This document summarizes a presentation on the benefits of CIRCOVAC vaccination in a large Bulgarian pig farm. The farm saw improvements after implementing CIRCOVAC vaccination of sows and piglets, including increased total born and weaned piglets per litter. Pig growth was also improved with increased average daily weight gain. The regular sow and piglet vaccination protocol with CIRCOVAC was found to provide the best performance benefits for the farrow-to-finish farm over a period of more than 3 years.
This document discusses respiratory disorders in pigs, including swine influenza. [1] Swine flu can cause fever, coughing, weight heterogeneity in young pigs, and secondary infections. [2] It leads to lower productivity and increased use of antibiotics and labor. [3] The speaker discusses control measures for swine flu including vaccination, though uptake varies widely between countries and regions.
VAXXITEK HVT + IBD - Field Study - Brazil - MerialMerial EMEA
This document summarizes the field experience of using Vaxxitek HVT+IBD vaccine in broilers in Copacol Parana, Brazil over 6 months and 450 flocks totaling 7.2 million birds. The experimental group received a single dose of Vaxxitek HVT+IBD in ovo, while the standard program used Marek's disease vaccine in ovo and two intermediate IBD vaccines by drinking water. Results showed the Vaxxitek group had lower mortality, slightly better feed conversion ratio, older age, lower condemnation rates, and higher body weight compared to the standard program. Vaxxitek provides benefits of improved production performance and lower condemnation rates.
Dr. Phil Gauger - Influenza ‘A’ Virus in Swine: Overview of Disease and Diagn...John Blue
Influenza ‘A’ Virus in Swine: Overview of Disease and Diagnosis - Dr. Phil Gauger, Iowa State University Veterinary Diagnostic Laboratory, from 2015 Summer Swine Health Seminar, August 22, 2015, Wrightsville Beach, North Carolina, USA.
More presentations at http://www.swinecast.com/2015-boehringer-ingelheim-carolina-swine-health-seminar
Current updates of swine mycoplasma vaccinesMamta Singh
Current measures do not provide sustainable control of the disease, although they are beneficial from an economic point of view,efforts to develop a more effective vaccine against swine mycoplasma have been proposed and vaccines developed using recombinant DNA technology represents a viable alternative
The document summarizes the experience of a Bulgarian pig farm with the CIRCOVAC vaccine for porcine circovirus. The farm saw improvements in several key performance metrics after beginning regular vaccination of sows and piglets with CIRCOVAC, including increased litter size, higher average daily weight gain, and fewer days to reach 100kg. Overall, the farm concluded that CIRCOVAC helped enhance reproductive performance, improve pig growth, reduce time to slaughter, and provide sustained protection against porcine circovirus disease for piglets.
This document summarizes research on PCV2 vaccination protocols used in British pig production. Two field trials found that vaccinating sows with Circovac and piglets with either Circovac or Circoflex showed no significant differences in growth rates or mortality. Numerical advantages were seen in pigs vaccinated with Circovac in both trials. The document concludes that under field conditions, Circovac and Circoflex perform similarly as PCV2 vaccines for piglets.
- The document discusses pig production in Spain and the author's experience vaccinating piglets against PCV2 (porcine circovirus type 2) using the Circovac vaccine.
- Problems with poor performance and increased mortality led the author to test for PCV2, finding it present. Vaccinating piglets resulted in reduced mortality, improved growth and feed efficiency, and economic benefits.
- However, the vaccine's effects can be limited if PRRS (porcine reproductive and respiratory syndrome) is also present, and both PCV2 and mycoplasma vaccines may be needed in some farms. Ongoing monitoring and adaptation is important.
Henry Too presented on pig production in Asia and experiences with Circovac®. Pig farming ranges from small backyard operations to commercial farms. Circovac® is registered for use in several Asian countries and has been shown in trials to significantly reduce mortality and PCVD-specific mortality, improve growth rates, reduce time to slaughter, and decrease viral shedding compared to non-vaccinated pigs. The results demonstrate Circovac® is effective at controlling PCV2 infections across the whole herd through sow or piglet vaccination.
This document discusses respiratory disorders in pigs, including swine influenza. [1] Swine flu can cause fever, coughing, weight heterogeneity in young pigs, and secondary infections. [2] It leads to lower productivity and increased use of antibiotics and labor. [3] The speaker discusses control measures for swine flu including vaccination, though uptake varies widely between countries and regions.
VAXXITEK HVT + IBD - Field Study - Brazil - MerialMerial EMEA
This document summarizes the field experience of using Vaxxitek HVT+IBD vaccine in broilers in Copacol Parana, Brazil over 6 months and 450 flocks totaling 7.2 million birds. The experimental group received a single dose of Vaxxitek HVT+IBD in ovo, while the standard program used Marek's disease vaccine in ovo and two intermediate IBD vaccines by drinking water. Results showed the Vaxxitek group had lower mortality, slightly better feed conversion ratio, older age, lower condemnation rates, and higher body weight compared to the standard program. Vaxxitek provides benefits of improved production performance and lower condemnation rates.
Dr. Phil Gauger - Influenza ‘A’ Virus in Swine: Overview of Disease and Diagn...John Blue
Influenza ‘A’ Virus in Swine: Overview of Disease and Diagnosis - Dr. Phil Gauger, Iowa State University Veterinary Diagnostic Laboratory, from 2015 Summer Swine Health Seminar, August 22, 2015, Wrightsville Beach, North Carolina, USA.
