VAXXITEK HVT + IBD - Field Study - United Kingdom - Merial
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Oakland Farm Eggs Ltd. is the largest producer of colony eggs in the UK, rearing over 2 million pullets per year. They were experiencing problems with variable chick quality, poor flock uniformity, high Marek's disease challenge, and severe IBD infections causing 30% mortality. They administered 4 live hot IBD vaccinations but saw variable egg production. In 2010, they started vaccinating flocks with Vaxxitek HVT+IBD which improved overall bird health, achieved good uniform body weights, and allowed removal of the 4 on-farm live IBD vaccinations. Data from 2012 showed improved bodyweights, uniformity and laying performance since adopting the Vaxxitek vaccination.
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This document summarizes the results of a case study conducted on a 2,700 sow farm in Bulgaria that implemented a full herd vaccination program against PCV2 using CIRCOVAC. The program involved vaccinating piglets at 28-30 days and sows. Results showed improvements in herd performance parameters, including increased litter size from 13 to 17.8 total born piglets, decreased days to 100kg by 5.3 days, improved daily weight gain, and stabilized health status by decreasing gastric ulcers and respiratory signs. The owner considers CIRCOVAC vaccination as a key tool for farm management and competitiveness.
Aasv2014 daresta et al. comparative pcv2 fetal protection-poster
This study evaluated the protective effects of two PCV2 vaccines (Vaccine A and Vaccine B) against fetal PCV2 infection in pigs. Gilts were vaccinated with one of the vaccines or unvaccinated as controls. After artificial insemination with PCV2-spiked semen, fetuses, placentas, and amniotic fluid were tested for PCV2. Vaccine A significantly reduced PCV2 positivity in fetuses compared to unvaccinated controls, but Vaccine B increased PCV2 positivity in placentas and amniotic fluid. The results suggest Vaccine A may better protect against subclinical fetal PCV2 infection than Vaccine B.
Aasv2014 callen et al. vaccination compliance to pcv2 using a dth test
This document describes two trials that tested a delayed type hypersensitivity (DTH) test to detect compliance with PCV2 vaccination. In the first trial, vaccinated pigs all showed a significant skin reaction to antigen injection, while 50% of unvaccinated pigs reacted. The reaction was strongest 20-24 hours after injection. Histology confirmed a type IV DTH response. The second trial found nearly all pigs vaccinated with CIRCOVAC reacted, while only 25% of those vaccinated with another PCV2 vaccine reacted. The DTH test shows potential as a practical way to check compliance with CIRCOVAC vaccination. Further studies are needed to improve specificity and standardize the technique in field conditions.
ESPHM2014 MERIAL Momentum
This document contains an abstract from a conference on Porcine Circovirus diseases. The abstract describes a field study comparing the effectiveness of three different PCV2 piglet vaccines (CIRCOVAC, Vaccine A, and Vaccine B) on a large Russian farm. Over 4,000 piglets were randomly assigned to receive one of the three vaccines and were monitored for average daily weight gain and mortality in the post-weaning and finisher stages. The results showed CIRCOVAC and Vaccine A performed similarly in terms of weight gain and mortality, while Vaccine B results were slightly lower. The study demonstrates the ability of CIRCOVAC to control PCV2 under field conditions in Russia comparable to another leading
ESPHM 2014 MERIAL momentum cover
The document discusses the 6th European Symposium of Poultry and Health Management (ESPHM) which was held in Sorrento, Italy. It was a scientific conference focused on providing reports for animal health professionals. The symposium aimed to share the latest research and information regarding animal health.
Ipvs2014 02 mortensen et al.-pcv2 circulation control in danish fatteners abs...
This study assessed the control of PCV2 viral circulation in Danish slaughter pigs vaccinated with CIRCOVAC at 3 weeks of age. Blood samples were taken from 8 farms at various weight intervals and tested for PCV2 viral load and antibodies. No PCV2 DNA was detected in any samples, and antibody levels remained low, indicating an absence of PCV2 circulation. Vaccination with CIRCOVAC at 3 weeks of age provided excellent control of PCV2 throughout the fattening period, protecting against PCVD.
Ipvs2014 01 chapat et al-preliminary results cmi circovac piglets abstract
The document summarizes preliminary results from a study on the cell-mediated immune response following vaccination with CIRCOVAC in piglets. The study found that vaccinated piglets had higher levels of IFN-γ producing cells after re-stimulation with PCV2 at 21 and 49 days compared to unvaccinated piglets. Additionally, vaccinated piglets continued to produce IFN-γ in the absence of re-stimulation, suggesting that antigen presenting cells loaded with PCV2 antigen were persisting and presenting antigen to T cells for an extended period after vaccination. Co-culture of purified antigen presenting cells and T cells from vaccinated piglets produced IFN-γ without ex vivo stimulation, supporting the hypothesis of sustained antigen presentation following
12 merialberlinhansnauwynck
The document discusses how various viral pathogens can cause reproductive problems in sows through general disease, replication in the reproductive tract leading to placenta damage, or reaching embryos/fetuses via contaminated semen or transplacental spread. It outlines the stages of gestation where embryos are susceptible to infection and the potential clinical outcomes for fetuses and sows depending on the virus and timing of infection.
05 flu s lee
This document discusses influenza in humans and pigs, comparing their epidemiology and control. It covers topics like antigenic drift vs shift, annual impacts of seasonal influenza, goals for influenza vaccination, recommendations for vaccine strain changes, and the human-animal interface of influenza. Sanofi Pasteur is highlighted as a global leader in human vaccines with a vision of protecting health worldwide through superior vaccines.
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