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SEACOM PHARMACY COLLEGE
Presented by
Arpan Dutta
B.Pharm
1st Year;1st Semester
Reg.No-233830210013
Roll No-38305923013
Antacid
CONTENTS
 Antacid .
 Antacid Compounds.
 Reaction of Antacid .
 ACTION MECHANISM.
 Requirement TO From the Antacid .
 Antacid Are Available As Requirement .
 SOME FAMOUS ANTACID BRANDS .
 Uses of Antacid .
 Who Cannot Take Antacid.
 Conclusion.
 Reference.
ANTACID
 An Antacid is any substance ,generallya base or basic
salt, which neutralizes stomach acidity.theyare used to
relieve acid indigestion ,upset stomach ,sour stomach
,and heartburn.
Antacid Compounds
 Antacids are weak base that are used to neutralize excess
stomach acid.
 Most antacids are weak inorganic bases
 Common examples include
CaCO3
NaHCO3
Al(OH)3
Mg(OH)3
MgO and Mg(OH)3 (Milk of Magnesia)
Reaction of antacid
 Antacids react with HCl in stomach
 Some common antacid reactions include:
 CaCO3+2HCl----CaCl2+H2O+CO2
 NaHCO3+HCl----NaCl+H2O+CO2
 Al(OH)3+3HCl----AlCl3+3H2O
 Mg(OH)2+2 HCl----MgCl2+2H2O
 MgO+2 HCl----MgCl2+H2O
ACTION MECHANISM
 Antacids perform a neutralization reaction ,i.e,they
buffergastric acid ,rasing the pH to reduce acidity in
the stomach, when gastric hydrochloric acid reaches
the nerves in the gastrontestinal mucosa, they signal
pain to the central nervous system .this happenswhen
these nerves are exposed ,as in peptic ulcers. The
gastric acid may also reach ulcers in the esophagusor
the duodenum.
Requirement TO Form Antacid
 Burettes,pipettes,titration flasks,measuring
flasks,beakers,weightbox,fractional weights,sodium
hydroxide,sodiumcarbonate,hydrochloric
acid,phenolphthalein.
Antacid are Available As Requirement
 Capsules.
 Tablets.
 Powder.
 Chewabletablet.
 Suspension.
SOME FAMOUSN ANTACID BRANDS
 1.Alka-Seltzer - NaHCO3 and/orKHCO3
 2.Equate -Al(OH)3 andMg(oh)2
 3.Gaviscon -Al(OH)3
 4.Maalox(liquid) - Al(OH)3 and Mg(OH)2
 5.Maalox(tablet) - CaCO3
 6.Milk of Magnesia -Mg(OH)2
 7.Pepto-Bismol - HOC6H4COO
 8.Pepto-Bismol Childrens -CaCO3
 9.Rolaids -CaCO3 andMg(OH)2
 10.Tums -CaCO3
 11.Mylanta
USES OF ANTACID
 It bring down the percentage of acidity in our stomach
and prevent mucus lining in the stomach.
 It prevent from HEART BURN(acid form stomach
rising into esophagus )that can to our stomach lining .
 It also prevent from the ULCER(damageto lining of
stomach wall,resulting in loss of tissues and
inflammation).
Who cannot take antacid
 Patient with kidney failure or heart burn diseases
sodium Bicarbonate has high sodium content and is
not appropriate for peoplewhoare on salt restricted
diet or have congestive heart failure high blood
pressure or kidney problem .in pregnant if a lady is
pregnant antacid are safetous for heart burn symptoms
but do not use antacid .
