In the current study, we have experimentally and comparatively
investigated and compared malignant human cancer cells and
tissues before and aft er irradiating of synchrotron radiation using Small-Angle X-Ray Scattering (SAXS), Ultra-Small Angle X-Ray Scattering (USAXS), Fluctuation X-Ray Scattering (FXS)
Cancer gwas and genetic risk predictionDavid Enoma
Genome wide association studes and its application in cancer as well as genetic risk prediction scoring for cancers. Especially in populations of African ancestry.
This document summarizes three papers on population genetics and genomics research in African populations. The first paper discusses the African Genome Variation Project, which characterized genetic diversity in Africa and improved genomic studies on the continent. The second paper reviews pharmacogenetics studies in African populations, finding relatively few but highlighting their importance. The third paper summarizes prostate cancer genome-wide association studies, including initial studies identifying risk loci and more recent work identifying additional variants in African populations.
Lopez-Bigas talk at the EBI/EMBL Cancer Genomics WorkshopNuria Lopez-Bigas
The document describes an oncogenomics workshop discussing methods for identifying cancer driver genes from tumor sequencing data. It introduces two computational methods developed by the speaker's group called OncodriveFM and OncodriveCLUST that identify drivers by looking at the functional impact of mutations and regional mutation clustering, respectively. These methods can be applied across multiple cancer sequencing projects in a scalable way without needing raw sequencing data. The International Cancer Genome Consortium's IntOGen database currently analyzes over 3,000 tumor samples across 27 cancer projects using these and other methods.
This document describes a new blood test using gold nanoparticles and dynamic light scattering to detect early stage cancers. The test analyzes the protein corona that forms on the nanoparticles when mixed with blood serum. It was discovered that serum from prostate cancer patients forms a corona with higher levels of immunoglobulin G (IgG) compared to non-cancer controls. Two studies showed the test has 90-95% specificity and 50% sensitivity for early prostate cancer, improving on PSA testing. The increased IgG is believed to be from autoantibodies produced against tumors. The simple test requires only a few drops of blood and provides rapid results, making it suitable for cancer screening.
EIS Technology: bioimpedance chronoamperometry in adjunct to screen the prost...ES-Teck India
Through the 6 tactile electrodes, a weak DC current is sending alternatively between 2 electrodes with a sequence and the EIS system is recording the electrical conductance of 11 pathways of the human body.
This document describes a study that used a portable multiphoton gradient index (GRIN) endoscope to image unprocessed ex vivo human prostate tissue samples obtained from radical prostatectomy patients. The endoscope produced images at subcellular resolution and was able to identify differences between benign and malignant prostate tissue as well as other prostatic and periprostatic tissues. The study aims to evaluate the potential for multiphoton GRIN endoscopy to serve as a diagnostic tool for prostate cancer.
This study compared genomic data from 39 HNSCC cell lines to genomic findings from 106 HNSCC tumors. Amplification of eight genes and deletion of five genes were found in both cell lines and tumors. Seventeen genes were only mutated in cell lines, suggesting these mutations arose in tissue culture. Conversely, 11 genes were only mutated in over 10% of tumors. Several mutant genes in the EGFR pathway were shared between cell lines and tumors. Pharmacologic profiling of six cell lines suggested PIK3CA mutation may predict sensitivity to EGFR/PI3K pathway drugs. These findings suggest correlating gene mutations between cell lines and tumors can guide selection of preclinical models.
Genomics 2015 Keynote - Utilizing cancer sequencing in the clinicAndreas Scherer
Dr. Andreas Scherer discussed Golden Helix's bioinformatics tools and pipelines for analyzing cancer sequencing data. Golden Helix has over 20 years of experience in developing software for variant analysis, annotation, and reporting. Their tools can align sequencing reads, call variants, annotate variants with public databases, perform tumor-normal comparisons to identify somatic mutations, and generate clinical reports on pathogenic variants relevant for cancer treatment. Dr. Scherer emphasized the challenges of variant annotation and described Golden Helix's extensive variant databases and customization options to support clinical cancer sequencing workflows.
Cancer gwas and genetic risk predictionDavid Enoma
Genome wide association studes and its application in cancer as well as genetic risk prediction scoring for cancers. Especially in populations of African ancestry.
This document summarizes three papers on population genetics and genomics research in African populations. The first paper discusses the African Genome Variation Project, which characterized genetic diversity in Africa and improved genomic studies on the continent. The second paper reviews pharmacogenetics studies in African populations, finding relatively few but highlighting their importance. The third paper summarizes prostate cancer genome-wide association studies, including initial studies identifying risk loci and more recent work identifying additional variants in African populations.
Lopez-Bigas talk at the EBI/EMBL Cancer Genomics WorkshopNuria Lopez-Bigas
The document describes an oncogenomics workshop discussing methods for identifying cancer driver genes from tumor sequencing data. It introduces two computational methods developed by the speaker's group called OncodriveFM and OncodriveCLUST that identify drivers by looking at the functional impact of mutations and regional mutation clustering, respectively. These methods can be applied across multiple cancer sequencing projects in a scalable way without needing raw sequencing data. The International Cancer Genome Consortium's IntOGen database currently analyzes over 3,000 tumor samples across 27 cancer projects using these and other methods.
This document describes a new blood test using gold nanoparticles and dynamic light scattering to detect early stage cancers. The test analyzes the protein corona that forms on the nanoparticles when mixed with blood serum. It was discovered that serum from prostate cancer patients forms a corona with higher levels of immunoglobulin G (IgG) compared to non-cancer controls. Two studies showed the test has 90-95% specificity and 50% sensitivity for early prostate cancer, improving on PSA testing. The increased IgG is believed to be from autoantibodies produced against tumors. The simple test requires only a few drops of blood and provides rapid results, making it suitable for cancer screening.
EIS Technology: bioimpedance chronoamperometry in adjunct to screen the prost...ES-Teck India
Through the 6 tactile electrodes, a weak DC current is sending alternatively between 2 electrodes with a sequence and the EIS system is recording the electrical conductance of 11 pathways of the human body.
This document describes a study that used a portable multiphoton gradient index (GRIN) endoscope to image unprocessed ex vivo human prostate tissue samples obtained from radical prostatectomy patients. The endoscope produced images at subcellular resolution and was able to identify differences between benign and malignant prostate tissue as well as other prostatic and periprostatic tissues. The study aims to evaluate the potential for multiphoton GRIN endoscopy to serve as a diagnostic tool for prostate cancer.
This study compared genomic data from 39 HNSCC cell lines to genomic findings from 106 HNSCC tumors. Amplification of eight genes and deletion of five genes were found in both cell lines and tumors. Seventeen genes were only mutated in cell lines, suggesting these mutations arose in tissue culture. Conversely, 11 genes were only mutated in over 10% of tumors. Several mutant genes in the EGFR pathway were shared between cell lines and tumors. Pharmacologic profiling of six cell lines suggested PIK3CA mutation may predict sensitivity to EGFR/PI3K pathway drugs. These findings suggest correlating gene mutations between cell lines and tumors can guide selection of preclinical models.
Genomics 2015 Keynote - Utilizing cancer sequencing in the clinicAndreas Scherer
Dr. Andreas Scherer discussed Golden Helix's bioinformatics tools and pipelines for analyzing cancer sequencing data. Golden Helix has over 20 years of experience in developing software for variant analysis, annotation, and reporting. Their tools can align sequencing reads, call variants, annotate variants with public databases, perform tumor-normal comparisons to identify somatic mutations, and generate clinical reports on pathogenic variants relevant for cancer treatment. Dr. Scherer emphasized the challenges of variant annotation and described Golden Helix's extensive variant databases and customization options to support clinical cancer sequencing workflows.
Development and Validation of a Two-Site Immunoradiometric assay for Glypican...Premier Publishers
This study aimed to develop and validate an immunoradiometric assay (IRMA) to measure glypican-3 (GPC3) levels in plasma samples and evaluate its diagnostic potential for hepatocellular carcinoma (HCC). The researchers established an IRMA to measure GPC3 and compared its performance to a commercial ELISA kit using plasma samples from 150 HCC patients, 150 hepatitis C patients, and 150 healthy controls. The IRMA showed better diagnostic accuracy than the ELISA kit for distinguishing HCC patients from controls and hepatitis C patients based on receiver operating characteristic analysis. Using the optimized IRMA, the study found that GPC3 levels could help discriminate HCC from hepatitis C with high sensitivity and specificity and was a
Analytical performance of a novel next generation sequencing assay for Myeloi...Thermo Fisher Scientific
To support clinical and translational research into precision oncology strategies for myeloid cancers, a next-generation sequencing (NGS) assay was developed to detect common and relevant somatic alterations. To define gene targets that were recurrently altered in myeloid cancers and relevant for clinical and translational research, an extensive survey of investigators at hematology oncology research labs was performed.
1) The document discusses the Halsted and Fisher hypotheses regarding breast cancer treatment. The Halsted hypothesis viewed breast cancer as spreading in an orderly manner from the breast to lymph nodes to distant sites, supporting radical mastectomy. The Fisher hypothesis viewed breast cancer as a systemic disease at diagnosis.
2) Recent evidence from NSABP trials suggests local therapy and local recurrence may affect survival outcomes, challenging the Fisher hypothesis. Patients who experienced local recurrence had higher risks of distant disease and mortality. Improved local control with radiotherapy was associated with decreased breast cancer deaths.
3) The evidence indicates that both local and systemic factors play a role in breast cancer, supporting an approach that considers both.
This document describes the characterization of a new head and neck squamous cell carcinoma (HNSCC) cell line called USC-HN2. USC-HN2 was established from a patient with recurrent oral cavity cancer. Characterization showed USC-HN2 has properties typical of aggressive oral HNSCC, including expression of markers like EGFR, CD44v6, and FABP5. Testing revealed USC-HN2 strongly induces regulatory T cells and myeloid-derived suppressor cells in vitro, suggesting an immunosuppressive phenotype. Comparison to another HNSCC cell line, SCCL-MT1, showed both lines have robust cytokine production and immune cell induction, making them useful models for
In Silico Prescription of Anticancer Drugs Reveals Targeting OpportunitiesNuria Lopez-Bigas
Large efforts dedicated to sequence thousands of tumor genome/exomes are expected to lead to significant improvements of precision cancer medicine. However, high inter-tumor heterogeneity is a major obstacle in the road to develop an arsenal of targeted cancer drugs to treat most cancer patients. Therefore, it is critical to understand the current scope of anti-cancer targeted drugs for different tumor types in order to use them with the highest efficacy, and to define priorities for the development of new ones. We have developed a novel methodology to interpret the genomes of a cohort of tumor samples and to assess their therapeutic opportunities. Starting with somatic mutations detected across the cohort, the methodology identifies the driver genes, highlights those that dominate the clonal landscape of the tumors and determines their mode of action. It then does an in-silico prescription of approved and candidate targeted drugs to each patient in the cohort. The application of this approach to a cohort of 6795 cancer samples of 28 different tumor types showed that the fraction of patients that could benefit from prescribed FDA-approved drugs is strikingly small. Nevertheless, it improves significantly if repurposing opportunities are taken into consideration, with large differences between tumor types. In addition, we identify 80 therapeutically unexploited cancer genes, tightly bound by pre-clinical small molecules or potentially suitable for molecule binding. The resource created with this analysis is also intended to provide interpretation of newly sequenced cancer genomes and to design pan-cancer and tumor type specific sequencing panels for efficient early cancer detection and clinical insight.
More details at http://www.intogen.org
kSORTTM is a non-invasive blood test that analyzes gene expression to assess immune risk in kidney transplant patients. The analytical performance of kSORTTM was validated in an independent clinical laboratory. Accuracy was high, with 87% agreement between kSORTTM results and biopsy results. Precision studies showed 15% variability in quantitative scores and 94% consistency in qualitative results over multiple runs. Sensitivity was 100% and specificity was 96% when excluding indeterminate results. Validation demonstrates that kSORTTM is analytically sound for clinical use in monitoring transplant patients.
This document discusses genomic oncology and personalized medicine, using lung cancers as a model. It summarizes several key technologies that enable genomic oncology like cDNA microarrays, array CGH, and next generation sequencing. It provides examples of how these technologies have been used to classify cancers like diffuse large B-cell lymphoma and myelodysplastic syndrome, and identify genetic mutations that can guide targeted therapies for cancers like EGFR-mutated lung cancer.
NSA Diagnostic Laboratory has been operating since 1958, founded by Prof. Nasseh Amin. NSA is considered as one of the most advanced labs in Egypt. Maintaining personalized services for its stakeholders, as well as the main role of the lab "Diagnosis"
NSA Diagnostic Laboratory operates through two different segments.
Firstly, a group of stand-alone labs located at prime locations all over Egypt, with the latest and up to date equipments.
