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Ageing and Mobility: ILC Global 
Alliance Symposium 
Wednesday 29th October 2014 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Welcome 
Louise Plouffe 
ILC-Brazil 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Welcome from the Local 
Government Association 
Cllr Marianne Overton MBE 
Elected Leader of the LGA Independent Group and 
Vice Chair of the LGA, Lincolnshire County Council and 
North Kesteven District Council 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Welcome from Alliance Boots 
Andrew Bonser 
Director of Public Policy 
Alliance Boots 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Sarcopenia: A forgotten cause of 
mobility problems in old age 
Rosy Pereyra 
President 
ILC-Dominican Republic 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Sarcopenia: A Forgotten Cause of Mobility 
Problems in Old Age 
Rosy Pereyra, M.D. 
President ILC-DR 
ILC-GA Symposium.- London. England October 29th, 2014
7 
Sarcopenia a Forgotten Cause of Mobility Problems in Old Age 
Introduction and Definition 
Syndrome characterized by a progressive and generalized diminution of 
muscle mass and strength with the risk of adverse effects such as 
physical disability, poor quality of life and death. 
 It is perhaps the most serious threat to health and longevity and it is 
believed to play a role in the pathogenesis of fragility and the functional 
problems that accompany ageing.
The Classical Definition of Sarcopenia is 
Based in Muscle Mass 
-1 
DE 
Severe 
sarcopenia 
-2 
DE 
Risk of Normal 
sarcopenia 
Media 
• Lean mass of 
extremities 
(kg)/estature (m)2 
• Total lean mass 
(kg)/body weight (kg) 
Body muscle mass 
Baumgartner RN, et al. Am J Epidemiol. 1998;147:755-763. 
Janssen I, et al. J Am Geriatr Soc. 2002;50:889-896. 
DistribuciĂłn en adultos jĂłvenes
9 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Prevalence 
 It is estimated that approximately 5-13% of people between 60-70 years 
are affected by sarcopenia. 
 There is an estimated loss of 0.5-1% per year after the age of 25 and this 
accelerates after the age of 60, doubling in each decade specially in 
inactive people.
Three measures of muscular function and one of muscle mass in men and women 
10 
Muscle strength and potency diminish 
with ageing 
Strength of knee extension 
Manual pressure 
Varones Mujeres Varones Mujeres 
20 40 60 80 100 20 40 60 80 100 
Muscle strength Calf muscle 
Varones Mujeres Varones Mujeres 
Lauretani F, et al. J Appl Physiol. 2003;95:1851-1860. 
(N/dm) 
Years of age 
1000 
750 
500 
250 
0 
0 
(kg) 
Years of age 
80 
60 
40 
0 
0 
(watios) 
Years of age 
400 
320 
240 
160 
80 
0 
0 60 100 
(cm2) 
Years of age 
0 
20 
100 
80 
60 
40 
20 
20 40 80 20 40 60 80 100
11 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Phisiopathological Changes 
 Ageing is associated to changes not only in muscular mass but also in 
muscle compositiĂłn its properties and contractility.
Changes in muscle fibers affect 
Strength and Potency 
ReinervatiĂłn 
Lang T, et al. Osteoporosis Int. 2010;21:543-559. 
Qualitative 
changes in 
muscle 
Type 1 fibers Type II fibers Motorneurone DenervatiĂłn 
Ageing Sarcopenia 
• Increase in 
type I fibers 
• Diminution in 
type II fibers 
Disminutionl in 
ttransversal area
Senil miosteatosis 
Miosteatosis 
• Increase in 
intermuscular and 
intramuscular fat 
Transversal cut of the thigh through resonance 
Transversal cut of the thigh through tomography
Intramuscular fat increase even with a 
stable body weight 
Muscle Intermuscular adipose tissue Succutaneous adipose tissue 
6 
2 
-2 
* Significativamente diferente respecto al 
momento basal,p < 0,01 
Delmonico MJ, et al. Am J Clin Nutr. 2009;90:1579-1585. 
Five years longitudinal study 
Varones Mujeres 
Evaluation respect to 
basal moment (%) 
8 
4 
0 
-4 
-6 
-10 
-12 
* 
* 
* 
*
15 
Sarcopenia. A forgotten Cause of Mobility Problems in Old Age 
Causal Mechanisms 
 Loss of ability of satellite cells to self multiply 
 Loss of ability of muscle to respond to anabolic stimuli such as that of 
Insulin, growth hormone and amino acids. 
 Insufficient protein in the diet. 
 Lack of frequent exercise.
16 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Effects of Sarcopenia 
 Diminution of physical function 
 Increased disability 
 Increased dependency 
 Mobility problems 
 Increase in health costs
Sarcopenia Diminishes Function 
and Increases disability 
0 2 4 6 8 10 
Walk 400 
meters 
Climb 10 steps 
Lift 4,5 kg 
Walk 2,5 
meters 
Get up 5 times 
from a chair 
Hability to take care of 
themselves 
Make their own 
meals 
Activities of daily 
living 
Janssen I, et al. J Am Geriatr Soc. 2002;50:889-896.
Sarcopenia has an Elevated 
Health Cost 
Men Women 
Normal Moderate 
Sarcopenia 
Severe 
sarcopenia 
Normal Moderate 
Sarcopenia 
Severe 
sarcopenia 
Prevalence 36% 53% 11% 69% 22% 9% 
Relative risk 
of disability, 
% 
1.00 3.48 4.60 1.00 1.46 3.15 
Cost in US 
thousand 
millions 
- 7.18 3.63 - 2.7 4.96 
The direct health cost attributed to sarcopenia in The US in the year 2000 was 
18.500 million dollars (nearly 1,5% of the total health cost of that year). 
Janssen I, et al. J Am Geriatr Soc. 2004;52:80-85.
19 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old age 
Diagnosis 
Should be stablished when two out of three criteria are met: 
1. That there is a reduction in muscle mass. 
2. That there is a reduction in muscle strength and/or low exercise 
tolerance.
20 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Diagnosis 
 Muscle mass is 2 standard deviations below a population of reference. 
 Diminution of the walking speed below 0.8 mts/sec in a 4 meters 
walking trial. 
 CAT scan, MRI, anthropometry and the valuation of creatinine excretion 
are also used.
21 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Treatment 
 Since sarcopenia is due to multiple factors, its prevention and treatment 
require an integrated approach that should include: 
 Diet 
 Hormonal replacement therapy 
 Nutritional supplements including Vitamin D and 
 Exercise
Protein Synthesis and Muscle Mass 
• Proteins in the diet stimulate protein 
synthesis in older people 
• An increase in the intake of protein 
> 0,8 g/kg/day 
- Increase the anabolism of proteins in 
muscles 
- Can help to avoid the senile decrease in 
muscle mass 
Paddon-Jones D, et al. Am J Clin Nutr. 2008;87:1562S-1566S.
Oral Nutritional Supplements plus 
Resistance Exercises Increase Muscle 
Strength 
Design 
• n = 63 women and 37 men, 
87,1 Âą 0,6 years (interval: 72-98) 
• The strength was measured as a 
maximal repetition of extensor 
muscles of the hip and knees 
after a 10 weeks intervention. 
RESULTS 
• In fragile old people you get 
better results when you associate 
exercise with oral nutritional 
supplements. 
Exercise Control 
Experimental Group 
Fiatarone M, et al. N Engl J Med. 1994;330:1769-1775. 
Variation in strength (%) 
500 
400 
300 
200 
100 
0 
-100 
-200 
Exercise plus 
supplements 
Supplements 
** 
*
24 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Hormonal Replacement Therapy 
 Growth hormone 
 Mechano growth factor and insulin like growth factor 
 Testosterone
25 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Exercise
26 
Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age 
Finally 
 Ageing produces a diminution of muscle mass, strength, and muscular 
function. 
 Sarcopenia is defined mainly by the degree of diminution of muscle 
mass. 
 Sarcopenia is due to a complex interaction between many factors 
among those, nutrition. 
 The diminution of muscle mass in sarcopenia, increases the risk of 
fragility, mobility problems, disability and has an elevated health cost. 
 It can be avoided by having a good nutrition and exercising during your 
life time. These are probably the more efficient public health 
interventions for this condition.
27 
Sarcopenia. A forgotten Cause of Mobility 
Problems in Old Age 
!!!!!!!!!! Thank you and let’s start!!!!!!!!!!!
Contacts to the presenter: 
Rosy Pereyra, M.D. 
President ILC-DR 
(809) 449-9551 
rosy.pereyra@gmail.com
Are we living longer and healthier? 
