The document discusses the health benefits of rice bran oil (RBO). It notes that RBO contains antioxidants like tocopherols, tocotrienols, phytosterols, and γ-oryzanol that can lower cholesterol and blood pressure. Studies show RBO may reduce the risk of cardiovascular disease and help manage diabetes. Clinical trials found RBO lowers total and LDL cholesterol in both healthy and hypercholesterolemic patients. The document concludes RBO and its blend with other oils may help control blood glucose levels and oxidative stress in patients with type 2 diabetes.
1) Rice bran oil contains numerous bioactive compounds that provide various health benefits. It is rich in phytosterols, tocopherols, tocotrienols, polyphenols, and gamma-oryzanol which have anti-oxidative, anti-inflammatory, cholesterol-lowering, and other nutraceutical functions.
2) The bioactive compounds in rice bran oil have been shown to reduce risk of heart disease, obesity, cancer, and other chronic diseases through their anti-oxidative, anti-inflammatory, and hypolipidemic properties.
3) Further research is needed to fully understand the nutraceutical mechanisms of rice bran oil and maximize its health benefits through synerg
Rice bran oil is a unique cooking oil produced from rice bran that has desirable fatty acid ratios and contains beneficial compounds like Oryzanol and Tocotrienols. Several studies have found that rice bran oil and its components have positive health effects such as lowering cholesterol and blood pressure, improving diabetes and liver health, reducing inflammation, and protecting against neurodegenerative diseases. Its ideal fatty acid profile and nutrients make it a healthier choice for cooking oil than other common oils.
1. Rice bran oil is a vegetable oil produced from rice bran as a byproduct of rice milling.
2. The first rice bran oil extraction plant in India was set up in 1964, and by 1990 there were many plants across major rice growing areas.
3. In the 1990s, physical refining processes were developed for rice bran oil in India to avoid losses of nutrients like oryzanol from chemical refining.
Dr Q's Ultra Pure Omega 3 is a fish oil supplement that provides 820 mg of omega-3 fatty acids per softgel. The fish oil is molecularly distilled to remove contaminants and increase the concentration of EPA and DHA. Research suggests omega-3 fatty acids support cardiovascular, brain, joint, and immune system health by promoting anti-inflammatory responses and maintaining healthy triglyceride and cholesterol levels. Dr Q's Ultra Pure Omega 3 undergoes a rigorous triple-phase molecular distillation process to maximize purity and ensure safety.
This document provides an overview of functional meat products. It defines functional foods and discusses opportunities and drivers for their development, including growing health issues. Meat can act as an excellent vehicle for delivering bioactive compounds. Strategies for developing functional meat products include modifying animal diets and feed to alter the fatty acid or nutrient composition of meat. Products can also be reformulated by reducing fat content, adding plant proteins, probiotics, dietary fiber, minerals, vitamins, or antioxidants. Unhealthy compounds like sodium can also be reduced. Functional meat products could help address health issues like obesity if their effects are substantiated in human studies.
Curcumin Capsules are prepared from pure herbal extract of Curcumin or Turmeric (Curcuma longa). Curcumin possess potent antioxidant properties, supports colon health and helps maintain a healthy cardiovascular system. Curcumin Capsules are helpful in health disorders such as Alzheimer’s disease, arthritis, cancer, gout and improve immunity in a natural way.
For More Detail Visit Us:- www.planetayurveda.com/curcumin-capsules.htm
1) Exercise without weight loss is associated with a 10-20% reduction in intra-abdominal fat and waist circumference, while exercise with weight loss leads to greater reductions of 30% in intra-abdominal fat and waist circumference.
2) Rimonabant, a CB1 receptor antagonist, was associated with 4.1-9% placebo-subtracted improvements in weight, waist circumference, HDL cholesterol, and triglycerides in clinical trials.
3) Lifestyle interventions emphasizing diet and exercise can reduce the risk of developing diabetes by 58% compared to 31% for metformin and 7% for placebo.
1. Phytosterols are plant compounds similar in structure to cholesterol that have shown promise in treating various cancers. Studies in animal models and cell cultures have found that phytosterol supplementation reduced tumor growth and progression of breast, prostate, colon and other cancers.
2. Mechanisms by which phytosterols may treat cancer include inducing apoptosis of cancer cells, reducing oxidative stress, decreasing inflammatory cytokines and angiogenesis to cancer cells. Doses of 300mg per day have shown benefits, though most Americans consume only 80mg daily.
3. Further research is still needed to better understand long term effects and interactions with drugs, but initial animal and cell studies provide evidence that phytosterols may be a potential dietary intervention
1) Rice bran oil contains numerous bioactive compounds that provide various health benefits. It is rich in phytosterols, tocopherols, tocotrienols, polyphenols, and gamma-oryzanol which have anti-oxidative, anti-inflammatory, cholesterol-lowering, and other nutraceutical functions.
2) The bioactive compounds in rice bran oil have been shown to reduce risk of heart disease, obesity, cancer, and other chronic diseases through their anti-oxidative, anti-inflammatory, and hypolipidemic properties.
3) Further research is needed to fully understand the nutraceutical mechanisms of rice bran oil and maximize its health benefits through synerg
Rice bran oil is a unique cooking oil produced from rice bran that has desirable fatty acid ratios and contains beneficial compounds like Oryzanol and Tocotrienols. Several studies have found that rice bran oil and its components have positive health effects such as lowering cholesterol and blood pressure, improving diabetes and liver health, reducing inflammation, and protecting against neurodegenerative diseases. Its ideal fatty acid profile and nutrients make it a healthier choice for cooking oil than other common oils.
1. Rice bran oil is a vegetable oil produced from rice bran as a byproduct of rice milling.
2. The first rice bran oil extraction plant in India was set up in 1964, and by 1990 there were many plants across major rice growing areas.
3. In the 1990s, physical refining processes were developed for rice bran oil in India to avoid losses of nutrients like oryzanol from chemical refining.
