3 ερμηνευτικά κριτήρια σε gram θετικά βακτήριαEKMED
This document provides guidelines for antimicrobial susceptibility testing of Gram-positive bacteria using disk diffusion and MIC methods according to EUCAST and CLSI standards. It discusses testing and interpreting results for staphylococci, enterococci, and streptococcus pneumoniae. Breakpoints and interpretive criteria are provided for numerous antimicrobial agents including beta-lactams, glycopeptides, macrolides, lincosamides and streptogramins. Expert rules are also described for interpreting certain antimicrobial-pathogen combinations.
10 στρατηγική αντιμετώπισης λοιμώξεων από πολυανθεκτικάEKMED
- The document discusses guidelines for reporting antibiotic susceptibility results for Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs). It recommends reporting results based on minimum inhibitory concentration (MIC) values rather than the presence of an ESBL, with warnings for certain antibiotic combinations for non-urinary infections.
- Empirical therapy for critically ill patients with ESBL infections should use carbapenems. Definitive therapy can use cephalosporins or beta-lactam/beta-lactamase inhibitor combinations if the MIC is ≤0.25 μg/ml and the infection is not bloodstream-related.
- Studies show higher mortality with ESBL infections treated
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