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4.2 BODY DEFENCE
CIKGU JELLY
BODY DEFENCE MECHANISM
CIKGU JELLY
Non-specific body defence mechanism
Prevent pathogen from entering the body
1. Skin
 Made of a tough layer and is difficult to be penetrated by microorganism
 Microorganism can only get into the body if there is a wound or if the skin is
injured
 Sweat and sebum secreted by the skin contain chemicals that can kill
microorganism
BODY DEFENCE MECHANISM
CIKGU JELLY
Non-specific body defence mechanism
Prevent pathogen from entering the body
2. Mucous membrane
 Membrane that lines the digestive tract and respiratory tract
 Microorganism that enter the respiratory tract are filtered by nasal hairs and
trapped by mucous lining the nasal cavity
 Earwax, tear and vaginal secretions also function as an antiseptic that kill
microorganism
BODY DEFENCE MECHANISM
CIKGU JELLY
Non-specific body defence mechanism
Fight pathogen through phagocytosis
 Pathogens that successfully get past the first line of defence enter
the bloodstream and face the second line of defence
 White blood cells engulf and digest the pathogens using enzymes through
phagocytosis
phagocytosisPHAGOCYTOSIS
pathogen
BODY DEFENCE MECHANISM
CIKGU JELLY
Specific body defence mechanism
Fight pathogen by producing antibodies
 Pathogens that succeed in passing through the second line of
defence will face the third line of defence
 Immunity is the ability of the body system to resist pathogens before it is
infected
BODY IMMUNE SYSTEM
 It is involves the production of antibodies when pathogen enter the body
 Antibody is a protein produced by white blood cells into the
bloodstreams in response to antigen
 Antigen is a foreign substance that comes from outside body and induces
the production of antibodies
IMPORTANCE OF IMMUNISATION
 Immunisation is an effort to
stimulate the body defence
against infections by injecting
vaccines
 Vaccines-Contains antigens
obtained from a part or the whole
structure of weakened or dead
virus or bacterium
 Antigens stimulate the body’s
immune system, forming
immunity against certain
infections
CIKGU JELLY
2020 VACCINATION SCHEDULE IN MALAYSIA
•Vaccines given at government health facilities:
•Bacillus Calmette–Guérin (BCG), vaccine that gives protection against
tuberculosis
•DTaP is the combination of diphtheria(D), tetanus(T) and acellular pertussis(aP)
•DT is a booster dose which protects against diphtheria (D) and tetanus (T)
•Hib is Haemophilus Influenza type B
•MMR is the combination of Measles(M), Mumps(M) and Rubella(R)
•MR vaccine provides protection against Measles (M) and Rubella (R). MR Dose 2
at 7 years old, until year 2022
•JE is vaccine against Japanese Encephalitis. This vaccine is only provided in
Sarawak
•HPV is Human Papillomavirus. This vaccine is provided only for girls aged 13
years. Dose 2 is given 6 months after dose 1
CIKGU JELLY
 SOURCE: MINISTRY OF HEALTH MALAYSIA
PASSIVE IMMUNITY
CIKGU JELLY
Concentration of antibody
in the blood(%)
Immunity level
Time(week)
Passive natural immunity Passive artificial immunity
Concentration of antibody in
the blood(%)
Time(week)
First antiserum
injection
Second antiserum
injection
Immunity level
The body gains antibody from external sources
 Obtained when a baby receives
antibody from breast milk or from the
mother’s blood that flows across the
placenta
 Temporary and short-lived, last for the
first few months after the birth of the
baby
 Obtained when antiserum injected into
patient’s body
 Antiserum fights against pathogens without
interrupting the patient’s immune system
 Antiserum is a clear liquid in the blood that
contain antibodies to prevent diseases
 Fast and temporary
ACTIVE IMMUNITY
CIKGU JELLY
Concentration of antibody
in the blood(%)
Immunity level
Time(week)
Active natural immunity Active artificial immunity
Concentration of antibody in
the blood(%)
Time(week)
Immunity level
The body produces its own antibodies when
stimulated by antigens
First vaccine
injection
Second vaccine
injection
During the second time infection, the
antibody produced exceeds the immunity
level and immunity is achieved
 Occur when a person recovers from an
infection
 Immunity last long after the infections
 Occur when a vaccine that contains a
dead or weakened pathogen injected
into the body and the immune system
respond by producing antibodies
 Immunity last long after the infections
CAUSES THAT WEAKEN THE IMMUNE SYSTEM
CIKGU JELLY
 Exposure to polluted air
 Exposure to pesticides
 Stress
 Excessive intake of sugar
PRACTICES THAT STRENGH THE IMMUNE SYSTEM
CIKGU JELLY
 Get enough sleep and rest
 Exercise and inhaling
fresh air
 Not smoking and no exposure to
cigarettes smoke
 Doing periodic health
examination

