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By: Emily Bateman
What Are They?
 Adult stem cells (ASC)
 are undifferentiated cells
 that are in the body after
 development.
The Two Main Properties Of ASC
 Self-renewal-the ability to go through the cycle of cell
  division many times while still keeping its
  undifferentiated state

 Multipotency (Multidifferentiative Potential)-the
  ability to make offspring of many different cell types.
Where Are They Found?
 Any where in the body
 but are mostly
 extracted from the
 blood and bone
 marrow.
Their Uses In Medicine
Degenerative and Debilitating
        Conditions Therapy:
 ALS (Amyotrophic Lateral       Kidney Failure
    Sclerosis)                   Liver Disease
   Alzheimer's Disease          Macular Degeneration
   Autism                       Muscular Dystrophy
   Cerebral Palsy               Optic Nerve Injuries
   Degenerative Disc Disease    Parkinson’s Disease
   Erectile Dysfunction         Pulmonary
   Glaucoma                      Fibrosis, Emphysema, COP
   Hearing Loss                  D
   Heart Disease                Retinitis Pigmentosa
   Huntington's Disease         Spinal Cord Injuries
                                 Stroke
Autoimmune Conditions Therapy:
 Diabetes
 Lupus
 Multiple Sclerosis
 Rheumatoid Arthritis
Musculoskeletal Injuries Therapy:
 Knee injuries
 Osteoarthritis
 Torn Ligaments
 Sports Injuries
Cosmetic and Dermatologic
             Therapy:
 Brazilian Buttock Lifts and Coetaneous Radiation
  Treatment
 Breast Augmentation
 Facelift
 Hair Loss
The Steps To A Blood (Adult Stem
 Cell) Transplant For A leukemia
              Patient
What Is A Transplant?
 In a bone marrow, or blood
 transplant for leukemia you are
 getting rid of all the unusual
 leukocytes in a patient and are
 replacing them with the new
 ones
History Of ASC Transplants
 In 1968 the first successful bone marrow transplant
  took place.
 Bone marrow is transplanted everyday to treat a
  variety of blood and bone marrow diseases such as
  blood cancers and immune disorders.
What Is Leukemia?
 Leukemia is a cancer that affects white blood cells
  (leukocytes).
 White blood cells are made by adult stem cells and are
  released into the blood stream to fight infections.
 When you have leukemia your white blood cells don’t
  grow nor function correctly.
 These cells can no longer fight infections and conflict
  with functions of other organs.
Step 1: Find A Donor
 Autologous-the donor is also infected person
 Synegenic-the donor is a twin sibling of the infected
  person
 Allogeneic-the donor is no related/not closely related
  to the infected person
 Cordbold-the donor is an umbilical cord
Step 2: Extract the Adult Stem Cells
(They’re In the Blood) From The Donor
 The donor is put on a medication for
  four to five days before the transplant
  that stimulates the production of
  adult stem cells in to the blood
  stream.
 Next, the donor must be administered
  anesthesia while the healthy blood
  cells are collected.
Step 3:If It Is An Autologous Donation
 The patient’s blood is
  put in a freezer
  (apheresis).

 After it is cold, it is
  taken in a machine that
  confines and kills the
  leukemia affected cells.
Step 3: If It Is Any Other Donation
 The Blood is frozen until needed.
Step 4: “Cleaning The Infected Patient”
  Before the patient receives the unaffected blood he/she
   goes through en enduring dose of radiation or
   chemotherapy to clear their body of any affected cells.
  Also to make sure every last affected cell is killed, doctors
   will put an additional drug in their blood stream to get the
   few cells chemo or radiation might have missed.
  This process is called purging.
  If the affected cells are not perfectly removed from the
   patient the chances are very high that they will have a
   relapse.
Step 5: Healing The Infected Patient
 After the patient is “clean”, the new blood is given to
  them.
Works Cited
 "Adult Stem Cell." Wikipedia. Wikimedia Foundation, 18 May 2012. Web. 23
  May 2012.
http://en.wikipedia.org/wiki/Adult_stem_cell

 "Frequently Asked Questions." What Are Adult Stem Cells? [Stem Cell
  Information]. Web. 23 May 2012.
http://stemcells.nih.gov/info/basics/basics4.asp

 "STEM CELLS IN USE." Stem Cells In Use. Web. 23 May 2012.
http://learn.genetics.utah.edu/content/tech/stemcells/sctoday/