More presentations at http://www.swinecast.com/2015-boehringer-ingelheim-carolina-swine-health-seminar
Current updates of swine mycoplasma vaccinesMamta Singh
Current measures do not provide sustainable control of the disease, although they are beneficial from an economic point of view,efforts to develop a more effective vaccine against swine mycoplasma have been proposed and vaccines developed using recombinant DNA technology represents a viable alternative
The document summarizes the experience of a Bulgarian pig farm with the CIRCOVAC vaccine for porcine circovirus. The farm saw improvements in several key performance metrics after beginning regular vaccination of sows and piglets with CIRCOVAC, including increased litter size, higher average daily weight gain, and fewer days to reach 100kg. Overall, the farm concluded that CIRCOVAC helped enhance reproductive performance, improve pig growth, reduce time to slaughter, and provide sustained protection against porcine circovirus disease for piglets.
This document summarizes research on PCV2 vaccination protocols used in British pig production. Two field trials found that vaccinating sows with Circovac and piglets with either Circovac or Circoflex showed no significant differences in growth rates or mortality. Numerical advantages were seen in pigs vaccinated with Circovac in both trials. The document concludes that under field conditions, Circovac and Circoflex perform similarly as PCV2 vaccines for piglets.
- The document discusses pig production in Spain and the author's experience vaccinating piglets against PCV2 (porcine circovirus type 2) using the Circovac vaccine.
- Problems with poor performance and increased mortality led the author to test for PCV2, finding it present. Vaccinating piglets resulted in reduced mortality, improved growth and feed efficiency, and economic benefits.
- However, the vaccine's effects can be limited if PRRS (porcine reproductive and respiratory syndrome) is also present, and both PCV2 and mycoplasma vaccines may be needed in some farms. Ongoing monitoring and adaptation is important.
Henry Too presented on pig production in Asia and experiences with Circovac®. Pig farming ranges from small backyard operations to commercial farms. Circovac® is registered for use in several Asian countries and has been shown in trials to significantly reduce mortality and PCVD-specific mortality, improve growth rates, reduce time to slaughter, and decrease viral shedding compared to non-vaccinated pigs. The results demonstrate Circovac® is effective at controlling PCV2 infections across the whole herd through sow or piglet vaccination.
This document discusses strategies for controlling Porcine Circovirus Type 2 (PCVD) in pigs. It notes that the disease has changed over time from an acute to a chronic form. Three main factors determine the risk of PCVD: high viral pressure, poor passive immunity in piglets, and young age at exposure. Vaccination of sows provides passive immunity to piglets while vaccination of piglets provides active immunity. The optimal strategy depends on farm size, co-infections present, and reproductive performance goals. A basic program vaccinating only sows is most cost-effective while a complete program vaccinating sows and piglets provides maximum protection. Future segmentation of farms may involve basic programs for small farms and assault or
Vila et al. Improvement of herd performance parameters after sow and piglet v...Merial EMEA
This document summarizes the results of a case study conducted on a 2,700 sow farm in Bulgaria that implemented a full herd vaccination program against PCV2 using CIRCOVAC. The program involved vaccinating piglets at 28-30 days and sows. Results showed improvements in herd performance parameters, including increased litter size from 13 to 17.8 total born piglets, decreased days to 100kg by 5.3 days, improved daily weight gain, and stabilized health status by decreasing gastric ulcers and respiratory signs. The owner considers CIRCOVAC vaccination as a key tool for farm management and competitiveness.
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
Natural Infection, Immunity & Prevalence of PCV2 - Dr. Michael Murtaugh and Dr. Cheryl Dvorak, University of Minnesota, USA , from the Boehringer Ingelheim Pre-AASV Conference, February 28, 2014 - Dallas, TX
More presentations at http://www.swinecast.com/2014-boehringer-ingelheim-aasv
The document summarizes a 3-year field study on the use of CIRCOVAC piglet vaccination in 69 French farms. The main findings were:
1) Over 500,000 piglets were vaccinated between 3-6 weeks with good safety and most farmers continued vaccination.
2) There was a significant reduction in mortality rates and a sharp increase in average daily gain (ADG), reducing fattening periods by up to 20 days.
3) Focusing on 3 farms in more detail, vaccination was associated with decreased mortality, increased carcass weight and homogeneity, and reduced lung lesions compared to non-vaccinated piglets.
The document reports on Muhammad Tanveer Shah's 16-week internship at the Government Poultry Farm in Quetta from September 19, 2011 to January 8, 2012. The farm breeds layers and broilers for commercial egg and meat production. Management of the layers and broilers involves selection of breeds, housing, feeding, vaccination schedules, and disease control protocols carried out on a weekly basis to optimize production.
Bi pre aasv health seminar castro ppt (1) dw020810 sans picsJohn Blue
This document summarizes the experience of a Chilean pig farm with porcine circovirus type 2 (PCV2) and different PCV2 vaccination protocols from 2007-2009. It finds that vaccination with Ingelvac CircoFLEX at 20 days of age resulted in lower attrition, culling, and mortality rates compared to vaccination with Circumvent from 5-21 days of age or no vaccination. Average marketed pigs per period were also highest with CircoFLEX vaccination. Mortality rates were highest during a PCV2-associated disease (PCVAD) outbreak when no vaccination was used. Intestinal torsion was a top cause of mortality.
