Acute myocardial infarction (MI) results from occlusion of a coronary artery causing death of cardiac myocytes in the supplied region. It is usually caused by atherosclerotic plaque rupture and superimposed thrombus. Risk factors include those associated with coronary artery disease like smoking, hypertension, diabetes, and high cholesterol. MI is classified based on location of damaged tissue as STEMI or NSTEMI/unstable angina and diagnosed through symptoms, electrocardiogram (ECG) changes, and cardiac enzyme levels. Treatment involves pain management, oxygen, nitroglycerin, aspirin, fibrinolytic therapy if indicated, and long-term management of underlying risk factors.
This document defines acute myocardial infarction (AMI or heart attack) and discusses its causes, risk factors, signs and symptoms, diagnostic testing, treatment options, and long-term management. An AMI occurs when blood flow to the heart is reduced, damaging heart muscle. The main causes are blockages in the coronary arteries, often due to blood clots forming on top of plaques. Risk factors include age, family history, smoking, diabetes, high blood pressure, high cholesterol, obesity, and physical inactivity. Treatment focuses on restoring blood flow through medications, angioplasty, or bypass surgery, along with long-term lifestyle changes and medications to prevent future issues.
Myocardial infarction occurs when there is a critical imbalance between oxygen supply and demand to the heart muscle, leading to myocardial cell death. It is typically caused by rupture of an atherosclerotic plaque within the coronary artery, causing thrombosis. Diagnosis is based on symptoms, electrocardiogram changes showing ST elevation or new pathologic Q waves, and elevated cardiac biomarkers. Proper diagnosis and treatment is important to limit the extent of myocardial damage.
The document discusses acute coronary syndrome (ACS), which includes unstable angina, ST elevation myocardial infarction (STEMI), and non-ST elevation myocardial infarction (NSTEMI). ACS is characterized by new or worsening chest pain or discomfort due to reduced blood flow in the coronary arteries. The main causes are atherosclerotic plaque rupture and thrombosis formation, which can completely or partially block blood flow. Investigation and management involves ECG, cardiac biomarkers, risk stratification scores, antiplatelet and anticoagulant therapy, and often coronary angiography.
Myocardial infarction occurs when there is prolonged ischemia to the heart muscle due to reduced oxygen supply or increased oxygen demand. It is usually caused by formation of a blood clot within a coronary artery blocking blood flow. Diagnosis is made through symptoms, electrocardiogram changes, and cardiac biomarker levels. Treatment involves oxygen, aspirin, nitrates, beta blockers, fibrinolytics or percutaneous coronary intervention to restore blood flow, as well as long term medications like statins to prevent future heart attacks.
This document provides an overview of acute myocardial infarction (MI), also known as a heart attack. It discusses the definition, causes, risk factors, pathogenesis, classification, diagnosis and management of MI. The diagnosis involves taking a patient history, examining signs and symptoms, electrocardiography, serum analysis and echocardiography. Management is staged and involves pre-hospital, emergency department and post-discharge care, with a focus on reperfusing the blocked artery as quickly as possible, such as through percutaneous coronary intervention or thrombolytic therapy. The goal is to correctly identify the type of MI, treat the patient according to guidelines and manage any complications.
Acute myocardial infarction (MI) results from occlusion of a coronary artery causing death of cardiac myocytes in the supplied region. It is usually caused by atherosclerotic plaque rupture and superimposed thrombus. Risk factors include those associated with coronary artery disease like smoking, hypertension, diabetes, and high cholesterol. MI is classified based on location of damaged tissue as STEMI or NSTEMI/unstable angina and diagnosed through symptoms, electrocardiogram (ECG) changes, and cardiac enzyme levels. Treatment involves pain management, oxygen, nitroglycerin, aspirin, fibrinolytic therapy if indicated, and long-term management of underlying risk factors.
This document defines acute myocardial infarction (AMI or heart attack) and discusses its causes, risk factors, signs and symptoms, diagnostic testing, treatment options, and long-term management. An AMI occurs when blood flow to the heart is reduced, damaging heart muscle. The main causes are blockages in the coronary arteries, often due to blood clots forming on top of plaques. Risk factors include age, family history, smoking, diabetes, high blood pressure, high cholesterol, obesity, and physical inactivity. Treatment focuses on restoring blood flow through medications, angioplasty, or bypass surgery, along with long-term lifestyle changes and medications to prevent future issues.
Myocardial infarction occurs when there is a critical imbalance between oxygen supply and demand to the heart muscle, leading to myocardial cell death. It is typically caused by rupture of an atherosclerotic plaque within the coronary artery, causing thrombosis. Diagnosis is based on symptoms, electrocardiogram changes showing ST elevation or new pathologic Q waves, and elevated cardiac biomarkers. Proper diagnosis and treatment is important to limit the extent of myocardial damage.
