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TOPIC : TRANSPLANTATION AND DONOR TyPeS
PRESENTED TO :
DR.NAGESH.N,
ASSISTENT PROFESER,
DEPT.OF BIOTECHNOLOGY,
AGRICULTURAL COLLEGE HASSAN .
PRESENTED BY :
MANOJ.B.S,
BLH1027.

TRANSPLANTATION
AND DONOR TyPeS
 DEFINATION-
It can be defined as moving of an
organ from one body to another that is
from donor site to patient body for the
purpose of replacing recipient’s
damaged , absent or missed organ.

INTRODUCTION
 Transplantation medicine is one of the most
challenging and complex area as it has the major
problem of rejection of transplanted organ by
recipient body…
 During transplantation a recipient’s body has an
immune response to transplanted organ and that may
lead to transplant failure.
 The acceptable organ donor can range from new
borne infant to 80 years age.

 This transplantation rejection problem
can be reduced by-
-serotyping to determine the most
appropriate donor-recipient match.
-by using the immune suppressant
drug.

1st
heart transplantation was done in 1967
by- Christian barnard in S. Africa..
1st
kidney transplantation was done in 1954
by- Joseph massay in USA.
1st
steps in transplantation

1. Auto graft.
2. Allografting.
3. Iso graft.
4. Xeno grafting.
5. Split graft .
6. Domino transplants.
TYPES OF
TRANSPLANTATION

It refers that transplantation of tissue
within the organism’s body that is to
the same body from one region to
another.
Eg: skin grafting
AUTO GRAFT

It refers that transplanting an organ or
tissue between 2 genetically non identical
members of same species.
Eg: most of the human tissue and organ
transplants are known as allo grafts
ALLO GRAFTING

It refers to transplantation of an organ
or tissue between 2 genetically
identical organisms or identical
persons.
Eg: between the twins.
ISO GRAFT

It refers to the transplantation of an organ
or tissue between 2 species that is from one
species to another.
Eg: Porcine heart valve transplantation
(It is quite common and successful but
they are often dangerous)
XENO GRAFTING

Here as the name indicates donated organ is
divided and used for 2 recipients.
Eg: Liver transplantation
(It is usually not preferred as we know that
transplantation of whole organ is only
successful)
SPLIT GRAFT

It is usually performed in the cystic fibrosis
patients since here both lungs and heart
needs to be replaced and it is easier
method of replacing both at same time
Eg: heart and lungs replacement in cystic
fibrosis patients
DOMINO TRANSPLANTS

 There are 2 types mainly…..
1.Living donor.
2.Diseased donor.
TYPES OF DONOR

In this case donor remains alive and
donates renewable tissue, cell, fluid or even
may be organ or part of an organ which can
be regenerated or the work load can be
taken off by rest of the organ
Eg: blood, skin, kidney donation
LIVING DONOR

 In this case the donor is declared as
patients and their organs are kept
alive or viable using ventilators and
other mechanical methods until they
are excised for transplantation
DISEASED DONOR

 If any organ is absent or missed it can be regained
through this techniques.
 Damaged organs can be replaced.
 Many diseases related to blood, failure in organ
working etc.. can be treated by this transplantation
techniques.
APLLICATIONS:

REFERECES:
“ Animal biotechnology
Recent Concepts and Development”
-P. RAMADASS
THANK
Q……

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TRANSPLANTATION AND DONOR TYPES

  • 1. TOPIC : TRANSPLANTATION AND DONOR TyPeS PRESENTED TO : DR.NAGESH.N, ASSISTENT PROFESER, DEPT.OF BIOTECHNOLOGY, AGRICULTURAL COLLEGE HASSAN . PRESENTED BY : MANOJ.B.S, BLH1027.
  • 3.  DEFINATION- It can be defined as moving of an organ from one body to another that is from donor site to patient body for the purpose of replacing recipient’s damaged , absent or missed organ.
  • 4.  INTRODUCTION  Transplantation medicine is one of the most challenging and complex area as it has the major problem of rejection of transplanted organ by recipient body…  During transplantation a recipient’s body has an immune response to transplanted organ and that may lead to transplant failure.  The acceptable organ donor can range from new borne infant to 80 years age.
  • 5.   This transplantation rejection problem can be reduced by- -serotyping to determine the most appropriate donor-recipient match. -by using the immune suppressant drug.
  • 6.  1st heart transplantation was done in 1967 by- Christian barnard in S. Africa.. 1st kidney transplantation was done in 1954 by- Joseph massay in USA. 1st steps in transplantation
  • 7.  1. Auto graft. 2. Allografting. 3. Iso graft. 4. Xeno grafting. 5. Split graft . 6. Domino transplants. TYPES OF TRANSPLANTATION
  • 8.  It refers that transplantation of tissue within the organism’s body that is to the same body from one region to another. Eg: skin grafting AUTO GRAFT
  • 9.  It refers that transplanting an organ or tissue between 2 genetically non identical members of same species. Eg: most of the human tissue and organ transplants are known as allo grafts ALLO GRAFTING
  • 10.  It refers to transplantation of an organ or tissue between 2 genetically identical organisms or identical persons. Eg: between the twins. ISO GRAFT
  • 11.  It refers to the transplantation of an organ or tissue between 2 species that is from one species to another. Eg: Porcine heart valve transplantation (It is quite common and successful but they are often dangerous) XENO GRAFTING
  • 12.
  • 13.  Here as the name indicates donated organ is divided and used for 2 recipients. Eg: Liver transplantation (It is usually not preferred as we know that transplantation of whole organ is only successful) SPLIT GRAFT
  • 14.  It is usually performed in the cystic fibrosis patients since here both lungs and heart needs to be replaced and it is easier method of replacing both at same time Eg: heart and lungs replacement in cystic fibrosis patients DOMINO TRANSPLANTS
  • 15.   There are 2 types mainly….. 1.Living donor. 2.Diseased donor. TYPES OF DONOR
  • 16.  In this case donor remains alive and donates renewable tissue, cell, fluid or even may be organ or part of an organ which can be regenerated or the work load can be taken off by rest of the organ Eg: blood, skin, kidney donation LIVING DONOR
  • 17.   In this case the donor is declared as patients and their organs are kept alive or viable using ventilators and other mechanical methods until they are excised for transplantation DISEASED DONOR
  • 18.   If any organ is absent or missed it can be regained through this techniques.  Damaged organs can be replaced.  Many diseases related to blood, failure in organ working etc.. can be treated by this transplantation techniques. APLLICATIONS:
  • 19.  REFERECES: “ Animal biotechnology Recent Concepts and Development” -P. RAMADASS