CONCLUSION
 By reading gastric acidity (raising the intragastic pH)
antacids inactivate pepsin and relieve symptoms. Over
the counter preparations provide only temporary
symptom relief
REFERENCE
 Mohammed Ali,Pharmaceutical Chemistry-1
(Inorganic), antacid,1St edition(1955),lastedition 2021
THANK
YOU

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Arpaufxjfclhn Dutta.Inorganic chemistry.pdf

  • 1. SEACOM PHARMACY COLLEGE Presented by Arpan Dutta B.Pharm 1st Year;1st Semester Reg.No-233830210013 Roll No-38305923013 Antacid
  • 2. CONTENTS  Antacid .  Antacid Compounds.  Reaction of Antacid .  ACTION MECHANISM.  Requirement TO From the Antacid .  Antacid Are Available As Requirement .  SOME FAMOUS ANTACID BRANDS .  Uses of Antacid .  Who Cannot Take Antacid.  Conclusion.  Reference.
  • 3. ANTACID  An Antacid is any substance ,generallya base or basic salt, which neutralizes stomach acidity.theyare used to relieve acid indigestion ,upset stomach ,sour stomach ,and heartburn.
  • 4. Antacid Compounds  Antacids are weak base that are used to neutralize excess stomach acid.  Most antacids are weak inorganic bases  Common examples include CaCO3 NaHCO3 Al(OH)3 Mg(OH)3 MgO and Mg(OH)3 (Milk of Magnesia)
  • 5. Reaction of antacid  Antacids react with HCl in stomach  Some common antacid reactions include:  CaCO3+2HCl----CaCl2+H2O+CO2  NaHCO3+HCl----NaCl+H2O+CO2  Al(OH)3+3HCl----AlCl3+3H2O  Mg(OH)2+2 HCl----MgCl2+2H2O  MgO+2 HCl----MgCl2+H2O
  • 6. ACTION MECHANISM  Antacids perform a neutralization reaction ,i.e,they buffergastric acid ,rasing the pH to reduce acidity in the stomach, when gastric hydrochloric acid reaches the nerves in the gastrontestinal mucosa, they signal pain to the central nervous system .this happenswhen these nerves are exposed ,as in peptic ulcers. The gastric acid may also reach ulcers in the esophagusor the duodenum.
  • 7. Requirement TO Form Antacid  Burettes,pipettes,titration flasks,measuring flasks,beakers,weightbox,fractional weights,sodium hydroxide,sodiumcarbonate,hydrochloric acid,phenolphthalein.
  • 8. Antacid are Available As Requirement  Capsules.  Tablets.  Powder.  Chewabletablet.  Suspension.
  • 9. SOME FAMOUSN ANTACID BRANDS  1.Alka-Seltzer - NaHCO3 and/orKHCO3  2.Equate -Al(OH)3 andMg(oh)2  3.Gaviscon -Al(OH)3  4.Maalox(liquid) - Al(OH)3 and Mg(OH)2  5.Maalox(tablet) - CaCO3  6.Milk of Magnesia -Mg(OH)2  7.Pepto-Bismol - HOC6H4COO  8.Pepto-Bismol Childrens -CaCO3  9.Rolaids -CaCO3 andMg(OH)2  10.Tums -CaCO3  11.Mylanta
  • 10. USES OF ANTACID  It bring down the percentage of acidity in our stomach and prevent mucus lining in the stomach.  It prevent from HEART BURN(acid form stomach rising into esophagus )that can to our stomach lining .  It also prevent from the ULCER(damageto lining of stomach wall,resulting in loss of tissues and inflammation).
  • 11. Who cannot take antacid  Patient with kidney failure or heart burn diseases sodium Bicarbonate has high sodium content and is not appropriate for peoplewhoare on salt restricted diet or have congestive heart failure high blood pressure or kidney problem .in pregnant if a lady is pregnant antacid are safetous for heart burn symptoms but do not use antacid .
  • 12. CONCLUSION  By reading gastric acidity (raising the intragastic pH) antacids inactivate pepsin and relieve symptoms. Over the counter preparations provide only temporary symptom relief
  • 13. REFERENCE  Mohammed Ali,Pharmaceutical Chemistry-1 (Inorganic), antacid,1St edition(1955),lastedition 2021