In this month’s newsflash you can see the new range of veterinary antibodies available from BBI Solutions along with new analysis data for ST2 antibodies and CRP antibodies.

1. Newsflash
September 2014
New Products
Veterinary antibodies
New Antibody Data
ST2 recombinant Fabs
CRP recombinant Fabs
Capabilities
Monoclonal antibodies
Polyclonal antibodies
Recombinant Fab antibodies
Quality Partnership Results Innovation

2. Why choose BBI?
 Be confident in your results when you
choose BBI’s monoclonal antibodies for
your next assay:
 Tested in ELISA
 Tested in lateral flow
 Recommended pairings provided
 Strong customer feedback
 We have now introduced highly sensitive
recombinant Fab antibodies to improve
your next generation assays.
 New this month – new veterinary
antibodies for companion and livestock
animals.
Quick Links
NEW
Veterinary Antibodies >
ST2 ELISA Data >
CRP Affinity Data >
Monoclonal Antibodies >
Polyclonal Antibodies >
Recombinant Fab
Antibodies >
How to Order >

3. NEW Veterinary Antibodies
 New range of veterinary antibodies targeted to a variety of companion and
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livestock animals.
 Tested in lateral flow with recommended matched pairings.
Marker Capture Antibody Detection Antibody
CDV (Canine Distemper Virus) BM417-D1A6 BM417-D1A6
Avian Influenza Virus H5 BM422-Z3D1 BM422-P6H1
FeLV BM419-E7A5 BM419-O6H1
Brucella LPS BM420-G9E1 BM420-M9D1
Giardia BM423-V5C5 BM423-V5C5
Enrofloxacin BM427-Z6C6 BM427-Z6C6
Goat IgG BM418-G7B1 or BM418-K5D1 BM418-G7B1 or BM418-K5D1
Canine IgM BM424-S6B1
BM424-T7H1
BM424-T7H1
BM424-S6B1
Swine IgG BM425-S6H4
Chicken IgY BM421-P5G5 or BM421-M6B6 BM421-M6B6 or BM421-P5G5
GST (Glutathione S-transferase) BM426-H9E9

4. NEW Veterinary Antibodies
Avian Influenza Virus H5 Strain Antibody
Marker Capture
Antibody
Detection
Antibody
Avian Influenza
Virus H5
BM422-Z3D1 BM422-P6H1
Proven performance in lateral flow
 The image shows BM422-Z3D1 as capture antibody
and BM422-P6H1 as detection antibody in a
sandwich assay format.
 This antibody pair is able to detect all H5 subtypes
of Avian Influenza Virus.
 Lane 1 – Cultured Avian Influenza Virus
 Lane 2 – Buffer only
1 2
The H5 strain of Avian Influenza is
currently prevalent in Europe and
Asia, where there are 9 known
subtypes.
Images have not been altered for brightness or contrast. The antibody is not self-pairing.
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5. NEW Veterinary Antibodies
Giardia Antibody
Marker Capture
Antibody
Detection
Antibody
Giardia BM423-V5C5 BM423-V5C5
Proven performance in Lateral Flow
 The image shows BM423-V5C5 used as both a
capture and detection antibody to detect Giardia in a
sample from an infected dog.
 The antibody is self-pairing.
 Lane 1 – Giardia-infected dog stool sample
 Lane 2 – Buffer only
1 2
Giardia is a parasite of the intestine
affecting both domestic and wild
animals along with humans.
Images have not been altered for brightness or contrast. The antibody is not self-pairing.
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6. Antibody Spotlight
New Data – ST2 recombinant Fab
 Recommended for use within ELISA.
 Provided with recommended pairings and range of detection.
Capture Antibody Detection Antibody Range of Detection
BR139-S7B7 BR139-V8D4 1.39 – 97 ng / ml
BR139-T3G5 BR139-V8D4 0.08 – 31 ng / ml
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7. Antibody Spotlight
New Data – CRP recombinant Fab affinity data
 Biotinylated antigen was immobilised onto a streptavidin sensor. Ka, Kd and KD
measured on the Octet system.
 Our CRP recombinant Fab antibody has a picomolar affinity of 139pm.
70.5 nM
35.2 nM
17.6
nM
8.81
nM
KD (nM)
0.138
Kon (1/Ms)
233400 ± 275
Kdis (1/s)
3.23 x 10-5 ±
1.78 x 10-7
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8. Our Capabilities | Monoclonal Antibodies
Cardiac Infectious Disease Norovirus Pregnancy
CK-MB C. difficile Toxin A PBP2a AFP
D-Dimer C. difficile Toxin B TB
Myoglobin Chikungunya Veterinary
Troponin I Dengue NS1 Tumour Canine Distemper
H. pylori CA125 Virus
Diabetes HAV CA15-3 Avian Influenza H5
Hb HBV CA19-9 FeLV
HbA1c Hepatitis B Calcitonin Brucella LPS
HIV p24 Enrofloxacin
Drugs of abuse HIV gp35 Immunoglobulins Goat IgG
THCΔ9 HIV gp41 IgA Canine IgM
Influenza A IgE Chicken IgY
Hormones Influenza B IgG GST
Progesterone Leptospira IgM
PTH Listeria
Malaria HRP2
Malaria LHD (pan)
Malaria LHD (Pf)
Malaria LDH (Pf & Pv) Return home >