The document discusses acute coronary syndrome (ACS), which includes unstable angina, ST elevation myocardial infarction (STEMI), and non-ST elevation myocardial infarction (NSTEMI). ACS is characterized by new or worsening chest pain or discomfort due to reduced blood flow in the coronary arteries. The main causes are atherosclerotic plaque rupture and thrombosis formation, which can completely or partially block blood flow. Investigation and management involves ECG, cardiac biomarkers, risk stratification scores, antiplatelet and anticoagulant therapy, and often coronary angiography.
Myocardial infarction occurs when there is prolonged ischemia to the heart muscle due to reduced oxygen supply or increased oxygen demand. It is usually caused by formation of a blood clot within a coronary artery blocking blood flow. Diagnosis is made through symptoms, electrocardiogram changes, and cardiac biomarker levels. Treatment involves oxygen, aspirin, nitrates, beta blockers, fibrinolytics or percutaneous coronary intervention to restore blood flow, as well as long term medications like statins to prevent future heart attacks.
This document provides an overview of acute myocardial infarction (MI), also known as a heart attack. It discusses the definition, causes, risk factors, pathogenesis, classification, diagnosis and management of MI. The diagnosis involves taking a patient history, examining signs and symptoms, electrocardiography, serum analysis and echocardiography. Management is staged and involves pre-hospital, emergency department and post-discharge care, with a focus on reperfusing the blocked artery as quickly as possible, such as through percutaneous coronary intervention or thrombolytic therapy. The goal is to correctly identify the type of MI, treat the patient according to guidelines and manage any complications.
The document discusses the current management of acute coronary syndrome in a non-interventional center. It outlines the definitions, processes of care, guidelines, and goals in diagnosing and treating ACS in the emergency department and hospital phases, including use of ECG, cardiac markers, medications, risk stratification, and addressing complications.
The document discusses a case of a 63-year-old male patient who presented with chest pain, diaphoresis, and collapse and was found to have ST elevation on electrocardiogram consistent with acute myocardial infarction. The patient's medical history included diabetes, hypertension, and previous percutaneous coronary intervention. He was taken for cardiac catheterization which showed a tight mid right coronary artery lesion and received treatment including aspirin, Plavix, statins, and ACE inhibitors upon discharge.
This document defines acute myocardial infarction and describes its predisposing factors, location, clinical presentation, management, and differential diagnosis. An AMI is caused by deficient blood supply to the heart muscle resulting in cell death. It most commonly affects the left coronary artery. Clinical features include sudden severe chest pain unrelieved by rest. Management involves oxygen, nitroglycerin, aspirin, morphine for pain relief, and transport to the hospital for further treatment.
This document provides an overview of myocardial infarction (MI), also known as a heart attack. It defines MI as diminished blood supply and cell damage in the heart muscle. Risk factors include age, gender, family history, smoking, diabetes, hypertension, hyperlipidemia, obesity, and physical inactivity. Symptoms range from chest pain to breathlessness. Diagnosis involves ECGs, cardiac enzyme levels, and cardiac imaging. Treatment depends on whether the MI is STEMI or NSTEMI and may include medications, fibrinolytic therapy, angioplasty, and lifestyle changes to modify risk factors.
M. Shareef, a 65-year-old male with diabetes and coronary artery disease, presented with chest pain, breathlessness, fever and vomiting for 6 hours. He was admitted to the ICU where an ECG showed signs of a myocardial infarction. His treatment included aspirin, clopidogrel, streptokinase, morphine and metoclopramide. As a known diabetic and heart disease patient, he requires lifestyle modifications and optimized medical management to control his risk factors and prevent further cardiac complications.
This document discusses myocardial infarction (MI), also known as a heart attack. It provides details on:
1. The criteria for diagnosing an MI, including the rise and fall of biochemical markers and characteristic ECG changes.
2. Common risk factors for MI such as high blood cholesterol, diabetes, hypertension, smoking, male gender, and family history of heart disease.
3. The pathophysiology of an MI, including how atherosclerotic plaque can rupture and cause a thrombus to form, blocking blood flow to heart muscle.
4. How an ECG can be used to detect patterns of ischemia, injury, and infarction during an MI.
The document discusses Acute Coronary Syndrome (ACS), which includes Unstable Angina/Non-ST-segment elevation myocardial infarction (UA/NSTEMI) and ST-segment elevation myocardial infarction (STEMI). UA/NSTEMI is caused by a reduction in oxygen supply or increase in demand due to plaque rupture or spasm. STEMI occurs when there is complete thrombotic occlusion of a coronary artery. Both involve chest pain but STEMI presents with ST-segment elevation on ECG. Treatment for both includes anti-ischemic, anti-thrombotic medications, and coronary revascularization if high-risk features are present.