Dr Q's Ultra Pure Omega 3 is a fish oil supplement that provides 820 mg of omega-3 fatty acids per softgel. The fish oil is molecularly distilled to remove contaminants and increase the concentration of EPA and DHA. Research suggests omega-3 fatty acids support cardiovascular, brain, joint, and immune system health by promoting anti-inflammatory responses and maintaining healthy triglyceride and cholesterol levels. Dr Q's Ultra Pure Omega 3 undergoes a rigorous triple-phase molecular distillation process to maximize purity and ensure safety.
This document provides an overview of functional meat products. It defines functional foods and discusses opportunities and drivers for their development, including growing health issues. Meat can act as an excellent vehicle for delivering bioactive compounds. Strategies for developing functional meat products include modifying animal diets and feed to alter the fatty acid or nutrient composition of meat. Products can also be reformulated by reducing fat content, adding plant proteins, probiotics, dietary fiber, minerals, vitamins, or antioxidants. Unhealthy compounds like sodium can also be reduced. Functional meat products could help address health issues like obesity if their effects are substantiated in human studies.
Curcumin Capsules are prepared from pure herbal extract of Curcumin or Turmeric (Curcuma longa). Curcumin possess potent antioxidant properties, supports colon health and helps maintain a healthy cardiovascular system. Curcumin Capsules are helpful in health disorders such as Alzheimer’s disease, arthritis, cancer, gout and improve immunity in a natural way.
For More Detail Visit Us:- www.planetayurveda.com/curcumin-capsules.htm
1) Exercise without weight loss is associated with a 10-20% reduction in intra-abdominal fat and waist circumference, while exercise with weight loss leads to greater reductions of 30% in intra-abdominal fat and waist circumference.
2) Rimonabant, a CB1 receptor antagonist, was associated with 4.1-9% placebo-subtracted improvements in weight, waist circumference, HDL cholesterol, and triglycerides in clinical trials.
3) Lifestyle interventions emphasizing diet and exercise can reduce the risk of developing diabetes by 58% compared to 31% for metformin and 7% for placebo.
1. Phytosterols are plant compounds similar in structure to cholesterol that have shown promise in treating various cancers. Studies in animal models and cell cultures have found that phytosterol supplementation reduced tumor growth and progression of breast, prostate, colon and other cancers.
2. Mechanisms by which phytosterols may treat cancer include inducing apoptosis of cancer cells, reducing oxidative stress, decreasing inflammatory cytokines and angiogenesis to cancer cells. Doses of 300mg per day have shown benefits, though most Americans consume only 80mg daily.
3. Further research is still needed to better understand long term effects and interactions with drugs, but initial animal and cell studies provide evidence that phytosterols may be a potential dietary intervention
95% Curcumin Capsules in India- Health Benefits and Dosage- Best Anti Cancer ...Planet Ayurveda
Curcumin, the active compound in turmeric, has numerous health benefits including anti-inflammatory, anti-cancer, anti-diabetic, and anti-microbial properties. Studies show cancer rates are lower in India and other Asian countries where turmeric is commonly used as a spice. Curcumin works to prevent cancer development at multiple stages by inhibiting transcription factors like NF-kB that promote tumor growth and metastasis, as well as reducing inflammatory cytokines. Planet Ayurveda offers high-quality curcumin supplements made from turmeric extracts standardized to contain 95% curcuminoids.
Phytosterols for cancer treatment powerpointJosh Nooner
Phytosterols show promise for cancer treatment based on several animal, in vitro, and human studies. Animal studies found that phytosterol supplementation delayed breast cancer tumor onset and reduced prostate cancer growth. In vitro studies demonstrated that phytosterols increased cancer cell apoptosis, decreased proliferation, and increased tumor suppressor genes. A human epidemiological study associated higher phytosterol intake with a 50% reduced risk of lung cancer. Overall, the research suggests phytosterols may exert anticancer effects through reducing oxidative damage and preventing tumor growth and progression.
Pumpkin seed oil extracted from cucurbita maxima improves urinary disorder in...Younis I Munshi
This document summarizes a study that evaluated the effects of pumpkin seed oil extracted from Cucurbita maxima on urinary dysfunction in human overactive bladder. Forty-five subjects took 10 grams per day of pumpkin seed oil from C. maxima for 12 weeks. Urinary function was evaluated at baseline and after 6 and 12 weeks using the Overactive Bladder Symptom Score. The results showed that pumpkin seed oil from C. maxima significantly reduced OABSS scores after both 6 and 12 weeks, suggesting it may be effective for treating urinary disorders like overactive bladder in humans.
The document provides dietary recommendations for 4 groups:
1) A lactating woman aged 32 weighing 56kg: prescribed a 2500kcal diet with 75g protein and adequate vitamins and minerals.
2) A female medical student weighing 52kg: prescribed a 1900kcal diet with 52g protein and adequate vitamins and minerals.
3) A pregnant woman in her 2nd trimester weighing 55kg: prescribed a 2250kcal diet with 78g protein and adequate vitamins and minerals.
4) A clerk weighing 60kg: prescribed a 2730kcal diet with 60g protein and adequate vitamins and minerals.
Each dietary prescription includes specific food items and quantities to meet the nutritional needs.
The document provides an overview of the current status of nutrition labelling and claims in Malaysia. Key points include:
- Nutrition labelling is mandatory for over 50 categories of foods in Malaysia since 2005.
- Claims must be accompanied by full nutrition labelling.
- Permitted claims include nutrient content, comparative and function claims. Disease risk reduction claims are prohibited.
- There are criteria for labelling of mandatory and optional nutrients as well as conditions for certain nutrition claims.
- Approval of new claims involves review by expert committees and the Director General of Health.
This document contains spotters (short case studies) on various foods including cereals, pulses, nuts, and dairy. It provides details on the nutritional composition, properties, and recommended consumption of each food. For example, the wheat spotter discusses that it is higher in protein than rice but lower quality, and whole wheat is preferable to refined wheat. The milk spotter notes its protein and energy content per 100ml. The document aims to inform medical students and health professionals about essential nutrition information through concise spotters on individual food items.
enhancing the functionality of milk by dietary manipulationSharishKumar2
This document summarizes strategies to enhance the functionality of milk through dietary modification. It discusses:
1) What are functional foods and considerations for them, including that they are foods derived from natural ingredients that have a particular function when consumed as part of the daily diet.