Secondly, being the backbone of well reputed hospitals and some polyclinics where NSA is the lab that is responsible for all medical testing there, serving all our patients with class A quality.
Our main focus is delivering quality care and with Cost-value return. NSA plays a key role in improving the health of many Egyptians, by providing access to quality service for more than 200,000 patients annually.
This curriculum vitae outlines the educational background and professional experience of Dr. Waleed O. Arafat. He received his M.B.B.Ch. in 1989 from the University of Alexandria Faculty of Medicine in Egypt and his PHD in clinical oncology in 2002. He has held positions at several institutions and currently serves as an assistant professor in clinical oncology at the University of Alexandria. His areas of research interest include translational cancer research, gene therapy, and radiotherapy. He has over 30 publications in peer-reviewed journals and has presented his research findings at numerous conferences.
Identification of cancer drivers across tumor typesNuria Lopez-Bigas
Thousands of tumor genomes/exomes are being sequenced as part of the International Cancer Genome Consortium (ICGC), The Cancer Genome Atlas (TCGA) and other initiatives. This opens the possibility to have, for the first time, a comprehensive picture of mutations, genes and pathways involved in the cancer phenotype across tumor types. We have developed computational methods able to identify signals of positive selection in the pattern of tumor somatic mutations, which point to genes and pathways directly involved in the development of the tumors. We have applied these approaches to 3025 tumors from 12 different cancer types of the TCGA Pan-Cancer project, identifying 291 high-confidence cancer driver genes acting on those tumors (Tamborero et al 2013). We have also developed IntOGen-mutations (http://www.intogen.org/mutations), a novel web platform for cancer genomes interpretations, which analyses not only TCGA pan-cancer data but all mutation data from ICGC and other initiatives. The resource allows users to identify driver mutations, genes and pathways acting on more than 6000 tumors originated in 17 different cancer sites and to analyze newly sequence tumor genomes. Among the novel cancer drivers identified there are chromatin regulatory factors and splicing factors, which are emerging as important genes in cancer development and are regarded as interesting candidates for novel targets for cancer treatment. In my talk I will summarize all these recent findings.
More info: http://bg.upf.edu/blog/2013/10/my-slides-on-identification-of-cancer-drivers-across-tumor-types/
This document discusses the use of radioisotopes, particularly iodine isotopes, in medical applications like diagnosis and treatment of thyroid disorders and cancers. It describes techniques like radioimmunoassay (RIA), radioimmunolocalization (RIL), radioimmunotherapy, and thyroid scanning that use radioisotopes. RIA uses radioisotope-labeled antigens or antibodies to detect substances in the body, while RIL and radioimmunotherapy use labeled antibodies to detect and treat tumors. Thyroid scanning uses various iodine isotopes to evaluate thyroid function and detect abnormalities.
This is a history of that my www.alphataumedical.com platform technology that is the most effective therapy for all solid tumor with the bonuses of no, there cannot be, side effects, dissolving tumors in days and its alpha particles uniquely are the only type of radiation that cuts both helices of the tumor’s DNA.
The Presence and Persistence of Resistant and Stem Cell-Like Tumor Cells as a...QIAGEN
Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths of women in the United States and Europe and ranks as the second most common type of gynecological malignancy. Most cases are diagnosed in advanced stages and although the response rates to platinum-based chemotherapy are high, the majority of patients nevertheless have poor survival rates. Although the reasons for these poor outcomes are likely to be multifactorial, one particular area of interest has recently focused on hematogenous tumor cell dissemination that has been shown to originate from disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in the blood. Here, we demonstrate that the negative prognostic impact of CTCs and DTCs arise from specific cellular phenotypes and are associated with platinum-resistance and stem cell-associated proteins.
The document discusses next generation sequencing and its applications in cancer research. It notes that NGS allows studying genetic variations at the individual base level in a fast and affordable manner. The document also distinguishes between driver mutations, which confer a growth advantage to cancer cells, and passenger mutations, which do not directly contribute to cancer. Driver mutations can inactivate tumor suppressor genes or activate oncogenes.
A new assay for measuring chromosome instability (CIN) and identification of...Enrique Moreno Gonzalez
This document describes a new assay for measuring chromosome instability (CIN) using a human artificial chromosome (HAC) carrying a fluorescent marker. The assay allows quantification of HAC loss after drug treatment via flow cytometry. Several known anti-mitotic drugs were tested and found to increase HAC loss rates to varying degrees, with microtubule-stabilizing drugs taxol and peloruside A showing the highest increases in CIN. This new assay provides a simple and efficient way to screen drugs and identify those that elevate CIN, with the goal of developing new cancer therapies targeting chromosomally unstable tumors.
1. The document discusses studies comparing adjuvant radiation therapy to salvage radiation therapy for prostate cancer patients with adverse pathological features after radical prostatectomy.
2. The EORTC 22911 trial randomized over 1000 patients to either observation or adjuvant radiation and found significantly improved biochemical progression-free survival with adjuvant radiation.
3. Other large trials including SWOG and ARO 96-02 also found benefits to adjuvant radiation in reducing risks of biochemical recurrence, distant metastases and death from prostate cancer.
Cancer Care Delivery Gaps in India based on EY ReportsPuneet Seth
This document discusses gaps in cancer care delivery in central India and proposes establishing a comprehensive cancer care center. It notes that cancer cells can reproduce rapidly, growing from one million to one billion cells in as little as 6 weeks. There are key barriers to timely diagnosis and treatment of cancer as well as a lack of adequate radiation therapy infrastructure and oncologists, especially outside of major metro areas. A comprehensive cancer care center could help address these issues and improve access to high quality cancer treatment.
The document summarizes research using chick embryo models to study cancer metastasis. It describes several advantages of the chick embryo model, including its ability to support rapid growth of xenografted human tumor cells. Several chick embryo cancer models are outlined, including models for spontaneous metastasis, analyzing tumor cell interactions with vasculature, and studying invasion and extravasation. Examples are given of studies using these models to analyze tumor growth and metastasis of various cancer cell lines and effects of potential therapeutics.
Knocking on the clinic door of precision medicine Yoon Sup Choi
1. Recent advances in precision oncology are based on next-generation sequencing (NGS) which has improved precision medicine for cancer patients.
2. Technologies like NGS have enabled more precise cancer diagnosis and treatment by identifying genetic mutations in tumors that can be targeted by specific therapies.
3. However, tumor heterogeneity, where different mutations exist between and within tumors, remains a challenge as it can cause resistance to targeted therapies.
In the current study, we have experimentally and comparatively
investigated and compared malignant human cancer cells and tissues before and aft er irradiating of synchrotron radiation using Lase Spectroscopy, Laser–Induced Breakdown Spectroscopy (LIBS) and Laser-Induced Plasma Spectroscopy (LIPS). It is clear that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passage of time
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Development and Validation of a Two-Site Immunoradiometric assay for Glypican...Premier Publishers
This study aimed to develop and validate an immunoradiometric assay (IRMA) to measure glypican-3 (GPC3) levels in plasma samples and evaluate its diagnostic potential for hepatocellular carcinoma (HCC). The researchers established an IRMA to measure GPC3 and compared its performance to a commercial ELISA kit using plasma samples from 150 HCC patients, 150 hepatitis C patients, and 150 healthy controls. The IRMA showed better diagnostic accuracy than the ELISA kit for distinguishing HCC patients from controls and hepatitis C patients based on receiver operating characteristic analysis. Using the optimized IRMA, the study found that GPC3 levels could help discriminate HCC from hepatitis C with high sensitivity and specificity and was a
Analytical performance of a novel next generation sequencing assay for Myeloi...Thermo Fisher Scientific
To support clinical and translational research into precision oncology strategies for myeloid cancers, a next-generation sequencing (NGS) assay was developed to detect common and relevant somatic alterations. To define gene targets that were recurrently altered in myeloid cancers and relevant for clinical and translational research, an extensive survey of investigators at hematology oncology research labs was performed.
1) The document discusses the Halsted and Fisher hypotheses regarding breast cancer treatment. The Halsted hypothesis viewed breast cancer as spreading in an orderly manner from the breast to lymph nodes to distant sites, supporting radical mastectomy. The Fisher hypothesis viewed breast cancer as a systemic disease at diagnosis.
2) Recent evidence from NSABP trials suggests local therapy and local recurrence may affect survival outcomes, challenging the Fisher hypothesis. Patients who experienced local recurrence had higher risks of distant disease and mortality. Improved local control with radiotherapy was associated with decreased breast cancer deaths.
3) The evidence indicates that both local and systemic factors play a role in breast cancer, supporting an approach that considers both.
This document describes the characterization of a new head and neck squamous cell carcinoma (HNSCC) cell line called USC-HN2. USC-HN2 was established from a patient with recurrent oral cavity cancer. Characterization showed USC-HN2 has properties typical of aggressive oral HNSCC, including expression of markers like EGFR, CD44v6, and FABP5. Testing revealed USC-HN2 strongly induces regulatory T cells and myeloid-derived suppressor cells in vitro, suggesting an immunosuppressive phenotype. Comparison to another HNSCC cell line, SCCL-MT1, showed both lines have robust cytokine production and immune cell induction, making them useful models for
In Silico Prescription of Anticancer Drugs Reveals Targeting OpportunitiesNuria Lopez-Bigas
Large efforts dedicated to sequence thousands of tumor genome/exomes are expected to lead to significant improvements of precision cancer medicine. However, high inter-tumor heterogeneity is a major obstacle in the road to develop an arsenal of targeted cancer drugs to treat most cancer patients. Therefore, it is critical to understand the current scope of anti-cancer targeted drugs for different tumor types in order to use them with the highest efficacy, and to define priorities for the development of new ones. We have developed a novel methodology to interpret the genomes of a cohort of tumor samples and to assess their therapeutic opportunities. Starting with somatic mutations detected across the cohort, the methodology identifies the driver genes, highlights those that dominate the clonal landscape of the tumors and determines their mode of action. It then does an in-silico prescription of approved and candidate targeted drugs to each patient in the cohort. The application of this approach to a cohort of 6795 cancer samples of 28 different tumor types showed that the fraction of patients that could benefit from prescribed FDA-approved drugs is strikingly small. Nevertheless, it improves significantly if repurposing opportunities are taken into consideration, with large differences between tumor types. In addition, we identify 80 therapeutically unexploited cancer genes, tightly bound by pre-clinical small molecules or potentially suitable for molecule binding. The resource created with this analysis is also intended to provide interpretation of newly sequenced cancer genomes and to design pan-cancer and tumor type specific sequencing panels for efficient early cancer detection and clinical insight.
More details at http://www.intogen.org
kSORTTM is a non-invasive blood test that analyzes gene expression to assess immune risk in kidney transplant patients. The analytical performance of kSORTTM was validated in an independent clinical laboratory. Accuracy was high, with 87% agreement between kSORTTM results and biopsy results. Precision studies showed 15% variability in quantitative scores and 94% consistency in qualitative results over multiple runs. Sensitivity was 100% and specificity was 96% when excluding indeterminate results. Validation demonstrates that kSORTTM is analytically sound for clinical use in monitoring transplant patients.
This document discusses genomic oncology and personalized medicine, using lung cancers as a model. It summarizes several key technologies that enable genomic oncology like cDNA microarrays, array CGH, and next generation sequencing. It provides examples of how these technologies have been used to classify cancers like diffuse large B-cell lymphoma and myelodysplastic syndrome, and identify genetic mutations that can guide targeted therapies for cancers like EGFR-mutated lung cancer.
NSA Diagnostic Laboratory has been operating since 1958, founded by Prof. Nasseh Amin. NSA is considered as one of the most advanced labs in Egypt. Maintaining personalized services for its stakeholders, as well as the main role of the lab "Diagnosis"
NSA Diagnostic Laboratory operates through two different segments.
Firstly, a group of stand-alone labs located at prime locations all over Egypt, with the latest and up to date equipments.
Secondly, being the backbone of well reputed hospitals and some polyclinics where NSA is the lab that is responsible for all medical testing there, serving all our patients with class A quality.
Our main focus is delivering quality care and with Cost-value return. NSA plays a key role in improving the health of many Egyptians, by providing access to quality service for more than 200,000 patients annually.
This curriculum vitae outlines the educational background and professional experience of Dr. Waleed O. Arafat. He received his M.B.B.Ch. in 1989 from the University of Alexandria Faculty of Medicine in Egypt and his PHD in clinical oncology in 2002. He has held positions at several institutions and currently serves as an assistant professor in clinical oncology at the University of Alexandria. His areas of research interest include translational cancer research, gene therapy, and radiotherapy. He has over 30 publications in peer-reviewed journals and has presented his research findings at numerous conferences.
