The document discusses the applications and mechanisms of heat transfer in bioprocessing, highlighting its importance in biological processes and various industries such as food and beverage. It explains different types of heat exchangers, including double pipe, shell and tube, and plate-fin heat exchangers, focusing on their design, efficiency, and applications. Additionally, it covers the principles of heat transfer, laws governing thermal energy flow, and questions related to the topic.

1. APPLICATIONS OF HEAT TRANSFER
IN BIOPROCESSING
PRESENTED BY:-
AFROSE ASHIFA GULAM MOAHAMMED(121011101410)
AKR .SUSMIDHARANI(121011101433)
B.TECH BIOTECHNOLOGY(3rd Year)
SUBMITTED TO:-
Ms.P.MALA
(ASSISTANT PROFESSOR)
Department of biotechnology
PMIST
XBT602 PROCESS BIOTECHNOLOGY(UPSTREAM)

2. CONTENTS
• Heat transfer
• Types of heat transfer
• Heat exchanges
• Heat transfer in bioprocessing
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3. HEAT TRANSFER
• Heat transfer is the exchange of thermal energy between physical objects.
• Heat will naturally flow from a hotter to a colder object (2nd Law of Thermodynamics)
• Thermal equilibrium happens when all involved objects and their environment reach the same
temperature.
• There are essentially three ways that heat can be transferred: Conduction; Convection;
& Radiation
• CONDUCTION:-Happens when materials or in objects are in the direct contact with each other.
• CONVECTION:- Conduction is the process by which heat energy is transmitted through collisions
between neighboring atoms or molecules.
• RADIATION:-Radiation is energy that comes from a source and travels through space at the speed of
light.
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4. INTRODUCTION
APPLICATIONS OF HART TRANSFER IN BIOPROCESSING:-
1.To study a variety of biological phenomena, including cell signaling, gene expression, and
microbial ecology, mobile microorganisms can be utilized as model organisms.
2. Their mobility enables real-time monitoring and control of single cells or populations of cells.
3.By enhancing the passage of thermal energy between the particles and the surrounding fluid,
melting heat transport can further improve bio convection.
4. Heat exchangers find a variety of applications in various bioprocess industries in Food industry:
for production of juices, hazelnut pastes, yoghurts and other products, Ethanol production and
Beverage Industry for production of wines, beer, ethanol, vinegar etc., Cryogenic Processes and
Sterilization Techniques.
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5. FLUID FLOWS IN OPPOSITE
DIRECTION
FLUID FLOWS IN SAME
DIRECTION
FLOW ARRANGEMENTS
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https://images.app.goo.gl/FJ3DXLk72rtrEHPN8 https://images.app.goo.gl/jW4buybvyu5Ls4n6A

6. TYPES OF HEAT EXCHANGERS
DOUBLE PIPE HEAT EXCHANGER:-
• Double-pipe heat exchangers are devices that provide the transfer of thermal energy
between two fluids at different temperatures.
• The major use of these heat exchangers is the sensible heating or cooling process of
fluids where small heat transfer areas are required.
• The oil cooler is an example of these process used for efficient heat transfer between
two fluids.
• Double tube heat exchangers are designed whereby one tube is concentrically
positioned within a larger tube.
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7. DOUBLE PIPE EXCHANGER
• In a liquid-to-liquid heat interchanger, the fluid to be heated is passed only once through
the tubes before it gets discharged in single pass.
• The heat transfer in this case is not efficient.
• When few tubes per pass are desirable.
• double pipe heat exchanger is wo pipes are used: one is inserted in the other. The inside
pipe (or tube) is used for the pumping of cold liquid to be heated.
• The outer pipe acts as a jacket for the circulation of the hot liquid. All jacketed sections are
inter-connected and employed.
• The length of the pipe is also less.
• Glass tubes, standard iron pipes, and graphite constructions are available. Standard metal
pipes are assembled with standard return bends.
• A proper number of such pipes are connected in parallel and stacked vertically. The pipes
may have longitudinal fins on their outer surface.
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8. DOUBLE PIPE EXCAHNGER
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9. SHELL AND TUBE HEAT EXCAHNGER
SINGLE –PASS SHELL –AND HEAT TUBE EXCHANGER:-
• The shell-and-tube exchanger contains a large shell and many tubes. A
fluid stream passes through the tubes.
• Another stream passes through the shell to trade heat energy. The
improved heat transfer signifies a faster transfer rate and the higher heat
capacity of the system.
• These are used in the power industry such as feed water heaters and
power plant condensers.
• That are used in the petrochemical industry which tend to be covered by
standards from TEMA, Tubular Exchanger Manufacturers Association.
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10. SHELL AND TUBE HEAT EXCHANGER
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https://images.app.goo.gl/HBf93qfmQcBCnGZY9

11. DOUBLE PASS TUBE HEAT EXCHANGER
Double Pass Shell and Tube Heat Exchanger: -
• This heat exchanger includes many small thin tubes within a larger shell.
• Heat is transferred as fluid passes through the tubes and other fluid
travels across the shell side.
• The two fluids, one hot and the other cooler, flow through separate
chambers of the heat exchanger.
• The heat from the hot fluid dissipates through the wall separating the
two fluids into the cooler fluid.
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12. DOUBLE PASS TUBE HEAT EXCHANGER
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https://images.app.goo.gl/brJqduLVfjZFsK4q7

13. PLATE-FIN HEAT EXCHANGER
• The plate heat exchanger (PHE) is a specialized design well suited
to transferring heat between medium- and low-pressure fluids.
• Welded, semi-welded and brazed heat exchangers are used for heat
exchange between high-pressure fluids or where a more compact
product is required.
• Heat can thus be transferred from the hot fluid to the cold fluid if a hot
fluid and a cold fluid are separated by a heat-conducting surface.
• The operation of a heat exchanger is governed by thermodynamics.
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14. PLATE FIN HEAT EXCHANGER
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15. STEADY STATE HEAT EXCHANGER
• Steady state in any field means that the properties being measured do not change
with time. The system has finished evolving, and now the properties, when measured at a
point, do not change with time, whereas the they may or may not change with location
• So if we have any property ‘m’, then if the system is in steady state, we have -
• ∂∂m/∂∂t = 0 where ‘t’ is time
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16. STEADY STATE HEAT EXCHANGER
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17. QUESTIONS ?
1. Where does the heat flow from ? What is the law followed here.
2. What are three types of heat exchangers?
3. Name the two types of flow arrangements?
4. What are the applications of single pass shell and heat tube exchanger?
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18. ANSWER
• 1. the heat fliwflows to hot and cold surface.the law followed here is
fouriFourier law.
• 2.Double pipe heat exchange
• srteady state heat exchanger
• Single pass -shell heat exchange
• 3. FlluiFluid flows in opposite and same direction.
• 4. used in the chemical, food, oil and gas and other field.

19. REFERENCE
• https://www.zwirnerequipment.com/blog/what-is-a-double-tube-heat-
exchanger/
• https://compairindia.com/shell-and-tube-type-heat-
exchanger.html?gad_source=1&gclid=EAIaIQobChMIkIW8rO63hAMV_K
hmAh0KuAR3EAAYASAAEgIjovD_BwE
• https://nuclearpowertraining.tpub.com/h1018v1/css/Figure-3-Parallel-
Flow-Heat-Exchanger-73.htm
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