This document summarizes the care of a 55-year-old male patient with type 2 diabetes who recently relocated. At his initial visit, his HbA1c was 11.2 and BMI was 31. The document outlines assessments done, treatment goals discussed, and a treatment plan involving lifestyle changes and medication adjustments. At a 3-month follow-up visit, some improvements were seen but challenges remained. The doctor discusses continuing treatment to further improve the patient's condition and manage his diabetes and related risks.
Paul Ciechanowksi at Consumer Centric Health, Models for Change '11HealthInnoventions
A Primary Care Program for Patients with Complex Chronic Disease and Depression. Paul Ciechanowski, MD, MPH
Associate Professor, Dept. of Psychiatry
Team Psychiatrist, UW Diabetes Care Center
Director UW Center for Training
University of Washington, Seattle, Washington
Slides to Guide Reducing Cardiovascular Risk in Type 2 Diabetes: What I Do an...hivlifeinfo
Slides to Guide Reducing Cardiovascular Risk in Type 2 Diabetes: What I Do and Why.2018
Zachary T. Bloomgarden, MD, MACE
Program Director
Mikhail N. Kosiborod, MD
Pamela Kushner, MD, FAAFP
Format: Microsoft PowerPoint (.ppt)
File Size: 923 KB
Released: June 29, 2018
Paul Ciechanowksi at Consumer Centric Health, Models for Change '11HealthInnoventions
A Primary Care Program for Patients with Complex Chronic Disease and Depression. Paul Ciechanowski, MD, MPH
Associate Professor, Dept. of Psychiatry
Team Psychiatrist, UW Diabetes Care Center
Director UW Center for Training
University of Washington, Seattle, Washington
Slides to Guide Reducing Cardiovascular Risk in Type 2 Diabetes: What I Do an...hivlifeinfo
Slides to Guide Reducing Cardiovascular Risk in Type 2 Diabetes: What I Do and Why.2018
Zachary T. Bloomgarden, MD, MACE
Program Director
Mikhail N. Kosiborod, MD
Pamela Kushner, MD, FAAFP
Format: Microsoft PowerPoint (.ppt)
File Size: 923 KB
Released: June 29, 2018
Recently, several novel glucose-lowering targets have had drugs developed. This has resulted in several new drugs that have been approved for the local market to treat hyperglycaemia in patients with type 2 diabetes.
This presentation will attempt to provide:
A concise summary of these drugs for an Intensive Care Physician.
A pragmatic framework for what the non-Endocrinology Doctor should do with these drugs whilst the patient is in, and being discharged from, the Intensive Care Unit.
An outline of current trials evaluating glycaemia in the Intensive Care Unit.
A correlation study to determine the effect of diabetes self management on di...Kurt Naugles M.D., M.P.H.
Self-Management in this presentation refers to those activities people undertake in an effort to promote health, prevent disease, limit illness, and restore well being. Several investigators contend that self-management be made a major component of many patient health-care strategy (Glasgow, et al., 2001; Wagner, et al., 2001). Currently, nearly 125 million Americans suffer from chronic debilitating illnesses (Anderson, 2000). These national figures clearly underscore the need to develop a multidimensional approach in regards to disease management. Accordingly, measures that incorporate the patient’s perspective in managing his or her health should be explored.
Diabetes mellitus is among those conditions suspected to be highly influenced by self-management activities (Sprangers, et. al., 2000). If benefits do indeed exist, they need to be fully evidenced. The investigation presented here sought to examine the role self management plays in the health outcomes of individuals living with diabetes.
