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BEACH 2019 – FS Taccone
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BEACH 2019 – FS Taccone
ECMO Principles and
Different Modes
Fabio Silvio TACCONE, MD, PhD
Dpt of Intensive Care
Brussels, Belgium
BEACH 2019 – FS Taccone
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BEACH 2019 – FS Taccone
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WHAT IS ECMO ?
V-V ECMO V-A ECMO
BEACH 2019 – FS Taccone
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Extra-corporeal life support
(ECLS)
Cardiac ECLS Respiratory ECLS
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RESPIRATORY ECLS
VV-ECMO functions as an artificial
lung working in addition to the
patient's own failing lungs
• To maintain gas exchanges
• To allow protective ventilation
• To allow “lung rest”
• To allow “lung recovery”
• To gain time for LTx
BEACH 2019 – FS Taccone
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RESPIRATORY ECLS
<
CO
SvO2
VO2
BEACH 2019 – FS Taccone
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RESPIRATORY ECLS
BEACH 2019 – FS Taccone
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RESPIRATORY ECLS
BEACH 2019 – FS Taccone
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RESPIRATORY ECLS
VCO2
BEACH 2019 – FS Taccone
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RESPIRATORY ECLS
BEACH 2019 – FS Taccone
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CARDIAC ECLS
ECMO FLOW = CARDIAC OUTPUT
VOLUME x PUMP (CANNULA)
LIMB
ISCHEMIA
LUNG
INJURY
HARLEQUIN
SYNDROME
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 The best perfusion flow
 Off-load the left ventricle
 Almost no pulmonary edema
 Very invasive (chest opening)
 Bleeding
 Infection
 Vascular injury (Aortic dissection)
 Significant risk of thrombosis
CARDIAC ECLS
VA-ECMO
Central Cannulation
BEACH 2019 – FS Taccone
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CARDIAC ECLS
BEACH 2019 – FS Taccone
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T7T8
T9
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T11T12L1L2L3
CARDIAC ECLS
BEACH 2019 – FS Taccone
T1T2T3T4T5T6
T7T8
T9
T10
T11T12L1L2L3
CARDIAC ECLS
ECMO FLOW = CARDIAC OUTPUT
VOLUME x PUMP (CANNULA)
LIMB
ISCHEMIA
LUNG
INJURY
HARLEQUIN
SYNDROME
INCREASED
AFTERLOAD
BEACH 2019 – FS Taccone
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CARDIAC ECLS
BEACH 2019 – FS Taccone
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T7T8
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CARDIAC ECLS
BEACH 2019 – FS Taccone
T1T2T3T4T5T6
T7T8
T9
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CARDIAC ECLS
BEACH 2019 – FS Taccone
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ECLS
BEACH 2019 – FS Taccone
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ECLS AND OTHER EXTRACORPOREAL THERAPIES
RRT MV
LIVER
SUPPORT
HEMOPERFUSION
BEACH 2019 – FS Taccone
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T11T12L1L2L3
Extra-corporeal life support
(ECLS)
Cardiac ECLS Respiratory ECLS
 VA-ECMO
 V-PA ECMO
 ECPR
 VV-ECMO
 V-PA ECMO
 AV-ECCO2R
 VV-ECCO2R
Veno-artero-venous
ECLS
HYBRIDCOMBINED
BEACH 2019 – FS Taccone
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3. ecmo different modes and principles va vv #beach2019 (taccone)

  • 1. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 BEACH 2019 – FS Taccone ECMO Principles and Different Modes Fabio Silvio TACCONE, MD, PhD Dpt of Intensive Care Brussels, Belgium
  • 2. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3
  • 3. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 WHAT IS ECMO ? V-V ECMO V-A ECMO
  • 4. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 Extra-corporeal life support (ECLS) Cardiac ECLS Respiratory ECLS
  • 5. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS VV-ECMO functions as an artificial lung working in addition to the patient's own failing lungs • To maintain gas exchanges • To allow protective ventilation • To allow “lung rest” • To allow “lung recovery” • To gain time for LTx
  • 6. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS < CO SvO2 VO2
  • 7. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS
  • 8. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS
  • 9. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS VCO2
  • 10. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 RESPIRATORY ECLS
  • 11. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS ECMO FLOW = CARDIAC OUTPUT VOLUME x PUMP (CANNULA) LIMB ISCHEMIA LUNG INJURY HARLEQUIN SYNDROME
  • 12. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3  The best perfusion flow  Off-load the left ventricle  Almost no pulmonary edema  Very invasive (chest opening)  Bleeding  Infection  Vascular injury (Aortic dissection)  Significant risk of thrombosis CARDIAC ECLS VA-ECMO Central Cannulation
  • 13. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS
  • 14. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS
  • 15. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS ECMO FLOW = CARDIAC OUTPUT VOLUME x PUMP (CANNULA) LIMB ISCHEMIA LUNG INJURY HARLEQUIN SYNDROME INCREASED AFTERLOAD
  • 16. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS
  • 17. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS
  • 18. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 CARDIAC ECLS
  • 19. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 ECLS
  • 20. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 ECLS AND OTHER EXTRACORPOREAL THERAPIES RRT MV LIVER SUPPORT HEMOPERFUSION
  • 21. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3 Extra-corporeal life support (ECLS) Cardiac ECLS Respiratory ECLS  VA-ECMO  V-PA ECMO  ECPR  VV-ECMO  V-PA ECMO  AV-ECCO2R  VV-ECCO2R Veno-artero-venous ECLS HYBRIDCOMBINED
  • 22. BEACH 2019 – FS Taccone T1T2T3T4T5T6 T7T8 T9 T10 T11T12L1L2L3

Editor's Notes

  1. HOW IT WORKS ?
  2. 47% vs 63% (22/90 not ECMO – mortality 18%!!!) – no difference on good outcome
  3. HOW IT WORKS ?
  4. 47% vs 63% (22/90 not ECMO – mortality 18%!!!) – no difference on good outcome
  5. CARDIAC INJURY = afterload < increase BP / aortic regurgitation
  6. Central cannulation when oxygenation is not needed anymore – two circuits with cannulation of heart chamber (usually apex but also atria) excellent means of unloading the heart and maintaining the blood flow via pulmonary vasculature
  7. Without the oxygenator – it would be considered as a temporary VAD Femoral requires often a reperfusion catheter to avoid limb ischemia But also axillary or carotid
  8. Without the oxygenator – it would be considered as a temporary VAD Femoral requires often a reperfusion catheter to avoid limb ischemia But also axillary or carotid
  9. CARDIAC INJURY = afterload < increase BP / aortic regurgitation