2) Ways to increase certain nutrients and compounds in milk like conjugated linoleic acid, omega-3 fatty acids, selenium, and docosahexaenoic acid through feeding practices such as increasing intake of their precursors from pasture, plants, or supplements.
3) Research showing how dietary changes like adding oils, herbal extracts, or fish oil to cow feed can boost nutrients like CLA, omega-3s, and D
Pulses are an important source of protein in vegetarian diets, providing essential amino acids that cereals and grains lack. Proteins are needed for growth, tissue synthesis, digestive juices, hormones, and more. Pulses also provide energy and fiber. While protein quality varies, pulses have a net protein utilization of around 65 compared to egg protein. A table lists the nutrient contents of various pulses commonly consumed in India, such as Bengal gram, black gram, cowpea, and soybean. Pulses additionally contain vitamins and folic acid.
This document provides an overview of papaya, including its classification, origins, main active ingredients, health benefits, mechanisms of action, nutrition facts, and potential side effects. Papaya contains several proteolytic enzymes such as papain and chymopapain that aid in protein digestion. It also has antioxidant and anti-inflammatory properties that may help reduce risks of certain cancers and lower blood pressure and cholesterol. Potential side effects include skin irritation, increased bleeding risk when taken with blood thinners, and unsafe consumption during pregnancy or breastfeeding.
Dr Q's YeastMycin is a supplement formulated to support gastrointestinal health and microbial balance through a blend of ingredients including oregano extract, sodium caprylate, ginger, turmeric, and olive leaf extract. These ingredients have been studied and have mechanisms to support antioxidant activity, healthy gastrointestinal flora, digestion, and immune function. The comprehensive formula is designed to maintain gastrointestinal tract health and microflora balance while supporting antioxidant systems and tissue health.
AHS13 Jeff Leighton — The Role of Omega 3 Oils in the Treatment of Chronic In...Ancestral Health Society
Inflammation is associated with virtually all chronic, progressive diseases such as heart disease, vascular disease, asthma, IBS, autoimmune diseases, rheumatoid arthritis, osteoarthritis and even chronic neurological diseases such as Alzheimer’s disease. The signals that induce inflammation are multifactorial. High dose omega 3 has the potential to be as or more effective than pharmaceutical therapies. We will report on a series of omega 3 studies that compared dose response, dose timing, (e.g. once a day or twice a day), and food intake (with or without) in four separate cohorts.
This document provides information about Tegreen 97, a green tea extract dietary supplement produced by Pharmanex. It contains 97% polyphenols, the highest level in the industry, equivalent to drinking 7 cups of green tea. Research shows green tea's polyphenols, especially EGCg, protect cells from damage by acting as antioxidants, preventing lipid peroxidation, and inducing programmed cell death in abnormal cells. Tegreen 97 supports general well-being and cellular health to help reduce risks of serious diseases like cancer.
During the webinar, Sophie covers in depth the new Restore and Maintain treatment protocol, including the unique benefits of a combination of strength, concentration and dose for providing the fastest acting, most effective, therapeutic omega-3 intervention strategy to support your clients’ health. She details how to use the Pharmepa range to provide truly personalised nutrition support to meet your clients’ individual omega-3 needs. After explaining the benefits of the protocol as a whole, Sophie covers the key conditions Pharmepa has been designed to support and the dosing guidelines for clients with these concerns.
This document summarizes key nutrients that provide calories - carbohydrates, fats, and proteins. It describes the sources and functions of carbohydrates including sugars, starches, and fiber. It also discusses the different types of fats including saturated, unsaturated, and trans fats. Finally, it covers the sources and functions of protein as well as complete and incomplete protein sources and dietary recommendations.
Role of Phytoestrogens in Breast CancerNeha Dhiman
because of the side effects caused by the synthetic drugs and therapies, it is better to rely on natural products. natural products has lot of benefits and risk is less.
This document discusses nutraceuticals and probiotics. It defines nutraceuticals as foods that provide medical benefits for preventing and treating diseases. Examples mentioned include foods high in fatty acids, polyphenols, carotenoids, and dietary fiber. Probiotics are live microorganisms that benefit digestive health. Prebiotics are non-digestible foods that promote probiotic growth. The document outlines the history of probiotics and their roles in supporting immunity, digestion, and chronic illness prevention. Common probiotic sources like yogurt and kefir are noted. Research on using probiotics for conditions like obesity, osteoporosis, and cancer is also summarized.
Black cumin oil contains the potent antioxidant thymoquinone. Studies show thymoquinone has anti-inflammatory and analgesic properties, and helps stimulate bile production and fat metabolism in the liver. Black cumin is also high in essential fatty acids and vitamins that are beneficial for brain function, blood pressure, and immune defenses. Research has found black cumin oil to have anti-oxidant, anti-inflammatory, and potential anti-cancer effects. Black cumin nourishes the body, aids digestion, and promotes skin and immune health.
Dr. Robert Rutledge authored a paper on how bile acid depletion through gastrointestinal bypass decreases HbA1c, serum glucose, and improves insulin sensitivity. The paper reviews literature showing that bile acids are signaling molecules that regulate glucose, lipid, and energy metabolism. Studies demonstrate that decreasing bile acid pools through procedures like duodenal bypass results in lower blood glucose and better insulin sensitivity. Manipulating bile acid levels may help treat diabetes.
This document provides information on the management of dyslipidemia. It discusses non-pharmacological treatment including lifestyle changes like exercise and diet. Pharmacological treatments for dyslipidemia are also outlined, including statins, fibrates, bile acid resins, nicotinic acid derivatives, cholesterol absorption inhibitors, and fish oil supplements. The mechanisms of action, dosages, adverse effects and patient counseling points are described for each drug class.
