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Apoptosis

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Harshad Deshpande
Harshad Deshpande

general pathology , apoptosis...

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Apoptosis
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Cell Death NECROSIS APOPTOSIS
Apoptosis
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Features of Apoptosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],Simplyfy
Mechanism of Apoptosis ,[object Object],[object Object],[object Object]
Initiation Death Signals Death receptors : Type 1 TNF receptor EXTRINSIC (DEATH RECEPTOR) PATHWAY
Bcl 2 , Bcl x Anti-Apoptotic Proteins Bak, Bax, Bim Pro Apoptotic Proteins Cytochrome C Apaf-1 Caspase 9 INTRINSIC (M itochondrial) PATHWAY
Execution Phase ,[object Object],[object Object],[object Object],[object Object]
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Programmed Cell Death a step , towards “Life”
Cell Death : Necrosis / Apoptosis Features of Apoptosis Initiation (2 Pathways) & Execution p53 Anti Apoptotic genes Bcl 2 , Bcl x Pro Apoptotic genes Bak Bax Bim Thank You

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Apoptosis

  • 1.  
  • 3.
  • 4.  
  • 5. Cell Death NECROSIS APOPTOSIS
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13. Initiation Death Signals Death receptors : Type 1 TNF receptor EXTRINSIC (DEATH RECEPTOR) PATHWAY
  • 14. Bcl 2 , Bcl x Anti-Apoptotic Proteins Bak, Bax, Bim Pro Apoptotic Proteins Cytochrome C Apaf-1 Caspase 9 INTRINSIC (M itochondrial) PATHWAY
  • 15.
  • 16.
  • 17.  
  • 18.
  • 19. Programmed Cell Death a step , towards “Life”
  • 20. Cell Death : Necrosis / Apoptosis Features of Apoptosis Initiation (2 Pathways) & Execution p53 Anti Apoptotic genes Bcl 2 , Bcl x Pro Apoptotic genes Bak Bax Bim Thank You