Identification of cancer drivers across tumor typesNuria Lopez-Bigas
Thousands of tumor genomes/exomes are being sequenced as part of the International Cancer Genome Consortium (ICGC), The Cancer Genome Atlas (TCGA) and other initiatives. This opens the possibility to have, for the first time, a comprehensive picture of mutations, genes and pathways involved in the cancer phenotype across tumor types. We have developed computational methods able to identify signals of positive selection in the pattern of tumor somatic mutations, which point to genes and pathways directly involved in the development of the tumors. We have applied these approaches to 3025 tumors from 12 different cancer types of the TCGA Pan-Cancer project, identifying 291 high-confidence cancer driver genes acting on those tumors (Tamborero et al 2013). We have also developed IntOGen-mutations (http://www.intogen.org/mutations), a novel web platform for cancer genomes interpretations, which analyses not only TCGA pan-cancer data but all mutation data from ICGC and other initiatives. The resource allows users to identify driver mutations, genes and pathways acting on more than 6000 tumors originated in 17 different cancer sites and to analyze newly sequence tumor genomes. Among the novel cancer drivers identified there are chromatin regulatory factors and splicing factors, which are emerging as important genes in cancer development and are regarded as interesting candidates for novel targets for cancer treatment. In my talk I will summarize all these recent findings.
More info: http://bg.upf.edu/blog/2013/10/my-slides-on-identification-of-cancer-drivers-across-tumor-types/
This document discusses the use of radioisotopes, particularly iodine isotopes, in medical applications like diagnosis and treatment of thyroid disorders and cancers. It describes techniques like radioimmunoassay (RIA), radioimmunolocalization (RIL), radioimmunotherapy, and thyroid scanning that use radioisotopes. RIA uses radioisotope-labeled antigens or antibodies to detect substances in the body, while RIL and radioimmunotherapy use labeled antibodies to detect and treat tumors. Thyroid scanning uses various iodine isotopes to evaluate thyroid function and detect abnormalities.
This is a history of that my www.alphataumedical.com platform technology that is the most effective therapy for all solid tumor with the bonuses of no, there cannot be, side effects, dissolving tumors in days and its alpha particles uniquely are the only type of radiation that cuts both helices of the tumor’s DNA.
The Presence and Persistence of Resistant and Stem Cell-Like Tumor Cells as a...QIAGEN
Epithelial ovarian cancer is the fifth leading cause of cancer-related deaths of women in the United States and Europe and ranks as the second most common type of gynecological malignancy. Most cases are diagnosed in advanced stages and although the response rates to platinum-based chemotherapy are high, the majority of patients nevertheless have poor survival rates. Although the reasons for these poor outcomes are likely to be multifactorial, one particular area of interest has recently focused on hematogenous tumor cell dissemination that has been shown to originate from disseminated tumor cells (DTCs) in the bone marrow (BM) and circulating tumor cells (CTCs) in the blood. Here, we demonstrate that the negative prognostic impact of CTCs and DTCs arise from specific cellular phenotypes and are associated with platinum-resistance and stem cell-associated proteins.
The document discusses next generation sequencing and its applications in cancer research. It notes that NGS allows studying genetic variations at the individual base level in a fast and affordable manner. The document also distinguishes between driver mutations, which confer a growth advantage to cancer cells, and passenger mutations, which do not directly contribute to cancer. Driver mutations can inactivate tumor suppressor genes or activate oncogenes.
A new assay for measuring chromosome instability (CIN) and identification of...Enrique Moreno Gonzalez
This document describes a new assay for measuring chromosome instability (CIN) using a human artificial chromosome (HAC) carrying a fluorescent marker. The assay allows quantification of HAC loss after drug treatment via flow cytometry. Several known anti-mitotic drugs were tested and found to increase HAC loss rates to varying degrees, with microtubule-stabilizing drugs taxol and peloruside A showing the highest increases in CIN. This new assay provides a simple and efficient way to screen drugs and identify those that elevate CIN, with the goal of developing new cancer therapies targeting chromosomally unstable tumors.
1. The document discusses studies comparing adjuvant radiation therapy to salvage radiation therapy for prostate cancer patients with adverse pathological features after radical prostatectomy.
2. The EORTC 22911 trial randomized over 1000 patients to either observation or adjuvant radiation and found significantly improved biochemical progression-free survival with adjuvant radiation.
3. Other large trials including SWOG and ARO 96-02 also found benefits to adjuvant radiation in reducing risks of biochemical recurrence, distant metastases and death from prostate cancer.
Cancer Care Delivery Gaps in India based on EY ReportsPuneet Seth
This document discusses gaps in cancer care delivery in central India and proposes establishing a comprehensive cancer care center. It notes that cancer cells can reproduce rapidly, growing from one million to one billion cells in as little as 6 weeks. There are key barriers to timely diagnosis and treatment of cancer as well as a lack of adequate radiation therapy infrastructure and oncologists, especially outside of major metro areas. A comprehensive cancer care center could help address these issues and improve access to high quality cancer treatment.
The document summarizes research using chick embryo models to study cancer metastasis. It describes several advantages of the chick embryo model, including its ability to support rapid growth of xenografted human tumor cells. Several chick embryo cancer models are outlined, including models for spontaneous metastasis, analyzing tumor cell interactions with vasculature, and studying invasion and extravasation. Examples are given of studies using these models to analyze tumor growth and metastasis of various cancer cell lines and effects of potential therapeutics.
Knocking on the clinic door of precision medicine Yoon Sup Choi
1. Recent advances in precision oncology are based on next-generation sequencing (NGS) which has improved precision medicine for cancer patients.
2. Technologies like NGS have enabled more precise cancer diagnosis and treatment by identifying genetic mutations in tumors that can be targeted by specific therapies.
3. However, tumor heterogeneity, where different mutations exist between and within tumors, remains a challenge as it can cause resistance to targeted therapies.
In the current study, we have experimentally and comparatively
investigated and compared malignant human cancer cells and tissues before and aft er irradiating of synchrotron radiation using Lase Spectroscopy, Laser–Induced Breakdown Spectroscopy (LIBS) and Laser-Induced Plasma Spectroscopy (LIPS). It is clear that malignant human cancer cells and tissues have gradually transformed to benign human cancer cells and tissues under synchrotron radiation with the passage of time
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
Preliminary Study on Monitoring Drug Resistance of Colon Cancer with Intravox...semualkaira
The current study investigated the role of intravoxel incoherent motion-DWI (IVIM-DWI) in evaluating drug
resistance in colon cancer xenografts and explored possible biomarkers.
The document summarizes a study that investigated the effects of synchrotron radiation on malignant and benign human cancer cells and tissues over time using infrared photo dissociation spectroscopy and infrared correlation table spectroscopy. The study found that malignant human cancer cells and tissues gradually transformed into benign human cancer cells and tissues when exposed to synchrotron radiation, as shown in Figures 1 and 2. References 116 studies are cited that relate to the use of spectroscopy and nanoparticles to study and treat cancer.
The document discusses targeted therapy in colorectal cancer, noting that it is the third most common cancer worldwide and outlines recent developments in targeted therapies for specific molecular alterations like BRAF V600E mutations, HER2 amplifications, and KRAS G12C mutations, highlighting studies demonstrating improved outcomes with combinations of targeted agents and chemotherapy.
Rodger - Prostate cancer mortality outcomes and patterns of primary treatment...Cancer Council NSW
This document summarizes a study examining differences in prostate cancer mortality and primary treatment between Aboriginal and non-Aboriginal men in New South Wales, Australia. The study found that Aboriginal men were 49% more likely to die of prostate cancer within 5 years of diagnosis compared to non-Aboriginal men, even after adjusting for demographic factors, stage at diagnosis, health access and comorbidities. Aboriginal men were also less likely to receive curative surgery (prostatectomy) for localised or regional prostate cancer. A medical record review of 87 Aboriginal men provided more detailed information on staging and treatment, finding that of those diagnosed with localised disease, 38% had a prostatectomy and radiotherapy, 29% had radiotherapy only, and
This document describes a study that used pyrolysis gas chromatography differential mobility spectrometry (Py-GC-DMS) to analyze serum samples from mantle cell lymphoma (MCL) patients in order to predict clinical outcomes. The study analyzed samples from 21 MCL patients, dividing them into groups with good or poor outcomes based on survival time. The Py-GC-DMS technique was used to generate ionization signatures from the samples. A multivariate algorithm was then applied to the signature data to predict the probability of good or poor outcome. The results provide a proof of concept that Py-GC-DMS could predict clinical outcomes for diseases like MCL with high accuracy, suggesting potential for this technique in medical applications.
Mutations of KRAS that Have a Profound Impact on Cancer Genomic Medicine Curr...ijtsrd
The rat sarcoma viral oncogene homolog RAS family of closely related oncogenes KRAS, HRAS, and NRAS are the most frequently mutated drivers of malignant transformation. Although the RAS family genes were discovered as human significant tumor genes 40 years ago, the RAS proteins have proved to be challenging targets in anti tumor drug discovery sotorasib was only approved as the first direct inhibitor of a RAS protein for clinical use in 2021. The downstream signaling pathway of the epidermal growth factor receptor EGFR mainly. EGF selectively binds to EGFR and triggers the receptor to form a dimer that activates RAS. RAS transmits signals from activated trans membrane receptor EGFR to effectors in the B raf proto oncogene BRAF mitogen activated protein kinase MEK extracellular signal regulated kinase ERK signaling pathway in the cytoplasm. The status of RAS proteins is a negative predictive biomarker for anti epidermal growth factor receptor EGFR therapy in metastatic colon cancer. Our studies revealed that splicing caused by the RAS mutations, which were considered oncogenic, generates unfunctional RAS family. Especially, Kirsten Rat Sarcoma KRAS silent variants are of concern to be a serious problem in genomic cancer medicine. Takuma Hayashi | Nobuo Yaegashi | Ikuo Konishi "Mutations of KRAS that Have a Profound Impact on Cancer Genomic Medicine Currently Being Pursued" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-1 , February 2023, URL: https://www.ijtsrd.com/papers/ijtsrd52703.pdf Paper URL: https://www.ijtsrd.com/medicine/other/52703/mutations-of-kras-that-have-a-profound-impact-on-cancer-genomic-medicine-currently-being-pursued/takuma-hayashi
Case Report Writing Services | Medical Case Study Report WritingPubrica
The administration of a neuromuscular blocking agent (NMBA) facilitates patient ventilation during surgery, prevents involuntary movements by the patient and enhances surgical exposure. Rucuronium, an aminosteroid and cisatacurium, a benzylisoquinone compound are two commonly used neuromuscular blocking agents with different molecular and pharmacological properties.
Read more @ https://pubrica.com/insights/sample-work/a-case-study-on-the-effectiveness-of-recovery-for-patients-underwent-laparoscopic-weight-loss-surgery/
Visit us @ https://pubrica.com/services/research-services/case-report-writing/
Development of pancreatic cancer organoid model for studying immune response ...TÀI LIỆU NGÀNH MAY
Để xem full tài liệu Xin vui long liên hệ page để được hỗ trợ
: https://www.facebook.com/thuvienluanvan01
HOẶC
https://www.facebook.com/garmentspace/
https://www.facebook.com/thuvienluanvan01
https://www.facebook.com/thuvienluanvan01
tai lieu tong hop, thu vien luan van, luan van tong hop, do an chuyen nganh
This document reviews the evidence for managing locally advanced rectal cancers. It discusses how treatment has evolved from surgery alone to incorporating neoadjuvant radiation and chemotherapy. Neoadjuvant treatment has been shown to improve local control and survival compared to postoperative or adjuvant treatment. Achieving a pathological complete response after neoadjuvant therapy is associated with better long-term outcomes. Researchers have explored intensifying neoadjuvant treatment and increasing the interval before surgery to improve response rates. Accurately identifying patients who could avoid surgery through a "watch and wait" strategy depends on improved radiological assessment of tumor response.
This article compared robot-assisted vasovasostomy (RAVV) and robot-assisted vasoepididymostomy (RAVE) to traditional microsurgical vasovasostomy (MVV) and microsurgical vasoepididymostomy (MVE) using data from 123 cases. RAVV achieved a higher patency rate of 96% compared to 80% for MVV. RAVV also had a shorter median operative duration of 90 minutes versus 120 minutes for MVV. Additionally, the sperm count recovery was significantly higher for RAVV than RAVE. The authors concluded that robotic techniques may offer advantages over traditional microsurgery for vasectomy reversal based on improved outcomes. However, further
Presentación auspiciada por Janssen en el marco del 5to congreso de actualización de Hematología y Oncología, 26.08.2017, Centro de Convenciones, Blue Garden, Barranquilla
Similar to American Journal of Nanotechnology & Nanomedicine (20)
A 5-year old boy, with an established diagnosis of a topic
dermatitis, previously treated by topical corticosteroids and emollient cream with a good improvement, developed widespread papules on his legs, hands and forearm that appeared 5 months ago.