This document provides information on hyperlipidemia and dyslipidemia, including their causes, risk factors, diagnostic testing, and treatment options. It notes that disorders of lipoprotein metabolism that increase LDL-C and total cholesterol while decreasing HDL-C raise cardiovascular disease risk. Genetic and environmental factors both contribute to primary dyslipidemia. Lifestyle changes and lipid-lowering medications, particularly statins, are used to treat abnormal lipid levels and reduce disease risk. The main drug classes for treatment include statins, fibrates, bile acid sequestrants, cholesterol absorption inhibitors, and niacin.
This webinar is designed to teach practitioners about how to use and recommend the Igennus cardiovascular health treatment protocol for maximum results in your clients. We will cover the evidence for the use of the nutrients within the protocol and provide the recommended dosing regime for a range of cardiovascular health concerns.
95% Curcumin Capsules in India- Health Benefits and Dosage- Best Anti Cancer ...Planet Ayurveda
Curcumin, the active compound in turmeric, has numerous health benefits including anti-inflammatory, anti-cancer, anti-diabetic, and anti-microbial properties. Studies show cancer rates are lower in India and other Asian countries where turmeric is commonly used as a spice. Curcumin works to prevent cancer development at multiple stages by inhibiting transcription factors like NF-kB that promote tumor growth and metastasis, as well as reducing inflammatory cytokines. Planet Ayurveda offers high-quality curcumin supplements made from turmeric extracts standardized to contain 95% curcuminoids.
Phytosterols for cancer treatment powerpointJosh Nooner
Phytosterols show promise for cancer treatment based on several animal, in vitro, and human studies. Animal studies found that phytosterol supplementation delayed breast cancer tumor onset and reduced prostate cancer growth. In vitro studies demonstrated that phytosterols increased cancer cell apoptosis, decreased proliferation, and increased tumor suppressor genes. A human epidemiological study associated higher phytosterol intake with a 50% reduced risk of lung cancer. Overall, the research suggests phytosterols may exert anticancer effects through reducing oxidative damage and preventing tumor growth and progression.
Pumpkin seed oil extracted from cucurbita maxima improves urinary disorder in...Younis I Munshi
This document summarizes a study that evaluated the effects of pumpkin seed oil extracted from Cucurbita maxima on urinary dysfunction in human overactive bladder. Forty-five subjects took 10 grams per day of pumpkin seed oil from C. maxima for 12 weeks. Urinary function was evaluated at baseline and after 6 and 12 weeks using the Overactive Bladder Symptom Score. The results showed that pumpkin seed oil from C. maxima significantly reduced OABSS scores after both 6 and 12 weeks, suggesting it may be effective for treating urinary disorders like overactive bladder in humans.
The document provides dietary recommendations for 4 groups:
1) A lactating woman aged 32 weighing 56kg: prescribed a 2500kcal diet with 75g protein and adequate vitamins and minerals.
2) A female medical student weighing 52kg: prescribed a 1900kcal diet with 52g protein and adequate vitamins and minerals.
3) A pregnant woman in her 2nd trimester weighing 55kg: prescribed a 2250kcal diet with 78g protein and adequate vitamins and minerals.
4) A clerk weighing 60kg: prescribed a 2730kcal diet with 60g protein and adequate vitamins and minerals.
Each dietary prescription includes specific food items and quantities to meet the nutritional needs.
The document provides an overview of the current status of nutrition labelling and claims in Malaysia. Key points include:
- Nutrition labelling is mandatory for over 50 categories of foods in Malaysia since 2005.
- Claims must be accompanied by full nutrition labelling.
- Permitted claims include nutrient content, comparative and function claims. Disease risk reduction claims are prohibited.
- There are criteria for labelling of mandatory and optional nutrients as well as conditions for certain nutrition claims.
- Approval of new claims involves review by expert committees and the Director General of Health.
This document contains spotters (short case studies) on various foods including cereals, pulses, nuts, and dairy. It provides details on the nutritional composition, properties, and recommended consumption of each food. For example, the wheat spotter discusses that it is higher in protein than rice but lower quality, and whole wheat is preferable to refined wheat. The milk spotter notes its protein and energy content per 100ml. The document aims to inform medical students and health professionals about essential nutrition information through concise spotters on individual food items.
enhancing the functionality of milk by dietary manipulationSharishKumar2
This document summarizes strategies to enhance the functionality of milk through dietary modification. It discusses:
1) What are functional foods and considerations for them, including that they are foods derived from natural ingredients that have a particular function when consumed as part of the daily diet.
2) Ways to increase certain nutrients and compounds in milk like conjugated linoleic acid, omega-3 fatty acids, selenium, and docosahexaenoic acid through feeding practices such as increasing intake of their precursors from pasture, plants, or supplements.
3) Research showing how dietary changes like adding oils, herbal extracts, or fish oil to cow feed can boost nutrients like CLA, omega-3s, and D
Pulses are an important source of protein in vegetarian diets, providing essential amino acids that cereals and grains lack. Proteins are needed for growth, tissue synthesis, digestive juices, hormones, and more. Pulses also provide energy and fiber. While protein quality varies, pulses have a net protein utilization of around 65 compared to egg protein. A table lists the nutrient contents of various pulses commonly consumed in India, such as Bengal gram, black gram, cowpea, and soybean. Pulses additionally contain vitamins and folic acid.
This document provides an overview of papaya, including its classification, origins, main active ingredients, health benefits, mechanisms of action, nutrition facts, and potential side effects. Papaya contains several proteolytic enzymes such as papain and chymopapain that aid in protein digestion. It also has antioxidant and anti-inflammatory properties that may help reduce risks of certain cancers and lower blood pressure and cholesterol. Potential side effects include skin irritation, increased bleeding risk when taken with blood thinners, and unsafe consumption during pregnancy or breastfeeding.