Monoclonal antibodies (MAbs), guided by molecular studies and personalised medicine are changing the face of clinical medicine. They hold the promise of controlling diseases and improving survival whilst reducing the side effects of some ‘traditional’ therapies. MAbs are being used in conditions familiar to intensivists such as asthma, invasive candidiasis, RSV infection, reversal of novel anticoagulants and clostridium difficile infection as well as in those less commonly seen by intensivists such as multiple sclerosis, migraine, rheumatoid arthritis and numerous malignancies. Side effects of MAb treatment pose particular challenges for intensivists and range from cytokine release syndrome to autoimmune states (such as colitis, endocrinopathies, skin reactions), pneumonitis, thromboemboli, and infections. Pharmcokinetic interactions of MAbs with other drugs remain poorly studied and may be immune dependent, cytokine dependent or target dependent. Our traditional approach of triaging patients for ICU, based on organ failures and ‘prognosis of underlying disease’ is going to be challenged by MAbs with their disease modifying properties and unique side effects.
Effectiveness of Continuous Remote Care and Nutritional Ketosis for Type 2 Di...James McCarter
Society of Behavioral Medicine Annual Meeting, New Orleans,
April 14, 2018. eHealth Carbohydrate-Reduced Diet and Lifestyle
Programs for Adults with Type 2 Diabetes: Three Approaches
Transportation and Total Health - Arlington Mobility Lab Lunch and LearnTed Eytan, MD, MS, MPH
Why would a physician and a health system executive be interested in transportation? A conversation with nationally recognized Arlington, VA Mobility lab, and myself and Keith Montgomery, Executive Director of the Center for Total Health
Effect of Patient Counseling in Improving Physical and Mental Health of Type-...Gangula Amareswara Reddy
The present study concluded that chronic diseases like diabetes affect the quality of life of patients.As the main goal of any medical care is the improvement of the patients’ overall quality of life, the clinical pharmacist imparted patient education through counseling has a major role in improving the physical as well as mental health outcomes.
Dyslipidemia management an evidence based approachDr Vivek Baliga
In this presentation by Dr Vivek Baliga, he discusses the different available statins and how you can choose the right one in different clinical situations. See articles from Dr Baliga on http://drvivekbaliga.net
Recently, several novel glucose-lowering targets have had drugs developed. This has resulted in several new drugs that have been approved for the local market to treat hyperglycaemia in patients with type 2 diabetes.
This presentation will attempt to provide:
A concise summary of these drugs for an Intensive Care Physician.
A pragmatic framework for what the non-Endocrinology Doctor should do with these drugs whilst the patient is in, and being discharged from, the Intensive Care Unit.
An outline of current trials evaluating glycaemia in the Intensive Care Unit.
A correlation study to determine the effect of diabetes self management on di...Kurt Naugles M.D., M.P.H.
Self-Management in this presentation refers to those activities people undertake in an effort to promote health, prevent disease, limit illness, and restore well being. Several investigators contend that self-management be made a major component of many patient health-care strategy (Glasgow, et al., 2001; Wagner, et al., 2001). Currently, nearly 125 million Americans suffer from chronic debilitating illnesses (Anderson, 2000). These national figures clearly underscore the need to develop a multidimensional approach in regards to disease management. Accordingly, measures that incorporate the patient’s perspective in managing his or her health should be explored.
Diabetes mellitus is among those conditions suspected to be highly influenced by self-management activities (Sprangers, et. al., 2000). If benefits do indeed exist, they need to be fully evidenced. The investigation presented here sought to examine the role self management plays in the health outcomes of individuals living with diabetes.
Monoclonal antibodies (MAbs), guided by molecular studies and personalised medicine are changing the face of clinical medicine. They hold the promise of controlling diseases and improving survival whilst reducing the side effects of some ‘traditional’ therapies. MAbs are being used in conditions familiar to intensivists such as asthma, invasive candidiasis, RSV infection, reversal of novel anticoagulants and clostridium difficile infection as well as in those less commonly seen by intensivists such as multiple sclerosis, migraine, rheumatoid arthritis and numerous malignancies. Side effects of MAb treatment pose particular challenges for intensivists and range from cytokine release syndrome to autoimmune states (such as colitis, endocrinopathies, skin reactions), pneumonitis, thromboemboli, and infections. Pharmcokinetic interactions of MAbs with other drugs remain poorly studied and may be immune dependent, cytokine dependent or target dependent. Our traditional approach of triaging patients for ICU, based on organ failures and ‘prognosis of underlying disease’ is going to be challenged by MAbs with their disease modifying properties and unique side effects.