Study Material
Myocardial infarction (MI), commonly known as a heart attack. MI is a blockage of blood flow to the heart muscle. Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium). It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart. Myocardial infarction is a common presentation of coronary artery disease. The World Health Organization estimated in 2004, that 12.2% of worldwide deaths were from ischemic heart disease.
Coronary artery disease (CAD) is a major cause of death in India. Atherosclerosis underlies most CAD cases. Unstable angina and NSTEMI are types of acute coronary syndrome (ACS) caused by a reduction in oxygen supply to the heart. The clinical presentation of ACS can include chest pain and other symptoms. Diagnosis involves ECG, cardiac biomarkers, and risk stratification. Treatment focuses on anticoagulation, antiplatelet therapy, and revascularization. Myocardial infarction (MI or heart attack) occurs when an atherosclerotic plaque ruptures completely blocking a coronary artery. This leads to necrosis of heart muscle cells. Diagnosis of MI requires specific ECG changes and elevated cardiac
A 55-year-old male smoker and alcoholic presented with chest pain and was diagnosed with a myocardial infarction based on electrocardiogram and cardiac enzyme changes. He received treatment including aspirin, nitroglycerin, morphine, and streptokinase thrombolysis and was admitted to the intensive care unit. Nursing care focused on monitoring, providing pain relief, and health teaching prior to discharge.
The document provides information on inferior wall myocardial infarction (MI), including:
1. Definitions, epidemiology, etiology, clinical features, diagnosis, treatment and complications of inferior wall MI are discussed. Worldwide over 7 million people experience STEMIs or NSTEMIs annually.
2. Diagnosis involves ECG, cardiac imaging, cardiac biomarkers like troponin and CK-MB. Reperfusion therapy within 6 hours includes PCI or thrombolysis. General treatment measures include aspirin, clopidogrel, anticoagulants, analgesics, beta-blockers, nitrates and oxygen.
3. The history of pioneers in cardiology and development of techniques like echocardi
1) STEMI/acute coronary syndrome occurs when blood supply to the heart is disrupted, damaging heart muscle. It is caused by blockages in the coronary arteries from clot formations.
2) Symptoms include chest pain that may radiate to the back, neck, or arms along with shortness of breath, nausea and weakness.
3) Risk factors include age over 45, smoking, high blood pressure, high cholesterol, diabetes and obesity.
The document discusses myocardial infarction (MI), also known as a heart attack, which occurs when blood flow to the heart is blocked due to a buildup of cholesterol, white blood cells, and fat in one of the coronary arteries. It causes symptoms like chest pain, shortness of breath, nausea, and potentially death. The document outlines the etiology, pathophysiology, clinical manifestations, diagnostic measures, management including pharmacological and surgical options, complications, prevention, and nursing care for a patient experiencing an MI.
Myocardial Infarction Pathogenesis and TreatmentPUDI CHIRANJEEVI
Myocardial infarction, or heart attack, occurs when blood flow to the heart is blocked, damaging heart muscle. There are two main types - STEMI caused by a complete blockage, and NSTEMI from a partial blockage. Risk factors include age, smoking, high cholesterol, diabetes, and family history. Diagnosis involves history, cardiac biomarkers like troponin that indicate heart damage, ECG showing elevated ST segments, and imaging tests. Treatment focuses on restoring blood flow through medications, angioplasty, or bypass surgery, along with long term preventative medications like aspirin, statins, and beta blockers.
This document provides information on myocardial infarction (MI), also known as a heart attack. It defines MI as necrosis of heart muscle tissue due to reduced blood flow and oxygen supply. Causes include atherosclerosis, blood clots, or spasms blocking coronary arteries. Risk factors include age, smoking, hypertension, high cholesterol, diabetes, obesity, physical inactivity, and stress. Symptoms include chest pain and shortness of breath. Diagnosis involves ECGs, blood tests of cardiac markers, and imaging tests. Treatment focuses on restoring blood flow, reducing pain and complications, and lifestyle changes to prevent future MIs.
This document defines myocardial infarction and provides epidemiological data. It begins by defining myocardial infarction as the irreversible necrosis of heart muscle due to prolonged ischemia resulting from a blockage in a coronary artery. It then notes that over 735,000 Americans have heart attacks each year. Risk factors include increasing age, male sex, hypertension, dyslipidemia, diabetes, smoking, obesity, physical inactivity, and excessive alcohol consumption. The pathophysiology involves rupture of an atheromatous plaque leading to thrombus formation and coronary artery occlusion, causing ischemia and eventual cell death.