Dr Q's YeastMycin is a supplement formulated to support gastrointestinal health and microbial balance through a blend of ingredients including oregano extract, sodium caprylate, ginger, turmeric, and olive leaf extract. These ingredients have been studied and have mechanisms to support antioxidant activity, healthy gastrointestinal flora, digestion, and immune function. The comprehensive formula is designed to maintain gastrointestinal tract health and microflora balance while supporting antioxidant systems and tissue health.
AHS13 Jeff Leighton — The Role of Omega 3 Oils in the Treatment of Chronic In...Ancestral Health Society
Inflammation is associated with virtually all chronic, progressive diseases such as heart disease, vascular disease, asthma, IBS, autoimmune diseases, rheumatoid arthritis, osteoarthritis and even chronic neurological diseases such as Alzheimer’s disease. The signals that induce inflammation are multifactorial. High dose omega 3 has the potential to be as or more effective than pharmaceutical therapies. We will report on a series of omega 3 studies that compared dose response, dose timing, (e.g. once a day or twice a day), and food intake (with or without) in four separate cohorts.
This document provides information about Tegreen 97, a green tea extract dietary supplement produced by Pharmanex. It contains 97% polyphenols, the highest level in the industry, equivalent to drinking 7 cups of green tea. Research shows green tea's polyphenols, especially EGCg, protect cells from damage by acting as antioxidants, preventing lipid peroxidation, and inducing programmed cell death in abnormal cells. Tegreen 97 supports general well-being and cellular health to help reduce risks of serious diseases like cancer.
During the webinar, Sophie covers in depth the new Restore and Maintain treatment protocol, including the unique benefits of a combination of strength, concentration and dose for providing the fastest acting, most effective, therapeutic omega-3 intervention strategy to support your clients’ health. She details how to use the Pharmepa range to provide truly personalised nutrition support to meet your clients’ individual omega-3 needs. After explaining the benefits of the protocol as a whole, Sophie covers the key conditions Pharmepa has been designed to support and the dosing guidelines for clients with these concerns.
This document summarizes key nutrients that provide calories - carbohydrates, fats, and proteins. It describes the sources and functions of carbohydrates including sugars, starches, and fiber. It also discusses the different types of fats including saturated, unsaturated, and trans fats. Finally, it covers the sources and functions of protein as well as complete and incomplete protein sources and dietary recommendations.
Role of Phytoestrogens in Breast CancerNeha Dhiman
because of the side effects caused by the synthetic drugs and therapies, it is better to rely on natural products. natural products has lot of benefits and risk is less.
This document discusses nutraceuticals and probiotics. It defines nutraceuticals as foods that provide medical benefits for preventing and treating diseases. Examples mentioned include foods high in fatty acids, polyphenols, carotenoids, and dietary fiber. Probiotics are live microorganisms that benefit digestive health. Prebiotics are non-digestible foods that promote probiotic growth. The document outlines the history of probiotics and their roles in supporting immunity, digestion, and chronic illness prevention. Common probiotic sources like yogurt and kefir are noted. Research on using probiotics for conditions like obesity, osteoporosis, and cancer is also summarized.
Black cumin oil contains the potent antioxidant thymoquinone. Studies show thymoquinone has anti-inflammatory and analgesic properties, and helps stimulate bile production and fat metabolism in the liver. Black cumin is also high in essential fatty acids and vitamins that are beneficial for brain function, blood pressure, and immune defenses. Research has found black cumin oil to have anti-oxidant, anti-inflammatory, and potential anti-cancer effects. Black cumin nourishes the body, aids digestion, and promotes skin and immune health.
Dr. Robert Rutledge authored a paper on how bile acid depletion through gastrointestinal bypass decreases HbA1c, serum glucose, and improves insulin sensitivity. The paper reviews literature showing that bile acids are signaling molecules that regulate glucose, lipid, and energy metabolism. Studies demonstrate that decreasing bile acid pools through procedures like duodenal bypass results in lower blood glucose and better insulin sensitivity. Manipulating bile acid levels may help treat diabetes.
This document provides information on the management of dyslipidemia. It discusses non-pharmacological treatment including lifestyle changes like exercise and diet. Pharmacological treatments for dyslipidemia are also outlined, including statins, fibrates, bile acid resins, nicotinic acid derivatives, cholesterol absorption inhibitors, and fish oil supplements. The mechanisms of action, dosages, adverse effects and patient counseling points are described for each drug class.
This document provides information on hyperlipidemia and dyslipidemia, including their causes, risk factors, diagnostic testing, and treatment options. It notes that disorders of lipoprotein metabolism that increase LDL-C and total cholesterol while decreasing HDL-C raise cardiovascular disease risk. Genetic and environmental factors both contribute to primary dyslipidemia. Lifestyle changes and lipid-lowering medications, particularly statins, are used to treat abnormal lipid levels and reduce disease risk. The main drug classes for treatment include statins, fibrates, bile acid sequestrants, cholesterol absorption inhibitors, and niacin.
This webinar is designed to teach practitioners about how to use and recommend the Igennus cardiovascular health treatment protocol for maximum results in your clients. We will cover the evidence for the use of the nutrients within the protocol and provide the recommended dosing regime for a range of cardiovascular health concerns.
This document discusses various appetite stimulants, digestants, and carminatives. It describes how appetite is influenced by several factors in the hypothalamus and gut-brain pathways. Common appetite stimulants mentioned include lemon pickles, bitter orange peel, and soups containing aromatic oils. Some medications can increase appetite but also have side effects. The document also discusses various digestive enzymes and bile acids that may aid digestion, though evidence for their efficacy is limited. Finally, it outlines several common carminative herbs and spices that can relieve gas and bloating.
Nutrition of patients undergoing dialysisManiz Joshi
This document discusses nutritional assessment and dietary recommendations for dialysis patients. It outlines several methods for assessing nutritional status, including physical exams, body composition measurements, functional tests, and biochemical markers like serum albumin and prealbumin. Optimal intake levels are provided for proteins, sodium, fluids, potassium, phosphorus, and various vitamins. Maintaining adequate nutrition through diet and supplements is important for dialysis patients given losses during treatment and high risk of malnutrition.