Effectiveness of Continuous Remote Care and Nutritional Ketosis for Type 2 Di...James McCarter
Society of Behavioral Medicine Annual Meeting, New Orleans,
April 14, 2018. eHealth Carbohydrate-Reduced Diet and Lifestyle
Programs for Adults with Type 2 Diabetes: Three Approaches
Transportation and Total Health - Arlington Mobility Lab Lunch and LearnTed Eytan, MD, MS, MPH
Why would a physician and a health system executive be interested in transportation? A conversation with nationally recognized Arlington, VA Mobility lab, and myself and Keith Montgomery, Executive Director of the Center for Total Health
Effect of Patient Counseling in Improving Physical and Mental Health of Type-...Gangula Amareswara Reddy
The present study concluded that chronic diseases like diabetes affect the quality of life of patients.As the main goal of any medical care is the improvement of the patients’ overall quality of life, the clinical pharmacist imparted patient education through counseling has a major role in improving the physical as well as mental health outcomes.
Dyslipidemia management an evidence based approachDr Vivek Baliga
In this presentation by Dr Vivek Baliga, he discusses the different available statins and how you can choose the right one in different clinical situations. See articles from Dr Baliga on http://drvivekbaliga.net
Evidence based treatment approaches for prevention of dementiaRavi Soni
This presentation reviews all the available treatment which have been used for prevention of dementia. The evidences were taken from the Cochrane reviews and library.
The presentation was directed towards Saskatchewan family physicians on exercise prescription for mental health and osteoarthritis in the primary care setting.
Naturopathic Treatmentfor the Prevention ofCardiovascular Disease: A Randomized Pragmatic TrialCCNM – Journal Club Sept 30th, 2010Dugald Seely, ND, MScDirector; Research & Clinical EpidemiologyThe Canadian College of Naturopathic Medicine
Dr Vivek Baliga - Chronic Disease Management In Heart Failure And DiabetesDr Vivek Baliga
Dr Vivek Baliga, Consultant Internal Medicine at Baliga Diagnostics discusses the management of 2 common problems in medical practice - heart failure and type 2 diabetes, including the link between the two. For more articles for patients, visit http://heartsense.in/author/dr-vivek-baliga-b/. For scientific articles and short reviews, visit http://drvivekbaliga.net/
Reducing saturated fat intake for cardiovascular disease: What's the evidence? Health Evidence™
Health Evidence hosted a 60 minute webinar examining the effect of reducing saturated fat intake for cardiovascular disease. Click here for access to the audio recording for this webinar: https://youtu.be/Zwe_JF7Aqb8
Lee Hooper, Reader in Research Synthesis, Nutrition & Hydration in the Norwich Medical School at the University of East Anglia lead the session and presented findings from her latest Cochrane review:
Hooper L., Martin N., Abdelhamid A., & Smith G.D. (2015). Reduction in saturated fat intake for cardiovascular disease . Cochrane Database of Systematic Reviews, 2015, CD011737.
Public health recommendations for fat reduction and modification as prevention of cardiovascular disease have changed little over time. This Cochrane review examines the effect of reducing saturated fat intake through modification on cardiovascular morbidity and mortality through 15 randomised control trials. 17 comparisons with 59,000 participants demonstrate a 17% (RR 0.83; 95% CI 0.72 to 0.96) reduction of cardiovascular events by reducing dietary saturated fat. This webinar will examine the effect of replacing saturated fat with carbohydrate, polyunsaturated and monounsaturated fat on cardiovascular morbidity and mortality, and explore future recommendations.