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4.2 BODY DEFENSE

  • 2. BODY DEFENCE MECHANISM CIKGU JELLY Non-specific body defence mechanism Prevent pathogen from entering the body 1. Skin  Made of a tough layer and is difficult to be penetrated by microorganism  Microorganism can only get into the body if there is a wound or if the skin is injured  Sweat and sebum secreted by the skin contain chemicals that can kill microorganism
  • 3. BODY DEFENCE MECHANISM CIKGU JELLY Non-specific body defence mechanism Prevent pathogen from entering the body 2. Mucous membrane  Membrane that lines the digestive tract and respiratory tract  Microorganism that enter the respiratory tract are filtered by nasal hairs and trapped by mucous lining the nasal cavity  Earwax, tear and vaginal secretions also function as an antiseptic that kill microorganism
  • 4. BODY DEFENCE MECHANISM CIKGU JELLY Non-specific body defence mechanism Fight pathogen through phagocytosis  Pathogens that successfully get past the first line of defence enter the bloodstream and face the second line of defence  White blood cells engulf and digest the pathogens using enzymes through phagocytosis phagocytosisPHAGOCYTOSIS pathogen
  • 5. BODY DEFENCE MECHANISM CIKGU JELLY Specific body defence mechanism Fight pathogen by producing antibodies  Pathogens that succeed in passing through the second line of defence will face the third line of defence  Immunity is the ability of the body system to resist pathogens before it is infected BODY IMMUNE SYSTEM  It is involves the production of antibodies when pathogen enter the body  Antibody is a protein produced by white blood cells into the bloodstreams in response to antigen  Antigen is a foreign substance that comes from outside body and induces the production of antibodies
  • 6. IMPORTANCE OF IMMUNISATION  Immunisation is an effort to stimulate the body defence against infections by injecting vaccines  Vaccines-Contains antigens obtained from a part or the whole structure of weakened or dead virus or bacterium  Antigens stimulate the body’s immune system, forming immunity against certain infections CIKGU JELLY
  • 7. 2020 VACCINATION SCHEDULE IN MALAYSIA •Vaccines given at government health facilities: •Bacillus Calmette–Guérin (BCG), vaccine that gives protection against tuberculosis •DTaP is the combination of diphtheria(D), tetanus(T) and acellular pertussis(aP) •DT is a booster dose which protects against diphtheria (D) and tetanus (T) •Hib is Haemophilus Influenza type B •MMR is the combination of Measles(M), Mumps(M) and Rubella(R) •MR vaccine provides protection against Measles (M) and Rubella (R). MR Dose 2 at 7 years old, until year 2022 •JE is vaccine against Japanese Encephalitis. This vaccine is only provided in Sarawak •HPV is Human Papillomavirus. This vaccine is provided only for girls aged 13 years. Dose 2 is given 6 months after dose 1 CIKGU JELLY  SOURCE: MINISTRY OF HEALTH MALAYSIA
  • 8. PASSIVE IMMUNITY CIKGU JELLY Concentration of antibody in the blood(%) Immunity level Time(week) Passive natural immunity Passive artificial immunity Concentration of antibody in the blood(%) Time(week) First antiserum injection Second antiserum injection Immunity level The body gains antibody from external sources  Obtained when a baby receives antibody from breast milk or from the mother’s blood that flows across the placenta  Temporary and short-lived, last for the first few months after the birth of the baby  Obtained when antiserum injected into patient’s body  Antiserum fights against pathogens without interrupting the patient’s immune system  Antiserum is a clear liquid in the blood that contain antibodies to prevent diseases  Fast and temporary
  • 9. ACTIVE IMMUNITY CIKGU JELLY Concentration of antibody in the blood(%) Immunity level Time(week) Active natural immunity Active artificial immunity Concentration of antibody in the blood(%) Time(week) Immunity level The body produces its own antibodies when stimulated by antigens First vaccine injection Second vaccine injection During the second time infection, the antibody produced exceeds the immunity level and immunity is achieved  Occur when a person recovers from an infection  Immunity last long after the infections  Occur when a vaccine that contains a dead or weakened pathogen injected into the body and the immune system respond by producing antibodies  Immunity last long after the infections
  • 10. CAUSES THAT WEAKEN THE IMMUNE SYSTEM CIKGU JELLY  Exposure to polluted air  Exposure to pesticides  Stress  Excessive intake of sugar
  • 11. PRACTICES THAT STRENGH THE IMMUNE SYSTEM CIKGU JELLY  Get enough sleep and rest  Exercise and inhaling fresh air  Not smoking and no exposure to cigarettes smoke  Doing periodic health examination