Bi pre aasv health seminar castro ppt (1) dw020810 sans picsJohn Blue
This document summarizes the experience of a Chilean pig farm with porcine circovirus type 2 (PCV2) and different PCV2 vaccination protocols from 2007-2009. It finds that vaccination with Ingelvac CircoFLEX at 20 days of age resulted in lower attrition, culling, and mortality rates compared to vaccination with Circumvent at 5-21 days of age or no vaccination. Average marketed pigs per period were also highest with CircoFLEX vaccination. Mortality rates were highest during a PCV2-associated disease (PCVAD) outbreak in 2007 before vaccines were widely used. Intestinal torsion was a top cause of mortality.
Dr. Barry Kerkaert - Applying Research to Decision Making to Maximize Returns...John Blue
Applying Research to Decision Making to Maximize Returns at Pipestone - Dr. Barry R. Kerkaert, Director of Grow Finish Management, Pipestone Vet Clinic, from the 2012 Boehringer Ingelheim Swine Health Seminar, August 9-11, 2012, Wrightsville Beach, NC, USA.
More presentations at http://www.swinecast.com/2012-boehringer-ingelheim-carolina-swine-health-seminar
Dr. Joe Cassady - Effects of preweaning factors on sow lifetime productivityJohn Blue
Effects of preweaning factors on sow lifetime productivity - Dr. Joe Cassady, from the 2012 Allen D. Leman Swine Conference, September 15-18, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2012-leman-swine-conference-material
This document contains an abstract from a conference on Porcine Circovirus diseases. The abstract describes a field study comparing the effectiveness of three different PCV2 piglet vaccines (CIRCOVAC, Vaccine A, and Vaccine B) on a large Russian farm. Over 4,000 piglets were randomly assigned to receive one of the three vaccines and were monitored for average daily weight gain and mortality in the post-weaning and finisher stages. The results showed CIRCOVAC and Vaccine A performed similarly in terms of weight gain and mortality, while Vaccine B results were slightly lower. The study demonstrates the ability of CIRCOVAC to control PCV2 under field conditions in Russia comparable to another leading
6.epidemiology and management of brd in dairy heifer replacementsMerial EMEA
This document summarizes research on managing bovine respiratory disease (BRD) in dairy heifer replacements. It discusses the importance of monitoring health, as BRD incidence can compromise the productive life of dairy cows. The research examined the effects of vaccination programs, immune status, housing density, and antibiotic treatment on BRD incidence and animal performance. Results showed that forming groups before weaning increased feed intake and that treating calves with an antibiotic when moving to group housing reduced BRD incidence without affecting growth. Overall, monitoring health and taking rapid action against BRD is important for herd sustainability.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, more total born piglets, and better reproductive parameters compared to non-vaccinated gilts. Field studies demonstrate significant breeding performance improvements after gilt vaccination against PCV2.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, more total born piglets, and better reproductive parameters compared to non-vaccinated gilts. Field studies demonstrate significant breeding performance improvements after gilt vaccination against PCV2.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, and increased total born piglets compared to non-vaccinated gilts. Field studies demonstrate PCV2 vaccination of gilts and sows can significantly improve reproductive performance.
Dr. Jennifer Hasty - Elimination of Porcine Epidemic Diarrhea Virus from A Mu...John Blue
Elimination of Porcine Epidemic Diarrhea Virus from A Multiplier Sow Herd and Its Effects on Reproductive Parameters - Dr. Jennifer Hasty, from the 2018 Allen D. Leman Swine Conference, September 15-18, 2018, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2018-leman-swine-conference-material
The document summarizes research on the efficacy of the Circovac vaccine in controlling PCVD (Porcine Circovirus Disease) under field conditions in Brazil. Two trials were conducted involving 1200 piglets total across two farms. Piglets vaccinated with Circovac at weaning showed lower wasting and mortality rates compared to non-vaccinated piglets. Vaccinated piglets also exhibited increased daily weight gain and improved feed conversion. Post-mortem examination found vaccinated piglets had significantly fewer lung lesions. The research concluded that Circovac vaccination of weaned piglets can effectively control PCVD and improve productivity on farms in Brazil.
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
PCV2 is highly prevalent in swine herds worldwide. The document summarizes research showing that:
1) Pigs are born already infected with PCV2, as the virus is present in pre-farrowing sows and transmitted to piglets in utero or during birth.
2) Piglets remain viremic for life even in the presence of antibodies, as PCV2 infection causes lifelong persistent infection.
3) The farrowing environment is thoroughly contaminated with PCV2, exposing growing piglets to constant viral challenge from the sow and environment.
Human Ad-5 based FMD vaccines (T. de Los Santos)EuFMD
The European Commission for the Control of Foot-and-Mouth Disease (EuFMD), one of FAO’s oldest Commissions, came into being on the 12th June 1954, with the pledge of the sixth founding member state to the principles of a coordinated and common action against Foot-and-mouth Disease.
The document summarizes the results of a study comparing the efficacy of two PCV2 vaccines (Circovac and CircoFlex) on piglets in an Italian farm. Over 1050 piglets were randomly assigned to three groups - one vaccinated with Circovac, one with CircoFlex, and a control group. The vaccinated groups showed improved average daily weight gain of 22g/day compared to the control group. Mortality and runts were also lower in the vaccinated groups. The study provides evidence of the zootechnical benefits of PCV2 vaccination on pig farms.
