- Ali was chosen as caliph five days after the assassination of Uthman, though Madina was under rebel control and there were disagreements between Ali and other Sahaba over priorities.
- Ali appointed new governors in an attempt to stabilize territories but faced opposition from Mu'awya, Talha, Al-Zubayr and the army of Mecca. This led to the Battle of Jamal.
- Further conflicts emerged, including the Battle of Siffin against Mu'awya, disagreement over the arbitration process, and a battle against the Khawarij. Ali's authority was weakened as many were killed in battles.
- Mu'awya captured Egypt after the governor was killed,