GEMC - Acute Coronary Syndrome - for NursesOpen.Michigan
This document provides an overview of acute coronary syndrome (ACS) including its causes, types, risk factors, signs and symptoms, diagnosis, and treatment. It discusses the different types of ACS such as unstable angina, STEMI, and NSTEMI. For STEMI and NSTEMI it outlines the diagnostic criteria and treatments including medications, procedures, and lifestyle modifications. It also summarizes heart failure, right ventricular infarction, pulmonary edema, and cardiomyopathy.
Myocardial infarction, or heart attack, occurs when blood flow to the heart is blocked, damaging heart muscle. It is usually caused by a blood clot forming in one of the coronary arteries. A heart attack can lead to damage or death of heart muscle depending on how much of the heart is affected and for how long. Diagnosis involves assessing symptoms, electrocardiogram changes, and cardiac enzyme levels. Treatment focuses on restoring blood flow through clot-busting drugs or angioplasty, along with medications, monitoring, and lifestyle changes to prevent future heart attacks.
This document discusses the approach to evaluating and managing chest pain. It notes that chest pain is a common reason for emergency department visits and hospitalizations. A thorough history and physical exam is important to determine the likely cause, such as cardiac, pulmonary, gastrointestinal, or musculoskeletal origins. Initial testing may include an ECG, cardiac enzymes, chest x-ray, and echocardiogram. Life-threatening causes like myocardial infarction, pulmonary embolism, and aortic dissection require rapid diagnosis and treatment. Management depends on the identified condition but may include medications, procedures, or surgery.
The document discusses the current management of acute coronary syndrome in a non-interventional center. It outlines the definitions, processes of care, guidelines, and goals in diagnosing and treating ACS in the emergency department and hospital phases, including use of ECG, cardiac markers, medications, risk stratification, and addressing complications.
The document discusses a case of a 63-year-old male patient who presented with chest pain, diaphoresis, and collapse and was found to have ST elevation on electrocardiogram consistent with acute myocardial infarction. The patient's medical history included diabetes, hypertension, and previous percutaneous coronary intervention. He was taken for cardiac catheterization which showed a tight mid right coronary artery lesion and received treatment including aspirin, Plavix, statins, and ACE inhibitors upon discharge.
This document defines acute myocardial infarction and describes its predisposing factors, location, clinical presentation, management, and differential diagnosis. An AMI is caused by deficient blood supply to the heart muscle resulting in cell death. It most commonly affects the left coronary artery. Clinical features include sudden severe chest pain unrelieved by rest. Management involves oxygen, nitroglycerin, aspirin, morphine for pain relief, and transport to the hospital for further treatment.
This document provides an overview of myocardial infarction (MI), also known as a heart attack. It defines MI as diminished blood supply and cell damage in the heart muscle. Risk factors include age, gender, family history, smoking, diabetes, hypertension, hyperlipidemia, obesity, and physical inactivity. Symptoms range from chest pain to breathlessness. Diagnosis involves ECGs, cardiac enzyme levels, and cardiac imaging. Treatment depends on whether the MI is STEMI or NSTEMI and may include medications, fibrinolytic therapy, angioplasty, and lifestyle changes to modify risk factors.
M. Shareef, a 65-year-old male with diabetes and coronary artery disease, presented with chest pain, breathlessness, fever and vomiting for 6 hours. He was admitted to the ICU where an ECG showed signs of a myocardial infarction. His treatment included aspirin, clopidogrel, streptokinase, morphine and metoclopramide. As a known diabetic and heart disease patient, he requires lifestyle modifications and optimized medical management to control his risk factors and prevent further cardiac complications.
This document discusses myocardial infarction (MI), also known as a heart attack. It provides details on:
1. The criteria for diagnosing an MI, including the rise and fall of biochemical markers and characteristic ECG changes.
2. Common risk factors for MI such as high blood cholesterol, diabetes, hypertension, smoking, male gender, and family history of heart disease.
3. The pathophysiology of an MI, including how atherosclerotic plaque can rupture and cause a thrombus to form, blocking blood flow to heart muscle.
4. How an ECG can be used to detect patterns of ischemia, injury, and infarction during an MI.
The document discusses Acute Coronary Syndrome (ACS), which includes Unstable Angina/Non-ST-segment elevation myocardial infarction (UA/NSTEMI) and ST-segment elevation myocardial infarction (STEMI). UA/NSTEMI is caused by a reduction in oxygen supply or increase in demand due to plaque rupture or spasm. STEMI occurs when there is complete thrombotic occlusion of a coronary artery. Both involve chest pain but STEMI presents with ST-segment elevation on ECG. Treatment for both includes anti-ischemic, anti-thrombotic medications, and coronary revascularization if high-risk features are present.