Exploring gender differences in health 
expectancy among older Singaporeans 
Susana Concordo Harding 
Director 
ILC-Singapore 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
For more information about this presentation, please 
contact Susana Concordo Harding at 
susanaharding@tsaofoundation.org 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Prevalence and risks factors for falls, 
and the impact on mobility in later life: 
The Cape Town study 
Dr Sebastiana Kalula 
Director 
ILC-South Africa 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Ageing and mobility: 
Impact of falls – 
the Cape Town study 
Sebastiana Kalula 
ILC South Africa 
University of Cape Town
Falls are a major cause of morbidity and 
mortality, and contributor to impaired functioning 
and mobility in older people
Long lie (>1 hour) 
• Pneumonia 
• Dehydration 
• Pressure sores 
Social 
• Social withdrawal 
• Institutionalization 
Impact of a fall 
Functional 
• Immobility 
• Deconditioning 
• Decreased righting reflex 
Psychological 
• Fear of falls 
• Loss of confidence 
• Depression 
• Increased dependency 
Physical injuries 
• Bruises 
• Head injury 
• Fractures 
Source: Grimm and Mion 2011; Lord et al., 2001, Donald and Bulpitt 1999, Tinetti and Williams 1997
Impact of hip fractures 
• 2 % of falls result in hip fracture 
• 25 % die within 6 months 
• 60 % have restricted mobility 
• Management and social costs 
are high 
Sources: Chu et al., 2006; O’Loughlin et al., 1993; 
Tinetti et al., 1988.
Although prevalence and incidence rates of 
falls are well established in high income 
countries, little is known on falls in low to 
middle income countries, particularly in 
sub-Saharan Africa 
South Africa is listed as a middle income 
country, but has a large poor population
Africa region studies 
Information on falls in older persons in Africa is 
sparse 
• Single study in Rwanda (Ntagungira, 2005) 
focused on older persons who had fallen; 
recurrent fallers constituted 23.3 % 
• Single retrospective study in Nigeria (Bekibele 
and Gureje, 2010) established a fall prevalence 
rate of 23 % 
• Until now, no information in South Africa
Cape Town study on falls 
Surveyed 837 community-dwelling older persons with a 
12-month follow-up 
Sample size 837 aged ≥ 65 years 
• Gugulethu n=231 (black Africans) 
• Plumstead n=145 (whites) 
• Wynberg n=264 (coloureds (mixed ancestry)) 
Follow up sample n=632 
Kalula, 2012
Prevalence of falls: Cape Town study 
• At baseline: 26.4 % 
Recurrent falls: 11 % 
• At follow-up: 22 % 
Recurrent falls: 6.3% 
• Incidence rate: 367 per 1000 person years 
– 236 per 1000 person years for men 
– 405.7 per 1000 person years for women 
• Recurrent falls more common in women: 82.5 %
Fall prevalence by ethnic group: 
Cape Town study 
Whites 
n 
140 
% 
42.9 
Coloureds 392 34.4 
Black Africans 283 6.4
Risk factors for falls: Cape Town study 
Independent risk factors for a fall were mainly self-reported 
conditions: 
• Medical conditions (poor mobility, poor 
vision, poor urine control, depression, 
Parkinson’s disease) 
• Self-rated poor health status 
• Medication use (antidepressants, anti-inflammatory 
drugs)
Ethnic differences in risk factors 
Occupation category 
(%) 
Reference 
Black African 
n = 283 
Whites 
n = 140 
OR (95% CI) 
Unskilled 221 (78.1) 12 (8.6) 1 
Skilled 58 (20.5) 94 (67.1) 30 (15–58)* 
Managerial 4 (1.4) 34 (24.3) 157 (47–513)* 
Health compared to a 
year ago (%) ‒ Worse 15 (5.3) 9 (6.4) 2.17 (0.85 – 5.58) 
Mobility ‒ With 
difficulty 47 (16.6) 20 (14.3) 0.84 (0.47 – 1.48) 
Total number in 
household (median, 
IQR)) 
7 (5-8.5) 2 (1-3) 0.32 (0.26 – 0.38)* 
*P value = <0.001
Characteristic 
Reference 
Black 
African 
n = 283 
White 
n = 140 OR (95% CI) 
Age in years (median, (IQR)) 74 (69-78) 76.5 (70-81) 1.04 (1.01–1.08)# 
Comorbidities (median, (IQR)) 3 (2-4) 4 (2-5) 1.39 (1.18 – 1.52)* 
Number of drugs (median, (IQR)) 3 (1-4) 4.5 (2-7) 1.36 (1.25 – 1.49)* 
Self-reported depression (%) Yes 23 (8.1) 21 (15.0) 2.00 (1.06 – 3.75)* 
Geriatric Depression Scale score 1 (1-6) 2 (1-3) 0.89 (0.83 – 0.97)$ 
Use of psycholeptics (%) Yes 1 (0.4) 13 (9.3) 28.87 (3.74–223.0)* 
Self-rated health (%) Poor 228 (80.6) 25 (17.9) 0.05 (0.03 – 0.09)* 
p value: * < 0.001, # =0.006, $= 0 005
Occupation category 
(%) 
Reference 
Black African 
n = 283 
White 
n = 140 OR (95% CI) 
SES Index score 6 (5 – 6) 8 (8 – 8) 5.23 (3.94 – 6.94)* 
Cognitive score 8 (4 – 12) 2 (0 – 5.7) 0.83 (0.79 – 0.87)* 
Hand grip strength (kg) 14 (10.5–19) 16 (11 – 22) 1.04 (1.01 – 1.06)* 
One leg stand eyes 
3 (1 – 7) 13 (6 – 26) 1.14 (1.11 – 1.17)* 
open (seconds) 
One leg stand eyes shut 
(seconds) 
1 (0.0 – 4.0) 3 (2.0 – 6) 1.13 (1.07 – 1.19)* 
Up & Go test (seconds) 20 (18 – 23) 12 (10 – 16) 0.89 (0.86 – 0.92)* 
Chair stands (seconds) 20 (19 – 22) 12. (10 – 15) 0.79 (0.73 – 0.82)* 
SES= Socio-economic Status index; score of 8 items in household; * p value: < 0.001
Falls and medical help: Cape Town study 
• At baseline, 72 per cent reported injury resulting 
from a fall and 42 per cent sought medical help 
for the injury 
• At follow-up, 70 per cent reported injury and 38 
per cent sought medical help
Consequences of a fall: Cape Town study 
Baseline Follow-up 
% % 
• Injuries 
- soft tissue 69.7 68.1 
- fractures 14.4 5.7 
• Fear of falls 53.9 60.1 
• Not fully recovered 41.7 39.4
Environmental hazards for falls: Cape Town study 
Surveyed 837 older persons 
Outdoors N (%) Indoors N (%) 
Stairs/steps 293 (35) Slippery floor 221 (26.4) 
Road (uneven surface, 
86 (10.3) Mats/loose carpet 189 (22.6) 
potholes, stones, road works, 
slippery) 
Ground (stones, sand, uneven) 53 ( 6.3) Children/pets/toys 54 (6.5) 
Garden (furniture, toys, plants, 
hose, washing line) 
21 (2.5) Stairs/steps 52 (6.2) 
Veranda (slippery, uneven, holes) 20 (2.4 Furniture 37 (4.4) 
Pavement (people, uneven, 
rubble, banana peels, cracks) 
19 (2.3) Getting out of a bath 31 (3.7)
Findings and questions 
• Finding of marked ethnic differences in fall 
prevalence was unexpected and raises questions 
• Speculated that life-time manual labour preserves 
gait and balance in the relatively deprived black 
African sub-sample, hence a low fall rate 
• Far lower fall rate in black Africans despite high 
poverty levels and more environmental hazards in 
their residential area
Recommendations 
• Design and implement falls intervention 
programmes to sustain mobility 
• History taking, rather than tests, is a more 
reliable tool for clinicians to identify those at risk 
of a fall who could benefit from intervention 
• Educate and train health professionals in 
screening for falls, and management of risk 
factors and consequences of a fall
Thank you
MOBILAGE 
Dr Didier Halimi 
ILC-France 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
MOBILAGE 
D. HALIMI (ILC-France) on behalf of 
BROCA Hospital, CEREMH, RATP and ILC-France 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
52
MOBILAGE: MOBILITY FOR ALL ! 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
53
MOBILAGE 
The situation 
• Outdoor mobility of older people is 
– a matter of freedom , preservation of autonomy, psychological & 
social wellbeing 
– essential for prevention of dependency 
• Loss of mobility has negative consequences 
– depressive symptoms after cessation of driving (Marottoli, 1997) 
• Driving remains the favourite mode of transportation 
– for > 50% of people 75 + (Sofres 1990-2000) 
– driving ability should to be assessed 
• potentially impacted by physical, sensory or cognitive deficits 
• to ensure secure driving as long as possible 
– Alternatives should be proposed if ability to drive is impaired 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
The project 
• To evaluate outdoor mobility of pre-frail and frail elderly and their 
caregivers through workshops and training focusing on mobility 
• Objectives 
• Identify the risks of decreased mobility1 
• Analyze participants’ mobility1 
• Propose tailored training 
• Walking in public area , 
• Driving, cycling, public transportation1 
• Inform on alternative outdoor mobility aids 
• support patients and their families in their implementation2,3 
• This pilot project will include 
– 100 pre-frail and frail subjects 75 or older 
– re-evaluated after 6 months. 