VAXXITEK HVT + IBD - Field Study - Spain - MerialMerial EMEA
This field study compared the effects of Vaxxitek HVT+IBD vaccine versus an intermediate IBD vaccine on broiler production performance and meat quality in Eastern Spain. The study involved 24 farms randomly divided into two groups, with 12 farms vaccinating birds with Vaxxitek and 12 farms vaccinating with the intermediate vaccine. Results showed that birds vaccinated with Vaxxitek had significantly higher average daily gain, lower feed conversion ratio, lower mortality rates, and lower early production losses compared to birds vaccinated with the intermediate vaccine. Vaxxitek also provided a slight improvement in breast muscle color quality.
VAXXITEK HVT + IBD - Field Study - Egypt - MerialMerial EMEA
This document summarizes the results of a field study comparing the use of VAXXITEK HVT+IBD vaccine to a standard IBD vaccination program in commercial broilers in Egypt. Three consecutive cycles of 155,000 broilers were given either the VAXXITEK vaccine at day-of-hatch or the standard IBD program involving live IBD vaccines at day-of-hatch and day 14. The VAXXITEK vaccine provided equivalent protection against vvIBD as the standard program while improving performance parameters such as 10 points lower early postmortem inspection condemnation, higher livability, heavier body weight, and better feed conversion rate, resulting in an economic benefit of $0.245/kg body weight.
This document discusses strategies for controlling Porcine Circovirus Type 2 (PCVD) in pigs. It notes that the disease has changed over time from an acute to a chronic form. Three main factors determine the risk of PCVD: high viral pressure, poor passive immunity in piglets, and young age at exposure. Vaccination of sows provides passive immunity to piglets while vaccination of piglets provides active immunity. The optimal strategy depends on farm size, co-infections present, and reproductive performance goals. A basic program vaccinating only sows is most cost-effective while a complete program vaccinating sows and piglets provides maximum protection. Future segmentation of farms may involve basic programs for small farms and assault or
Vila et al. Improvement of herd performance parameters after sow and piglet v...Merial EMEA
This document summarizes the results of a case study conducted on a 2,700 sow farm in Bulgaria that implemented a full herd vaccination program against PCV2 using CIRCOVAC. The program involved vaccinating piglets at 28-30 days and sows. Results showed improvements in herd performance parameters, including increased litter size from 13 to 17.8 total born piglets, decreased days to 100kg by 5.3 days, improved daily weight gain, and stabilized health status by decreasing gastric ulcers and respiratory signs. The owner considers CIRCOVAC vaccination as a key tool for farm management and competitiveness.
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
Natural Infection, Immunity & Prevalence of PCV2 - Dr. Michael Murtaugh and Dr. Cheryl Dvorak, University of Minnesota, USA , from the Boehringer Ingelheim Pre-AASV Conference, February 28, 2014 - Dallas, TX
More presentations at http://www.swinecast.com/2014-boehringer-ingelheim-aasv
The document summarizes a 3-year field study on the use of CIRCOVAC piglet vaccination in 69 French farms. The main findings were:
1) Over 500,000 piglets were vaccinated between 3-6 weeks with good safety and most farmers continued vaccination.
2) There was a significant reduction in mortality rates and a sharp increase in average daily gain (ADG), reducing fattening periods by up to 20 days.
3) Focusing on 3 farms in more detail, vaccination was associated with decreased mortality, increased carcass weight and homogeneity, and reduced lung lesions compared to non-vaccinated piglets.
The document reports on Muhammad Tanveer Shah's 16-week internship at the Government Poultry Farm in Quetta from September 19, 2011 to January 8, 2012. The farm breeds layers and broilers for commercial egg and meat production. Management of the layers and broilers involves selection of breeds, housing, feeding, vaccination schedules, and disease control protocols carried out on a weekly basis to optimize production.
Bi pre aasv health seminar castro ppt (1) dw020810 sans picsJohn Blue
This document summarizes the experience of a Chilean pig farm with porcine circovirus type 2 (PCV2) and different PCV2 vaccination protocols from 2007-2009. It finds that vaccination with Ingelvac CircoFLEX at 20 days of age resulted in lower attrition, culling, and mortality rates compared to vaccination with Circumvent from 5-21 days of age or no vaccination. Average marketed pigs per period were also highest with CircoFLEX vaccination. Mortality rates were highest during a PCV2-associated disease (PCVAD) outbreak when no vaccination was used. Intestinal torsion was a top cause of mortality.
Bi pre aasv health seminar castro ppt (1) dw020810 sans picsJohn Blue
This document summarizes the experience of a Chilean pig farm with porcine circovirus type 2 (PCV2) and different PCV2 vaccination protocols from 2007-2009. It finds that vaccination with Ingelvac CircoFLEX at 20 days of age resulted in lower attrition, culling, and mortality rates compared to vaccination with Circumvent at 5-21 days of age or no vaccination. Average marketed pigs per period were also highest with CircoFLEX vaccination. Mortality rates were highest during a PCV2-associated disease (PCVAD) outbreak in 2007 before vaccines were widely used. Intestinal torsion was a top cause of mortality.
Dr. Barry Kerkaert - Applying Research to Decision Making to Maximize Returns...John Blue
Applying Research to Decision Making to Maximize Returns at Pipestone - Dr. Barry R. Kerkaert, Director of Grow Finish Management, Pipestone Vet Clinic, from the 2012 Boehringer Ingelheim Swine Health Seminar, August 9-11, 2012, Wrightsville Beach, NC, USA.