Methods: Retrospectively, the file records of the patients who underwent sleeve gastrectomy were examined. Demographic features, Body Mass Index (BMI), the mouth opening, Mallampati score, thyromental distance, sternomental distance, neck circumference measurements and videolaryngoscopic examination results were recorded Results: In a total of 140 consecutive patients (58 male, 82 female) were included in the study. The mean age of the study participants was 35.40 ± 9.78 and the mean BMI of the patients was 44.33 ± 7.52 kg/m2
. The mean mouth opening of the patients was 4.82 ± 0.54 cm
and the mean neck circumference was 43.52 ± 4.66 cm. The mean thyromental distance was 8.02 ± 1.00 cm and the mean sternomental distance was16.58 ± 1.53 cm. Difficult intubation was determined in 8 (5.7%) patients. In logistic regression analysis, age (p : 0.446), gender (p : 0.371), BMI (p : 0.947), snoring (p : 0.567), sleep apnea (p : 0.218), mouth opening (p : 0.687), thyromental distance (p :0.557), sternomental (p : 0.596) and neck circumference (p : 0.838) were not the independent predictors of difficult intubation. However, Mallampati score (p : 0.001) and preoperative direct laryngoscopy findings (p : 0.037) performed in outpatient clinic were the significant
predictors of difficult intubation. Interestingly, all patients with grade 4 laryngoscopy findings had difficult intubation.
Introduction: Laparoscopic surgery has been performed in Mexico since 1989, but no reports about training tendencies exist. We conducted a national survey in 2015, and here we report the results concerning training characteristics during the surgical residence of the respondents. Materials and Methods: A prospective study was conducted through a survey questioning demographic data, laparoscopic training during pre and post surgical residency and other of areas of laparoscopic practice. The sample was calculated and survey piloted before
application. Special interest in this report was placed on type and quality of training received. Data are reported in percentages.
Heterotopic Ossification (HO) is defined as pathological bone formation at locations where bone normally does not exist. The
presence of HO has been found to be a rare complication after stroke in several studies, whereas there are only sporadic references relating HO to Cerebral Palsy (CP) and few for CP and stroke. No effective treatment for HO has yet been found, whereas the cellular and molecular mechanisms have not been completely understood. Therefore, increased awareness among physicians is required, as a challenge for early diagnosis and treatment. A case of a male patient with CP, who developed HO on the paretichip joint following an ischemic stroke is presented.
Objectives: To assess the practice of food hygiene and safety, and its associated factors among street food vendors in urban areas of Shashemane, West Arsi Zone, Oromia Ethiopia, 2019.
Methods: Cross-sectional study design was applied from December 28, 2019 to January 27, 2020. Data was collected from 120 food handlers, which were selected by purposive sampling techniques. Information was gathered from interview and field observation by conducting food safety survey and using questionnaires via face to face interview. The collected data was entered using Epi Data 3.1 and finally, it was analyzed using SPSS VERSION 20.
A Division I football player experienced acute posterior leg pain while playing. An ultrasound examination revealed an unusual injury - a complete rupture of the plantaris tendon mid-substance. This type of isolated plantaris tendon injury has rarely been reported. Ultrasound was useful for diagnosis and guided rehabilitation by monitoring healing over time. The athlete was able to return to full competition within 3 weeks through a progressive rehabilitation program focused on restoring range of motion and strength. This case suggests isolated plantaris tendon injuries may allow for faster return to play than other potential causes of posterior leg pain.
Type 1 Diabetes (T1D), is a severe disease, representing 5-10% of all reported cases of diabetes worldwide. Fulminant Type 1 Diabetes Mellitus (FT1D) is a subtype of type 1 diabetes mellitus that is largely characterized by the abrupt onset of Diabetic Ketoacidosis (DKA) and severe hyperglycemia without insulin defi ciency. Viral infections have been hypothesized to play a major role in the pathogenesis of Fulminant Type 1 Diabetes Mellitus (FT1D) through the complete and rapid destruction of pancreatic beta cells. Coxsackie viral infection has been detected in islets of 50% of the pancreatic tissue recovered from recent-onset Type 1 Diabetes (T1D) patients. In this report we have highlighted a case where the patient developed a Group B Coxsackie virus infection culminating in the development of Fulminant Type 1 Diabetes Mellitus (FT1D).
Methods: Cercariae are released by infected water snails. To determine the occurrence of cercariae-emitting snails in SchleswigHolstein, 155 public bathing places were visited and searched for fresh water snails. Family and genus of the collected snails were determined and the snails were examined for the shedding of cercariae, using a standard method and a newly developed method.
Objective: To generate preliminary information about of enteroviruses and Enterovirus 71 (EV71) in patients with aseptic meningitis in Khartoum State, Sudan.
Method: Cerebrospinal fluid specimens were collected from 89 aseptic meningitis patients from different Khartoum Hospitals
(Mohammed Alamin Hamid Hospital, Soba Teaching Hospital, Omdurman Military Hospital, Alban Gadeed Teaching Hospital and Police Hospital) within February to May 2015. Among these 89 patients, 43 (48%) were males and 46 (52%) were females. The patient’s age ranged between 1 day and 30 years old. The collected specimens were assayed to detect enteroviruses and EV71 RNA using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) technique
Femoral hernias, comprise 2% to 4% of all hernias in the inguinal region, and occur most commonly in women. Th ey present typically with a mass below the level of the inguinal ligament. The sac may contain preperitoneal fat, omentum, small bowel, or other structures and have a high rate of incarceration and strangulation due to the small size of the hernia neck orifice, requiring emergency surgery. We present the case of a 54-year-old female patient with intestinal occlusion due to incarcerated femoral hernia, repaired by laparoscopic approach, that gave the patient the opportunity to attend her daughter’s wedding the same day.
Small Supernumerary Marker Chromosome (sSMC) is a rare genetic condition marked by the presence of an extra chromosome to the 46 human chromosomes. This case report describes a 4 year old child with SSMC on the 46th chromosome. The child presented with delayed speech and language development, seizures and mild developmental delay. Speech and Language evaluation was carried out and management options are discussed.
A catheter is a thin tube made from medical grade materials that serve a broad range of functions, but mainly catheters are medical devices that can be inserted in the body to treat disease or perform surgical procedures. Catheters have been inserted into body cavities, ducts, or vessels to allow for drainage, administration of therapeutic fluids or gases, operational access for surgery. Catheters help perform tasks in various systems such as cardiovascular, urological, gastrointestinal, neurovascular, and ophthalmic systems. A dataset of 12 patients with varying “weights” and “heights” was recorded along with the lengths of their catheter tubes. This data set was found from two revered statistical textbooks on linear regression and the Department of Scientific Computing at Florida State University. This data set was not able to be linked to any particular clinical or experimental research studies, but the data set can be used to help catheter manufacturers and medical professionals better decide on what particular catheter lengths to use for patients knowing only their height & weight. These research insights could be helpful to healthcare professionals that have patients with incomplete or no healthcare records
to decide what catheter length to use. The main investigative inquiry that needed to be answered was how does patient weight & height influence catheter length together and separately? We conducted linear regression and other statistical analysis procedures in R program & Microsoft Excel and discovered that this data exhibited a quality called multi collinearity. With multi collinearity, all predictors (2 or more
independent variables) are not significant in an all encompassing linear aggression, but the predictors might be significant in their own individual linear regressions. Individual linear regression analyses were conducted for both patient height & weight to see how much they both contribute to varying catheter length. Patient weight was found to be more impatful than patient height in relationship to catheter length, even though height and weight are a classical example of multi collinearity predictors.
Bovine mastitis has a negative impact through economic losses in the dairy sector across the globe. A cross sectional study was carried out from September 2015 to July 2016 to determine the prevalence of bovine mastitis, associated risk factors and isolation of major causative bacteria in lactating dairy cows in selected districts of central highland of Ethiopia. A total of 304 lactating cows selected randomly from five districts were screened by California Mastitis Test (CMT) for subclinical mastitis. Based on CMT result and clinical examination, over all prevalence of mastitis at cow level was 70.62% (214/304).
Two hundred fourteen milk samples collected from CMT positive cows were cultured for isolation of major causative bacteria. From 214 milk samples,187 were culture positive and the most prevalent isolates were Staphylococcus aureus 42.25% (79/187) followed by Streptococcus agalactiae 14.43%
(27/187). Other bacterial isolates were included Coagulase Negative Staphylococcus species 12.83% (24/187), Streptococcus dysgalactiae 5.88% (11/187), Escherichia coli 13.38% (25/187) and Entrococcus feacalis 11.23% (21/187) were also isolated. Moreover, age, parity number, visible teat abnormalities,husbandry practice, barn fl oor status and milking hygiene were considered as risk factors for the occurrence of bovine mastitis and they were found significantly associated with the occurrence of mastitis (p < 0.05). The findings of this study warrants the need for strategic approach including dairy extension that focus on enhancing dairy farmers’ awareness and practice of hygienic milking, regular screening for subclinical mastitis, dry cow therapy and culling of chronically infected cows.
A 36-year-old female developed right upper quadrant pain and nausea after taking the herbal supplement kratom for two weeks to manage back pain. Laboratory tests showed elevated liver enzymes. A liver biopsy ruled out other causes and determined she had drug-induced liver injury from kratom use. Her symptoms and liver enzymes gradually returned to normal over six weeks after stopping kratom. The case report discusses kratom's potential for hepatotoxicity and advises clinicians to consider its effects on patient health.
The assessment, diagnosis and treatment of critically ill patients is extremely challenging. Patients often deteriorate whilst being
reviewed and their rapidly changing pathophysiology barrages healthcare professionals with new data. Furthermore, comprehensive assessments must be postponed until the patient has been stabilised. So, important data and interventions are often missed in the heat of the moment. In emergency situations, suboptimal management decisions may cause signifi cant morbidity and mortality. Fortunately, standardisation and careful design of documentation (i.e. proformas and checklists) can enhance patient safety. So, I have developed a series of checklist proformas to guide the assessment of critically ill patients. These proformas also promote the systematic recording and presentation of information to facilitate the retrieval of the precise data required for the management for critically ill patients. The proformas have been modifi ed extensively over the last twenty years based on my personal experience and extensive consultation with colleagues in several world-renowned centres of excellence. The proformas were originally developed for use in the intensive therapy unit
or high dependency unit. However, they have been adapted for use by outreach teams reviewing patients admitted outside of critical care areas. The use of these tools can direct eff orts to provide appropriate organ support and provides a framework for diagnostic reasoning.
This review article discusses microvascular and macrovascular disease in systemic hypertension. It summarizes that:
1) Cardiac imaging plays a crucial role in risk stratifying hypertensive patients and identifying management strategies by properly diagnosing microvascular and coronary artery disease.
2) The nitric oxide synthase (eNOS) G298 gene allele may be a marker for microvascular angina in hypertensive patients, as studies have found it to be more prevalent in hypertensive patients with chest pain and reversible myocardial defects but normal coronary arteries.
3) Both structural changes like capillary rarefaction and functional changes like endothelial dysfunction can cause microvascular dysfunction and angina in hypertensive individuals in the absence of
This study characterized dengue infections in Pakistan by analyzing hematological and serological markers in 154 suspected dengue cases and 146 control patients with other febrile illnesses. NS1 antigen was detected in 55% of dengue cases, IgM antibodies in 30%, and both in 15%. Control groups primarily had malaria (71%) and enteric fever (20%). Hematological markers (platelet count, hematocrit, WBC) measured before and after treatment showed significant differences for platelet count and hematocrit but not WBC count between the groups. Analysis of clinical symptoms and serological/hematological markers helps diagnose dengue, assess prognosis, and inform prevention efforts to reduce morbidity, mortality and spread of the disease.
Researchers from Utrecht recently published yet another paper on the use of Magnetic Resonance Imaging (MRI)demonstrating an additional failed attempt to understand the importance of qualitative versus quantitative imaging, and anatomic versus physiologic imaging. Th e implications of this failure here cannot be overstated.
Introduction: Stroke is an even more dramatic major public health problem in young people. Goal of the study: Contribute to the knowledge of strokes in young people. Methodology: This was a retrospective study carried out over a period of 02 years (January 2017 to December 2018) including the files of patients aged 18 to 49 years hospitalized for any suspected case of stroke in the Neurology department of the University Hospital
Center of the Sino-Central African Friendship (CHUSCA) of Bangui.
Background: This report describes a unique case of a patient that developed psychotic symptoms believed to be secondary
to a tentorial meningioma with associated hydrocephalus. These psychotic symptoms subsequently abated with placement of a
ventriculoperitoneal shunt. Case description: 60-year-old female was admitted to an inpatient psychiatric facility on a psychiatric involuntary commitment petition due to progressive paranoia, homicidal ideation and psychosis. The work up showed a calcified six cm tentorial meningioma with associated hydrocephalus. The patient initially rejected treatment but later became amenable to placement of Ventriculoperitoneal Shunt
(VPS).
