This chapter discusses the theological, geopolitical, and organizational challenges that Christian mission work will face in the future. Theological tensions may increase as postmodernism spreads. Missionaries may have to minister in the midst of unprecedented global crises. Emerging church models like megachurches, African initiated churches, and base communities may drive missionary efforts in the 21st century. Mission agencies will need new financial support models and risk criticism for being outdated. However, the document concludes that God will equip missionaries for whatever challenges come to spread the Gospel worldwide.