Our aim is to alleviate human suffering related to diabetes and its complications among those least able to withstand the burden of the disease. From 2002 to March 2017, the World Diabetes Foundation provided USD 130 million in funding to 511 projects in 115 countries. For every dollar spent, the Foundation raises approximately 2 dollars in cash or as in-kind donations from other sources. The total value of the WDF project portfolio reached USD 377 million, excluding WDF’s own advocacy and strategic platforms.
MFLN Nutrition and Wellness New Medications for Type 2 Diabetesmilfamln
Do your patients manage their diabetes by eating well and being active? Or do they need medication to help control their blood sugar? What medications are the most effective and what is new to the market? Tune in to this webinar to guide you through what is available and most effective to help your patients better control their type 2 diabetes.
Learning Objectives:
1. Understand the current paradigm for the treatment of type 2 diabetes.
2. Compare and contrast pros and cons of newer medications for the Treatment of type 2 diabetes.
3. Modify a treatment plan correctly and efficiently based on the side effect profiles of newer medications for the treatment of type 2 diabetes.
Dr. Pramod Tripathi, Founder, Freedom From Diabetes Pvt Ltd on the topic of 'Reversing Diabetes and Lifestyle Disorders' at IFAH held at Le Meridien, Dubai on 16th - 18th December, 2019.
The South African Journal of Diabetes & Vascular Disease presents: Problems and challenges in patients with type 1 diabetes.
Larry A Distiller
Centre for Diabetes and Endocrinology
Johannesburg
http://www.diabetesjournal.co.za
2. Patient Case (webinar)
• New patient, recently relocated
• 55 year old male
• BMI = 31
• HbA1c = 11.2
• Other labs
– Kidney function? Is this an issue for the patient?
–
–
Narrated by Dr. G in webinar format
3. Patient Case (webinar)
• Physical exam
–
–
–
• Medications
–
–
–
Narrated by Dr. G in webinar format
4. Patient Case (webinar)
• Medical history
–
–
• Social history
–
–
• Family history
–
–
Narrated by Dr. G in webinar format
5. Assessing the Patient:
Stages of Change
(end of webinar section)
• Pre-contemplation (Avoidance/denial)
• Contemplation
• Preparation/Determination
• Action/Willpower
• Maintenance
Prochaska JO, et al. J Consult Clin Psychol. 1983;51(3):390-395.
6. Meeting the Patient
Readiness to Change (Patient Video: 5’)
• First interaction with patient
• Assessment of readiness to change
• Why are you here?
7. Assessing the Patient:
Stages of Change
(beginning of 2nd webinar section)
• Pre-contemplation (Avoidance/denial)
• Contemplation
• Preparation/Determination
• Action/Willpower
• Maintenance
Prochaska JO, et al. J Consult Clin Psychol. 1983;51(3):390-395.
8. What is this approach to this patient?
(webinar)
• Review patient interaction
• Current status
– Readiness to change
– Clinical presentation
– History
• Review of risk/benefit
– Diabetes complications
– CV risk
• Goals
– ABCs
– Weight
• Strategy
9. Type 2 Diabetes Risk Assessment
http://www.diabetes.org/are-you-at-risk/diabetes-risk-test/. Accessed February 2014.
10. Heart Attack Risk Assessment
http://cvdrisk.nhlbi.nih.gov/. Accessed February 2014.
Factor
Age years
Gender O Female O Male
Total cholesterol mg/dl
HDL cholesterol mg/dl
Smoker O No O Yes
Systolic BP mmHg
Current hypertension
medication?
O No O Yes
10-Year Risk of Heart Attack
11.
