-
bution of medical resources in China lead to overcrowding
of patients in large hospitals in China [29]. Furthermore,
most clinics in China do not have appointment systems,
and patients show up similar to walk-in clinics in the USA.
The current healthcare system in China creates multiple
problems which cause patient dissatisfaction: the clinics
are crowded, the physicians cannot plan ahead, and each
patient has limited (often 5 min or less) time with the
physician after waiting in line for hours. In recent years,
China has implemented reforms to the healthcare system.
In 2009, all public tertiary hospitals supported by the
Ministry of Health began to use Web-based appointment
systems, but only a small percent of patients actually use
the system with most patients still choosing walk-in reg-
istration, and clinics in tertiary hospitals continue to see
patients who do not have appointments [30]. The differ-
ences in healthcare delivery systems in the USA and China
must be considered when comparing patient satisfaction in
the two countries. Our study found lower scores on the item
‘‘I felt I had enough time with my doctor’’ at the Chinese
sites. Time constraint may also account for lower scores on
several related items such as ‘‘I felt encouraged to talk
about my personal health concerns’’ at the Chinese sites. In
addition to training physicians to maximize efficiency
during the short time they have with their patients, other
solutions such as use of physician extenders and electronic
communications might supplement the deficiency in face
time with physicians. While mid-level providers and nurses
play an important role in the management of patients with
chronic liver diseases and electronic health records with
patient portals are universal in the USA, these services are
rare in urban China and nonexistent in rural China.
We found a striking difference in patient preference for
medical decision-making between patients in the USA and
those in China with the majority of US patients preferring
collaborative decision-making and the majority of Chinese
patients preferring decisions made by the doctor. Consid-
ering that previous studies have postulated that despite
cultural differences all patients in the USA and China
preferred a collaborative decision-making style [31], it is
interesting that our study challenges this concept and
invokes more insight into cultural relativity. Some studies
have shown that patients who are more knowledgeable
about their disease are more likely to be involved in
deciding how they should be managed [32]. We also found
a correlation between higher knowledge score and prefer-
ence for collaborative decision-making, emphasizing the
2854 Dig Dis Sci (2016) 61:2847–2856
123
9. importance of educating patients so they can actively
participate in making decisions about their care.
Our study provided a comparison of patient knowl-
edge, preference for medical decision-making, and satis-
faction with liver care, not only between patients in the
USA and China, but also between urban and rural China.
Our study site in Hebei is a rural Manchu Autonomous
Region, and the majority of the residents are Manchus
with limited education. We found that patient knowledge
score and satisfaction scores in Hebei were significantly
lower than in Beijing, but preference for medical deci-
sion-making was similar. These differences were not
related to differences in patient ethnicity as all three
measures were similar between Han and non-Han Chinese
in Hebei and more likely a reflection of the gap in edu-
cation, economy, and health infrastructure between rural
and urban China [33].
There were several limitations to this study. First, only
one liver clinic was included in each site, and the study
cohorts may not be fully representative of US and urban
and rural Chinese patients. Second, we were only able to
ask very general knowledge questions since we used the
same questionnaire for all liver diseases. Finally, some
patients completed the survey on their own, while others
had the survey administered by researchers; however,
researchers were trained to read the survey verbatim and
we did not find any systematic differences in responses
between the two administration methods.
In summary, liver disease knowledge and patient satis-
faction were greatest in the USA, followed by Beijing and
then Hebei patients. Improving patients’ understanding of
their disease would improve their satisfaction with care and
their engagement in medical decision-making. Our findings
can be used to design interventions to improve patient
satisfaction of liver disease care and ultimately patient
outcomes.
Acknowledgments Ming Yang was supported by US National
Institutes of Health Research Training Grant 3R25TW009345 awar-
ded to the Northern Pacific Global Health Fellows Program by the
Fogarty International Center and Institutes. Fanny H. Du was sup-
ported by the University of Michigan Medical School Faculty-Led
Global Reach Program for medical students. Angela Xie, Cassandra
Rodd, and Shanna Cheng are undergraduate students supported by the
Alice Lohrman Andrews Research Professorship (to Anna S. Lok).