1: BROCA Hospital; 2: CEREMH ; 3: RATP 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
Why should I participate? 
• I am embarrassed by certain movements 
• I reduced the frequency of my outings 
• I am concerned about my mobility 
• I find it hard to get around 
• I do not feel confident while driving 
• I am curious to test new devices 
• I do not feel confident in public transport and I use 
them less 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
Who will benefit ? 
• Patients, relatives and professionals in gerontology will 
directly or indirectly benefit from this program 
• Communication of results will help educate the public about 
the issue of elder’s mobility 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
In practice 
First step 
Mobility evaluation and needs assessment of pre-frail and frail 
persons or their caregivers after medical evaluation and sensory 
testing ( BROCA Hospital) 
Second step 
if the person is eager to learn more about the potential benefits of 
the MOBILAGE program 
• Awareness and testing session 
• Theoretical training: traffic laws and road signalling 
• Practical training: driving assessment with a driving 
instructor (and a psychomotor therapist if needed), bicycles, 
tricycles, adapted scooters, use of public transportation … 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
Where are we? 
• 72 pre-frail and frail people or their caregivers have 
accepted the mobility screening (first step) 
• 16 have attended the mobility workshops ( second 
step ) to get 
– additionnal information on new mobility aids and to test 
them 
– And/or driving support 
• Limitations 
– Fear of taking the plunge 
– Availability for the workshops 
– Budget and technical maintenance for the new mobility 
aids 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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MOBILAGE 
The Partners 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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CEntre of REsources & Innovation Mobility & 
Handicap 
Non profit organisation 
National Centre of Expertise for technical aids for 
Mobility by the CNSA 
Paris Public Transportation Network 
BROCA Hospital
Draisine (draisienne) a walking aid that allows you to move 
while sitting upright 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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Awareness and discovery of 
new mobility solutions
Adapted Scooters 
For people who walk and want solution to increase their 
mobility perimeter 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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Awareness and discovery of 
new mobility solutions
Different adapted cycles: bicycles, 
tricycles, and electrical cycles 
ILC Gobal Alliance Mobility Symposium 
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Awareness and discovery of 
new mobility solutions
Balance learning to ... 
... Control the bike, or 
simply regain confidence. 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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Individual or small group sessions to learn 
safe city traffic 
ILC Gobal Alliance Mobility Symposium 
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Theoretical training: 
Refresh regulation and signalling 
ILC Gobal Alliance Mobility Symposium 
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Driving school: driving sessions with 
practical advice to regain confidence. 
ILC Gobal Alliance Mobility Symposium 
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Support to use Public 
Transportation 
Albertine takes the bus! 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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CONCLUSION 
• Outdoor mobility is key for the wellbeing and 
the preservation of autonomy 
• MOBILAGE is a valuable experiment, stressing 
– The importance of a correct evaluation of the 
mobility and needs of the pre-frail and frail 
persons and their caregivers 
– The need for some support services to increase 
the adherence of the persons to the proposed 
solutions 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
69
This presentation has been made possible thanks to: 
• Broca Hospital: Marie-Laure SEUX, Laure CAILLARD, Mélanie 
CORNUET 
• CEREMH: Claude DUMAS, Antoine VERNIER, Elisabeth JOSEPH 
• RATP: Jean-Pierre TEXIER 
70 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14
ILC-France 
• Françoise Forette, MD 
• Marie-Anne Brieu, MD 
• Philippe Guillet, MD 
• Jean-Claude Salord, MD 
• Didier Halimi, MD 
ILC Gobal Alliance Mobility Symposium 
London 10.29.14 
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Short Comfort Break 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Maintaining Older People’s 
Mobility: What Do We Need? 
Kunio Mizuta 
President 
ILC-Japan 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Maintaining Older 
People’s Mobility: 
What Do We Need? 
To Promote Older People’s Independence 
“Aging and Mobility,” ILC- Global Alliance Conference 
October 29, 2014 
London 
Kunio MIZUTA 
President, ILC-Japan 
74
1. Demographic Trends in Japan 
Population Aging: Estimates & Projections 
75 
% of the elderly: 7.9% (1975) ⇒ 25.1% (2013) ⇒ 30.3% (2025) 
# of the old-old: 2.8mil.(1975) ⇒ 15.5mil.(2013) ⇒ 21.8mil. (2025) 
9.0 15.6 
6.0 2.8 
13.0 
75.8 86.2 
16.3 
79.0 
21.8 
14.8 
70.8 
23.9 
13.8 
50.0 
27.2 18.5 16.4 13.2 9.4 
140 
120 
100 
80 
60 
40 
20 
0 
1975 2000 2013 2025 2050 
75- 
65-74 
15-64 
0-14 
Total: 111.9 
% of 65+: 7.9% 
million 
people 
126.9 
17.4% 
97.1 
38.8% 
120.7 
30.3% 
127.3 
25.1% 
Cabinet Office (2014). Annual Report on the Aging Society
2. Significance of Mobility among 
Older People, Research Supporting 
“LTC Prevention” Programs 
Reasons for Needing Care 
Many people start needing care due to locomotor 
disabilities 
Cerebro-vascular 
disease 
(Stroke) 
Joint 
disorder, 
fracture, 
fall 
Demen-tia 
Age-related 
frailty 
Cardiac 
(heart) 
disease 
Other, 
unknown 
Total 21.5 21.1 15.3 13.7 3.9 24.5 
Male 32.9 11.3 10.9 10.5 4.5 29.9 
Female 15.9 25.8 17.5 15.3 3.7 21.8 
76 
Reasons for needing care by sex (%) 
Ministry of Health, Labour and Welfare (2012). Comprehensive Survey of Living Conditions.
Older People’s Walking & IADL 
Walking speed is an important health indicator. 
Programs to increase motor function can be effective. 
◆ First sign of disability: Loss of ability to walk. Then 
problems with toileting and eating. 
◆ A longitudinal study (5 year follow-up study) shows that 
the groups with slower walking speed are at higher risk for 
IADL decline (slowest group: 23%, fastest group: 5%). 
◆ An exercise intervention study for older people proves that 
a program to increase motor function improves physical 
function (walking speed, MCS) and mental health (WHO-5). 
Suzuki, T. (2012). The Basics on a Hyper-Aged Society (pp.42-43). Kodansha Gendai Shinsho. 
Ohbuchi, S., et al. (2010). Research on comprehensive evaluation and analyses regarding long-term care prevention. In T. 
Suzuki et al. (eds), Report on a Comprehensive Research Project Regarding Long-Term Care Prevention (p.33). Japan Public 
Health Association. 
77
Lower frequency of going out is an independent risk 
factor for problems w/ walking and cognitive function 
◆ A longitudinal study shows: 
Frequency of going out: 3 groups 
“1+/day” “1/every few days” “<1/week” 
(Odds ratios at the 2-yr. follow-up study) 
Problem w/ walking 
1.00 1.78 4.02 
Problem w/ cognitive function 
1.00 1.58 3.49 
78 
Frequency of Going Out & 
Older People’s Health 
Fujita, K., et al. (2006). Frequency of going outdoors as a good predictor for incident disability of physical 
function as well as disability recovery in community-dwelling older adults in rural Japan. Journal of 
Epidemiology, 16 (1), 261-270.
◆A longitudinal study examined what effects the 
total hours of productive activities have on older 
people’s health 
(3 year follow-up study) 
Significant differences in ADL (going out, standing 
up from a chair/bed, going to the toilet, etc.) and 
cognitive impairments (SPMSQ score) 
Shibata, H., Sugihara, Y., & Sugisawa, H. (2012). Social contribution by middle-aged and older Japanese: Its contributing 
factors and effects on physical and emotional well-being. Analyses of 2 representative panel data. Applied Gerontology, 
6, 21-38. 
79 
Hours of Activities & 
Levels of ADL Cognitive 
Productive acImtivpitaieirsm caenn tpsrevent ADL 
and cognitive impairments
Summary of Existing Studies 
1. A significant number of people start 
needing care due to locomotor disabilities. 
2. Speed of walking is an important health 
indicator among older people. 
3. Lower frequency of going out is a risk 
factor for problems with walking and 
cognitive function. 
4. Programs to increase motor function can 
be effective. 
5. Productive activities can prevent ADL and 
cognitive impairments. 
80
3. Comprehensive Community Care & 
Long-Term Care Prevention 
Comprehensive Community Care 
(providing integrated community support, including housing, health care, LTC, 
preventive care and assistance w/ daily living, so that people can stay in a familiar 
environment) 
◆Within the frame of CCC, municipalities are urged and 
supported to make efforts to prevent frailty by maintaining 
and restoring older people's 
motor function through 
evidence-based way of 
exercise. 
