This paper proposes a novel temporal event matrix representation (TEMR) framework to perform temporal signature mining from longitudinal event data. TEMR represents event data as a spatial-temporal matrix, where one dimension is event type and the other is time. A doubly sparse convolutional matrix approximation is used to detect latent signatures in the data. The approach is validated on synthetic and electronic health record data, showing it can scale to large datasets and detect interpretable signatures.
Our vision for the selective re-computation of genomics pipelines in reaction to changes to tools and reference datasets.
How do you prioritise patients for re-analysis on a given budget?
Talk given at TAPP'16 (Theory and Practice of Provenance), June 2016, paper is here:
https://arxiv.org/abs/1604.06412
Abstract:
The cost of deriving actionable knowledge from large datasets has been decreasing thanks to a convergence of positive factors:
low cost data generation, inexpensively scalable storage and processing infrastructure (cloud), software frameworks and tools for massively distributed data processing, and parallelisable data analytics algorithms.
One observation that is often overlooked, however, is that each of these elements is not immutable, rather they all evolve over time.
As those datasets change over time, the value of their derivative knowledge may decay, unless it is preserved by reacting to those changes. Our broad research goal is to develop models, methods, and tools for selectively reacting to changes by balancing costs and benefits, i.e. through complete or partial re-computation of some of the underlying processes.
In this paper we present an initial model for reasoning about change and re-computations, and show how analysis of detailed provenance of derived knowledge informs re-computation decisions.
We illustrate the main ideas through a real-world case study in genomics, namely on the interpretation of human variants in support of genetic diagnosis.
Your data won’t stay smart forever:exploring the temporal dimension of (big ...Paolo Missier
Much of the knowledge produced through data-intensive computations is liable to decay over time, as the underlying data drifts, and the algorithms, tools, and external data sources used for processing change and evolve. Your genome, for example, does not change over time, but our understanding of it does. How often should be look back at it, in the hope to gain new insight e.g. into genetic diseases, and how much does that cost when you scale re-analysis to an entire population?
The "total cost of ownership” of knowledge derived from data (TCO-DK) includes the cost of refreshing the knowledge over time in addition to the initial analysis, but is often not a primary consideration.
The ReComp project aims to provide models, algorithms, and tools to help humans understand TCO-DK, i.e., the nature and impact of changes in data, and assess the cost and benefits of knowledge refresh.
In this talk we try and map the scope of ReComp, by giving a number of patterns that cover typical analytics scenarios where re-computation is appropriate. We specifically describe two such scenarios, where we are conducting small scale, proof-of-concept ReComp experiments to help us sketch the general ReComp architecture. This initial exercise reveals a multiplicity of problems and research challenges, which will inform the rest of the project
Our vision for the selective re-computation of genomics pipelines in reaction to changes to tools and reference datasets.
How do you prioritise patients for re-analysis on a given budget?
Talk given at TAPP'16 (Theory and Practice of Provenance), June 2016, paper is here:
https://arxiv.org/abs/1604.06412
Abstract:
The cost of deriving actionable knowledge from large datasets has been decreasing thanks to a convergence of positive factors:
low cost data generation, inexpensively scalable storage and processing infrastructure (cloud), software frameworks and tools for massively distributed data processing, and parallelisable data analytics algorithms.
One observation that is often overlooked, however, is that each of these elements is not immutable, rather they all evolve over time.
As those datasets change over time, the value of their derivative knowledge may decay, unless it is preserved by reacting to those changes. Our broad research goal is to develop models, methods, and tools for selectively reacting to changes by balancing costs and benefits, i.e. through complete or partial re-computation of some of the underlying processes.
In this paper we present an initial model for reasoning about change and re-computations, and show how analysis of detailed provenance of derived knowledge informs re-computation decisions.
We illustrate the main ideas through a real-world case study in genomics, namely on the interpretation of human variants in support of genetic diagnosis.
Your data won’t stay smart forever:exploring the temporal dimension of (big ...Paolo Missier
Much of the knowledge produced through data-intensive computations is liable to decay over time, as the underlying data drifts, and the algorithms, tools, and external data sources used for processing change and evolve. Your genome, for example, does not change over time, but our understanding of it does. How often should be look back at it, in the hope to gain new insight e.g. into genetic diseases, and how much does that cost when you scale re-analysis to an entire population?