12. Stroke Risk Assessment
1. Are you a female and over the age of 55, OR are you male and over the age of 45? YES NO
2. Do you have high blood pressure, or do you take medication for high blood pressure?
(Ideal Blood Pressure is 120/80) YES NO
Your Blood Pressure: _________________ Date Tested: _________________
3. Do you smoke or have a long history of smoking? YES NO
4. Do you have an irregular heartbeat? YES NO Don’t Know
5. Do you have high cholesterol, OR do you take medication for high cholesterol? YES NO
Don’t Know
6. Cholesterol Levels (if known) HDL: ________ LDL:______ Total:_________
Date Tested: ______________
7. Has your mother, father, siblings, or children had a stroke or heart disease? YES NO
8. Do you exercise less than 3 times per week for 20-30 minutes at a time? YES NO
9. Do you eat a diet high in saturated and/or animal fat? YES NO
10. Are you diabetic? YES NO
11. Are you overweight by 20 pounds or more? YES NO
www.hopeheart.org. Accessed February 2014.
3 or more “YES” see your doctor
13. Treatment Goals: ABCs
• HbA1C
– < 7 % for many people
– Preprandial capillary plasma glucose 70–130 mg/dl
– Peak postprandial (1-2 hours) capillary plasma glucose < 180
mg/dl
• Blood pressure (mmHg)
– Systolic < 140 for most people
– Diastolic < 80 (< 90 per Joint National Committee-8 2014
guideline)
Inzucchi SE, et al. Diabetes Care. 2012;35(6):1364-1379.
http://ndep.nih.gov/publications/PublicationDetail.aspx?PubId=114. Accessed Nov 2013.
James PA, et al. JAMA. 2013 Dec 18. [Epub ahead of print]. http://jama.jamanetwork.com. Accessed Dec 2013.
American Diabetes Association. Diabetes Care. 2014; 37:S14-S80.
14. • Cholesterol – Lipid Profile (mg/dl)
– LDL Cholesterol < 100
LDL < 70 with overt CVD
– HDL Cholesterol Men > 40, Women > 50
– Triglycerides < 150
Inzucchi SE, et al. Diabetes Care. 2012;35(6):1364-1379.
http://ndep.nih.gov/publications/PublicationDetail.aspx?PubId=114. Accessed Nov 2013.
James PA, et al. JAMA. 2013 Dec 18. [Epub ahead of print]. http://jama.jamanetwork.com. Accessed Dec 2013.
American Diabetes Association. Diabetes Care. 2014; 37:S14-S80.
Treatment Goals: ABCs
(cont.)
15. Diabetes Patients at Goal
Stark Casagrande S, et al. Diabetes Care. 2013;36(8):2271-2279.
Ali MK, et al. N Engl J Med. 2013;368(17):1613-1624.
HbA1c 52%
LDL 56%
BP 51%
All 3
19%
16. Other Risk Factors
(end webinar section)
• Smoking
• Sedentary lifestyle
Education Must Be Ongoing
17. Overview of Current Medical Condition
(Patient Video—20’ for section?)
• Diabetes complications
– Consequences of continuing current path
• Diabetes comorbidities
• ABCs (current vs goal?)
– HbA1c
– BP
– Cholesterol
– BMI
18. Risk Assessment (Patient Video)
• Myocardial infarction
• Stroke
• Amputation
• Blindness
• Loss of limb
19. Action Plan
(Patient Video, concluding initial visit)
• Review current patient condition
• Lifestyle changes, specific tools
• Medication changes
20. ?3-Month Follow-Up Visit
(Patient Video)
• HbA1c change
• Body weight change?
• BP, lipids, etc.
• Self-reported lifestyle changes/smoking
cessation
• Medication adherence
• AEs
• Solicit patient feedback on treatment plan
21. Charting the Course (Patient Video)
• Reinforce positive accomplishments
• Review of risks in light of current values
• Areas for improvement
• Review of AEs
• Re-Assessing Goals
• Adjustments to medication?