More from SciRes Literature LLC. | Open Access Journals (20)
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
One health condition that is becoming more common day by day is diabetes.
According to research conducted by the National Family Health Survey of India, diabetic cases show a projection which might increase to 10.4% by 2030.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Our backs are like superheroes, holding us up and helping us move around. But sometimes, even superheroes can get hurt. That’s where slip discs come in.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by...Donc Test
TEST BANK For Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler, Verified Chapters 1 - 33, Complete Newest Version Community Health Nursing A Canadian Perspective, 5th Edition by Stamler Community Health Nursing A Canadian Perspective, 5th Edition TEST BANK by Stamler Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Study Guide Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Stuvia Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Studocu Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Test Bank For Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Pdf Download Course Hero Community Health Nursing A Canadian Perspective, 5th Edition Answers Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Ebook Download Course hero Community Health Nursing A Canadian Perspective, 5th Edition Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Studocu Community Health Nursing A Canadian Perspective, 5th Edition Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Chapters Download Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Pdf Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Study Guide Questions and Answers Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Ebook Download Stuvia Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Questions Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Studocu Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Quizlet Community Health Nursing A Canadian Perspective, 5th Edition Test Bank Stuvia
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
2. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 002
Grazing-Incidence Small- Angle Neutron Scattering (GISANS),
X-Ray Diffraction (XRD), Powder X-Ray Diffraction (PXRD),
Wide-Angle X-Ray Diffraction (WAXD), Grazing- Incidence
X-Ray Diffraction (GIXD) and Energy-Dispersive X-Ray Diffraction
(EDXRD). It is clear that malignant human cancer cells and tissues
have gradually transformed to benign human cancer cells and tissues
under synchrotron radiation and anti-cancer Nano drugs delivery
with the passing of time (Figures 1-13) [1-141].
It can be concluded that malignant human cancer cells and tissues
have gradually transformed to benign human cancer cells and tissues
under synchrotron radiation and anti-cancer Nano drugs delivery
with the passing of time (Figures 1-13) [1-141].
EDITORIAL
In the current study, we have experimentally and comparatively
investigated and compared malignant human cancer cells and
tissues before and after irradiating of synchrotron radiation using
Small-Angle X-Ray Scattering (SAXS), Ultra-Small Angle X-Ray
Scattering (USAXS), Fluctuation X-Ray Scattering (FXS), Wide-
Angle X-Ray Scattering (WAXS), Grazing- Incidence Small-Angle
X-Ray Scattering (GISAXS), Grazing-Incidence Wide-Angle X-Ray
Scattering (GIWAXS), Small-Angle Neutron Scattering (SANS),
(a)
(b)
Figure 1: Small-Angle X-Ray Scattering (SAXS) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
(a)
(b)
Figure 2: Ultra-Small Angle X-Ray Scattering (USAXS) analysis of malignant
human cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
(a)
(b)
Figure 3: Fluctuation X-Ray Scattering (FXS) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1–141].
(a)(A)
(B)
Figure 4: Wide-Angle X-Ray Scattering (WAXS) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
3. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 003
(a)
(b)
Figure 5: Grazing-Incidence Small-Angle X-Ray Scattering (GISAXS) analysis of
malignant human cancer cells and tissues (a) before and (b) after irradiating of
synchrotron radiation in transformation process to benign human cancer cells
and tissues with the passing of time [1-141].
(a)
(b)
Figure 6: Grazing-Incidence Wide-Angle X-Ray Scattering (GIWAXS) analysis of
malignant human cancer cells and tissues (a) before and (b) after irradiating of
synchrotron radiation in transformation process to benign human cancer cells
and tissues with the passing of time [1-141].
(a)
(b)
Figure 7: Small-Angle Neutron Scattering (SANS) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
(a)
(b)
Figure 8: Grazing-Incidence Small-Angle Neutron Scattering (GISANS) analysis
of malignant human cancer cells and tissues (a) before and (b) after irradiating
of synchrotron radiation in transformation process to benign human cancer
cells and tissues with the passing of time [1-141].
(a)
(b)
Figure 9: X-Ray Diffraction (XRD) analysis of malignant human cancer cells
and tissues (a) before and (b) after irradiating of synchrotron radiation in
transformation process to benign human cancer cells and tissues with the
passing of time [1-141].
(a)
(b)
Figure 10: Powder X-Ray Diffraction (PXRD) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
4. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 004
REFERENCES
1. Alireza H, Brown C. Study of composition and morphology of Cadmium Oxide
(CdO) nanoparticles for eliminating cancer cells. Journal of Nanomedicine
Research. 2015; 2. https://goo.gl/M5VxKu
2. Alireza H, Brown C. Study of surface morphological, phytochemical and
structural characteristics of Rhodium (iii) Oxide (Rh2
O3
) nanoparticles.
International Journal of Pharmacology. Phytochemistry and Ethnomedicine.
2015; 1: 15-19. https://goo.gl/XszRPr
3. Alireza H. An experimental biospectroscopic study on seminal plasma in
determination of semen quality for evaluation of male infertility. Int J Adv
Technol. 2016; 7. https://goo.gl/AVfecW
4. Alireza H. Extraction and preconcentration of n-tolyl-sulfonyl-phosphoramid-
saeure-dichlorid as an anti-cancer drug from plants: a pharmacognosy study.
J Pharmacogn Nat Prod. 2016; 2: 103. https://goo.gl/BYjik9
5. Alireza H. A thermodynamic study on hydration and dehydration of DNA and
RNA amphiphile complexes. J Bioeng Biomed Sci. 2016; 6. https://goo.gl/
W4dhyd
6. Alireza H. Computational studies on molecular structures and carbonyl and
ketene groups’ effects of singlet and triplet energies of Azidoketene O=C=CH-
NNN and Isocyanatoketene O=C=CH-N=C=O. J Appl Computat Math. 2016;
5: 142. https://goo.gl/ijLKon
7. Alireza H. Study of irradiations to enhance the induces the dissociation of
hydrogen bonds between peptide chains and transition from helix structure to
random coil structure using ATR-FTIR, Raman and 1
HNMR Spectroscopies.
J Biomol Res Ther. 2016; 5: 146. https://goo.gl/RfnUaL
8. Alireza H. Future prospects of point fluorescence spectroscopy, fluorescence
imaging and fluorescence endoscopy in Photodynamic Therapy (PDT) for
cancer cells. J Bioanal Biomed. 2016; 8: 135. https://goo.gl/kfaFhn
9. Alireza H. A bio-spectroscopic study of DNA density and color role as
determining factor for absorbed irradiation in cancer cells. Adv Cancer Prev.
2016; 1: 102. https://goo.gl/g53MXQ
10. Alireza H. Manufacturing process of solar cells using Cadmium Oxide (CdO)
and Rhodium (iii) Oxide (Rh2
O3
) nanoparticles. J Biotechnol Biomater. 2016;
6: 125. https://goo.gl/YVzNj8
11. Alireza H. A novel experimental and computational approach to
photobiosimulation of telomeric DNA/RNA: a biospectroscopic and
photobiological study. J Res Development. 2016; 4: 144. https://goo.gl/
DBxm6h
12. Alireza H. Biochemical and pharmacodynamical study of microporous
molecularly imprinted polymer selective for vancomycin, teicoplanin,
oritavancin, telavancin and Dalbavancin binding. Biochem Physiol. 2016; 5:
146. https://goo.gl/tzKyVK
13. Alireza H. Anti-cancer effect of UV irradiation at presence of Cadmium Oxide
(CdO) nanoparticles on DNA of cancer cells: a photodynamic therapy study.
Arch Cancer Res. 2016; 4: 1. https://goo.gl/Nt44cC
14. Alireza H. Biospectroscopic study on Multi-Component Reactions (MCRs)
in two a-type and b-type conformations of nucleic acids to determine ligand
binding modes, binding constant and stability of nucleic acids in Cadmium
Oxide (CdO) nanoparticles-nucleic acids complexes as anti-cancer drugs.
Arch Cancer Res. 2016; 4: 2. https://goo.gl/73MK8o
15. Alireza H. Simulation of temperature distribution of DNA/RNA of human
cancer cells using time-dependent bio-heat equation and Nd: YAG Lasers.
Arch Cancer Res. 2016; 4: 2. https://goo.gl/BTx27w
16. Alireza H. Quantitative Structure-Activity Relationship (QSAR) approximation
for Cadmium Oxide (CdO) and Rhodium (III) Oxide (Rh2
O3
) nanoparticles as
anti-cancer drugs for the catalytic formation of proviral DNA from Viral RNA
using multiple linear and non-linear correlation approach. Ann Clin Lab Res.
2016; 4: 1. https://goo.gl/9hNJ7T
17. Alireza H. Biomedical study of cancer cells DNA therapy using laser
irradiations at presence of intelligent nanoparticles. J Biomedical Sci. 2016;
5: 2. https://goo.gl/GyvHSE
18. Alireza H. Measurement the amount of vitamin D2 (Ergocalciferol), vitamin D3
(Cholecalciferol) and absorbable Calcium (Ca2+
), Iron (II) (Fe2+
), Magnesium
(Mg2+
), Phosphate (PO4-
) and Zinc (Zn2+
) in apricot using High-Performance
Liquid Chromatography (HPLC) and spectroscopic techniques. J Biom
Biostat. 2016; 7: 292. https://goo.gl/xpuZCG
(a)
(b)
Figure 11: Wide-Angle X-Ray Diffraction (WAXD) analysis of malignant human
cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
(a)
(b)
Figure 12: Grazing-Incidence X-0Ray Diffraction (GIXD) analysis of malignant
human cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
(a)
(b)
Figure 13: Energy-Dispersive X-Ray Diffraction (EDXRD) analysis of malignant
human cancer cells and tissues (a) before and (b) after irradiating of synchrotron
radiation in transformation process to benign human cancer cells and tissues
with the passing of time [1-141].
5. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 005
19. Alireza H. Spectroscopy and quantum mechanics of the Helium Dimer (He2+
),
Neon Dimer (Ne2+
), Argon Dimer (Ar2+
), Krypton Dimer (Kr2+
), Xenon Dimer
(Xe2+
), Radon Dimer(Rn2+
) and Ununoctium Dimer (Uuo2+
) molecular cations.
Chem Sci J. 2016; 7: 112. https://goo.gl/nQkfhZ
20. Alireza H. Human toxicity photodynamic therapy studies on DNA/RNA
complexes as a promising new sensitizer for the treatment of malignant
tumors using bio-spectroscopic techniques. J Drug Metab Toxicol. 2016; 7:
129. https://goo.gl/PJHv1K
21. Alireza H. Novel and stable modifications of intelligent Cadmium Oxide (CdO)
nanoparticles as anti- cancer drug in formation of nucleic acids complexes
for human cancer cells’ treatment. Biochem Pharmacol (Los Angel). 2016; 5:
207. https://goo.gl/D9Uy1j
22. Alireza H. A combined computational and QM/MM molecular dynamics study
on Boron Nitride Nanotubes (BNNTs), Amorphous Boron Nitride Nanotubes
(a-BNNTs) and Hexagonal Boron Nitride Nanotubes (h-BNNTs) as hydrogen
storage. Struct Chem Crystallogr Commun. 2016; 2: 1. https://goo.gl/ceAQdd
23. Alireza H. Pharmaceutical and analytical chemistry study of Cadmium Oxide
(CdO) nanoparticles synthesis methods and properties as anti-cancer drug
and its effect on human cancer cells. Pharm Anal Chem Open Access. 2016;
2: 113. https://goo.gl/ZxZ6Cj
24. Alireza H. A chemotherapeutic and biospectroscopic investigation of the
interaction of double-standard DNA/RNA-binding molecules with Cadmium
Oxide (CdO) and Rhodium (III) Oxide (Rh2
O3
) nanoparticles as anti-cancer
drugs for cancer cells’ treatment. Chemo Open Access. 2016; 5: 129. https://
goo.gl/PxQisL
25. Alireza H. Pharmacokinetics and experimental therapeutic study of DNA
and other biomolecules using lasers: advantages and applications. J
Pharmacokinet Exp Ther. 2016; 1: 5. https://goo.gl/Amb9DU
26. Alireza H. Determination of ratio and stability constant of DNA/RNA in
human cancer cells and Cadmium Oxide (CdO) nanoparticles complexes
using analytical electrochemical and spectroscopic techniques. Insights Anal
Electrochem. 2016; 2: 1. https://goo.gl/N7C7XG
27. Alireza H. Discriminate between antibacterial and non-antibacterial drugs
artificial neutral networks of a Multilayer Perceptron (MLP) type using a set
of topological descriptors. J Heavy Met Toxicity Dis. 2016; 1: 2. https://goo.
gl/6nBxQu
28. Alireza H. Combined theoretical and computational study of the belousov-
zhabotinsky chaotic reaction and curtius rearrangement for synthesis of
mechlorethamine, cisplatin, streptozotocin, cyclophosphamide, melphalan,
busulphan and BCNU as anti-cancer drugs. Insights Med Phys. 2016; 1: 2.
https://goo.gl/EMGwKM
29. Alireza H. A translational biomedical approach to structural arrangement of
amino acids’ complexes: a combined theoretical and computational study.