The "total cost of ownership” of knowledge derived from data (TCO-DK) includes the cost of refreshing the knowledge over time in addition to the initial analysis, but is often not a primary consideration.
The ReComp project aims to provide models, algorithms, and tools to help humans understand TCO-DK, i.e., the nature and impact of changes in data, and assess the cost and benefits of knowledge refresh.
In this talk we try and map the scope of ReComp, by giving a number of patterns that cover typical analytics scenarios where re-computation is appropriate. We specifically describe two such scenarios, where we are conducting small scale, proof-of-concept ReComp experiments to help us sketch the general ReComp architecture. This initial exercise reveals a multiplicity of problems and research challenges, which will inform the rest of the project
Securing Broker-Less Publish/Subscribe Systems Using Identity-Based EncryptionJPINFOTECH JAYAPRAKASH
Securing Broker-Less Publish/Subscribe Systems Using Identity-Based Encryption
To get this project in ONLINE or through TRAINING Sessions, Contact:JP INFOTECH, Old No.31, New No.86, 1st Floor, 1st Avenue, Ashok Pillar, Chennai -83.
Landmark: Next to Kotak Mahendra Bank.
Pondicherry Office: JP INFOTECH, #45, Kamaraj Salai, Thattanchavady, Puducherry -9.
Landmark: Next to VVP Nagar Arch.
Mobile: (0) 9952649690 , Email: jpinfotechprojects@gmail.com, web: www.jpinfotech.org
Influence of time and length size feature selections for human activity seque...ISA Interchange
In this paper, Viterbi algorithm based on a hidden Markov model is applied to recognize activity sequences from observed sensors events. Alternative features selections of time feature values of sensors events and activity length size feature values are tested, respectively, and then the results of activity sequences recognition performances of Viterbi algorithm are evaluated. The results show that the selection of larger time feature values of sensor events and/or smaller activity length size feature values will generate relatively better results on the activity sequences recognition performances.
Securing Broker-Less Publish/Subscribe Systems Using Identity-Based EncryptionJPINFOTECH JAYAPRAKASH
Securing Broker-Less Publish/Subscribe Systems Using Identity-Based Encryption
To get this project in ONLINE or through TRAINING Sessions, Contact:JP INFOTECH, Old No.31, New No.86, 1st Floor, 1st Avenue, Ashok Pillar, Chennai -83.
Landmark: Next to Kotak Mahendra Bank.
Pondicherry Office: JP INFOTECH, #45, Kamaraj Salai, Thattanchavady, Puducherry -9.
Landmark: Next to VVP Nagar Arch.
Mobile: (0) 9952649690 , Email: jpinfotechprojects@gmail.com, web: www.jpinfotech.org
Influence of time and length size feature selections for human activity seque...ISA Interchange
In this paper, Viterbi algorithm based on a hidden Markov model is applied to recognize activity sequences from observed sensors events. Alternative features selections of time feature values of sensors events and activity length size feature values are tested, respectively, and then the results of activity sequences recognition performances of Viterbi algorithm are evaluated. The results show that the selection of larger time feature values of sensor events and/or smaller activity length size feature values will generate relatively better results on the activity sequences recognition performances.
In recent years, the complex event processing technology has been used to process the VANET’s temporal
and spatial event streams. However, we usually cannot get the accurate data because the device sensing
accuracy limitations of the system. We only can get the uncertain data from the complex and limited
environment of the VANET. Because the VANET’s event streams are consist of the uncertain data, so they
are also uncertain. How effective to express and process these uncertain event streams has become the core
issue for the VANET system. To solve this problem, we propose a novel complex event query language
PSTeCEQL (probabilistic spatio-temporal constraint event query language). Firstly, we give the definition
of the possible world model of VANET’s uncertain event streams. Secondly, we propose an event query
language PSTeCEQL and give the syntax and the operational semantics of the language. Finally, we
illustrate the validity of the PSTeCEQL by an example.