◆Active participation by 
residents, especially older 
people and community 
as a whole is essential. 
81 
Long-term care prevention service, Sakai city, Fukui 
prefecture
4. Other Measures to Promote 
Locomotor Health & LTC Prevention 
Basic Health Check List for Those Over 65years Old is 
distributed to about 50% of the elderly population by 
local municipalities, and about 30% of older people fill it 
out. 
82 
Health Checkups for LTC 
Prevention 
Questionnaires 
1 daily life 
Do you normally travel by bus or train by yourself? 
Do you go out and buy daily necessities by yourself? 
Do you manage your own deposits and savings at the bank? 
Do you often go out to visit your friends? 
Do you consult with your family or friends about their problems? 
2 physical ability 
Are you able to go upstairs without holding rail or wall? 
Are you able to stand up from the chair without any aids? 
Are you able to keep walking for about 15 minutes? 
Do you worry about falling down? 
… 
… ©AMDA International Medical Information Center 2008
Prevention of 
“Locomotive Syndrome” 
83 
“Health Japan 21” Campaign 
(Ministry of Health, Labour and Welfare) 
“The Locomotive Challenge! Council” 
(The Japanese Orthopaedic Association + private enterprises) 
Bones 
Muscles 
Joints 
Bone strength 
Fall/fracture 
Sarcopenia 
Burden on 
joint/inflammation 
Mobility 
Limited 
activities/social 
participation 
Needing care
Measures to Build a Better Environment to Improve Mobility 
Barrier-Free Act (Enacted in 2000, revised in 2006) 
Ensuring independent living for older 
people & those w/ disabilities 
◆ Promoting barrier-free design: Streets, 
parks, buildings, public transportation, etc. 
◆ Focused efforts to promote barrier-free 
design: Around stations and areas 
frequently used by older people and those 
w/ disabilities 
84
Mobility Support Project 
85 
Ubiquitous Tanba Sasayama 
Reading QR codes + 
Providing WiFi positional 
info 
Internet 
(WiFi service) 
QR Code 
System configuration & available 
contents 
Routing assistance 
Info on 
facilities 
Info on 
restrooms 
Bus timetables 
Providing contents 
(content server) 
Walking space network data
Conclusion 
◆ Maintaining and improving older 
people’s mobility are tools to promote 
their social participation. Programs to 
maintain and improve mobility cannot be 
effective without older people’s positive 
attitude toward a society. 
◆ That is, we can pave the way for a 
hyper-aged society based on the concept 
of Productive Aging. 
86
Loss of mobility, loss of Autonomy, 
loss of quality of life 
Lia Daichman 
President 
ILC-Argentina 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
-ARGENTINA 
“LOSS OF MOBILITY, 
LOSS OF AUTONOMY, 
LOSS OF QUALITY OF LIFE” 
LIA SUSANA DAICHMAN MD 
CYNTHIA MARIÑANSKY MD 
MAG. SOFÍA APTEKMAN SW 
ROSANA SILBERMAN SW 
London, Oct. 2014
INTRODUCTION 
-ARGENTINA 
Life-space scales have been developed 
to assess movement of individuals 
from home to beyond town or region 
in contrast with classic measures of mobility 
that do not take into account 
the interaction with the living environment.
DEMOGRAPHY 
-Argentinean total population: 
40.117.096 persons 
corresponding 5.725.838 to people 
60 years and older 
- People over 65 years of age 
represent 10.2% 
14.3% are 60 years old and over. 
- Middle life expectancy at birth is 
around 75.5 years, 
72.5% for males and 80% for 
females. 
•The proportion of seniors in Argentina is the 
third [1] 
highest in the Latin American Region 
after Uruguay and Cuba. 
-ARGENTINA
GROUP PROFILE: ANALYSIS 
Gender: 82% females 
N = 50 
 Average age: 77.1 years, (77.5 (F) and 75.4(M) 
 Education: 54% high school; 7% university; 
Income: 80% believed “sufficient” 
 Health: 76% perceived themselves to be in a good health 
 Marital status: 44% widows; 36% married; 6% divorced; 
14% single (exceed the rate of the City of BsAs) 
-ARGENTINA 
 Living arrangements: 66% with other people; 44% living alone.
RESULTS 
-ARGENTINA 
 Cognitive functioning: 84% normal; 16% had some difficulties. 
 Depressive symptoms: 70% showed no depressive symptoms; 
30 % presented depressive symptoms. 
 Physical limitations: 58 % had no difficulty with the Chair Test; 
20 % had some difficulties; 
22% could not perform the test at all. 
 ADL: 84% had no difficulty; 16% require assistance 
 Space Life: 52% were above 87 points; 32% between 56 and 
87 points and 16% below the 56 point line 
which is considered risk (highest 120 points)
-ARGENTINA 
HIGHLIGHTS 
Differed according to previous personalities and coping mechanisms 
through their life cycles. 
Nearly 70% expressed that their lives would be highly impaired in the case 
they should have to remain at home: 
- “I would commit suicide because I love my home and activities” 
- “I cannot even think about it” 
- “I really never thought about it” 
- “I would lose my freedom, I would become a slave” 
- “I would be depressed, I wouldn´t like to live like that” 
- “I would lose my job, the one I depend on.” 
-“I would adapt myself, I would look for company and help” – 
-“I expect it won’t happen, it would be very hard”
-ARGENTINA
-ARGENTINA 
DISCUSSION 
- A high percentage of our population expressed that a situation like 
this would influence on their emotional state by means of 
depression, sadness, anguish, anxiety about the future and 
helplessness… 
-The vast majority of people admitted that they would need help. 
(It seems that FAMILY would be the first answer). 
- Nevertheless, a fair number of people, who would accept help, do not 
mention family as their first resource. More than that, they explicit 
would feel pretty bad about having to rely on their children or 
grandchildren for informal care. 
- Older sons and daughters, more than often take care of their own 
- grandchildren and when they have to look after their older parents, 
even if they privilege the little ones, they find themselves in a difficult 
position which they cannot escape and have little choice… .
RECOMMENDATIONS 
-ARGENTINA 
•Inform and prepare older person, their families and the 
community in general about what to do and how to deal with 
gradual or sudden loss of autonomy’ situations. 
•Work with Focus groups or special courses for older persons 
addressing risk factors related to this age group and generate 
alternative projects that extend and strengthen existing and new 
networks of support. 
•Create specialized public and private centers for advice and 
support to older persons and their families to be used as 
required. 
•Promote programs and awareness workshops on 
intergenerational solidarity to facilitate inclusion of older adults 
in need of care
RECOMMENDATIONS 
-ARGENTINA 
• Stimulate more public and private policies to build or improve and 
adapt homes for older people for present and future needs. 
• Sensitize the population about the importance of home safety to 
 
prevent accidents. 
• Promote within the community the importance of physical activity, 
health care and active ageing to prevent deterioration and disability. 
• Encourage individual, intergenerational and community social, 
exchange, including older persons, to promote the consolidation 
of support networks at a useful level when necessary. 
• Work individually or in groups, in terms of medical and social 
services, to avoid, prevent, and support sensory deprivations as 
well as all types of MOBILITY’s loss.
Thank you very much from 
Buenos Aires!.. 
-ARGENTINA 
liadaichman@fibertel.com.ar
Local and national initiatives to support 
active ageing and improve quality of 
long-term care in the Czech Republic 
Dr Iva HolmerovĂĄ 
President 
ILC-Czech Republic 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Local and national initiatives to 
support active ageing and improve 
quality of long-term care in the 
Czech Republic 
Iva HolmerovĂĄ, Petr Wija 
ILC-Czech Republic
Healthy Life Expectancy (Wija 2012) 
2011 Ĺženy muĹži 
hly 63,6 62,2 
le 80,7 74,7 
% hly 78,8% 83,3% 
rozdĂ­l muĹži Ĺženy: 6 let (LE), 1,4 let (HLY)
P. Wija, 2013
Future need of long-term care will depend on 
(EC 2013): 
• 
– Numbers of persons 80+ 
• 
– Health status of population, healthy life expectancy, 
chronic diseases and multimorbidity 
– Ability to live in home environment despite 
disability
Enabling model of geriatric care 
(P.Millard, 1994) 
Acute care – dg and treatment 
Rehabilitation 
Long-term care 
Functional 
improvement
Disabling model of geriatric care 
(P.Millard, 1994) 
Dg and th 
RHB 
Long-term care 
Underestimation 
of geriatric care 
needs – fixation 
of disability
BEDEKR 
Guide on Active Ageing 
or 
How to find the way in the landscape of active 
ageing and long-term care 
Holmerová I., Starostová O., Vepřková R., Wija P.