Study Material
Myocardial infarction (MI), commonly known as a heart attack. MI is a blockage of blood flow to the heart muscle. Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium). It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart. Myocardial infarction is a common presentation of coronary artery disease. The World Health Organization estimated in 2004, that 12.2% of worldwide deaths were from ischemic heart disease.
Coronary artery disease (CAD) is a major cause of death in India. Atherosclerosis underlies most CAD cases. Unstable angina and NSTEMI are types of acute coronary syndrome (ACS) caused by a reduction in oxygen supply to the heart. The clinical presentation of ACS can include chest pain and other symptoms. Diagnosis involves ECG, cardiac biomarkers, and risk stratification. Treatment focuses on anticoagulation, antiplatelet therapy, and revascularization. Myocardial infarction (MI or heart attack) occurs when an atherosclerotic plaque ruptures completely blocking a coronary artery. This leads to necrosis of heart muscle cells. Diagnosis of MI requires specific ECG changes and elevated cardiac
A 55-year-old male smoker and alcoholic presented with chest pain and was diagnosed with a myocardial infarction based on electrocardiogram and cardiac enzyme changes. He received treatment including aspirin, nitroglycerin, morphine, and streptokinase thrombolysis and was admitted to the intensive care unit. Nursing care focused on monitoring, providing pain relief, and health teaching prior to discharge.
The document provides information on inferior wall myocardial infarction (MI), including:
1. Definitions, epidemiology, etiology, clinical features, diagnosis, treatment and complications of inferior wall MI are discussed. Worldwide over 7 million people experience STEMIs or NSTEMIs annually.
2. Diagnosis involves ECG, cardiac imaging, cardiac biomarkers like troponin and CK-MB. Reperfusion therapy within 6 hours includes PCI or thrombolysis. General treatment measures include aspirin, clopidogrel, anticoagulants, analgesics, beta-blockers, nitrates and oxygen.
3. The history of pioneers in cardiology and development of techniques like echocardi
1) STEMI/acute coronary syndrome occurs when blood supply to the heart is disrupted, damaging heart muscle. It is caused by blockages in the coronary arteries from clot formations.
2) Symptoms include chest pain that may radiate to the back, neck, or arms along with shortness of breath, nausea and weakness.
3) Risk factors include age over 45, smoking, high blood pressure, high cholesterol, diabetes and obesity.
The document discusses myocardial infarction (MI), also known as a heart attack, which occurs when blood flow to the heart is blocked due to a buildup of cholesterol, white blood cells, and fat in one of the coronary arteries. It causes symptoms like chest pain, shortness of breath, nausea, and potentially death. The document outlines the etiology, pathophysiology, clinical manifestations, diagnostic measures, management including pharmacological and surgical options, complications, prevention, and nursing care for a patient experiencing an MI.
Myocardial Infarction Pathogenesis and TreatmentPUDI CHIRANJEEVI
Myocardial infarction, or heart attack, occurs when blood flow to the heart is blocked, damaging heart muscle. There are two main types - STEMI caused by a complete blockage, and NSTEMI from a partial blockage. Risk factors include age, smoking, high cholesterol, diabetes, and family history. Diagnosis involves history, cardiac biomarkers like troponin that indicate heart damage, ECG showing elevated ST segments, and imaging tests. Treatment focuses on restoring blood flow through medications, angioplasty, or bypass surgery, along with long term preventative medications like aspirin, statins, and beta blockers.
This document provides information on myocardial infarction (MI), also known as a heart attack. It defines MI as necrosis of heart muscle tissue due to reduced blood flow and oxygen supply. Causes include atherosclerosis, blood clots, or spasms blocking coronary arteries. Risk factors include age, smoking, hypertension, high cholesterol, diabetes, obesity, physical inactivity, and stress. Symptoms include chest pain and shortness of breath. Diagnosis involves ECGs, blood tests of cardiac markers, and imaging tests. Treatment focuses on restoring blood flow, reducing pain and complications, and lifestyle changes to prevent future MIs.
This document defines myocardial infarction and provides epidemiological data. It begins by defining myocardial infarction as the irreversible necrosis of heart muscle due to prolonged ischemia resulting from a blockage in a coronary artery. It then notes that over 735,000 Americans have heart attacks each year. Risk factors include increasing age, male sex, hypertension, dyslipidemia, diabetes, smoking, obesity, physical inactivity, and excessive alcohol consumption. The pathophysiology involves rupture of an atheromatous plaque leading to thrombus formation and coronary artery occlusion, causing ischemia and eventual cell death.
GEMC - Acute Coronary Syndrome - for NursesOpen.Michigan
This document provides an overview of acute coronary syndrome (ACS) including its causes, types, risk factors, signs and symptoms, diagnosis, and treatment. It discusses the different types of ACS such as unstable angina, STEMI, and NSTEMI. For STEMI and NSTEMI it outlines the diagnostic criteria and treatments including medications, procedures, and lifestyle modifications. It also summarizes heart failure, right ventricular infarction, pulmonary edema, and cardiomyopathy.