PSTECEQL: A NOVEL EVENT QUERY LANGUAGE FOR VANET’S UNCERTAIN EVENT STREAMSijfcstjournal
In recent years, the complex event processing technology has been used to process the VANET’s temporal
and spatial event streams. However, we usually cannot get the accurate data because the device sensing
accuracy limitations of the system. We only can get the uncertain data from the complex and limited
environment of the VANET. Because the VANET’s event streams are consist of the uncertain data, so they
are also uncertain. How effective to express and process these uncertain event streams has become the core
issue for the VANET system. To solve this problem, we propose a novel complex event query language
PSTeCEQL (probabilistic spatio-temporal constraint event query language). Firstly, we give the definition
of the possible world model of VANET’s uncertain event streams. Secondly, we propose an event query
language PSTeCEQL and give the syntax and the operational semantics of the language. Finally, we
illustrate the validity of the PSTeCEQL by an example.
A LIGHT-WEIGHT DISTRIBUTED SYSTEM FOR THE PROCESSING OF REPLICATED COUNTER-LI...ijdpsjournal
In order to increase availability in a distributed system some or all of the data items are replicated and
stored at separate sites. This is an issue of key concern especially since there is such a proliferation of
wireless technologies and mobile users. However, the concurrent processing of transactions at separate
sites can generate inconsistencies in the stored information. We have built a distributed service that
manages updates to widely deployed counter-like replicas. There are many heavy-weight distributed
systems targeting large information critical applications. Our system is intentionally, relatively lightweight
and useful for the somewhat reduced information critical applications. The service is built on our
distributed concurrency control scheme which combines optimism and pessimism in the processing of
transactions. The service allows a transaction to be processed immediately (optimistically) at any
individual replica as long as the transaction satisfies a cost bound. All transactions are also processed in a
concurrent pessimistic manner to ensure mutual consistency
— The healthcare industry is considered one of the
largest industry in the world. The healthcare industry is same as
the medical industries having the largest amount of health related
and medical related data. This data helps to discover useful
trends and patters that can be used in diagnosis and decision
making. Clustering techniques like K-means, D-streams,
COBWEB, EM have been used for healthcare purposes like heart
disease diagnosis, cancer detection etc. This paper focuses on the
use of K-means and D-stream algorithm in healthcare. This
algorithms were used in healthcare to determine whether a
person is fit or unfit and this fitness decision was taken based on
his/her historical and current data. Both the clustering
algorithms were analyzed by applying them on patients current
biomedical historical databases, this analysis depends on the
attributes like peripheral blood oxygenation, diastolic arterial
blood pressure, systolic arterial blood pressure, heart rate,
heredity, obesity, and this fitness decision was taken based on
his/her historical and current data. Both the clustering
algorithms were analyzed by applying them on patients current
biomedical historical databases, this analysis depends on the
attributes like peripheral blood oxygenation, diastolic arterial
blood pressure, systolic arterial blood pressure, heart rate,
heredity, obesity, cigarette smoking. By analyzing both the
algorithm it was found that the Density-based clustering
algorithm i.e. the D-stream algorithm proves to give more
accurate results than K-means when used for cluster formation of
historical biomedical data. D-stream algorithm overcomes
drawbacks of K-means algorithm
During seizures, different types of communication between different parts of the brain are characterized by many state of the art connectivity measures. We propose to employ a set of undirected (spectral matrix, the inverse of the spectral matrix, coherence, partial coherence, and phase-locking value) and directed features (directed coherence, the partial directed coherence) to detect seizures using a deep neural network. Taking our data as a sequence of ten sub-windows, an optimal deep sequence learning architecture using attention, CNN, BiLstm, and fully connected neural networks is designed to output the detection label and the relevance of the features. The relevance is computed using the weights of the model in the activation values of the receptive fields at a particular layer. The best model resulted in 97.03% accuracy using balanced MIT-BIH data subset. Finally, an analysis of the relevance of the features is reported.
