2. Mitral
regurgitatio
n
▪Backflow of blood through a
defective heart valve
▪.Any one or more of the five
functional components of the mitral
valve apparatus-
▪Leaflets, Annulus,Chordae tendineae,
Papillary muscles,Subjacent
myocardium
7. Pathophysiolo
gy
▪Regurgitation into the LA produces LA
dilatation
▪But little increase in left atrial pressure if the
regurgitation is chronic- as the regurgitant
flow is accommodated by thelarge left atrium
▪ Acute mitral regurgitation - normal
compliance of the left atrium does not allow
much dilatation- left atrial pressure rises.