More presentations at http://www.swinecast.com/2012-boehringer-ingelheim-carolina-swine-health-seminar
Dr. Joe Cassady - Effects of preweaning factors on sow lifetime productivityJohn Blue
Effects of preweaning factors on sow lifetime productivity - Dr. Joe Cassady, from the 2012 Allen D. Leman Swine Conference, September 15-18, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2012-leman-swine-conference-material
This document contains an abstract from a conference on Porcine Circovirus diseases. The abstract describes a field study comparing the effectiveness of three different PCV2 piglet vaccines (CIRCOVAC, Vaccine A, and Vaccine B) on a large Russian farm. Over 4,000 piglets were randomly assigned to receive one of the three vaccines and were monitored for average daily weight gain and mortality in the post-weaning and finisher stages. The results showed CIRCOVAC and Vaccine A performed similarly in terms of weight gain and mortality, while Vaccine B results were slightly lower. The study demonstrates the ability of CIRCOVAC to control PCV2 under field conditions in Russia comparable to another leading
6.epidemiology and management of brd in dairy heifer replacementsMerial EMEA
This document summarizes research on managing bovine respiratory disease (BRD) in dairy heifer replacements. It discusses the importance of monitoring health, as BRD incidence can compromise the productive life of dairy cows. The research examined the effects of vaccination programs, immune status, housing density, and antibiotic treatment on BRD incidence and animal performance. Results showed that forming groups before weaning increased feed intake and that treating calves with an antibiotic when moving to group housing reduced BRD incidence without affecting growth. Overall, monitoring health and taking rapid action against BRD is important for herd sustainability.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, more total born piglets, and better reproductive parameters compared to non-vaccinated gilts. Field studies demonstrate significant breeding performance improvements after gilt vaccination against PCV2.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, more total born piglets, and better reproductive parameters compared to non-vaccinated gilts. Field studies demonstrate significant breeding performance improvements after gilt vaccination against PCV2.
The document discusses managing PCV2 infection in gilts through vaccination. It presents results from several farms that show vaccinating gilts against PCV2 with Circovac led to improved acclimatization of gilts, reduced clinical signs, increased weight gain, higher farrowing weights, and increased total born piglets compared to non-vaccinated gilts. Field studies demonstrate PCV2 vaccination of gilts and sows can significantly improve reproductive performance.
Dr. Jennifer Hasty - Elimination of Porcine Epidemic Diarrhea Virus from A Mu...John Blue
Elimination of Porcine Epidemic Diarrhea Virus from A Multiplier Sow Herd and Its Effects on Reproductive Parameters - Dr. Jennifer Hasty, from the 2018 Allen D. Leman Swine Conference, September 15-18, 2018, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2018-leman-swine-conference-material
The document summarizes research on the efficacy of the Circovac vaccine in controlling PCVD (Porcine Circovirus Disease) under field conditions in Brazil. Two trials were conducted involving 1200 piglets total across two farms. Piglets vaccinated with Circovac at weaning showed lower wasting and mortality rates compared to non-vaccinated piglets. Vaccinated piglets also exhibited increased daily weight gain and improved feed conversion. Post-mortem examination found vaccinated piglets had significantly fewer lung lesions. The research concluded that Circovac vaccination of weaned piglets can effectively control PCVD and improve productivity on farms in Brazil.
Dr. Michael Murtaugh and Dr. Cheryl Dvorak - Natural Infection, Immunity & Pr...John Blue
PCV2 is highly prevalent in swine herds worldwide. The document summarizes research showing that:
1) Pigs are born already infected with PCV2, as the virus is present in pre-farrowing sows and transmitted to piglets in utero or during birth.
2) Piglets remain viremic for life even in the presence of antibodies, as PCV2 infection causes lifelong persistent infection.
3) The farrowing environment is thoroughly contaminated with PCV2, exposing growing piglets to constant viral challenge from the sow and environment.
Human Ad-5 based FMD vaccines (T. de Los Santos)EuFMD
The European Commission for the Control of Foot-and-Mouth Disease (EuFMD), one of FAO’s oldest Commissions, came into being on the 12th June 1954, with the pledge of the sixth founding member state to the principles of a coordinated and common action against Foot-and-mouth Disease.
The document summarizes the results of a study comparing the efficacy of two PCV2 vaccines (Circovac and CircoFlex) on piglets in an Italian farm. Over 1050 piglets were randomly assigned to three groups - one vaccinated with Circovac, one with CircoFlex, and a control group. The vaccinated groups showed improved average daily weight gain of 22g/day compared to the control group. Mortality and runts were also lower in the vaccinated groups. The study provides evidence of the zootechnical benefits of PCV2 vaccination on pig farms.
VAXXITEK HVT + IBD - Field Study - Spain - MerialMerial EMEA
This field study compared the effects of Vaxxitek HVT+IBD vaccine versus an intermediate IBD vaccine on broiler production performance and meat quality in Eastern Spain. The study involved 24 farms randomly divided into two groups, with 12 farms vaccinating birds with Vaxxitek and 12 farms vaccinating with the intermediate vaccine. Results showed that birds vaccinated with Vaxxitek had significantly higher average daily gain, lower feed conversion ratio, lower mortality rates, and lower early production losses compared to birds vaccinated with the intermediate vaccine. Vaxxitek also provided a slight improvement in breast muscle color quality.