Ilex paraguariensis, commonly known as yerba mate, contains compounds such as caffeine, theobromine, saponins, and phenolic acids that have been shown to help with weight management and metabolic syndrome. The document discusses the chemical composition of mate, potential product indications including aiding in weight loss and improving cardiovascular health and lipid profiles, selection of marker compounds to standardize extracts, and methods for analyzing key compounds. In conclusion, mate is suggested to have potential as a product for weight loss and management of obesity-related diseases due to its diverse phytochemistry and multiple pharmacological activities.
Hyperlipidemia is an abnormally elevated level of lipids in the blood and is a major risk factor for coronary heart disease. It can be caused by lifestyle factors like poor diet and lack of exercise or genetic defects. Treatment involves therapeutic lifestyle changes as well as drug therapy to lower cholesterol levels and reduce the risk of cardiovascular events and death. Statins are the first-line treatment as they significantly reduce low-density lipoproteins, while other drugs like niacin, fibrates, and cholesterol absorption inhibitors are also used either alone or in combination with statins.
Cholesterol lowering with plant stanol ester containing Benecol foods and foo...Benecol
Presentation is for healthcare professionals only. Benecol foods and food supplements with plant stanol ester are proven to lower blood cholesterol. Presentation about the scientific background of plant stanol ester and reducing blood cholesterol with it.
Hyperlipidemia is an abnormally elevated level of lipids in the blood and is a major risk factor for coronary heart disease. It can be caused by lifestyle factors like poor diet and lack of exercise or genetic defects. Treatment involves therapeutic lifestyle changes as well as drug therapy to lower cholesterol levels and reduce the risk of cardiovascular events and death. Statins are the first-line treatment as they significantly reduce low-density lipoproteins, while other drugs like niacin, fibrates, and bile acid sequestrants are also used either alone or in combination with statins.
This document summarizes recent therapeutic approaches for dyslipidemia. It discusses lifestyle changes like smoking cessation, weight loss, improved diet, and increased physical activity. It also discusses pharmacological management including ATP III guidelines, novel therapies that block lipoprotein output or increase clearance like PCSK9 inhibitors. Therapies to raise anti-atherogenic lipoproteins by promoting ApoA1 production or cholesterol efflux are also covered, as well as therapies slowing HDL removal and dual PPAR agonists. Surgical modalities like partial ileal bypass and liver transplantation are mentioned for severe dyslipidemia cases.
Lipid metabolism and hypolipedemic drugsUrmila Aswar
This document discusses lipid metabolism and hypolipidemic drugs. It defines different types of lipids including triglycerides, cholesterol, and lipoproteins. It describes the normal metabolism of lipids and how elevated LDL and triglycerides can lead to conditions like atherosclerosis. The document then summarizes several classes of drugs used to treat hyperlipidemia including statins, bile acid sequestrants, cholesterol absorption inhibitors, and fibrates. It provides examples of drugs in each class and their effects on lipid levels as well as common adverse effects.
This document discusses the impacts of diet on serum lipid profiles. It begins by describing normal cholesterol and triglyceride metabolism in the body. It then discusses how dietary components like saturated fats, trans fats, fiber, and cholesterol affect serum lipids. Lifestyle modifications like following a low-fat, plant-based diet pattern and engaging in regular physical activity are recommended to lower LDL cholesterol and blood pressure. Several clinical trials are summarized that show how replacing saturated fats with unsaturated fats from plants lowers cardiovascular disease risk.
Management of atherosclerosis and hyperlipidemia.pdfHemanhuelCTankxes
The agent most likely causing the bleeding symptoms is gemfibrozil.
Gemfibrozil is a fibrate medication used to treat high triglyceride levels and works by activating PPAR receptors. It can interact with and potentiate the effects of warfarin, increasing the risk of bleeding. Atorvastatin and cholestyramine are unlikely to directly cause bleeding. While niacin can increase bleeding risk by affecting prostaglandin levels, it is less likely than gemfibrozil in this case given the patient is on an anticoagulant already.
Fibrates - class, effects, side effects, drugs interactions, main indications...OlgaGoryacheva4
My student Niraj Maheshwari had presented this topic in our 22nd Student Scientific Society Conference in the department of Propaedeutic of Internal Diseases No.2
Antihyperlipidimic drug therapy-current and noval approaches.pptxMohammedObaidMohiudd
This document outlines a seminar presentation on current and novel approaches for treating dyslipidemia. It discusses the relationship between different lipids like LDL, HDL, and triglycerides and cardiovascular disease risk. It then summarizes the current drug therapies for dyslipidemia which lower LDL cholesterol through statins, bile acid sequestrants, ezetimibe, and nicotinic acid. Novel drug targets and approaches being researched are also highlighted, including monoclonal antibodies against PCSK9 to further lower LDL, as well as strategies to increase HDL through CETP inhibitors, vaccines, and HDL mimetics. The conclusion emphasizes the need for new biomarkers and trials to monitor progression of atherosclerosis with these novel therapies.
Omega-3 Polyunsaturated Fatty Acids and Metabolic Syndrome Josh Nooner
This document reviews metabolic syndrome and the role of omega-3 fatty acids. It summarizes early studies showing omega-3's positive effects on cardiovascular health. Two supporting studies and one main study are discussed. Supporting Study 1 found fish oil reversed metabolic abnormalities in rats. Supporting Study 2 found omega-3 supplements improved cardiovascular risk factors in humans with metabolic syndrome. The main study found omega-3's improved endothelial function and arterial stiffness in metabolic syndrome patients, with anti-inflammatory effects. Overall, increasing omega-3 intake may benefit reversing metabolic syndrome. Future research on optimal ratios and long-term effects is recommended.
Presentation - Omega-3 PUFAs and Metabolic SyndromeJosh Nooner
1) Two supporting studies found that omega-3 fatty acid supplements significantly improved multiple metabolic abnormalities and markers of cardiovascular risk in subjects with metabolic syndrome.