Lai Wei and Anna S. Lok are supported by grants from the University
of Michigan Health System and Peking University Health Science
Center Joint Institute for Clinical and Translational Research.
Compliance with ethical standards
Conflict of interest Ming Yang, Elizabeth Wu, Huiying Rao, Fanny
H. Du, Angela Xie, Shanna Cheng, Cassandra Rodd, Andy Lin, Lai
Wei, and Anna S. Lok declare that they have no conflict of interest
related to this work.
References
1. Stewart BW, Wild C. International Agency for Research on
Cancer, World Health Organization. World cancer report; 2014.
xiv, 630.
2. Younossi ZM, Stepanova M, Afendy M, et al. Changes in the
prevalence of the most common causes of chronic liver diseases
in the United States from 1988 to 2008. Clin Gastroenterol
Hepatol. 2011;9:524e521–530e521. ; quiz e560..
3. Wang FS, Fan JG, Zhang Z, Gao B, Wang HY. The global burden
of liver disease: the major impact of China. Hepatology.
2014;60:2099–2108.
4. Dang BN, Westbrook RA, Black WC, Rodriguez-Barradas MC,
Giordano TP. Examining the link between patient satisfaction and
adherence to HIV care: a structural equation model. PLoS ONE.
2013;8:e54729.
5. Sanda MG, Dunn RL, Michalski J, et al. Quality of life and
satisfaction with outcome among prostate-cancer survivors. N
Engl J Med. 2008;358:1250–1261.
6. Chow A, Mayer EK, Darzi AW, Athanasiou T. Patient-reported
outcome measures: the importance of patient satisfaction in sur-
gery. Surgery. 2009;146:435–443.
7. Pascoe GC. Patient satisfaction in primary health care: a literature
review and analysis. Eval Program Plan. 1983;6:185–210.
8. Jha AK, Orav EJ, Zheng J, Epstein AM. Patients’ perception of
hospital care in the United States. N Engl J Med. 2008;
359:1921–1931.
9. Pantouvakis A, Bouranta N. Quality and price–impact on patient
satisfaction. Int J Health Care Qual Assur. 2014;27:684–696.
10. Wong EL, Leung MC, Cheung AW, Yam CH, Yeoh EK, Griffiths
S. A population-based survey using PPE-15: relationship of care
aspects to patient satisfaction in Hong Kong. Int J Qual Health
Care. 2011;23:390–396.
11. Yan Z, Wan D, Li L. Patient satisfaction in two Chinese pro-
vinces: rural and urban differences. Int J Qual Health Care. 2011;
23:384–389.
12. Jean-Pierre P, Fiscella K, Freund KM, et al. Structural and reli-
ability analysis of a patient satisfaction with cancer-related care
measure: a multisite patient navigation research program study.
Cancer. 2011;117:854–861.
13. Trentman TL, Cornidez EG, Wilshusen LL, et al. Patient satis-
faction in an academic chronic pain clinic. Pain Pract. 2013;
13:372–379.
14. Gutteling JJ, de Man RA, Busschbach JJ, Darlington AS. Quality
of health care and patient satisfaction in liver disease: the
development and preliminary results of the QUOTE-Liver
questionnaire. BMC Gastroenterol. 2008;8:25.
15. Shah HA, Abu-Amara M. Education provides significant benefits to
patients with hepatitis B virus or hepatitis C virus infection: a sys-
tematic review. Clin Gastroenterol Hepatol. 2013;11:922–933.
16. Gupta K, Romney D, Briggs M, Benker K. Effects of a brief
educational program on knowledge and willingness to accept
treatment among patients with hepatitis C at inner-city hospitals.