VAXXITEK HVT + IBD - Field Study - Egypt - MerialMerial EMEA
This document summarizes the results of a field study comparing the use of VAXXITEK HVT+IBD vaccine to a standard IBD vaccination program in commercial broilers in Egypt. Three consecutive cycles of 155,000 broilers were given either the VAXXITEK vaccine at day-of-hatch or the standard IBD program involving live IBD vaccines at day-of-hatch and day 14. The VAXXITEK vaccine provided equivalent protection against vvIBD as the standard program while improving performance parameters such as 10 points lower early postmortem inspection condemnation, higher livability, heavier body weight, and better feed conversion rate, resulting in an economic benefit of $0.245/kg body weight.
VAXXITEK HVT + IBD - Field Study - China - MerialMerial EMEA
This document summarizes a field study comparing the use of VAXXITEK HVT+IBD vaccine to a live IBD hot vaccine program in colored chicken flocks in China. The study was conducted on four farms totaling over 160,000 birds in the VAXXITEK group and over 300,000 birds in the control group receiving the live IBD vaccine. Results showed improved liveability, weight gain, feed conversion ratio, and economic performance in the VAXXITEK group along with reduced medication costs. Overall, the study demonstrated benefits of VAXXITEK including improved production efficiency and economic returns compared to the live IBD vaccine program.
VAXXITEK HVT + IBD - Field Study - United Kingdom - MerialMerial EMEA
Oakland Farm Eggs Ltd. is the largest producer of colony eggs in the UK, rearing over 2 million pullets per year. They were experiencing problems with variable chick quality, poor flock uniformity, high Marek's disease challenge, and severe IBD infections causing 30% mortality. They administered 4 live hot IBD vaccinations but saw variable egg production. In 2010, they started vaccinating flocks with Vaxxitek HVT+IBD which improved overall bird health, achieved good uniform body weights, and allowed removal of the 4 on-farm live IBD vaccinations. Data from 2012 showed improved bodyweights, uniformity and laying performance since adopting the Vaxxitek vaccination.
VAXXITEK HVT + IBD - Field Study - France - MerialMerial EMEA
A field study was conducted in France to compare the laying performance of commercial brown layers vaccinated with Vaxxitek HVT+IBD versus controls vaccinated with a live intermediate IBD vaccine. Over 250 birds per group were reared on a pullet and layer farm and housed in enriched cages. Results showed that the Vaxxitek group had a 3.88 egg/hen higher laying rate and higher average egg weight than the controls. Growth was also improved in the Vaxxitek group as they had a higher body weight at 5 weeks of age. In conclusion, Vaxxitek vaccination benefits included higher pullet weight at point of lay, improved laying performance and egg quality.
Apvs2013 09 vosloo et al.-o1 manisa efficacy vs viet fmd strain in pigMerial EMEA
This study tested the efficacy of an O1 Manisa high potency vaccine against challenge with the O/Vietnam/2010 strain in pigs. Pigs were vaccinated 4 and 7 days prior to challenge. Most vaccinated pigs were protected from clinical disease at both timepoints. Virus RNA was detected in nasal secretions of vaccinated pigs for shorter durations than in unvaccinated controls. Vaccinated pigs shed insufficient virus to infect direct contact pigs. The vaccine decreased virus excretion and transmission, suggesting it could help control disease outbreaks when used with biosecurity measures.
Apvs2013 04 kagawa et al.-importance of continuation of pcv2 sow vaccination ...Merial EMEA
1) This case report describes a 120-sow farm in Japan that implemented PCV2 vaccination of sows in 2008 and saw a reduction in post-weaning mortality without vaccinating piglets.
2) After sow vaccination, the farm's post-weaning mortality rate decreased substantially from around 20% to an average of 5.2% in 2012, though it fluctuated due to other disease issues.
3) Testing showed that PCV2 viral loads decreased after sow vaccination such that the virus was not detected in pigs of any age three years after vaccination began. Continued sow vaccination provided strong immunity and global protection across the farm.
Chapat et al.-orf1 et orf2 cmi with CIRCOVAC vaccination in sowsMerial EMEA
This study assessed the cell-mediated immune response against PCV2 ORF1 and ORF2 proteins in pigs vaccinated with an inactivated PCV2 vaccine. The results showed that vaccination induced gamma interferon production against both ORF1 and ORF2, primed pigs for interleukin-2 secretion after challenge, and stimulated antibody responses. In contrast, unvaccinated pigs only developed immune responses after challenge. The cellular immune response detected is expected to contribute to reduced PCV2 replication in vaccinated pigs. This highlights the importance of including both ORF1 and ORF2 in PCV2 vaccine design.
Apvs2013 02 merdy et al.-comparison circovac vs competitors on adwg mortality...Merial EMEA
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Apvs2013 10 lee et al.-trypanosomiasis in pigs in malaysiaMerial EMEA
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This document summarizes a serological survey of Aujeszky's disease vaccination in an Italian pig herd. The herd vaccinated gilts, sows, growers, and fatteners using a vaccine called AKIPOR 6.3 mixed with another vaccine. Blood samples from gilts, sows, and fatteners showed high antibody levels against Aujeszky's disease, indicating the mixed vaccination program was effective at maintaining immunity. The survey results demonstrated that mixing AKIPOR 6.3 with an influenza vaccine did not negatively impact the potency of the Aujeszky's disease component of the vaccine.