BEDEKR 
 Support of active ageing on the community level 
 Participation and communication with local authorities 
 Independent living 
 Environment and mobility
BEDEKR 
 Intergenerational activities 
 Voluntary work 
 Education 
 ICT literacy and internet 
 Social activities 
 Physical activity and sports
BEDEKR 
Mobility: 
- Important aspect of quality of life 
- Necessary for self-maintenance 
Individual level (rehabilitation, support, 
aids) 
Community level – no barriers, transport 
Societal level - enabling environment
CELLO – ILC – CZ 
• Thanks to: 
• Dana Hradcová – GOS Project and CELLO 
Coordinator 
• Marcela Janečková – FRAM Project 
• Olga Starostová – FRAM Project 
• Radka Vepřková – FRAM Project 
• Hana Vaňková – IGA and GOS Project 
• Petr Veleta – GOS Project
Panel Response 
Marieke van der Waal 
Director, ILC-Netherlands 
Jayant Umranikar 
ILC-India 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance
Ageing and Mobility: ILC Global 
Alliance Symposium 
Wednesday 29th October 2014 
This event is kindly supported by Alliance Boots and hosted by the LGA 
#ilcglobalalliance

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Ageing and Mobility: Exploring the Impact of Sarcopenia and Falls

  • 1. Ageing and Mobility: ILC Global Alliance Symposium Wednesday 29th October 2014 This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 2. Welcome Louise Plouffe ILC-Brazil This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 3. Welcome from the Local Government Association Cllr Marianne Overton MBE Elected Leader of the LGA Independent Group and Vice Chair of the LGA, Lincolnshire County Council and North Kesteven District Council This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 4. Welcome from Alliance Boots Andrew Bonser Director of Public Policy Alliance Boots This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 5. Sarcopenia: A forgotten cause of mobility problems in old age Rosy Pereyra President ILC-Dominican Republic This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 6. Sarcopenia: A Forgotten Cause of Mobility Problems in Old Age Rosy Pereyra, M.D. President ILC-DR ILC-GA Symposium.- London. England October 29th, 2014
  • 7. 7 Sarcopenia a Forgotten Cause of Mobility Problems in Old Age Introduction and Definition Syndrome characterized by a progressive and generalized diminution of muscle mass and strength with the risk of adverse effects such as physical disability, poor quality of life and death.  It is perhaps the most serious threat to health and longevity and it is believed to play a role in the pathogenesis of fragility and the functional problems that accompany ageing.
  • 8. The Classical Definition of Sarcopenia is Based in Muscle Mass -1 DE Severe sarcopenia -2 DE Risk of Normal sarcopenia Media • Lean mass of extremities (kg)/estature (m)2 • Total lean mass (kg)/body weight (kg) Body muscle mass Baumgartner RN, et al. Am J Epidemiol. 1998;147:755-763. Janssen I, et al. J Am Geriatr Soc. 2002;50:889-896. DistribuciĂłn en adultos jĂłvenes
  • 9. 9 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Prevalence  It is estimated that approximately 5-13% of people between 60-70 years are affected by sarcopenia.  There is an estimated loss of 0.5-1% per year after the age of 25 and this accelerates after the age of 60, doubling in each decade specially in inactive people.
  • 10. Three measures of muscular function and one of muscle mass in men and women 10 Muscle strength and potency diminish with ageing Strength of knee extension Manual pressure Varones Mujeres Varones Mujeres 20 40 60 80 100 20 40 60 80 100 Muscle strength Calf muscle Varones Mujeres Varones Mujeres Lauretani F, et al. J Appl Physiol. 2003;95:1851-1860. (N/dm) Years of age 1000 750 500 250 0 0 (kg) Years of age 80 60 40 0 0 (watios) Years of age 400 320 240 160 80 0 0 60 100 (cm2) Years of age 0 20 100 80 60 40 20 20 40 80 20 40 60 80 100
  • 11. 11 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Phisiopathological Changes  Ageing is associated to changes not only in muscular mass but also in muscle compositiĂłn its properties and contractility.
  • 12. Changes in muscle fibers affect Strength and Potency ReinervatiĂłn Lang T, et al. Osteoporosis Int. 2010;21:543-559. Qualitative changes in muscle Type 1 fibers Type II fibers Motorneurone DenervatiĂłn Ageing Sarcopenia • Increase in type I fibers • Diminution in type II fibers Disminutionl in ttransversal area
  • 13. Senil miosteatosis Miosteatosis • Increase in intermuscular and intramuscular fat Transversal cut of the thigh through resonance Transversal cut of the thigh through tomography
  • 14. Intramuscular fat increase even with a stable body weight Muscle Intermuscular adipose tissue Succutaneous adipose tissue 6 2 -2 * Significativamente diferente respecto al momento basal,p < 0,01 Delmonico MJ, et al. Am J Clin Nutr. 2009;90:1579-1585. Five years longitudinal study Varones Mujeres Evaluation respect to basal moment (%) 8 4 0 -4 -6 -10 -12 * * * *
  • 15. 15 Sarcopenia. A forgotten Cause of Mobility Problems in Old Age Causal Mechanisms  Loss of ability of satellite cells to self multiply  Loss of ability of muscle to respond to anabolic stimuli such as that of Insulin, growth hormone and amino acids.  Insufficient protein in the diet.  Lack of frequent exercise.
  • 16. 16 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Effects of Sarcopenia  Diminution of physical function  Increased disability  Increased dependency  Mobility problems  Increase in health costs
  • 17. Sarcopenia Diminishes Function and Increases disability 0 2 4 6 8 10 Walk 400 meters Climb 10 steps Lift 4,5 kg Walk 2,5 meters Get up 5 times from a chair Hability to take care of themselves Make their own meals Activities of daily living Janssen I, et al. J Am Geriatr Soc. 2002;50:889-896.
  • 18. Sarcopenia has an Elevated Health Cost Men Women Normal Moderate Sarcopenia Severe sarcopenia Normal Moderate Sarcopenia Severe sarcopenia Prevalence 36% 53% 11% 69% 22% 9% Relative risk of disability, % 1.00 3.48 4.60 1.00 1.46 3.15 Cost in US thousand millions - 7.18 3.63 - 2.7 4.96 The direct health cost attributed to sarcopenia in The US in the year 2000 was 18.500 million dollars (nearly 1,5% of the total health cost of that year). Janssen I, et al. J Am Geriatr Soc. 2004;52:80-85.
  • 19. 19 Sarcopenia. A Forgotten Cause of Mobility Problems in Old age Diagnosis Should be stablished when two out of three criteria are met: 1. That there is a reduction in muscle mass. 2. That there is a reduction in muscle strength and/or low exercise tolerance.
  • 20. 20 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Diagnosis  Muscle mass is 2 standard deviations below a population of reference.  Diminution of the walking speed below 0.8 mts/sec in a 4 meters walking trial.  CAT scan, MRI, anthropometry and the valuation of creatinine excretion are also used.
  • 21. 21 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Treatment  Since sarcopenia is due to multiple factors, its prevention and treatment require an integrated approach that should include:  Diet  Hormonal replacement therapy  Nutritional supplements including Vitamin D and  Exercise
  • 22. Protein Synthesis and Muscle Mass • Proteins in the diet stimulate protein synthesis in older people • An increase in the intake of protein > 0,8 g/kg/day - Increase the anabolism of proteins in muscles - Can help to avoid the senile decrease in muscle mass Paddon-Jones D, et al. Am J Clin Nutr. 2008;87:1562S-1566S.
  • 23. Oral Nutritional Supplements plus Resistance Exercises Increase Muscle Strength Design • n = 63 women and 37 men, 87,1 Âą 0,6 years (interval: 72-98) • The strength was measured as a maximal repetition of extensor muscles of the hip and knees after a 10 weeks intervention. RESULTS • In fragile old people you get better results when you associate exercise with oral nutritional supplements. Exercise Control Experimental Group Fiatarone M, et al. N Engl J Med. 1994;330:1769-1775. Variation in strength (%) 500 400 300 200 100 0 -100 -200 Exercise plus supplements Supplements ** *
  • 24. 24 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Hormonal Replacement Therapy  Growth hormone  Mechano growth factor and insulin like growth factor  Testosterone
  • 25. 25 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Exercise
  • 26. 26 Sarcopenia. A Forgotten Cause of Mobility Problems in Old Age Finally  Ageing produces a diminution of muscle mass, strength, and muscular function.  Sarcopenia is defined mainly by the degree of diminution of muscle mass.  Sarcopenia is due to a complex interaction between many factors among those, nutrition.  The diminution of muscle mass in sarcopenia, increases the risk of fragility, mobility problems, disability and has an elevated health cost.  It can be avoided by having a good nutrition and exercising during your life time. These are probably the more efficient public health interventions for this condition.
  • 27. 27 Sarcopenia. A forgotten Cause of Mobility Problems in Old Age !!!!!!!!!! Thank you and let’s start!!!!!!!!!!!