J Community Health. 2007;32:221–230.
17. Surjadi M, Torruellas C, Ayala C, Yee HF Jr, Khalili M. Formal
patient education improves patient knowledge of hepatitis C in
vulnerable populations. Dig Dis Sci. 2011;56:213–219.
18. Little P, Everitt H, Williamson I, et al. Observational study of
effect of patient centredness and positive approach on outcomes
of general practice consultations. BMJ. 2001;323:908–911.
19. Joosten EA, DeFuentes-Merillas L, de Weert GH, Sensky T, van
der Staak CP, de Jong CA. Systematic review of the effects of
shared decision-making on patient satisfaction, treatment adher-
ence and health status. Psychother Psychosom. 2008;77:219–226.
Dig Dis Sci (2016) 61:2847–2856 2855
123
10. 20. Jean-Pierre P, Fiscella K, Winters PC, Paskett E, Wells K, Bat-
taglia T. Psychometric validation and reliability analysis of a
Spanish version of the patient satisfaction with cancer-related
care measure: a patient navigation research program study. Sup-
port Care Cancer. 2012;20:1949–1956.
21. Jean-Pierre P, Cheng Y, Paskett E, Shao C, Fiscella K, Winters P.
Item response theory analysis of the patient satisfaction with
cancer-related care measure: a psychometric investigation in a
multicultural sample of 1,296 participants. Support Care Cancer.
2014;22:2229–2240.
22. Crow R, Gage H, Hampson S, et al. The measurement of satis-
faction with healthcare: implications for practice from a sys-
tematic review of the literature. Health Technol Assess. 2002;6:
1–244.
23. Ensor T, Cooper S. Overcoming barriers to health service access:
influencing the demand side. Health Policy Plan. 2004;19:69–79.
24. Marini BL, Funk K, Kraft MD, et al. The effects of an infor-
mational video on patient knowledge, satisfaction and compli-
ance with venous thromboembolism prophylaxis: a pilot study.
Patient Educ Couns. 2014;96:264–267.
25. Nunes JAW, Wallston KA, Eden SK, Shintani AK, Ikizler TA,
Cavanaugh KL. Associations among perceived and objective
disease knowledge and satisfaction with physician communica-
tion in patients with chronic kidney disease. Kidney Int. 2011;
80:1344–1351.
26. Blanchard CG, Labrecque MS, Ruckdeschel JC, Blanchard EB.
Physician behaviors, patient perceptions, and patient character-
istics as predictors of satisfaction of hospitalized adult cancer
patients. Cancer. 1990;65:186–192.
27. Young GJ, Meterko M, Desai KR. Patient satisfaction with hos-
pital care: effects of demographic and institutional characteristics.
Med Care. 2000;38:325–334.
28. Hall JA, Dornan MC. Patient sociodemographic characteristics as
predictors of satisfaction with medical care: a meta-analysis. Soc
Sci Med. 1990;30:811–818.
29. Tang S, Meng Q, Chen L, Bekedam H, Evans T, Whitehead M.
Tackling the challenges to health equity in China. Lancet.
2008;372:1493–1501.
30. Zhang M, Zhang C, Sun Q, Cai Q, Yang H, Zhang Y. Ques-
tionnaire survey about use of an online appointment booking
system in one large tertiary public hospital outpatient service
center in China. BMC Med Inform Decis Mak. 2014;14:49.
31. Bennett K, Smith DH, Irwin H. Preferences for participation in
medical decisions in China. Health Commun. 1999;11:261–284.
32. Say R, Murtagh M, Thomson R. Patients’ preference for
involvement in medical decision making: a narrative review.
Patient Educ Couns. 2006;60:102–114.
33. Dummer TJ, Cook IG. Exploring China’s rural health crisis:
processes and policy implications. Health Policy. 2007;83:1–16.
2856 Dig Dis Sci (2016) 61:2847–2856
123