Salvini et al.-Introduction of prssv vaccination with PROGRESSIS® in an itali...Merial EMEA
This document summarizes a case report on the effects of introducing PRSSv vaccination with Progressis in addition to existing PCV2 vaccination with Circovac in an Italian pig farm. Key results included an improvement in the farrowing rate from 82.8% to over 90% after introducing Progressis vaccination for gilts and sows. Other positive impacts were a steady increase in litter size from 13.26 to 15.01 piglets born alive per litter between 2010-2012, and an increase in piglets weaned per sow from 24.87 to 27.42 over the same period despite lengthening the reproductive cycle. The case report concluded that PRSSv vaccination with Progressis was an effective tool to help improve
Apvs2013 06 castellan et al.-clinical case report of h1 n1pdm in italyMerial EMEA
This document summarizes a clinical case report of an outbreak of pandemic H1N1 influenza virus (H1N1pdm) in an Italian pig farm between July 2012 and March 2013. The farm experienced increased respiratory disease and mortality in post-weaned pigs, testing confirmed the presence of H1N1pdm virus. A vaccination program was implemented using an inactivated trivalent swine influenza vaccine. Following vaccination of sows and piglets, clinical signs reduced and virus detection decreased, controlling the H1N1pdm outbreak.
Aasv2014 daresta et al. comparative pcv2 fetal protection-posterMerial EMEA
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Aasv2014 callen et al. vaccination compliance to pcv2 using a dth testMerial EMEA
This document describes two trials that tested a delayed type hypersensitivity (DTH) test to detect compliance with PCV2 vaccination. In the first trial, vaccinated pigs all showed a significant skin reaction to antigen injection, while 50% of unvaccinated pigs reacted. The reaction was strongest 20-24 hours after injection. Histology confirmed a type IV DTH response. The second trial found nearly all pigs vaccinated with CIRCOVAC reacted, while only 25% of those vaccinated with another PCV2 vaccine reacted. The DTH test shows potential as a practical way to check compliance with CIRCOVAC vaccination. Further studies are needed to improve specificity and standardize the technique in field conditions.
The document discusses the 6th European Symposium of Poultry and Health Management (ESPHM) which was held in Sorrento, Italy. It was a scientific conference focused on providing reports for animal health professionals. The symposium aimed to share the latest research and information regarding animal health.
Ipvs2014 02 mortensen et al.-pcv2 circulation control in danish fatteners abs...Merial EMEA
This study assessed the control of PCV2 viral circulation in Danish slaughter pigs vaccinated with CIRCOVAC at 3 weeks of age. Blood samples were taken from 8 farms at various weight intervals and tested for PCV2 viral load and antibodies. No PCV2 DNA was detected in any samples, and antibody levels remained low, indicating an absence of PCV2 circulation. Vaccination with CIRCOVAC at 3 weeks of age provided excellent control of PCV2 throughout the fattening period, protecting against PCVD.
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06 m grozeva
1. 4TH MERIAL FORUM
HAVE WE GOT PCVD &
SWINE INFLUENZA UNDER
CONTROL?
2. PCVD
Moderator: Dr Stéphane Imbert
• Viral reproductive disorders in sows, an
update 2012. Pr. H. Nauwynck
• Benefits of CIRCOVAC® piglet vaccination
in Hngary. Dr T. Kecskés
• Additional benefits of sow and piglet
CIRCOVAC vaccination: Bulgarian field
experience. Dr M. Grozeva
3. 4TH MERIAL FORUM
HAVE WE GOT PCVD &
SWINE INFLUENZA UNDER
CONTROL?
5. CIRCOVAC : a dual approach for the
total herd performance benefits
Different Different
targets approaches
Piglet performance Reproductive Total herd performance
performance
x
Piglet vaccination Sow vaccination Sow & Piglet
vaccination
7. ROMANIA
SERBIA
110,993,6 km2
MACEDONIA
Bulgaria
TURKEY
GREECE
8. BULGARIA
7 628 103
2007
Moderate and transitional-continental
Huge temperature variation
in swine producing regions
+ 40˚ C - 30˚ C
9. BULGARIA
36 890 accessible sows in 37 farms
Traditional pork consuming people
10. Distribution of industrial (accessible)
pigs in different types of farms
1%
10%
Large Farrow-to-Finish Farms
(>400 pigs)
Small Farrow-to Finish Farms
(<400 pigs)
89% Fatteners Farms
23 farms ≈ 90% of industrial sows
13. Swine farm “Brashlen”
Number of sows – 2700
250 hectares
Genetic - farm № 41
Number of batches – 8
Batch management – 4 days
Type of flow – all in, all out
14. Health status of the farm
PRRS (-)
App (+)
M. hyo (+)
Aujezsky (-)
16. Vaccination against PCV2 - Why?
Farm performance before vaccination
No visible reproductive disorders
Farrowing Rate >90%
ADWG in growers – 0.566 kg
ADWG in fatteners – 0.983 kg
Stoykov et al. (2011), APVS, Pattaya, Thailand
17. Vaccination against PCV2 - Why?
Farm performance before
vaccination
Increased %
”lightweight” pigs,
especially in fattening
period
Mortality rate - slight
increase in fatteners
(2%)