Transl Biomed. 2016; 7: 2. https://goo.gl/JYztY5
30. Alireza H. Ab initio and Density Functional Theory (DFT) studies of dynamic
NMR shielding tensors and vibrational frequencies of DNA/RNA and
Cadmium Oxide (CdO) nanoparticles complexes in human cancer cells. J
Nanomedine Biotherapeutic Discov. 2016; 6: 144. https://goo.gl/uue3XW
31. Alireza H. Molecular dynamics and monte-carlo simulations for replacement
sugars in insulin resistance, obesity, LDL cholesterol, triglycerides, metabolic
syndrome, type 2 diabetes and cardiovascular disease: a glycobiological
study. J Glycobiol. 2016; 5: 111. https://goo.gl/8mb6nA
32. Alireza H. Synthesis and study of 5-[(Phenylsulfonyl) Amino]-1,3,4-
Thiadiazole-2-sulfonamide as potential anti-pertussis drug using
chromatography and spectroscopy techniques. Transl Med (Sunnyvale).
2016; 6: 138. https://goo.gl/RA8WSA
33. Alireza H. Nitrogen, oxygen, phosphorus and sulphur heterocyclic anti-cancer
nano drugs separation in the supercritical fluid of Ozone (O3
) using Soave-
Redlich-Kwong (SRK) and Pang-Robinson (PR) equations. Electronic J Biol.
2016; 12: 4. https://goo.gl/kSQwqg
34. Alireza H. An analytical and computational infrared spectroscopic review of
vibrational modes in nucleic acids. Austin J Anal Pharm Chem. 2016; 3: 1058.
https://goo.gl/shJgDL
35. Alireza H, Brown C. Phase, composition and morphology study and analysis
of Os-Pd/HfC nanocomposites. Nano Res Appl. 2016; 2: 1. https://goo.
gl/5WcY9n
36. Alireza H, Brown C. Vibrational spectroscopic study of intensities and shifts of
symmetric vibration modes of ozone diluted by cumene. International Journal
of Advanced Chemistry. 2016; 4: 5-9. https://goo.gl/x2JYtp
37. Alireza H. Study of the role of anti-cancer molecules with different sizes for
decreasing corresponding bulk tumor multiple organs or tissues. Arch Can
Res. 2016; 4: 2. https://goo.gl/DZmvzY
38. Alireza H. Genomics and proteomics studies of zolpidem, necopidem,
alpidem, saripidem, miroprofen, zolimidine, olprinone and abafungin as anti-
tumor, peptide antibiotics, antiviral and Central Nervous System (CNS) drugs.
J Data Mining Genomics & Proteomics. 2016; 7: 125. https://goo.gl/vjoRjb
39. Alireza H. Pharmacogenomics and pharmacoproteomics studies of
Phosphodiesterase-5 (PDE5) inhibitors and paclitaxel albumin-stabilized
nanoparticles as sandwiched anti-cancer nano drugs between two DNA/RNA
molecules of human cancer cells. J Pharmacogenomics Pharmacoproteomics.
2016; 7: 153. https://goo.gl/Xd3Qzn
40. Alireza H. Biotranslational medical and biospectroscopic studies of Cadmium
Oxide (CdO) nanoparticles-DNA/RNA straight and cycle chain complexes
as potent anti-viral, anti-tumor and anti- microbial drugs: a clinical approach.
Transl Biomed. 2016; 7: 2. https://goo.gl/fQgqvf
41. Alireza H. A comparative study on simultaneous determination and separation
of adsorbed Cadmium Oxide (CdO) nanoparticles on DNA/RNA of human
cancer cells using biospectroscopic techniques and Dielectrophoresis (DEP)
method. Arch Can Res. 2016; 4: 2. https://goo.gl/3j2fdy
42. Alireza H. Cheminformatics and system chemistry of cisplatin, carboplatin,
nedaplatin, oxaliplatin, heptaplatin and lobaplatin as anti-cancer nano drugs:
a combined computational and experimental study. J Inform Data Min. 2016;
1: 3. https://goo.gl/3j8zBk
43. Alireza H. Linear and non-linear Quantitative Structure-Anti-Cancer-Activity
Relationship (QSACAR) study of hydrous ruthenium (IV) Oxide (RuO2
)
Nanoparticles as Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
and anti-cancer nano drugs. J Integr Oncol. 2016; 5: 110. https://goo.gl/
TqV4Jz
44. Alireza H. Synthesis, characterization and biospectroscopic studies of
Cadmium Oxide (CdO) nanoparticles-nucleic acids complexes absence of
soluble polymer as a protective agent using nucleic acids condensation and
solution reduction method. J Nanosci Curr Res. 2016; 1: 101. https://goo.gl/
aWKoyn
45. Alireza H. Coplanarity and collinearity of 4’-Dinonyl-2,2’-Bithiazole in one
domain of bleomycin and pingyangmycin to be responsible for binding of
Cadmium Oxide (CdO) nanoparticles to DNA/RNA bidentate ligands as anti-
tumor nano drug. Int J Drug Dev & Res. 2016; 8: 7-8. https://goo.gl/PWzadm
46. Alireza H. A pharmacovigilance study on linear and non-linear Quantitative
Structure (Chromatographic) Retention Relationships (QSRR) models for
the prediction of retention time of anti-cancer nano drugs under synchrotron
radiations. J Pharmacovigil. 2016; 4: 161. https://goo.gl/H2dCBX
47. Alireza H. Nanotechnology in preparation of semipermeable polymers. J Adv
Chem Eng. 2016; 6: 157. https://goo.gl/7erQij
48. Alireza H. A gastrointestinal study on linear and non-linear Quantitative
Structure (Chromatographic) Retention Relationships (QSRR) models for
analysis 5-Aminosalicylates nano particles as digestive system nano drugs
under synchrotron radiations. J Gastrointest Dig Syst. 2016; 6: 119. https://
goo.gl/U7jw8G
49. Alireza H. DNA/RNA fragmentation and cytolysis in human cancer cells
treated with diphthamide nano particles derivatives. Biomedical Data Mining.
2016; 5: 102. https://goo.gl/icwVz7
50. Alireza H. A successful strategy for the prediction of solubility in the
construction of Quantitative Structure-Activity Relationship (QSAR) and
Quantitative Structure-Property Relationship (QSPR) under synchrotron
radiations using Genetic Function Approximation (GFA) algorithm. J Mol Biol
Biotechnol. 2016; 1: 1. https://goo.gl/RmwV7e
51. Alireza Heidari. Computational study on molecular structures of C20
, C60
,
C240
, C540
, C960
, C2160
and C3840
fullerene nano molecules under synchrotron
radiations using fuzzy logic. J Material Sci Eng. 2016; 5: 282. https://goo.gl/
h8jsBE
52. Alireza Heidari. Graph theoretical analysis of zigzag polyhexamethylene
biguanide, polyhexamethylene adipamide, polyhexamethylene biguanide
gauze and Polyhexamethylene Biguanide Hydrochloride (PHMB) Boron
6. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 006
Nitride Nanotubes (BNNTs), Amorphous Boron Nitride Nanotubes (a-BNNTs)
and Hexagonal Boron Nitride Nanotubes (h-BNNTs). J Appl Computat Math.
2016; 5: 143. https://goo.gl/oGzF1j
53. Alireza Heidari. The impact of high resolution imaging on diagnosis. Int J Clin
Med Imaging. 2016; 3: 101. https://goo.gl/WhjJsR
54. Alireza Heidari. A comparative study of conformational behavior of Isotretinoin
(13-Cis Retinoic Acid) and Tretinoin (All-Trans Retinoic Acid (ATRA)) nano
particles as anti-cancer nano drugs under synchrotron radiations using
Hartree-Fock (HF) and Density Functional Theory (DFT) methods. Insights in
Biomed. 2016; 1: 2. https://goo.gl/SJ8nYX
55. Alireza Heidari. Advances in logic, operations and computational mathematics.
J Appl Computat Math. 2016; 5: 5. https://goo.gl/Bdjb7b
56. Alireza Heidari. Mathematical equations in predicting physical behavior. J
Appl Computat Math. 2016; 5: 5. https://goo.gl/c8Hxji
57. Alireza Heidari. Chemotherapy a Last Resort for Cancer Treatment. Chemo
Open Access. 2016; 5: 130. https://goo.gl/KohqZ8
58. Alireza Heidari. Separation and pre-concentration of metal cations-dna/rna
chelates using molecular beam mass spectrometry with tunable Vacuum
Ultraviolet (VUV) synchrotron radiation and various analytical methods. Mass
Spectrom Purif Tech. 2016; 2: 101.
59. Alireza Heidari. Yoctosecond Quantitative Structure-Activity Relationship
(QSAR) and Quantitative Structure-Property Relationship (QSPR) under
synchrotron radiations studies for prediction of solubility of anti- cancer nano
drugs in aqueous solutions using Genetic Function Approximation (GFA)
algorithm. Insight Pharm Res. 2016; 1: 6. https://goo.gl/ZiC5Af
60. Alireza Heidari. Cancer risk prediction and assessment in human cells under
synchrotron radiations using Quantitative Structure Activity Relationship
(QSAR) and Quantitative Structure Properties Relationship (QSPR) studies.
Int J Clin Med Imaging. 2016; 3: 516. https://goo.gl/Gxa9Ed
61. Alireza Heidari. A novel approach to biology. Electronic J Biol. 2016; 12: 3.
https://goo.gl/MUALs1
62. Alireza Heidari. Innovative biomedical equipment’s for diagnosis and
treatment. J Bioengineer & Biomedical Sci. 2016; 6: 2.
63. Alireza Heidari. Integrating precision cancer medicine into healthcare,
medicare reimbursement changes and the practice of oncology: trends in
oncology medicine and practices. J Oncol Med & Pract. 2016; 1: 2. https://
goo.gl/Hhw6H9
64. Alireza Heidari. Promoting convergence in biomedical and biomaterials
sciences and silk proteins for biomedical and biomaterials applications: an
introduction to materials in medicine and bioengineering perspectives. J
Bioengineer & Biomedical Sci. 2016; 6: 3. https://goo.gl/e6SCZn
65. Alireza Heidari. X-ray fluorescence and x-ray diffraction analysis on discrete
element modeling of nano powder metallurgy processes in optimal container
design. J Powder Metall Min. 2017; 6: 1. https://goo.gl/gq9zaq
66. Alireza Heidari. Biomolecular spectroscopy and dynamics of nano-sized
molecules and clusters as cross- linking-induced anti-cancer and immune-
oncology nano drugs delivery in DNA/RNA of human cancer cells’ membranes
under synchrotron radiations: a payload-based perspective. Arch Chem Res.