Myocardial infarction, or heart attack, occurs when blood flow to the heart is blocked, damaging heart muscle. It is usually caused by a blood clot forming in one of the coronary arteries. A heart attack can lead to damage or death of heart muscle depending on how much of the heart is affected and for how long. Diagnosis involves assessing symptoms, electrocardiogram changes, and cardiac enzyme levels. Treatment focuses on restoring blood flow through clot-busting drugs or angioplasty, along with medications, monitoring, and lifestyle changes to prevent future heart attacks.
This document discusses the approach to evaluating and managing chest pain. It notes that chest pain is a common reason for emergency department visits and hospitalizations. A thorough history and physical exam is important to determine the likely cause, such as cardiac, pulmonary, gastrointestinal, or musculoskeletal origins. Initial testing may include an ECG, cardiac enzymes, chest x-ray, and echocardiogram. Life-threatening causes like myocardial infarction, pulmonary embolism, and aortic dissection require rapid diagnosis and treatment. Management depends on the identified condition but may include medications, procedures, or surgery.
This document discusses acute coronary syndrome (ACS) and non-ST-segment elevation acute coronary syndrome (NSTE-ACS). It defines unstable angina (UA) and non-ST elevation myocardial infarction (NSTEMI) and covers their clinical presentation, diagnostic criteria, laboratory investigation, and management. The key goals of diagnosis and treatment for NSTE-ACS patients are to recognize or exclude myocardial infarction, detect resting ischemia, and identify coronary artery obstruction. Treatment involves anti-ischemic, antithrombotic medications and consideration of coronary revascularization.
This document discusses the management of coronary artery disease and acute coronary syndrome. It begins with the anatomy of the heart and coronary blood vessels. It then defines acute coronary syndrome as unstable angina or myocardial infarction caused by plaque rupture and thrombosis. Risk factors for coronary artery disease are outlined. The diagnostic approach involves assessing symptoms, signs, electrocardiogram changes and cardiac biomarker levels. Treatment focuses on reopening the blocked vessel with medications, fibrinolytics or percutaneous coronary intervention. Chronic stable angina from established coronary artery disease is also discussed.
1. The document discusses the management of acute coronary syndrome (ACS), including risk stratification, reperfusion therapy options like fibrinolysis and percutaneous coronary intervention (PCI), and antithrombotic and antiplatelet therapies.
2. It highlights the importance of rapid reperfusion through fibrinolysis or PCI to restore blood flow and reduce mortality. PCI is generally preferred over fibrinolysis when it can be performed quickly by an experienced center.
3. Antiplatelet therapies with aspirin and clopidogrel are recommended, along with anticoagulants like unfractionated heparin or low molecular weight heparin to prevent clotting in ACS patients.
This document discusses ischaemic heart disease and angina pectoris. It defines IHD as a condition where there is inadequate blood supply and oxygen to the myocardium. Angina pectoris is defined as a clinical syndrome characterized by precordial discomfort due to myocardial ischemia, typically brought on by exertion and relieved by rest. The document covers the epidemiology, risk factors, pathophysiology, clinical manifestations, diagnosis and treatment of these conditions. It emphasizes that risk factor identification and modification are important for managing patients with known or suspected IHD.
Acute coronary syndromes (ACS) include unstable angina and myocardial infarction, which are forms of coronary heart disease caused by reduced blood flow due to plaque rupture and clot formation in the coronary arteries. The document discusses the epidemiology, risk factors, pathophysiology, clinical presentation, diagnosis, and treatment of ACS. It provides details on evaluating patients using biomarkers, ECG, risk scores, restoring blood flow through procedures like PCI or fibrinolysis, and employing antiplatelet and anticoagulant medications in the early treatment of ACS.
This document provides information on the management of angina pectoris. It discusses the different types of angina including stable angina, unstable angina, and variant angina. For stable angina, management includes general measures, drug treatment, and coronary artery revascularization if needed. Common antianginal drugs discussed are organic nitrates, calcium channel blockers, and beta-blockers. Unstable angina is treated with nitrates, beta-blockers, aspirin, and sometimes thrombolytics. Variant angina is managed with nitrates and calcium channel blockers.
Acute coronary syndrome (ACS) refers to conditions caused by reduced blood flow in the coronary arteries. This can be due to plaque buildup narrowing the arteries or plaque rupture leading to clot formation. ACS includes ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina (UA). Patients present with chest pain and may have ECG changes or elevated cardiac biomarkers. Treatment involves oxygen, nitroglycerin, aspirin, and morphine (MONA) along with long-term therapies like antiplatelets, beta-blockers, statins, and ACE inhibitors to prevent future events.
