The document summarizes the main characters in William Shakespeare's play Macbeth. It describes the Three Witches who prophesize that Macbeth will become king and cause his downfall. It outlines Macbeth's descent into tyranny after he murders King Duncan. Lady Macbeth encourages the murder and later shows signs of guilt. Banquo and his son Fleance are also targets as the Witches foretold Banquo's descendants would be kings.