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#61I 5th International Conference on Rice Bran Oil 24th - 25th May 2018, Hanoi, Vietnam
1. Cardiometabolic Health Benefits of
Rice Bran Oil
Dr. Sankar Devarajan, MD (Bio), Ph.D, FAHA, FADA
Associate Professor
Nutrition and Dietetics Program
Department of Human Sciences
University of Arkansas at Pine Bluff, USA
Former Regional Head, WHO
2. •Rice bran oil (RBO) presents several advantages over other
cooking oils due to the presence of many bioactive antioxidant
components which are responsible for its oxidative stability and
health benefits.
•The crude RBO encompasses a rich unsaponifiable fraction
(~5%), which consists of sterols (43%), triterpene alcohols
(28%), 4-methyl-sterols (10%) and other less polar components.
•The phytosterols include β-sitosterol, campesterol, stigmasterol,
squalene and γ-oryzanol. γ-Oryzanol is often recognized as the
most active component of RBO.
•RBO is also a rich source of vitamin E (both tocopherols and
tocotrienols) as well as contains variable quantities of
tocotrienols, especially β- and γ-tocotrienols.
•γ-Oryzanol has similar functions as vitamin E.
Bioactive Components of Rice bran Oil
3. Significance of RBO in Human Health
•RBO is gaining popularity because of its better cooking
characteristics, prolonged shelf life and well-balanced fatty acid
composition as well as the presence of bioactive substances.
•RBO is commonly used in many Asian cultures, where it is
regarded as “premium edible oil”. In Japan, RBO is commonly
known as a “heart oil”, whereas in Western countries, it has
attained the status of a “healthy food” (CAC 2003). It is also
now becoming popular in the USA and other parts of the world
because of its relatively low price and many health benefits.
•RBO has been shown to have the potential to lower cholesterol,
blood pressure and blood glucose and can help to reduce
inflammation and symptoms of metabolic syndrome as well.
4. •RBO has been shown to be effective in the prevention and
management of cardiovascular disease (CVD) risk factors if
consumed as part of a healthy diet. It may also help to boost
the immune system and prevent diabetes, cardiovascular
diseases, cancer and premature ageing.
•Studies have reported that RBO diet relieves the menopausal
symptoms, increases the cognitive function and may lower
the incidence of allergic reactions.
5. RBO-Perspectives in Cardiometabolic Diseases
Management
Anti-hyperlipidaemic and Hypocholesterolaemic Effect of RBO
•Studies have shown that the intake of RBO reduced the plasma
TC, TG and LDL-C and increased the HDL-C levels in rodents,
rabbits, non-human primates and humans.
•RBO have been shown to have beneficial effects on lipid
metabolism in terms of their antioxidant, hypolipidaemic and
anti-atherogenic properties.
•The bioactive phytosterols, γ- oryzanol and tocotrienols in RBO
are responsible for its anti-hyperlipidaemic properties. The
phytosterols, in particular the ss-sitosterol and 4-
desmethylsterols and not the 4,4′-dimethylsterols in RBO,
have been shown to reduce the plasma TC and LDL-C
levels.
6. • It has been studied that the supplementation of high-cholesterol
diet with γ-oryzanol showed an increased bile flow and total
bile acid excretion with simultaneous 20% decrease in
cholesterol absorption which suggest that the bioactive γ-
oryzanol and some other components in the unsaponifiable
fraction of RBO such as tocotrienols and tocopherols can
increase the faecal excretion of bile acids and neutral sterols.
• Supplementation of RBO with γ-oryzanol appeared to be
strongly associated with alleviating the cardiovascular disease
risk factors in animal models, especially when fed a high-fat
diet.
• Use of physically refined RBO may be attributed to decreased
cholesterol absorption and not to the hepatic cholesterol
synthesis. It has been suggested that a reduction in fatty streak
formation, the early signs of atherosclerosis with physically
refined RBO, may be due to its non-triglyceride fraction.
7. •γ-Oryzanol rich RBO significantly reduced plasma lipid
hydroperoxides and triglycerides in high-fat diet fed hamsters.
These results indicated that γ-oryzanol might have potentiated
the lowering of plasma LDL and VLDL levels and may also
help to raise the HDL cholesterol.
•The cholesterol-lowering efficacy of RBO is much superior that
is apparently judged based on its fatty acid composition.
•γ-Oryzanol is considered as the possible fundamental
component of RBO due to its anti-atherosclerotic action. It
inhibits the intestinal absorption of cholesterol, increases the
bile flow and accelerates the excretion of cholesterol in the
faeces.
•Data from the animal studies confirmed the anti-
hyperlipidaemic properties of γ-oryzanol and its overall impact
to lower the CVD risk.
8. RBO in Clinical Trials on Humans
•Earlier studies have reported the anti-hyperlipidaemic properties
of RBO in healthy young Japanese women. This study showed
that the daily use of 60 g of a blend of RBO and safflower oil
(70:30) was more effective in lowering the plasma TC levels;
even only after 7 days of treatment!
•Data from various studies in which RBO was given for 4-14
weeks period indicated that the RBO at a dose level up to 50
g/day was effective in reducing the TC, LDL-C, TG and
apolipoprotein levels with a simultaneous increase in HDL-C.
•Ishihara and his colleagues evaluated the impact of γ-oryzanol
supplementation on 40 women with postmenopausal syndrome.
Treatment with 300 mg of γ-oryzanol/day for 4-8 weeks showed
a significant decrease in plasma TC, LDL-C and TG levels with
a simultaneous increase in HDL-C.
9. •It was observed that the patients who used RBO showed 16%
and 25% decrease in plasma TC and 32% and 35% reduction in
plasma TG after 15 and 30 days of treatment, respectively,
•Double-blind 12-wk long clinical trial on hypercholesterolaemic
human subjects, who were given a supplement of tocotrienol-
rich fraction that was obtained from specially processed RBO,
together with a standard National Cholesterol Education
Program (NCEP) Step-1 diet, indicated a significant decrease in
plasma TC and LDL-C.