Single cases of PDNS
18. Vaccination against PCV2 - Why?
Farm performance before vaccination
Necropsy – stomach ulcers
Performance lower than top DanBred farms
Positive PCV2 serology
SUB CLINICAL PCVD
19. No changes meantime
Same genetic
Same feed
Same vaccination program
(except CIRCOVAC)
Same biosecurity
… but the farm is live organism…
20. CIRCOVAC - Piglet MASS
vaccination - PROTOCOL
All pigs at age 29-100 days
Single injection - 0,5 ml, IM
21. CIRCOVAC - Piglet REGULAR
vaccination - PROTOCOL
All pigs at weaning (28-29 days)
Single injection - 0,5 ml, IM
22. Benefits of CIRCOVAC - piglet
vaccination
First (visible)
observations :
Disappeared stomach
ulcers
Very well uniform
piglets
23. Significant improvement of ADWG
Growing Fattening
610 1080
1060 1052*
600
590 1040
590
1020
580 1000
983
570 566 980
960
560
940
550
920
540 900
Before Piglets Before Piglets
+ 24 g ADWG in growers + 69 g ADWG in fatteners
25. After good piglet results – sow
vaccination – WHY?
A lot of confirmations of
influence of PCV2 on
reproduction
26. After good piglet results – sow
vaccination – WHY?
• Very good
farrowing rate…
…but opportunity to
reach better results in
number of
born/weaned piglets
27. CIRCOVAC – Reproduction herd
MASS vaccination - PROTOCOL
Sows, gilts, boars
Start – end of July 2009
Dose – 2 ml, IM, 2 injections, 3 weeks apart
One further injection at least 2 weeks before
farrowing
*in mass vaccination some animals received 1 injection, another - 2
and other -3
28. CIRCOVAC – Sow REGULAR
vaccination - PROTOCOL
One injection at each gestation at least
2 weeks before farrowing
Dose – 2 ml, IM
29. CIRCOVAC – Gilts REGULAR
vaccination - PROTOCOL
Primary vaccination:
Dose – 2 ml, IM, 2 injections, 3 weeks apart,
second injection at least 2 weeks before
mating
Booster:
One injection at least 2 weeks before
farrowing
30. Benefits of CIRCOVAC - sow
vaccination
Total born/litter
18 16* 16,7*
15,5*
16
14
13 13,3
12
10
controls piglets 2010S1 2010S2 2011T1
+ 3,7 born piglets / litter
Control
P<0.05 (Dunett test) Sows vaccinated
31. Benefits of CIRCOVAC - sow
vaccination
Live born/litter
16 14,9*
13,9* 14,2*
14
11,8 12
12
10
controls piglets 2010S1 2010S2 2011T1
+ 3,1 live born piglets / litter
Control
P<0.05 (Dunett test) Sows vaccinated
33. CIRCOVAC - Sow & piglets – REGULAR
vaccination
PROTOCOL
Sow – one injection at least 2 weeks before
each farrowing
Gilts – Primary vaccination – 2 injection, 3
weeks apart, booster – 1 injection, 2 weeks
before farowing
Piglets – one injection at 7 weeks of age
34. IMPORTANT !!!
After mass sow vaccination –
piglets vaccination was postponed to
7 weeks of age
Farrowing Weaning Begin.
of Finishing Slaughter
Weeks of age
28 days 7 weeks
35. CIRCOVAC – Boar – REGULAR
vaccination
6 months apart
Transmission of porcine circovirus
2 (PCV2) by semen
and viral distribution in different
piglet tissues1
Danielle Gava2, Eraldo L. Zanella3,
Nelson Morés4 and Janice R.
Ciacci-Zanella5*
36. CIRCOVAC - Sow + Piglets
The best improvement of ADWG
Growing Fattening
607*
610 602* 1080
1060* 1060*
600 1060 1052*
590
590 1040
580
1020
570
566
1000
560 983
980
550
540 960
940
1
09
s
re
et
01
fo
20
gl
/2
Be
Pi
ts
10
920
le
20
g
pi
s
et
s+
igl
900
w
so
p
s+
Before Piglets sows+ piglets sows+piglets
w
2009 2010/2011
so
+ 41 g ADWG in growers + 77 g ADWG in fatteners
38. Summary of vaccination protocol
2009 Feb Mar Apr May June July Aug Sept Oct Nov Dec
2010 Jan Feb Mar Apr May June July Aug Sept Oct Nov Dec
2011 Jan Feb Mar Apr May June July Aug Sept Oct Nov Dec
2012 Jan Feb Mar Apr May
Piglets Sow + Piglets Regular
Sow + Piglets
39. CONCLUSION
In farm “Brashlen” CIRCOVAC:
increases the reproductive
performances – number of
live born piglets + 3.1 and +
1 weaned pig/litter
increases the kg produced
by sow
40. CONCLUSION
In farm “Brashlen” CIRCOVAC :
improves the pig growth from birth to slaughter
+ 41 g ; + 77 g
reduces the duration to 100 kg – 5,3 days
helps for homogenous pig batches
restore mortality rate
prevent from appearance of stomach ulcers
41. CONCLUSION
CIRCOVAC helps the farm “Brashlen” to have a
good profit at the difficult time with a lots of
crisis…and welfare requirements…
CIRCOVAC regular sow + piglet vaccination is
an investment in that farm with 2700 sows
and a lots of piglets…
42. CONCLUSION
…but ROI are justified already
more than 3 years and prove
definitely that the sow +
piglet vaccination gives the
best performance in farrow-
to-finish farm.