 "Stem Cell Transplant Procedure." Stem Cell Transplant Procedure. Web. 23
   May 2012.
http://stem-cell-transplant.info/

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Adult stem cells

  • 2. What Are They?  Adult stem cells (ASC) are undifferentiated cells that are in the body after development.
  • 3. The Two Main Properties Of ASC  Self-renewal-the ability to go through the cycle of cell division many times while still keeping its undifferentiated state  Multipotency (Multidifferentiative Potential)-the ability to make offspring of many different cell types.
  • 4. Where Are They Found?  Any where in the body but are mostly extracted from the blood and bone marrow.
  • 5. Their Uses In Medicine
  • 6. Degenerative and Debilitating Conditions Therapy:  ALS (Amyotrophic Lateral  Kidney Failure Sclerosis)  Liver Disease  Alzheimer's Disease  Macular Degeneration  Autism  Muscular Dystrophy  Cerebral Palsy  Optic Nerve Injuries  Degenerative Disc Disease  Parkinson’s Disease  Erectile Dysfunction  Pulmonary  Glaucoma Fibrosis, Emphysema, COP  Hearing Loss D  Heart Disease  Retinitis Pigmentosa  Huntington's Disease  Spinal Cord Injuries  Stroke
  • 7. Autoimmune Conditions Therapy:  Diabetes  Lupus  Multiple Sclerosis  Rheumatoid Arthritis
  • 8. Musculoskeletal Injuries Therapy:  Knee injuries  Osteoarthritis  Torn Ligaments  Sports Injuries
  • 9. Cosmetic and Dermatologic Therapy:  Brazilian Buttock Lifts and Coetaneous Radiation Treatment  Breast Augmentation  Facelift  Hair Loss
  • 10. The Steps To A Blood (Adult Stem Cell) Transplant For A leukemia Patient
  • 11. What Is A Transplant?  In a bone marrow, or blood transplant for leukemia you are getting rid of all the unusual leukocytes in a patient and are replacing them with the new ones
  • 12. History Of ASC Transplants  In 1968 the first successful bone marrow transplant took place.  Bone marrow is transplanted everyday to treat a variety of blood and bone marrow diseases such as blood cancers and immune disorders.
  • 13. What Is Leukemia?  Leukemia is a cancer that affects white blood cells (leukocytes).  White blood cells are made by adult stem cells and are released into the blood stream to fight infections.  When you have leukemia your white blood cells don’t grow nor function correctly.  These cells can no longer fight infections and conflict with functions of other organs.
  • 14. Step 1: Find A Donor  Autologous-the donor is also infected person  Synegenic-the donor is a twin sibling of the infected person  Allogeneic-the donor is no related/not closely related to the infected person  Cordbold-the donor is an umbilical cord
  • 15. Step 2: Extract the Adult Stem Cells (They’re In the Blood) From The Donor  The donor is put on a medication for four to five days before the transplant that stimulates the production of adult stem cells in to the blood stream.  Next, the donor must be administered anesthesia while the healthy blood cells are collected.
  • 16. Step 3:If It Is An Autologous Donation  The patient’s blood is put in a freezer (apheresis).  After it is cold, it is taken in a machine that confines and kills the leukemia affected cells.
  • 17. Step 3: If It Is Any Other Donation  The Blood is frozen until needed.
  • 18. Step 4: “Cleaning The Infected Patient”  Before the patient receives the unaffected blood he/she goes through en enduring dose of radiation or chemotherapy to clear their body of any affected cells.  Also to make sure every last affected cell is killed, doctors will put an additional drug in their blood stream to get the few cells chemo or radiation might have missed.  This process is called purging.  If the affected cells are not perfectly removed from the patient the chances are very high that they will have a relapse.
  • 19. Step 5: Healing The Infected Patient  After the patient is “clean”, the new blood is given to them.
  • 20. Works Cited  "Adult Stem Cell." Wikipedia. Wikimedia Foundation, 18 May 2012. Web. 23 May 2012. http://en.wikipedia.org/wiki/Adult_stem_cell  "Frequently Asked Questions." What Are Adult Stem Cells? [Stem Cell Information]. Web. 23 May 2012. http://stemcells.nih.gov/info/basics/basics4.asp  "STEM CELLS IN USE." Stem Cells In Use. Web. 23 May 2012. http://learn.genetics.utah.edu/content/tech/stemcells/sctoday/  "Stem Cell Transplant Procedure." Stem Cell Transplant Procedure. Web. 23 May 2012. http://stem-cell-transplant.info/