•It appears that the RBO and its bioactive components may be
able to safely improve the plasma lipid profile in
hypercholesterolaemic patients.
•Various clinical trials have clearly indicated that the
consumption of RBO-rich diets can significantly improve the
levels of HDL-C in hypercholesterolaemic human subjects.
10. •A recent study has reported the effects of RBO versus statins on
blood glucose, HbA1C and serum lipid profiles in patients with
type 2 diabetes. The RBO group was given a low-calorie diet,
and the patients consumed 30 g/day RBO. They also used RBO
as the main cooking oil for 6 months. The patients in
atorvastatin group received a low-calorie diet together with 40
mg/day of atorvastatin drug for 6 months. The diabetic and
moderately hyperlipidaemic patients showed significant increase
in the fasting and postprandial blood glucose, HbA1C and liver
transaminase levels on atorvastatin, whereas there was a
reduction in all these parameters in RBO group. This study
concluded that the use of RBO together with dietary
modifications may be effective in reduce the incidence of
cardiovascular diseases.
11. Anti-diabetic Effect of RBO
•Tocotrienol-rich fraction of RBO has been shown to act as an
antioxidant to effectively decrease the HbA1C.
•Tocotrienols in RBO are considered to lower blood TC
concentrations by inhibiting the HMG-CoA reductase activity.
•Tocotrienols have cardioprotective properties by improving the
postischaemic ventricular functions and reducing the
myocardial infarction. The bioactive components and
antioxidants present in RBO as well as its oleic acid and
conjugated linoleic acid contents may help to boost the
metabolic rate, regulate the blood glucose and lipid profile,
reduce inflammation, lose weight and may control obesity.
•γ-Oryzanol can regulate the secretion of insulin and blood
glucose levels by normalizing the liver enzyme activities and
therefore may lower the risk of hyperglycaemia.
12. •Pigmented rice berry bran oil may have beneficial effects on
diabetes by reducing the oxidative stress.
•RBO is effective in ameliorating the neuropathic pain in
diabetic patients.
•RBO has been shown to inhibit hyperinsulinemia
•ADA recommends that in order to improve the
hyperlipidaemia and to prevent heart-related diseases, the
diabetic patients should consume those vegetable oils, which
contain high amounts of oleic acid.
•RBO, because of its optimal fatty acid composition and
bioactive components, which have high absorption capacity in
the GI tract, can not only inhibit the intestinal absorption of
cholesterol and block the synthesis of cholesterol analogues,
and increase the excretion of its metabolites from the body and
thus may reduce the incidence of cardiovascular diseases.
13. Effects of RBO on Oxidative Stress
•RBO and its high antioxidant potential can better help to
prevent cellular lipid and protein oxidation.
•It has been concluded that rice bran extracts including RBO
have great nutraceutical potential in the prevention of
mitochondrial dysfunctions and may attenuate the oxidative
stress in neurodegenerative diseases.
•Tocotrienols exhibit stronger antioxidant activity which is
attributed to their high capacity to donate phenolic hydrogen
to various free radicals.
•RBO diets can improve the antioxygenic potential and may
protect against oxidative stress.
•Bioactive components of RBO may exert synergistic effect in
combating the reactive oxygen species (ROS) and may
therefore help in the prevention of cellular oxidative damage.
14. Health Benefits of RBO Blends
Effect RBO and Sunflower oil blend in Type 2 Diabetes
Sankar Devarajan et al (Under Publication in Biomedicine and Pharmacotherapy)
0
20
40
60
80
100
120
140
Baseline (0 day) Sun-Rice oil
Intervention (30th day)
Withdrawal of Sun-Rice
oil (60th Day)
FastingBloodglucose(mg/dl)
BLOOD GLUCOSE (Fasting)
21. Using a blend of unrefined sesame oil and physically refined
rice bran oil (20:80) as cooking oil in patients with type 2
diabetes mellitus
• Lowers blood glucose (FBG 14.36%; PPG 21.9% and
HbA1C 10%)
• Lowers TC (20%), LDL-C (31%) and TG (13%)
• Increases HDL-C by (12%)
• Shows an additive effect with Glibenclamide for highly
significant reduction of blood glucose (FBG 30%; PPG 35%
and HbA1C 22%).
Sankar Devarajan et al. 2016, Am J Med, 129; 731-739
24. Using a blend of unrefined sesame oil and physically refined rice
bran oil (20:80) as cooking oil in mild-to-moderate hypertensive
patients
• Lowers blood pressure (SBP 12.8%; DBP 13.5% and MAP
12.9%)
• Lowers total cholesterol (18.3%), low-density lipoprotein
cholesterol (27.5%), triglycerides (12.6%) and non-high-
density lipoprotein cholesterol (25.4%)
• Increases high-density lipoprotein cholesterol (11%)
• Shows an additive effect with nifedipine for highly significant
reduction of blood pressure (SBP 23.8%; DBP 23.6% and MAP
23.2%).
Sankar Devarajan et al. 2016, J Clin Lipidol, 10; 339-349
25. •Dietary strategies are considered as the first line of defense in
the prevention and management of diabetes, cardiovascular
diseases. RBO with its excellent fatty acid composition and
bioactive antioxidants has demonstrated beneficial effects to
improve the plasma lipid profile.
•Consumption of RBO has been shown to have a direct
relationship with its antihypertensive, antidiabetic and lipid-
lowering efficacies.
•As evidenced from several observational and clinical studies,
it is well documented that the RBO has an imperative role in
the prevention, management and control of cardiometabolic
diseases, and therefore RBO would certainly be a valuable
dietary addition as functional food.
Conclusion
26. On going Research with Rice Bran components
Screening of Rice Bran components for Chymase Inhibitory
Indications: Selectivity of the Functional Potentiality Food
compounds for Depressor Effect
USDA-Capacity Building Grant 2017
Project Director-Dr. Sankar Devarajan ($ 500,000)
Acknowledgement
Adani Wilmar Limited, Gujarat, India
Fukuoka University Chikushi Hospital, Japan