Daily chlorhexidine baths were introduced on a 50-bed medical surgical unit to reduce central line-associated bloodstream infections (CLABSIs). CLABSIs contribute to increased mortality, length of stay, and costs. Literature shows that chlorhexidine baths as part of a CLABSI bundle can significantly reduce infection rates when used in preoperative and critical care areas. After implementing daily chlorhexidine baths for all patients with central lines, inconsistencies were found in bathing technique and documentation. Some patients refused baths due to feeling cold or itchy. While the program has been in place for four months, the unit's CLABSI rates have not decreased and remain above benchmark rates.