Maximum Correntropy Based Dictionary Learning Framework for Physical Activity...sherinmm
Due to its symbolic role in ubiquitous health monitoring,
physical activity recognition with wearable body sensors has been in the
limelight in both research and industrial communities. Physical activity
recognition is difficult due to the inherent complexity involved with different
walking styles and human body movements. Thus we present a
correntropy induced dictionary pair learning framework to achieve this
recognition. Our algorithm for this framework jointly learns a synthesis
dictionary and an analysis dictionary in order to simultaneously perform
signal representation and classification once the time-domain features
have been extracted. In particular, the dictionary pair learning algorithm
is developed based on the maximum correntropy criterion, which
is much more insensitive to outliers. In order to develop a more tractable
and practical approach, we employ a combination of alternating direction
method of multipliers and an iteratively reweighted method to approximately
minimize the objective function. We validate the effectiveness of
our proposed model by employing it on an activity recognition problem
and an intensity estimation problem, both of which include a large number
of physical activities from the recently released PAMAP2 dataset.
Experimental results indicate that classifiers built using this correntropy
induced dictionary learning based framework achieve high accuracy by
using simple features, and that this approach gives results competitive
with classical systems built upon features with prior knowledge.
International Journal of Engineering Research and DevelopmentIJERD Editor
Electrical, Electronics and Computer Engineering,
Information Engineering and Technology,
Mechanical, Industrial and Manufacturing Engineering,
Automation and Mechatronics Engineering,
Material and Chemical Engineering,
Civil and Architecture Engineering,
Biotechnology and Bio Engineering,
Environmental Engineering,
Petroleum and Mining Engineering,
Marine and Agriculture engineering,
Aerospace Engineering.
It is widely agreed that complex diseases are typically caused by joint effects of multiple genetic variations, rather than a single genetic variation. Multi-SNP interactions, also known as epistatic interactions, have the potential to provide information about causes of complex diseases, and build on GWAS studies that look at associations between single SNPs and phenotypes. However, epistatic analysis methods are both computationally expensive, and have limited accessibility for biologists wanting to analyse GWAS datasets due to being command line based. Here we present APPistatic, a prototype desktop version of a pipeline for epistatic analysis of GWAS datasets. his application combines ease-of-use, via a GUI, with accelerated implementation of BOOST and FaST-LMM epistatic analysis methods.
A Wearable Accelerometer System for Unobtrusive Monitoring of Parkinson’s Dis...Michael J. Montgomery
Abstract: Parkinson’s disease is a complex condition currently monitored at home with paper diaries which rely on subjective and unreliable assessment of motor function at nonstandard time intervals. We present an innovative wearable and unobtrusive monitoring system for patients which can help provide physicians with significantly improved assessment of patients’ responses to drug therapies and lead to better-targeted treatment regimens. In this paper we describe the algorithmic development of the system and an evaluation in patients for assessing the onset and duration of advanced PD motor symptoms.
We developed a real-time, visual analytics tool for clinical decision support. The system expands the “recall of past experience” approach that a provider (physician) uses to formulate a course of action for a given patient. By utilizing Big-Data techniques, we enable the provider to recall all similar patients from an institution’s electronic medical record (EMR) repository, to explore “what-if” scenarios, and to collect these evidence-based cohorts for future statistical validation and pattern mining.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
A framework for mining signatures from event sequences and its applications in healthcare data
1. A Framework for Mining Signatures from Event Sequences
and Its Applications in Healthcare Data
ABSTRACT:
This paper proposes a novel temporal knowledge representation and learning
framework to perform large-scale temporal signature mining of longitudinal
heterogeneous event data. The framework enables the representation, extraction,
and mining of high order latent event structure and relationships within single and
multiple event sequences. The proposed knowledge representation maps the
heterogeneous event sequences to a geometric image by encoding events as a
structured spatial-temporal shape process. We present a doubly constrained
convolutional sparse coding framework that learns interpretable and shift-invariant
latent temporal event signatures. We show how to cope with the sparsity in the data
as well as in the latent factor model by inducing a double sparsity constraint on the
β-divergence to learn an over complete sparse latent factor model. A novel
stochastic optimization scheme performs large-scale incremental learning of
group-specific temporal event signatures. We validate the framework on synthetic
data and on an electronic health record dataset.