9. Our Capabilities | Polyclonal Antibodies
Inflammation Pregnancy Renal
CRP AFP A2M
B2M
Hormones Inflammatory Cystatin C
HCG A1AT
αHCG
Haematology Metabolism
Immunoglobulins Haptoglobin Ceruloplasmin
IgA Ferritin
IgM Haemoglobin
IgG
Albumin
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10. Our Capabilities | Recombinant Fab Antibodies
Biomarker Detection Range* Capture Antibody Detection Antibody
HSP60 0.1 - 1200 ng/mL BR100-G2A7 BR100-H4C2
Adiponectin 0.1 - 525 ng/mL BR101-P7E2 BR101-M3H8
Adiponectin 230 - 59118 ng/mL BR101-H2B4 (Competitive ELISA)
Angiopoietin 2 0.001 - 97 ng/mL BR103-P4E8 BR103-V5F2
Big Endothelin 1 0.001 - 1.8 ng/mL BR104-D6A4 BR104-H1A4
Calcitonin 0.006 - 2 ng/mL BR388-G6B1 BR388-D5C4
Cathepsin D 0.03 - 150 ng/mL BR107-F5G2 BR107-K6D3
Eotaxin 0.007 - 2 ng/mL BR108-M7H3 BR108-K2D9
Chondrolectin 0.9 - 21 ng/mL BR111-P8G3 BR111-T6B1
CKBB 0.15 - 33 ng/mL BR112-V6F6 BR112-Z1C4
Proinsulin C-Peptide 0.09 - 38 ng/mL BR143-G5D3 BR143-K7C9
CRP 151 - 231000 ng/mL BR228-D4A3 (Competitive ELISA)
Cystatin C 165 - 9073 ng/mL BR175-G8D9 (Competitive ELISA)
Cystatin C 165 - 9073 ng/mL BR175-H4C8 (Competitive ELISA)
E. histolytica not tested BR116-K9F7 BR116-G3A1
E-selectin 0.05 - 235 ng/mL BR117-K2E7 BR117-H5B6
FABP Intestine 0.65 - 100 ng/mL BR115-F7G7 BR115-G6B9
FABP Liver 0.03 - 90 ng/mL BR106-G5A2 BR106-P9F5
* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation
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11. Our Capabilities | Recombinant Fab Antibodies
Biomarker Detection Range* Capture Antibody Detection Antibody
G. lamblia not tested BR120-P3F2 & BR120-T1G8
Human Fetal Hemoglobin 1.9 - 305 ng/mL BR121-T5H9 BR121-V5A7
Leptin 3.9 - 691 ng/mL BR123-M4D6 BR123-P4G2
MMP7 0.1 - 293 ng/mL BR124-S4E3 BR124-T6G8
MMP9 Active 11 - 183 ng/mL BR125-N5F7 BR125-M6D6
MPO 2 - 1200 ng/mL BR240-N5G6 BR240-D8B4
Neutrophil Elastase 0.008 - 33 ng/mL BR127-H2A4 BR127-G7C2
Free PAPP A 0.3 - 299 ng/mL BR129-M5E3 BR129-F2H4
Pentraxin 3 4.6 - 876 ng/mL BR130-H2C3 BR130-K6D6
PGDS 0.2 - 85 ng/mL BR131-M6H7 BR131-P7F7
PSAP A 0.013 - 123 ng/mL BR132-T5G4 BR132-S6E4
PSAP B 0.3 - 1500 ng/mL BR133-V6B5 BR133-V4D1
RBP 4 350 - 500000 ng/mL BR134-Z7D3 (Competitive ELISA)
S100 Beta 0.04 - 5.6 ng/mL BR332-G4B9 BR332-F5H7
ST2 1.39 - 97 ng/mL BR139-S7B7 BR139-V8D4
ST2 0.08 - 31 ng/mL BR139-T3G5 BR139-V8D4
Tie2 0.8 - 600 ng/mL BR140-Z7A5 BR140-D9D7
* Detection Ranges are assay dependent and optimised for specific
clinical conditions, therefore may be improved with optimisation
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12. How to Order
Please get in touch to arrange a quote for
any of our products.
You can also order directly via our website
www.bbisolutions.com
info@bbisolutions.com
USA: 1-800-423-8199
Intl: +44 (0) 2920 747 232
Quote on ordering – NF SEP
BBI Solutions
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