• Set next visit
22. Case Summary (webinar)
• Initial state
–
–
–
• Follow-up visit
– Improvements
– Challenges
• Next steps, likely course with this patient
23. What Happened at the Patient Visits?
(webinar)
• Readiness to change
• Initial visit
– Exam
– Lab values
– Goals vs current
–
• 3 month visit
–
–
• Treatment plan for this patient
25. Diabetes Drugs Impact Multiple Endpoints
Drug BW
Hyper-
tension
Dys-
lipidemia
Hypoglycemia
Risk
-glucosidase
inhibitors
Neutral Improved
Neutral/
Improved
Low
DPP-4 inhibitors Loss/Neutral Neutral Improved Low
GLP-1 agonists Loss Improved Improved Low
Insulin Gain Neutral* Improved High
Meglitinides Gain Neutral Neutral Moderate
Metformin Loss/Neutral Neutral Improved Low
SGLT2 inhibitors Loss Improved ? Low
Sulfonylureas Gain Neutral Variable Moderate
TZD Gain Improved Improved Low
Basile JN. J Diabetes Complications. 2013;27(3):280-286.
*Hyperinsulinemia is associated with hypertension
26. Therapeutic Options (webinar)
• Initial visit
– How did therapy match patient?
– Successes
– limitations
• Follow-up visit
– How was therapy adjusted?
– Expected impact
– Challenges
27. What Do Patients Want to Know?
(webinar)
• Benefits (long term avoidance of complications)
• Risks (short term adverse effects)
– Weight gain
– Hypoglycemia
–
• Other issues
– Injection anxiety
– Adherence
– Self-image?
– Cost/insurance
– Impact of ACA on diabetes care
Pre-contemplation: Avoidance. That is, not seeing a problem behavior or not considering change. Contemplation: Acknowledging that there is a problem but struggling with ambivalence. Weighing pros and cons and the benefits and barriers to change.Preparation/Determination: Taking steps and getting ready to change.Action/Willpower: Making the change and living the new behaviors, which is an all-consuming activity. Maintenance: Maintaining the behavior change that is now integrated into the person's life.
Pre-contemplation: Avoidance. That is, not seeing a problem behavior or not considering change. Contemplation: Acknowledging that there is a problem but struggling with ambivalence. Weighing pros and cons and the benefits and barriers to change.Preparation/Determination: Taking steps and getting ready to change.Action/Willpower: Making the change and living the new behaviors, which is an all-consuming activity. Maintenance: Maintaining the behavior change that is now integrated into the person's life.
The Prevalence of Meeting A1C, Blood Pressure, and LDL Goals Among PeopleWith Diabetes, 1988–2010SARAH STARK CASAGRANDE, PHDJUDITH E. FRADKIN, MDSHARON H. SAYDAH, PHDKEITH F. RUST, PHDCATHERINE C. COWIE, PHDOBJECTIVE: To determine the prevalence of people with diabetes who meet hemoglobin A1c(A1C), blood pressure (BP), and LDL cholesterol (ABC) recommendations and their currentstatin use, factors associated with goal achievement, and changes in the proportion achievinggoals between 1988 and 2010.RESEARCH DESIGN AND METHODS:Data were cross-sectional from the NationalHealth and Nutrition Examination Surveys (NHANES) from 1988–1994, 1999–2002, 2003–2006, and 2007–2010. Participants were 4,926 adults aged $20 years who self-reported a previousdiagnosis of diabetes and completed the household interview and physical examination(n = 1,558 for valid LDL levels). Main outcome measures were A1C, BP, and LDL cholesterol,in accordance with the American Diabetes Association recommendations, and current use ofstatins.RESULTS: In 2007–2010, 52.5% of people with diabetes achieved A1C ,7.0% (,53 mmol/mol), 51.1% achieved BP ,130/80 mmHg, 56.2% achieved LDL ,100 mg/dL, and 18.8%achieved all three ABCs. These levels of control were significant improvements from 1988 to1994 (all P , 0.05). Statin use significantly increased between 1988–1994 (4.2%) and 2007–2010(51.4%, P , 0.01). Compared with non-Hispanic whites, Mexican Americans were less likely tomeet A1C and LDL goals (P , 0.03), and non-Hispanic blacks