  • 28. Contacts to the presenter: Rosy Pereyra, M.D. President ILC-DR (809) 449-9551 rosy.pereyra@gmail.com
  • 29. Are we living longer and healthier? Exploring gender differences in health expectancy among older Singaporeans Susana Concordo Harding Director ILC-Singapore This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 30. For more information about this presentation, please contact Susana Concordo Harding at susanaharding@tsaofoundation.org This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 31. Prevalence and risks factors for falls, and the impact on mobility in later life: The Cape Town study Dr Sebastiana Kalula Director ILC-South Africa This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 32. Ageing and mobility: Impact of falls – the Cape Town study Sebastiana Kalula ILC South Africa University of Cape Town
  • 33. Falls are a major cause of morbidity and mortality, and contributor to impaired functioning and mobility in older people
  • 34. Long lie (>1 hour) • Pneumonia • Dehydration • Pressure sores Social • Social withdrawal • Institutionalization Impact of a fall Functional • Immobility • Deconditioning • Decreased righting reflex Psychological • Fear of falls • Loss of confidence • Depression • Increased dependency Physical injuries • Bruises • Head injury • Fractures Source: Grimm and Mion 2011; Lord et al., 2001, Donald and Bulpitt 1999, Tinetti and Williams 1997
  • 35. Impact of hip fractures • 2 % of falls result in hip fracture • 25 % die within 6 months • 60 % have restricted mobility • Management and social costs are high Sources: Chu et al., 2006; O’Loughlin et al., 1993; Tinetti et al., 1988.
  • 36. Although prevalence and incidence rates of falls are well established in high income countries, little is known on falls in low to middle income countries, particularly in sub-Saharan Africa South Africa is listed as a middle income country, but has a large poor population
  • 37. Africa region studies Information on falls in older persons in Africa is sparse • Single study in Rwanda (Ntagungira, 2005) focused on older persons who had fallen; recurrent fallers constituted 23.3 % • Single retrospective study in Nigeria (Bekibele and Gureje, 2010) established a fall prevalence rate of 23 % • Until now, no information in South Africa
  • 38. Cape Town study on falls Surveyed 837 community-dwelling older persons with a 12-month follow-up Sample size 837 aged ≥ 65 years • Gugulethu n=231 (black Africans) • Plumstead n=145 (whites) • Wynberg n=264 (coloureds (mixed ancestry)) Follow up sample n=632 Kalula, 2012
  • 39. Prevalence of falls: Cape Town study • At baseline: 26.4 % Recurrent falls: 11 % • At follow-up: 22 % Recurrent falls: 6.3% • Incidence rate: 367 per 1000 person years – 236 per 1000 person years for men – 405.7 per 1000 person years for women • Recurrent falls more common in women: 82.5 %
  • 40. Fall prevalence by ethnic group: Cape Town study Whites n 140 % 42.9 Coloureds 392 34.4 Black Africans 283 6.4
  • 41. Risk factors for falls: Cape Town study Independent risk factors for a fall were mainly self-reported conditions: • Medical conditions (poor mobility, poor vision, poor urine control, depression, Parkinson’s disease) • Self-rated poor health status • Medication use (antidepressants, anti-inflammatory drugs)
  • 42. Ethnic differences in risk factors Occupation category (%) Reference Black African n = 283 Whites n = 140 OR (95% CI) Unskilled 221 (78.1) 12 (8.6) 1 Skilled 58 (20.5) 94 (67.1) 30 (15–58)* Managerial 4 (1.4) 34 (24.3) 157 (47–513)* Health compared to a year ago (%) ‒ Worse 15 (5.3) 9 (6.4) 2.17 (0.85 – 5.58) Mobility ‒ With difficulty 47 (16.6) 20 (14.3) 0.84 (0.47 – 1.48) Total number in household (median, IQR)) 7 (5-8.5) 2 (1-3) 0.32 (0.26 – 0.38)* *P value = <0.001
  • 43. Characteristic Reference Black African n = 283 White n = 140 OR (95% CI) Age in years (median, (IQR)) 74 (69-78) 76.5 (70-81) 1.04 (1.01–1.08)# Comorbidities (median, (IQR)) 3 (2-4) 4 (2-5) 1.39 (1.18 – 1.52)* Number of drugs (median, (IQR)) 3 (1-4) 4.5 (2-7) 1.36 (1.25 – 1.49)* Self-reported depression (%) Yes 23 (8.1) 21 (15.0) 2.00 (1.06 – 3.75)* Geriatric Depression Scale score 1 (1-6) 2 (1-3) 0.89 (0.83 – 0.97)$ Use of psycholeptics (%) Yes 1 (0.4) 13 (9.3) 28.87 (3.74–223.0)* Self-rated health (%) Poor 228 (80.6) 25 (17.9) 0.05 (0.03 – 0.09)* p value: * < 0.001, # =0.006, $= 0 005
  • 44. Occupation category (%) Reference Black African n = 283 White n = 140 OR (95% CI) SES Index score 6 (5 – 6) 8 (8 – 8) 5.23 (3.94 – 6.94)* Cognitive score 8 (4 – 12) 2 (0 – 5.7) 0.83 (0.79 – 0.87)* Hand grip strength (kg) 14 (10.5–19) 16 (11 – 22) 1.04 (1.01 – 1.06)* One leg stand eyes 3 (1 – 7) 13 (6 – 26) 1.14 (1.11 – 1.17)* open (seconds) One leg stand eyes shut (seconds) 1 (0.0 – 4.0) 3 (2.0 – 6) 1.13 (1.07 – 1.19)* Up & Go test (seconds) 20 (18 – 23) 12 (10 – 16) 0.89 (0.86 – 0.92)* Chair stands (seconds) 20 (19 – 22) 12. (10 – 15) 0.79 (0.73 – 0.82)* SES= Socio-economic Status index; score of 8 items in household; * p value: < 0.001
  • 45. Falls and medical help: Cape Town study • At baseline, 72 per cent reported injury resulting from a fall and 42 per cent sought medical help for the injury • At follow-up, 70 per cent reported injury and 38 per cent sought medical help
  • 46. Consequences of a fall: Cape Town study Baseline Follow-up % % • Injuries - soft tissue 69.7 68.1 - fractures 14.4 5.7 • Fear of falls 53.9 60.1 • Not fully recovered 41.7 39.4
  • 47. Environmental hazards for falls: Cape Town study Surveyed 837 older persons Outdoors N (%) Indoors N (%) Stairs/steps 293 (35) Slippery floor 221 (26.4) Road (uneven surface, 86 (10.3) Mats/loose carpet 189 (22.6) potholes, stones, road works, slippery) Ground (stones, sand, uneven) 53 ( 6.3) Children/pets/toys 54 (6.5) Garden (furniture, toys, plants, hose, washing line) 21 (2.5) Stairs/steps 52 (6.2) Veranda (slippery, uneven, holes) 20 (2.4 Furniture 37 (4.4) Pavement (people, uneven, rubble, banana peels, cracks) 19 (2.3) Getting out of a bath 31 (3.7)
  • 48. Findings and questions • Finding of marked ethnic differences in fall prevalence was unexpected and raises questions • Speculated that life-time manual labour preserves gait and balance in the relatively deprived black African sub-sample, hence a low fall rate • Far lower fall rate in black Africans despite high poverty levels and more environmental hazards in their residential area
  • 49. Recommendations • Design and implement falls intervention programmes to sustain mobility • History taking, rather than tests, is a more reliable tool for clinicians to identify those at risk of a fall who could benefit from intervention • Educate and train health professionals in screening for falls, and management of risk factors and consequences of a fall
  • 51. MOBILAGE Dr Didier Halimi ILC-France This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 52. MOBILAGE D. HALIMI (ILC-France) on behalf of BROCA Hospital, CEREMH, RATP and ILC-France ILC Gobal Alliance Mobility Symposium London 10.29.14 52
  • 53. MOBILAGE: MOBILITY FOR ALL ! ILC Gobal Alliance Mobility Symposium London 10.29.14 53
  • 54. MOBILAGE The situation • Outdoor mobility of older people is – a matter of freedom , preservation of autonomy, psychological & social wellbeing – essential for prevention of dependency • Loss of mobility has negative consequences – depressive symptoms after cessation of driving (Marottoli, 1997) • Driving remains the favourite mode of transportation – for > 50% of people 75 + (Sofres 1990-2000) – driving ability should to be assessed • potentially impacted by physical, sensory or cognitive deficits • to ensure secure driving as long as possible – Alternatives should be proposed if ability to drive is impaired ILC Gobal Alliance Mobility Symposium London 10.29.14 54