1) Acute coronary syndrome includes unstable angina and myocardial infarction, characterized by chest pain and elevated cardiac biomarkers.
2) Clinical features include severe, prolonged chest pain that may radiate to other areas, as well as syncope, vomiting, and arrhythmias.
3) Complications include heart failure, arrhythmias like ventricular fibrillation, cardiac rupture, and remodelling. Diagnosis involves ECG, cardiac enzymes, and angiography. Management focuses on reperfusion therapy, anticoagulation, and risk factor reduction.
NSTE-ACS (Non-ST-elevation acute coronary syndromes) describes conditions like unstable angina and NSTEMI characterized by reduced blood flow without persistent ST elevation. It is usually caused by partially occlusive thrombi forming on atherosclerotic plaques or arterial walls. Diagnosis involves chest pain symptoms and elevated cardiac biomarkers. Treatment focuses on anti-ischemic drugs, antithrombotic therapies, risk factor modification, and sometimes revascularization. Prinzmetal's variant angina involves coronary artery spasms causing transient chest pain and ST elevation.
The document provides information on myocardial infarction (MI or heart attack) including definitions, causes, pathophysiology, clinical manifestations, diagnostic tests, treatment, nursing management, and patient education. It defines MI as myocardial cell death due to prolonged ischemia. The main cause is sudden blockage of the coronary artery by a blood clot, causing irreversible damage to heart muscle. Clinical manifestations may include chest pain, shortness of breath, nausea, and changes in vital signs. Diagnostic tests include electrocardiogram, cardiac enzymes, and echocardiogram. Treatment focuses on reperfusion, reducing oxygen demand on the heart, and preventing complications. Nursing management involves monitoring for complications, relieving symptoms, promoting perfusion and respiratory function
The document discusses refractory angina, a condition where chest pain persists despite optimal medical therapy and invasive procedures. It describes various treatment options for chronic angina when standard therapies fail, including ranolazine which inhibits the late sodium current as a new potential antianginal option.
Stable angina is chest pain caused by plaque buildup in the coronary arteries that reduces blood flow during physical exertion. Unstable angina involves chest pain at rest that is a sign that plaques are rupturing. A STEMI occurs when a plaque rupture causes a complete blockage, lacking oxygen to heart muscle. Diagnosis involves EKG, cardiac enzymes, and angiography. Treatment focuses on lifestyle changes, medications, and procedures to restore blood flow and prevent future events. Stress testing helps evaluate risk and guide management.
Ischemic heart disease (IHD) is caused by an imbalance between myocardial oxygen supply and demand. The most common cause is atherosclerosis leading to decreased blood flow. IHD presents as stable angina, acute coronary syndrome (ACS), or sudden cardiac death. ACS includes ST-elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), and unstable angina (UA). STEMI is diagnosed based on ECG changes and cardiac enzyme levels and requires emergency reperfusion therapy. Risk factors include age, family history, smoking, diabetes, hypertension, and dyslipidemia. Management involves antithrombotic therapy, anti-ischemic drugs, revascularization, and controlling cardiovascular risk factors
1. Acute coronary syndrome (ACS) encompasses unstable angina and myocardial infarction, and is caused by reduced blood flow in the coronary arteries, often due to atherosclerosis.
2. Clinical features of ACS include chest pain and discomfort, but it can also be "silent" in some high-risk groups. Diagnosis involves ECG, cardiac troponin levels, and coronary angiography.
3. Treatment depends on whether the ACS is STEMI (ST elevation on ECG) or NSTEMI/unstable angina. For STEMI, primary percutaneous coronary intervention is the treatment of choice if readily available to restore blood flow, along with dual antiplatelet therapy and antico
Anaesthetic Management of a Patient with Ischaemic Heart DiseaseZareer Tafadar
This document discusses the anaesthetic management of patients with ischemic heart disease undergoing non-cardiac surgery. It begins by defining ischemic heart disease and outlining its various manifestations including stable angina, unstable angina, and myocardial infarction. It then discusses preoperative evaluation and risk stratification of these patients, including medical history, physical exam, ECG, stress testing, and coronary angiography. Intraoperative management focuses on minimizing myocardial ischemia through beta-blockers, tight blood pressure control, and avoidance of tachycardia or hypotension.