2017; 1: 2. https://goo.gl/SiSEY4
67. Alireza Heidari. Deficiencies in repair of double-standard DNA/RNA-binding
molecules identified in many types of solid and liquid tumors oncology
in human body for advancing cancer immunotherapy using computer
simulations and data analysis. J Appl Bioinforma Comput Biol. 2017; 6: 1.
https://goo.gl/N345kj
68. Alireza Heidari. Electronic coupling among the five nanomolecules shuts
down quantum tunneling in the presence and absence of an applied magnetic
field for indication of the dimer or other provide different influences on the
magnetic behavior of single molecular magnets (smms) as qubits for quantum
computing. Glob J Res Rev. 2017; 4: 2. https://goo.gl/UNqEYL
69. Alireza Heidari. Polymorphism in nano-sized graphene ligand-induced
transformation of Au38
-xAgx
/xCux
(SPh-tBu)24
to Au36
-xAgx
/xCux
(SPh-tBu)24
(x = 1-12) Nanomolecules for Synthesis of Au144
- xAgx
/xCux
[(SR)60
, (SC4
)60
,
(SC6
)60
, (SC12
)60
, (PET)60
, (p- MBA)60
, (F)60
, (Cl)60
, (Br)60
, (I)60
, (At)60
, (Uus)60
and (SC6
H13
)60
] nano clusters as anti-cancer nano drugs. J Nanomater Mol
Nanotechnol. 2017; 6: 3. https://goo.gl/v7n1Xz
70. Alireza Heidari. Biomedical resource oncology and data mining to enable
resource discovery in medical, medicinal, clinical, pharmaceutical, chemical
and translational research and their applications in cancer research. Int J
Biomed Data Min. 2017; 6: 2. https://goo.gl/Je2cX4
71. Alireza Heidari. Study of synthesis, pharmacokinetics, pharmacodynamics,
dosing, stability, safety and efficacy of olympiadane nanomolecules as agent
for cancer enzymotherapy, immunotherapy, chemotherapy, radiotherapy,
hormone therapy and targeted therapy under synchrotorn radiation. J Dev
Drugs. 2017; 6: 154. https://goo.gl/sQy5wg
72. Alireza Heidari. A novel approach to future horizon of top seven biomedical
research topics to watch in 2017: alzheimer’s, ebola, hypersomnia, Human
Immunodeficiency Virus (HIV), Tuberculosis (TB), microbiome/antibiotic
resistance and endovascular stroke. J Bioengineer & Biomedical Sci. 2017;
7: 127. https://goo.gl/5WKVqb
73. Alireza Heidari. Opinion on Computational Fluid Dynamics (CFD) technique.
Fluid Mech Open Acc. 2017; 4: 157. https://goo.gl/NcNh8e
74. Alireza Heidari. Concurrent diagnosis of oncology influence outcomes in
emergency general surgery for colorectal cancer and Multiple Sclerosis (MS)
treatment using Magnetic Resonance Imaging (MRI) and Au329
(SR)84
, Au329-
x
Agx
(SR)84
, Au144
(SR)60
, Au68
(SR)36
, Au30
(SR)18
, Au102
(SPh)44
, Au38
(SPh)24
,
Au38
(SC2
H4
Ph)24
, Au21
S(SAdm)15
, Au36
(pMBA)24
and Au25
(pMBA)18
nano
clusters. J Surgery Emerg Med. 2017; 1: 21. https://goo.gl/kY8pb4
75. Alireza Heidari. Developmental cell biology in adult stem cells death and
autophagy to trigger a preventive allergic reaction to common airborne
allergens under synchrotron radiation using nanotechnology for therapeutic
goals in particular allergy shots (Immunotherapy). Cell Biol (Henderson, NV).
2017; 6: 1. https://goo.gl/TpsocC
76. Alireza Heidari. Changing metal powder characteristics for elimination of
the heavy metals toxicity and diseases in disruption of Extracellular Matrix
(ECM) proteins adjustment in cancer metastases induced by osteosarcoma,
chondrosarcoma, carcinoid, carcinoma, ewing’s sarcoma, fibrosarcoma and
secondary hematopoietic solid or soft tissue tumors. J Powder Metall Min.
2017; 6: 170. https://goo.gl/MA27gP
77. Alireza Heidari. Nanomedicine-based combination anti-cancer therapy
between nucleic acids and anti- cancer nano drugs in covalent nano drugs
delivery systems for selective imaging and treatment of human brain tumors
using hyaluronic acid, alguronic acid and sodium hyaluronate as anti-cancer
Nano drugs and nucleic acids delivery under synchrotron radiation. Am J
Drug Deliv. 2017; 5: 2. https://goo.gl/g1ydHg
78. Alireza Heidari. Clinical trials of dendritic cell therapies for cancer exposing
vulnerabilities in human cancer cells’ metabolism and metabolomics: new
discoveries, unique features inform new therapeutic opportunities, biotech’s
bumpy road to the market and elucidating the biochemical programs that
support cancer initiation and progression. J Biol Med Science. 2017; 1: 103.
https://goo.gl/jzgvvM
79. Alireza Heidari. The design graphene-based nanosheets as a new
nanomaterial in anti-cancer therapy and delivery of chemotherapeutics and
biological nano drugs for liposomal anti-cancer nano drugs and gene delivery.
Br Biomed Bull. 2017; 5: 305. https://goo.gl/EKp1jG
80. Alireza Heidari. Integrative approach to biological networks for emerging
roles of proteomics, genomics and transcriptomics in the discovery and
validation of human colorectal cancer biomarkers from DNA/RNA sequencing
data under synchrotron radiation. Transcriptomics. 2017; 5: 117. https://goo.
gl/WZVmEc
81. Alireza Heidari. Elimination of the heavy metals toxicity and diseases in
disruption of Extracellular Matrix (ECM) proteins and cell adhesion intelligent
nanomolecules adjustment in cancer metastases using metalloenzymes and
under synchrotron radiation. Lett Health Biol Sci. 2017; 2: 78-81. https://goo.
gl/JJR84p
82. Alireza Heidari. Treatment of breast cancer brain metastases through
a targeted nanomolecule drug delivery system based on dopamine
functionalized Multi-Wall Carbon Nanotubes (MWCNTs) coated with nano
Graphene Oxide (GO) and Protonated Polyaniline (PANI) in situ during the
polymerization of aniline autogenic nanoparticles for the delivery of anti-
cancer Nano drugs under synchrotron radiation. Br J Res. 2017; 4: 16. https://
goo.gl/w7pvpy
83. Alireza Heidari. Sedative, analgesic and ultrasound-mediated gastrointestinal
nano drugs delivery for gastrointestinal endoscopic procedure, nano drug-
induced gastrointestinal disorders and nano drug treatment of gastric acidity.
Res Rep Gastroenterol. 2017; 1: 1.
7. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 007
84. Alireza Heidari. Synthesis, pharmacokinetics, pharmacodynamics dosing,
stability, safety and efficacy of orphan nano drugs to treat high cholesterol and
related conditions and to prevent cardiovascular disease under synchrotron
radiation. J Pharm Sci Emerg Drugs. 2017; 5: 1. https://goo.gl/vY3ynL
85. Alireza Heidari. Non-linear compact proton synchrotrons to improve human
cancer cells and tissues treatments and diagnostics through particle therapy
accelerators with monochromatic microbeams. Cell Immunol Serum Biol.
2017; 3: 115-119. https://goo.gl/beuzBZ
86. Alireza Heidari. Design of targeted metal chelation therapeutics nanocapsules
as colloidal carriers and Blood-Brain Barrier (BBB) translocation to targeted
deliver anti-cancer nano drugs into the human brain to treat alzheimer’s
disease under synchrotron radiation. J Nanotechnol Material Sci. 2017; 4:
62-66. https://goo.gl/65zcgE
87. Ricardo Gobato, Alireza Heidari. Calculations using quantum chemistry for
inorganic molecule simulation BeLi2
SeSi. American Journal of Quantum
Chemistry and Molecular Spectroscopy. 2017; 2: 76-85. https://goo.gl/
c2h2sQ
88. Alireza Heidari. Different high-resolution simulations of medical, medicinal,
clinical, pharmaceutical and therapeutics oncology of human lung cancer
translational anti-cancer nano drugs delivery treatment process under
synchrotron and x-ray radiations. J Med Oncol. 2017; 1: 12-18. https://goo.gl/
mxJ5Zv
89. Alireza Heidari. A modern ethnomedicinal technique for transformation,
prevention and treatment of human malignant gliomas tumors into human
benign gliomas tumors under synchrotron radiation. Am J Ethnomed. 2017;
4: 10. https://goo.gl/5iwpdX
90. Alireza Heidari. An investigation of the role of DNA as molecular computers:
a computational study on the hamiltonian path problem. International Journal
of Scientific & Engineering Research. 2014; 5: 1884-1889. https://goo.gl/
LqfW9X
91. Alireza Heidari. Active targeted nanoparticles for anti-cancer nano drugs
delivery across the blood- brain barrier for human brain cancer treatment,
Multiple Sclerosis (MS) and alzheimer’s diseases using chemical
modifications of anti-cancer nano drugs or drug-nanoparticles through Zika
Virus (ZIKV) nanocarriers under synchrotron radiation. J Med Chem Toxicol.
2017; 2: 90-94. https://goo.gl/UnHbns
92. Alireza Heidari. Investigation of medical, medicinal, clinical and
pharmaceutical applications of estradiol, mestranol (Norlutin), Norethindrone
(NET), Norethisterone Acetate (NETA), Norethisterone Enanthate (NETE)
and testosterone nanoparticles as biological imaging, cell labeling, anti-
microbial agents and anti-cancer nano drugs in nanomedicines based drug
delivery systems for anti-cancer targeting and treatment. Parana Journal of
Science and Education. 2017; 3: 10-19. https://goo.gl/MBBkLn
93. Alireza Heidari. A comparative computational and experimental study on
different vibrational biospectroscopy methods, techniques and applications
for human cancer cells in tumor tissues simulation, modeling, research,
diagnosis and treatment. Open J Anal Bioanal Chem. 2017; 1: 14-20. https://
goo.gl/LPCqZC
94. Alireza Heidari. Combination of DNA/RNA ligands and Linear/Non-Linear
visible-synchrotron radiation- driven n-doped ordered mesoporous Cadmium
Oxide (CdO) nanoparticles photocatalysts channels resulted in an interesting
synergistic effect enhancing catalytic anti-cancer activity. Enz Eng. 2017; 6:
1. https://goo.gl/2wgZFN
95. Alireza Heidari. Modern approaches in designing ferritin, ferritin light chain,
transferrin, beta-2 transferrin and bacterioferritin-based anti-cancer nano
drugs encapsulating nanosphere as DNA-binding proteins from Starved Cells
(DPS). Mod Appro Drug Des. 2017; 1: 1-5. https://goo.gl/TPik1M
96. Alireza Heidari. Potency of human interferon β-1a and human interferon β-1b
in enzymotherapy, immunotherapy, chemotherapy, radiotherapy, hormone
therapy and targeted therapy of encephalomyelitis disseminate/Multiple
Sclerosis (MS) and hepatitis A, B, C, D, E, F and G virus enter and targets
liver cells. J Proteomics Enzymol. 2017; 6: 1. https://goo.gl/bJ9oCq
97. Alireza Heidari. Transport therapeutic active targeting of human brain tumors
enable anti-cancer nanodrugs delivery across the Blood-Brain Barrier
(BBB) to treat brain diseases using nanoparticles and nanocarriers under
synchrotron radiation. J Pharm Pharmaceutics. 2017; 4: 151-155. https://goo.
gl/DTw2W8
98. Alireza Heidari. Christopher brown, combinatorial therapeutic approaches
to DNA/RNA and Benzylpenicillin (Penicillin G), Fluoxetine Hydrochloride
(ProzacandSarafem),Propofol(Diprivan),AcetylsalicylicAcid (ASA)(Aspirin),
Naproxen Sodium (Aleve and Naprosyn) and Dextromethamphetamine
nanocapsules with surface conjugated DNA/RNA to targeted nano drugs for
enhanced anti-cancer efficacy and targeted cancer therapy using nano drugs
delivery systems. Ann Adv Chem. 2017; 1: 61-69. https://goo.gl/RfqXj1
99. Alireza Heidari. Vibrational spectroscopy of nucleic acids. Wahid Ali Khan
(Editor). Basic Biochemistry. Austin Publishing Group (APG)/Austin
Publications LLC. ISBN: 978-0-9971499-2-0. Jersey City, New Jersey; USA;
2016. 1-18.
100. Alireza Heidari. High-resolution simulations of human brain cancer
translational nano drugs delivery treatment process under synchrotron
radiation. J Transl Res. 2017; 1: 1-3. https://goo.gl/nxxDrE
101. Alireza Heidari. Investigation of anti-cancer nano drugs’ effects’ trend
on human pancreas cancer cells and tissues prevention, diagnosis and
treatment process under synchrotron and x-ray radiations with the passage
of time using mathematica. Current Trends Anal Bioanal Chem. 2017; 1:
36-41. https://goo.gl/dkdv73
102. Alireza Heidari. Pros and cons controversy on molecular imaging and
dynamics of double-standard DNA/RNA of human preserving stem
cells-binding nano molecules with Androgens/Anabolic Steroids (AAS)
or testosterone derivatives through tracking of helium-4 nucleus (Alpha
Particle) using synchrotron radiation. Arch Biotechnol Biomed. 2017; 1:
67-100. https://goo.gl/TBXUjZ
103. Alireza Heidari. Visualizing metabolic changes in probing human cancer
cells and tissues metabolism using vivo 1
H or Proton NMR, 13
C NMR,
15
N NMR and 31
P NMR spectroscopy and self-organizing maps under
synchrotron radiation. SOJ Mater Sci Eng. 2017; 5: 1-6. https://goo.gl/
JGKBEM
104. Alireza Heidari. Cavity Ring-Down Spectroscopy (CRDS), circular
dichroism spectroscopy, cold vapour atomic fluorescence spectroscopy
and correlation spectroscopy comparative study on malignant and benign
human cancer cells and tissues with the passage of time under synchrotron
radiation. Enliven: Challenges Cancer Detect Ther. 2017; 4: 1. https://goo.
gl/bwUFJB
105. Alireza Heidari. Laser spectroscopy, laser-induced breakdown
spectroscopy and laser-induced plasma spectroscopy comparative study
on malignant and benign human cancer cells and tissues with the passage
of time under synchrotron radiation. Int J Hepatol Gastroenterol. 2017; 3:
79-84. https://goo.gl/iJNvEP
106. Alireza Heidari. Time-resolved spectroscopy and time-stretch spectroscopy
comparative study on malignant and benign human cancer cells and
tissues with the passage of time under synchrotron radiation. Enliven:
Pharmacovigilance and Drug Safety. 2017; 4: 1. https://goo.gl/2DQKaF
107. Alireza Heidari. Overview of the role of vitamins in reducing negative
effect of Decapeptyl (Triptorelin Acetate or Pamoate Salts) on prostate
cancer cells and tissues in prostate cancer treatment process through
transformation of malignant prostate tumors into benign prostate tumors
under synchrotron radiation. Open J Anal Bioanal Chem. 2017; 1: 21-26.