  • 55. MOBILAGE The project • To evaluate outdoor mobility of pre-frail and frail elderly and their caregivers through workshops and training focusing on mobility • Objectives • Identify the risks of decreased mobility1 • Analyze participants’ mobility1 • Propose tailored training • Walking in public area , • Driving, cycling, public transportation1 • Inform on alternative outdoor mobility aids • support patients and their families in their implementation2,3 • This pilot project will include – 100 pre-frail and frail subjects 75 or older – re-evaluated after 6 months. 1: BROCA Hospital; 2: CEREMH ; 3: RATP ILC Gobal Alliance Mobility Symposium London 10.29.14 55
  • 56. MOBILAGE Why should I participate? • I am embarrassed by certain movements • I reduced the frequency of my outings • I am concerned about my mobility • I find it hard to get around • I do not feel confident while driving • I am curious to test new devices • I do not feel confident in public transport and I use them less ILC Gobal Alliance Mobility Symposium London 10.29.14 56
  • 57. MOBILAGE Who will benefit ? • Patients, relatives and professionals in gerontology will directly or indirectly benefit from this program • Communication of results will help educate the public about the issue of elder’s mobility ILC Gobal Alliance Mobility Symposium London 10.29.14 57
  • 58. MOBILAGE In practice First step Mobility evaluation and needs assessment of pre-frail and frail persons or their caregivers after medical evaluation and sensory testing ( BROCA Hospital) Second step if the person is eager to learn more about the potential benefits of the MOBILAGE program • Awareness and testing session • Theoretical training: traffic laws and road signalling • Practical training: driving assessment with a driving instructor (and a psychomotor therapist if needed), bicycles, tricycles, adapted scooters, use of public transportation … ILC Gobal Alliance Mobility Symposium London 10.29.14 58
  • 59. MOBILAGE Where are we? • 72 pre-frail and frail people or their caregivers have accepted the mobility screening (first step) • 16 have attended the mobility workshops ( second step ) to get – additionnal information on new mobility aids and to test them – And/or driving support • Limitations – Fear of taking the plunge – Availability for the workshops – Budget and technical maintenance for the new mobility aids ILC Gobal Alliance Mobility Symposium London 10.29.14 59
  • 60. MOBILAGE The Partners ILC Gobal Alliance Mobility Symposium London 10.29.14 60 CEntre of REsources & Innovation Mobility & Handicap Non profit organisation National Centre of Expertise for technical aids for Mobility by the CNSA Paris Public Transportation Network BROCA Hospital
  • 61. Draisine (draisienne) a walking aid that allows you to move while sitting upright ILC Gobal Alliance Mobility Symposium London 10.29.14 61 Awareness and discovery of new mobility solutions
  • 62. Adapted Scooters For people who walk and want solution to increase their mobility perimeter ILC Gobal Alliance Mobility Symposium London 10.29.14 62 Awareness and discovery of new mobility solutions
  • 63. Different adapted cycles: bicycles, tricycles, and electrical cycles ILC Gobal Alliance Mobility Symposium London 10.29.14 63 Awareness and discovery of new mobility solutions
  • 64. Balance learning to ... ... Control the bike, or simply regain confidence. ILC Gobal Alliance Mobility Symposium London 10.29.14 64
  • 65. Individual or small group sessions to learn safe city traffic ILC Gobal Alliance Mobility Symposium London 10.29.14 65
  • 66. Theoretical training: Refresh regulation and signalling ILC Gobal Alliance Mobility Symposium London 10.29.14 66
  • 67. Driving school: driving sessions with practical advice to regain confidence. ILC Gobal Alliance Mobility Symposium London 10.29.14 67
  • 68. Support to use Public Transportation Albertine takes the bus! ILC Gobal Alliance Mobility Symposium London 10.29.14 68
  • 69. CONCLUSION • Outdoor mobility is key for the wellbeing and the preservation of autonomy • MOBILAGE is a valuable experiment, stressing – The importance of a correct evaluation of the mobility and needs of the pre-frail and frail persons and their caregivers – The need for some support services to increase the adherence of the persons to the proposed solutions ILC Gobal Alliance Mobility Symposium London 10.29.14 69
  • 70. This presentation has been made possible thanks to: • Broca Hospital: Marie-Laure SEUX, Laure CAILLARD, MĂŠlanie CORNUET • CEREMH: Claude DUMAS, Antoine VERNIER, Elisabeth JOSEPH • RATP: Jean-Pierre TEXIER 70 ILC Gobal Alliance Mobility Symposium London 10.29.14
  • 71. ILC-France • Françoise Forette, MD • Marie-Anne Brieu, MD • Philippe Guillet, MD • Jean-Claude Salord, MD • Didier Halimi, MD ILC Gobal Alliance Mobility Symposium London 10.29.14 71
  • 72. Short Comfort Break This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 73. Maintaining Older People’s Mobility: What Do We Need? Kunio Mizuta President ILC-Japan This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 74. Maintaining Older People’s Mobility: What Do We Need? To Promote Older People’s Independence “Aging and Mobility,” ILC- Global Alliance Conference October 29, 2014 London Kunio MIZUTA President, ILC-Japan 74
  • 75. 1. Demographic Trends in Japan Population Aging: Estimates & Projections 75 % of the elderly: 7.9% (1975) ⇒ 25.1% (2013) ⇒ 30.3% (2025) # of the old-old: 2.8mil.(1975) ⇒ 15.5mil.(2013) ⇒ 21.8mil. (2025) 9.0 15.6 6.0 2.8 13.0 75.8 86.2 16.3 79.0 21.8 14.8 70.8 23.9 13.8 50.0 27.2 18.5 16.4 13.2 9.4 140 120 100 80 60 40 20 0 1975 2000 2013 2025 2050 75- 65-74 15-64 0-14 Total: 111.9 % of 65+: 7.9% million people 126.9 17.4% 97.1 38.8% 120.7 30.3% 127.3 25.1% Cabinet Office (2014). Annual Report on the Aging Society
  • 76. 2. Significance of Mobility among Older People, Research Supporting “LTC Prevention” Programs Reasons for Needing Care Many people start needing care due to locomotor disabilities Cerebro-vascular disease (Stroke) Joint disorder, fracture, fall Demen-tia Age-related frailty Cardiac (heart) disease Other, unknown Total 21.5 21.1 15.3 13.7 3.9 24.5 Male 32.9 11.3 10.9 10.5 4.5 29.9 Female 15.9 25.8 17.5 15.3 3.7 21.8 76 Reasons for needing care by sex (%) Ministry of Health, Labour and Welfare (2012). Comprehensive Survey of Living Conditions.
  • 77. Older People’s Walking & IADL Walking speed is an important health indicator. Programs to increase motor function can be effective. ◆ First sign of disability: Loss of ability to walk. Then problems with toileting and eating. ◆ A longitudinal study (5 year follow-up study) shows that the groups with slower walking speed are at higher risk for IADL decline (slowest group: 23%, fastest group: 5%). ◆ An exercise intervention study for older people proves that a program to increase motor function improves physical function (walking speed, MCS) and mental health (WHO-5). Suzuki, T. (2012). The Basics on a Hyper-Aged Society (pp.42-43). Kodansha Gendai Shinsho. Ohbuchi, S., et al. (2010). Research on comprehensive evaluation and analyses regarding long-term care prevention. In T. Suzuki et al. (eds), Report on a Comprehensive Research Project Regarding Long-Term Care Prevention (p.33). Japan Public Health Association. 77
  • 78. Lower frequency of going out is an independent risk factor for problems w/ walking and cognitive function ◆ A longitudinal study shows: Frequency of going out: 3 groups “1+/day” “1/every few days” “<1/week” (Odds ratios at the 2-yr. follow-up study) Problem w/ walking 1.00 1.78 4.02 Problem w/ cognitive function 1.00 1.58 3.49 78 Frequency of Going Out & Older People’s Health Fujita, K., et al. (2006). Frequency of going outdoors as a good predictor for incident disability of physical function as well as disability recovery in community-dwelling older adults in rural Japan. Journal of Epidemiology, 16 (1), 261-270.