were less likely to meet BP andLDL goals (P , 0.02). Compared with non-Hispanic blacks, Mexican Americans were less likelyto meet A1C goals (P , 0.01). Younger individuals were less likely to meet A1C and LDL goals.CONCLUSIONSdDespite significant improvement during the past decade, achieving theABC goals remains suboptimal among adultswith diabetes, particularly in some minority groups.Substantial opportunity exists to further improve diabetes control and, thus, to reduce diabetesrelatedmorbidity and mortality.Diabetes Care 36:2271–2279, 2013N Engl J Med. 2013 Apr 25;368(17):1613-24. doi: 10.1056/NEJMsa1213829.Achievement of goals in U.S. diabetes care, 1999-2010.Ali MK, Bullard KM, Saaddine JB, Cowie CC, Imperatore G, Gregg EW.Erratum in N Engl J Med. 2013 Aug 8;369(6):587. BACKGROUND:Tracking national progress in diabetes care may aid in the evaluation of past efforts and identify residual gaps in care.METHODS:We analyzed data for adults with self-reported diabetes from the National Health and Nutrition Examination Survey and the Behavioral Risk Factor Surveillance System to examine risk-factor control, preventive practices, and risk scores for coronary heart disease over the 1999-2010 period.RESULTS:From 1999 through 2010, the weighted proportion of survey participants who met recommended goals for diabetes care increased, by 7.9 percentage points (95% confidence interval [CI], 0.8 to 15.0) for glycemic control (glycated hemoglobin level <7.0%), 9.4 percentage points (95% CI, 3.0 to 15.8) for individualized glycemic targets, 11.7 percentage points (95% CI, 5.7 to 17.7) for blood pressure (target, <130/80 mm Hg), and 20.8 percentage points (95% CI, 11.6 to 30.0) for lipid levels (target level of low-density lipoprotein [LDL] cholesterol, <100 mg per deciliter [2.6 mmol per liter]). Tobacco use did not change significantly, but the 10-year probability of coronary heart disease decreased by 2.8 to 3.7 percentage points. However, 33.4 to 48.7% of persons with diabetes still did not meet the targets for glycemic control, blood pressure, or LDL cholesterol level. Only 14.3% met the targets for all three of these measures and for tobacco use. Adherence to the recommendations for annual eye and dental examinations was unchanged, but annual lipid-level measurement and foot examination increased by 5.5 percentage points (95% CI, 1.6 to 9.4) and 6.8 percentage points (95% CI, 4.8 to 8.8), respectively. Annual vaccination for influenza and receipt of pneumococcal vaccination for participants 65 years of age or older rose by 4.5 percentage points (95% CI, 0.8 to 8.2) and 6.9 percentage points (95% CI, 3.4 to 10.4), respectively, and daily glucose monitoring increased by 12.7 percentage points (95% CI, 10.3 to 15.1).CONCLUSIONS:Although there were improvements in risk-factor control and adherence to preventive practices from 1999 to 2010, tobacco use remained high, and almost half of U.S. adults with diabetes did not meet the recommended goals for diabetes care.
J Diabetes Complications. 2013 May-Jun;27(3):280-6. doi: 10.1016/j.jdiacomp.2012.12.004. Epub 2013 Feb 1.The potential of sodium glucose cotransporter 2 (SGLT2) inhibitors to reduce cardiovascular risk in patients with type 2 diabetes (T2DM).Basile JN.SourceSeinsheimer Cardiovascular Health Program, Medical University of South Carolina, Charleston, SC 29425, USA. basilejn@musc.eduAbstractType 2 diabetes mellitus (T2DM) significantly increases morbidity and mortality from cardiovascular disease (CVD). Treatments for patients with T2DM have the potential to reduce cardiovascular (CV) risk. This review focuses on the potential of a new class of antidiabetic agents, the sodium glucose cotransporter 2 (SGLT2) inhibitors, to reduce CV risk in patients with T2DM through reductions in hyperglycemia, blood pressure (BP), and body weight. The results of clinical trials of SGLT2 inhibitors are summarized and discussed.