The document provides an overview of the major human body systems, their main organs and functions, and how they typically change with aging. It discusses the integumentary, circulatory, respiratory, musculoskeletal, gastrointestinal, renal, endocrine, nervous, immune, and reproductive systems. For each system it lists the main organs, their functions in the body, and common changes that occur with aging such as dryer skin, stiffer muscles, slower reflexes, and increased disease risk.