  • 79. ◆A longitudinal study examined what effects the total hours of productive activities have on older people’s health (3 year follow-up study) Significant differences in ADL (going out, standing up from a chair/bed, going to the toilet, etc.) and cognitive impairments (SPMSQ score) Shibata, H., Sugihara, Y., & Sugisawa, H. (2012). Social contribution by middle-aged and older Japanese: Its contributing factors and effects on physical and emotional well-being. Analyses of 2 representative panel data. Applied Gerontology, 6, 21-38. 79 Hours of Activities & Levels of ADL Cognitive Productive acImtivpitaieirsm caenn tpsrevent ADL and cognitive impairments
  • 80. Summary of Existing Studies 1. A significant number of people start needing care due to locomotor disabilities. 2. Speed of walking is an important health indicator among older people. 3. Lower frequency of going out is a risk factor for problems with walking and cognitive function. 4. Programs to increase motor function can be effective. 5. Productive activities can prevent ADL and cognitive impairments. 80
  • 81. 3. Comprehensive Community Care & Long-Term Care Prevention Comprehensive Community Care (providing integrated community support, including housing, health care, LTC, preventive care and assistance w/ daily living, so that people can stay in a familiar environment) ◆Within the frame of CCC, municipalities are urged and supported to make efforts to prevent frailty by maintaining and restoring older people's motor function through evidence-based way of exercise. ◆Active participation by residents, especially older people and community as a whole is essential. 81 Long-term care prevention service, Sakai city, Fukui prefecture
  • 82. 4. Other Measures to Promote Locomotor Health & LTC Prevention Basic Health Check List for Those Over 65years Old is distributed to about 50% of the elderly population by local municipalities, and about 30% of older people fill it out. 82 Health Checkups for LTC Prevention Questionnaires 1 daily life Do you normally travel by bus or train by yourself? Do you go out and buy daily necessities by yourself? Do you manage your own deposits and savings at the bank? Do you often go out to visit your friends? Do you consult with your family or friends about their problems? 2 physical ability Are you able to go upstairs without holding rail or wall? Are you able to stand up from the chair without any aids? Are you able to keep walking for about 15 minutes? Do you worry about falling down? … … ŠAMDA International Medical Information Center 2008
  • 83. Prevention of “Locomotive Syndrome” 83 “Health Japan 21” Campaign (Ministry of Health, Labour and Welfare) “The Locomotive Challenge! Council” (The Japanese Orthopaedic Association + private enterprises) Bones Muscles Joints Bone strength Fall/fracture Sarcopenia Burden on joint/inflammation Mobility Limited activities/social participation Needing care
  • 84. Measures to Build a Better Environment to Improve Mobility Barrier-Free Act (Enacted in 2000, revised in 2006) Ensuring independent living for older people & those w/ disabilities ◆ Promoting barrier-free design: Streets, parks, buildings, public transportation, etc. ◆ Focused efforts to promote barrier-free design: Around stations and areas frequently used by older people and those w/ disabilities 84
  • 85. Mobility Support Project 85 Ubiquitous Tanba Sasayama Reading QR codes + Providing WiFi positional info Internet (WiFi service) QR Code System configuration & available contents Routing assistance Info on facilities Info on restrooms Bus timetables Providing contents (content server) Walking space network data
  • 86. Conclusion ◆ Maintaining and improving older people’s mobility are tools to promote their social participation. Programs to maintain and improve mobility cannot be effective without older people’s positive attitude toward a society. ◆ That is, we can pave the way for a hyper-aged society based on the concept of Productive Aging. 86
  • 87. Loss of mobility, loss of Autonomy, loss of quality of life Lia Daichman President ILC-Argentina This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 88. -ARGENTINA “LOSS OF MOBILITY, LOSS OF AUTONOMY, LOSS OF QUALITY OF LIFE” LIA SUSANA DAICHMAN MD CYNTHIA MARIÑANSKY MD MAG. SOFÍA APTEKMAN SW ROSANA SILBERMAN SW London, Oct. 2014
  • 89. INTRODUCTION -ARGENTINA Life-space scales have been developed to assess movement of individuals from home to beyond town or region in contrast with classic measures of mobility that do not take into account the interaction with the living environment.
  • 90. DEMOGRAPHY -Argentinean total population: 40.117.096 persons corresponding 5.725.838 to people 60 years and older - People over 65 years of age represent 10.2% 14.3% are 60 years old and over. - Middle life expectancy at birth is around 75.5 years, 72.5% for males and 80% for females. •The proportion of seniors in Argentina is the third [1] highest in the Latin American Region after Uruguay and Cuba. -ARGENTINA
  • 91. GROUP PROFILE: ANALYSIS Gender: 82% females N = 50  Average age: 77.1 years, (77.5 (F) and 75.4(M)  Education: 54% high school; 7% university; Income: 80% believed “sufficient”  Health: 76% perceived themselves to be in a good health  Marital status: 44% widows; 36% married; 6% divorced; 14% single (exceed the rate of the City of BsAs) -ARGENTINA  Living arrangements: 66% with other people; 44% living alone.
  • 92. RESULTS -ARGENTINA  Cognitive functioning: 84% normal; 16% had some difficulties.  Depressive symptoms: 70% showed no depressive symptoms; 30 % presented depressive symptoms.  Physical limitations: 58 % had no difficulty with the Chair Test; 20 % had some difficulties; 22% could not perform the test at all.  ADL: 84% had no difficulty; 16% require assistance  Space Life: 52% were above 87 points; 32% between 56 and 87 points and 16% below the 56 point line which is considered risk (highest 120 points)
  • 93. -ARGENTINA HIGHLIGHTS Differed according to previous personalities and coping mechanisms through their life cycles. Nearly 70% expressed that their lives would be highly impaired in the case they should have to remain at home: - “I would commit suicide because I love my home and activities” - “I cannot even think about it” - “I really never thought about it” - “I would lose my freedom, I would become a slave” - “I would be depressed, I wouldn´t like to live like that” - “I would lose my job, the one I depend on.” -“I would adapt myself, I would look for company and help” – -“I expect it won’t happen, it would be very hard”
  • 95. -ARGENTINA DISCUSSION - A high percentage of our population expressed that a situation like this would influence on their emotional state by means of depression, sadness, anguish, anxiety about the future and helplessness… -The vast majority of people admitted that they would need help. (It seems that FAMILY would be the first answer). - Nevertheless, a fair number of people, who would accept help, do not mention family as their first resource. More than that, they explicit would feel pretty bad about having to rely on their children or grandchildren for informal care. - Older sons and daughters, more than often take care of their own - grandchildren and when they have to look after their older parents, even if they privilege the little ones, they find themselves in a difficult position which they cannot escape and have little choice… .
  • 96. RECOMMENDATIONS -ARGENTINA •Inform and prepare older person, their families and the community in general about what to do and how to deal with gradual or sudden loss of autonomy’ situations. •Work with Focus groups or special courses for older persons addressing risk factors related to this age group and generate alternative projects that extend and strengthen existing and new networks of support. •Create specialized public and private centers for advice and support to older persons and their families to be used as required. •Promote programs and awareness workshops on intergenerational solidarity to facilitate inclusion of older adults in need of care
  • 97. RECOMMENDATIONS -ARGENTINA • Stimulate more public and private policies to build or improve and adapt homes for older people for present and future needs. • Sensitize the population about the importance of home safety to  prevent accidents. • Promote within the community the importance of physical activity, health care and active ageing to prevent deterioration and disability. • Encourage individual, intergenerational and community social, exchange, including older persons, to promote the consolidation of support networks at a useful level when necessary. • Work individually or in groups, in terms of medical and social services, to avoid, prevent, and support sensory deprivations as well as all types of MOBILITY’s loss.
  • 98. Thank you very much from Buenos Aires!.. -ARGENTINA liadaichman@fibertel.com.ar
  • 99. Local and national initiatives to support active ageing and improve quality of long-term care in the Czech Republic Dr Iva HolmerovĂĄ President ILC-Czech Republic This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 100. Local and national initiatives to support active ageing and improve quality of long-term care in the Czech Republic Iva HolmerovĂĄ, Petr Wija ILC-Czech Republic
  • 101. Healthy Life Expectancy (Wija 2012) 2011 Ĺženy muĹži hly 63,6 62,2 le 80,7 74,7 % hly 78,8% 83,3% rozdĂ­l muĹži Ĺženy: 6 let (LE), 1,4 let (HLY)
  • 103. Future need of long-term care will depend on (EC 2013): • – Numbers of persons 80+ • – Health status of population, healthy life expectancy, chronic diseases and multimorbidity – Ability to live in home environment despite disability
  • 104. Enabling model of geriatric care (P.Millard, 1994) Acute care – dg and treatment Rehabilitation Long-term care Functional improvement
  • 105. Disabling model of geriatric care (P.Millard, 1994) Dg and th RHB Long-term care Underestimation of geriatric care needs – fixation of disability
  • 106. BEDEKR Guide on Active Ageing or How to find the way in the landscape of active ageing and long-term care HolmerovĂĄ I., StarostovĂĄ O., VepřkovĂĄ R., Wija P.
  • 107. BEDEKR  Support of active ageing on the community level  Participation and communication with local authorities  Independent living  Environment and mobility
  • 108. BEDEKR  Intergenerational activities  Voluntary work  Education  ICT literacy and internet  Social activities  Physical activity and sports
  • 109. BEDEKR Mobility: - Important aspect of quality of life - Necessary for self-maintenance Individual level (rehabilitation, support, aids) Community level – no barriers, transport Societal level - enabling environment
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  • 115. CELLO – ILC – CZ • Thanks to: • Dana HradcovĂĄ – GOS Project and CELLO Coordinator • Marcela JanečkovĂĄ – FRAM Project • Olga StarostovĂĄ – FRAM Project • Radka VepřkovĂĄ – FRAM Project • Hana VaňkovĂĄ – IGA and GOS Project • Petr Veleta – GOS Project
  • 116. Panel Response Marieke van der Waal Director, ILC-Netherlands Jayant Umranikar ILC-India This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance
  • 117. Ageing and Mobility: ILC Global Alliance Symposium Wednesday 29th October 2014 This event is kindly supported by Alliance Boots and hosted by the LGA #ilcglobalalliance