ا.د/شريف مختار
Acute coronary syndrome management
المحاضرة التي قدمت يوم الاربعاء 9 ابريل 2014 في دار الحكمة بالقاهرة
من فعاليات مشروع اعداد طبيب حكيم ناجح بالتعاون مع معتمد باتحاد الاطباء العرب
و ضمن موديول الطوارئ و التخدير و العناية المركزة
Similar to ACUTE MYOCARDIA INFARCTION ISCHEMIA MI Draz MY (20)
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
The skin is the largest organ and its health plays a vital role among the other sense organs. The skin concerns like acne breakout, psoriasis, or anything similar along the lines, finding a qualified and experienced dermatologist becomes paramount.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
3. RISK FACTORS AND PATHOGENESIS OF ATHEROMATOUS LESIONS OF ARTERIES.
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10. V.TACH.,ASYSTOLE,MASSIVE MI SUDDEN DEATH ALTERED CONDUCTION DUE TO ISCH.OR INFARCTION ARRYTHMIA MYOCARDIAL DYSFUNCTIONDUE TO INFARCTION OR ISCH. HEART FAILURE MYONECROSIS DUE TO ACUTE ISCH. MI DYNAMIC CORONARY OBSTRUCTION UNSTABLE ANGINA FIXED CORONARY ATHEROMATOUS LESION STABLE ANGINA CORONARY HEART DISEASE : CLINICAL MANIFESTATIONS AND PROBLEMS
72. Definite ACS Possible ACS (–) ECG; Normal biomarkers Observe; repeat ECG, markers at 4-8 hrs No recurrent pain; (–) follow-up studies Recurrent pain; (+) follow-up studies Stress test; LV function if ischemia (–) test: outpt follow-up (+) test Admit, Use Acute Ischemia Pathway ST Use MI Guidelines No ST ST-T ’s, chest pain, markers Symptoms Suggestive of ACS
73. Emergency Room Triage of Patients with Acute Chest Pain by Means of Rapid Testing for Cardiac Troponin T or Troponin I Christian W. Hamm, M.D., Britta U. Goldmann, M.D., Christopher Heeschen, M.D., Georg Kreymann, M.D., Jürgen Berger, Ph.D., and Thomas Meinertz, M.D. NEJM,Volume 337:1648-1653, Number 23 December 4, 1997 773 consecutive patients who had had acute chest pain for less than 12 hours without ST-segment elevation on their electrocardiograms, troponin T and troponin I status (positive or negative) was determined at least twice by sensitive, qualitative bedside tests based on the use of specific monoclonal antibodies.
74. Conclusions Bedside tests for cardiac-specific troponins are highly sensitive for the early detection of myocardial-cell injury in acute coronary syndromes. Negative test results are associated with low risk and allow rapid and safe discharge of patients with an episode of acute chest pain from the emergency room. 70 =22 % 44 =94 % 123 =16 % Tn.T +VE 114 =36 % 47 =100% 171 =22% Tn.I +VE 315 47 773 NO. UNSTABLE ANGINA MI.PATIENTS TOTAL PATIENTS
75. Missed Diagnoses of Acute Cardiac Ischemia in the Emergency Department. Pope ET AL. Volume 342:1163-1170, Number 16, NEJM April 20, 2000
76. Missed Diagnoses of Acute Cardiac Ischemia in the Emergency Department. Pope ET AL. Volume 342:1163-1170, Number 16, NEJM April 20, 2000 55 NON CARDIAC 21 NON ISCH.CARDIAC 6 STABLE ANGINA 9 UNSTABLE ANGINA 8 MI 17 ACUTE CARDIAC ISCH. % FROM TOTAL TOTAL NO.=10,689
77. 2.3% 22 966 UNSTABLE ANGINA 2.1% 19 889 ACUTE MI % OF TOTAL DISCHARGE FROM ED NO.
78. It appears that the incidence of missed diagnoses of acute cardiac ischemia in the emergency department may be reduced by: 1- Interpreting the electrocardiogram more accurately. 2- Addressing clinical factors or preconceptions that obscure the recognition of acute myocardial infarction and unstable angina in women and nonwhite patients. 3- Considering the possibility that acute cardiac ischemia may be present in patients with chief symptoms other than chest pain. 4- Assessing recent changes in the clinical course of angina more carefully.
In-stent restenosis is a proliferative disease disorder that leads to the phenomenon of late loss. In stetnting, a late loss of between .00 and 1 mm usually occurs. This leads to a significant reduction of luminal area of a stent. Late loss can result in up to a 56% reduction in the cross-sectional area in the average 3 mm vessel. In smaller vessels, the area obstruction is more severe with late loss contributing up to a 75% reduction in cross sectional area.
Algorithms can be used to detail the appropriate therapies in practice. The guidelines use the same basic algorithm. The process is very dynamic and all aspects need to be considered. Evaluate the patient Determine if the patient has ACS or possible ACS Interpret the ECG and bio-markers Observe the patient Repeat measurements Some patients may present as troponin negative but over time become troponin positive without any other symptoms.