2. EXISTING SYSTEM:
Finding latent temporal signatures is important in many domains as they encode
temporal concepts such as event trends, episodes, cycles, and abnormalities. For
example, in the medical domain latent event signatures facilitate decision support
for patient diagnosis, prognosis, and management. In the surveillance domain
temporal event signatures aid in detection of suspicious events at specific
locations. Of particular interest is the temporal aspect of information hidden in
event data that may be used to perform intelligent reasoning and inference about
the latent relationships between event entities over time. An event entity can be a
person, an object, or a location in time. For instance, in the medical domain a
patient would be considered as an event entity, where visits to the doctor’s office
would be considered as events.
DISADVANTAGES OF EXISTING SYSTEM:
Temporal event signature mining for knowledge discovery is a difficult problem.
In this regard, several problems need to be addressed:
3. 1. The EKR(Event Knowledge Representation) should handle the time-invariant
representation of multiple event entities as two event entities can be considered
similar if they contain the same temporal signatures at different time intervals or
locations,
2. EKR should be flexible to jointly represent different types of event structure
such as single multivariate events and event intervals to allow a rich representation
of complex event relationships,
3. EKR should be scalable to support analysis and inference on large-scale
databases, and
4. EKR should be sparse to enable interpretability of the learned signatures by
humans.
PROPOSED SYSTEM:
This paper proposes a novel Temporal Event Matrix Representation (TEMR) and
learning framework to perform temporal signature mining for large-scale
longitudinal and heterogeneous event data. Basically, our TEMR framework
represents the event data as a spatial-temporal matrix, where one dimension of the
matrix corresponds to the type of the events and the other dimension represents the
time information. In this case, if event i happened at time j with value k, then the
4. (i,j)th element of the matrix is k. This is a very flexible and intuitive framework for
encoding the temporal knowledge information contained in the event sequences.
To improve the scalability of the proposed approach, we further developed an
online updating technology. Finally, the effectiveness of the proposed algorithm is
validated on a real-world healthcare dataset.
ADVANTAGES OF PROPOSED SYSTEM:
First, on the knowledge representation level, TEMR provides a visual
matrix-based representation of complicated event data composed of different
types of events as well as event intervals, which supports the joint
representation of both continuous and discrete valued data.
Second, on the algorithmic level, we propose a doubly sparse convolutional
matrix approximation-based formulation for detecting the latent signatures
contained in the datasets. Moreover, we derive a multiplicative updates
procedure to solve the problem and proved theoretically its convergence. We
further propose a novel stochastic optimization scheme for large-scale
longitudinal event signature mining of multiple event entities in a group. We
demonstrate that appropriate normalization constraints on the sparse latent
factor model allow for automatic rank determination.
Third, on the experimental level, we have validated our approach using both
synthetic data and a real-world Electronic Health Records (EHRs) dataset
5. which contains the longitudinal medical records of over 20k patients over
one year period. We report the results on the detected signatures,
convergence behavior of the algorithm, and the final matrix reconstruction
errors.
ALGORITHMS USED:
Algorithm 1. OSC-NMF (Individual)
Algorithm 2. OSC-NMF (Group)
Algorithm 1- OSC-NMF (Individual)
Require: X;F; G; r; T; 𝛽; λ
Ensure: F ≥0;G ≥0
1: Initialize F; G
2: for i = 1 to T do
3: Update F
4: Update G
5: if (converged) then
6: break
7: end if
8: end for
9: return Ro= {W;H}
7. Hard Disk - 20 GB
Key Board - Standard Windows Keyboard
Mouse - Two or Three Button Mouse
Monitor - SVGA
SOFTWARE CONFIGURATION:-
Operating System : Windows XP
Programming Language : JAVA
Java Version : JDK 1.6 & above.
REFERENCE:
Fei Wang, Member, IEEE, Noah Lee, Jianying Hu, Senior Member, IEEE, Jimeng
Sun, Shahram Ebadollahi, Member, IEEE, and Andrew F. Laine, Fellow, IEEE-
“A Framework for Mining Signatures from Event Sequences and Its Applications
in Healthcare Data”, IEEE TRANSACTIONS ON PATTERN ANALYSIS
AND MACHINE INTELLIGENCE, VOL. 35, NO. 2, FEBRUARY2013