Under a Corporate Integrity Agreement, organizations must report certain incidents to the OIG within 30 days, such as legal or compliance issues that affect patient safety or quality of care. A material breach of the agreement, like failing an audit or interfering with an investigation, could result in exclusion from participating in federal healthcare programs. Independent Review Organizations that audit organizations must be objective to ensure accurate reviews, as a breach of the agreement by an organization would require stipulated financial penalties to be paid.