108. Alireza Heidari. Electron Phenomenological Spectroscopy, Electron
Paramagnetic Resonance (EPR) Spectroscopy and Electron Spin
Resonance (ESR) spectroscopy comparative study on malignant and
benign human cancer cells and tissues with the passage of time under
synchrotron radiation. Austin J Anal Pharm Chem. 2017; 4: 1091.
109. Alireza Heidari. Therapeutic nanomedicine different high-resolution
experimental images and computational simulations for human brain
cancer cells and tissues using nanocarriers deliver DNA/RNA to brain
tumors under synchrotron radiation with the passage of time using
mathematica and MATLAB. Madridge J Nano Tech Sci. 2017; 2: 77-83.
https://goo.gl/dBcK9n
110. Alireza Heidari. A consensus and prospective study on restoring Cadmium
Oxide (CdO) nanoparticles sensitivity in recurrent ovarian cancer by
extending the Cadmium Oxide (CdO) nanoparticles-free interval using
synchrotron radiation therapy as antibody-drug conjugate for the treatment
of limited-stage small cell diverse epithelial cancers. Cancer Clin Res Rep.
2017; 1: 1. https://goo.gl/Q9G5hw
111. Alireza Heidari. A novel and modern experimental imaging and
spectroscopy comparative study on malignant and benign human cancer
8. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 008
cells and tissues with the passage of time under white synchrotron
radiation. Cancer Sci Res Open Access. 2017; 4: 1-8. https://goo.gl/
XeK3AZ
112. Alireza Heidari. Different high-resolution simulations of medical, medicinal,
clinical, pharmaceutical and therapeutics oncology of human breast cancer
translational nano drugs delivery treatment process under synchrotron
and x-ray radiations. J Oral Cancer Res. 2017; 1: 12-17. https://goo.gl/
z2RBmW
113. Alireza Heidari. Vibrational Decihertz (dHz), Centihertz (cHz), Millihertz
(mHz), Microhertz (μHz), Nanohertz (nHz), Picohertz (pHz), Femtohertz
(fHz), Attohertz (aHz), Zeptohertz (zHz) and Yoctohertz (yHz) imaging and
spectroscopy comparative study on malignant and benign human cancer
cells and tissues under synchrotron radiation. International Journal of
Biomedicine. 2017; 7: 335-340. https://goo.gl/hsRKjw
114. Alireza Heidari. Force spectroscopy and fluorescence spectroscopy
comparative study on malignant and benign human cancer cells and
tissues with the passage of time under synchrotron radiation. EC Cancer.
2017; 2: 239-246. https://goo.gl/iJXDgM
115. Alireza Heidari. Photoacoustic spectroscopy, photoemission spectroscopy
and photothermal spectroscopy comparative study on malignant and
benign human cancer cells and tissues with the passage of time under
synchrotron radiation. BAOJ Cancer Res Ther. 2017; 3: 45-52. https://goo.
gl/BgZz88
116. Alireza Heidari. J-Spectroscopy, Exchange Spectroscopy (EXSY),
Nuclear Overhauser Effect Spectroscopy (NOESY) and Total Correlation
Spectroscopy (TOCSY) comparative study on malignant and benign
human cancer cells and tissues under synchrotron radiation. EMS Eng Sci
J. 2017; 1: 6-13.
117. Alireza Heidari. Neutron spin echo spectroscopy and spin noise
spectroscopy comparative study on malignant and benign human cancer
cells and tissues with the passage of time under synchrotron radiation. Int
J Biopharm Sci. 2017; 1: 103-107. https://goo.gl/fWXV51
118. Alireza Heidari. Vibrational Decahertz (daHz), Hectohertz (hHz), Kilohertz
(kHz), Megahertz (MHz), Gigahertz (GHz), Terahertz (THz), Petahertz
(PHz), Exahertz (EHz), Zettahertz (ZHz) and Yottahertz (YHz) imaging and
spectroscopy comparative study on malignant and benign human cancer
cells and tissues under synchrotron radiation. Madridge J Anal Sci Instrum.
2017; 2: 41-46. https://goo.gl/gwPsJJ
119. Alireza Heidari. Two-dimensional infrared correlation spectroscopy, linear
two-dimensional infrared spectroscopy and non-linear two-dimensional
infrared spectroscopy comparative study on malignant and benign human
cancer cells and tissues under synchrotron radiation with the passage of
time. J Mater Sci Nanotechnol. 2018; 6: 101. https://goo.gl/oJ8RRE
120. Alireza Heidari. Fourier Transform Infrared (FTIR) Spectroscopy, Near-
Infrared Spectroscopy (NIRS) and Mid-Infrared Spectroscopy (MIRS)
comparative study on malignant and benign human cancer cells and
tissues under synchrotron radiation with the passage of time. Int J
Nanotechnol Nanomed. 2018; 3: 1-6. https://goo.gl/TnHYTX
121. Alireza Heidari. Infrared photo dissociation spectroscopy and infrared
correlation table spectroscopy comparative study on malignant and benign
human cancer cells and tissues under synchrotron radiation with the
passage of time. Austin Pharmacol Pharm. 2018; 3: 1011.
122. Alireza Heidari. Novel and transcendental prevention, diagnosis and
treatment strategies for investigation of interaction among human blood
cancer cells, tissues, tumors and metastases with synchrotron radiation
under anti-cancer nano drugs delivery efficacy using MATLAB modeling
and simulation. Madridge J Nov Drug Res. 2017; 1: 18-24. https://goo.gl/
faCgam
123. Alireza Heidari. Comparative study on malignant and benign human cancer
cells and tissues with the passage of time under synchrotron radiation.
Open Access J Trans Med Res. 2018; 2: 26-32. https://goo.gl/thby1f
124. Marcia Regina Risso Gobato, Ricardo Gobato, Alireza Heidari. Planting
of jaboticaba trees for landscape repair of degraded area. Landscape
Architecture and Regional Planning. 2018; 3: 1-9. https://goo.gl/111sXc
125. Alireza Heidari. Fluorescence spectroscopy, phosphorescence
spectroscopy and luminescence spectroscopy comparative study on
malignant and benign human cancer cells and tissues under synchrotron
radiation with the passage of time. SM J Clin Med Imaging. 2018; 4: 1018.
126. Alireza Heidari. Nuclear Inelastic Scattering Spectroscopy (NISS) and
Nuclear Inelastic Absorption Spectroscopy (NIAS) comparative study on
malignant and benign human cancer cells and tissues under synchrotron
radiation. Int J Pharm Sci. 2018; 2: 1-14.
127. Alireza Heidari. X-Ray Diffraction (XRD), Powder X-Ray Diffraction (PXRD)
and Energy-Dispersive X-Ray Diffraction (EDXRD) comparative study on
malignant and benign human cancer cells and tissues under synchrotron
radiation. J Oncol Res. 2018; 2: 1-14. https://goo.gl/uTxgfF
128. Alireza Heidari. Correlation two-dimensional Nuclear Magnetic Resonance
(NMR) (2D-NMR) (COSY) imaging and spectroscopy comparative study on
malignant and benign human cancer cells and tissues under synchrotron
radiation. EMS Can Sci. 2018; 1: 1-7. https://goo.gl/4Z9SLu
129. Alireza Heidari. Thermal spectroscopy, photothermal spectroscopy,
thermal microspectroscopy, photothermal microspectroscopy, thermal
macrospectroscopy and photothermal macrospectroscopy comparative
study on malignant and benign human cancer cells and tissues with the
passage of time under synchrotron radiation. SM J Biometrics Biostat.
2018; 3: 1024.
130. Alireza Heidari. A modern and comprehensive experimental
biospectroscopic comparative study on human common cancers’ cells,
tissues and tumors before and after synchrotron radiation therapy. Open
Acc J Oncol Med. 2018; 1: 1-10. https://goo.gl/Dbo1im
131. Alireza Heidari. Heteronuclear Correlation Experiments such as
Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC),
Heteronuclear Multiple-Quantum Correlation Spectroscopy (HMQC)
and Heteronuclear Multiple-Bond Correlation Spectroscopy (HMBC)
comparative study on malignant and benign human endocrinology and
thyroid cancer cells and tissues under synchrotron radiation. J Endocrinol
Thyroid Res. 2018; 3: 555603. https://goo.gl/6eNFM5
132. Alireza Heidari. Nuclear Resonance Vibrational Spectroscopy (NRVS),
Nuclear Inelastic Scattering Spectroscopy (NISS), Nuclear Inelastic
Absorption Spectroscopy (NIAS) and Nuclear Resonant Inelastic X-Ray
Scattering Spectroscopy (NRIXSS) comparative study on malignant and
benign human cancer cells and tissues under synchrotron radiation. Int J
Bioorg Chem Mol Biol. 2018; 6: 1-5. https://goo.gl/8yD5gf
133. Alireza Heidari. A novel and modern experimental approach to vibrational
circular dichroism spectroscopy and video spectroscopy comparative
study on malignant and benign human cancer cells and tissues with the
passage of time under white and monochromatic synchrotron radiation.
Glob J Endocrinol Metab. 2018; 1: 1-6. https://goo.gl/Ht5XqW
134. Alireza Heidari. Pros and cons controversy on heteronuclear correlation
experiments such as Heteronuclear Single-Quantum Correlation
Spectroscopy (HSQC), Heteronuclear Multiple-Quantum Correlation
Spectroscopy (HMQC) and Heteronuclear Multiple-Bond Correlation
Spectroscopy (HMBC) comparative study on malignant and benign human
cancer cells and tissues under synchrotron radiation. EMS Pharma J.
2018; 1: 2-8.
135. Alireza Heidari. A modern comparative and comprehensive experimental
biospectroscopic study on different types of infrared spectroscopy of
malignant and benign human cancer cells and tissues with the passage
of time under synchrotron radiation. J Analyt Molecul Tech. 2018; 3: 8.
https://goo.gl/h5jEnT
136. Alireza Heidari. Investigation of cancer types using synchrotron technology
for proton beam therapy: an experimental biospectroscopic comparative
study. European Modern Studies Journal. 2018; 2: 13-29. https://goo.gl/
MzejYA
137. Alireza Heidari. Saturated spectroscopy and unsaturated spectroscopy
comparative study on malignant and benign human cancer cells and
tissues with the passage of time under synchrotron radiation. Imaging J
Clin Medical Sci. 2018; 5: 1-7. https://goo.gl/xA1upu
138. Alireza Heidari. Small-Angle Neutron Scattering (SANS) and Wide-Angle
X-Ray Diffraction (WAXD) comparative study on malignant and benign
human cancer cells and tissues under synchrotron radiation. Int J Bioorg
Chem Mol Biol. 2018; 6: 1-6. https://goo.gl/SBiWd9
139. Alireza Heidari. Investigation of bladder cancer, breast cancer, colorectal
cancer, endometrial cancer, kidney cancer, leukemia, liver, lung cancer,
melanoma, non-hodgkin lymphoma, pancreatic cancer, prostate cancer,
thyroid cancer and non- melanoma skin cancer using synchrotron
9. American Journal of Nanotechnology & Nanomedicine
SCIRES Literature - Volume 1 Issue 1 - www.scireslit.com Page - 009
technology for proton beam therapy: an experimental biospectroscopic
comparative study. Ther Res Skin Dis. 2018; 1: 1-9. https://goo.gl/3UQEJE
140. Alireza Heidari. Attenuated Total Reflectance Fourier Transform
Infrared (ATR- FTIR) Spectroscopy, Micro-Attenuated Total Reflectance
Fourier Transform Infrared (Micro-ATR-FTIR) Spectroscopy and Macro-
Attenuated Total Reflectance Fourier Transform Infrared (Macro-ATR-
FTIR) spectroscopy comparative study on malignant and benign human
cancer cells and tissues under synchrotron radiation with the passage of
time. International Journal of Chemistry Papers. 2018; 2: 1-12.
141. Alireza Heidari. Mossbauer spectroscopy, mossbauer emission
spectroscopy and 57
Fe mossbauer spectroscopy comparative study on
malignant and benign human cancer cells and tissues under synchrotron
radiation. Acta Scientific Cancer Biology. 2018; 2: 17-20. https://goo.gl/
BR14bY